The university was founded on September 15, 1936, by a decree of the Catholic Archbishop of Medellín, Monsignor Tiberio de Jesús Salazar y Herrera as the Universidad Católica Bolivariana (UCB, Catholic Bolivarian University). The UCB started with a small faculty and 78 students enrolled in the School of Law and with Monsignor Manuel José Sierra as its first rector. In 1945, the university received the title of Pontifical, from the Holy See under Pope Pius XII.