Now, what's so special about the enhancer? Well, basically, the enhancer can also bind special transcription factors. And when a transcription factor bind onto the enhancer, the enhancer will essentially loop around and bind onto the protein complex found on the promoter. And this interaction will stimulate transcription and increase the rate of transcription of this gene. So the enhancers are segments of DNA that are typically located far away from the gene. They can be either upstream, they can be either downstream, or they can also be, in some cases, inside that gene itself.