The first official report of COACH syndrome was published in 1974 at the Montreal Children's Hospital, identifying two siblings, a brother and sister, presenting with all 5 components of the disorder. The report summarizes the family history and provides detailed case reports on the two siblings, analyzing all health abnormalities to reach a conclusion about the condition. The siblings both presented with the symptoms of congenital hepatic fibrosis, choroidal colobomata, dysmorphic features, polycystic kidneys, encephalopathy causing mental retardation and growth problems.