Now, these sickle shaped red blood cells can aggregate and clog the tiny capillaries found in our cardiovascular system and this can result in painful swelling, impaired blood flow, increased risk of stroke as a result of poor blood flow to the brain, as well as increased risk of pathogenic infection as a result of the impaired blood flow. Now, in addition to these different results, these abnormal shaped red blood cells, the sequel shaped red blood cells, have a shorter lifespan. And what that means is that will cause these red blood cells to die quicker. And so there will be a decrease in the number of red blood cells found inside our body. And this is known as anemia. And that's exactly why we call this condition sickle cell anemia.