Bt cotton was created through the addition of genes encoding toxin crystals in the Cry group of endotoxin.[1] When insects attack and eat the cotton plant the Cry toxins or crystal protein are dissolved due to the high pH level of the insect's stomach. The dissolved and activated Cry molecules bond to cadherin-like proteins on cells comprising the brush border molecules.[1] The epithelium of the brush border membranes separates the body cavity from the gut while allowing access for nutrients. The Cry toxin molecules attach themselves to specific locations on the cadherin-like proteins present on the epithelial cells of the midgut and ion channels are formed which allow the flow of potassium.[1] Regulation of potassium concentration is essential and, if left unchecked, causes death of cells.