So what other connective tissue do we have in our body? Well, bone, bone is a type of connective tissue and so the skeletal system is also formed from the mesoderm germ layer. And that makes sense because it is located in between these two layers. So we have the bone and the bone marrow, the red bone marrow and the yellow bone marrow are basically formed from our mesoderm layer as well as our cartilage. Now together the cardiac muscle which consists of these two types of muscle, the cardiovascular system which consists of these two types of muscle as well as the skeletal system, makes up the musculoskeletal system. And so the entire musculoskeletal system which begins with M, is formed from the mesoderm germ layer.