And specifically, it's the difference between the energy of the product and reactants that determines the concentrations of products and reactants that will exist at equilibrium. Because the enzymes do not affect the energy values of the products and reactants, they will not affect the concentration of the products and reactants that will exist at equilibrium. So once again, we know that enzymes do not affect the free energy of the reactants and products. This implies that they will not change the equilibrium of the reaction. That is the same concentration of products and reactants will be formed in the presence as in the absence of the enzyme. So this is the case where we have our uncatalyzed reaction.