A rash is a rash is a rash, right? Not quite! The target-shaped
spots of erythema multiforme may be unlike any other rash you've
ever seen. About Erythema Multiforme Erythema multiforme is a
hypersensitive reaction to an infection or, in some cases, a
medication. This reaction causes red, target-shaped or "bulls-
eye" patches or sores on the skin. The rash usually starts off
looking like pink or red blotches that develop over a few days
into round shapes that look like targets (with red, pink, and
pale rings). They sometimes have blisters or scabs in the
center. The rash usually begins on the arms, hands, legs, and
feet, but you might also find it on the face, neck, and body. It
also can affect the lips and inside the mouth. One of the
characteristics of an erythema multiforme rash is that it
develops on both sides of the body. So a kid who gets it on one
leg will probably get it on the other leg too. Kids will
typically complain that the rash itches and may even burn. As
the rash goes away, it may turn a brow