And so more oxygen is unloaded into the exercising cells of our tissue. So when our metabolic rate inside the tissue increases, they require more oxygen to actually produce ATP. And that's exactly why the two three DPG interests the red blood cells in the first place to stimulate our deoxy hemoglobin to not actually bind to the oxygen, so that more oxygen is allowed to travel into the cells of the exercising tissue. So, once again, from the graph, we see that 23 BPG helps unload more oxygen into the metabolically active tissue. At a partial pressure of about 40 mercury, the red curve shows a smaller percent saturation, about 60%, compared to the blue curve, which shows about 70%. And this implies that when 23 bifoxylglycerate is present, it is bound to deoxy hemoglobin, and it makes it much less likely to attach to oxygen.