Monitoring of blood glucose levels is important to persons with diabetes or pre-diabetic, abnormal glucose indications. Such individuals must determine when insulin is needed to reduce glucose levels in their bodies, or when additional glucose must be administered to raise levels. A conventional technique used by many diabetics to personally monitor their glucose level includes the periodic drawing of blood, the application of blood to a test strip, and determination of blood glucose level using calorimetric, electrochemical, or photometric detection. This technique does not permit continuous or automatic monitoring of levels in the body, but typically must be performed manually, and on a periodic basis. Unfortunately, checking consistency varies widely among individuals, where wide variation of high or low levels of glucose or other analytes may have detrimental effects. The ongoing capture of data through continuous and/or automatic in vivo monitoring of analyte levels, and its inclusion with a user-friendly computer interface, is now possible using a subcutaneous implanted sensor. Such devices are small and comfortable when used, allowing a wide range of life activities. In this technology review we propose one promising model using a combination of emerging, systems-based technologies in non-invasive analyte monitoring, as integrated within household-based health monitoring using home appliances.