Medtronic plc is an Irish-domiciled medical device company that generates the majority of its sales and profits from the U.S. healthcare system but is headquartered in the Republic of Ireland for tax purposes.[1][2] Medtronic has an operational and executive headquarters in Fridley, Minnesota in the U.S.[3][4] In 2015, Medtronic acquired Irish–tax registered Covidien (a U.S. tax inversion to Ireland from 2007), in the largest U.S. corporate tax inversion in history,[5][6] which enabled Medtronic to move its legal registration from the U.S. to Ireland.[7] Medtronic operates in 140 countries and employs over 100,000 people.[8]