Brugada syndrome is named after the Spanish cardiologists Pedro and Josep Brugada who described the condition in 1992,[1] although the association between the characteristic ECG pattern and sudden cardiac death had been reported in 1989.[38] Brugada syndrome was described as a cause for the sudden unexplained cardiac death syndrome seen in Thai men in 1997.[36] The first genetic mutations affecting the SCN5A gene associated with the syndrome were identified by their brother Ramon Brugada in 1998,[39] with many more mutations affecting at least 19 genes subsequently identified by others.[13] Studies in the 2000s led to competing theories surrounding the mechanisms by which abnormal heart rhythms were generated.[6] Research into Brugada syndrome is ongoing, identifying new genetic variants, exploring mechanisms of arrhythmias, and searching for better treatments.[11]