Now, one example is the human body. The human body has a core temperature of about 37 degrees Celsius. And this is because most of the proteins, the majority of the proteins are enzymes in the human body, function optimally at this temperature of 37 degrees Celsius. So increasing the temperature will increase the rate until we go up to this optimal temperature. And by increasing it further, we see that our activity of that enzyme, which is the Y axis, will jar, will drop sharply. Now, this is basically exactly why it's dangerous to have a fever.