As with any new technology, the earliest exposures are expected to occur among workers conducting research in laboratories and pilot plants. It is recommended that researchers handling engineered nanomaterials in these contexts perform that work in a manner that is protective of their safety and health.[1]:1 Control measures for nanoparticles, dusts, and other hazards are most effective when implemented within the context of a comprehensive occupational safety and health management system, the critical elements of which include management commitment and employee involvement, worksite analysis, hazard prevention and control, and sufficient training for employees, supervisors, and managers.[5]