PVC based membrane containing dicyclohexano-18-crown-6 (I) as active material along with sodium tetraphenyl borate (NaTPB) as an anion excluder and dibutyl phthalate as solvent mediator in the ratio 20:4:150:150 (w/w) (I–NaTPB–DBP–PVC) exhibits good properties with a Nernstian response of 29.0±1.0 mV per decade of activity and a working concentration range of 2.1×10−5–1.0×10−1 M. The working pH range of the sensor is 1.9–7.0. It exhibits a fast response time as fast as 17 s and has a lifetime of about 6 months. The proposed sensor has good selectivity for cadmium over alkali, alkaline earth, some transition and heavy metal ions. The sensor works satisfactorily in mixtures having 10% (v/v) non-aqueous content without showing any considerable change in working concentration range or slope. It has been successfully used as an indicator electrode for the potentiometric titration of Cd2+ against EDTA as well as for its determination in wastewaters.