And this is known as a frame shift mutation. So insertion deletions can form frame shift mutations in which the entire reading frame, the entire mRNA sequence, is shifted. And that means that completely new codons will be read by our ribosomes, and a completely new sequence of amino acids will be produced. And this usually leads to non functional proteins. Now, let's take a look at the other type of insertion deletion, known as a non frame shift mutations. So, on the other hand, an insertion or deletion of nucleotides that is a multiple of three will simply insert or remove a number of amino acids equaling to the number of new codons that are added or removed.