Research – Clinical Trials Neurointerventional Research Trials
ARUBA Study: A Randomized Multicenter Clinical Trial of Summary:
An arteriovenous malformation (AVM) is a tangled bundle of
abnormal arteries and veins that are directly connected to each
other. In general, arteries carry fresh oxygen-filled blood from
the heart and distribute it through fine and finer vessels
(arterioles and capillaries) to all parts of the body to nourish
the tissue. Veins bring the "used" blood back to the heart. In
the case of an AVM, there is an absence of capillaries and the
blood goes directly from an artery into a vein. The main risk of
an AVM in the brain is the risk of sudden bleeding if the AVM
ruptures. Symptoms might resemble a stroke but also may include
headaches or seizures. An AVM that has not bled is called an
unruptured AVM. It is not known whether it is better to use one
of the available interventional techniques to treat the AVM or
to simply follow medically. Purpose: The purpose of this study
is to determine