Yudkin's publications from the Department showed an unusual breadth of interests, including (in addition to biochemistry) further studies of adaptive enzymes,[18][19] nutrition and public health,[20] diseases of affluence,[21][22] food choice both in human beings[23][24] and in experimental animals,[25] and historical aspects of the human diet.[26][27] But his concern became increasingly focused on two topics: the treatment of overweight and the harmful effects of excessive sugar (sucrose) consumption.