So once again, many different types of proteins inside the body can be modified by the addition of carboxyl groups. And one particular example is a protein and enzyme in the blood clotting cascade we call prothrombin. So prothrombin is needed to basically stop bleeding. And if prothrombin can't stop bleeding, then what that means is we're going to get a condition known as hemorrhage. Now, what happens is in some cases if, for example, our glutamate amino acid in prothrombin cannot be modified by this process of carboxylation, the addition of this carboxyl group, then our prothrombin will essentially not be as active, it will not be able to carry out its function correctly. And that can lead to the condition we call hemorrhage.