In the quarter-finals, the club won 6–4 on aggregate. The first game of the semi-finals, against the UANL Tigres at the Estadio Universitario, ended in a 1–1 draw and Santos won the second game to advance to the final. After playing Monterrey to a 1–1 draw at Estadio Tecnologico, Santos Laguna won the second game 2–1 with goals by Daniel Ludueña and Oribe Peralta for the club's fourth title.