Recently, a new approach to exploiting viruses and their capsids for biotechnology began to change toward using them for nanotechnology application. Researchers Douglas and Young (Montana State University, Bozeman, MT, USA) were the first to consider the utility of a virus capsid as a nanomaterial.[17] They have taken plant virus Cowpea Chlorotic Mottle Virus (CCMV) for their study. CCMV showed a highly dynamic platform with pH and metal ion dependent structural transitions.