And one way by which we turn off this pathway is by inhibiting Pyruvate dehydrogenase complex from committing this molecule into the citric acid cycle. So we see that the kinase phosphorylates this, inactivates this enzyme and that prevents this reactor from actually taking place. Now, let's suppose we switch the argument. Let's suppose now our cells are contracting. And if the cells are contracting, we are using up ATP molecules and our energy charge value in the cell will drop. And if the energy charge value drops, we're going to have a relatively high concentration of molecules such as ADP.