Now, what that means is as soon as that individual is born, normally what happens is as a result of that reversal and pressure, the foraminal valley essentially shuts close. And eventually, because the lungs are oxygenated and we produce a special type of protein known as bradycanin. Bradycanin uses that oxygen, goes into the ductus arteriosis and begins to constrict the ductus arteriosis, eventually closing that duct off. So normally within several minutes, the voramino valley is closed. And normally within several hours, the ductus arteriosis is also closed. Now, in some situations, in some conditions, however, the fetus can develop a condition known as either the patent ductus arteriosis or the patent for Raymond O'Valley.