First, we want to basically ask and answer the following question if the solutions in our body consisted of nothing but pure water, would that be a good system to actually help prevent these drastic changes in PH? So, for instance, let's suppose we're inside the nucleus of our cell. And inside the nucleus, we have nothing but the DNA molecules and pure water. So what would happen if we add H plus ions into the nucleus? What would happen if we have an acid based reaction that takes place inside that nucleus where we have nothing but pure water and the DNA molecules? Well, basically, this curve describes this situation.