Hami in Xinjiang is one of China's comprehensive energy bases. However, in recent years, this region has been plagued by some problems affecting the development of the energy industry. For example, wind and solar power generation is facing serious curtailment. The region is also characterized by significant pollution because of the coal chemical industry. Hydrogen energy storage has wide application potential and has become a hot research topic in the field. Building a hybrid pluripotent coupling system with wind power, photovoltaic (PV) power, and hydrogen energy storage for the coal chemical industry is an effective way to solve the above-mentioned problems. In this paper, a hybrid multi-energy coupling system is established, which includes a wind energy and PV complementary system, power distribution system, hydrogen energy storage system, gas distribution system, coal chemical industry system, waste heat utilization system, and methanol, O2, and H2 hybrid power generation system. Based on the wind and solar energy resources in Hami, the optimization model of the wind and solar power system is established. The hydrogen energy storage system model is obtained using energetic macroscopic representation. Finally, the economic performance of the system is studied. Results show that the integrated system of wind power, solar power, PV power, and hydrogen energy storage for the coal chemical industry can meet the current situation of China's energy development. The system can also make full use of new energy sources, such as wind power, PV energy, and other forms of energy, thereby reducing the environmental pollution caused by the coal chemical industry and minimizing the industry's ecological impact. In addition, hydrogen energy storage can also be applied to the new energy automotive industry. The findings of this study are of great strategic significance to China's energy system.