In addition to the thyroid gland, Vitamin D plays a crucial role in the absorption of calcium.[1] In fact, Vitamin D is needed for efficient absorption of calcium and therefore proper bone health.[2] Vitamin D is a fat-soluble vitamin, as well, it is unique because it is considered as a hormone; synthesized endogenously in the liver in form of Cholecalciferol.[2] The endogenous inactive form of Vitamin D is Cholecalciferol or Vitamin D3 which is converted to active form of Vitamin D–Calcitriol also known as 1, 25-Dihydroxycholecalciferol in the Kidney upon exposure to UV ray of sun light.[2] Deficiency in Vitamin D or renal disease contributes to bone disorder such as in Osteomalacia in adult and Rickets in children.[2] Osteomalacia is the softening of bones due to poor bone mineralization which is in turn due to poor calcium absorption.[2] Ultimately, these hormonal changes in body; such as function of thyroid, parathyroid, liver and kidney disrupts metabolic changes as well as function of specific organs, which in turn leads to condition that are not desirable such as bone disorders or other endocrine related diseases.[2]