About Site Map Contact Us |A service of the U.S. National
Library of Medicine®| On this page: Reviewed April 2011 What is
the official name of the PML gene? The official name of this
gene is “promyelocytic leukemia.” PML is the gene's official
symbol. The PML gene is also known by other names, listed below.
Read more about gene names and symbols on the About page. What
is the normal function of the PML gene? The PML gene provides
instructions for a protein that acts as a tumor suppressor,
which means it prevents cells from growing and dividing too
rapidly or in an uncontrolled way. The PML protein is found in
distinct structures in the nucleus of a cell called PML nuclear
bodies (PML-NBs). In the PML-NBs, the PML protein interacts with
other proteins that are involved in cell growth and division
(proliferation) and self-destruction (apoptosis). The PML
protein is able to block cell proliferation and induce apoptosis
in combination with other proteins. Researchers believe that the
structure of the PML-NBs is r