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| - "Charcot joint disease" redirects here. For the nerve
disease, see Charcot-Marie-Tooth disease. Neuropathic
arthropathy (or neuropathic osteoarthropathy), also known as
Charcot joint (often "Charcot foot"), refers to progressive
degeneration of a weight bearing joint, a process marked by bony
destruction, bone resorption, and eventual deformity. Onset is
usually insidious. If this pathological process continues
unchecked, it could result in joint deformity, ulceration and/or
superinfection, loss of function, and in the worst case
scenario: amputation or death. Early identification of joint
changes is the best way to limit morbidity. - Diabetes mellitus
neuropathy (the most common in the U.S. today, resulting in
destruction of foot and ankle joints), with Charcot joints in
1/600-700 diabetics. Related to long-term poor glucose control.
- Alcoholic neuropathy - Cerebral palsy - Syphili