So this is the equation that describes a general enzyme catalyze reaction at its beginning stages. So at the beginning, this is the chemical equation that describes any enzyme catalyzed reaction. So we have an enzyme and we have a substrate. And when they combine, when the substrate combines into the active side of the enzyme, we form the enzyme substrate complex Es and K. One is the rate constant of this reaction. Now, once we form this complex, there are two ways that this complex can basically dissociate the substrate. If it is not bound very strongly to that active side, it can simply dissociate and leave the active side without actually being transformed into the product.