 [ Symptoms ] i am scared that my ear drums may hurt or puncture while in flight [ Disease ] that is a safe dose but you may not be taking enough the maximum dose of ibuprofen is really 3200 mg and you are taking 400 mg since i do not know your medical history or your weight so you can address you dosage with your doctor medically you may be able to increase your dose to 600 mg each time up to 3 or 4 times per day if your arthritis warrants it