And once that active side moves there, it causes the phosphorylation of a specific type of fat molecule that exists within the membrane known as Pip two. Now, when did we see Pip Two previously? Well, we actually spoke about Pip Two in our discussion on the phosphornosatide cascade. And we said that Pip two, Pip Two stands for phosphatididylin nosetal 45 diphosphate. So this molecule contains a polar region that points towards the cytoplasmic side and a non polar region that consists of two tails that lies within the membrane. Now, what this lipid kinase does is it basically attaches a phosphoryl group.