And so the highest possible value that can be achieved by KCAD divided by Km is equal to k one. And mathematically, this is how we express that. So if we take the limit as k minus one, this approaches zero. So if we plug in a zero here, this divided by this gives us one, and the limit is simply equal to K one. And what that means is that physical limit that determines how high this ratio can get is basically the rate constant for this reaction, where K one is simply the rate constant that describes the formation of that enzyme substrate complex. So the limiting fact that that basically limits how high this ratio can get is how quickly we actually form that enzyme substrate complex in the first place.