However, homeopathic remedies that are less diluted than D4, or for which a danger of adverse effects exists, cannot be registered under this rule.[16] They can be sold over-the-counter in pharmacies. Germany is the only member state of the EU in which homeopathic remedies based on minerals or plants, and produced only in very low quantities, do not need to be registered. In other member states only remedies individually prepared in a pharmacy are exempt.[17]