Enzyme kinetics: Why do some enzymes exhibit faster-than-diffusion kinetics?[8] Protein folding problem: Is it possible to predict the secondary, tertiary and quaternary structure of a polypeptide sequence based solely on the sequence and environmental information? Inverse protein-folding problem: Is it possible to design a polypeptide sequence which will adopt a given structure under certain environmental conditions?[5][9] This has been achieved for several small globular proteins in recent years.[10] RNA folding problem: Is it possible to accurately predict the secondary, tertiary and quaternary structure of a polyribonucleic acid sequence based on its sequence and environment? What are the chemical origins of life?