Pope Shenouda III called his secretary to be ordained as a General Bishop, ordaining him on 25 May 1980; Bishop Missael was sent to the United Kingdom, becoming the first bishop from the Coptic Orthodox Patriarchate to reside there. During his time as General Bishop, Bishop Missael consecrated St. Mary & St. Antony's Coptic Orthodox Church in 1985 and established St. Mary & St. Mark's Coptic Orthodox Centre in 1989 - both in Birmingham.