Now, suppose that individual of that fetus is born under hypoxic conditions and that means they do not have enough oxygen circulating inside their blood. In such a case, the bradyclinan cannot actually act effectively and efficiently because there is not enough oxygen. So it will not be able to seal off that ductus arteriosis. And that fetus develops a condition known as patent ductus arteriosis or PDA. That basically means that duct had not closed. Now, what will happen in such a case?