So in this case, a segment of chromosome 21 basically detaches and moves on to this non homologous chromosome. So remember, these are non homologous chromosomes with respect to one another. So we have a breakage of a segment of that DNA take place here and this basically moves on to this chromosome right over here. And so what we form is this larger abnormal chromosome. And the way that we call it is because we have a fusion of a segment of 21 onto 14, we call this chromosome 1421. So a segment of DNA on chromosome 21 can basically break off and reattach onto a non homologous chromosome, chromosome 14.