We discussed protein kinasea and Cammodulen, so calm dependent protein kinases. And we said in this particular cascade and we used the physiological effect of decreasing or increasing blood pressure. We said that these two types of kinases are basically crucial for allowing that smooth muscle in the cardiovascular system to actually contract. And so what these do is they stimulate the breakdown of Glycogen and they stimulate the contraction of those smooth muscles which also depend on ATP to basically contract. Now, in the case of insulin signaling, we said that insulin signaling is basically used once we ingest a carbohydrate rich meal. So once we ingest all these carbohydrates, the glucose concentration in our blood plasma increases.