They also bind onto B lymphocytes and that induces the differentiation of these B cells into plasma cells that are needed to produce antibodies floating in our blood. And they also induce differentiation into memory B cells that store the antibodies in case we are ever reinfected with that same pathogen. Now, these helper T cells also release special chemicals called cytokines. And these cytokines not only induce wide blood cell differentiation but they also stimulate the cells of our innate immune system. These are our macrophages, neutrophils, basafils and other wide blood cells of our innate immune system. So we see that by destroying the population of our helper T cells what HIV actually does is it severely weakens not only our adaptive, our acquired immune system but also our innate immune system.