This type of communication can make it difficult for doctors to understand the true gravity of a symptom, which may lead to misdiagnosis. Furthermore, doctors and scientists need to be especially aware of the negative implications that hyperbole can have in medical discourses. As Joseph Loscalzo points out in his article Clinical Trials in Cardiovascular Medicine in an Era of Marginal Benefit, Bias, and Hyperbole, the use of hyperbole by investigators during medical trials can “often prejudice the trialist in favor of a positive result.”[54] When investigators provide trialists with bias, whether intentionally or unintentionally, the data that is collected may be skewed in the direction of the bias provided by the investigator.