This paper develops a general model with which to evaluate flow uniformity and pressure drop within interdigitated-channel structures, especially in the context of redox flow batteries. The governing equations are cast in dimensionless variables, leading to a set of characteristic dimensionless parameter groups. The systems of governing equations are solved computationally, with the results presented graphically. Because the results are general, the underlying model itself is not needed to apply the quantitative design guidelines. However, the paper presents and discusses all the information required to recreate the model as needed.