The anonymous Master of Signa was from the town. Other natives include the artists Bruno Catarzi, Giuseppe Santelli, Raffaello Fossi, Alimondo Ciampi, and Alvaro Cartei; the academics Tommaso Bisagno and Boncompagno da Signa; Blessed Giovanna da Signa; the journalist Piergiorgio Branzi; and the actor Giancarlo Gori.