Donepezil was approved for medical use in the United States in 1996.[1] It is available as a generic medication.[2] In the United Kingdom a typical months supply costs the NHS about £8.44 as of 2019.[4] The wholesale cost of this amount in the United States is about US$1.38. [5] In 2016 it was the 98th most prescribed medication in the United States with more than 7 million prescriptions.[6]