Now, what about the phosphorosotide cascade? What types of kinases are used in this case? Well, in our discussion we focused on two different types of kinases. We discussed protein kinasea and Cammodulen, so calm dependent protein kinases. And we said in this particular cascade and we used the physiological effect of decreasing or increasing blood pressure. We said that these two types of kinases are basically crucial for allowing that smooth muscle in the cardiovascular system to actually contract.