And we're going to summarize what these factors are. So we're going to examine PH, temperature, carbon dioxide, two, three by phosphoglycerate, as well as carbon monoxide. We're also going to discuss how these different factors affect the oxygen hemoglobin dissociation curve. So let's begin with factor number one, the PH of our blood plasma. So let's take a look at the following diagram. So this is the cell found inside our tissue.