And as the excel age, the likelihood that nondisjunction will take place in meiosis and form an employed excels increases. And so if the likelihood of nondisjunction increases, that means the likelihood of down syndrome is also higher. So although the currents of down syndrome in the general population is actually very low, it's about zero point 15%, it increases with the increase in the maternal age in the age of that mother for the reason that we just discussed. So recall that female individuals produce all their ex cells before birth. So as the female individual ages, the Xcels also age. And the greater the age of the X cells, the more likely that those X cells will actually undergo nondisjunction during meiosis.