So we see that the product of this particular reaction is an active ubiquitous molecule that contains this amp group. And so now it's a high energy molecule. We release the Pyrophosphate and now E One, this enzyme, the Ubiquitan activating enzyme, basically catalyze the transfer of this blue region onto the active side of E One. So we see that the active side contains a cysteine. And this is the S atom that is part of the side chain group of the cystine and it attaches onto the carbon of this ubiquitous molecule. And so we see that this amp is released in the process.