Memory relies on the strengthening of these neural pathways, associating one neuron with another. When we learn something, new pathways are made between neurons in the brain which then communicate through chemical signals. If these cells have a history of sending out certain signals under specific chemical conditions within the brain, they are then primed to work most effectively under similar circumstances.[6] State-dependent memory happens when a new neural connection is made while the brain is in a specific chemical state - for instance, a child with ADHD learns their multiplication tables while on stimulant medication.