Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: KEYWORDS Bovine Mucosal Immunology Enteric Microbiome The largest organ of the immune system is the gastrointestinal (GI) mucosa, making the management of it essential for productivity and health. The barrier that consists of mucous, defensins, and immunoglobulin A is a "kill zone" to prevent microbial invasion of the GI epithelium. The enterocytes are key cells that maintain the "kill zone" and respond to metabolites and microbial components from the lumen and signals from immune cells to maintain tight junctions and prevent "leaky gut." Passive enteric immunity is essential for disease protection of the neonate; antiinflammatory enteric response is essential disease protection for the growing and adult animal. Direct-fed microbials, including nutraceuticals, prebiotics, probiotics, and other dietary supplements, affect commensal "homeostasis" and mucosa immunity to maintain GI health.

Enteric Immunity Happy Gut, Healthy Animal