So we increase the temperature of the blood plasma within our capillary. So, now that we know where the increase in temperature actually comes from, let's discuss how our increase in temperature actually affects the ability of hemoglobin to bind to oxygen. So the question is, what would we expect to happen to hemoglobin's ability to bind to oxygen when we increase the temperature of the blood plasma that contains the red blood cells that are carrying those hemoglobin molecules? Well, when these exercising cells are carrying out more metabolic processes, that means they actually require more oxygen to create the ATP molecules via the process of cellular respiration. So that implies when these exercising muscles produce more ATP, they use more ATP. So that means they need more oxygen.