A CPP is issued for a single product, because manufacturing arrangements and approved information for different pharmaceutical forms and strengths can vary.[2] The CPP is mentioned in World Trade Organization documents, although the tightly regulated products are subject to bilateral trade agreements or regional trade agreements.[3] The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) has instituted standards for this purpose but it is unclear how the ex-ICH countries operate their health regulators.[4][5]