Herein, we design hybrid nanostructured microporous carbon-mesoporous carbon doped titanium dioxide/sulfur composite (MC-Meso C-doped TiO2/S) as a positive electrode material for lithium-sulfur batteries. The hybrid MC-Meso C-doped TiO2 host material is produced by a low-cost, hydrothermal and annealing process. The resulting conductive material shows dual microporous and mesoporous behavior which enhances the effective trapping of sulfur and polysulfides. The hybrid MC-Meso C-doped TiO2/S composite material possesses rutile TiO2 nanotube structure with successful carbon doping while sulfur is uniformly distributed in the hybrid MC-Meso C-doped TiO2 composite materials after the melt-infusion process. The electrochemical measurement of the hybrid material also shows improved cycle stability and rate performance with high sulfur loading (61.04%). The material delivers an initial discharge capacity of 802 mAh g−1 and maintains it at 578 mAh g−1 with a columbic efficiency greater than 97.1% after 140 cycles at 0.1 C. This improvement is thought to be attributed to the unique hybrid nanostructure of the MC-Meso C-doped TiO2 host and the good dispersion of sulfur in the narrow pores of the MC spheres and the mesoporous C-doped TiO2 support.