The antipyretic ibuprofen is effective in reducing fevers in children.[62] It is more effective than acetaminophen (paracetamol) in children.[62] Ibuprofen and acetaminophen may be safely used together in children with fevers.[63][64] The efficacy of acetaminophen by itself in children with fevers has been questioned.[65] Ibuprofen is also superior to aspirin in children with fevers.[66] Additionally, aspirin is not recommended in children and young adults (those under the age of 16 or 19 depending on the country) due to the risk of Reye's syndrome.[67]