Vaccine Safe and Tolerated Based on New Alzheimer’s Clinical
Trial Larger trials needed to confirm safety and establish
effectiveness of vaccine June 10, 2012 Source: Lancet Neurology
A study led by Karolinska Institutet in Sweden reports for the
first time the positive effects of an active vaccine against
Alzheimer's disease. The new vaccine could be an important step
forward in the search for a new treatments. The study is
published in the distinguished scientific journal Lancet
Neurology. Alzheimer's disease is a complex neurological
dementia disease that is the cause of much human suffering and a
great cost to society. The prevailing hypothesis about its cause
involves APP (amyloid precursor protein), a protein that resides
in the outer membrane of nerve cells and that, instead of being
broken down, form a harmful substance called beta-amyloid, which
accumulates as plaques and kills brain cells. There is currently
no cure for Alzheimer's disease, and the medicines in use can
only mitigate the symptoms. In