She was the first female university professor in Latin America and one of the first women allowed to teach medicine. She was a pioneering researcher in women's health, studying the use of radiation therapy rather than surgery for uterine tumors and developing a vaginoscope which revolutionized women's health care in Brazil. She established the first maternity ward and gynecological services at the Hospital Militar Central of Buenos Aires in 1925, which provided the first incubation services in the country.