|Hepatitis C genotype info Nov 25, 2001 I have recently been
diagnosed with Hep C and would like to know how the genotype is
determined; and why is the prognosis different depending on the
genotype? | Response from Dr. Fried Hepatitis C genotyping is
performed on a blood sample, using similar methods that are used
for PCR tests of HCV levels. Genotypes are predictive of the
likelihood of sustained virological response for all interferon-
based treatments. Genotype 1, most common in the US, is less
responsive to therapy than genotypes 2 or 3. BUT REMEMBER,
genotype only gives an ESTIMATE of your chance of success, it
cannot predict any single individual's chance of sustained
response. Therefore, we don't use it alone to determine whether
or not a person should be treated. The exact reason why certain
genotypes respond less well than others is not known. Get Email
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