Article: Your hormones have a lot to do with your monthly period, so it is important to take your cycle into account when beginning to use the cream to raise your progesterone levels. Your hormones are working as a team to trigger ovulation, so it's important to help balance the hormones.  You can chart your cycle by identifying the expected first day of your next period, then counting backwards two weeks (14 days) from then. This would be day 14 for a woman with a cycle duration of 28 days, or day 21 for another woman with a cycle duration of 35 days. The exact day will differ from woman to woman according to her calculations and and her cycle's usual duration. Generally, you will want to apply the cream twice a day, unless instructed otherwise by your doctor. Since you will likely want to apply the cream at home (so you don't have to tote it to work), you should choose two times when you are generally at home. Try to apply once in the morning, after your shower, and once at night, before bedtime. As with any medication or supplement, it can be very helpful to get into a routine when applying your progesterone cream. Make it a habit to apply your cream at the same time each day. Soon, the application will be second nature, and you will be less likely to forget a dose. If you learn that you are pregnant while using the cream, keep applying your normal doses. It is important that your progesterone levels do not drop early in a pregnancy, as that could result in loss of the fetus. Make sure to consult your doctor before you stop applying the cream.

What is a summary?
Calculate your menstrual cycle. Pick the right time of day. Be consistent. Keep applying the cream if you become pregnant.