The town extends along the river Agno, from which Valdagno takes its name, and the homonymous valley surrounded by hills; the Piccole Dolomiti and the Alti Lessini. The presence of the river Agno influenced both the town origins and its development; in particular, it provided water to the population, increasing industrial activities especially in the textile area. The valley has a west–east orientation, allowing wind currents from the Adriatic Sea to cause climate consequences.