Acetylesterase (EC 3.1.1.6), splits off acetyl groups Cholinesterase Acetylcholinesterase, inactivates the neurotransmitter acetylcholine Pseudocholinesterase, broad substrate specificity, found in the blood plasma and in the liver Pectinesterase (EC 3.1.1.11), clarifies fruit juices EC 3.1.2: Thiolester hydrolases Thioesterase Ubiquitin carboxy-terminal hydrolase L1 EC 3.1.3: Phosphoric monoester hydrolases Phosphatase (EC 3.1.3.x), hydrolyses phosphoric acid monoesters into a phosphate ion and an alcohol Alkaline phosphatase, removes phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. Phosphodiesterase (PDE), inactivates the second messenger cAMP cGMP specific phosphodiesterase type 5, is inhibited by Sildenafil (Viagra) Fructose bisphosphatase (3.1.3.11), converts fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis EC 3.1.4: Phosphoric diester hydrolases EC 3.1.5: Triphosphoric monoester hydrolases EC 3.1.6: Sulfuric ester hydrolases (sulfatases) EC 3.1.7: Diphosphoric monoester hydrolases EC 3.1.8: Phosphoric triester hydrolases Exonucleases (deoxyribonucleases and ribonucleases) EC 3.1.11: Exodeoxyribonucleases producing 5'-phosphomonoesters EC 3.1.13: Exoribonucleases producing 5'-phosphomonoesters EC 3.1.14: Exoribonucleases producing 3'-phosphomonoesters EC 3.1.15: Exonucleases active with either ribo- or deoxy- Endonucleases (deoxyribonucleases and ribonucleases) Endodeoxyribonuclease Endoribonuclease either deoxy- or ribo-