 [ Symptoms ] i take lexapro antidepressant can i take an over the counter medicine for my allergies [ Disease ] over the counter antihistamines are safe to take if you use lexapro but i suggest you use one that does not cause drowsiness antihistamines can cause drowsiness which can be more pronounced in someone taking a medication like lexapro always ask your pharmacist before using an over the counter medication to ensure it is safe for you i take lexapro what allergy medicine can i take