It still is a huge challenge to treat neurodegenerative diseases
such as Alzheimer, Parkinson or Huntington, which are
increasingly affecting our society as the average life-span of
our population increases. One of the main obstacles for
successful therapy of these disorders is safe and effective drug
delivery to the central nervous system. Tightly focused
femtosecond laser pulses have been used to modify transparent
dielectric materials, to form voids, and to polymerize resists
and resins for more than a decade. A high sub-100-nm spatial
resolution has now been reached making it potentially a nano-
fabrication tool. Researchers at the University of New Mexico
have demonstrated a new, simple, and facile approach to the
fabrication of various nanopatterned films composed of
nanoparticles. The findings could lead to nanoparticle sensors
for both biological and chemical species. Contouring measurement
methods are important for high quality, high speed and
productivity machining in order to achieve the high precis