Now, fumerate is important because fumerate is the link. It's the bridge between the urea cycle and gluconeogenesis, the production of glucose. So remember, in the liver we have gluconeogenesis and in gluconeogenesis we can ultimately form malate from fumerate. And malate is transformed in gluconeogenesis to oxalo acetate. And it's oxyloacetate that is used to form glucose. So we see that link, the bridge between ureacycle and gluconeogenesis, the production of glucose is this fumarate.