Septic shock is a result of a systemic response to infection, and can be a response to multiple infectious causes; septicemia may be present but septic shock can occur without septicemia.[5] The precipitating infections which may lead to septic shock if severe enough include, but are not limited to, appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, and mesenteric necrosis.[6][7]