 [ Symptoms ] if prenatal vitamins are extra good for you when you are pregnant why not take them all the time [ Disease ] the exact cause of peyronie is disease is unknown in people whose disease develops quickly lasts a short time and goes away without treatment the likely cause is trauma hitting or bending that causes bleeding inside the penis however in some people peyronie is disease develops slowly and is severe enough to require surgical treatment other possible causes of peyronie is disease include vasculitis this is an inflammation of blood or lymphatic vessels this inflammation can lead to the formation of scar tissue connective tissue disorders according to the national institutes of health about 30 of men with peyronie is disease also develop disorders that affect the connective tissue in other parts of their bodies such as the hands and feet these conditions generally cause a thickening or hardening of the connective tissue connective tissue is specialized tissue    such as cartilage bone and skin    that acts to support other body tissues heredity some studies suggest that a man who has a relative with peyronie is disease is at greater risk for developing the disease himself