So once we form Thrombone, it calls upon platelets, it also activates another fiber protein known as Fibrinogen. And fibrinogen basically is activated into fibrin. So Fibrin is the active form of Fibrinogen, which is activated by Thrombin. And it's Fibrin that actually binds together to form that mesh like network within a rupture and that seals off that rupture. So basically the Fibrin, with the help of this protein, factor 13, which is also activated by Thrombin, the Fibrin can form these covalent bonds between other adjacent fibrin proteins. And so we eventually form these blood clots.