 [ Symptoms ] i contracted a spinal infection and 3 operations later i have been left with a damaged spine [ Disease ] oxynorm is also oxycodone and long term use can cause dependence however other two medications are not commonly addictive but in long term each drug can cause side effects and depends on person to person so it is advisable not to take a lot of medications and discuss with your doctor to limit the intake of medications as per need hope this helps regards