Now of course eventually the tetrahedral intermediate will collapse and after a few processes we're going to basically break that peptide bond in a similar way to how we broke the peptide bond in Serine proteases. Now two examples of cysteine proteases are cat spaces. These are those enzymes involved in the process of programmed cell deposit apatosis as well as cathypsons, which are involved in immunity. Now let's move on to aspartate proteases, also known as aspertyl proteases. Now the major difference between cysteine proteases and aspirations is the following. In cystine proteases as well as the serum proteases we see that one of the residues inside the active side of the enzyme acts as a nuclear file.