Like any medical imaging utilizing ionizing radiation, there will be a minute degree of direct ionizing damage and indirect damage from free radicals created during the ionization of water molecules within cells. A rough estimate of the risk of fatal cancer from a panoramic radiograph is about 1 in 20,000,000.[4] The age of the person being imaged also alters the risk, with younger people having a slightly higher risk. E.g. the 1 in 10,000,000 risk would be doubled for someone in the 1-10 age group.[4]