At the 2020 US Open, Davidovich Fokina reached the fourth round of a Grand Slam for the first time in his career, beating Dennis Novak, Hubert Hurkacz, and Cameron Norrie, before losing in straight sets to Alexander Zverev. In Cologne 1, he reached the semifinals, beating qualifier Emil Ruusuvuori, 8th seed Marin Cilic, and Dennis Novak before losing to eventual champion and top seed Alexander Zverev in straight sets.