Significant advances in the medical sciences took place during the Punto Fijo pact period. Jacinto Convit developed vaccines against leprosy and leishmaniasis,[11] and Baruj Benacerraf was a co-recipient of the Nobel Prize in Physiology or Medicine in 1980 for his immunological research.[12] In the field of technology, Humberto Fernández Morán invented the diamond knife and contributed to the development of the electron microscope.