Thomas Palaiologos Despot of the Morea Thomas, detail from the Pintoricchio fresco of Pius II's arrival at Ancona, in the Siena Cathedral Reign 1428–1460 Predecessor Constantine Palaiologos Born 1409 Died 12 May 1465(1465-05-12) (aged 55) Spouse Catherine Zaccaria Issue Helena Andreas Manuel Sophia-Zoe Dynasty Palaiologos Father Manuel II Palaiologos Mother Helena Dragaš Signature