In this paper we propose a methodology for estimation of global
disability-adjusted life years for cancer. Many epidemiological
variables are required to compute DALYs in a single country
according to the three-stage natural history model, and, given
the paucity of such data (irrespective of quality) in many
countries, the compilation of DALYs at the global level is
particularly challenging. Variables such as the proportion cured
from, or treated for different cancers, required in the
calculation of the YLDs, are unavailable in most countries,
particularly in low and middle income regions. The approach
outlined in this paper has produced a practical set of estimates
enabling cross-country comparisons of DALYs and their two
components, YLL and YLD. Such indicators – over and above
incidence, mortality and survival - provide valuable additional
information for planning and investing in cancer services within
current health systems and help establish the need for
population interventions aimed at reducing the bu