Now, in the parasympathetic case we always have a pre ganglionic and opposed ganglionic neuron. In the case of the sympathetic we usually have a pre and opposed ganglionic. But in the case of the signal being transferred into our adrenal medulla we only have a single neuron. In the pathway we have the pre ganglionic neuron. And once again, our sympathetic nervous system is responsible for monitoring and regulating the activities related with the fight or flight responses. But in the parasympathetic case we basically regulate the rest and digest activities.