U-605 was sunk on 14 November 1942 in the Mediterranean Sea in position 36°20′N 01°01′W﻿ / ﻿36.333°N 1.017°W﻿ / 36.333; -1.017Coordinates: 36°20′N 01°01′W﻿ / ﻿36.333°N 1.017°W﻿ / 36.333; -1.017, by depth charges from a RAF Hudson bomber. All hands were lost.