Now proteolytic cleavage is also a permanent and irreversible process and that basically means that it only occurs once in the life cycle of that enzyme. Now, what are some examples of our body using Proteolytic Activation? Well, the process of blood clotting is one example of a biological process that involves a series of proteolytic cleavages. And we're going to discuss blood clotting in much more detail when we get into biochemistry. Another example of enzymes that undergo proteolytic cleavage to basically activate themselves are digestive enzymes. So to look at an example, let's focus on a specific type of enzyme known as Chimotrypsin.