Three-leg inverters for photovoltaic systems have many disadvantages, especially when the load is unbalanced. These disadvantages are, for example, small utilization of the DC link voltage, the dependency of the modulation factor of the load current and the superposition of a DC component with the output AC voltage. A solution for these problems is the 4-leg inverter. Most papers dealing with 4-leg inverters suggest classic controllers, such as PI controller, for the system. However, the transient performance of the closed-loop system does not become acceptable. On the other hand, adaptive control of 4-leg inverters has not yet been discussed in the literature. This paper proposes pole-placement control strategy, via state feedback, for 4-leg voltage-source inverters to adjust the transient performance of the closed-loop system. In addition, a STR (self-tuner regulator) is introduced to guarantee the adaptive performance of the controller in the presence of time-variant RL loads. Simulation results validate the theoretical results and proposed control strategy.