 [ Symptoms ] can i reduce weight by going to gym [ Disease ] this is a good question i am glad you asked first i want to caution you that no one should put themselves on low dose aspirin therapy without consulting a physician many people have heard that taking a daily aspirin may be good for their heart or for helping prevent colon cancer but taking a daily aspirin should only be done on doctor is orders so please if your health care provider did not tell you take a daily aspirin consult your provider before you begin self treating many people in fact should not take aspirin at all your health care provider who knows your complete medical history is the person in the best position to advise you whether or not taking a daily aspirin is right for you as to your question it really should not matter if you take aspirin with food or on an empty stomach if you are prone to stomach upset when taking aspirin in the past then you can take it with food hope this helps