Table 7: Drugs Highly Bound to Proteins NSAIDs Antibiotics Anti-H2 Statins Antipsychotics Diclofenac Cephazoline Omeprazole Clofibrate Chlorpromazine Ibuprofen Cefoperazone Antifungals Lovastatin Haloperidol Indomethacine Ceftriaxone Amphotericine B Simvastatine Chemotherapy Drugs Ketoprofen Cloxacilin Itraconazole Fluvastatine Chlorambucil Naproxen Oxacilin Ketoconazole Hypotensors Etoposide Phenylbutazone Clindamycin Barbiturates Hydralacine Melphalan Piroxicam Erythromycin Thiopental Irbesartan D-penicillamine Anaesthetics Teicoplanin Benzodiazepines Losartan Tamoxifen Bupivacaine Rifampicin Clonazepam Misoprostol Opioids Calcium Anthagonists Rifabutin Diazepam Prazosin Fentanyl Nimodipine Antidepresants Flunitrazepam Valsartan Methadone Nifedipine Amitriptyline Flurazepam ACE's Antipsychotics Nitrendipine Desipramine Lorazepam Fosinopropil Clozapine Antiarrhythmics Imipramine Midazolam Quinapril Fluoxetine Amiodarone Nortriptyline Nitrazepam Immunosuppressors Risperidone Quinidine Anticoagulants Oxacepam Ciclosporin Sertraline Propafenone Warfarin Temazepam Tacrolimus Zolpidem Lidocaine Antiemetics Beta Blockers Methylprednisolone Others Digoxin Ondansetron Carvedilol Prednisone Celecoxib Verapamil Antiepilectics Propanolol Budesonide Diphenhydramine Oral Antidiabetics Carbamazepine Diuretics - Ethinylestradiol Glibenclamide Valproic acid Furosemide - Mefloquine - - Spironolactone - Paclitaxel - - Torsemide - -