Shir worked with Gideon Sa'ar when he was Likud chairman during the party's time in opposition between 2006 and 2009, and when he became Minister of Education in 2009.[1] She was placed twenty-ninth on the Likud list for the April 2019 elections,[2] a slot reserved for representative of Tel Aviv District.[1] She was elected to the Knesset as Likud won 36 seats. She was re-elected in September 2019 and 2020. On July 16, 2020 she made headlines by criticizing Prime Minister Netanyahu's politically driven response to the Covid-19 pandemic.