And so what happens is the bicarbonate ions, about 85% of the initial carbon dioxide that entered this blood plasma exists in the form of the bicarbonate ions. So a special protein membrane in a cell, in the membrane in the red blood cell transports these bicarbonate ions into the blood plasma. Now, at the same time, this transport protein also pumps these chloride ions into the red blood cell. And the reason we have this exchange is because we have to ensure that there is no change in the electrostatic charge between the inside portion of the red blood cell and the outside portion of the red blood cell. And this exchange in ions, this effect is known as the chloride shift. So the chloride shift is simply the process by which this special protein membrane basically balances the charges by pumping this molecule to the outside and this chloride molecule to the inside.