Age ≥ 65 Aspirin use in the last 7 days (patient experiences chest pain despite ASA use in past 7 days) At least 2 angina episodes within the last 24hrs ST changes of at least 0.5mm in contiguous leads Elevated serum cardiac biomarkers Known Coronary Artery Disease (CAD) (coronary stenosis ≥ 50%) At least 3 risk factors for CAD, such as: Hypertension -> 140/90 or on anti-hypertensives Current cigarette smoker Low HDL cholesterol (< 40 mg/dL) Diabetes mellitus Family history of premature CAD Male first-degree relative or father younger than 55 Female first-degree relative or mother younger than 65