And this is given by this equation. Now, if we take a look at the following curve when exactly under what conditions will the blue curve actually reach the maximum velocity? Well, notice as we increase the concentration, this blue curve essentially reaches or approaches that maximum velocity asymptotically. And what that means is if we continually increase the concentration of S, the substrate, it will eventually approach and reach very closely the maximum velocity of that enzyme mixture. And so what we see happen is when the concentration of the substrate is very high, that is when the value of S, the concentration of substrate is much greater than the Km value for that enzyme mixture, we see that our blue curve will essentially reach that maximum velocity. Now remember, Km is basically the concentration of the substrate at which the enzyme operates at exactly half of the maximum velocity.