Using the Child Behavior Checklist, the behavior of 16 children with cryptogenic localization-related epilepsy was assessed at first admission to our epilepsy center, and approximately 2 years later. Behavior improved substantially from t1 (first assessment, when patients were admitted to our center) to t2 (reassessment after approximately 2 years) on almost all subscales of the Child Behavior Checklist. At t2, all subscales scored within normal range. Furthermore, seizure frequency improved considerably in the 2 years between assessments. After a period of approximately 2 years, normalization of behavior in children with cryptogenic localization-related epilepsy occurred.