Changing her research to focus on YAG lasers, she recognized the potential of ultra-rapid pulsing, after watching a scientific program on television in 1975, in which a single mitochondrion was destroyed without bursting the cell surrounding it.[8] Working with Jean-Claude Griesemann, Aron-Rosa developed and patented the picosecond, ophthalmic Nd:YAG laser for eye surgeries in 1978.[4][8] Using this type of laser, she was able to perform posterior capsulotomies.[6]