And more specifically, how exactly does change, changing the PH inside our cells effect the many different types of biological processes and reactions that take place within those cells? Now, what we're going to focus on in this lecture is how increasing the PH inside our nucleus of the cell actually changes the structure of the DNA, how it affects the double helix structure of the DNA, the formation of the double helix. So let's begin by looking at the following diagram that basically describes the relationship between the PH change and the structure of our DNA. So the x axis is the intracellular PH, the PH inside the cell. And as we go from left to right, the PH increases. Now, the y axis describes the percentage of the DNA molecules that exist in their double helix form.