And the zymogen of plasma is Plasminogen. So plasminogen is activated by another molecule known as tissue type plasmaigen activated so TPA. So essentially Plasminogen is a Zionogen, an inactive form of plasma that has a very high affinity for Fibon. But before it actually becomes active, it must be activated by tissue tie plasminogen activated TPA. And once TPA activates plasmidogen, the plasma then locates that blood clot that consists of those fibrin molecules. And it cleaves, it breaks the peptide bond in those fibrin molecules.