Some applications in life-sciences require microfluidic devices
or flowcells to be coated with bio-molecules, such as DNA
primers, before sealing the device. A thermal sealing process
would ruin the bio-molecules and can not be used in this case.
To make sealing possible Micronit has developed a flexible
technology to make gaskets on glass. With this technology glass
or fused silica devices can be sealed at room temperature. Even
resealable devices can be created. The flowcells consists of two
glass plates with a gasket fabricated in between the
glassplates, applying slight pressure to the glass plates seals
the chamber creating a flowcell. The material used for the
gasket is chemically inert and can be used with most solvents.
The unique technology allows Micronit to customize flowcells at
a relatively low cost with short turnaround times. WIth a high
degree of freedom this technology is suitable to create almost
any design and it can easily be integreated with other
techniques suchs as glass-etching or the