And remember, transition states are these structures that are so high in energy that they exist only for a very short period of time. So in that energy diagram, the transition state is the topmost portion of that energy diagram. Now, previously we discussed different types of enzyme inhibitors and we said that a very good enzyme inhibitor is an inhibitor that resembles the structure of that substrate. So if the inhibitor of some particular enzyme resembles the structure of the substrate that binds into the active side of the enzyme, then what that inhibitor can do is because it has a similar shape to the substrate, it can easily accommodate itself into that structure of the active sites. So we previously saw that a good way to inhibit the activity and the functionality of enzymes is to create an inhibitor that resembles that natural substrate of that particular enzyme. Now because of the argument that we just mentioned earlier.