Depressed individuals have a shorter life expectancy than those without depression, in part because depressed patients are at risk of dying of suicide.[249] However, they also have a higher rate of dying from other causes,[250] being more susceptible to medical conditions such as heart disease.[3] Up to 60% of people who die of suicide have a mood disorder such as major depression, and the risk is especially high if a person has a marked sense of hopelessness or has both depression and borderline personality disorder.[252] The lifetime risk of suicide associated with a diagnosis of major depression in the US is estimated at 3.4%, which averages two highly disparate figures of almost 7% for men and 1% for women[253] (although suicide attempts are more frequent in women).[254] The estimate is substantially lower than a previously accepted figure of 15%, which had been derived from older studies of hospitalized patients.[255]