In 245 BC, Andragoras, the Seleucid governor (satrap) of Parthia ("roughly western Khurasan"[1]) proclaimed independence from the Seleucids, when - following the death of Antiochus II - Ptolemy III seized control of the Seleucid capital at Antioch, and "so left the future of the Seleucid dynasty for a moment in question."[2]