Imagine a question and stream-of-consciousness explanation for which this is the answer: yes
Question: Did the death of Helen Palmer have a significant effect on Dr. Seuss?
Stream-of-consciousness: Dr. Seuss's real name was Theodor Geisel. Theodor Geisel was married to Helen Palmer at the time of her suicide. Theodor Geisel is quoted having said he considered suicide after the death of his wife.