While this is the loop, they contain the mismatched nucleotides and that means they cannot interact and so they will destabilize this localized region of space in our RNA molecule. Now, just like in proteins we have this tertiary structure and secondary structure. RNA molecules can also form secondary and tertiary structures. So when nucleotides found in close proximity along that particular polynucleotide chain interact via these hydrogen bonds between the nucleotide bases that can form a secondary structure. In fact when we have these nucleotides down far away interacting via these base pairings then that can form tertiary structure. So just like proteins contain this secondary and tertiary structure because these bases along the polynucleotide chain of the RNA molecule can interact with one another RNA molecules can also form secondary and tertiary structure.