Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: . High throughput screening, increased accuracy and the coupling of real-time quantitative PCR Q-PCR to robotic set-up systems are beginning to revolutionise biotechnology. Applications of Q-PCR within biotechnology are Ž . discussed with particular emphasis on the following areas of biosafety and genetic stability testing: a determination Ž . of the biodistribution of gene therapy vectors in animals; b quantification of the residual DNA in final product Ž . Ž . therapeutics; c detection of viral and bacterial nucleic acid in contaminated cell banks and final products; d Ž . quantification of the level of virus removal in process validation viral clearance studies; e specific detection of Ž . retroviral RT activity in vaccines with high sensitivity; and f transgene copy number determination for monitoring genetic stability during production. Methods employed for Q-PCR assay validation as required in ICH Topic Q2A Ž . Validation of Analytical Methods: Definitions and Terminology 1st June 1995 are also reviewed. ᮊ

Applications of quantitative PCR in the biosafety and genetic stability assessment of biotechnology products