So once we reach this value, we have a very rapid opening of these sodium voltage gated on channels. So let's take a look at the following diagram. So, when the membrane is at a resting memory potential of negative 70 millivolts, this structure is basically in its closed form. And this is the voltage gated sodium ion channel. Now, what happens when we go from this voltage difference to this voltage difference? These paddle domains essentially orient themselves upward.