And remember, lipid kinases are protein kinase that take a phosphoryl group from ATP and they move it onto some type of fat molecule, some type of lipid molecule. And to be more specific, the lipid kinase that this actually attaches to is known as phosphonosatide three kinase. So we have the phosphorylation of these four residues on this iris molecule causes this molecule here, phosphorositi Three kinase to actually attach. So the phosphorusati three kinase contains a regulatory region, shown here, that attaches onto the phosphorylated residue of the IRS molecule. And once this attachment takes place, that causes the active side of this lipid kinase to move in in close proximity with respect to the membrane. So this is the active side of this phosphor nosetide kinase.