Now eventually, as we continue to increase our temperature, the hydrogen bonds that hold all these secondary structures will also break. And so these different secondary structures will eventually break down denature until we form a single long polypeptide in its linear state. So now we only have the primary structure. And so notice as we go from the native state to our denatured state, these interactions take place cooperatively. And not only that, but we also go through these intermediate states. And so what that means is during the folding or unfolding process, going this way is unfolding, going this way in reverse, is folding.