 [ Symptoms ] i am on oxygen and my nose is very dry inside what can i do to sooth it i was told not to use petroleum jelly [ Disease ] try saline nasal spray or saline gel when you are not on oxygen a cool mist humidifier in your room would be helpful as well finally drink plenty of water use a canister that hooks to the 02 machine with distilled water it puts moister with the 02 that you are receiving it prevents the nasal passage from getting to dry i am on oxygen at night and i am also take a sleeping pill i have a bottle of water on my machine and i still wake up with a headache am i doing something wrong the dr has my level set a 2