So when we have low mass of ATP, we want to produce ATP. And so these are the enzyme, these are the allosteric effect, they're shown in blue that activate the process of glycolysis under low energy conditions. So in this particular case, if we have lots of Amp, the same Amp that inactivates this actually activates the phosphor fructose kinase. On top of that, the st fructose 26 bisphosphate that inactivates this actually activates this. So this molecule is activated by these two Alastairs effectors and pyruvate kinase is activated by the build up of fructose six bisphosphate. Now, why does that actually make sense?