between Europe and Asia (dividing Eurasia): along the Turkish Straits, the Caucasus and the Urals (historically also north of the Caucasus, along the Kuma–Manych Depression or along the Don River) between Asia and Africa (dividing Afro-Eurasia into Africa and Eurasia): at the Isthmus of Suez between North America and South America (dividing the Americas): at some point on the Isthmus of Panama, with the most common demarcation in atlases and other sources following the Darién Mountains watershed that divides along the Colombia–Panama border where the isthmus meets the South American continent (see Darién Gap)