 [ Symptoms ] what increases the risk of getting crohns disease [ Disease ] factors that may increase your risk of developing crohn is disease include having a family history of crohn is disease your risk increases if an immediate family member such as a parent brother or sister has the disease having ashkenazi jewish ancestry smoking cigarettes factors that may cause crohn is disease symptoms to flare up include medicines infections hormonal changes lifestyle changes including increased stress smoking webmd medical reference from healthwise this information is not intended to replace the advice of a doctor healthwise disclaims any liability for the decisions you make based on this information © 1995 2011 healthwise incorporated healthwise healthwise for every health decision and the healthwise logo are trademarks of healthwise incorporated