So let's take a look at what actually happens and let's look at the following flowchart to basically help us guide through the process of inflammation. So let's suppose the pathogen essentially invades our tissue via some type of cut inside our skin. So the skin fails at preventing and acting as a physical barrier. Now, once a pathogen actually enters the tissue of our body, what happens is nearby cells called mass cells, which are basically cells that are physically situated in our tissue around that area begin to secrete special types of chemicals known as cytokines as well as histamine. And these chemicals basically help dilate the blood vessels that lead to the infected area and we'll see why that's important in just a moment. So mast cells are situated within the tissue and release histamine and other chemicals called cytokines that promote inflammation.