Disease Typical first phase Typical second phase European (or "Western") subtype of tick-borne encephalitis virus[3][4] Relatively mild flu-like illness Affecting some cases, generally presenting with high fever and neurologic disease (encephalitis), meningitis and/or meningoencephalitis) Leptospirosis[5] 4–9 days of abrupt onset of flu-like illness Fever, jaundice, abdominal pain and diarrhoea. Organ failure in severe cases. Anthracosis[6] After approximately 4 days, patients develop flu-like illness with fever, nonproductive cough, and myalgias lasting approximately 4 days Without timely treatment, a second fulminant phase follows, characterized by hypotension and dyspnea.