Now, for this particular case, because the inhibitor does not actually bind to the active side, no matter how much we increase the substrate concentration by, that will basically not kick off our inhibitor. So that's the major difference between competitive inhibition and these two types of inhibition. Now, what exactly is Irreversible inhibition? So remember, we have reversible and irreversible. Now, Irreversible inhibition basically means that once the inhibitor binds to our enzyme, it will be extremely difficult to actually unbind that enzyme and inhibitor complex. So in this inhibition, once the inhibitor binds to the enzyme, it is very difficult to actually unbind it from that enzyme.