 [ Symptoms ] can i ever have grapefruit again if i take a statin [ Disease ] we are learning more and more each day about drug interactions with food especially juices like grapefruit grapefruit juice has the ability to interact with certain enzymes in the body – the same enzymes that help break down medicines like statins so your body can use them this can lead to high levels of the drug in the body and lead to a variety of health problems it is best to avoid grapefruit while on this class of medications you can also talk to your doctor or health  care provider to see if you can be switched to a different class of medications for your cholesterol we have a few other options besides statins 