Born in Ferrara, Mazzacurati was the daughter of the sculptor and painter Renato Marino Mazzacurati. Eager to embark on an acting career, at young age she moved to Rome, where she enrolled the Centro Sperimentale di Cinematografia, graduating in 1953.[1] She had made her film debut one year earlier, in the Leonardo Cortese's drama Art. 519 codice penale.[1]