And this is known as an embolism. So an embolism is the process by which these blood clots aggregate abnormally and they block that flow of blood to some area, some tissue or some organ of our body. And that can lead to many problems. For instance, if we have an embolism that takes place in the coronary artery that can lead to a heart attack and obviously, a heart attack is very, very dangerous. So there is a very, very fine line between thrombosis and hemorrhage. And to prevent either one of these from taking place and damaging our organs and tissues our body must be able to very precisely and very effectively regulate the coagulation cascade.