Let's take a look at this summary. So we have the beta cells of our pancreas secrete insulin. Insulin binds onto the insulin receptor protein that initiates the insulin signal transduction pathway and that ultimately leads to the activation of protein kinases. These protein kinases then go on to deactivate glycogen synthase kinase into its inactive form. So it stimulates the inactivation of this molecule. Now, this molecule in the active state keeps the glycogen synthase A in the inactive state.