His mother is from Bethlehem; his father, George John Hanania, from a prominent Christian family in Jerusalem, served with the U.S. Army during World War II and with the Office of Strategic Services (OSS), the predecessor of the CIA. He himself served with the U.S. Air Force during the Vietnam War and in the Illinois Air National Guard. Hanania's wife, Alison, is Jewish and has two children, one daughter from a prior marriage who is Catholic and one son from his current marriage who is Jewish; they live in Orland Park, Illinois.