After being an unused substitute in a 0–0 away draw against Club Atlético Huracán on 18 October 2009, Pezzella made his senior debut on 7 December 2011, starting in a 1–0 home win against Defensores de Belgrano for the season's Copa Argentina.[2] His league debut came on 2 March of the following year, where he played the full 90 minutes in a 0–0 home draw against Quilmes Atlético Club.[3]