Its bishop, Eusebius took part in the Council of Ephesus in 431 and the Council of Chalcedon in 451. Another, Macarius, participated in the Council of Constantinople (869), which is seen within the Catholic Church as the eighth ecumenical council.[3][4][5] Although still documented at the end of the 14th century, it is no longer a residential bishopric. Accordingly, Clazomenae is today listed by the Catholic Church as a titular see.[6]