And when the cell is stimulated by some type of hormone or some type of action potential, these granules basically exit the cell via exocytosis and they release all these zymogens into the duct. And then the duct basically empties out into a larger duct which eventually empties out into the pancreatic duct. And it's the pancreatic duct that connects directly to the initial portion of the small intestine we call the duodenum. And once these zymogens are inside the intestine, they only begin to cleave those proteins when the Xiaomogens are activated into their fully functional form. So the question is, how exactly is Chimotryptynogen actually activated proteolytically? Well, as it turns out, interestingly enough, it's actually another active digestive enzyme known as trypsin, another protease that is responsible for activating Chimotrypcinogen into its active form, Chimotrypsin.