And once we form these phosphorylated residues, we have an important adaptor protein known as GRB Two that binds onto this section and that calls upon another protein known as SOS. And what SOS does is it binds an inactive small G protein known as Ras. When Ras binds unto this structure, there's a conformational change that takes place in the Ras protein and the GDP Guanosine diphosphate is expelled and the GTP Guanosine triphosphate moves into that pocket. And once GTP binds, that activates that G protein we call Ras. And once Ras is activated, it moves on and activates a protein kinase we call Raff. And once this protein kinase is activated, it goes on to form these to activate other protein kinases we call mex the Max.