During his career on the Hebrew stage, Meskin played many leading roles, including Othello; the Golem; Shylock (in The Merchant of Venice); Willy Loman in Death of a Salesman; the black pastor Stephen Kumalo in Cry, The Beloved Country; Captain Queeg in The Caine Mutiny and many others. His final performance was in Nisim Aloni's The Gypsies of Jaffa, produced in 1971.