### Question
How does the law define supplement?


### Answer
Under *21 U.S.C. § 379g*, **supplement** is defined as:

> a request to the Secretary to approve a change in a human drug application which has been approved

#### Citation:
  - *21 U.S.C. § 379g*
  - Heading: **CHAPTER 8-NARCOTIC FARMS > SUBCHAPTER VII-GENERAL AUTHORITY > Part C-Fees > subpart 2-fees relating to drugs**

