So ultimately, what the cell has to do is somehow remove the GTP and bind the GDP Guanosine diphosphate. Because once the Guanosine diphosphate binds onto the alphagy protein, that will cause a decrease in the affinity of the alphagy protein for that cyclist and that will cause it to actually detach, terminating this cyclist's ability to form those cyclic adenosine monophosphate molecules. So it turns out that this alphagy protein actually has a built in timer. A few seconds to a few minutes following the activation of the alphae protein by the attachment of the GTP, the alphagy protein itself can actually take a water molecule from the cytoplasmic environment and use that water molecule to hydrolyze the GTP back into GDP. And as soon as that takes place, as soon as we replace the GTP in place a GDP, that will decrease the affinity of the alphagy protein for the cyclist, causing it to dissociate from that cyclist. And once it dissociates, it goes out and finds those beta and gamma units to basically reform this primer molecule.