So about 10% of the red blood cells lyse and this process is known as hemolysis directly in our blood circulation. Their remnants are eventually picked up by the macrophages, as we'll see in just a moment. Now, the majority of the aged or damaged red blood cells end up in our spleen, in our liver, or in our lymph nodes. And the white blood cells we call macrophages, which are phagocytic cells, essentially engulfed, digest and recycle the different components of red blood cells. So to summarize what we describe and to discuss how this process takes place, let's take a look at the following diagram. So, let's begin in region number one.