What is the official name of the RDH12 gene? The official name
of this gene is “retinol dehydrogenase 12 (all-
trans/9-cis/11-cis).” RDH12 is the gene's official symbol. The
RDH12 gene is also known by other names, listed below. Read more
about gene names and symbols on the About page. What is the
normal function of the RDH12 gene? - From Entrez Gene: The
protein encoded by this gene is an NADPH-dependent retinal
reductase whose highest activity is toward 9-cis and all-trans-
retinol. The encoded enzyme also plays a role in the metabolism
of short-chain aldehydes but does not exhibit steroid
dehydrogenase activity. Defects in this gene are a cause of
Leber congenital amaurosis type 3 (LCA3). [provided by RefSeq,
Jul 2008] - From UniProt: Exhibits an oxidoreductive catalytic
activity towards retinoids. Most efficient as an NADPH-dependent
retinal reductase. Displays high activity toward 9-cis and all-
trans-retinol. Also involved in the metabolism of short-chain
aldehydes. No steroid dehydrogenase activity detect