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Choose a quiet, calm location for your guinea pig’s cage. Buy a cage that is large enough for your guinea pig. Add bedding to the cage. Place toys and hutches into the cage. Talk to your guinea pig.

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When your guinea pig first arrives in your home, it is likely to be overwhelmed and scared. A secure, calm, and quiet space will help your guinea pig begin to feel safe in its new environment.  Keep your guinea pig away from other pets, small children, and loud noises. A quiet space will help to prevent the guinea pig from becoming startled or scared. If possible, place your guinea pig’s cage in a room that can be completely shut off. This way you can occasionally open the cage and let your guinea pig have playtime. Give your guinea pig some time to adjust to its new home. Avoid handling it for up to 3 days after you bring it home to help it settle in. The minimum recommended cage size for 1-2 guinea pigs is 7.5 square feet (2.3 m). Add 1.5 square feet (.46m) for each additional guinea pig. There should be plenty of room for the guinea pig to run; if you add a lot of ramps or accessories, you may need to go to a larger size.  The base of the cage should be a solid surface. Guinea pigs may get their paws stuck and injure themselves if the floor of the cage is made of wire or mesh. A solid plastic floor is safer and will be easy to clean. That said, no matter what type of cage you get, you will need a thick layer of bedding to protect your guinea pig's feet. Look for cages that are easy to clean and maintain. You should be able to easily reach all areas of the cage. You should also look for cages made from easily cleanable materials, such as plastic. Metal cages are also acceptable, but be aware that they may rust and need to be replaced. Hay, paper, towels, and woodchips can all serve as bedding for your guinea pig. Most pet stores sell wood shavings which are also a popular form of bedding. Remember to  change the bedding about once every week.  Never add damp or wet bedding as it can grow mold. Avoid using sawdust or straw as bedding as they can also mold easily. Cedar and pine shavings can be toxic to guinea pigs, so look carefully at the type of wood shavings you are using as bedding. These will help the guinea pig to feel comfortable. Huts and igloos provide a place where the guinea pig can hide and feel safe when they are overwhelmed. They can be purchased online or at your local pet store. Consider adding toys, such as balls, ramps, or cardboard tubes to provide entertainment for your guinea pig. Speaking to your guinea pig will help them get used to your voice. When you feed them, clean the cage, or change their water, talk to them in a calm tone. You should also visit your guinea pig and speak to them throughout the day so that they begin to get used to your presence.