Khadeeja was the eldest daughter of Omar I of the Maldives. After the death of her father Sultan Omar in 1341, his son Ahmed Shihabuddine ascended the throne as Ahmed Shihabuddine of the Maldives. Khadija had her brother, the Sultan Ahmed Shihabuddine assassinated and took the throne for herself in 1347, becoming the first female ruler of Theemuge Dynasty.