Publisher Summary The chapter discusses “real-life” experiences in using semi-structured interviews in qualitative research. The reasons for using semi-structured interviews, the design and development of the questionnaire used, the process of interviewing and choice of interviewees, and some of the problems encountered and overcome are presented in the chapter. The chapter describes the process of conducting the interviews that includes writing up the interviews and other activities, and explores additional problems in interviewing abroad. The chapter first covers a U.K. study and using it as the foundation, draws some contrasts from an EU study. The chapter concludes that the use of semi-structured interviews provides a valuable means to allow researchers to explore their horizons.