And so this enzyme's activity isn't high or the enzyme doesn't have any activity at all. And so the homogeneous aid cannot be transformed into four male acetoacetate, and this will ultimately not be transformed into these two molecules. And so because of that, we're going to see that homogenesate will accumulate in our cells, in our tissues, in our blood. Ultimately, the kidneys will be able to excrete this via the urine. And when the homogeneousate will be found in the urine and exposed to air, it will begin to polymerize. And that polymer product will basically cause a color change of the urine.