Prior to UT Austin, McInnis served as vice provost for academic affairs at the University of Virginia. Over her almost 20 years' experience at UVA, McInnis held various academic leadership and administrative appointments, including vice provost for academic affairs, associate dean for undergraduate education programs in the College of Arts and Sciences, director of American Studies, and as a professor of art history. She joined the faculty of UVA in 1998, earned tenure in 2005 and became a full professor in 2011.