 [ Symptoms ] i had a one night stand with protection is it likely that i have contracted an std  i recently went through a bad breakup which caused me to have a little too much to drink this past weekend long story short i ended up sleeping with someone i barely knew there was protected vaginal sex and unprotected oral sex which she engaged in on me involved i know for a fact that this girl had sex with someone else two months prior to me and that i had no std beforehand i have no signs or symptoms of an std how likely is it that i contracted an std from this encounter [ Disease ] most helpful answer yes you can take antihistamines like benadryl while taking prednisone i have the same issue i asked the dermatologist and my pcp and they both said it would be safe it helped me sleep much better