Although the injury is typically associated with vaccination, it can also occur as the result of any other kind of injection into the shoulder area. However, examination of injury reports suggests that this type of injury is of increased severity when administration of a vaccine is involved, which "may be due either to the antigenic or nonantigenic components of the vaccine".[4] In order to avoid this type of injury, injection administrators are advised to avoid injecting the patient too high, too low, or too far to the side, and to avoid using needles that fail to penetrate deeply into the muscle, or that penetrate too deeply and contact the bone.[3]