And finally, tryptophan so climate trypsin cleaves on this side of that bond. Now let's take a look at Alanine. Well, because Alanine is not a bulky hydrophobic or aromatic amino acid, what that basically means is this bond will not be cleaved by climatrypsin. Likewise, this bond will also not be cleaved because glycine is not a bulky hydrophobic or aromatic amino acid. So chimetrypsin is a serene protease that catalyzes the breaking the cleavage of peptide bond on the carboxyl side of bulky so, large hydrophobic or aromatic amino acids. Now, carmitrypsin is a serene protease and chimetrypsin is an example of an enzyme that utilizes the covalent catalysis mechanism.