Quantifying water exchange between a coastal wetland and the underlying groundwater is important for closing water, energy and chemical budgets. The coastal wetlands of the Florida Everglades (USA) are at the forefront of a large hydrologic restoration project, and understanding of groundwater/surface-water interactions is needed to comprehend the effects of the project. Four independent techniques were used to identify water exchange at varying spatial and temporal scales in Taylor Slough, Everglades National Park. The techniques included a water-budget study and measurements of hydraulic head gradients, geochemical tracers, and temperature. During the 18-month study, the four methods converged as to the timing of groundwater discharge, typically between June and September, contemporaneous with the wet season and increasing surface-water levels. These results were unexpected, as groundwater discharge was predicted to be greatest when surface-water levels were low, typically during the dry season. Either a time lag of 1–5 months in the response of groundwater discharge to low surface-water levels or precipitation-induced groundwater discharge may explain the results. Groundwater discharge was a significant contributor (27 %) to the surface water in Taylor Slough with greater rates of discharge observed towards the coastline in response to seawater intrusion.