Since Serbs were, and still are, predominantly Eastern Orthodox Christians, their first significant historical encounter with Islam occurred in the second half of 14th century, and was marked by Turkish invasion and conquest of Serbian lands (starting in 1371 and ending by the beginning of 16th century). That interval was marked by first wave of Islamization among Serbs: in some regions, substantial minority left Christianity and converted into Islam, willingly or by necessity, under the influence of Ottoman authorities. The most notable Muslim of Serb ethnicity was Mehmed-paša Sokolović (1506-1579), Grand Vizier of the Ottoman Empire (1565-1579), who was ethnic Serb by birth, and so was Omar Pasha Latas.