Previously in our discussion on the Edmund degradation process, we alluded to the fact that the admin degradation process has its limitations. So although it's a very useful process, we cannot use the admin degradation under certain circumstances. So we said that if our polypeptide is over 50 amino acids in length, we basically cannot use this process as now the question is why? Well, the answer is simple. Just like many processes in nature, the Edmund degradation is not a perfect process and sometimes it does make a mistake, it does create an error. So it turns out that the Edmund degradation process in some cases does not release that amino acid, the first amino acid in that polypeptide chain.