She was elected to six more terms and served from July 17, 1951 to January 3, 1965. While serving in Congress, she served on the House Government Operations, Interior and Insular Affairs, and Veterans Affairs Committees, chairing the latter's Veterans' Hospitals Subcommittee.[1] After struggling to win support for her economic redevelopment plans for her home district in West Virginia during the Eisenhower Administration, Congresswoman Kee threw her support behind President John F. Kennedy's campaign in 1960 and, through the Accelerated Public Works Act, funneled millions of dollars through an Area Redevelopment Administration to the state.[2] Karsten did not sign the 1956 Southern Manifesto, and voted in favor of the Civil Rights Acts of 1957 and 1960,[3][4] but voted present on the Civil Rights Act of 1964.[5] She did not run for re-election in 1964, and was succeeded in Congress by her son, James Kee.