Here we report an all-nanosheet-based Li-ion full battery using ZnMn2O4–graphene hybrid nanosheet and LiFePO4 nanosheet as anode and cathode, respectively. The short Li ion diffusion length and open charge transport channel of these two-dimensional (2D) nanostructures enable rapid charge and discharge rate. The all-nanosheet-based full battery exhibits superior rate capability and cycling stability, compared to the control full battery using conventional graphite anode and commercial LiFePO4 cathode. Furthermore, flexible full batteries using these 2D nanostructured electrodes are fabricated in pouch cell form, and exhibit impressive electrochemical stability without structural failure and performance loss under various mechanical bending states.