We have the intermembrane space and we have the mitochondrial space. Now, if our cell commits to cellular respiration in the presence of oxygen, these two pyruvates are transported via specialized proteins known as integral proteins. So we have integral proteins on the outer membrane and integral proteins on the inner membrane, shown in green. And these pyruvates are basically transported via these membranes into the mitochondrial matrix of this mitochondrion found inside that cell. Now, once our pyruvate molecules are inside the mitochondrial matrix, they will undergo a process known as oxidative decarboxylation, and this process is known as pyruvate decarboxylation. So basically, three enzymes joined together to form an enzyme complex known as pyruvate dehydrogenase complex.