Definition: In this task, you're given a statement and three sentences as choices. Your job is to determine the neutral choice based on your inference from the statement and your commonsense knowledge. The neutral choice is a sentence that neither agrees nor disagrees with the statement. Indicate your answer as '1', '2', or '3', corresponding to the choice number of the selected sentence. If sentence X agrees with sentence Y, one's correctness follows from the other one. If sentence X disagrees with sentence Y, they can not be correct at the same time.
Input: Statement: Long before the arrival of the first Europeans, Nagasaki had been a major focus of Japan's trade with China. Choices: 1. After the Europeans came, Nagasaki no longer played an important role in Japan's trade with China. 2. Nagasaki wasn't important to Japan's trade with China until after the Europeans arrived. 3. Nagasaki played an important role in Japan's trade with China, before the Europeans came.

1