And polar water molecules do not mix very well with nonpolar CO2 molecules. So only about 5% of the carbon dioxide, a very small portion, will remain dissolved in the blood plasma. And the remaining 95% of the carbon dioxide will move across the cell membrane of the red blood cell and into the environment found inside the red blood cell into the cytoplasm of the red blood cell. Now, what happens once the CO2 is actually inside the red blood cell? Well, some of that CO2 will go on and bind directly onto special groups on hemoglobin. And this is what we discussed in the previous lecture.