And now we add a trace amount of beta mecapto ethanol. So what he found was because we had a tiny bit amount of this catalyst, this catalyst essentially catalyzed the breakage of these incorrectly paired disulfide bonds. And eventually because of thermodynamics, we formed this native enzyme. Now what that means is it's the conformation, it's the structure of that native enzyme that is the most stable thermodynamically. And it's because of this that we have the breaking of these bonds and eventually the formation of this native structure. So if we take the scrambled enzyme and we add a tiny amount of beter mercapto ethanol, the betama captive ethanol will basically break these incorrectly paradisulfide bonds.