Most populous urban areas in Southern Italy Naples Palermo Rank City Region Population Bari Catania 1 Naples Campania 955,503 2 Palermo Sicily 659,894 3 Bari Apulia 319,482 4 Catania Sicily 311,777 5 Messina Sicily 231,708 6 Taranto Apulia 195,279 7 Reggio Calabria Calabria 179,049 8 Cagliari Sardinia 154,108 9 Foggia Apulia 150,185 10 Salerno Campania 132,640 Sources: 2019 Demo Istat[39]