Jean Michel Pouvesle has been working at the University of Orléans in France, in the Group for Research and Studies on Mediators of Inflammation (GREMI), experimenting with the effects of microplasma on cancer cells. Pouvesle along with other scientists has created a dielectric barrier discharge and plasma gun for cancer treatment, in which microplasma will be applied to both in vitro and in vivo experiments. This application will reveal the role of ROS (Reactive Oxygen Species), DNA damage, cell cycle modification, and apoptosis induction.