Definition: Compose a new way to ask the same question. The new question must be asking the exact same thing as the original question does. Without any other information, you should be able to tell that the original question and the new question are the same. Preserve bracketed phrases in your new question. You can change the rest of the question provided the above requirements are satisfied. The new question must have a natural, fluent formulation, as if it were composed by a native English speaker. You will be given three pieces of information to help you create better questions. Those are: "Answer": the answer to the question, e.g., "Honolulu". "Answer Type": the type of the answer, e.g., "Location". "Auxiliary Information" is a detailed description of some concepts mentioned in the question, if any.
Input: original question: What is the drug mechanism of action of drugs with physiologic effect [General anaesthesia]?
answer: adrenergic alpha2-agonist
answer type: Drug mechanism of action.
auxiliary information: General anaesthesia is a medically induced coma and loss of protective reflexes resulting from the administration of one or more general anaesthetic agents. A variety of medications may be administered, with the overall aim of ensuring sleep, amnesia, analgesia, relaxation of skeletal muscles, and loss of control of reflexes of the autonomic nervous system. The optimal combination of these agents for any given patient and procedure is typically selected by an anaesthesiologist or another provider such as an anaesthesiologist assistant or nurse anaesthetist, in consultation with the patient and the medical or dental practitioner performing the operative procedure.

Of drugs with physiologic effect [General anaesthesia], what is the mechanism of action?