Totonji was born in Riyadh.[6] She earned her bachelor's and master's of fine arts degrees from George Mason University.[6] Totonji earned her Islamic Calligraphy Master's Certificate (Ijazah) in Jordan and earned her PhD in fine art in Ireland.[6] She studied Graphic Design at the Art Institute of Washington. Huda Ahmad Totonji has been teaching a graphic design at Dar Al-Hekma College, Jeddah, KSA. She often lectures in universities in Washington Metropolitan area and others the likes of Georgetown University, George Washington University, Howard University, Montgomery College, Oregon State University, Portland State University, Kansas State University, Penn State University, University of the Sciences in Philadelphia, Texas A&M University, and in Griffith University in Brisbane, Australia and others.[7]