And this decreases the ability of water to actually hold on to one of those H plus ions. And this is precisely what facilitates this process the dissociation of the H from this oxygen to basically form this molecule here. And this is because the PTA value is lowered from 15.7 to 7.0. So this is very likely to actually take place. Now, once this takes place, now there's room for the carbon dioxide to basically enter the active side, the pocket of that enzyme. So this transforms a weak nuclear file into a very powerful nuclear file.