Multiple endocrine neoplasia (MEN) I Multiple endocrine
neoplasia (MEN) type I is an inherited disorder in which one or
more of the endocrine glands are overactive or form a tumor.
Endocrine glands most commonly involved include: Wermer
syndrome; MEN I Causes, incidence, and risk factors MEN I is
caused by a defect in a gene that carries the code for a protein
called menin. The condition causes tumors of various glands to
appear in the same person, but not necessarily at the same time.
The disorder may occur at any age, and it affects men and women
equally. A family history of this disorder raises your risk.
Symptoms vary from person to person, and depend on which gland
is involved. They may include: - Abdominal pain - Black, tarry
stools - Bloated feeling after meals - Burning, aching, or
hunger discomfort in the upper abdomen or lower chest that is
relieved by antacids, milk, or food - Decreased sexual interest
- Lack of menstrual periods, infertility, or failure to produce
breast milk (in women) - Loss of