A 1D electrochemical-thermal model is developed to characterise the behaviour of a 53 Ah large format pouch cell with LiNixMnyCo1-x-yO2 (NMC) chemistry over a wide range of operating conditions, including: continuous charge (0.5C-2C), continuous discharge (0.5C-5C) and operation of the battery within an electric vehicle (EV) over an urban drive-cycle (WLTP Class 3) and for a high performance EV being driven under track racing conditions. The 1D model of one electrode pair is combined with a 3D thermal model of a cell to capture the temperature distribution at the cell scale. Performance of the model is validated for an ambient temperature range of 5 °C –45 °C . Results highlight that battery performance is highly dependent on ambient temperature. By decreasing the ambient temperature from 45 °C to 5 °C, the available energy drops by 17.1% and 7.8% under 0.5C and 5C discharge respectively. Moreover, the corresponding power loss is found to be: 5.23% under the race cycle as compared with 7.57% under the WLTP drive cycle. Formulation of the model is supported by a comprehensive set of experiments, for quantifying key parameters and for model validation. The full parameter-set for the model is provided ensuring the model is a valuable resource to underpin further research.