Allbritton's interest in single-cell analysis have hinged on the use of capillary electrophoresis (CE) and microfabricated technologies. Through this work she has studied lipid signaling at the single-cell level, the isolation cytotoxic t-cells with specific properties, and the capture of colonic crypts. In the organ-on-a-chip field, Allbritton has focused on developing devices that effectively capture the environment of both the small and large intestine.[citation needed]