So in the next step, we basically want to ask ourselves once we form this enzyme substrate complex. Well, first of all, how do we form this enzyme substrate complex in the first place? Well, to form this, we have to go in this direction. And what's the rate law for the formation of this enzyme substrate complex? Well, that is given by equation two. So the rate of formation of this enzyme substrate complex is equal to the product of the rate constant K one, and the concentrations of these two reactants, so E and S. Now, once we form the es.