 [ Symptoms ] can allergy shots affect sexual function  i have recently started experiencing difficulty reaching an orgasm i am on hrt and 57 years old i am trying to narrow down what might be the cause and the only change i have made has been in starting allergy shots at the first of the year    this may be a reach in my thinking i have been unable to reach my obgyn doctor to ask her questions and the information online with regard to sexually active older women is almost non existent men apparently rate #1 [ Disease ] i have never heard that allergy shots would have any adverse sexual side effects as a matter of fact i do not think it would be medically possible for this to ever happen see your ob gyn for a consultation if there is a discoverable cause for your inorgasmia it will not be your allergy shots