Cutaneous mast cell tumors are probably the most common
nonendocrine tumor in ferrets. These tumors can appear anywhere
on the body but typically affect the trunk and neck. The tumor
appears as a raised, irregular, and often scabbed mass. Systemic
signs are rare, but the tumors may bleed when scratched.
Treatment is by excision. Lymphoma is common in ferrets and can
affect many organ systems including the lymph nodes, spleen,
liver, heart, thymus, and kidneys. Disease of the spine and
central nervous system has also been seen. Lymphoma of young
ferrets is often rapidly progressive, whereas it is often a
chronic disease in adults. Clusters of lymphoma have been seen
in related or cohabitating ferrets, and a viral agent is
suspected in those cases. Diagnostics should include a CBC,
chemistry panel, radiographs, ultrasonography, and aspirates of
any suspected tissues. Treatment protocols for ferrets have not
been standardized but can include removal of the neoplastic
tissue if possible, chemotherapy, and/or radi