Between August and October 1924, Wong's medical clinic, Po Chi Lam, was destroyed when the Nationalist government was suppressing the uprising by the Guangzhou Merchant Volunteers Corps. Wong felt so dejected and saddened by the loss of Po Chi Lam that he fell into depression and became ill. He died from illness on 17 April 1925 in Chengxi Fangbian Hospital (城西方便醫院),[6] which is the present day location of the Guangzhou First People's Hospital (廣州市第一人民醫院) at Panfu Road in Guangzhou's Yuexiu District.[7] He was buried at the foot of Baiyun Mountain.[3]