The post-operative complications occurred included seroma, wound dehiscence, hematoma; whereas partial NAC necrosis occurred in 10 per cent of the reduced breasts; yet, after refinement of the Lejour technique, the study Vertical Mammaplasty: Early Complications After 250 Personal Consecutive Cases (1999), reported a reduced incidence rate of 7.0 per cent in the 324 breast reductions performed in 167 patients.[28] Moreover, the incidence of such post-operative complications is greater among the women whose breasts required large-volume resection of the parenchyma; in women who were obese; in women who were tobacco smokers; and in young women.[29][30] Furthermore, wound dehiscence, epidermolysis, adipose tissue necrosis, and infection occur less among women who undergo Lejour-technique breast reduction, than among women who undergo a periareolar, anchor pattern breast-reduction, or an inferior-pedicle breast reduction. Nonetheless, bottom-edge asymmetry occurs more among Lejour-technique patients; the revision surgery rates can be up to 10 per cent. Moreover, the liposuctioning of the breast does not increase the rate of local medical complications; decreased NAC sensitivity occurs in 10 per cent of the women; and total NAC insensitivity occurs in 1.0 per cent of women.[31]