Now, another equally important effect is known as the halding effect. And the Held in effect is really the opposite, the reverse of the Bore effect. So remember, the Bore effect talks about how the concentration of CO2 and hydrogen affect hemoglobin's affinity for oxygen. But what the helldon effect does is it takes the opposite perspective. It talks about how the concentration of oxygen inside the red blood cell, inside our blood actually affects hemoglobin's affinity for carbon dioxide and H plus ions. Now, why is the Haldane effect actually important?