Now, what exactly is our starting point? Well, the starting point is right here. So we essentially begin by studying how that enzyme is functioning. And to study how the enzyme functions, we have to actually look at the enzyme as it is down to that substrate. So in this particular case, so this is our starting point, and that's exactly where we get equation number one. So equation number one basically gives us the rank law of this reaction here, as the enzyme actually has the substrate at the active side and it transforms it into the product.