Dominic Cooper as Jesse Custer: A small town preacher who is on a mission to find God.[3] Ruth Negga as Tulip O'Hare: The gun-toting ex of Custer.[4] Joe Gilgun as Cassidy: An Irish vampire and the best friend of Custer.[5] Lucy Griffiths[6] as Emily Woodrow: A character described as a "no-nonsense" single mother, waitress, church organist, bookkeeper and Custer's loyal right hand.[citation needed] W. Earl Brown as Sheriff Hugo Root: The mean-hearted father of Eugene Root, a flinty-eyed, conspiracy-credulous redneck who is not a fool and has a vulnerability to him.[clarification needed][7] Anatol Yusef as DeBlanc: one of two Adelphi angels tasked with watching the half-demon, half-angelic creature named 'Genesis'. Tom Brooke as Fiore: one of two Adelphi angels tasked with watching the half-demon, half-angelic creature named 'Genesis'.[8] Derek Wilson as Donny Schenck: "A Civil War re-enactor and abusive thug who gets into altercations with Jesse Custer but nevertheless shows up to church on Sunday."[9] Ian Colletti as Eugene Root / Arseface:[10] Sheriff Root's son, disfigured after shooting himself in the face with a shotgun and surviving.[citation needed]