Long-Term Neurological Outcome of Childhood Brain Tumors Treated
by Surgery Only Reviewer: Ryan Smith, MD The Abramson Cancer
Center of the University of Pennsylvania Last Modified: May 2,
2004 Authors: Sonderkaer S, et al. Source: JCO, 21(7), 2003, pg
1347-1351 - Intracranial tumors are common in pediatric
patients, relative to other childhood malignancies - The results
have improved in the treatment of these tumors, with more
patients therefore experiencing late toxicity from treatment -
The focus of treatment-related late effects has been on
chemotherapy and radiation, with little attention paid to
patients treated with surgery alone - This study was done with
the population being children who had surgery alone (hence
benign disease or low grade tumors) to evaluate the effect of
surgery on the long term functioning of these patients Materials
and Methods - The study group consisted of 65 patients,
diagnosed and treated before the age of 15 - Evaluation included
chart review, physical examination, and neuro