Now, we have three mechanisms of inductive signaling. We have one called diffusion, one called direct contact and the other one called gap junctions. So let's begin with diffusion. So in diffusion, what happens is one cell that is next to another cell begins to produce a special type of ligand molecule and that molecule diffuses across the cell membrane into the extracellular matrix and eventually this ligand moves on to a nearby cell. It attaches onto a special protein receptor found on the membrane and by attaching it creates some type of secondary mechanism response. And so let's say some type of part of that protein on the other side basically detaches and then creates a secondary metric system that eventually influences the transcription and the translational process of that cell.