Disease and phenotype gene set analysis of disease based gene
expression in mouse and human. Summary of "Disease and phenotype
gene set analysis of disease based gene expression in mouse and
human." The genetic contributions to common disease and complex
disease phenotypes are pleiotropic, multifactorial, and
combinatorial. Gene set analysis is a computational approach
used in the analysis of microarray data to rapidly query gene
combinations and multifactorial processes. Here we use novel
gene sets based on population based human genetic associations
in common human disease or experimental genetic mouse models to
analyze disease related microarray studies. We developed a web
based analysis tool which use these novel disease and phenotype
related gene sets to analyze microarray based gene expression
data. These gene sets show disease and phenotype specificity in
a species specific and cross species fashion. In this way, we
integrate population based common human disease genetics, mouse
genetically determined