The palace came to be used as a residence and two additional major wings were built towards the piazza, frescoes were added and a hanging garden was built. It was in this Palace that in 1591 a commission of eight cardinals met to revise the Bible for a printed edition, among them cardinal Marcantonio Colonna and Saint Robert Bellarmine. The building is characterized by frescoes painted by mannerist artists of the 16th century, attributed to Dutch painters, to Antonio Tempesta, and to the Zuccaris (Taddeo Zuccari and Federico Zuccari).