Well, as you might know, the positively charged proteins will be attracted to the negatively charged beats beads. And the more positive charge we have, we know by Coulomb's law, the greater that attraction will be. And so what that means is these very positive, these proteins that have a very large net positive charge will be attracted to those beads. The ones that are slightly positive will be attractive, but not as much. The attraction will be less. And these negatively charged will not be attractive, they will be repelled.