So what we mean by that is this native active biologically active form of the enzyme contains these pairings, these disulfide bonds. So, for example, the first one is between the 26th and the 84th amino acid. But here the first bond is formed between the 26th and the. So that means this will contain the improper linkages between our 15 molecules and that will create an inactive molecule. Now, the question is, why did that actually take place? Well, the answer is simple.