Passage: The common treatment for phyllodes is wide local excision.  Other than surgery, there is no cure for phyllodes, as chemotherapy and radiation therapy are not effective.  The risk of developing local recurrence or metastases is related to the  histologic grade, according to the above-named features. Despite wide excision, a very high percentage of surgeries yielded incomplete excision margins that required revision surgery. Radiation treatment after breast-conserving surgery with negative margins may significantly reduce the

Question: Why is there no cure for phyllodes other than surgery?
chemotherapy and radiation therapy are not effective