These alterations may consequently lead to serious reproductive problems following repeated exposure.[26][27] When exposed in utero or during lactation, a decrease in sperm motility and sperm count along with an increase in percent abnormal sperm was observed in rats at 0.4 mg/kg dose level.[28] In one study, the exposure of rats to sublethal amounts of carbofuran decreased testosterone by 88%, while the levels of progesterone, cortisol, and estradiol were significantly increased (1279%, 202%, and 150%, respectively).[27]