### Question
How does the law define significant nexus?


### Answer
Under *40 CFR § 401.11*, **significant nexus** is defined as:

> that a water, including wetlands, either alone or in combination with other similarly situated waters in the region, significantly affects the chemical, physical, or biological integrity of a water identified in paragraphs (l)(1)(i) through (iii) of this section. 

#### Citation:
  - *40 CFR § 401.11*
  - Heading: **PART 401—GENERAL PROVISIONS > CHAPTER I—ENVIRONMENTAL PROTECTION AGENCY (CONTINUED)**

