And this stimulates the removal of a hydrogen ion from the methyl group by aspertain 375. So together, these residues act on this acetyl coenzyme A and allows the formation of that enol intermediate molecule that now contains that pi bond between these two carbons of the acetyl group. Now, let's move on to four and five. So now, before this ENL intermediate can actually act as a nucleophile, we have to convert this oxyloacetate into a good electrophile. Because remember, anytime we have a nucleophilic attack, we have an electrophile that is actually being attacked. Now, in this form here, the oxyloacetate is not a good enough electrophile.