Well, before we examine that, let's mention the following important points. So this is the first stage where we have amplification taking place. And so this is the first level of amplification. But how is amplification actually achieved in this stage? Well, a single epinephrine molecule, when it binds to this single structure, it not only induces the change of this g protein, it also induces the change of many other g proteins found in close proximity. And so not only this will this alpha domain, lose the GDP and bind the GTP.