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Plug this in before you launch CFG USB loader for the first time. Use the bottom USB port on the back of the Wii. If you're prompted by your Wii to format the drive, select "Cancel." If you click "Format," you'll need to go back and format it as FAT32 again. Select "Load" to start the program. This will set CFG to load backups from your USB drive. When prompted to select your partition, you should only have one available. Select it to continue. This will launch the USB loader with your settings. You'll want to save your device and IOS settings so you're not prompted for them each time you start:  Point at the bottom of the screen to open the menu. Select "Settings" and then "System." Select "Save Settings." You can copy any Wii or GameCube game by using the CFG USB Loader. Insert the disc and it will appear in the Loader program. You'll be using this homebrew program to rip the games from your Wii and GameCube discs to your USB drive. This will open the installation screen for the game that is inserted. This will begin copying the game files to your USB drive. This may take a while to complete, especially for newer, larger games. Once you have some games installed, they'll appear in the main CFG Loader window. Select one to view details and launch it. With the game selected, press "A" to start playing. You'll see some text as the game loads, and then it will start. You can keep installing games from any disc, legitimate or burned. All of the games will be added to your USB drive, and you won't need the discs to play them.

Summary:
Plug your formatted external drive or USB drive into your Wii. Open the Homebrew Channel and select "Configurable USB Loader." Select "USB" when prompted. Ensure IOS 248 is selected and start the program. Save your settings. Insert a disc that you want to copy into your Wii. Open Configurable USB Loader if it isn't already. Press "+" in the CFG main menu. Click "Install." Select an installed game in CFG Loader. Press "A" to launch the game. Continue installing games.