The development of new technologies is increasing our ability to analyze the genome, and transcriptome, of single cells, as well as to quantify their proteome and metabolome.[7][8][9] New developments in mass spectrometry techniques have become important analytical tools for proteomic and metabolomic analysis of single cells.[10][11] In situ sequencing and fluorescence in situ hybridization (FISH) do not require that cells be isolated and are increasingly being used for analysis of tissues.[12]