So we see that in the next step, the phosphorylated CO2 can now attach onto the biotin of the enzyme and form that carboxy biotin enzyme intermediate. So this intermediate here and so this bond that is formed between the carbon dioxide and the biotin that is bound onto the enzyme is actually a very reactive bond. It's a very high in energy bond. And when we break that bond, that actually releases a certain amount of energy, that releases 20 kilojoules of energy. And so that's exactly why we call this an activated bond. Because it's an activated bond, it's very reactive.