So we have, let's say, three of these misfolded proteins. Now, because they consist predominantly of these blue betapeted sheets, they are drawn in blue. Now, because of the presence of these beta pleated sheets, they will bond with each other as a result of those beta beta pleated sheets being attracted to one another via non covalent bonds. And so, eventually we form this multi unit and aggregate of three PrPSc molecules. Now, let's suppose we have these red molecules in close proximity that are normal. Now, somehow by mechanism that we are still unsure of these infected molecules, these misfolded proteins can somehow transform these normal proteins into these abnormal proteins.