Another important pathway that uses these seven TM receptors is the phosphoride signal transduction pathway or simply the phosphorusotide cascade. Now, before we actually take a look at the details of this particular signal transduction pathway, what's an example of a g coupled protein receptor inside our body that uses this pathway? Well, one common example is angiotensin two receptors. So this is a g coupled protein receptor that actually uses this pathway to regulate the blood pressure inside the cardiovascular system of our body. So we have a primary messenger, a peptide hormone known as angiotensin that binds until angiotensin two receptor and that initiates this phosphonositide signaling pathway. So now let's actually move on to this pathway.