A model based on empirical relationships is used to study frequency and magnitude of the sediment resuspension by wind-induced waves. The model has been developed for Laguna Galarza, a mesotrophic round-shaped shallow lake located in Esteros del Iberá wetland. Given the logistic and accessibility difficulties of this macrosystem, the installation of automated field stations facilitated continuous data acquisition. Using the wave theory, a daily spatial model of resuspension was built from simultaneous time series of hourly measurements of infrared nephelometric turbidity, wind speed and wind direction. The model was used to predict total suspended solids in another lake of the wetland (Laguna Iberá) showing a good agreement with observed field values, even although Laguna Iberá has a more irregular contour and a eutrophic state. Finally, we apply the model to discuss the ecological impacts of resuspension on the distribution of the littoral communities and to characterize the composition of the particulate suspended matter of the limnetic ecosystem. The model was useful to simulate the possible implications of the recent alterations of the wetland water level on the resuspension regime of the open water bodies.