So we see that in this biological synthesis of CTP, it's the end product. It's the CTP itself that goes back to the beginning, to the first step in the reaction and inhibits the activity of this aspartate transcarbolase. And we know from basic biology that this type of pathway is known as the negative feedback loop or negative feedback inhibition. And this CTP molecule is known as an allosteric inhibitor of this enzyme. And that's how we know that this enzyme is controlled allosterically inside our cells. So once again, these results suggest that the end product of the atcase initiative reaction must bind onto and inhibit the activity of that aspartate transcarbomolase.