Definition: In this task, you're given a statement and three sentences as choices. Your job is to determine the neutral choice based on your inference from the statement and your commonsense knowledge. The neutral choice is a sentence that neither agrees nor disagrees with the statement. Indicate your answer as '1', '2', or '3', corresponding to the choice number of the selected sentence. If sentence X agrees with sentence Y, one's correctness follows from the other one. If sentence X disagrees with sentence Y, they can not be correct at the same time.
Input: Statement: Or, are These patients the least likely to respond to interventions available in the ED? Choices: 1. These patients are the most likely to respond to interventions. 2. Do you think that these patients will be least responsive to interventions? 3. We can look at prior case studies to get an estimated impact.

3