He served as Minister for Defence Production and Minister for Science and Technology, in Abbasi cabinet from 2017 to 2018. Previously he served as the Minister for Defence Production[4] and the Minister for Science and Technology in the Third Sharif ministry.[2][5] A leader of the Pakistan Muslim League (N), Hussain previously briefly held the cabinet portfolio of Minister for Defence Production during the Gillani ministry in 2008.[6][7]