 [ Symptoms ] is it true that premature ovarian failure or pof can reverse back to normal [ Disease ] the answer here is both yes and no about half of younger women age less than 40 with a clear diagnosis of pof will experience normal function of the ovary that can come and go that is why the term ovarian insufficiency may end up as the new standard name for pof insufficiency suggests the status quo might return it is not permanent as implied by the idea of menopause 