Now Allosteric Control is not the only method by which we can actually regulate the activity of our enzymes. Two other methods exist and these methods include proteolytic Activation or Proteolytic Cleavage, as well as reversible covalent modification. And these are the two methods that we're going to focus on in this lecture. So let's begin by defining and discussing Proteolytic Activation. Now a good quantity of the enzymes that are synthesized in living organisms, and this includes human beings, are synthesized in their inactive form and such inactive enzymes are known as zymogens or proenzymes. Now, under the proper environmental conditions, our zymogens, the inactive enzymes can be transformed permanently and irreversibly into their active form by a process known as proteolytic cleavage.