So if we examine this curve, the red curve describes this initial curve and the blue curve describes a few days following the exposure to high altitude. And that's when the concentration of two three BPG increases. So by increasing two three BPG, we basically shift the entire curve to the right side and that decreases definitive of hemoglobin for oxygen. And what that means is if hemoglobin is less likely to be bound to oxygen at a partial pressure of 20 mercury, which is the partial pressure inside our exercising tissue, this point on the blue curve will have a lower Y value than the red curve. And what that means is more of the hemoglobin will basically unload and release that oxygen to the tissue. So the red curve describes a Y coordinate of, let's say about 00:32.