So the problem with this reaction is so if we study the rate of this reaction in its uncatalyzed form at a PH of seven, at body temperature of, let's say, 37 degrees Celsius, we'll see that the rate of the reaction isn't that great. In fact, the rate is nowhere close to what it should be to actually be able to meet the demands of all the trillions of metabolizing cells found inside our body. So to basically increase the rate to a high enough value so that it can keep up with the demands of our body, what the red blood cells have is they have this enzyme we call carbonic anhydrase, too. So inside our body, we have at least seven types of carbonic and hydraase enzymes. But the one that is found inside the red blood cells is known as carbonic and hydrase two. Now, what we want to discuss in this lecture is the active side of this carbonic and hydrate two.