Whether trypophobia is associated with obsessive–compulsive disorder (OCD) has also been studied, but a significant minority of those with trypophobia meet the DSM-5 criteria for obsessive–compulsive disorder.[1] Martínez-Aguayo et al. stated that other findings refer to trypophobia having common comorbid psychiatric diagnosis, such as major depressive disorder or generalized anxiety disorder, although Le et al. felt that general anxiety does not cause trypophobia.[3]