SPAL played in the top flight league from 1920 to 1925, reaching the qualification playoff for the National Finals in 1921–22. From 1925 until the Second World War, they played in Serie B and Serie C: in this period, the club's all-time top striker Mario Romani scored 130 goals in 189 games during two different periods with the white-blues (1925–32 and 1937–38).