### Question
How is the term DOTS-Plus defined?


### Answer
The term **DOTS-Plus** is defined in *22 U.S.C. § 2151b* as the following:

> a comprehensive tuberculosis management strategy that is built upon and works as a supplement to the standard DOTS strategy, and which takes into account specific issues (such as use of second line anti-tuberculosis drugs) that need to be addressed in areas where there is high prevalence of multi-drug resistant tuberculosis

#### Citation:
  - *22 U.S.C. § 2151b*
  - Heading: **CHAPTER 32-FOREIGN ASSISTANCE > SUBCHAPTER I-INTERNATIONAL DEVELOPMENT > Part I-Declaration of Policy; Development Assistance Authorizations**

