Rh(D) status of an individual is normally described with a positive or negative suffix after the ABO type. e.g. Someone who is A Positive has the A antigen and the Rh(D) antigen, whereas someone who is A Negative lacks the Rh(D) antigen. The terms Rh factor, Rh positive and Rh negative refer to the Rh(D) antigen only. Antibodies to Rh antigens can be involved in hemolytic transfusion reactions and antibodies to the Rh(D) and Rh(c) antigens confer significant risk of Hemolytic disease of the fetus and newborn.