 [ Symptoms ] my sore throat is causing me to lose my voice cough up phelm runny nose it hurts really bad im 28 wks pregnant sore throat lost my voice runny nose and coughing up phlem what is this and what should i do [ Disease ] that really depends on the type of blood pressure medication for instance if you took a diuretic at bed time you would be peeing all night some blood pressure medications can make you sleepy so bedtime would be best since i do not know what you are taking i would advise you to ask your medical provider or pharmacist for advice