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(includes Medi-Cal) State Agencies Directory Healthcare
Associated Infections Program Clostridium Difficile (C. Diff)
Clostridium Difficile Infection (CDI) (also known as C. is a
germ that can cause diarrhea. Most cases of C. infection (CDI)
occur in patients taking antibiotics. CDI is the most common
cause of diarrhea that occurs during or after use of
antibiotics. Infections can be mild and last only for a short
time, or can be severe and recur multiple times. The most common
symptoms of CDI are: Abdominal (belly) pain/tenderness Loss of
appetite Who is most likely to get CDI? Anyone who t