Now, in the presence of the inhibitor, that inhibitor can either bind onto that individual enzyme forming that enzyme inhibitor complex, or it can bind onto the enzyme substrate complex to form that particular enzyme substrate inhibitor complex. And notice that if we form the enzyme inhibitor complex, that doesn't change the likelihood that the substrate is going to bind to that enzyme. And that is important in part three, as we'll see in just a moment. So let's begin with one. The VMAX is lowered and the VMAX is lowered for the same reason that the VMAX is lowered in this uncompetitive inhibition case. So we simply decrease the number of active size, number of enzymes that are functional.