Computational devices have been created in CMOS for both biophysical simulation and neuromorphic computing. More recent efforts show promise for creating nanodevices for very large scale principal components analyses and convolution.[24] If successful, these efforts could usher in a new era of neural computing that is a step beyond digital computing,[25] because it depends on learning rather than programming and because it is fundamentally analog rather than digital even though the first instantiations may in fact be with CMOS digital devices.