Also in activating its ability to actually catalyze this pyruvate decreboxylation step. Now, in addition to these regulatory pathways in eukaryotic cells, such as the cells of our body, we also have another important regulatory method. We actually use a type of covalent modification, namely for sporulation, to actually regulate the activity of this complex. So in eukaryotic cells, Pyruvate dehydrogenase complex is controlled via phosphorylation, a form of covalent modification. So let's study this diagram for just a moment. So this is our Pyruvate dehydrogenase complex in its active form.