Numerous animal models of uncontrolled hemorrhagic shock have demonstrated improved outcomes when a lower than normal blood pressure (mean arterial pressure of 60 to 70 mmHg) is taken as the target for fluid administration during active hemorrhage.[9] The first published study in humans, in victims of penetrating torso trauma, has demonstrated a significant reduction in mortality when fluid resuscitation was restricted in the prehospital period.[10] However, it is important to note that the objective of that study was the comparison between standard prehospital and trauma center fluid resuscitation versus delayed onset of fluid resuscitation (fluid not administered until patients reached the operating room).