She used a multidisciplinary approach, applying biochemical, electrophysiological, pharmacological, anatomical and behavioral techniques to study working memory.[2] She pioneered the first studies of dopamine influences on prefrontal cortical function, research that is critical to our understanding of schizophrenia, ADHD and Parkinson's disease. A review of her life's work, including her special role mentoring women scientists, can be found in the journal Neuron.[11]