Now, what about the acetoacetate and D three hydroxybutyrate? Well, these are actually acids, and the PKA value of these two acids is around four. And what that means is once these two molecules into the bloodstream, they're going to dissociate, releasing those H plus ions, and that will increase the acidity of the blood. So we see that these two Ketone bodies will increase the levels of H plus ions in the blood, and that will, in turn, increase the H plus ion concentration in the tissue. In addition, what will also happen is as a result of ketonuria, the release of these Ketone bodies in the kidneys, what will happen is osmosis will take place inside the kidneys. And so we're going to release much more water than usual.