Mirtazapine[67] Ki (nM) Species Ref SERT >10,000 Human [68][69] NET ≥4,600 Human [70][68] DAT >10,000 Human [68][69] 5-HT1A 3,330–5,010 Human [5][69] 5-HT1B 3,534–12,600 Human [8][69] 5-HT1D 794–5,010 Human [8][69] 5-HT1E 728 Human [69] 5-HT1F 583 Human [69] 5-HT2A 6.3–69 Human [8][69] 5-HT2B 200 Human [8] 5-HT2C 8.9–39 Human [8][69] 5-HT3 8.1 Human [71] 5-HT4L >10,000 Human [69] 5-HT5A 670 Human [69] 5-HT6 ND ND ND[69] 5-HT7 265 Human [69] α1A 1,815 Human [69] α2A 20 Human [69] α2B 88 Human [69] α2C 18 Human [69] β >10,000 Human [69] D1 4,167 Rat D2 >5,454 Human [69] D3 5,723 Human [69] D4 2,518 Human [69] H1 0.14–1.6 Human [72][8][69] H2 >10,000 Rat [73][72] H3 83,200 Human [72] H4 >100,000 Human [72] mACh 670 Human [8][70] VGSC 6,905 Rat [69] VDCC >10,000 Rat [69] Values are Ki (nM). The smaller the value, the more strongly the drug binds to the site.