Menkes syndrome is an inherited genetic disorder due to an
abnormal gene, ATP7A. Menkes syndrome causes impaired copper
absorption. This results in arterial changes and deterioration
of the brain. Menkes syndrome is rare. It occurs in 1 out of
every 50,000-100,000 births. It affects primarily males. Most
children born with Menkes syndrome have a life expectancy of 3
to 5 years. Copper proteins are necessary for the body to build
bone, nerves, and other tissue. Babies with Menkes syndrome have
a genetic disorder that prevents the absorption of copper from
the intestines and causes it to build up in excess amounts in
the kidney, while remaining deficient in the liver and brain.
This causes changes in the hair, brain, bones, liver, and
arteries. A risk factor is something that increases your chance
of getting a disease or condition. Risk factors for Menkes
syndrome include: Children with Menkes are often born
prematurely. Symptoms usually begin to show within three months
after birth and may include: Babies with