A 48-year-old man with possible underlying myopathy was uneventfully treated with ezetimibe 10 mg/day and rosuvastatin 5 mg every other day for 17 months. After three weeks of drinking 200ml pomegranate juice twice a week, he presented urgently with thigh pain and an elevated serum creatine kinase level indicating rhabdomyolysis. Doctors suspected competitive inhibition of P450 enzymes in the liver by the pomegranate juice (much like grapefruit juice).