At the 2021 Winston-Salem Open Ivashka reached his fourth quarterfinal for 2021, defeating ninth seeded Jan-Lennard Struff, and his second semifinal defeating top seed and World No. 12 Pablo Carreno Busta.[7][8] He then defeated Emil Ruusuvuori to reach his first ATP final and then defeated Mikael Ymer for the title in 56 minutes to become the first player from Belarus to win an ATP Tour singles title since Max Mirnyi in 2003 at Rotterdam.[9] He became the eighth First-Time ATP Tour Champion in 2021.[10] As a result of the victory, he entered the top 60 at World No. 53 on 30 August 2021 for the first time in his career.