Stickler syndrome is a rare autosomal dominant connective tissue disorder estimated to affect approximately 1/7500 newborns. Symptoms include retrognathia, maxillary hypoplasia, cleft palate, hearing impairment, musculoskeletal anomalies and cardiac defects. Treatment generally includes supportive care for musculoskeletal deformities, recognition and treatment of early hearing loss, and reconstructive surgery.[44]