Central venous catheters usually remain in place for a longer period than other venous access devices, especially when the reason for their use is longstanding (such as total parenteral nutrition in a chronically ill person). For such indications, a Hickman line, a PICC line, or a Port-a-Cath may be considered because of their smaller infection risk. Sterile technique is highly important here, as a line may serve as an entry point for pathogenic organisms.