Rotavirus A, which accounts for more than 90% of rotavirus gastroenteritis in humans,[54] is endemic worldwide. Each year rotavirus causes millions of cases of diarrhoea in developing countries, almost 2 million resulting in hospitalisation[7] and an estimated 453,000 resulting in the death of a child younger than five.[9] This is about 40 per cent of all hospital admissions related to diarrhea in children under five worldwide.[55]