This work introduces an effective, inexpensive and large-scale production route to the fabrication of a novel honeycomb-spherical Co3O4-TiO2 nanocomposite anode material for use in rechargeable lithium ion batteries. The microstructure and phase composition of the Co3O4-TiO2 product were characterized systematically. The Co3O4-TiO2 nanocomposite electrode yielded fairly high reversible capacity of ∼1000mAh/g at 200mA/g after 100 cycles. Moreover, the electrode exhibited extraordinary rate ability and could regain its original specific capaities as reversing to the low current densities. Meanwhile, when being applied as anode material in full cells, it still achieved remarkably improved electrochemical performance compared with traditional graphite material. Noticeably, in-situ XRD measurement verified the conversion mechanism for the Co3O4-TiO2 electrode. The likely contributing factors to these outstanding electrochemical properties of the Co3O4-TiO2 nanocomposite could be related to the distinctive morphology including interlaced Co3O4 nanoflakes (NFs) and the TiO2 nanoparticles (NPs), which contains superior structural stability and allows more channels for the Li+ insertion/extraction reaction. This research shows that the as-prepared Co3O4-TiO2 nanocomposite could be suitable for use as a favorable cycle performance anode material for lithium ion batteries.