So remember, when the fossil lipase binds or when the fossil lipase cleaves the Pip two, we not only form the IP three secondary messenger, we also form the dag secondary messenger. And now that calcium is bound to the protein kinasea, that allows the dag to go on and bind to protein kinase C. And once this takes place, it activates protein kinase C. And protein kinase is a specific type of kinase which means itphosphorylates target enzymes and protein. So protein kinase C, for instance, can initiate things like smooth muscle contraction, it can also initiate the breakdown of glycogen into glucose molecules and many, many different types of processes. So ultimately this structure as well as this structure go on to basically initiate many different types of cell processes that ultimately create that physiological effect. And in the instance, in the case of angiotensin two receptor, that final physiological effect is the increase or the decrease in the blood pressure in the cardiovascular system. So this is what the phosphorotide signaling pathway actually does.