And so what happens is, if there is a blood clot inside the right atrium and then it moves into the right ventricle and into the pulmonary, into our lungs, the lungs essentially act to break down different types of tiny blood clots. But if that blood clot isn't able to go into the lungs and goes directly into the left ventricle and then into the left atrium, then into the left ventricle, into our order, what happens is that blood clot isn't actually broken down because it bypassed the lungs as a result of this defect inside the wall between the two atrium. And now this blood clot can basically go into, let's say, some type of important organ, let's say the brain, and it could cause something called a stroke. This can lead to many, many problems. So although most of the time the patent for Raymond or Valley isn't dangerous, in some situations it can be very dangerous. On the other hand, the patent ductus arteriosis is a much more serious condition.