D'Amelio's career began on TikTok in the summer of 2019 with uploaded dance videos. She has since acquired over 43.6 million TikTok followers,[5] 11.9 million Instagram followers,[6] 2.58 million YouTube subscribers,[7] and over 846 thousand Twitter followers.[8] In just 10 months, she became the most-followed account on the social media platform TikTok. She surpassed the previous most-followed individual, Loren Gray, on March 25, 2020.[9]