London, May 3 (ANI): An international team of scientists, led by
the University of Edinburgh, has identified three genes linked
to the development of Paget”s disease, a painful bone condition.
The researchers believe the genes are involved in regulating the
rate at which bone is repaired, providing an explanation of why
the disease might occur. Paget”s disease disrupts the body”s
normal process of breaking down old bone and replacing it. The
condition leads to enlarged and malformed bones and patients can
suffer from bone pain, brittle bones susceptible to fractures,
and advanced arthritis. The scientists said that identifying the
genes that predispose people to the bone disease could lead to
the development of a screening test to identify those most at
risk, and improve access to preventative treatment. The
researchers studied the genes of 1250 patients with Paget”s
disease to find the genes that could cause the condition. The
team – which included scientists from Spain, UK, New Zealand,
and Australia – foun