So we have K one multiplied by these two concentrations is equal to K minus one multiplied by Es plus K two multiplied by Es. Notice on the right side we have these two same terms and we can bring that out of our equation to get the following result. And now we can basically bring all the concentrations to the left side and all the K values, the rate constants to the right side and we get this equation. So the product of the concentration of the enzyme in the substrate divided by the complex concentration is equal to K minus one plus K two divided by K one. And instead of using these three rate constants, we basically set this ratio equal to a new ratio defined by uppercase K with the M subscript. And this is known as the Michaelis constant.