The utilization of a hybrid battery system (combination of different battery packs via dc/dc converter) in an electric vehicle application is discussed. It is investigated whether battery aging in an electric vehicle can be reduced by using a hybrid battery system. Cycle aging measurements of lithium-ion battery cells were performed at 23 °C against the background of the latter application. Recommendations for hybrid battery system electric vehicle operation are given. For Panasonic NCR 18650 BD cylindrical high energy cells (graphite anode, Li(NiCoAl) O2 cathode), three cycle aging campaigns were conducted systematically, evaluating the impact of charging as well as discharging loads with different time scales and microcycling per driving distance. A significant impact of recuperation pulse duration on aging per driving distance could be observed, whereas varied discharge load characteristics did not vary the aging characteristics. On the basis of differential open circuit voltage analysis, possible degradation mechanisms are discussed. The main driver of capacity loss and resistance increase in cycle aging campaigns with real world driving cycles appears to be the loss of cyclable lithium. Within the operating conditions investigated here, anode aging is intensified with increasing recuperation pulse duration. Another cycle aging campaign with symmetric current rate of 10C for a prismatic high power battery cell (Li4Ti5O12 anode, metal oxide cathode) yielded excellent cycle performance of this cell.