Passage: Because of the high reactivity of the metal, toxicological data are available only for compounds. Soluble barium compounds are poisonous. In low doses, barium ions act as a muscle stimulant, and higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, shortness of breath, and paralysis. This toxicity may be caused by Ba2+ blocking potassium ion channels, which are critical to the proper function of the nervous system. Other organs damaged by water-soluble barium compounds (i.e., barium ions) are the eyes, immune system, heart, respiratory system, and skin causing, for example, blindness and sensitization.Barium is not carcinogenic and does not bioaccumulate. Inhaled dust containing insoluble barium compounds can accumulate in the lungs, causing a benign condition called baritosis. The insoluble sulfate is nontoxic and is not classified as a dangerous goods in transport regulations.To avoid a potentially vigorous chemical reaction, barium metal is kept in an argon atmosphere or under mineral oils. Contact with air is dangerous and may cause ignition. Moisture, friction, heat, sparks, flames, shocks, static electricity, and exposure to oxidizers and acids should be avoided. Anything that may contact with barium should be electrically grounded. Anyone who works with the metal should wear pre-cleaned non-sparking shoes, flame-resistant rubber clothes, rubber gloves, apron, goggles, and a gas mask. Smoking in the working area is forbidden. Thorough washing is required after handling barium.

Question: What is one symptom of a high dose of barium?
tremors