What is multidrug-resistant tuberculosis and how do we control
it? Q: What is multidrug-resistant tuberculosis and how do we
control it? A: The bacteria that cause tuberculosis (TB) can
develop resistance to the antimicrobial drugs used to cure the
disease. Multidrug-resistant tuberculosis (MDR-TB) is TB that
does not respond to at least isoniazid and rifampicin, the two
most powerful antituberculosis drugs. Every year, more MDR-TB
cases are being reported. The primary cause of multidrug
resistance is mismanagement of TB treatment. Most people with
tuberculosis are cured by a strictly followed, six-month drug
regimen that is provided to patients with support and
supervision. Inappropriate or incorrect use of antimicrobial
drugs, or use of ineffective formulations of drugs, can cause
drug resistance. Strong and enforced regulations to ensure
acceptable, effective tuberculosis treatment can help control
MDR-TB. In some countries, it is becoming increasingly difficult
to treat MDR-TB. Treatment options are limit