Ferrous iron, iron (II), is soluble and its toxicity varies, largely with the integrity of the gastrointestinal lining. Iron supplements are typically used to treat anemia. Modalities include: diet, parasite control,[5] vitamin A, riboflavin (B2),[6] vitamin C (for absorption), folate(B9), vitamin B12 and multivitamin-multimineral supplements,[7] with or without iron; potentially avoiding the use of iron only supplements.[8]