Definition of Mercaptopurine Mercaptopurine: A drug that acts as
an antimetabolite, interfering with the metabolism of purine
bases and inhibiting the synthesis of DNA and RNA.
Mercaptopurine is used to treat acute lymphoblastic leukemia,
acute myeloid leukemia (AML), and polycythemia vera. It is also
used in the treatment of Crohn's disease, ulcerative colitis,
and psoriatic arthritis. Also known as 6-mercaptopurine, 6-MP,
or MP.Source: MedTerms™ Medical Dictionary Last Editorial
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