Lewis's laboratory works on the directed assembly of soft functional materials. This work involves microfluidics, materials synthesis, complex fluids, and robotic assembly to design functional materials. She develops novel materials that can find potential application as printed electronics, waveguides, and 3D scaffolds and microvascular architectures for cell culture and tissue engineering.[1] As of early 2017, Lewis is the author of more than 160 papers and holds 11 patents, including patents for inventions as varied as methods to 3D print functional human tissue[6] and microbattery cells.[7]