And this is important because, as we know, shock is a very dangerous medical condition and we don't want that individual to go into shock. And so this has to be an extremely effective and efficient process. And that's why we have many of these amplification positive feedback mechanisms. With factor ten. It activates factor eight to combine with factor nine, as well as this VWF, which stands for Von Willebrand Factor, which is another protein that is needed to basically stabilize factor eight. It activates the complex that goes on to activate more of ten to form this complex.