Spherical morphology [Ni0.4Co0.2Mn0.4]3O4 materials have been synthesized by ultrasonic spray pyrolysis. The Li[Ni0.4Co0.2Mn0.4]O2 powders were prepared at various pyrolysis temperatures between 500 and 900°C. The Li[Ni0.4Co0.2Mn0.4]O2 material prepared at a pyrolysis temperature of 600°C samples are exhibited excellent electrochemical cycling performance and delivered the highest discharge capacity at over 180mAhg−1 between 2.8 and 4.4V. The structural, electrochemical, morphological property and thermal stability of the powders were characterized by X-ray diffraction (XRD), galvanostatic charge/discharge testing, scanning electron microscopy (SEM), and differential scanning calorimeter (DSC), respectively.