On the other hand, we have factor eight, which is also known as the antihemophilic factor. And this is responsible for binding onto factor nine, which activates factor X into its active form. So protein C is responsible for essentially inhibiting the intrinsic pathway, while tissue factor pathway inhibitor is responsible for inhibiting the extrinsic pathway. So now let's take a look at another important molecule that acts as an irreversible inhibitor to thrombin. And this is antithrombin three. So antithrombin three is a glycoprotein whose structure actually resembles the structure of an inhibitor we spoke about previously, alpha one antitrypsin.