Because they are acid labeled they cannot survive under acidic conditions but a few of them actually make their way into the small intestine and that's where they begin to thrive, they begin to grow and they begin to infect the intestinal epithelial cells of that small intestine. So let's take a small section of the small intestine. Let's zoom in on this section. And this is basically what we get. So we have the lumen of the small intestine and this is our Vibrio cholera. Now this is the membrane of the intestinal epithelial cell.