El-Sheikh became an academic staff member of the School of Management Studies at the Ahfad University for Women in 2002.[3] El-Sheikh is interested in promoting corporate social responsibility.[6] She is a co-founder of the Impact Hub Khartoum website, which aims to provide "a cooperative environment for entrepreneurs, intellectuals and innovators".[7] At Impact Hub Khartoum, el-Sheikh holds the title of Head of Community Programs and aims to support sustainable development.[6]