So in this ordered sequential reaction, the order at which the two substrate molecules the two reactants bind onto the active side, as well as the order at which the two products are released by the active side, actually matters. And one common example that describes an order sequential reaction is a reaction that takes place in the process of glycolysis. So remember, in Glycolysis, the ultimate goal is to basically produce pyruvate molecules and NADH molecules. Now, in the process of anaerobic respiration, we basically take the pyruvate molecules and we reduce the pyruvate molecules into lactate by using NADH. The NADH acts as a coenzyme, and it basically is transformed into NAD plus. And the enzyme that catalyzes this reaction is known as lactate dehydrogenase.