And the ADP adenine diphosphate will actually go on and inhibit the activity of kinase. In addition, Pyruvate will also inhibit the activity of kinase. And the kinase found on the E two component will no longer phosphorylate that Pyruvate dehydrogenase complex. Now, just because we're no longer phosphorylating this molecule doesn't actually mean the molecule will spontaneously go back into this state. We actually have to activate the phosphatase. Now, what activates the phosphatase to reverse these effects of the kinase?