After Tamerlane invaded Aleppo in 1400 and destroyed it, the Christians migrated out of the city walls and established their own neighbourhood in 1420, at the northwestern suburbs of the city, thus founding the quarters of al-Jdayde. The vast majority of the Christian population returned to Aleppo by the end of the 15th century. The Syrian Catholic population of the city had re-established its presence in Aleppo and re-built the church in 1500 and called it the Cathedral of Our Lady of the Syrians.