And so two ATP molecules go into these two locations and once the ATP molecules move into that location that creates conformational changes in the entire structure of the transmembrane domain. And what happens is that induces this opening on the other side, the posing side of the membrane where that molecule actually came in. So it came in, let's say from the inside. So let's say this is the inside of the cell, this is the outside and now it opens from the outside and once it opens that molecule the substrate molecule can leave that cell and exit that cell. So we see the ultimate result of this particular mechanism is the same exact result that we saw in the ptype Atpas. That is, we move these molecules across the membrane against their electrochemical gradient.