On January 24, 2013, Mehmet Müezzinoğlu was appointed as Minister of Health in the cabinet of Recep Tayyip Erdoğan, replacing Recep Akdağ.[1][4] He kept his post in three successive cabinets of Ahmet Davutoğlu. On 24 May 2016, the Third Davutoğlu Cabinet was dissolved, and Müezzinoğşu's term as Health Minister ended. On 31 August 2016, he was appointed Minister of Labour and Social Security in the Cabinet of Yıldırım replacing Süleyman Soylu.