Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: High-frequency oscillatory ventilation (HFOV) is characterized by the rapid delivery of small tidal volumes (VTs) of gas and the application of high mean airway pressures (mPaws). These characteristics make HFOV conceptually attractive as an ideal lung-protective ventilatory mode for the management of ARDS, as the high mPaws prevent cyclical derecruitment of the lung and the small VTs limit alveolar overdistension. In this review, we will summarize the literature describing the use of HFOV in adult patients with ARDS. In addition, we will discuss recent experimental studies of HFOV that have advanced our understanding of its mechanical properties. We identified 2 randomized controlled trials (RCTs) and 12 case series evaluating HFOV in adults with ARDS. In these studies, HFOV appears to be safe and consistently improves oxygenation when used as a rescue mode of ventilation in patients with severe ARDS. The two RCTs comparing HFOV to conventional ventilation revealed encouraging results but failed to show a mortality benefit of HFOV over conventional ventilation. Further research is needed to identify optimal patient selection, technique, the actual VT delivered, and the role of combining HFOV with other interventions, such as recruitment maneuvers, prone positioning, and nitric oxide. (CHEST 2007; 131:1907-1916 Abbreviations: ALI ϭ acute lung injury; APACHE ϭ acute physiology and chronic health evaluation; CMV ϭ conventional mechanical ventilation; CO ϭ cardiac output; CVP ϭ central venous pressure; Fio 2 ϭ fraction of inspired oxygen; ETT ϭ endotracheal tube; HFJV ϭ high-frequency jet ventilation; HFOV ϭ high-frequency oscillatory ventilation; HFV ϭ high-frequency ventilation; IL ϭ interleukin; iNO ϭ inhaled nitric oxide; mPaw ϭ mean airway pressure; OI ϭ oxygenation index; ⌬P ϭ pressure amplitude; PAOP ϭ pulmonary artery occlusion pressure; PCV ϭ pressure-controlled ventilation; PEEP ϭ positive end-expiratory pressure; RCT ϭ randomized controlled trial; RM ϭ recruitment maneuver; VILI ϭ ventilator-induced lung injury; Vt ϭ tidal volume

High-Frequency Oscillatory Ventilation for Adult Patients With ARDS*