Many researches highlight the relationship between fatigue and performance. Sleep deprivation consists in keeping the participant awake for minimum sixteen hours. The study is focused to on highlighting the influence of 24hours of sleep deprivation on short term memory and attention to details tasks. The participants were 74 young students, aged between 19 and 24 years old (m= 21.2; S.D.=1.63). The instrument: tachistoscope test (TAVTMB) (Schuhfried, 2006). By applying Man Whitney nonparametric test for independent groups, the research hypothesis has been confirmed (p<0.05). The findings provide psychological evidence-based data confirming the assumed hypothesis.