 [ Symptoms ] has anyone experienced weight loss while on the drug topamax   my rheumatologist prescribed me topamax for migraine therapy after being on prednisone for a few months he stated that the topamax can help with with weight loss after being on the corticosteroid  has anyone else experienced weight loss with this medication  [ Disease ] the good news is that bright red blood on the surface of your stool or in the toilet water or on the toilet paper usually is not the type of blood associated with a cancer of the digestive tract usually bright red blood like that is more associated with hemorrhoids or a minor rectal bleed due to passing hard stool or straining hard during a bowel movement when we talk about blood in the stool related to a cancer this blood usually is not recognizable as blood it usually turns the stool black or tarry the pain in your upper right abdomen could be caused by many conditions including gallstones because the pain has persisted for over 2 weeks i would suggest you get it checked out the pain may or may not be related to the other symptoms you describe only a medical professional can give you a firm diagnosis i hope you feel better soon