And in the matrix, the Pyruvate will be transformed via an irreversible step into acetyl coenzyme A. And what this step does is it commits the CETL coenzyme A, the derivative of Pyruvate, into one of two different pathways. We either commit the CETL coenzyme A to undergo the TCA cycle, the citric acid cycle, or also known as trichrobicylic acid cycle to generate those NADH molecules and fadh two molecules to basically form ATP via the electron transport chain. Or under other conditions, the CETO cola enzyme A can be committed to a second pathway that produces lipids. And we'll talk more about that in a future lecture. So we see that the Pyruvate decarboxylation process is a very important step, very crucial step in glucose metabolism because it essentially commits that glucose derivative molecule, the Pyruvate, into carrying out the citric acid cycle or in some cases, lipid synthesis.