They cause the transformation from the R state, the relaxed active state into the T state, the 10th state and the 10th state is the inactivated state. So upon the rise of glucose concentration it basically stimulates the transformation of our state into the T state. At the same time it decreases the traction between the protein phosphatase one and the phosphorase A. So upon the binding of glucose these two structures basically dissociate. So let's suppose one goes here, this is phosphorase A in a T state and the remaining portion goes here. And as soon as the dissociation takes place that activates this protein phosphatase one.