And once this complex is formed, that will essentially inhibit or block the activity of that enzyme. And this type of inhibition is known as uncompetitive inhibition. So in some cases, the binding and the substance to the active side changes the confirmation of the enzyme and creates a brand new pocket we call an allosteric side that was not previously there. And this pocket is only created when the green substrate binds into the pocket of this blue enzyme. So before the binding took place, we did not have that allosteric site. But once the binding takes place, we create this pocket, the crevice, that can now bind some type of inhibitor molecule.