On the treatment of peptic ulcer patho physiological considerations
layers of rumen and body. These cells were identified as mast cell by metachromasia of the cytoplasmic granules with toluidine blue. The gastric ulceration due to cold stress was produced mainly in the body, and its ulceration occured in the antrum and rumen after the prolonged exposure to the cold stress. The fluorescent mast cells in the serosal, muscular and submucosal layer of the gastric body of the cold stressed rat increased markedly in number and in intensity of the fluorescence. The newly appeared fluorescent mast cell were usually distributed along the blood vessel, paticularly in the muscular layer. The degree and number of the gastric ulceration due to cold and restraining stress were diminished with Pyridinol calbamate administration. And also the newly appearance of fluorescent mast cells due to the stresses were was inhibited with the administration of Pyridinolcalbamate.
Gastroenterologia Japonica