Now, what the tissue factor pathway? What the tissue factor pathway inhibitor does is it binds unto the tissue factor, factor seven complex, and it inhibits its activity. And it also has domains on this polypeptide that can bind onto the individual factor seven, and that factor ten, and it can inhibit both of these different molecules. Now, what about our intrinsic pathway? So let's take a look at protein C. Protein C is a vitamin K dependent protease. And what that means is it depends on the presence of vitamin K to actually effective correctly, to actually function correctly and effectively.