So our proteins can move around the cell. But when we have tie junctions, these integral proteins cannot actually go to this side of our cell membrane. And that's very important in basically controlling endositotic and exocytotic processes. So our tigunctions blocks the lateral movement of integral proteins from the apical side of the cell membrane. To the basil lateral side of that cell membrane. This means, or this makes sure that the proper endocytotic and exoptototic processes actually take place on the correct side.