He was later appointed chief muhtasib in Cairo by Sultan al-Mansur Qalawun in 1290, but was soon after exiled to the Hejaz. When al-Ashraf Khalil succeeded Qalawun in November 1290, he recalled Ibn al-Sal'us to Cairo and appointed him wazir. Ibn al-Sal'us restored the political influence of the office of wazir and accompanied al-Ashraf Khalil during military expeditions against the Crusaders and the Armenians.