The Mobile Stroke Unit concept was first published in 2003 and realized in clinical practice in 2008 by Fassbender et al. at Saarland University, Germany, adhering to current guidelines and legislations.[1][4][5] This strategy of "bringing the hospital to the patient" strongly reduced time between alarm and therapy, allowing diagnosis-based triage to the appropriate target hospital and other novel option such as diagnosis-based blood pressure adjustment.[4] It increased treatment rates and improved care of cerebral hemorrhage, when compared to conventional in-hospital care as shown by them and other groups at Berlin, Germany; Houston, Texas, USA; Cleveland, Ohio, USA; or Drøbak and Oslo, Norway.[5][6][7][8] In 2016, more than 20 sites are investigating this concept. Further studies on long-term outcomes, cost-effectiveness and best setting are underway.