It was in this Palace that in 1591 a commission of eight cardinals met to revise the Bible for a printed edition, among them cardinal Marcantonio Colonna and Saint Robert Bellarmine. The building is characterized by frescoes painted by mannerist artists of the 16th century, attributed to Dutch painters, to Antonio Tempesta, and to the Zuccaris (Taddeo Zuccari and Federico Zuccari). Here in 1606 Caravaggio created masterpieces for the Colonna family, in exchange for refuge on his journey to Naples, between Zagarolo and Paliano he executed the Supper at Emmaus, Mary Magdalen in Ecstasy and perhaps Saint Francis in Prayer.