Body area of application;[1] body regions with thin skin are significantly more permeable to topical glucocorticoid than areas with thick skin.[6] Condition of the skin; topical glucocorticoids are absorbed for a larger extent through areas of inflammation or in peeled areas when compared to normal skin Age of the patient; infants and young kids who have much thinner skin than that of adults absorb topical glucocorticoids more easily[10] Presence of urea, dimethylsulphoxide, or other agents (e.g. salicylic acid) in vehicle that will raise the absorption rate Placement of occlusive dressing on the body area, that will raise the absorption rate[11]