Thermal and strain management is required for a considerate lithium-ion battery management system (BMS) to depress the operating temperature and strain. In this paper, non-destructive temperature equipment and strain gauges are used simultaneously to monitor the temperature and strain of 18650 lithium-ion battery pack with a heat pipe cooling device (HPCD) which is used to depress temperature. At the steady-state and dynamic-state discharge processes, the temperature of pack is dramatically different with cooling device or not, and the optimal operating temperature is kept when HPCD is embedded in the center of pack with forced convection. The strain decreases in discharge progress after the pack is equipped with HPCD and has the same trend of temperature change in charge-discharge cycle process. The battery management system of temperature and strain is also effective during multiple charge-discharge processes. Furthermore, this system has the superiority of low power consumption.