Hossenfelder's research interest is in the phenomenology of quantum gravity.[1] She focuses on the role of Lorentz invariance and locality, which would be altered in the discovery of quantum gravity.[11] Hossenfelder is trying to find experimental evidence of quantum gravity.[14][15][16][17] Since 2007 she has been involved with the annual conference series "Experimental Search for Quantum Gravity".[18] Hossenfelder has created a number of YouTube videos exploring the topic.[19][20][21] She has been employed by the Frankfurt Institute for Advanced Studies since 2015, where she leads the Analog Systems for Gravity Duals group.[22] Another area of her research is foundations of quantum mechanics, where she has argued against free will and in favor of superdeterminism.[23][24]