So these are basically seen as pathogenic antigens by our body. So these tiny antigens can diffuse across the epithelial cells and into the nearby tissue, where we have different types of wide blood cells. So bealympicides produce plasma cells and these plasma cells can recognize these antigens and begin to produce the corresponding antibody that binds to this antigen. And the most common type, the predominant antibody involved in allergic reactions, is immunoglobulin E. So immunoglobulin E is produced by the plasma cells. Now, what these immunoglobulin E antibodies do is they move on to the cell membrane of special wide blood cells found in the nearby tissue known as mast cells. So these mast cells contain these receptors that can bind to the constant region of our antibody, as shown in the diagram.