Ling Chang Lei Dong Wu De Ji Yin Ding Xiang Xiu Shi Ji Yun Yong CRISPR/Cas9Ji Zhu Huo De Ji Yin Ding Xiang Qiao Chu Shi Xie Hou
Zao Zai 2001Nian 1Yue ,Mei Guo Ke Xue Jia Zai ScienceShang Bao Dao Liao Shi Jie Shang Di Yi Zhi Zhuan Ji Yin Heng He Hou ,Ta Men Li Yong Man Bing Du Zhuan Ran Fa Cheng Gong Di Jiang Lu Se Ying Guang Dan Bai (GFP)Zhuan Ru Heng He Hou Zao Qi Pei Tai ,Bing Tong Guo Pei Tai Yi Zhi Huo De Liao GFPZheng He He Biao Da De Zhuan Ji Yin Hou ANDi,Zhe Shi Zhuan Ji Yin Ji Zhu Zai Fei Ren Ling Chang Lei Shang De Shou Ci Cheng Gong Chang Shi 2008Nian ,Shang.HsunYangDeng Ren Cheng Gong Gou Jian Chu Liao Heng Ting Dun Ji Bing (HD)De Zhuan Ji Yin Heng He Hou Mo Xing ,Zuo Zhe Jiang 84Ge CAGZhong Fu Xu Lie Lian Jie Dao Ren HTTJi Yin Di Yi Ge Wai Xian Zi Shang ,Bing Jiang Qi Bao Zhuang Cheng Gao Di Du De Man Bing Du Li Zi (Di Du 109PFU/mL)Hou ,Zai Luan Mu Xi Bao Dai Xia Zhu She Bing Du Hou Zai Jin Xing Dan Jing Zhu She Shou Jing He Pei Tai Yi Zhi ,Cheng Gong De Dao Liao Di Yi Ge Zhuan Ji Yin Fei Ren Ling Chang Lei Ji Bing Mo Xing Ran Er ,Tong Guo Man Bing Du Jie Dao De Fang Shi Chan Sheng De Zhuan Ji Yin Dong Wu ,Wai Yuan Ji Yin De Sui Ji Cha Ru Shi De Ta De Biao Da He Gong Neng De Shi Xian Ju You Yi Ding De Bu Que Ding Xing Zai Ling Chang Lei Dong Wu Zhong ,You Yu Ji Zhu Xian Zhi Wu Fa Tong Guo Yu Da Xiao Shu Tong Yang De Ji Zhu Lu Xian Huo De Jing Que Ji Yin Xiu Shi De Dong Wu Yi TANLENs, CRISPR/Cas9Ji Zhu Wei Dai Biao De Ren Gong He Suan Mei Jie Dao De Ji Yin Zu Bian Ji Ji Zhu De Dan Sheng ,Shi De Zai Ling Chang Lei Dong Wu Zhong Shi Xian Jing Que Ji Yin Xiu Shi Cheng Wei Ke Neng Ji Wei Zhi Yan Jiu Yuan Tuan Dui Yu Nan Jing Yi Ke Da Xue Sha Jia Hao Jiao Shou He Nan Jing Da Xue Huang Xing Xu Jiao Shou Tuan Dui Mi Qie He Zuo ,Cheng Gong Yun Yong Crispr/Cas9Ji Zhu Huo De Liao Shi Jie Shang Shou Li Ji Yin Ding Xiang Qiao Chu Shi Xie Hou ,Zheng Shi Liao CRISPR/Cas9Xi Tong Ke Yi Zai Ling Chang Lei Dong Wu Zhong Hen Hao Di Gong Zuo ,Bing Chan Sheng Huo Ti Dong Wu Zhe Wei Ling Chang Lei Ji Bing Dong Wu Mo Xing De Fa Zhan Dian Ding Liao Liang Hao De Ji Chu