So one of these reasons is a result of an error that might take place in one of the many processes that take place in the body. For example, one process in which an error can basically lead to a g mutation is DNA replication. So, during DNA replication, our DNA polymerase can basically make a mistake and incorrectly base pair a certain nucleotide pair, and that will create our gene mutation. So, these types of natural g mutations that take place as a result of one of the many natural processes that exist in the cell is known as a spontaneous mutation. Now, on the other hand, a gene mutation can also take place as a result of one or more physical or chemical agents known as mutagens. So these are basically outside physical or chemical forces that can basically induce our g mutation.