So we see that the rotation of the gamma subunit that basically lies within the inner cavity of the hexamer ring basically allows the interconversion of the beta subunits from one state to another state. And notice that at any given moment in time all the beta subunits exist in a particular distinct state. And that applies that any given two subunits, two beta subunits will never exist in the same identical state. So we have three of these different subunits and they exist in different states. And that's a result of the orientation of this central gamma structure that exists in the central cavity of that Hexima ring. So once again and let's summarize the following diagram and this entire mechanism by which this takes place is known as the binding change mechanism.