The method of instillation abortion was first developed in 1934 by Eugen Aburel.[4] It is most frequently used between the 16th and 24th week of pregnancy, but its rate of use has declined dramatically in recent years.[2] In 1968, abortion by the instillation of saline solution accounted for 28% of those procedures performed legally in San Francisco, California.[5] Intrauterine instillation (of all kinds) declined from 10.4% of all legal abortions in the U.S. in 1972 to 1.7% in 1985,[6] falling to 0.8% of the total incidence of induced abortion in the United States during 2002,[7] and 0.1% in 2007.[8]