And so once the step takes place twice we form the same type of tetrahedral intermediate that we formed in the serene protease reaction mechanism. And just like in Seren proteases we can have an oxyanion hole that stabilizes the negative charge on that oxygen. Once we form the tetrahedral intermediate in cysteine proteases we can also have a similar type of oxygenine hole that stabilizes that relatively unstable and high energy tetrahedral intermediate. Now of course eventually the tetrahedral intermediate will collapse and after a few processes we're going to basically break that peptide bond in a similar way to how we broke the peptide bond in Serine proteases. Now two examples of cysteine proteases are cat spaces. These are those enzymes involved in the process of programmed cell deposit apatosis as well as cathypsons, which are involved in immunity.