This dichotomy is likely due to a wider range of sensitive targets in Eukaryota. For example, organophosphate esters that interfere with nerve signal transmission in insects do not affect microbial processes and offering nourishment for microorganisms whose enzymes can hydrolyze phosphotriesters. Bacteria are more likely to contain such enzymes because of their strong selection for new enzymes and metabolic pathways that supply essential nutrients.[2] In addition, genes move horizontally within microbial populations, spreading newly evolved degradation pathways.[2]