Summary of the Symptoms Present in 2 Siblings Suffering from COACH Syndrome in 1974 Symptom Sibling 1 Sibling 2 Mastoiditis and sinusitis Yes Yes Dermatolglypics No Yes Extra finger No Yes Low hairline No Yes Ptosis of eyes No Yes High palate Yes Yes 'Carp'- shaped mouth Yes Yes Short middle 3 toes Yes No Flat nose No Yes Abnormal or underdeveloped ears Yes Yes Anteverted nostrils Yes Yes Perinatal complications Yes Yes Pronounced forehead Yes Yes Hypertelorism of eyes Yes Yes Strabismus Yes Yes Nystagmus Yes Yes Decreased muscle Yes Yes Slurred speech Yes No Irregular movements Yes Yes Ataxia Yes Yes Intellectual deficit Yes Yes Coloboma of the eye Yes Yes Renal anomalities Yes Yes Hepatic fibrosis Yes Yes