Green fruit, leaves, and root or rhizomes might have been used in Polynesian cultures as a general tonic, in addition to its traditional place in Polynesian culture as a famine food.[1] Although Morinda is considered to have biological properties in traditional medicine, there is no confirmed evidence of clinical efficacy for any intended use.[10] In 2018, a Hawaiian manufacturer of noni food and skincare products was issued an FDA warning letter for marketing unapproved drugs and making false health claims in violation of the US Food, Drug and Cosmetic Act.[11]