It's passed down from our presynaptic cell indirectly to the postsynaptic cell. Now, notice this electrical signal doesn't actually travel directly from the presynaptic cell to the post synaptic cell. Instead, we have this intermediate molecule, the neurotransmitter, that actually passes down that electrical signal. So this neurotransmitter in this type of pathway is known as the first messenger or the primary messenger molecule. Now, also notice that this neurotransmitter doesn't actually go inside the cell of the muscle cell. Instead, it stays on the outside.