Etravine has been studied for use in a drug repositioning application. In a paper[12] published in the medical publication Movement Disorders, Etravirine was shown to affect an increase in frataxin production. Frataxin deficiency is a key component to Friedreich's ataxia, a genetically inherited disease that causes the progressive loss of coordination and muscle strength leading to motor incapacitation and the full-time use of a wheelchair.