But when the binding process takes place so let's imagine this is the angiotensin two receptor. In that case, the primary messenger is angiotensin, the peptide hormone. When that peptide hormone binds onto this site here, that creates a conformational change in the structure of the green piece and then that induces a change in this orange piece. And so when that conformational change in the g alpha Q protein takes place, that's that essentially constricts this side where the GDP is found, it squeezes it out to the GDP leaves, but at the same time, it creates a pocket or region that has a high affinity for GTP guanosine triphosphate. And so a guanosine triphosphate found in a cytoplasmic side basically swimming around. And when it gets close to the cavity, as a result of that electromagnetic attraction, it will be pulled into this cavity and that will basically induce a change in the structure.