So we have two types of setups, and in each setup, we have a funnel that is placed on top of a long column, and inside that column, we have special gel beads. Now, in this particular case, the gel beads are made so that they have a positive charge. And in this case, the gel beads are made so that they have a negative charge. For example, the gel bead can be made from a sugar polymer cellulose, and we can add special side groups onto the cellulose that make them negatively charged, as shown in the following diagram. So this is a single bead that is found inside this column here. So the setup in inexchange chromatography consists of a funnel placed on top of a narrow column.