So remember this point because we're going to cover it again in a future lecture when we discuss how we actually regulate the process of gluconeogenesis. Now, by the way, this entire process, step one, takes place entirely in the matrix of the mitochondria of our cell. And that's because Pyruvate carboxylase is only found in the matrix of the mitochondria. So the conversion of Pyruvate into the oxalo acetate intermediate by Pyruvate carboxylase. So these three steps essentially take place in the matrix of the mitochondria. Now, step two actually takes place in the cytoplasm.