So this is the process by which we produce our red blood cells. And we also destroy those red blood cells and recycle those red blood cells so that we can reuse some of the components to form more red blood cells in our bone marrow. So, to summarize, red blood cells are formed in our bone marrow and they are recycled, they are broken down by macrophages and either the liver, the spleen, or our lymph nodes. About 90% of the red blood cells are engulfed by those macrophages. But about 10% of those red blood cells, as a result of some type of strain, some type of force or some type of pressure, for example, a collision with the wall of the capillary, that can cause about 10% of those red blood cells to actually lyse directly inside our blood plasma. And the remnants of that lysing process are picked up by the macrophage.