And this is the major method by which the cells of our body actually regulate pyruvate carboxylation and in turn regulate the citric acid cycle. Now, what types of conditions actually favor this state and what types of conditions actually favor this state? So let's suppose we're in a skeleton muscle cell and in that skeleton muscle cells we are at a resting condition. So what that means is we're not contracting those skeleton muscle cells and so they're not using ATCP molecules to actually generate those contractions of the actin mice and filaments. And under such conditions we're going to build up our ATP concentration. We're going to have a high energy charge value.