First-Generation Antipsychotics for Treating Schizophrenia These
medicines are available as tablets, a concentrated liquid, or an
injection (shot). Long-acting formulas that are given every 2 to
4 weeks are available for fluphenazine and haloperidol. How It
Works Experts don't know exactly how these antipsychotic
medicines work. They think these medicines work because of how
they affect brain chemicals (neurotransmitters). They usually
are started at low doses to avoid side effects. Why It Is Used
First-generation antipsychotics are used to reduce anxiety and
agitation that often happen in schizophrenia. They can also
reduce problems with thinking or remembering (cognitive
impairment) and reduce or control delusions and hallucinations
(psychosis). How Well It Works First-generation antipsychotics
can reduce or control psychosis and improve thinking, mood, and
behavior. These medicines may help you return to a more normal
daily life while living with schizophrenia. First-generation
antipsychotics may work diff