For example, if, let's say, this is negative ten, but this is positive 20, that means this value will be a positive value. And whenever our delta S of the Universe is a positive value, that means at that particular temperature, the Delta G that gives free energy will be a negative value. And so our reaction will be spontaneous, it will be favorable, and the product molecule will be formed. And in this case, that double helix DNA molecule will, in fact, form. So this is basically what we have to do, what we have to think about every time we examine a reaction in biochemistry. We have to think about how these different types of factors will influence that reaction pathway and the final structure of that final molecule.