MRE was first described by Muthupillai et al. in 1995.[3] Because diseased tissues are often stiffer than the surrounding normal tissue, MRE has been applied to visualize a variety of disease processes which affect tissue stiffness in the liver, breast, brain, heart, and skeletal muscle.[1][4] For example, breast tumors are much harder than healthy fibroglandular tissue.[5] MRE is similar to palpation; however, whereas palpation is a qualitative technique performed by physicians, MRE is a quantitative technique performed with a radiologist.[1]