So the conversion of Pyruvate into the oxalo acetate intermediate by Pyruvate carboxylase. So these three steps essentially take place in the matrix of the mitochondria. Now, step two actually takes place in the cytoplasm. So, as we might imagine, now we have to basically transport that oxalo acetate intermediate into the cytoplasm. But before we actually transport the oxalo acetate, we have to reduce it into a malate molecule. And so what happens in the matrix of the mitochondria is an enzyme called malade dehydrogenase uses an NADH to reduce the oxalo acetate into malate.