In the field of mobile health monitoring the current most important user groups are those aged 50 +. In our project senSAVE® we developed a user interface for monitoring vital personal parameters that is specifically adapted to the needs of this group. The group is said to show less perception and control capability and has less experience in the use of information technology. More realistically, the group of 50 + users shows more diversity in their cognitive, sensory and motor skills than younger people. User interfaces for elderly people should therefore be designed for different capabilities and needs. For a mobile health monitoring system three design types were developed and evaluated in this study: three basic interfaces, two professional interfaces and an interface in between as a compromise of the two former types. Beyond monitoring the vital parameters of the user during mobile phases a stationary module for the inspection of aggregated data was included on a standard TV set together with a remote control device. The paper describes the user interface design and a comparative evaluation of the interfaces during and after the development, i.e. formative and summative evaluation. It also describes first user feedback about the stationary component.