And what this complex basically does is it takes the pyruvate, it uses two Cofactors, one NAD plus and one coenzyme A, or simply COA, to transform the pyruvate into acetyl coenzyme A. So basically, the pyruvate is decarboxylated to produce our Co to the carbon dioxide. And then the remaining two carbon molecule mixes with the coenzyme A to produce acetyl coenzyme A. And we also reduce our NAD into NADH and we form the hion. So basically, these are the products and these are the reactants of the pyruvate decarboxylation process that takes place within the mitochondrial matrix. Now, because we form two pyruvate molecules, when we break down one glucose, these two pyruvate molecules will both undergo the decarboxylation reaction.