Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: The infectious dose of a virus pool of original US PEDV strain PC22A was determined in 4-day-old, cesarean-derived, colostrum-deprived (CDCD) piglets. The median pig diarrhea dose (PDD 50 ) of the virus pool was determined as 7.35 log 10 PDD 50 /mL, similar to the cell culture infectious titer, 7.75 log 10 plaque-forming units (PFU)/mL. 100 PDD 50 caused watery diarrhea in all conventional suckling piglets (n = 12) derived from a PEDV-naive sow, whereas 1000 and 10 000 PDD 50 did not cause diarrhea in piglets derived from two PEDV-field exposed-recovered sows. This information is important for future PEDV challenge studies and validation of PEDV vaccines.

Determination of the infectious titer and virulence of an original US porcine epidemic diarrhea virus PC22A strain