And once again, that salvation shell, that cage of water molecules, is basically reformed. Now, this discussion basically leads to the next important point. If a molecule is polar or it has some type of charge, what that means is it will not be very likely to actually pass across the cell membrane. Why? Well, let's suppose this molecule has a charge. If this molecule here, shown in purple, actually has a charge, then that means these electrostatic interactions, which will be hydrogen bonds, will be very, very stabilizing.