Advocates tout various treatments for "leaky gut syndrome", such as dietary supplements, probiotics, herbal remedies, gluten-free foods, and low-FODMAP, low-sugar, or antifungal diets, but there is little evidence that the treatments offered are of benefit.[1] None have been adequately tested to determine if they are safe and effective for this purpose.[3] The U.K. National Institute for Health and Care Excellence (NICE) does not recommend the use of special diets to manage the main symptoms of autism.[1]