 [ Symptoms ] taken plavix for 7 years now starting 6 months ago head feels like it will explode when i bend over or cough [ Disease ] i am sorry to hear you are experiencing this if by feels like it will explode you mean you feel increased pressure in your head whenever you bend or cough this is a cause for concern as you know plavix generic name clopidogrel  is a blood thinner obviously when taking a blood thinner you do not want to break a blood vessel    especially one in your head i would advise you to see your doctor as soon as possible about this he or she will be able to determine if you should continue using the clopidogrel plavix or whether a different medication or none at all may be more appropriate for you in the meantime exercise caution when bending lifting or coughing if you need to use throat lozenges for example to calm a dry throat please do so i wish you all the best