Now, the fact that they're water soluble and not lipid soluble means that they cannot actually pass across the cell membrane of the target cell and they bind onto receptors on target cell membranes and they create a secondary messenger response to basically initiate some type of effect inside the target cell. So epinephrine and norepinephrine are very similar in the type of response that they create inside our cell and inside our body as a whole. So epinephrine is responsible for increasing the rate of our heart, the rate at which our heart pumps blood, and also the force with which our heart actually pumps that blood. So that means because of epinephrine, the blood can get to our tissue faster and more blood can get to those tissues. Now, what this also does is it increases the rate of respiration so that we breathe more and more oxygen basically gets to our tissues. Now, epinephrine also increases the breakdown of glycogen inside our liver cells into glucose so that we have more glucose in our blood readily available to be used by our cells of the body to create ATP for energy.