Alexander Hepburne Macklin OBE MC TD (1889 – 21 March 1967) was a British physician who served as one of the two surgeons on Sir Ernest Shackleton's Imperial Trans-Antarctic Expedition of 1914–1917. In 1921–1922, he joined the Shackleton–Rowett Expedition aboard the Quest. When Sir Ernest Shackleton advert came out in newspapers , the surgeon signed up as he had been on many ships as a surgeon.