A gas–liquid interfacial synthesis approach has been developed to prepare SnO2/graphene nanocomposite. The as-prepared nanocomposite was characterized by X-ray diffraction, field emission scanning electron microscopy, transmission electron microscopy, and Brunauer–Emmett–Teller measurements. Field emission scanning electron microscopy and transmission electron microscopy observation revealed the homogeneous distribution of SnO2 nanoparticles (2–6nm in size) on graphene matrix. The electrochemical performances were evaluated by using coin-type cells versus metallic lithium. The SnO2/graphene nanocomposite prepared by the gas–liquid interface reaction exhibits a high reversible specific capacity of 1304mAhg−1 at a current density of 100mAg−1 and excellent rate capability, even at a high current density of 1000mAg−1, the reversible capacity was still as high as 748mAhg−1. The electrochemical test results show that the SnO2/graphene nanocomposite prepared by the gas–liquid interfacial synthesis approach is a promising anode material for lithium-ion batteries.