The province of Medio Campidano (Italian: provincia del Medio Campidano; Sardinian: provìntzia de su Campidanu de Mesu) was a province in the autonomous region of Sardinia, Italy. As of 2015, the province had a population of 100,141 inhabitants over an area of 1,517.34 square kilometres (585.85 sq mi), giving it a population density of 66 inhabitants per square kilometre.