Psychomotor agitation is a series of unintentional and
purposeless motions that stem from mental tension and anxiety of
an individual. This includes pacing around a room, wringing
one's hands, pulling off clothing and putting it back on and
other similar actions. In more severe cases, the motions may
become harmful to the individual, such as ripping, tearing or
chewing at the skin around one's fingernails or lips to the
point of bleeding. Psychomotor agitation is a symptom typically
found in major depressive disorder or obsessive-compulsive
disorder, and sometimes the manic phase in bipolar disorder,
although it can also be a result of an excess intake of
stimulants. The middle aged and the elderly are more at risk to
express this condition. Both intramuscular midazolam and
droperidol decrease the duration of agitation. See also  - ^
Isbister GK, Calver LA, Page CB, Stokes B, Bryant JL, Downes MA
(October 2010). "Randomized controlled trial of intramuscular
droperidol versus midazolam for violence and acute b