Role of Adjunct Therapy of Antibiotics and Antioxidant Therapy in Dogs Suffering from Gastroenteritis
Gastroenteritis may influence oxidative indices and such conditions may be targeted with supportive antioxidant therapy. In recent years, emphasis has been given on the antioxidants as the potential drugs of interest for management of diseases (Chandrasena et al. 2014) Excessive production of free radicals and their metabolites, called reactive oxygen species (ROS) exhibit several harmful effects which lead to oxidative damage of various metabolic products. Reactive Oxygen species (ROS) can be scavenged by antioxidant system which includes antioxidant enzymes like glutathione peroxidase, catalase and superoxide dismutase and non enzymatic components involving vitamin E, vitamin C, vitamin A and selenium (Ighodaro and Akinloye, 2018) The antioxidant mechanism of vitamin C is based on the donation of hydrogen atom to lipid radicals, quenching of singlet oxygen and removal of molecular oxygen (Levine et al. 1999) NInternational Journal of Current Microbiology and Applied Sciences ISSN: 2319 7706 Volume 9 Number 2 (2020) Journal homepage: http:/www.ijcmas.com