Chronic pancreatitis may develop as a result of acute pancreatitis. It is most commonly due to many years of heavy alcohol use. Other causes include high levels of blood fats, high blood calcium, some medications, and certain genetic disorders such as cystic fibrosis among others.[1] Smoking increases the risk of both acute and chronic pancreatitis.[2][3] Diagnosis of acute pancreatitis is based on a threefold increase in the blood of either amylase or lipase.