Arthur Conan Doyle, the creator of the fictional detective Sherlock Holmes, started his career as a writer in Birmingham.[74] His first story "The Mystery of Sasassa Valley" was written and published in 1879 while he was working as a medical assistant in Aston, as was his second "The American's Tale", whose success led his editor to advise him to give up medicine and pursue a full-time literary career.[75] Birmingham appears in Conan Doyle's early stories as Birchespool,[76] and several of Conan Doyle's later Sherlock Holmes stories, including "The Adventure of the Stockbroker's Clerk" and "The Adventure of the Three Garridebs", have explicit Birmingham settings.[77]