So let's now focus on what happens here. So the conformational changes here lead to conformational changes here. And so what happens here is this C terminal tail that we mentioned just a moment ago basically moves into the active side of that corresponding of that opposing unit. So this he tail basically moves into the active side of this one and this heat tail moves into the active side of this one. And once they move in, what that active side does is it phosphorylates the tyrosine residues and it phosphorylates up to five residues found on this Sea terminal tail. In this case I've only shown four.