But that's okay, because this will still hybridize. It will still anneale because all the other bases are paired up correctly. So as long as we use the exact temperature conditions needed for annealing to take place. Remember, annealing is the process by which two complementary sequences of nucleotides essentially hybridized. They bond, they form these hydrogen bonds. And so as long as we use the proper temperature conditions, this annealing process will still take place because all the other bases are paired up correctly.