 [ Symptoms ] had total knee replacements i am not feeling good no energy depressed no appetite have lost weight [ Disease ] steroid shots can help fibro pain for several reasons 1 they reduce pain in the inflamed areas from conditions other than fibro thus one feels better overall  2 they calm down these inflamed areas thus reducing the signals that were aggravating the fibro in the immediate areas and even the overall body so indirectly the steroids calmed the fibro 3 they may directly calm down the fibro flare up perhaps by combined analgesic anti inflammatory and adrenal mechanisms involving fm 