So red blood cells are released into our blood. Now, after about 120 days of circling our cardiovascular system, they essentially are damaged to the point where they either lice directly in our blood or they go into our spleen, into our liver or end up in the lymph nodes. And the white blood cells engulf those damaged red blood cells and form this vacuole inside that combines with the lysosomes of the macrophage. And the lysosomes contain digestive proteolytic enzymes that can break down the red blood cells. Now, notice when hemolysis of the blood cell takes place inside our blood, the contents of our red blood cell is spilled into the blood plasma. Now, what are the contents of the red blood cell?