 [ Symptoms ] has anyone experienced weight loss while on the drug topamax   my rheumatologist prescribed me topamax for migraine therapy after being on prednisone for a few months he stated that the topamax can help with with weight loss after being on the corticosteroid  has anyone else experienced weight loss with this medication  [ Disease ] yes i am also on topamax as a prevention med for complex migraine in the begining there was weight loss i was also exercising as well which made it faster cuz i was not having such terrible headache i have been on it for about 13 years do some research and if you are not already vitamin d difficent make sure that is checked regular i am not a doctor topamax is good the side affects do subside i am still on it but struggling