This is the cytoplasm side and again this is the outside and these are all the different types of membranes that are membrane proteins that we might find in our membrane. So we have the seven TM receptor which is also known as the G protein coupled receptor and it basically contains G protein but because it's activated that G protein has moved on and bound to adenyly cycling. So if we think back to the epinephrine signaling pathway this is exactly what it looks like. So we have our seven transmembrane helix receptor that basically is bound to the G protein. But when that ligand, the primary messenger shown in orange actually binds onto the seven TM receptor that G protein, the G alpha protein to be more specific actually detaches and goes on and binds onto a dentalt cyclase. And then the cyclase basically transforms ATP into cyclic amp that goes on and binds and activates protein kinase A and protein kinase A goes on and affects different types of enzymes and protein effectors.