|http://ghr.nlm.nih.gov/ A service of the U.S. National Library
of Medicine®| 2q37 deletion syndrome is a condition that can
affect many parts of the body. This condition is characterized
by weak muscle tone (hypotonia) in infancy, mild to severe
intellectual disability and developmental delay, behavioral
problems, characteristic facial features, and other physical
abnormalities. Most babies with 2q37 deletion syndrome are born
with hypotonia, which usually improves with age. About 25
percent of people with this condition have autism, a
developmental condition that affects communication and social
interaction. The characteristic facial features associated with
2q37 deletion syndrome include a prominent forehead, highly
arched eyebrows, deep-set eyes, a flat nasal bridge, a thin
upper lip, and minor ear abnormalities. Other features of this
condition can include short stature, obesity, unusually short
fingers and toes (brachymetaphalangy), sparse hair, heart
defects, seizures, and an inflammatory skin disorder