ClairScope™ consists of an atmospheric scanning electron
microscope (ASEM) and an optical microscope positioned on top.
The ASEM is isolated from the SEM with a thin film installed at
the top end of the inverted SEM. The thin film, designed to
transmit an electron beam while blocking air, separates the
sample in atmosphere from the vacuum in the SEM. The electron
beam is projected from below to the sample placed on the thin
film for high resolution imaging of the sample in atmosphere.
The same area of view of the sample can also be imaged in the
optical microscope on top. The thin film is configured in a dish
(thin film dish), which can be used for cell culture in a
culture chamber. SEM imaging in complete atmospheric pressure
The sample is held in complete atmospheric pressure, enabling
dynamic observation of physical and chemical reactions in
liquids and gases. Lengthy preliminary treatment of biological
samples, including dehydration and drying, is no longer
necessary, resulting in high throughput imaging.