Fever[7] Headache[7] Muscle aches[7] Inoculation eschar, which is dead, often black, tissue around a bite site[7] (see photo above) Eschars may or may not be present. Amblyomma ticks actively attack cattle or humans and can bite more than once.[4] In African tick bite fever, unlike what is typically seen with other Rickettsial spotted fevers when only one eschar is identified, multiple eschars may be seen and are considered pathognomonic.[7] Swollen lymph nodes near the site of the bite[7] Maculopapular and/or vesicular rash[8]