Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: Telephone: +61 7 405 974 555 Facsimile: +61 7 3636 5578 Word count Abstract 249 words Main text 2394 words Key words respiratory viruses gastrointestinal infection children real-time polymerase chain reaction cohort studies Page 2 of 33 For peer review only -http://bmjopen.bmj.com/site/about/guidelines.xhtml BMJ Open ARTICLE SUMMARY Article focus Infectious diseases are a common cause of morbidity in early childhood, even in developed economies. A diagnostic gap exists for common respiratory and gastrointestinal syndromes, with the likelihood that as yet undiscovered pathogens are involved. Existing knowledge about these common illnesses relies on research conducted before the rapid developments in molecular diagnostics of recent decades or focusses on disease at the severe end of the spectrum -hospitalisations -affecting a limited number of children and discounting the burden of more common, but less severe, community-managed illness. This protocol outlines a dynamic birth cohort study that will allow for a detailed description of the epidemiology of respiratory and gastrointestinal viruses during the first two years of life. The large biobank of specimens to be collated will act as a rich source of material to answer targeted research questions, including the role of virus acquisition and shedding on clinical illness and the discovery of new infectious agents. As study procedures, including specimen collection and return, are conducted by parents, findings will be free from Hawthorne effects from frequent interactions with study staff. Systematic weekly sampling will provide a control set of specimens for the individual and the cohort, allowing quantification of virus-specific attributable risk to illness. Non-random recruitment and enrolment requires awareness and assessment of potential bias and confounding prior to broad-based generalisation. Similar studies in the past have oversampled from higher socioeconomic households, and we attempt to avoid this by using a recruitment strategy that targets pregnant women in both public and private hospital settings. . van der Zalm MM, Uiterwaal CS, de Jong BM, et al. Viral specimen collection by parents increases response rate in population-based virus studies. J Allergy Clin Immunol 2006;117:955-6; author reply 56-7.

Title page Observational Research in Childhood Infectious Diseases (ORChID): a dynamic birth cohort study Author affiliations