And Bax also punctures the membrane of the mitochondria. So it creates holes inside the outer membrane. And what happens is, once the holes are created, cytochrome C detaches from the membrane of the inner mitochondria and move to the outside of that mitochondria into the cytoplasm. Now, once inside the cytoplasm, so these are the cytochrom C molecules. The cytochrome C attaches to another type of protein known as apaf One. And once they attach, they form a special structure known as apotheosome.