Although there are various methods of taking drugs, injection is favoured by some users as the full effects of the drug are experienced very quickly, typically in five to ten seconds. It also bypasses first-pass metabolism in the liver, resulting in higher bioavailability and efficiency for many drugs (such as morphine or diacetylmorphine/heroin; roughly two-thirds of which is destroyed in the liver when consumed orally) than oral ingestion would, meaning users get a stronger (yet shorter-acting) effect from the same amount of the drug. This shorter, more intense "high" can lead to a dependency—both physical and psychological—developing more quickly than with other methods of taking drugs.