Titanium dioxide nanotubes (TNTs) have attracted a considerable amount of attention over the past several decades. TNTs in the form of high-quality nanotube bundled structures may enhance the performance of several applications and may be suitable in various field; fuel cells, photocatalytic systems, energy storage devices, sensors and environmental analysis systems. The unique properties of TNTs make it able to be use in those field with minimum problems encountered. The fabrication of TNTs was discussed briefly with its advantages and disadvantages stated. Thus, this study investigates the use of TNTs in several promising applications and describes the current problems together with future potential developments in related fields.