Beyond anti-amoebic therapies, there is also a role for topical steroids of anti-inflammatory medications in the treatment of Acanthamoeba keratitis. During infection, severe inflammation in the cornea and anterior chamber can cause more severe symptoms including pain and visual disturbance.[11] Topical steroids may be used to reduce this inflammation and thereby alleviate symptoms.[11][21] However, the role of steroids is typically very limited, because their dampening of the immune response may lead to worsening of the infection.[3][21] Additionally, steroids can increase the number of trophozoites in the cornea by inducing excystation.[30] Therefore it is typically recommended that steroids be used briefly to aid in symptom resolution, and that anti-amoebic agents be used both during, and for several weeks after topical steroid use.[15]