Now, from basic biology we know that a double helix consists of these two single strands of DNA that run in an antipowerall direction opposite with respect to one another. Now, on the outside of the DNA we have the phosphate groups and we have the carbon backbone as well as the deoxyribosugars. And on the inside of that DNA double helix, we have the basis that pair with each other. So the question is how do intermolecular bonds, how does the reaction solvent and how does thermodynamics basically influence this reaction, the formation of the double helix of DNA. So let's begin with the intermolecular interaction. So the question is how exactly do these intermolecular interactions drive the formation of the double helix?