2% of people under 65 years of age have chronic smelling problems. This increases greatly between people of ages 65 and 80 with about half experiencing significant problems smelling. Then for adults over 80, the numbers rise to almost 75%.[1] The basis for age-related changes in smell function include closure of the cribriform plate,[2] and cumulative damage to the olfactory receptors from repeated viral and other insults throughout life.