Now, this Ras is actually attached into the membrane and that's because the Rasp protein contains a covalently modified amino acid that contains a lipid attachment and that lipid attachment remains inside the membrane. Now, once the Ras is in its inactive form, it goes on to activate another membrane, membrane bound protein known as RAF. And just like this structure contains the covalently modified lipid, this structure also contains a covalently modified lipid component that is found within the membrane. So both of these are essentially attached into the membrane. So in five or here we see activator Ras moves on to activate a protein kinase called a Ras. So this is a protein kinase and once this is activated, it goes on and activates other molecules via the process of asphylation.