Pharmacogenetics is the study of genetic causes of individual
variations in drug response; pharmacogenomics more broadly
involves genome-wide analysis of the genetic determinants of
drug efficacy and toxicity. Primary candidate genes of interest
include those encoding for drug receptors, metabolizing enzymes,
and transporters. However, selection of optimal drug therapy may
also involve disease susceptibility genes indirectly affecting
drug response. Moreover, pharmacogenomics includes the
identification of suitable targets for drug discovery and
development. - Provide a forum for information exchange on
topical developments in pharmacogenetics and pharmacogenomics
using an interactive Web page designed for the focus group
(accessible to all AAPS members). - Generate yearly theme issues
in pharmacogenetics-pharmacogenomics in The AAPS Journal. -
Establish a virtual journal in pharmacogenetics-pharmacogenomics
with links to relevant articles in all life sciences journals. -
Organize symposia, workshops, roundta