The Heartland virus (HRTV) is a tick-borne phlebovirus of the Bhanja virus serocomplex discovered in northwestern Missouri by Dr. Scott Folk of Heartland Regional Medical Center in St. Joseph, Missouri.[1] The virus was first proven to infect humans in June 2009[2] when two farmers, living 60 miles (97 km) apart, presented with fever, fatigue, diarrhea, thrombocytopenia, and leukopenia. The Lone Star Tick transmits the virus to people when feeding on blood.