Remember, tryptogen is the xiaomogen, the inactive form of trypsin. And when anteripeptidase basically proteolytically cleaves a bond in trypsin, the entire structure of the trips, ingen or not trypsin tryptogen, the entire structure of the trypsinogen changes and that creates the proper confirmation of the active side that now allows that trips and to basically carry out its activity. And what trypsin does is it activates not only for other different xiaomages, but it also activates itself. Trypsin, once activated, basically goes on to nearby tryptogen molecules and activates them to produce trypsin. So this is an amplification effect. And trypsin can also go on to activate proelastates into elastics climate trypsynogen into chimetrypsin, which we spoke about just a moment ago.