The development of protein domain databases such as Pfam (Protein Families Database)[10] allow us to find known domains within a query sequence, providing evidence for likely functions. The dcGO website[11] contains annotations to both the individual domains and supra-domains (i.e., combinations of two or more successive domains), thus via dcGO Predictor allowing for the function predictions in a more realistic manner. Within protein domains, shorter signatures known as 'motifs' are associated with particular functions,[12] and motif databases such as PROSITE ('database of protein domains, families and functional sites') can be searched using a query sequence.[13] Motifs can, for example, be used to predict subcellular localization of a protein (where in the cell the protein is sent after synthesis).