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Fill two clean socks with clean cat litter. Place the cat litter filled socks into your shoes. Leave the socks in your shoes overnight.

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To prevent the cat litter from spilling inside or around your shoes, you should tie off the top of each litter filled sock with a simple knot. You can also put cat litter directly into your shoes, though litter can sometimes get caught in the crevices of your shoe and cause you discomfort later on.  In place of socks, you could also use pantyhose. The thin material of these will form less of a barrier between the odor fighting elements of the litter and the bad smelling parts of your shoe.  To give your cat litter a little more punch, you might consider adding some baking soda to it. Simply add a heaping spoonful to each sock, tie each off at the top, and shake or massage the socks to distribute the baking soda. If you notice that your socks cause your shoes to deform or otherwise change shape, you may want to remove some litter from the socks. You'll be leaving the litter filled sock in your shoes for a long period of time, and a sock that is too full might alter the shape of your shoe. If you find that your socks are too full, hold your socks over a garbage can while unknotting the tops. This way, stray litter will be contained in the garbage, preventing a mess. In most cases, it should only take a night for the odor fighting properties of the cat litter to eliminate the smell. Especially bad cases, however, might take more time. You can check the odor of your shoes by removing the sock briefly and smelling the shoe. If you notice a lingering odor, you should leave the litter filled socks in the shoe for longer.  Once the odor is removed from your shoes, you can throw away the cat litter and wash the socks as you would normally. If the cat litter is still good enough to use in a litter box, you may want to reuse the litter there. Give your shoes a thorough inspection after you've removed the litter filled socks. Small pieces of litter can sometimes push through the fabric of the sock and become an irritant later when you wear the shoes.