The hierarchical porous ZnMn2O4 microsphere is successfully synthesized by a facile ultrasonic spray pyrolysis technology combined with the thermal annealing treatment in air. The porous microspheres are built from interconnected porous nanosheets which are composed of numerous nanoparticles with size of approximately 15nm. This unique structure could not only facilitate the transfer of ions and electrons, but also accommodate large volume expansion and contraction so that it shows excellent electrochemical performance. When used as anode materials for lithium ion batteries (LIBs), the ZnMn2O4 porous microspheres exhibited a discharge capacity of 1044mAhg−1 after 300 cycles at a current of 500mAg−1 and superior rate capability (859mAhg−1 at 2000mAg−1). The highly porous structure with nanosheet networks composed of nanoparticles is responsible for the enhanced performance.