Basal cell nevus syndrome Basal cell nevus syndrome is a group
of defects, passed down through families, that involve the skin,
nervous system, eyes, endocrine glands, and bones. The condition
causes an unusual facial appearance and a higher risk of skin
cancers. Nevoid basal cell carcinoma syndrome; Gorlin syndrome
Causes, incidence, and risk factors Basal cell nevus syndrome is
a rare genetic condition. The gene linked to the syndrome is
known as PTCH ("patched"). The gene is passed down through
families as an autosomal dominant trait. That means you will get
the syndrome if either parent passes the gene down to you. The
hallmark of this disorder is the appearance of a type of skin
cancer known as basal cell carcinoma at or around puberty. -
Broad nose - Cleft palate - Heavy, protruding brow - Jaw that
sticks out (in some cases) - Wide-set eyes The condition may
affect the nervous system and lead to: The condition also leads
to bone defects, including: Signs and tests There may be a
family history of basal