The risks associated with this syndrome include a strong tendency of developing cancer in a number of parts of the body.[5] While the hamartomatous polyps themselves only have a small malignant potential (<3% - OHCM), patients with the syndrome have an increased risk of developing carcinomas of the pancreas,[6] liver, lungs, breast, ovaries, uterus, testes and other organs. Specifically, it is associated with an increased risk of sex-cord stromal tumor with annular tubules in the ovaries.[7]