She was mentored by and collaborated with Mary Jeanne Kreek. While at Rockefeller, she met Sheldon Adelson, whom she married in 1991. In 1993, she founded a substance abuse center and research clinic there, and in 2000, the couple opened the Dr. Miriam and Sheldon G. Adelson Research Clinic in Las Vegas.[1] A strong supporter of Israel, she admitted her heart has always been in that country and that she got "stuck" in America after meeting her husband.[10] She is credited with influencing Sheldon's political views on Israel[3] and served as one of the 'finance vice-chairs' for the inauguration of Donald Trump.[11]