The magazine has published works by a number of well-known manga artists, including Osamu Tezuka, Shotaro Ishinomori, Sanpei Shirato, Takao Saito, Fujiko Fujio (A), Fujiko F. Fujio, and Tetsuya Chiba. Big Comic also serializes Saito's Golgo 13, which is the oldest manga series still in publication.