"Opposites Attract" became one of the most popular R&B and dance-pop singles of 1990. The single initially rose from number 72 to number 47 the week of December 23, 1989, and landed at number one the week of February 10, 1990, where it remained for three weeks, matching the run of "Straight Up". It became Abdul's fourth number-one single on the Billboard Hot 100 and made her only the fourth artist in music history to score four number-one hits from a single album, after Whitney Houston, George Michael and Michael Jackson.