Interferon type I Human type I interferons comprise a vast and
growing group of IFN proteins. Mammalian types  The IFN-α
proteins are produced by leukocytes. They are mainly involved in
innate immune response against viral infection. They come in 13
subtypes that are called IFNA1, IFNA2, IFNA4, IFNA5, IFNA6,
IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21.
These genes for these IFN-α molecules are found together in a
cluster on chromosome 9. IFN-α is also made synthetically as
medication. Types are: The IFN-β proteins are produced in large
quantities by fibroblasts. They have antiviral activity which is
mainly involved in innate immune response. Two types of IFN-β
have been described, IFN-β1 (IFNB1) and IFN-β3 (IFNB3) (a gene
designated IFN-β2 is actually IL-6). IFN-β1 is used as a
treatment for multiple sclerosis as it reduces the relapse rate.
IFN-ε, –κ, -τ, -δ, and –ζ  IFN-ε, –κ, -τ, and –ζ appear, at this
time, to come in a single isoform in humans, IFNK. Only
ruminants encode IFN-τ, a varian