On 5 July 2014, after his debut season, Talisca moved to Portuguese champions Benfica for a €4.75 million fee (agent fee included), the highest paid for a Bahia player.[3][4][5] On 18 July 2014, he scored his first goal for Benfica on his debut in their Taça de Honra semi-final win against Estoril.[6] On 12 September, he scored a hat-trick in an away victory against Vitória de Setúbal.[7] On 27 September, he scored two goals in a row against Estoril in an away win (3–2) and became the Primeira Liga's top goalscorer with five goals.[8] On 5 October, he scored his sixth goal in Portuguese league and maintained the top scorer lead.[9] On 31 October, he scored his eighth and fourth consecutive goal in Primeira Liga, in a home win against Rio Ave (1–0), keeping the top scorer lead.