S. Faubel and J. Topf5 Osmoregulation If plasma osmolality is
high, water osmotically flows from the intracellu-lar
compartment into the plasma and interstitial compartments. This
move-ment of water causes cells to shrink, disrupting their
function.If plasma osmolality is low, water osmotically flows
from the plasma andinterstitial compartments into the
intracellular compartment. The cells swellfrom the influx of
water leading to decreased cellular function and, if se-vere,
cell lysis and death.Because of the potentially devastating
consequences of abnormalities inplasma osmolality, tight control
is important. Changes in plasma osmolality can change cell vol-
ume and disrupt cell function. Osmoregulation is important
because fluctuations in plasmaosmolality can cause changes in
cell _______.Decreased plasma osmolality causes water to flow
_______ cellswhich ________ (increases/decreases) cell volume
and disruptsfunction.aaavolumeintoincreases Consequence of low
plasma osmolalityConsequence of high plasma osmol