And now the antigen is found inside this vesicle of arocytoplasm. Now the cell also has lysosomes and these lysosomes are shown in green and they confuse with this vesicle. And these lysosomes release digestive enzymes that can proteolytically break down our antigen. So the antigen begins to break down and a small portion of that antigen known as the antigenic determinant or the epitope is taking and placed on the same type of protein complex that was found on the macrophage MHC class two major histocompatibility complex, class two. So we have the antigen, we have our MHC class two complex on our B cell. What happens next?