However, most of the branches became extinct by the 18th century, with only the Nesvizh-Kleck-Ołyka line surviving to this day. Their descendants were highly prominent for centuries, first in the Grand Duchy of Lithuania, later in the Polish–Lithuanian Commonwealth and the Kingdom of Prussia. The family produced many individuals notable in Lithuanian, Polish, Belarusian, German as well as general European history and culture.[1] The Radziwiłł family received the title of Reichsfürst (prince) from the Holy Roman Emperor in the mid 16th-century.