It often has a genetic cause and is associated with mesomelic dwarfism and a mutation on the X chromosome. The deformity can attempt be treated surgically by addressing the deforming bone and ligamentous lesions called "Vickers Ligament". This is an abnormal ligament formed between the Lunate bone of the wrist and the radius and it’s found in 91% of cases of Madelung's Deformity.