So let's take a look at the following diagram. So let's say we drink we drink the contaminated water that contains vibrio cholera. It makes its way into our stomach where the majority of them actually die off. Because they are acid labeled they cannot survive under acidic conditions but a few of them actually make their way into the small intestine and that's where they begin to thrive, they begin to grow and they begin to infect the intestinal epithelial cells of that small intestine. So let's take a small section of the small intestine. Let's zoom in on this section.