And once that substrate binds to the active side, that will activate our enzyme. So this basically means that if we increase the concentration of substrate high enough, eventually all the active sites will be replaced by that substrate. And that means the overall maximum velocity V max or the maximum rate of activity of the enzyme does not actually change when we're dealing with competitive inhibition. And because we have to increase the concentration of the substrate to reach that maximum velocity, the Km, the mechaless constant, has to basically increase. And this means that our affinity for that substrate by that enzyme decreases. Now, let's move on to our second type of reversible inhibition known as non competitive inhibition.