Print friendly version Acute intermittent porphyria Other Names
for this Disease - HMBS deficiency - Hydroxymethylbilane
synthase deficiency - PBGD deficiency - Porphobilinogen
deaminase deficiency See Disclaimer regarding information on
this site. Some links on this page may take you to organizations
outside of the National Institutes of Health. Acute intermittent
porphyria (AIP) is one of the liver (hepatic) porphyrias. AIP is
caused by low levels of porphobilinogen deaminase (PGBD), an
enzyme also often called hydroxymethylbilane synthase. The low
levels of PGBD are generally not sufficient to cause symptoms;
however, activating factors such as hormones, drugs, and dietary
changes may trigger symptoms. Although most individuals with AIP
never develop symptoms, symptomatic individuals typically
present with abdominal pain. Treatment is dependent on the
symptoms. - Acute Intermittent Porphyria (AIP). American
Porphyria Foundation. http://www.porphyriafoundation.com/about-
porphyria/types-of-porphyria/AIP. Acc