Background: It is increasingly important that physicians have a
thorough understanding of the basic science of human genetics
and the ethical, legal and social implications (ELSI) associated
with genetic testing and counseling. Methods: The authors
developed a series of web-based courses for medical students on
these topics. The course modules are interactive, emphasize
clinical case studies, and can easily be incorporated into
existing medical school curricula. Results: Results of a ‘real
world’ effectiveness trial indicate that the courses have a
statistically significant effect on knowledge, attitude,
intended behavior and self-efficacy related to genetic testing
(p<0.001; N varies between 163 and 596 for each course).
Conclusions: The results indicate that this curriculum is an
effective tool for educating medical students on the ELSI
associated with genetic testing and for promoting positive
changes in students’ confidence, counseling attitudes and
behaviors.