And now that group that was transferred into the active site of the enzyme by A is transferred onto this reactant B and that transforms that reactant B into product D and that basically ultimately releases that product D from the active site of the enzyme. And now the enzyme, the original enzyme in its original form is released by that reaction. So the major difference between the sequential reaction and the double displacement reaction is for the reaction to actually take place in a sequential reaction, both have to be bound onto the active side. But in this case, only one has to be bound for that reaction to actually take place. And in fact, the two substrates bind and are catalyzed at different times inside the active side of the enzyme that follow these double displacement reactions. So to see what we mean, let's take a look at the following general case.