 [ Symptoms ] i keep getting sinus drainage that leads to a full blown cold why can not i get a shot of penicillin anymore [ Disease ] this caught my eye because i want to make people aware of why we do not give penicillin shots or antibiotics for colds first antibiotics do not do anything for the common cold antibiotics are only helpful if you have an infection that is caused by bacteria there has been a lot of antibiotic misuse in the u s people not taking antibiotics correctly over prescribed saving them for a rainy day and that has caused a lot of problems including the fact that good old stand by medications like penicillin are not working anymore because the bugs have become resistant  we are getting superbugs that our current antibiotics cannot touch    and this is a dangerous and important health crisis to avoid your problem in the future i would suggest proper symptom management and talking to your pharmacist about what products may be beneficial for you this may include using nasal decongestants or saline irrigation systems to help cleanse your sinus cavity and avoid the possibilities of infection i found that if i do a nasal rinse on a regular basis that i have way fewer sinus problems you could try a nettie pot or possibly just a saline solution sprayed up the nose if you ask at the pharmacy counter they can recommend not just a saline spray but also other nasal rinses that will keep the sinuses clear of all the junk that accumulates there good luck