Indeloxazine (INN) (Elen, Noin) is an antidepressant and cerebral activator[1][2] that was marketed in Japan and South Korea by Yamanouchi Pharmaceutical Co., Ltd for the treatment of psychiatric symptoms associated with cerebrovascular diseases, namely depression resulting from stroke, emotional disturbance, and avolition.[3][4] It was marketed from 1988[4] to 1998, when it was removed from the market reportedly for lack of effectiveness.[5]