Now fact number two is peptide bond formation. The biosynthesis of peptide bonds is a thermodynamically unfavorable process. And what that means is we always have to input energy. We have to take energy away from ATP to basically form the peptide bonds that hold these amino acids together inside protein molecules. And fact number three is the reason that inside our cells these proteins don't spontaneously break apart. And these peptides don't spontaneously break apart is because this reaction here is kinetically unfavorable and this reaction is kinetically favorable.