We have this active side, we have the substrate shown in blue, and we have this inhibitor shown with our purple color. So this here is the allosteric side to which our inhibitor will bind, and this is the active side. So what this means here is the inhibitor can bind to the allosteric site regardless of whether this blue molecule, the substrate, is actually found inside that active site. So once the inhibitor binds to our enzyme, it will slightly deform our enzyme, it will change the enzyme threedimensional structure and that will also slightly change the structure of our active side. And even though the active side can still bind our substrate, the binding is no longer optimal and the enzyme activity will decrease. So once the inhibitor binds to our allosteric side, that conforms or change our enzyme, changes the shape of the enzyme, change the shape of our active side.