And cells like cardiac muscle cells, skeleton muscle cells and brain cells cannot actually undergo gluconeogenesis. These cells depend on liver cells and kidney cells ability to actually create these glucose molecules, dump these glucose molecules into the blood plasma, and then the blood plasma brings these glucose molecules to the cells, like the cardiac cells, muscle cells and brain cells of our body. Now, let's briefly discuss where we actually obtained these non sugar precursor molecules. So we know where pyruvate comes from. That comes from the breakdown of glucose. So when we don't have enough glucose in our body, we can actually take that pyruvate and essentially reverse the steps of glycolysis.