The name "coronavirus" is derived from Latin corona, meaning "crown" or "wreath", itself a borrowing from Greek κορώνη korṓnē, "garland, wreath".[11][12] The name was coined by June Almeida and David Tyrrell who first observed and studied human coronaviruses.[13] The word was first used in print in 1968 by an informal group of virologists in the journal Nature to designate the new family of viruses.[4] The name refers to the characteristic appearance of virions (the infective form of the virus) by electron microscopy, which have a fringe of large, bulbous surface projections creating an image reminiscent of the solar corona or halo.[10][13] This morphology is created by the viral spike peplomers, which are proteins on the surface of the virus.[14]