The combination was approved for medical use in the United States in 1984.[2] It is available as a generic medication.[4] In the United States the wholesale cost is about 1.20 USD per dose as of 2019.[10] In 2017, it was the 187th most commonly prescribed medication in the United States, with more than three million prescriptions.[11][12] In the United States it is a schedule III controlled substance[13] in some states but not federally.[3][14][15] It is banned in a number of European countries.[8]