 [ Symptoms ] is it safe to take midol and ibuprofen together [ Disease ] midol is a brand name owned by bayer bayer manufactuers several different over the counter pain relief products under the midol name some midol products contain ibuprofen and you definitely should not take additional ibuprofen with those midol products you also should not take ibuprofen with any midol product that contains naproxyn sodium or aspirin however you can take ibuprofen with midol products that contain only acetaminophen andor pamabrom you should read the label of your midol product very carefully to determine what is in it please consult a pharmacist for assistance he or she can tell you how to read the product label and what other pain relievers you may or may not take with your specific midol product you were wise to ask this question mixing over the counter medications can often have negative consequences wishing you well