1Department of Biomedical Engineering, Cornell University,
2Current Address: Mechanical Engineering Department, Dogus
University This article is a part ofJoVE General. If you think
this article would be useful for your research, please recommend
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Librarian Current Access Through Your IP Address Current Access
Through Your Registered Email Address Yalcin, H. C., Shekhar,
A., Rane, A. A., Butcher, J. T. An ex-ovo Chicken Embryo Culture
System Suitable for Imaging and Microsurgery Applications. J.
Vis. Exp. (44), e2154, doi:10.3791/2154 (2010). Understanding
the relationships between genetic and microenvironmental factors
that drive normal and malformed embryonic development is
fundamental for discovering new therapeutic strategies.
Advancements in imaging technology have enabled quantitative
investigation of the organization and maturing of the body plan,
but later stage embryonic morphogenesis is less clear. Chicken
embryos are an attractive vertebrate