Almost all registered microbes are biopesticides, producing some $1 billion annually, less than 1% of the chemical amendment market, estimated at $110 billion. Some microbes have been marketed for decades, such as Trichoderma fungi that suppress other, pathogenic fungi, and the caterpillar killer Bacillus thuringiensis. Serenade is a biopesticide containing a Bacillus subtilis strain that has antifungal and antibacterial properties and promotes plant growth. It can be applied in a liquid form on plants and to soil to fight a range of pathogens.