Update in Diagnosis and Management This slide depicts the way
that genes and environment both contribute to kidney stone
disease. Important environmental factors include causes of
insensible fluid loss, as well as the composition of the diet.
How dietary components are absorbed and then excreted by the
kidneys can be influenced by genetics. These processes in turn
determine the overall urinary supersaturation. Other genetic
factors likely influence how this supersaturation translates
into kidney stone growth, such as the functional capacity of
urinary inhibitors. Genetics and Environment Jump to section: -
Kidney Stones - Why do Kidney Stones Form? - Genetics and
Environment - Not All Stones are Created Equal: Stone Analysis
is Very Helpful - Laboratory Evaluation - Supersaturation Index
- Components of the Urinary Supersaturation Profile - Uses of
Urinary Supersaturation - Common Features Increase Urinary
Supersaturation in Patients with Idiopathic Calcium Oxalate
Nephrolithiasis - "Conservative" Dietary Rec