Struthers has been a spokesperson for Christian Children's Fund (later renamed ChildFund), advocating on behalf of impoverished children in developing countries, mainly in Africa, and has been the spokesperson for International Correspondence Schools in television ads, pitching the famous line "Do you want to make more money? Sure, we all do!". Her activism has been satirized in Episode 19 of the seventh season of Grey's Anatomy, 3 Episodes of In Living Color Season 3 Episodes 6 & 18 and Season 4 Episode 27,[10] the South Park episodes "Starvin' Marvin" and "Starvin' Marvin in Space",[5] and the Denis Leary song Voices in my Head.[11]