Definition of Change, single base Change, single base: A change
in which a single base in the DNA differs from the usual base at
that position. These single base changes are also called SNPs or
"snips." Millions of SNP's have been cataloged in the human
genome. Some SNPs such that which causes sickle cell are
responsible for disease. Other SNPs are normal variations in the
genome. Last Editorial Review: 6/14/2012 Back to MedTerms online
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