McCune Albright Syndrome National Organization for Rare
Disorders, Inc. It is possible that the main title of the report
McCune Albright Syndrome is not the name you expected. Please
check the synonyms listing to find the alternate name(s) and
disorder subdivision(s) covered by this report. - Albright
Syndrome - Osteitis Fibrosa Disseminata - Polyostotic, Fibrous
Dysplasia - Precocious Puberty with Polyostotic Fibrosis and
Abnormal Pigmentation McCune-Albright Syndrome (MAS) is a rare
multisystem disorder characterized by (1) replacement of normal
bone tissue with areas of abnormal fibrous growth (fibrous
dysplasia); (2) patches of abnormal skin pigmentation (i.e.,
areas of light-brown skin [cafe-au-lait spots] with jagged
borders); abnormalities in the glands that regulate the body's
rate of growth, its sexual development, and certain other
metabolic functions (multiple endocrine dysfunction). Depending
on the number and location of the skeletal abnormalities,
mobility may be impaired, as well as vision and/