An initial study of a non-precious metal based bifunctional oxygen electrode for use in regenerative fuel cells with alkaline anion exchange membranes is described. Four nanometer size Cu x Mn0.9−x Co2.1O4 samples (x =0, 0.3, 0.6, and 0.9) were prepared and characterized with XRD, SEM, TEM, and cyclic voltammetry. The Cu x Mn0.9−x Co2.1O4 samples exhibited promising ORR and OER catalytic activities. The gap between ORR half wave potentials of Pt/C and Cu x Mn0.9−x Co2.1O4 in 1M KOH achieved only 50mV. The onset potentials for OER on Cu x Mn0.9−x Co2.1O4 catalysts were more than 100mV more negative than Pt/C in 1M KOH. MEA with Cu x Mn0.9−x Co2.1O4 bifunctional oxygen electrode was prepared with CCM method and applied in a laboratory scale regenerative fuel cell. In fuel cell mode the peak power density was over 80mWcm−2 and in electrolyser mode the onset voltage was about 1.55V. The fuel cell to electrolyser voltage ration at 100mAcm−2 achieved c.a. 31.87%.