In a report on 474 patients with renal amyloidosis, hereditary fibrinogen Aα chain disease represented only 1.3% of all cases whereas aberrant immunoglobulin-induced renal amyloidosis (e.g. AL amyloidosis) represented 86% of the cases).[1] Hereditary fibrinogen Aα-Chain amyloidosis is, however, the most common form of familial renal amyloidosis.[2][3]