The Li4Ti5O12/Ketjen Black composites are synthesized via a simple hydrothermal method. The materials are characterized by XRD, SEM, HR-TEM, EDS, galvanostatic charge/discharge test, CV and EIS. The results indicate that Li4Ti5O12 (LTO) particles grow both in the pores and on the surface of mesoporous Ketjen Black (KB) forming open conductive frameworks and the Ketjen Black works as host forthe growth of Li4Ti5O12 primary nanoparticles. The LTO/KB electrode is fabricated without extra carbon black conductive agents and exhibits excellent electrochemical performances, especially at low temperature. The improved performances can be attributed to the presence of mesoporous Ketjen Black conductive templates with high electronic conductivity and formed 3D frameworks beneficial to the lithium ion diffusion.