Vascular endothelial growth factor (VEGF) is known to be associated with sea fan lesions which are types of neovascularization.[1] Bevacizumab is an anti-VEGF drug used in intravitreal injection that is known to cause reversal of sea fan lesions and reduce the duration of vitreous hemorrhage.[2][4] Intravitreal injection of anti-VEGF drugs can also be used prior to surgery to aid separation of tissues involved in the sea fan lesion and to reduce intraoperative and postoperative hemorrhage.[3][4] It is useful in combination with photocoagulation.[3]