Elisha Warfield Theobald (1818–1851), husband of Nathan Ryno Smith's Sr.'s daughter, Sarah Frances Smith Theobald, was a physician as well. Her younger son, Elisha Warfield Theobald Jr., (1850–1877) was a physician but did not live long enough to make a great impact on the profession. However Samuel Theobald, Sarah's older son, became head of the American Ophthalmological Society and was from 1893-1925 an active professor at Johns Hopkins University (he was emeritus for the next five years until his death).