 [ Symptoms ] i am a hairdresser and the last 2 months i am experiencing painful legs constant pain [ Disease ] the quick answer to your question is yes your family members can take mucinex with tamiflu oseltamivir assuming none of them are allergic to the active ingredient in mucinex which is guaifenesin i am sorry to hear you have influenza raging through your family that is awful it is important to note that oseltamivir does not exactly cure the flu in fact in studies it only shortened the course of symptoms by about one day so your family members should not necessarily expect to feel better quickly when taking oseltamivir that said they should not stop taking the medication just because it does not seem effective yet they should take the whole course of oseltamivir which is usually given as one pill twice a day for five days meanwhile they should be ok to use other remedies such as acetaminophen tylenol ibuprofen motrin or over the counter cough and cold remedies to help them weather the symptoms of flu read labels carefully so you do not get overlapping drugs in various products for example do not mix two cough and cold remedies that both contain acetaminophen that is dangerous and do not overlook old fashioned chicken soup plenty of fluids and bed rest sometimes that is the only way to get over the flu if symptoms persist especially fever and congestion for more than five days it is probably a good idea to check back with the doctor if any adult spikes a high fever over 101f that is a good reason to take a trip to the emergency room next year flu shots for everyone prevention is always your best approach wishing you well