Definition: In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
Input: Membrane-spanning α-helices represent major sites of protein-protein interaction in membrane protein oligomerization and folding. As such, these interactions may be of exquisite specifi city. Specifi city oft en rests on a complex interplay of diff erent types of residues forming the helix-helix interfaces via dense packing and diff erent non-covalent forces, including van der Waal's forces, hydrogen bonding, charge-charge interactions, and aromatic interactions. Th ese interfaces oft en contain complex residue motifs where the contribution of constituent amino acids depends on the context of the surrounding sequence. Moreover, transmembrane helix-helix interactions are increasingly recognized as being dynamic and dependent on the functional state of a given protein. Abbreviations: GpA, glycophorin A; H-bond, hydrogen bond; TMD, transmembrane domain.

Helix-helix interaction patterns in membrane proteins