So the one thing we have to know about this cycle is our TRH, the thyroid releasing hormone basically affects the entire pituitary in a positive manner. So this is a positive feedback cycle and this is also a positive feedback cycle. That basically means this build up in concentration causes this to build up in concentration and that causes our thyroid to basically increase the concentration of T three and T four. But T three and T four, as this builds up in its concentration it creates a negative feedback loop in terms of the interior pituitary and the hypothalamus. So the build up in this causes our interior pituitary and the hypothalamus to stop producing our TRH and the TSH. Now, the next hormone that is produced by the interior pituitary gland is our prolactin.