And what this equation basically tells us is if we take the enzyme so this is the red enzyme and we add the substrate so given in blue, then what will begin to happen is some the substrate will begin to bind onto the active side to form the enzyme substrate complex. And this is our intermediate. Now, what we also said was we assumed the steady state condition and the steady state condition means that the concentration of this intermediate, the enzyme substrate complex, is not changing over time. So the concentration of this remains the same even though this concentration and this can actually change over time. And by making that steady state assumption, we were able to basically create the following Michael's constant. So Km, we said, was equal to K minus one plus K two divided by K one, where K minus one is simply the rate constant for this reaction, the dissociation of the enzyme substrate complex back into the enzyme and the substrate.