What is lymphatic filariasis? Lymphatic filariasis is an
infectious, parasitic disease caused by nematodes (roundworms).
The disease is caused by the presence of thread-like worms,
called filariae, in the lymphatic vessels and lymph nodes of the
body. The lymphatic channels drain excess fluid from the body
and play a role in the infection-fighting immune system.
Lymphatic filariasis is transmitted by mosquitoes from person to
person. Infectious Disease Spotlight Lymphatic filariasis most
commonly occurs in developing countries with a tropical climate.
Wuchereria bancrofti, Brugia malayi, and Brugia timori are the
specific worms that cause the infection. The larvae enter the
body at the time of the mosquito bite and travel to the
lymphatic system, where they mature into adult worms. The adult
worms can live for years in the lymphatic system, and they
produce immature forms that circulate in the blood. Lymphatic
filariasis causes blockage of the lymphatic channels, leading to
swelling and eventual scarring of t