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searches - My saved topics - My newsletter Isozymes (also known
as isoenzymes) are enzymes that differ in amino acid sequence
but catalyze the same chemical reaction. These enzymes usually
display different kinetic parameters (i.e. different KM values),
or different regulatory properties. The existence of isozymes
permits the fine-tuning of metabolism to meet the particular
needs of a given tissue or developmental stage (for example
lactate dehydrogenase (LDH)). In biochemistry, isozymes (or
isoenzymes) are isoforms (closely related variants) of enzymes.
In many cases, they are coded for by homologous genes that have
diverged over time. Although, strictly speaking, allozymes
represent enzymes from different alleles of the same gene, and
isozymes represent enzymes fro