And as removes as it is removed, we basically form this e two stage. And in the last step of this process, what happens is as soon as that phosphorus is removed, this interconverts back into the e one stage. And so now, instead of being open this side, it is open to this side. When that takes place, this entire section basically opens up. And now these calcium ions can once again go into the transmembrane domain and the cycle can basically restart itself. So we see that what the ptype Atpas does, what the calcium Atpas does is it moves two of these calcium ions against the electrochemical gradient from a low to a high concentration.