Now in eukaryotic cells, eukaryotic cells contain DNA that have multiple origin of replications. And that means we have DNA replication taking place in multiple positions on that double stranded DNA molecule. However, in prokaryotic cells, prokaryotic cells contain DNA that usually only contain a single origin of replication. And that implies that DNA replication only takes place at one location and at one position on that prokaryotic DNA molecule. Now what exactly takes place once the DNA helicase enzyme actually binds to the origin of replication? Well, let's take a look at the following diagram that describes what is taking place.