 [ Symptoms ] will taking a low dose of prednisone interfer with upcoming skin surgery male just diagnosed with severe groin itch prednisone script is 2 20mg tabs for 2 days then 1  20mg tab for 3 days i have unrelated basal cell skin surgery on nose scheduled with another doctor in 8 days will prednisone create any problmes [ Disease ] probably not but it would be wise to inform the medical provider who is performing the skin surgery for patient specific advice