And this is also true in a final type of inhibition known as non competitive inhibition. So we saw that in competitive inhibition, that inhibitor binds onto the active side of that enzyme because of the resemblance in structure. We saw that in non competitive, the only time the inhibitor can bind onto that enzyme is when the substrate is actually bound onto the active side of that enzyme, because only then will we create that pocket of space, the allosteric side that the inhibitor can actually bind to. Now, we see that in non competitive inhibition, sometimes the enzymes will have that active side as well as that additional pocket, that additional allosteric space, regardless of whether or not that enzyme is actually bound onto that substrate inside the active side. So some enzymes have a permanent allosteric site that can buy inhibitors. And these inhibitors are known as non competitive inhibitors because they do not buy into the active side.