And that means the glucose will fit snugly inside this region. So as it essentially closes in, it basically squeezes all the water molecules out of this region. And so once we form this structure, we have this induced fit, this perfect fit, and all the water molecules have been removed from the active side. So it creates a perfect environment for this reaction to actually take place. So on top of actually creating this close proximity, it also creates an environment in which we don't have any water molecules. Now, why is that important?