And that's why we have the bicarbonate. Number three is attached. Covalently onto the carboxylase is biotin and biotin is a vitamin B seven molecule. Now, the reaction as shown on the board is actually the sum of two individual reactions. So this is actually the overall net reaction of the sum of two different reactions that are not shown on the board. But I'd like to talk about them for just a moment because they actually demonstrate the importance of biotin.