Now, we're going to discuss this in much more detail when we get into biochemistry, but at this point I simply want to mention the filing for an idea about this Maca Lis constant. So the Michael is constant. Km does not actually depend on the concentration. What it depends on is the type of enzyme that we are dealing with. So the MACA's constant basically gives us information about the affinity or the traction of the enzyme to our substrate. So a very low Km value for any given enzyme means that the enzyme has a very high affinity for the substrate.