Now, once we form this complex, only now can we actually transform the Pyruvate into lactate and the NADH into the NAD plus. And once we form the two products, so lactate in this case is product C and NAD plus E is product D. Once we form these two products, only then can they be released from the active side of that enzyme. And because this is an ordered sequential reaction, the order at which these two products are released also matters. And in this particular reaction, we're always going to find that it's the lactate that leaves first, followed by that NAD plus molecule. So in an order sequential reaction, to actually catalyze the transformation of the reactants into the products, we have to form the termary structure, this complex in which the active site contains those two substrates. And we also have to basically bind these two reactants into the active site in a specific order.