Similarly, FGF is being inserted into fibrin sealants to enhance the long term repair and sealing of tissue.[1] FGF-1 has been experimentally shown to encourage the body’s own adhesive tissue to develop and effectively seal the wound (thereby stymieing infection and mitigating scar formation).[6] Using FGF stimulate fibroblast activity is a more effective means of sealing tissue than current tissue sealants due to the robust nature of collagen which makes up connective tissue. A study conducted by researchers at the University of Alabama examined the adhesive properties of fibrin tissue adhesives. The tests found that fibrin adhesives even at its intended medical concentration (29 mg/mL at the wound site) had shear strength of only 17.6 kiloPascals.[2] Furthermore, another study performed at the University of California determined that the modulus (the stress/strain) of fibrin adhesives was on average 53.56 kPA.[3] To seal together tissues the human body uses collagen and elastin to obtain superior shear strength.