Efficacy of Pantoprazole in Patients Older Than 18 Years Who
Have Symptoms of Acid Reflux (Gastroesophageal Reflux Disease)
(BY1023/M3-339) Gastroesophageal reflux disease (GERD) is a
medical condition affecting the stomach and esophagus. GERD
occurs when the lower esophageal sphincter does not close
properly and stomach contents leaks back (refluxes) into the
esophagus. GERD is one of the most common medical disorders,
with estimates of up to 50% of adults reporting symptoms related
to gastric reflux. Proton pump inhibitors (PPI) such as
pantoprazole can relieve symptoms of GERD in a large proportion
of patients. When refluxed stomach acidic content touches the
lining of the esophagus, it causes a burning sensation in the
chest or throat. This sensation is often referred to as
heartburn. Some patients have symptoms of GERD without visible
destruction of the tissue surface (no visible changes by
endoscopic examination). The aim of the study is to evaluate the
effect of pantoprazole on the complete remission o