And let's suppose when we're at the resting membrane potential. So a voltage difference of about negative 60 millivolts. This channel is closed. Now, as a result of the action of these ligand gated ion channels, there might be a change in the membrane voltage as we'll discuss in a future election. So this might become less positive or less negative. Let's say it decreases or it increases to about negative 40 millivolts.