Now, ACTH is released from the anterior pituitary gland at times of stress and it basically carries that hormone via the bloodstream into another endocrine glands in the body known as our adrenal cortex. And ACTH causes our adrenal cortex to basically release a group of hormones known as glucocorticoids via a secondary messenger system. And we'll discuss these in more detail when we'll focus on the adrenal cortex. Now, the third type of hormone is our thyroid stimulating hormone or TSH. And the hormone that is released by the hypothalamus that stimulates the release of Tch is known as thyroid releasing hormone. So the hypothalamus releases the thyroid releasing hormone and it travels down the portal veins into this system and that stimulates the release of our thyroid stimulating hormone.