A simple and versatile method for preparation of novel manganese 2,5-thiophene dicarboxylate microspheres is developed via a surfactant-assisted solvo-thermal route, which are found to be a new high-energy anode material for lithium-ion batteries. It shows better cycling performance and higher discharge capacity than its counterpart of irregular shapes. A reversible capacity was achieved as high as 645.7mAhg−1 after 250 cycles at a current density of 400mAg−1. Furthermore, the coulombic efficiency can be close to 100% even after 650 charge-discharge cycles at a current density of 500mAg−1.