The advantages provided by chloroplast DNA manipulation has seen growing interest into this field of research and development, particularly in agricultural and pharmaceutical applications.[1] However, there are some limitations in chloroplast DNA manipulation, such as the inability to manipulate cereal crop DNA material and poor expression of foreign DNA in non- green plastids as mentioned before.[5] In addition, the lack of post- translational modification capability like glycosylation in plastids may make some human- related protein expression difficult.[6] Nevertheless, much progress has been made into plant transplastomics, for example, the production of edible vaccines for Tetanus by using a transplastomic tobacco plant.[7]