Human T-lymphotropic virus 1 |Human T-lymphotropic virus|
|Group:||Group VI (ssRNA-RT)| |Species:||Simian T-lymphotropic
virus| Human T-lymphotropic virus Human T-cell Lymphotropic
virus or Human T-lymphotropic virus Type 1 (HTLV-I), also called
the Adult T-cell lymphoma virus type 1 or (Adult T-cell leukemia
lymphoma ATLL) a virus that has been implicated in several kinds
of diseases including HTLV-I-associated myelopathy,
Strongyloides stercoralis hyper-infection, and a virus cancer
link for leukemia (see adult T-cell leukemia/lymphoma). Between
one in twenty and one in twenty-five infected persons are
thought to develop cancer as a result of the virus. HTLV was
discovered in 1977 in Japan. The virus was first isolated by
Bernard Poiesz and Francis Ruscetti and their co-workers in the
laboratory of Robert C. Gallo at the NCI. It was the first
identified human retrovirus. Clinical forms of ATLL 1- Acute :
Leukemic picture, organomegally, high lactate dehydrogenase
(LDH) and often hypercalcaemia. 2- Chronic: