Permixon was used in a 2016 study.[7] Limited in vitro and animal model studies have investigated potential for use in the treatment of cancer.[8][9] However, according to the American Cancer Society, "available scientific studies do not support claims that saw palmetto can prevent or treat prostate cancer in humans".[10] Patients interested in taking saw palmetto extract for management of BPH are advised to consult first with a healthcare provider.[11]