Moment in time. Because if it can turn off that pathway, that will lead to many different types of negative effects, as we'll discuss in the future lecture. So what I'd like to focus on in this lecture is I'd like to answer the following question. So, once that Epinephrine signal transduction pathway actually carries out its ultimate goal of producing that specific type of physiological response due to some type of stimulus, how is it that the cells can actually shut down this pathway? What methods can they actually use to shut down this Epinephrine signal pathway? Well, basically, there are two points in the Epinephrine pathway that the cell can actually use and shut down that pathway.