But basically, by regulating this step, we call pyruvate carboxylation. By either turning it on or off, we can regulate the rate of the citric acid cycle. Now, that's the first process of regulation. The other two methods by which we can regulate the rate of the citric acid cycle is by regulating the steps of the citric acid cycle itself. So, out of the eight steps of the citric acid cycle, two of these steps are oxidative decarboxylation steps. And both of these steps are controlled by allosteric enzymes.