NMR spectroscopy continues to evolve, and publications in 2007 provide an eclectic collection of applications, advances and incremental improvements, with solid-state MAS investigations of bio-systems making a significant contribution. Higher magnetic field spectrometers (or more accurately, some funding to enable the purchase of) have allowed “difficult-to-measure” nuclei such as 17O, for example, to become more mainstream. Fast 2D methods, covariance analysis and multiple acquisition methods allow chemists rapid access to detailed analyses. A 7D protein NMR data set can be recorded in 50 hours. The TROSY experiment has been used extensively to obtain dynamics information from large proteins. The accuracy of calculated and predicted NMR parameters (δ, J, D, CSA, Q) has improved and is becoming more accessible to the bench chemist, such that many solid-state NMR papers contain considerable computational and modelling data. I am indebted to the great and the good whose work has been reported here, all credit is theirs; errors, omissions and blame are all mine.
