And once it moves into the pocket, as shown here, it basically creates overall conformational change that inverts the entire structure of that particular membrane protein. And so now, instead of pointing this way, it inverts. And this inversion, by the way, is also known as an eversion. We basically, instead of opening to this side, we now are open to the other side. So this is the inside or this is the outside, this is the inside of the cell. And so in this state we see that now the membrane protein is open to the outside.