Now, what happens once the CO2 is actually inside the red blood cell? Well, some of that CO2 will go on and bind directly onto special groups on hemoglobin. And this is what we discussed in the previous lecture. This is what we call the Bore effect. So part of the part of the Bore effect tells us that CO2 molecules will bind onto special regions on the hemoglobin molecules and that will essentially form salt bridges and that will stabilize the T state structure of the deoxy hemoglobin and that will essentially decrease its affinity for oxygen. So how many or how much, what percentage of the CO2 molecules will bind to hemoglobin?