A Comparative Study Between Transplantation of Conjunctival Limbal Autograft with Mitomycin C and Amniotic Membrane Transplantation with Mitomycin C in Recurrent Pterygium
Introduction: Pterygium, a wing shaped encroachment of the cornea by the conjunctiva, Conjunctival limbal autograft with stem cell (CLAU) or amniotic membrane transplantation (AMT) has been widely adopted in the management of pterygium. Purpose: To compare the efficacy and the complications of conjunctival limbal autograft (CLAU) with mitomycin C 0.2 and amniotic membrane transplantation (AMT) with mitomycin C 0.2 for treatment of recurrent pterygium Subject and methods: 80 eyes of 60 patients clinically diagnosed with recurrent pterygium were divided into two groups group A included 40 eyes underwent pterygium excision and MMC 0.2% with CLAU group B included 40 eyes underwent pterygium excision and MMC 0.2% with AMT Recurrence was defined as fibrovascular tissue extension of more than one mm onto the cornea in the area of previously excised pterygium. Mean follow up period 8+ 1 month. Recurrence was compared in each group by using 2 test. Results:No major postoperative complications occurred during 6 9 months of followup. In CLAU group (A) only 5 eyes of recurrence occur (12.5% after 7 months of follow up. Recurrence occur in 12 eyes (30% in AMT group (B) after 6 months (P value =0.043, 2 test).The operated site was look like the normal adjacent site in 77%of the non recurrence group A versus 10% in group B Conclusion: CLAU with MMC is more effective than AMT with MMC for treatment of recurrent pterygium and the final cosmetic appearance is more acceptable in CLAU group than AMT group B.