M. haemofelis belongs to the phylogenetically diverse class Mollicutes, which comprises 8 genera: Ureaplasma, Spiroplasma, Asteroleplasma, Mesoplasma, Entomoplasma, Acholeplasma, Anaeroplasma, and Mycoplasma. Haemoplasmas is the name given to the trivial cluster that includes M. haemofelis and its close relatives.[1]