On September 21, 2019, Appalachian State beat the University of North Carolina at Chapel Hill 34–31, representing the Mountaineer's first Power Five conference win since the victory at Michigan in 2007. On November 9, 2019, Appalachian State followed up their victory over the University of North Carolina at Chapel Hill with a victory over the University of South Carolina, beating the Gamecocks 20–15. 2019 was the first season the Mountaineers finished ranked in the final polls since joining the FBS, after briefly entering the top 25 during the 2018 season.