And so previously, we discussed the activation of this process. Now we're going to discuss the inhibition. So how exactly do we down regulate and inhibit the different enzymes involved in the coagulation cascade process? So this is what we're going to focus on in this lecture and we're going to discuss several important key factors that inhibit the enzymes that are part of the coagulation cascade. So let's begin with the molecule known as tissue factor pathway inhibitor or simply TFPI. Now, this is a polypeptide.