Additionally, the injection of talc has been associated with pulmonary talcosis in intravenous drug users.[15] Wheel filters are the most effective filters.[16] 5.0 micron wheel filter (e.g., Apothicom Sterifilt)—now shared in some needle exchange programs instead of cotton—is intended to get rid of the talc from prescription tablets like benzodiazepines, dextroamphetamine, methadone tablets, and other recreational drugs like MDMA. However, cotton wool (with the risk of cotton fever) or tampons can be used, although to be more effective, several filtrations should be performed; cigarette filters should not be used, due to the risk of fibres breaking off and being injected along with the solution, nor should filters of any sort ever be re-used, either as filters or in an attempt to recover drug material present, due to many risks, ranging from cotton fever to life-threatening sepsis.[14]