Highly fatal viral disease of CNS affect all warm blooded animal
producing abnormal behavior, sign of mania and paralysis of most
animals it afflicts. Rhabdoviruses (Rhabdos = rod). Lyssavirus
(Lyssa madness) one of the larger virus. a RNA neurotropic virus
Bullet shape 70 170 nm Have bilayer envelope. Repeated freezing
and thawing. 20% fresh soap solution. 2 forms of the virus are
exist.. Refers to strains adapted to secondary host for
!aoratory iurk and vaccine produobon-replicat well in vero cells
(green african monkey kidney cels, Baby hamster kidney (Bl-K
21), chick embryo fibrobiasts. Refers to strains isolated from
infectea animals replicate well in suckling nouso and suckNrtg
ham3te i1n NB: Rhabdciruses causes: Vesicular stomatit Bovine
ephemeral fever Bovine ephernera lever ike dheas When irritation
occur it will be followed by paralysis as the stimuiated n-cells
are subseuent uetiuycd but gradually ascending paralysis t
aiters followed by quite severe sign of mania .Nhich oersist
unti d: The chv inf