Plasma contains a large variety of proteins including albumin, immunoglobulins, and clotting proteins such as fibrinogen.[1] Albumin constitutes about 60% of the total protein in plasma and is present at concentrations between 35 and 55 mg/mL.[2] It is the main contributor to osmotic pressure of the blood and it functions as a carrier molecule for molecules with low water solubility such as lipid-soluble hormones, enzymes, fatty acids, metal ions, and pharmaceutical compounds.[3] Albumin is structurally stable due to its seventeen disulfide bonds and unique in that it has the highest water solubility and the lowest isoelectric point (pI) of the plasma proteins.