So the increase in concentration of this increases the concentration of the glucose six phosphate. And when that takes place, the rise in the concentration of glucosex phosphate causes a negative feedback loop with the hexokinase. And so it goes on and binds up to hexokinase and that causes hexokinase to basically inhibit its activity. And so we see that via the increase in the concentrations of these two molecules, the phosphorptokinase communicates to the hexokinase to basically stop carrying out its function, to basically stop the process of glycolysis. So they work together to basically stop producing ATP molecules when we have plenty of ATP molecules in our cells. So once again, hexokinase catalyzes the conversion of glucose into glucose six phosphate.