He is most famous for starring as a main cast member on Keeping Up with the Kardashians and its spinoffs.[3][6] Disick's popularity on Keeping Up with the Kardashians led to the development of a house flipping show, Flip It Like Disick, that aired on E! Network.[7] In addition to starring on reality shows, Disick has pursued multiple business ventures, including starting a clothing brand, Talentless, investing in nightclubs, and running multiple vitamin companies.[8][7][10]