It includes its own molecule known as apatosis inducing factor or AIF. So the final mechanism of apatosis involves using apatosis inducing factor AIF to actually initiate the process of apatosis. This process does not use cast spaces. So what exactly happens? Well, AIF basically is located inside the intermembrane space between the two membranes of the mitochondria. And if the cell is actually damaged in some way, what happens is this AIF molecule is released from the mitochondria, it travels into the cytoplasm and then it moves into the nucleus of that cell.