And we said that Pip two, Pip Two stands for phosphatididylin nosetal 45 diphosphate. So this molecule contains a polar region that points towards the cytoplasmic side and a non polar region that consists of two tails that lies within the membrane. Now, what this lipid kinase does is it basically attaches a phosphoryl group. It takes a phosphoryl group from an ATP molecule and it places that phosphoryl group onto the Pip two and that creates Pip Three. So Pip Two stands for phosphatidolinotitol four, five, diphosphate, but Pip Three stands for phosphateidolinosatoll three, four, five triphosphate. And so we see that this phosphor noseattype three kinase phosphorylates the third carbon on this Pip Two to form the Pip three.