Since not all mycotoxins can be bound to such agents, the latest approach to mycotoxin control is mycotoxin deactivation. By means of enzymes (esterase, de-epoxidase), yeast (Trichosporon mycotoxinvorans), or bacterial strains (Eubacterium BBSH 797 developed by Biomin), mycotoxins can be reduced during pre-harvesting contamination. Other removal methods include physical separation, washing, milling, nixtamalization, heat-treatment, radiation, extraction with solvents, and the use of chemical or biological agents.