One of the main reasons for the rise in selection of antibiotic resistance (ABR) and MDR which led to the emergence of the ESKAPE bacteria is from the rash overuse of antibiotics not only in healthcare, but also in the animal, and agricultural sector.[8] Other key factors are due to misuse and inadequate adherence to treatment guidelines in antibiotic consumption and usage.[9] Due to these factors, fewer and fewer antibiotic treatments are becoming effective in eradicating ABR and MDR bacterial infections, while at the same time there are now no more new antibiotics being created due to lack of funding.[9] These ESKAPE pathogens, along with other antibiotic resistant bacteria, are a interweaved global health threat and are being addressed from a more holistic and One Health perspective.[3][8]