It is semiaquatic and is often found in streams, near springs, in canals and drainage ditches, and under water troughs.[1] The Colorado River toad is known to breed in artificial water bodies (e.g., flood control impoundments, reservoirs) and as a result, the distributions and breeding habitats of these species may have been recently altered in south central Arizona.[5] It often makes its home in rodent burrows and is nocturnal.