Definition: Given an abstract of a paper, generate a title for this paper such that conveys the key focus of the paper.
Input: Abstract: The effect of tauroursodeoxycholate (TU) infusion on the plasma level and biliary transport maximum (Tm) of sulfobromophthalein (BSP) was examined in male rats during a continuous intravenous infusion of BSP with different TU infusion rates. The infusion rate of 0.6 mumol/min/100 gm body weight of TU caused significantly higher bile flow and BSP Tm values compared with the respective control values in rats with only a BSP infusion. These values, however, were significantly lower than values obtained by an equimolar infusion of taurocholate (TC). The higher infusion rates of TU (1.2 and 1.8 mumol/min/100 gm) tended to cause higher bile flow rates, but the BSP Tm value did not increase beyond the value obtained at the lower infusion rate (0.6 mumol/min/100 gm). In the highest TU infusion rate study (1.8 mumol/min/100 gm), plasma BSP concentrations were significantly higher than corresponding control values or values at a lower TU or TC infusion rate. It was concluded that in rats TU can significantly increase the BSP Tm, but to a lesser extent than TC. Furthermore, it was suggested that TU infusion at a higher rate significantly interferes with the hepatic uptake (or storage) of BSP.

Effect of tauroursodeoxycholate on the biliary transport maximum of sulfobromophthalein in the rat.