In medicine, Clarke's test is a component of knee examination which may be used to test for patellofemoral pain syndrome, Chondromalacia Patellae, Patellofemoral Arthritis, or anterior knee pain. It is not a standard part of the knee examination but is used to diagnose anterior knee pain where the history indicates this as the likely pathology. The patient is asked to actively contract the quadriceps muscle while the examiner's hand exerts pressure on the superior pole of the patella, so trying to prevent the proximal movement of the patella.