So helper T cells assist with B and T cell differentiation and these also release their own cytokines and interlocutines different chemicals that essentially call upon cells like macrophages to that specific area. Now, cytotoxic T cells are like natural T cells because these basically attack infected cells, cells that have been infected by a viral agent or they can also attack cancer cells. But there is an important difference. Cytotoxic T cells are specific and what that means is they will only bind to a specific antigen while natural killer cells are nonspecific. It doesn't matter what type of antigen is found on the, on that pathogenic cell, this will bind to it. But this only binds to a specific cell.