This accumulation of iron is referred to as NBIA, or neurodegeneration with brain iron accumulation, and it is a symptom unique to a complex group of inherited neurodegenerative diseases such as KRS, characterized by this accumulation of iron in the basal ganglia.[13] Additionally, genetic screening through sequence analysis can allow definitive diagnoses of the disease by identifying mutations in the ATP13A2 gene, a gene closely associated with Kufor-Rakeb Syndrome.[2]