And it's Fibrin that actually binds together to form that mesh like network within a rupture and that seals off that rupture. So basically the Fibrin, with the help of this protein, factor 13, which is also activated by Thrombin, the Fibrin can form these covalent bonds between other adjacent fibrin proteins. And so we eventually form these blood clots. So Thrombin not only activates platelets and calls upon platelets, it also forms Fibrin and it activates factor 13 that is needed to form the covalent bonds between many of these adjacent Fibrin that lie along that rupture. So we see that the final pathway consists of the following. When factor ten is activated by either the extrinsic or the intrinsic pathway, it combines with factor five to form a dimer complex we call prothrombinase.