African tick bite fever is usually mild, and most patients do not need more than at-home treatment with antibiotics for their illness.[6] However, because so few patients with this infection visit a doctor, the best antibiotic choice, dose and length of treatment are not well known.[8] Typically doctors treat this disease with antibiotics that have been used effectively for the treatment of other diseases caused by bacteria of similar species, such as Rocky Mountain Spotted Fever.[8] For mild cases, people are usually treated with one of the following: