So once again, when fructose six phosphate concentration is high, some of it is transformed into fructose 206 bisphosphate. And this molecule is an allosteric activator of the enzyme. It binds to that enzyme, stimulates its activity and it continually carries out this process quickly and effectively. Now let's move on to hexokinase. So let's suppose inside our blood we have a high concentration of inside our cells we have a high concentration of ATP. So we're essentially at rest and the high amount of ATP will begin to inhibit the phosphorptokinase.