In bioinformatics, GLIMMER (Gene Locator and Interpolated Markov ModelER) is used to find genes in prokaryotic DNA.[1] "It is effective at finding genes in bacteria, archea, viruses, typically finding 98-99% of all relatively long protein coding genes".[1] GLIMMER was the first system that used the interpolated Markov model[2] to identify coding regions. The GLIMMER software is open source and is maintained by Steven Salzberg, Art Delcher, and their colleagues at the Center for Computational Biology[3] at Johns Hopkins University. The original GLIMMER algorithms and software were designed by Art Delcher, Simon Kasif and Steven Salzberg and applied to bacterial genome annotation in collaboration with Owen White.