Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: To develop CpG oligodeoxynucleotides (CpG ODNs) based therapy for prevention and treatment of severe acute respiratory syndrome (SARS), we selected a novel CpG ODN (BW001), which displays B-type CpG ODN structure feature at the 5V and A-type CpG ODN structure feature at the 3V, and tested for its anti-SARS-CoV activity. We found that the supernatants of human PBMCs stimulated by BW001 significantly protected Vero cells from SARS-CoV infection. BW001 could stimulate human PBMCs and pDCs to secrete high level of IFN-a and promote human PBMCs and B cells to proliferate. Furthermore, we demonstrated that BW001 could activate CD19 + B cells and CD56 + NK cells in human PBMCs. In addition, BW001 could enhance NK cytotoxicity and IFN-g secretion in human PBMCs. Together, BW001 represents a novel type of CpG ODN and may have potential for the development of treatment and prevention for SARS as well as other viral associated diseases. D

Anti-SARS-CoV immunity induced by a novel CpG oligodeoxynucleotide