Publisher Summary The chapter discusses the formation, mission, and operation of the Ethics Advisory Board (EAB) established by PharmaSNPs to address its ethical issues. For PharmaSNPs to provide this set of tools and services, it had to perform some preliminary SNP collection and diagnostic work. This process involved collecting DNA samples for SNP detection from an ethnically and geographically diverse panel of individuals. PharmaSNPs' EAB was set up to be true to its title and strictly advisory, with a focus on the area of research and clinical practice, not on ethical questions related strictly to business activities. The company could disagree and choose not to move ahead with the EAB's recommendations. This helped shield the EAB members from liability, both for the advice they gave and the decisions the company ultimately took, making it much easier to attract members. The Chair drafted a constitution for the EAB. It was reviewed by another PharmaSNPs' ethics consultant, whom the Chair invited to join the EAB to tap her wealth of international and legal experience.