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searches - My saved topics - My newsletter Acute renal failure
Acute renal failure (ARF), also known as acute kidney failure or
acute kidney injury, is a rapid loss of renal function due to
damage to the kidneys, resulting in retention of nitrogenous
(urea and creatinine) and non-nitrogenous waste products that
are normally excreted by the kidney. Depending on the severity
and duration of the renal dysfunction, this accumulation is
accompanied by metabolic disturbances, such as metabolic
acidosis (acidification of the blood) and hyperkalaemia
(elevated potassium levels), changes in body fluid balance, and
effects on many other organ systems. It can be characterised by
oliguria or anuria (decrease or cessation of urine production),
although nonoliguric ARF may occur.