Fecal microbiota transplantation for the management of Clostridium difficile infection.
This article discusses the use of fecal microbiota transplantation (FMT) for the treatment of recurrent Clostridium difficile infection (CDI) The disruption of the normal gut microbiota is central to the pathogenesis of CDI, and disruption persists in recurrent disease. The use of FMT for recurrent CDI is characterized by a high response rate and short term safety is excellent, although the long term effects of FMT are as yet unknown.
Infectious disease clinics of North America