And this complex can go on and stimulate the activity of different types of protein kinases. And remember, protein kinases phosphorylate and activate target enzymes and proteins. Now, the other thing that the calcium mines can do is they can go on and bind onto a specific type of kinase found on a membrane, on the intracellular side of the cell membrane known as protein kinase C. When the calcium binds onto protein kinase C, it basically creates a pocket that allows the dag. So remember, when the fossil lipase binds or when the fossil lipase cleaves the Pip two, we not only form the IP three secondary messenger, we also form the dag secondary messenger. And now that calcium is bound to the protein kinasea, that allows the dag to go on and bind to protein kinase C. And once this takes place, it activates protein kinase C. And protein kinase is a specific type of kinase which means itphosphorylates target enzymes and protein. So protein kinase C, for instance, can initiate things like smooth muscle contraction, it can also initiate the breakdown of glycogen into glucose molecules and many, many different types of processes.