As one of the most heavily used roads in Frankfurt, factories soon sprang up along its length as Germany industrialised in the 19th century, including the headquarters of Adler and Tenovis. A tramway, the modern day lines 11 and 21, soon followed, supported by the industries along its length. By the outbreak of World War I, there were around 40 factories along the length of the road, with more along the many side roads that branch off it.