And so that's why they have a high concentration of the glute three, because this has a Km value around one. That makes it very, very effective in binding that glucose and bringing that glucose into the cytoplasm of the nerve cells. Now let's move on to glute three, glute four and glute five. And let's imagine that we just ingested a meal that is high in carbohydrates. And what that basically means is the blood level of glucose will essentially rise. And what will begin to happen is the beta cells of our pancreas of the eyelids of Langerhons will begin to produce insulin.