Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: Severe acute respiratory syndrome (SARS) is a newly emerging infectious disease caused by a novel coronavirus (SARS-CoV), which has overwhelmed more than 30 countries claiming nearly 8400 cases with over 800 fatalities. Thanks to the unprecedented international collaboration, the whole-genomes of SARS-CoVs were successfully deciphered shortly after the identification of the causative pathogen for outbreak of SARS in southern China, in 2003. Hitherto, the SARS-CoV, as a viral paradigm of emerging infectious entities, has been extensively studied that has ranged from epidemiology, molecular virology/immunology to structural genomics. Also, several lines of breakthroughs have been record-brokenly obtained, that included the finding of ACE2, a functional receptor for the SARS-CoV, solution of the 3CL pro structure, a first crystal structure of SARS-related macromolecules, revealing of bats as natural reservoirs for SARS-like viruses and the possible involvement of civet cats in the SARS emergence. This review intends to outline the major progress in the journey of ARTICLE IN PRESS www.elsevier.com/locate/cimid 0147-9571/$ -see front matter r Re´sumeĹ e syndrome respiratoire aigu se´ve`re (SRAS ou SARS), une maladie infectieuse e´mergeante cause´e par un nouveau coronavirus (SARS-CoV), toucha plus de 8400 personnes causant 800 morts dans 30 pays diffe´rents. Graˆce a`la mise en place d'une collaboration internationale sans pre´ce´dent le de´cryptage du ge´nome complet du SARS-CoV fut re´alise´tre`s peu de temps apre`s l'identification de l'agent pathoge`ne suite au de´clenchement de l'e´pide´mie dans le sud de la Chine en 2003. Le SARS-CoV en temps que paradigme de maladies infectieuses e´mergeantes a fait l'objet d'une e´tude comple`te en passant de l'e´pide´miologie, la virologie/immunologie mole´culaire a`la ge´nomique structurale. Ainsi, c'est en un temps record qu'ont e´te´obtenues des donne´es majeures incluant la de´couverte de ACE2, un re´cepteur fonctionnel pour le SARS-CoV, la structure du 3CL pro premie`re structure cristallographique d'une macromole´cule du SARS, re´ve´lant que la chauve-souris e´tait le re´servoir naturel de virus du type SARS, et que la civette e´tait certainement a`l'origine de l'e´mergence du SRAS. Cette revue vise a`souligner les progre`s majeurs re´alise´s dans l'exploration du SRAS, en soulignant l'importance des travaux primordiaux et pre´coces re´alise´s par les chercheurs chinois. r

Towards our understanding of SARS-CoV, an emerging and devastating but quickly conquered virus