Objective Identify the correlation of discomfort physical and psychological to social interaction on diabetic ulcer patients. Method This research design used Cross-sectional design was applied in this study with 69 samples that had been recruited from a clinic of wound care in Jakarta, Indonesia. The instruments used in this research were Bates–Jensen Wound Assessment Tool (BWAT) and The Rand Social Health Battery. Results Data statistics analyzed using independent t-test showed that wound degree had no significant relationship with social interaction (p =0.448, α =0.05). However, this study concludes that the related factor of social interaction is odor (p =0.009), psychology (p =0.010) and stress (p =0.005). Conclusion This study recommended the importance of paying attention to the psychological comfort of physical discomfort to increase the social comfort of diabetic ulcer patients.