That basically is the location where we unwind our double stranded DNA molecule. Now, a group of proteins known as initiation factors basically move along our double stranded DNA molecule until it reaches a special location a special region on the DNA known as the promoter region. Now, what the promoter region is it's basically a special sequence of DNA nucleotides that signals the RNA polymerase to actually join the protein complex and begin the synthesis of our RNA strand. Now the promoter region usually does not vary too much from one organism to another organism. In fact, the most common type of sequence that appears in our promoter region is known as the consensus sequence. And we'll talk much more about the consensus sequence and this promoter region when we'll get into the field of biochemistry.