The amphiphilic nature of the moenomycins induce hemolytic activity, provide a long half-life in the blood stream, and creates a tendency to aggregate in aqueous solution. Comparison of moenomycins with an abridged isoprene chain of 10-carbons, show that the oligosaccharide can still tightly bind the enzyme active site, but in vivo the MIC significantly increases since the drug is unable to anchor itself to the cytoplasmic membrane and present its sugar moiety. Further studies are needed to determine the optimal length for favorable pharmacokinetic properties.[18]