And that means they cannot actually cleave the majority of the ester bonds that basically hold the triglycerides, the lipids together. In other words, the pancreatic lipase can only cleave the bonds the lipids found on the surface of the fat globules and they have no way of actually getting inside those fat globules. Now this makes the efficiency and the rate at which lipase actually cleans the bonds very, very low. And what happens is in order to increase the rate and efficiency at which our lipase molecules actually break those ester bonds to form fatty acid and glycerol the liver produces a special type of fluid known as bile. So bile consists of amphipatic molecules such as phospholipids and bile salts and it also consists of hydrophobic molecules such as cholesterol. Now, antipatic simply means these molecules do not only have a hydrophobic section, they also have a hydrophilic section.