One such infection is Osteomyelitis which can offer a unique challenges in treatment efforts, one novel approach has been the creation of antibiotic cement nails which can be inserted into the infected bone. First described by Paley and Herzenberg [16] antibiotic cement nails have dual purpose, both of stabilization of the bone being treated, and prevention against post-procedure infection. Antibiotic cement nails are inserted during surgery, and are produced around the time of procedure using materials available in the operating room setting.