And going backwards, we also synthesize in the five to three fashion, which is the only way by which DNA polymerase actually synthesizes our new daughter DNA strands. Now, once we actually form all these Okasagi fragments, once we form the lagging strand, we have to connect those lagging strands. And the way we connect those strands is we remove these purple primers and we replace them with the proper nucleotides. And we connect the nucleotides by forming the phosphor disaster bonds. And the enzyme that basically does this is known as DNA ligase. So once the Okasagi fragments are formed, an enzyme called DNA ligase connects the Okasagi fragments by creating phosphodia ester linkages between our adjacent Okasagi fragments.