Liver fluke infection is a major health concern in Southeast
Asia as well as Eastern Europe. The trematode culprit of
opisthorchiasis is consumed when people eat raw or uncooked
fish; ingestion of metacercariae (pictured on the cover) results
in infection. In a Feature review by Sripa et al. on pp.
395–407, bile duct cancer caused by Opisthorchis viverrini is
addressed, including the pathogenesis of opisthorchiasis and the
hope that recent post-genomic advances will aid in controlling
this deadly cancer. Photo: courtesy of Banchob Sripa.