Actually, Pharmaceuticals processing and production have
similarities to cook something. Some examples of that are,
processing similarities between wet granulation and Ruti or
Chapati cooking. Another example of this kind similarities are
emulsion production with curry cooking. Though pharmaceuticals
processing is similar to cooking but pharmaceuticals processing
is done in the more precise, more controlled and more systemic
ways to provide stability for prolong period. Here comes my blog
regarding the gastro retentive drug delivery system. About 40%
of the drug compounds are poorly water soluble1. This poor water
solubility results in decreased rate and extent of dissolution
and hence bioavailability. The formulation of a dosage form for
these compounds is a challenging aspect. A number of techniques
like micronization, nanonization, salt formation, complexation,
solid dispersions, and use of different polymorphic form of the
drug are being tried to improve the water solubility of drug
compound. Each techniq