Now, when the filtered is traveling through our nephron, it is fully secreted. That substance that ends up in the peritubular capillaries is fully secreted into our filtrate found traveling along our tubular section of that nephron. So what does that tell us about our renal clearance? Well, because none of it is actually reabsorbed, we have 125 plus 500 and that gives us 625 blood volume. Every single minute is cleared. And that means none of that substance will actually remain in our blood plasma.