Definition: In this task, you're given a statement, and three sentences as choices. Your job is to determine which sentence clearly disagrees with the statement. Indicate your answer as '1', '2', or '3' corresponding to the choice number of the selected sentence.
Input: Statement: DiClemente agreed that efficacy in the ED setting had not been totally established. Choices:  1. Success in the ED setting has not been reached. 2. DiClemente knew that efficacy was a long time away. 3. Major success was seen in the ED setting.

3