Age > 55 years Blood levels: PO2 Oxygen < 60mmHg or 7.9kPa White blood cells > 15 Calcium < 2 mmol/L Urea > 16 mmol/L Lactate dehydrogenase (LDH) > 600iu/L Aspartate transaminase (AST) > 200iu/L Albumin < 32g/L Glucose > 10 mmol/L