United States Strategic Command (USSTRATCOM) is one of the eleven unified combatant commands in the United States Department of Defense. Headquartered at Offutt Air Force Base, Nebraska, USSTRATCOM is responsible for strategic deterrence, global strike, and operating the Defense Department's Global Information Grid. It also provides a host of capabilities to support the other combatant commands, including integrated missile defense; and global command, control, communications, computers, intelligence, surveillance, and reconnaissance (C4ISR).