It's going to begin the catalyzation process. But as soon as it begins the catalyzation process, what happens is because of the reactive nature of the penicillin. So remember, from organic chemistry, whenever we have a structure, a ring that consists of four atoms, so four member ring that creates a lot of steric hindrance and that increases the energy of that ring, and it makes it very reactive. In fact, that's precisely why this carbon will be very reactive. And what will happen is when penicillin actually enters the active side of that glycopeptic glycopeptide transpeptidase, this Serene will react, the oxygen will react with the carbon, and that will break this bond and that will relieve some of that stereotyinderrance that existed as a result of this high reactivity of this fourmember ring. So the betalactam.