 [ Symptoms ] can a herpes blister refill after youve popped it  i messed with what seemed like an inflamed fordyce spot if it was a herpes blister would it reform a closed bump or would it simply turn into a lesion as if it popped on its own [ Disease ] it can pleurisy is an irritation of the pleura the sack covering the lungs and the inner rib wall my doc says it is like filling the area with sand