Childhood ALL, testicular cancer, and Hodgkins disease, previously universally fatal, are now generally curable diseases. Conventional cytotoxic chemotherapy has shown the ability to cure some cancers, including testicular cancer, Hodgkin disease, non-Hodgkin lymphoma, and some leukemias. It has also proved effective in the adjuvant setting, in reducing the risk of recurrence after surgery for high-risk breast cancer, colon cancer, and lung cancer, among others.[when?]