So let's suppose we have a high blood glucose level, and this happens after we ingest some type of carbohydrate rich meal. So when blood glucose levels are high, what happens is glucose will act as an allosteric inhibitor. It will bind onto special regulatory sites, allosteric sites. And once they bind, they will create a conformational change in the structure of this phosphoralase A of the liver. And it will basically shift the equilibrium toward the T state. In the T state, the enzyme is not active, it has low activity, and so it will not break down glycogen into glucose.