Definition: In this task, you're given a statement, and three sentences as choices. Your job is to determine which sentence clearly disagrees with the statement. Indicate your answer as '1', '2', or '3' corresponding to the choice number of the selected sentence.
Input: Statement: That is, basic substances which in combination produce--"  "Of course," Dave interrupted. Choices:  1. "I mean, simple substances that, when you put them together, make-" 2. "What? I have no idea what you're talking about," Dave interrupted. 3. "It's obvious," Dave interrupted.

2