In the early 14th century, the strife between Guelphs and Ghibellines, which plagued much of Italy, also affected Recanati. In a series of incidents, citizens of Recanati, among the others, ravaged and plundered the cathedral, and later killed some Guelph (pro-papal) exponents. In response, in 1322, papal mercenaries besieged Recanati, and destroyed its fortifications, the main Ghibelline palaces, and the Priors' Palaces.