Wright later pioneered combinatorial work in chemotherapeutics, focusing not simply on administering multiple drugs, but sequential and dosage variations to increase the effectiveness of chemotherapy and minimize side effects.[2] She was successful in identifying treatments for both breast and skin cancer, developing a chemotherapy protocol that increased skin cancer patient lifespans up to ten years.[2] She also developed a non-surgical method, using a catheter system, to deliver potent drugs to tumors located deep within the body such as the liver and spleen.