Typically, people are treated with counseling and antidepressant medication.[1] Medication appears to be effective, but the effect may only be significant in the most severely depressed.[13][14] It is unclear whether medications affect the risk of suicide.[15] Types of counseling used include cognitive behavioral therapy (CBT) and interpersonal therapy.[1][16] If other measures are not effective, electroconvulsive therapy (ECT) may be considered.[1] Hospitalization may be necessary in cases with a risk of harm to self and may occasionally occur against a person's wishes.[17]