Metal–Organic Frameworks (MOFs) are counterpart of many porous entities and are pertinent materials for future needs in almost in every sphere of life. The augmentation in the study of MOFs elicits significant information related to many potential applications. There are many systematic and facile synthetic routes such as hydro/solvothermal technique, microwave, electrochemical and mechanochemical etc. The experimentation, approximation by trial-and-error approaches is still applicable for the preparation of metal organic framework materials. The strategies used in the design of MOFs play crucial role in point of view of the desired application. This review compiles and describes varied eccentric traits of MOFs, synthetic approaches, and mechanisms corresponding to applications in the comprehensible way. The remarkable achievements by researchers in the field of MOFs for targeted applications and the way forward to take up the measures to design and develop MOFs are also addressed.