Definition of Children of the night Children of the night: Term
applied sometimes to children with xeroderma pigmentosum, a
genetic disease with such extraordinary sensitivity to sunlight
that ordinary sun exposure results in the development of skin
cancer at a very early age. Children with xeroderma pigmentosum
(XP) can only play outdoors safely after nightfall. Last
Editorial Review: 6/14/2012 Back to MedTerms online medical
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