After returning home from a trip to Europe, Lane died in Lynchburg, Virginia on March 15, 1909, while travelling to Asheville, North Carolina to recuperate from illness. Her home was at that time in Port Deposit, Maryland, where her husband was director of the Tome School.[10][11] According to a report in the Book News Monthly after her death, she had been ill for some years and her death was not wholly unexpected. She reportedly had to write in an "absolutely dark room, with her head tightly bandaged, her writing managed only by a careful guiding of her pencil over the paper."[12][13][14]