Most versions of Burow's solution such as the American brand Domeboro can be used as a soak or compress. As an approved astringent by the FDA, Domeboro is used for the relief of skin irritations due to poison ivy, oak and sumac, rashes from allergic reactions to soaps, detergents, cosmetics and jewelry. This is due to the combination of two active ingredients found in this version of Burow's solution, i.e. aluminum sulfate tetradecahydrate and calcium acetate monohydrate.[7][8][9]