And it's prothrombinase, which is also a protease enzyme that activates prothrombin in our blood and turns it into the active With factor ten. It activates factor eight to combine with factor nine, as well as this VWF, which stands for Von Willebrand Factor, which is another protein that is needed to basically stabilize factor eight. It activates the complex that goes on to activate more of ten to form this complex. And Thorambin also activates via positive feedback mechanism, more of eleven and eleven is needed to activate nine. So we see that we have a really extensive network of positive feedback mechanisms that ultimately greatly amplify. They magnify the number of blood clots that can be formed in this process.