That all creates a ripe work shift in the hemoglobin dissociation curve. Now, the final factor I'd like to discuss is carbon monoxide. Now, carbon monoxide is actually produced naturally inside our body, but it is produced in very, very small amounts. So the CO2, because it's produced in very small amounts in our body, does not actually affect the hemoglobin in any adverse way. But we produce carbon monoxide in much greater concentrations via different types of processes that take place outside our body. For example, cars produce CO2, and smoking also produces CO2.