So this is how we basically inhibit or activate the activity of Pyruvate dehydrogenase complex. Now, the final thing that I'd like to focus on is how there are certain cells of our body which also respond to hormones. And these hormones essentially stimulate or in some cases don't stimulate the activity of Pyruvate dehydrogenase complex. So let's focus on epinephrine and insulin. So, epinephrine is basically released by our body when we're on this stressful situation. So for instance, when we're trying to run away from some type of scary animal, for instance a bear, and as we're running away, we want to produce lots of ATP molecules to allow the skeleton muscle to actually contract.