And those smaller pieces dissolve into our blood plasma and they travel to the liver and the liver cells basically hydrolyze and break down these even further. And then different components are basically recycled by our cell. Now, plasma, like most of these different enzymes involved in a coagulation cascade, initially exist in their inactive precursor zymogen form. And the zymogen of plasma is Plasminogen. So plasminogen is activated by another molecule known as tissue type plasmaigen activated so TPA. So essentially Plasminogen is a Zionogen, an inactive form of plasma that has a very high affinity for Fibon.