And because those lipids, those fats, are not broken down properly, they basically build up, they accumulate in the lysosomes of our brain cells. And that accumulation eventually leads to many different types of problems. For example, blindness as well as mental disabilities. So we see that these different types of Autosole and recessive diseases are very, very dangerous. And normally, Autosole and recessive diseases act very quickly. They usually act in the first few months or the first few years of our life, of that individual's life.