Gingivitis Survives By Manipulating Immune System New research
published in the Journal of Leukocyte Biology suggests that
Porphyromonas gingivalis causes excess IL-10 production, which
inhibits the immune cells interferon gamma leading to infection
A new research report published in the Journal of Leukocyte
Biology shows how the bacteria known for causing gum
disease–Porphyromonas gingivalis–manipulates the body’s immune
system to disable normal processes that would otherwise destroy
it. Specifically, the report shows that this pathogen prompts
the production of the anti-inflammatory molecule Interleukin-10
(IL-10). This, in turn, inhibits the function of T-cells, which
would otherwise help to protect the host from this particular
microbial infection. “Since greater than 50 percent of the U.S.
population over 50 years-of-age develop adult periodontal
disease, we hope that the results of our study will ultimately
help in the development of novel treatments that could prevent
or ameliorate the chronic infectio