And so we see that via the increase in the concentrations of these two molecules, the phosphorptokinase communicates to the hexokinase to basically stop carrying out its function, to basically stop the process of glycolysis. So they work together to basically stop producing ATP molecules when we have plenty of ATP molecules in our cells. So once again, hexokinase catalyzes the conversion of glucose into glucose six phosphate. And as the ATP level rises in the cell, phosphor fructokinase is disabled and this causes the buildup of the fructose six phosphate. And because fructose six phosphate is an equilibrium with glucosex phosphate that causes a rise in the concentration of glucosex phosphate. And this rise in glucosex phosphate creates a negative feedback loop that essentially inhibits the activity of the hexokinase.