Well, notice that reaction one and two are before this cycle actually takes place. So if we just follow this circular arrow here, if we have a problem here or here, it's before the cycle takes place. And so by replacing any one of these intermediates citrulline, this molecule Arginine, this molecule that will do nothing in a person with carbon oil phosphate deficiency or, ornithine transcarbol deficiency. And so what will help? Well, again, we have to limit the total protein intake because that will decrease amino acid metabolism and decrease the ammonia production. But more importantly, what we have to do is we have to somehow rid the body of glutamine as well as glycine.