So when there's a rise in ATP, when we have a high energy charge value in the cell, when we're not exercising, we have too many ATPs. And so the ATP acts as a signal to basically inhibit the activity of pyruvate kindness. It creates a negative feedback loop, an inhibition loop. Now, as I mentioned in the beginning, glycolysis is not only used to actually create ATP molecules, it's also used to produce building blocks such as amino acids. And so there's no surprise that alanine is also an inhibitor to pyruvate kinase because pyruvate is actually used to produce alanine and so if there is an increase in the amount of alanine that we have in our cells, if we have too much alanine, then we don't want to produce the pyruvate anymore. And so the alena will go on and inhibit the activity of pyruvate kinase.