General Information About Adult Non-Hodgkin Lymphoma (NHL) The
NHLs are a heterogeneous group of lymphoproliferative
malignancies with differing patterns of behavior and responses
to treatment. Like Hodgkin lymphoma, NHL usually originates in
lymphoid tissues and can spread to other organs. NHL, however,
is much less predictable than Hodgkin lymphoma and has a far
greater predilection to disseminate to extranodal sites. The
prognosis depends on the histologic type, stage, and
treatment.Incidence and Mortality Estimated new cases and deaths
from NHL in the United States in 2013: - New cases: 69,740. -
Deaths: 19,020. NHL usually originates in lymphoid
tissues.Prognosis and Survival The NHLs can be divided into two
prognostic groups: the indolent lymphomas and the aggressive
lymphomas. Indolent NHL types have a relatively good prognosis
with a median survival as long as 10 to 20 years, but they
usually are not curable in advanced clinical stages. Early-stage
(stage I and stage II) indolent NHL can be effectivel