Further work by the team established the mechanism by which hinokitiol restores or reduces cell iron.[41] They then switched their study to mammals and found that when rodents that had been engineered to lack “iron proteins” were fed hinokitiol, they regained iron uptake in the gut. In a similar study on zebrafish, the molecule restored Hemoglobin production.[42] A commentary on the work of Burke et al. nicknamed hinokitiol the “Iron Man molecule”. This is fitting/ironic because discoverer Nozoe’s first name can be translated into English as “iron man”.