And that's precisely why the curve is found towards the left side with respect to the blue curve because as we shift the curve towards the left side, that increases the affinity of that molecule hemoglobin towards oxygen. Now, in our red blood cells, we have this molecule, 23 BPG that can bind into that pocket because it's a small enough, and b contains the negative charges. And by interacting with the positive charges, we decrease the overall charge in that center area, and that stabilizes the t state of the deoxy hemoglobin and drives the equilibrium back towards the t state. And that decreases the affinity of the hemoglobin for oxygen. And that shifts the entire curve towards the right side. So from this black curve to this blue curve.