So we basically activate these osteoclasts, we recruit them and we signal exactly where we want our rebuilding process to take place. Remodeling process to take place. Let's suppose it's here. So these osteoclasts children in red are activated, they're recruited and eventually they bind. They attach onto the surface of this section, as shown in this diagram. And as soon as the osteoclast attach, they begin the process of resorbing.