A few seconds to a few minutes following the activation of the alphae protein by the attachment of the GTP, the alphagy protein itself can actually take a water molecule from the cytoplasmic environment and use that water molecule to hydrolyze the GTP back into GDP. And as soon as that takes place, as soon as we replace the GTP in place a GDP, that will decrease the affinity of the alphagy protein for the cyclist, causing it to dissociate from that cyclist. And once it dissociates, it goes out and finds those beta and gamma units to basically reform this primer molecule. And once it detaches, that inactivates that adenylate cycling. So once again, as long as that GTP is bound to the alphagy protein, that alphagy protein will remain attached to that adenylate cyclist, which will in turn continue producing those cyclic adenosine monophosphate molecules. So if that G protein is to detach from that cyclase, the GTP must be transformed into GDP.