 [ Symptoms ] i am take synthroid 75 mcgm every day my dr prescribed phentermine 37 5 when should i take each so for best benefit  i am not sure when to take my synthroid and when to take the phentermine so that they do not effect one another [ Disease ] i am glad you are aware of the abcde rule there is some of your points in favor to and some are against let me tell you that you should be suspicious due to the changes but it s only one mole changes and of v small size are you sure that there is no other hidden moles elsewhere anyways u ll never be sure about the criteria except after being totally fully examined and with undergoing punch or excisional biopsy…