How do they affect things like the turnover number, the Macalus constant, and VMAX, the maximum velocity of that enzyme? So let's begin by focusing on competitive inhibition. So this is the equation that describes competitive inhibition. So in the absence of an inhibitor, that substrate is going to collide into and bind to the active site of the enzyme, forming the functional enzyme substrate complex. And then that complex will catalyze and transform the substrate into the product, which will then dissociate and be released from that active side. Now, in the absence of an inhibitor, the curve that describes the substrate concentration to the velocity is this black curve here.