Another example is shown on this side of the board. So the enzyme methyl Thio adenosine nucleusidase is basically the enzyme that catalyzes the hydrolysis of the bond between this carbon on the sugar molecule and this nitrogen on the base. And this reaction is known as deadenylation. So this enzyme catalyzes the deadenylation reaction, basically the breaking of this particular bond in this molecule. And so by the same argument, if we are able to build a molecule, a transition state analog that resembles the structure of the transition state in this reaction, in this deadenylation reaction, then we can build a very, very potent inhibitor to this enzyme. In fact, we can build this molecule that will act as a transition state analog.