 [ Symptoms ] severe anal and genital itching why  i have had issues with loose bowel movementsdiarrhea i went through tests including biopsies for crohns and celiac  the itch became worse more recently on the scrotum and penis the itch is an intense burning and itching sensation that can start at any time i have been taking fluconazole and it does not seem to be working 2 doses topical ointments feel as if they are causing a chemical burn on my penis sex is uncomfortable i have been married 5 yrs 20yrs previously i take humira [ Disease ] risk factors for type 1 diabetes include family history of type 1 diabetes having a family history of the disease increases the chance that a person will have islet cell antibodies but it does not predict that a person will have the disease only about 10 to 15 of people with type 1 diabetes have a family history of the disease 1 if the father has the disease a child has a 6 risk of developing it if a sibling has the disease a child has a 5 risk of developing it if the mother has the disease a child has a 2 risk of developing it if an identical twin has the disease the other twin has a 30 to 50 risk of developing it if a parent and one sibling have the disease a child has a 30 risk of developing it race white people have a greater risk for developing type 1 diabetes than black asian or hispanic people presence of islet cell antibodies in the blood people who have both a family history of type 1 diabetes and islet cell antibodies in their blood are likely to develop the disease at some time more information who develops type 1 diabetes webmd medical reference from healthwise this information is not intended to replace the advice of a doctor healthwise disclaims any liability for the decisions you make based on this information © 1995 2011 healthwise incorporated healthwise healthwise for every health decision and the healthwise logo are trademarks of healthwise incorporated