It can basically expose important hydrophobic regions of the protein, and that can allow that protein to interact with other proteins, and that can stimulate many different types of reactions in the cell. So, again, due to the positive charge, due to a positive charge of two, calcium odds can form strong interactions with the negatively charged side chain groups of proteins, as well as the oxygen atoms on the carbonyl groups of the protein backbone. As a result of this, when calcium bonds to proteins, it can cause conformational changes in the structure of the protein, that can link different domains in the protein. It can expose, as we've seen in the case of Camodulin, hydrophobic regions. And that can be beneficial to that protein. So this can stimulate the activity of target proteins, target enzymes, target pumps, and so forth.