Now let's move on to hexokinase. So let's suppose inside our blood we have a high concentration of inside our cells we have a high concentration of ATP. So we're essentially at rest and the high amount of ATP will begin to inhibit the phosphorptokinase. Now, once phosphorkinase is inhibited, so this molecule is basically inhibited PFK is phosphorinase, then we're going to see that there is a build up of this substrate molecule that is a substrate to this enzyme fructose six phosphates. So by the way, this is step one of glycolysis, step two of glycolysis and step three of glycolysis. And once there is a build up of this molecule, because of the inhibition of this molecule by the ATP, this molecule is in equilibrium with this molecule.