In the "pain switch" concept (Davis et al., 2015), she emphasizes the basic feeling of "ouch" that must be represented by a core brain mechanism, regardless of pain intensity or quality. The other concept is called the Dynamic Pain Connectome [9][10] which emphasizes that spatiotemporal representation of pain in the brain is dynamic and includes activity in the salience and default mode network as well as the ascending nociceptive and antinociceptive pathways.