Fructose does not make individuals feel as full as glucose and
may cause them to eat more, according to a study published in
the January 2, 2013, issue of the Journal of the American
Medical Association. Researchers at Yale University found that
fructose and glucose have different effects on the brain. Twenty
normal-weight young adults were given either a pure fructose or
pure glucose drink. Using a magnetic resonance imaging
technique, the researchers measured blood flow in the
hypothalamic region of the brain before and after participants
consumed the sugar drinks. The researchers found that
participants who consumed glucose had high levels of the
hormones that cause feelings of satiety. However, those who
consumed fructose had a smaller increase of the same hormones.
The researchers suggest that the findings support the idea that
fructose affects appetite regulation and leads to overeating.
Although fructose is found naturally in fruit, the researchers
believe that fructose that is added to many processed