re is msg sensitivity superstition in article apr cunews carleton ca wcsbeau alfred carleton ca opirg writes many people responded with more anecdotal stories i think its safe to say the original poster is already familiar with such stories presumably he wants hard info to substantiate or refute claims about msg making people ill there has been no hard info provided about msg making people ill that s the point after all like youself someone who can read a scientific paper and apparently come away from it with bizarrely cracked ideas which have nothing to do with the use of this substance in human nutrition have you read olney s work i fail to see how citing results from peer reviewed studies qualifies as bizarrely cracked that s because these peer reviewed studies are not addressing the effects of msg in people they re looking at animal models you can t walk away from this and start ranting about gloom and doom as if there were any documented deleterious health effects demonstrated in humans note that i wouldn t have any argument with a statement like noting that animal administration has pro duced the following blah blah we must be careful about its use in humans this is precisely not what you said tests have been done on rhesus monkeys as well i have never seen a study where the mode of administration was intra ventricular the glu and asp were administered orally some studies used iv and sc intra ventricular is not a normal admin method for food tox studies for obvious reasons you must not have read the peer reviewed works that i referred to or you would never have come up with this brain injection bunk it most certainly is for neurotoxicology you know studies of glutamate involve more than food science pardon me but where are you getting this from have you read the journals have you done a thorough literature search so point us to the studies in humans please i m familiar with the literature and i ve never seen any which relate at all to olney s work in animals and the effects of glutamate on neurons the point is exceeding the window of course they re amino acids note that people with pku cannot tolerate any phenylalanine well actually they have to tolerate some phenylalanine it s a essential amino acid they just try to get as little as is healthy without producing dangerous levels of phenylalanine and its metabolites in the blood olney s research compared infant human diets specifically the amount of freely available glu in mother s milk versus commercial baby foods vs typical lunch items from the standard american diet such as packaged soup mixes he found that one could exceed the projected safety margin for infant humans by at least four fold in a single meal of processed foods mother s milk was well below the effective dose goodness i m not saying that it s good to feed infants a lot of glutamate supplemented foods it s just that this projected safety margin is a construct derived from animal models and given that you can prove anything you like we re talking prudent policy in infant nutrition here yet you re misrepresenting it as received wisdom read olney s review paper in prog brain res and check his sources they are impecable there is no dispute impeccable there most certainly is a dispute between who over what i would be most interested in seeing you provide peer reviewed non food industry funded citations to articles disputing that msg has no effects whatsoever you mean asserting you re being intellectually dishonest or just plain confused because you re conflating reports which do not necessarily have anything to do with each other olney s reports would argue a potential for problems in human infants but that s not to say that this says anything whatsoever about the use of msg in most foods nor does he provide any studies in humans which indicate any deleterious effects for obvious reasons it says nothing about msg s contribtion to the phenomenon of the chinese restaurant syndrome it says nothing about the frequent inability to replicate anecdotal reports of msg sensitivity in the lab dyer ursa major spdcc com hmm com why am i not surprised dianne murray wcsbeau ccs carleton ca probably one of the dumber remarks you ve made steve dyer dyer ursa major spdcc com aka ima harvard rayssd linus m c spdcc dyer
