And so the magnesium can either interact with the alpha and beta oxygens or with the alpha and gamma oxygens or as in this particular case, the beta and gamma oxygens. And each time the magnesium interacts with two different oxygens that creates its own unique conformation. And so different enzymes require a different interaction because different enzymes require a different shape. And in this particular case, for adenylate kinase the magnesium must interact with these two oxygen atoms to give it the proper orientation and shape to basically be able to bind into the active side of that and MP kinase. Now, not only will the magnesium interact with two oxygen atoms of the triphosphate of the substrate, but the magnesium will also be stabilized by four different water molecules and that will give a stabilizing octahedral arrangement. So these are the two oxygens that come from the triphosphate group and these are the four oxygens.