And this is basically what we get. So we have the lumen of the small intestine and this is our Vibrio cholera. Now this is the membrane of the intestinal epithelial cell. This is the cytoplasm side and again this is the outside and these are all the different types of membranes that are membrane proteins that we might find in our membrane. So we have the seven TM receptor which is also known as the G protein coupled receptor and it basically contains G protein but because it's activated that G protein has moved on and bound to adenyly cycling. So if we think back to the epinephrine signaling pathway this is exactly what it looks like.