And once we form the Pip three, the Pip Three basically moves along the membrane and eventually ends up on a protein known as Pip Three. So pip three dependent protein kinase. And once it binds onto this protein kinase, this protein kinase, shown in green, is able to activate an important effect of molecule important protein kinase known as protein kinase B, also known as AKT. So we see that phosphor, nototide three kinase, phosphorylates the Pip Two into Pip three that then travels along the membrane to activate a protein kinase we call Pip Three dependent protein kinase or simply PDK One. So this is PDK One and once PDK is activated by the binding of the Pip Three to this kinase, it then goes on and activates this structure here, which is the inactive form of protein kinaseb also known as AKT. So AKT One is activated and once this is activated, it can basically diffuse across the cell membrane.