This study deals with preparation of substrates suitable for
surface-enhanced Raman spectroscopy (SERS) applications by
sputtering deposition of gold layer on the
polytetrafluorethylene (PTFE) foil. Time of sputtering was
investigated with respect to the surface properties. The ability
of PTFE-Au substrates to enhance Raman signals was investigated
by immobilization of biphenyl-4,4'-dithiol (BFD) from the
solutions with various concentrations. BFD was also used for
preparation of sandwich structures with Au or Ag nanoparticles
by two different procedures. Results showed that PTFE can be
used for fabrication of SERS active substrate with easy handle
properties at low cost. This substrate was sufficient for the
measurement of SERS spectrum of BFD even at 10-8 mol/l
concentration. Surface-enhanced Raman scattering (SERS) has
great potential as an analytical technique based on the surface
enhancement of Raman signals of the molecule situated on the
metal surface which is nowadays currently used for the detection