So, due to the higher affinity of carboxy hemoglobin to oxygen, it will make it much less likely that the hemoglobin will actually release the oxygen to the tissues and cells that are exercising in our body. Therefore, even though we'll have plenty of oxygen present in the atmosphere and inside our blood plasma, because carboxy hemoglobin binds oxygen so much more strongly than in the normal case, much less of the oxygen will actually arrive at the tissues of our body. And this condition that can ultimately lead to suffocation is known as carbon monoxide poisoning. Now, the other effect that the binding of carbon monoxide has on hemoglobin curve is the following. Notice that the blue curve is found much higher than the red curve. We see that there is a drop in our curve.