And so what happens is the CO2 tramples into the red blood cell. Now, once inside the red blood cell, we have the same problem again because the cytoplasm of the red blood cell consists predominantly of water. So just like the blood plasma, the cytoplasm inside the red blood cell is also polar. And so the carbon dioxide cannot actually be stored inside the cytoplasm of the red blood cells in its CO2 form. And so what ultimately has to happen is the cell has to carry out this particular reaction in which we transform the non polar CO2 molecule into its polar form, bicarbonate ion. And because this contains a full negative charge, it can easily dissolve inside the cytoplasm of the red blood cell and also inside the blood plasma of our body.