In March 2020 it was announced that Ashley Zukerman has been cast to portray Robert Langdon.[12] In June 2020 it was announced that Valorie Curry and Eddie Izzard had been cast as Katherine and Peter Solomon.[13] A few days later additional cast members were announced, Sumalee Montano as Sato, Rick Gonzalez as Nunez and Beau Knapp as Mal'akh.[14] In June 2021, Raoul Bhaneja, Sammi Rotibi, and Keenan Jolliff were cast in recurring roles.[15]