Trézéguet returned to training in early December 2015,[21] before making his competitive debut for Anderlecht on 27 December 2015 in a 2–1 victory over Westerlo when he replaced Dodi Lukebakio in the 82nd minute.[22] Following his debut, Hasi described him as having "great ability and the speed, and I can see a bright future for him."[23] He made his first start for the club a month later in a 2–0 defeat to Gent.[24] However, he was dropped from the side soon after with Hasi claiming that the language barrier was making it difficult for Trézéguet to understand the team's tactics, commenting "He is a diligent player and trains well with us so [...] but he rarely understands what we say,"[25] and that he was no longer considered the star player of the team as he had been with Al Ahly.[26]