So we said a specific type of effective molecule known as cyclic adenosine monophosphate has to actually bind to the PKA molecule protein Kindness A to actually activate that. And this is our method of allosteric regulation. So proteolytic AC cleavage was discussed in this section. And it basically involves an irreversible process that usually does not require energy. And what happens is Arozymogen inactive enzyme is transformed into its active via the process of hydrolysis of one or several peptide bonds. And the final method of regulation that we focused on was reversible covalent modification.