|syndrome, klinefelter||medical dictionary| The most common
single cause of hypogonadism (underfunction of the gonads) and
infertility in men, klinefelter syndrome is due to a chromosome
abnormality with xxy (plus additional x or y chromosomes). It
affects about 1 in 500 males and results in small testes
(hypogenitalism), underproduction of testosterone and
infertility (hypogonadism), and a long-limbed, long-trunked,
relatively tall, slim build. Klinefelter boys tend to have
learning and/or behavioural problems. at adolescence there is
little growth of facial hair and a third of boys develop
gynaecomastia (enlargement of the male breast). Named for the
physician harry klinefelter who with e.c. Reifenstein, jr. And
fuller albright (the founder of modern endocrinology) described
the condition in 1942 long before its chromosomal basis became
known. (12 Dec 1998) |Bookmark with:||word visualiser||Go and
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