This compound has also been successfully used as a treatment for aortic valve stenosis,[10] erythromelalgia,[11] oesophageal varices,[12] severe pyrexia (fever),[13] lactic acidosis,[14] myocardial infarction,[15] neuroleptic malignant syndrome,[16] pulmonary hypertension,[17][18][19] respiratory distress syndrome in the newborn,[20][21] shock,[21] cerebral vasospasm,[22][23] ergot toxicity,[24][25][26][27] and ventricular septal defects.[28]