Signs and Symptoms Graves disease may cause a wide range of
signs and symptoms. They usually develop slowly, often beginning
as mild and going unnoticed at first, and then progressively
worsen. Different people may experience a different combination
of symptoms at various times. Graves disease can cause a
condition known as exophthalmos or Graves ophthalmopathy. With
this condition, tissue can build up behind the eyeballs and the
eyelids can retract, leading to a characteristic fixed stare and
protruding eyes. This can dry and irritate the eyes, interfere
with vision, and in severe cases can cause damage to the cornea,
the transparent covering at the front of the eye, and to the
optic nerve, the nerve that transmits light images to the brain,
resulting in vision loss. Some other signs and symptoms may
include: - Difficulty concentrating - Double vision - Eye
irritation and tearing - Frequent bowel movements - Gynecomastia
(rare) - Hand tremors - Heat sensitivity - Increased appetite -
Increased or irregular h