The most common way to contract the disease was through sexual intercourse with an infected woman. However, he did also believe that the disease could be spread through non-sexual contact and in rare cases spontaneously within the body.[1] The symptoms he describes were hard ulcers on the genitalia of the infected and in some cases including fever, pain in one’s extremities, swelling of the groin, hair loss, and varying manifestations on the skin. Finally, in extreme cases the disease was seen to affect the nervous system of the infected.