And so that suppresses the immune system and prevents it from actually mounting a defensive attack against that transplanted tissue or organ. Now, the major problem with this immunosuppression process is it's actually very dangerous. So as soon as we suppress our immune system we decrease its ability to find any type of to fight any type of infection. And that includes a simple infection from the common flu or the common cold. So because our immune system is suppressed it not only is not capable of fighting that graft but it also can't actually fight off any type of infection. So people that are immunosuppressed can sometimes die from the common cold or the flu because their immune system is not capable of mounting any type of defense or response.