Sanosuke's friend has died from an opium overdose. However, Kenshin and Sanosuke are perplexed at how he even got his hands on the drug, since opium is banned and too expensive for the average person to afford. Then a mysterious woman, Megumi Takani, appears before them. Kenshin and the others fight off Kanryu Takeda's private army who is trying to capture Megumi. However, Megumi is carrying opium...
working directly for the Shogun,
comprised of those
فهي منظّمة سرّيّة من بينهم تعمل مباشرة 
تحت إمرة الشّوغن وتتكوّن من أولئك
que trabajaba para el shogun
y que estaba formada
 काम करने वाली एक गुप्त संघटना थी
और उसमें थे वे लोग जो किसी अन्य ओनमित्सु से
é um sistema de informação
direta do xogum.