And by binding they can create some type of change and that can actually alter the activity, the functionality of the enzyme. Now, allosteric enzymes and allosteric proteins basically observe something called Cooperativity. And we spoke about Cooperativity in detail when we discussed hemoglobin. So we basically said that an allosteric protein or an allosteric enzyme will observe Cooperativity. And what that means is the binding of a molecule onto a side on that enzyme or protein will affect the affinity of the other sides for that same molecule. And again, we focused on this when we discuss hemoglobin.