So this enzyme catalyzes the deadenylation reaction, basically the breaking of this particular bond in this molecule. And so by the same argument, if we are able to build a molecule, a transition state analog that resembles the structure of the transition state in this reaction, in this deadenylation reaction, then we can build a very, very potent inhibitor to this enzyme. In fact, we can build this molecule that will act as a transition state analog. And notice there is a great deal of similarity between this molecule and this transition state. Now, the final question that I want to discuss is what exactly is the usefulness of this transition state analog? So one usefulness is the ability to build a molecule that is a very good inhibitor to some particular type of enzyme.