Neurotoxicity leading to chemotherapy-induced peripheral neuropathy, a progressive, enduring and often irreversible tingling numbness, intense pain and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs, often with deficits in proprioception.[11] Fatigue Nausea, vomiting, or diarrhea Neutropenia (low number of a type of white blood cells) Ototoxicity (hearing loss) Extravasation if oxaliplatin leaks from the infusion vein it may cause severe damage to the connective tissues. Hypokalemia (low blood potassium), which is more common in women than men[12] Persistent hiccups[13] Rhabdomyolysis[14]