Were developed and implemented methods of production of such drugs as atophan, benzocaine, procaine, bromural, thiokol, ichtyol, validol, antipyrine, caffeine, alkaloids and others. In 1938, in MITHT under the leadership of academic A. N. Nesmeyanov (later President of the RAS) began work in the field of organometallic compounds. Also, the Institute prepared professionals for the companies producing such important national defense materials, such as tungsten, molybdenum, vanadium, and rare-earth elements.