re post polio syndrome information needed please dn from nyeda cnsvax uwec edu david nye dn briefly this is a condition in which patients who have significant dn residual weakness from childhood polio notice progression of the dn weakness as they get older one theory is that the remaining motor dn neurons have to work harder and so die sooner if this theory were true the muscle biopsy would show group atrophy evidence of acute loss of enlarged motor units it doesn t instead the biopsy shows scattered angulated atrophic fibers this is more consistent with load shedding by chronically overworked motor neurons the neurons survive at the expense of increasingly denervated muscle slmr e mail jim zisfein factory com jim zisfein
