So, a nonsense mutation is a mutation when we basically change a codon that codes for an amino acid into a codon that is a stop codon, that terminates our polypeptide chain, and this basically terminates the polypeptide chain prematurely. And this causes or creates a non functional protein. So, basically, this concludes our discussion on genetic mutations. We have two different types of categories. We have insertion deletions and point mutations. Now, insertion deletions can cause frame shift or non frameshift mutations, but point mutations themselves are always is non frameshift mutations.