And so what that means is, whatever this equation is, we have to be able to describe V Naught in terms of the concentration as of the substrate. And this equation has es. And what that means is we can actually use this equation and we have to somehow replace the Es concentration with the S. And that's exactly what we're going to do in all these steps, as we'll see in just a moment. So in the next step, we basically want to ask ourselves once we form this enzyme substrate complex. Well, first of all, how do we form this enzyme substrate complex in the first place? Well, to form this, we have to go in this direction.