Lower extremity peripheral arterial disease (PAD) is a marker of
widespread atherosclerosis. Individuals with PAD, most of whom
do not show typical PAD symptoms ('asymptomatic' patients), are
at increased risk of cardiovascular ischaemic events. American
College of Cardiology/American Heart Association guidelines
recommend that individuals with asymptomatic lower extremity PAD
should be identified by measurement of ankle-brachial index
(ABI). However, despite its associated risk, PAD remains under-
recognised by clinicians and the general population and office-
based ABI detection is still poorly-known and under-used in
clinical practice. The Prevalence of peripheral Arterial disease
in patients with a non-high cardiovascular disease risk, with No
overt vascular Diseases nOR diAbetes mellitus (PANDORA) study
has a primary aim of assessing the prevalence of lower extremity
PAD through ABI measurement, in patients at non-high
cardiovascular risk, with no overt cardiovascular diseases
(including symptomatic PAD),