Hand-Foot Syndrome (Palmar-Plantar Erythrodysesthesia) Hand-foot
syndrome is a side effect of some chemotherapy drugs that
results when a small amount of drug leaks out of the blood
vessels, damaging tissues. This tends to happen in the hands and
the feet because of the increased friction and heat that your
extremities are exposed to through daily activities. Symptoms
can be prevented by avoiding friction and heat. Treatment
consists of reducing or stopping treatment with the drug that
caused the syndrome. You may be able to prevent symptoms by
avoiding friction or heat. - What is hand-foot syndrome? - Which
drugs cause hand-foot syndrome? - What are the symptoms of hand-
foot syndrome? - How can hand-foot syndrome be prevented? - How
is hand-foot syndrome treated? - What else can I do? What is
hand-foot syndrome? Hand-foot syndrome is a side effect of some
chemotherapy drugs that results when a small amount of drug
leaks out of the smallest blood vessels in the palms of the
hands and soles of the feet. The am