Soft drinks consumption and nonalcoholic fatty liver disease.
Nonalcoholic fatty liver disease (NAFLD) is a common clinical
condition which is associated with metabolic syndrome in 70% of
cases. Inappropriate dietary fat intake, excessive intake of
soft drinks, insulin resistance and increased oxidative stress
combine to increase free fatty acid delivery to the liver, and
increased hepatic triglyceride accumulation contributes to fatty
liver. Regular soft drinks have high fructose corn syrup which
contains basic sugar building blocks, fructose 55% and glucose
45%. Soft drinks are the leading source of added sugar
worldwide, and have been linked to obesity, diabetes, and
metabolic syndrome. The consumption of soft drinks can increase
the prevalence of NAFLD independently of metabolic syndrome.
During regular soft drinks consumption, fat accumulates in the
liver by the primary effect of fructose which increases
lipogenesis, and in the case of diet soft drinks, by the
additional contribution of aspartame sweeten