Definition: In this task, you're given a statement and three sentences as choices. Your job is to determine the neutral choice based on your inference from the statement and your commonsense knowledge. The neutral choice is a sentence that neither agrees nor disagrees with the statement. Indicate your answer as '1', '2', or '3', corresponding to the choice number of the selected sentence. If sentence X agrees with sentence Y, one's correctness follows from the other one. If sentence X disagrees with sentence Y, they can not be correct at the same time.
Input: Statement: Patients in the emergency setting range from those with no alcohol problems to those with severe dependence. Choices: 1. The majority of patients have no problems with alcohol, however. 2. Patients never have no alcohol problems, there is always something related to alcohol in their condition.  3. The range of patients in the emergency settings goes from zero problems of alcohol to the opposite. 

1