 [ Symptoms ] i am feel a constant desire to urinate no fever no pain and no burning or discomfort what could be happening  no fever no pain and no discomfort just the sensation that i am holding it [ Disease ] you can not blame the low doses of hrt in use today for midlife weight gain at least not for any more than a few pounds you do get a little more bloated on it but it does not cause body fat accumulation overeating not exercising and stress do