Now, what this molecule does is scientists created so scientists created this irreversible inhibitor, a bisubstrate analog known as the poly molecule which stands for and phosphor, acetyl, l, aspartate. And the structure of this poly molecule resembles the intermediate molecule that is formed in the bisynthesis of the CTP molecule. And this is what polar actually looks like. So polar resembles an intermediate in the reaction pathway and is therefore a highly potent, a highly effective inhibitor. It binds onto the active side because it resembles the bisepttrat analog that is formed as an intermediate in this particular reaction. And so once it binds onto the active side, it binds irreversibly and it does not let go.