Administering atropine and ketamine before less invasive surfactant administration resulted in low pain scores in a prospective study of premature neonates
Less invasive surfactant administration (LISA) can avoid tracheal intubation for neonatal respiratory distress syndrome, but can be painful because it requires laryngoscopy. The aim of this study was to assess the efficacy and tolerance of intravenous atropine plus ketamine administration before LISA.
Acta paediatrica