And then those red blood cells convert the majority of that CO2 into H plus ions and bicarbonate ions. But actually, a small percentage of that carbon dioxide, when it actually enters the red blood cells, goes on directly to the hemoglobin and binds directly to the hemoglobin at specific regions. And once CO2 binds onto the hemoglobin, what it does is it decreases hemoglobin's ability to bind to oxygen. And once again, less oxygen will be bound to our hemoglobin. And more oxygen will be ultimately released to the red blood cells, to the tissues, to the cells inside our exercising tissues. And this effect is known as the whole Dane effect.