But abys phosphate will go on and bind onto pyruvate kinase and activate that molecule and that will increase the rate at which we actually produce those ATP molecules that are needed by our cells. So if we look at this process we see that increase in the concentration of ATP or alanine can cause a negative feedback loop and inhibits activity of periodicinase. But if we have low amounts of ATP that means we'll have high amounts of fructose one six bisphosphate which creates a positive feedback loop and stimulates the Peruvian kinase to carry out its process. So now let's summarize our results and let's begin by assuming that we're not exercising so our skeletal muscle tissue is at rest and what that means is we'll have plenty of ATP molecules to go around and so the energy charge of the cell will be high, the ratio of ATP to amp will be high. So if that is high, then that means ATP, the excess ATP will go on and bind onto that phosphorokinase. And what that will do is it will inhibit the activity of that enzyme.