At a Glance Why Get Tested? To help investigate inappropriate
blood clot formation; to help determine the cause of recurrent
miscarriage; as part of an evaluation for antiphospholipid
syndrome (APS) When to Get Tested? When you have had one or more
unexplained blood clots in a vein or artery; when you have had
recurrent miscarriages, especially in the second and third
trimesters A blood sample drawn from a vein in your arm Test
Preparation Needed? The Test Sample What is being tested? This
test detects and measures one or more classes (IgG, IgM, or IgA)
of beta-2 glycoprotein 1 antibodies. Beta-2 glycoprotein 1
antibody is one of three primary antiphospholipid antibodies,
which are autoantibodies that target the body’s own lipid-
proteins (phospholipids) found in the outermost layer of cells
(cell membranes) and platelets. It is less common than the other
two, cardiolipin antibody and lupus anticoagulant.
Antiphospholipid antibodies interfere with the body’s blood
clotting process in a way that is not fully un