If we remember that our body contains about 25 trillion red blood cells circulating in our blood circulation system. Now, 90% of these red blood cells that are damaged are recycled in our spleen in our liver and in our lymph nodes by specialized white blood cells known as macrophages. And the remaining 10% of those red blood cells actually lice. They break open directly in the blood, in our blood circulation as a result of being damaged by some other type of factor. So, for example, when our red blood cells age and when they become very fragile, if they are squeezed through that very tight capillary, they can actually lyse. And by lysing, they release the components to the blood plasma of our cardiovascular system.