So the dissociation of the enzyme substrate complex into the enzyme and the substrate. So the reaction going this way takes place much more quickly than the reaction going this way. So the dissociation going this way takes place much more readily than our dissociation into the enzyme and this product. So we suppose that the enzyme substrate complex dissociates into E and S much more rapidly and much more readily than E into P. And what this basically implies is the value of K two is much smaller than the value of K minus one. Because if this rate is much greater, that implies that K minus one must be much greater than K two. And if K minus one is assumed to be much larger than K two we can simplify this equation in the following way.