But just because we form the enzyme inhibitor complex, that doesn't mean that the substrate will not be able to bind into the active site. In fact, the substrate usually does bind into the active site. But the problem is, once we form the enzyme substrate inhibitor, as in this particular case, that prevents that enzyme from actually catalyzing the transformation of that green substrate into this purple product. And so here, no reaction takes place. Now, if the inhibitor departs, then we form this enzyme substrate complex, and only then can it go on to form that particular product. So unlike in competitive inhibition, and unlike in non competitive inhibition, in non competitive inhibition, what the binding of the inhibitor does is it lowers the turnover number of that enzyme, kcat.