The reserve is bordered with Sakaka governorate and Domat al-Jandal in the eastern, Tabuk to the west, Tayma to the southwest, Hail to the southeast, and the Jordanian border to the north. The reserve is located within four administrative regions, which are Al-Jawf region, Hail region, Tabuk region, and the northern border. Several governorates and villages are located within the reserve borders, the most prominent of which are: Al-Qurayyat and Tabarjal in Al-Jawf region, and Tarif in the northern border region.