Melanins and Melanosomes: Biosynthesis, Structure, Physiological
and Pathological Functions August 2011, Wiley-Blackwell This
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pricing and availability. Other Available Formats: E-book The
surface pigmentation of vertebrates is controlled by specialized
cells able to synthesize a variety of pigments collectively
known as melanins. Recent research has shown that melanins are
produced not only in the skin but also in many other sites such
as the eye, inner ear, muscles, etc., - where they are engaged
in some unanticipated roles. The details of the synthetic
pathway, the complexities of its regulation and biological
significance that have been unravelled in recent research
comprise a fascinating story and are of key importance in
understanding the nature of diseases, including malignant
melanoma one of the most rapidly spreading cancers.