Now, the main difference between phagocytosis and receptor mediated endocytosis is in phagocytosis, we have the bacterial cell that itself contains receptors that bind to a receptor proteins on the membrane. In this case, the actual molecule that is being ingested binds directly to the receptors of the cell membrane. Now, once the binding process takes place that binding basically signals for invagination of the cell membrane to take place. And not only that, it also signals for the formation of a special type of protein layer protein covering around the vesicle. And the protein inside the covering is called clathrin. So that's exactly why this vesicle, once it's actually formed is called our clathrincoated vesicle.