1999: The first ICSI birth by frozen sperm of a gonadectomized man, Royan Institute 2003: The first human embryonic Stem Cell line establishment in Iran and the region, Royan Institute 2005: Establishment of the first Private Cord Blood Bank in Iran (Royan Stem Cell Technology Co.) 2006: Iran's first cloned sheep, named Royana, Royan Institute 2009: The first cloned goat born in Iran, Royan Institute 2010: The first transgenic goats born in Iran, Royan Institute 2011: Establishment of cell therapy pre-hospital, Royan Institute 2015: A new formulation of anti-breast cancer drug Herceptin using a bacterial method by researchers led by Keyvan Majdzadeh produced [2] 2017: The first transgenic zebrafish models in Iran, Royan Institute