Recent studies have also found a connection between the disruption of social rhythms and the triggering of manic episodes in bipolar disorder.[18] Differentiating between zeitgeber disturbances that lead to depression and those that lead to manic episodes has proven difficult. However, in both unipolar and bipolar depression, the concept of social zeitgebers as potential risk factors has influenced the development of interventions to address this risk. For bipolar disorder, Interpersonal and Social Rhythm Therapy (IPSRT) is meant to regulate and normalize an individual's social rhythms, including meal times, personal relationships, exercise, and social demands.