And what factor eleven does is it goes to activate factor nine and that ultimately creates more of these dimers as shown in this diagram. Now, Thrombin also activates factor eight. And factor eight essentially circulates in our blood and it attaches to this VWF factor, which basically stands for a Von Villebrand factor. And the Von Villabrant factor is a protein that attaches to factor eight and stabilizes its structure, then attaches to factor nine. And this complex essentially goes on and activates the formation of prothrombinase. So Thrombone activates this complex, it activates factor eleven and it also directly activates factor five.