Ive had my items stored in my spouses house for around two weeks
and they are still there,
so, yes I believe containers in your spouses house are safe.
EDIT: They have been there for several months now without loss.
Your spouse's house is safe.
gaming.stackexchange.com/users/14575/A.C.M.
Doubtful.
Any house that is not actually one you can buy and call your own in-game would not be safe.
Except for certain exceptions, virtually all houses and buildings reset the items in them eventually.
On a relatively unrelative note, some of these exceptions are: Helgen Inn : "The ruined inn in Helgen features a wardrobe and an end table that can be used for storage, both of which do not reset.
The inn also features a perfectly preserved and functional bed.
This makes for a very useful shelter at the beginning of the game, however the fort may spawn bandits if not visited for some time."
Sleeping Giant Inn :
The chest in the secret Blades room is safe.
Best of luck.
(Source: http://www.uesp.net/wiki/Skyrim:Houses )
gaming.stackexchange.com/users/16610/MonochromaticPalette
Some containers are safe, but not all.
Luckily
the chest I put my reagents in didn't reset, but the chest I put my Ore as well as the Barrel
I put my food in both reset at least partially.
gaming.stackexchange.com/users/16635/Procylon
I wouldn't store anything in your spouses house.
After marrying uthguard the unbroken, I stored things in her house.
For a little while it worked fine, then one day I came back to empty chests, and all my loot unique items and everything else was gone!!!!On a separate note, any quest items (the type you can't remove from your inventory) remained in the chest.
I don't know if this was a glitch or not, but it sure pissed me off
gaming.stackexchange.com/users/18528/Ryan
yes it is 100% safe you should do it all the time!
it also helps if you help her first!
gaming.stackexchange.com/users/23167/sam
Is it safe to leave your stuff in your wife's house? Or will it disapear in 48 hours like anything in a dungeon?
Can stuff be put safely in your Spouse's House?
gaming.stackexchange.com
<the-elder-scrolls-5-skyrim>
gaming.stackexchange.com/questions/36301
gaming.stackexchange.com/users/14405/gameman
Containers in a spouse's house are generally safe. Most houses and buildings reset items eventually. It is an arguable point with no conclusive answer.
It is an arguable point with no conclusive answer.