Although logistic always had an important supportive function in organizations, involving new technologies in logistics operations has changed its function to a value-added function. Nowadays, information system and technologies are such a critical component of a logistic system that information flow is considered as important as material and financial flow in logistics. In this chapter, after reviewing the role and importance of information in logistics systems, four levels of functionality in companies which are affected by logistic information systems (LIS) are described. These four levels are transaction system, management control, tactical planning, and strategic planning. Then, the three main components of LIS, i.e., input, database, and output, are explained. LIS, normally, has five modules that are clarified in this chapter. Finally, the characteristics of LIS that should be concerned in designing and evaluating are discussed. In the second part of this chapter, emerging technologies in the area of information technology are briefly discussed.