But in uncompetitive, the inhibitor can only bind to our site on that enzyme when the substrate actually binds to our active site. In fact, in uncompetitive inhibition, when the substrate, shown in blue binds to the active site of the enzyme here, when that binding takes place, only then do we create that site for this inhibitor. So we can imagine this binds, then it creates that site for our inhibitor, shown in purple, that can then bind to that site to form this enzyme substrate inhibitor complex. So that's the major difference between non competitive and non competitive. So in this inhibitor process, the inhibitor only binds to the enzyme once the substrate is actually bound to that enzyme. And once it binds, it basically deactivates that enzyme.