Her reputation and connections in the Western-learning community won Ine the patronage of Date Munenari, whose favour extended to her daughter, now named Takako.[17] As her mixed German–Japanese blood could lead her to suffer discrimination, Munenari had her change her name to Kusumoto Itoku.[lower-alpha 10][4] He extended a modest official rice stipend to Ine, and she was expected to be ready to serve in the women's quarters at the castle; she was one of three doctors present when Munenari's wife Yoshiko gave birth in 1867.[18] Ine had a busy practice in Uwajima and made frequent travel between Nagasaki and Uwajima during the 1860s. Munenari made effort on behalf of her father and Shūzō, who were arrested in 1861 in Edo by anti-foreign factions.[17] Shūzō was released in 1865 and returned to Uwajima, where in 1866 he married Takako.[18]