The net reaction for the reaction catalyzed by nitric oxide dioxygenase is shown below:* 2NO + 2O2 + NAD(P)H → 2NO3− + NAD(P)+ + H+Nitric oxide is a ubiquitous small molecule that is integrated in a wide variety of physiological processes including smooth muscle vasodilation, platelet disaggregation, neurotransmission, and immune response to bacterial infection.