Contamination of medicinal plants with mycotoxins can contribute to adverse human health problems and therefore represents a special hazard.[34][35] Numerous natural occurrences of mycotoxins in medicinal plants and herbal medicines have been reported from various countries including Spain, China, Germany, India, Turkey and from the Middle East.[34] In a 2015 analysis of plant-based dietary supplements, the highest mycotoxin concentrations were found in milk thistle-based supplements, at up to 37 mg/kg.[36]