That's what we mean by the membrane attack complex. So this is basically the classical pathway. And to initiate that classical pathway, part of the complement system, we need the antibody to actually bind onto that antigen to form the antibody antigen complex. So that we activate this C one and then the C one goes on to activate C two and C Four to form this complex. And this complex can either go on to activate C three or go on to activate C five which activates the membrane attack complex. So we have different types of mechanisms that are in play in the classical pathway.