And when this complex exists, as shown, that adenylate cyclists will basically continue transforming the ATP molecules into the cyclic Amp molecules, which are the secondary messengers in this Epinephrine pathway. So ultimately, what causes the alphagy protein to actually bind and stimulate that adenylate cyclist? Well, basically, it's the GTP. When the GTP Guanosine triphosphate is bound onto that AlphaG protein, it increases its affinity for that adenolid cyclist. And so it goes on and binds until special site found on the intracellular portion of this cyclist. And once it binds, it increases its catalytic activity and causes it to basically transform the ATP into the cyclic adenosine monophosphate molecules.