So an increase in the CO2 concentration, in the partial pressure concentration of CO2 inside this area, the red blood cells basically shifts the curve once again to the right side. So we see that increasing the hydrogen ion concentration, increasing the temperature, and increasing the partial pressure of carbon dioxide. The concentration of carbon dioxide will shift the entire curve to the right side. And what that means is more of that oxygen will be delivered to the tissues of our body. Now, what about something called two three BPG? So two, three BPG is two three biphosphoglycerate.