Blood sugar levels are reflected in salivary gland secretions. High salivary glucose (HSG) levels are a glucose concentration ≥ 1.0 mg/d, n = 175) and those with low salivary glucose (LSG) levels are < 0.1 mg/dL n = 2,537). Salivary gland secretions containing high levels of sugar change the oral microbiome and contributes to an environment that is conductive to the formation of dental caries and gingivitis.[6]