The thyroid, parathyroid, pituitary, or adrenal glands, and the pancreas are parts of the endocrine system, and, therefore are associated with the endocrine bone disease.[2] Some common endocrine disorders are hypothyroidism, hyperthyroidism, Paget's disease,[2] Osteoporosis, and diabetes.[3] The thyroid gland produces thyroxin (T3, and T4) which is necessary for normal development of the nervous system. Its functions include: promoting growth, increasing basal metabolic rate and controlling body temperature.[3] Adequate iodine intake is necessary for the production of thyroid hormone. According to Payton R. G. et al., a common disorder of the thyroid gland is hypothyroidism, which is more prevalent in women than in men.