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To do this, copy the ESEBLCI2 dll files from the Exchange 2003 install CD to the EXCHSRVR\BIN folder on the  backup server. Add the key "HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\BackupRestore\DLLPaths  REG_EXPAND_SZ - esebcli2 - c:\exchsrvr\bin\esebcli2.dll" to the registry. From NTBACKUP, select "remote store" under "tools."  " Select a folder to save the backup to and give the backup a name. Decide whether to verify the data after the backup. This will take longer, but ensures a successful backup. It will show what percentage is complete as it runs. Check the event log to see if it was there were any errors during the process.

Summary:
Install Exchange System Manager on the backup server or modify the server to back up a remote Exchange server. Press the start key and select run. Type the command "NTBACKUP. Follow the prompts to the next screen. Wait for the backup to run.