So what is this process that allows us to actually replenish the oxyloacetate concentration? Well, it's a process that we actually discussed when we discussed gluconeogenesis. So remember now discussion on gluconeogenesis. In gluconeogenesis, the first step in that process is to transform the Pyruvate molecule into oxyloacetate and the enzyme that catalyzes this step is Pyruvate carboxylase. So Pyruvate carboxylase essentially attaches a carbon dioxide molecule onto that Pyruvate to form oxyloacetate. In the process we essentially break down an ATP to drive this process in this direction.