So what do you think would happen if there is some type of defect or deficiency in any one of the enzymes involved in the urea cycle? Well, since this is the only way by which we rid the body of ammonium, that implies a deficiency in any one of these enzymes will decrease the ability of our liver body to actually eliminate ammonium. And that will drive the levels of ammonium inside our body up. So that will cause a medical condition we call hyperammonemia, high levels of ammonia inside our blood. Now, this is a very dangerous condition and it's especially devastating in infants who are born with defects in any one of these enzymes. So if an infant is born with the defect in any one of these enzymes, that will drive the levels of ammonium leading to this condition.