Biological: The resected tissue is submitted to histopathologic examination, because sub-clinical breast cancer foci occur in 0.1–0.9 per cent of the tissue specimens. Technical: The original Lejour technique incision plan had no horizontal limbs, and so did not produce horizontal scars; however, contemporary variants, such as the Modified Lejour Technique, employ small, horizontal incisions along the inframammary fold, in order to avoid redundant skin folds, especially in the reduction of very oversized breasts.[26]