So we have one bond between the 26th and the 84th 15 amino acid. We have a second bond between the we have a third bond between the 65th and 72nd, and we have the final bond between the 58th and 110th 15 amino acid in our ribonuclease. And this three dimensional structure, this confirmation basically describes the native confirmation of that ribonucleus. The native structure describes the biologically active structure of our enzyme. Now, the next question is, what did he actually want to do with these different molecules? Well, the plan was to destroy the tertiary and the secondary structures of the ribonuclease by using these appropriate agents and then to see under which conditions did the native structure of that ribonuclease basically reform.