Sentence 1: This is due to the reduction of excitatory synaptic transmission in a nucleus and the increased excitability in the motor neurons caused by nicotine activation .
Sentence 2: This is due to the reduction of nicotine transmission in a nucleus and increased excitability in the motor neurons caused by an excitatory synaptic activation .
Question: Do Sentence 1 and Sentence 2 express the same meaning? Yes or No?