Matlin is actively involved with a number of charitable organizations, including Easter Seals (where she was appointed an Honorary board member), the Children Affected by AIDS Foundation, Elizabeth Glaser Pediatric AIDS Foundation, VSA arts, and the Red Cross Celebrity Cabinet.[35] She was appointed by President Clinton in 1994 to the Corporation for National Service and served as chair of National Volunteer Week.[36] Matlin was a participant in the first-ever national television advertising campaign supporting donations to Jewish federations.