This manuscript discuss about the various DC-DC converter configurations with high voltage conversion ratio utilized in DC micro-grid structures. The presented DC-DC converter topologies play a major role globally in the power generation sector including micro-grid, because of its decreased number of semiconductor devices, maximum conversion efficiency, small in size and cost of manufacturing is less. In this manuscript the DC-DC converter are categorized in to isolated and Non-isolated topologies. The first group topography works with the presence of transformer and the second group works without the transformer. These converters are capable to provide the various stages of output range. Researchers utilize these converters in the area of renewable energy generation, electric vehicle, micro sources, charge pumping applications etc. Hence they also work to improve the efficiency and reliability with reduction in components numbers and economical aspect. In this manuscript, the various topography of DC-DC converter topologies utilized in micro-grid are reviewed and comparison is made based on voltage conversion ratio, duty ratio, efficiency along with the basic operating principle. This review also reveals the research gaps, current trends, and challenges in the last part.