 [ Symptoms ] i am having major muscle spasms in my lower back i have been diagnosed with sciatica [ Disease ] hi you can take otc painkillers like ibuprofen naproxen along with muscle relaxant and do hot compresses if the problem is due to pinched nerve then steroid injection can have a modest effect you can also be advised anti depressants as they are also helpful in reducing pain in chronic cases you should start physiotherapy and avoid any kind of jerks to your back hope this helps