Wildlife is one of the important components of the high biodiversity in this reserve. Among the main values of the Sierra de Manantlán, in addition to its great wealth of species and its unique biogeographical characteristics, particular mention should be made of the presence of endangered or useful endemic species. So far 110 mammal species have been reported, including the Mexican vole subspecies Microtus mexicanus neveriae, the pocket gopher Cratogeomys gymnurus russelli, the oncilla, jaguarandi, ocelot, puma, bobcat, jaguar and four species of nectarivorous bats.