And we see that we have active sites found right over here, right next to this domain and here right next to this domain. And interestingly, what happens is these two molecules don't actually bind to the active side together. It's the oxalo acetate that binds into the active side of that enzyme. Why? Well, because initially in its open confirmation the enzyme the citrate synthase only contains an active pocket, an active side for the binding of oxalo acetate. It does not yet contain a pocket that can bind the seeds of coenzyme a.