So once inside the bloodstream, the steroid hormones need carrier proteins. Now, once these steroid hormones actually arrive at a target cell, they can easily transport themselves. They can easily move across the cell membrane, and that's because these are lipid soluble. Now, once inside a cytosol of our cell, these steroid hormones will basically bind onto receptor proteins found in a cytosol. And then the receptor protein hormone complex can then travel into the nucleus of our cell. And once inside the nucleus, the steroid hormone can basically create or induce some type of transcriptional change.