Granulomatous Meningoencephalomyelitis in Dogs Granulomatous
meningoencephalomyelitis (GME) is an inflammatory disease of the
central nervous system (CNS) that leads to the formation of
granuloma(s) -- a ball-like collection of immune cells formed
when the immune system tries to wall off foreign substances --
which can be localized, diffused, or involving multiple
locations, such as the brain, spinal cord and surrounding
membranes (meninges). This disease is the most well recognized
and accepted CNS inflammatory disorder in dogs. However, dogs
between the ages of 6 months and 10 years are most commonly
affected with GME. And although both sexes can be affected,
there is a slightly higher prevalence in females. Symptoms and
Types The symptoms depend on the form of disease and its
location. For example, the ocular form of GME will affect the
eye region, while multifocal GME will affect the brain or brain
and spinal cord, and focal GME will focus singly on either the
brain or spinal cord. Common symptoms associa