The rediscovery of Vitruvius's work had a profound influence on architects of the Renaissance, prompting the rebirth of Classical architecture in subsequent centuries. Renaissance architects, such as Niccoli, Brunelleschi and Leon Battista Alberti, found in De architectura their rationale for raising their branch of knowledge to a scientific discipline as well as emphasising the skills of the artisan. One of Leonardo da Vinci's best known drawings, the Vitruvian Man, is based on the principles of body proportions developed by Vitruvius in the first chapter of Book III, On Symmetry: In Temples And In The Human Body.