So instead the phosphorylated IRS. So instead of activating anything, they phosphorylates the phosphorylated. IRS basically acts as an attachment point for a lipid kinase. And remember, lipid kinases are protein kinase that take a phosphoryl group from ATP and they move it onto some type of fat molecule, some type of lipid molecule. And to be more specific, the lipid kinase that this actually attaches to is known as phosphonosatide three kinase. So we have the phosphorylation of these four residues on this iris molecule causes this molecule here, phosphorositi Three kinase to actually attach.