G.M Syed started his political career at the age of 16, when he organised Khilafat Conference at his hometown, Sann, on 17 March 1920.[8] He was first to become a political prisoner after the creation of Pakistan in 1948.[9][2] He restated the political implementation of Sufi ideologies proposing peaceful religious coexistence, secularism, Sindhi nationalism and laid the basis for Sindhudesh Movement.[10] He spent approximately thirty years of his life in imprisonment and house arrests for opposing the anti-Sindh policies.[11] He was entitled as the prisoner of conscience by Amnesty International in 1995.[12] He died during his house arrest in Karachi on 26 April 1995.[13]