In a 1989 report, the Natural Resources Defense Council (NRDC) reported that on the basis of a two-year peer reviewed study, children were at "intolerable risk" from a wide variety of potentially lethal chemicals, including daminozide, that they ingest in legally permissible quantity. By their estimate, "The average pre-schooler's exposure was estimated to result in a cancer risk 240 times greater than the cancer risk considered acceptable by E.P.A. following a full lifetime of exposure."[5]