From Classic Encyclopedia 1911 QUINOLINE (Benzopyridine), C 9 H
7 N, an organic base first obtained from coal-tar in 1834 by F.
Runge (Pogg. Ann.,. 18 34, 31, p. 68), and later by C. Gerhardt
by the distillation of cinchonine, quinine and other alkaloids
with caustic potash (Ann., 1842, 42, p. 310; 44, p. 279). It
also occurs with pyridine and its homologues in bone-oil. It may
be prepared by distilling cinchoninic acid with lime; by the
reduction of ortho-aminocinnamic aldehyde (A. Baeyer and V.
Drewson, Ber., 1883, 16, p. 2207); by passing the vapour of
allyl aniline over heated lead oxide; by the condensation of
ortho-aminobenzaldehyde with acetaldehyde in the presence of
aqueous. caustic soda (P. Friedlander and C. F. Gohring, 1882, 1
5, p. 2 57 2; 1883, 16, p. 1833); by the action of
orthotoluidine on glyoxal at 150° C. (V. Kulisch, Monats., 1894,
15, p. 276); by the action of phosphorus pentachloride on
hydrocarbostyril (the inner anhydride of ortho-
aminohydrocinnamic acid), the chlorinated compound fir