 [ Symptoms ] what would cause someone is brain to start hurting during intercourse [ Disease ] this is an interesting question thanks for asking it is impossible to give you a definitive answer without having more information for example when you say brain pain  do you mean a headache is the person getting the headache a man or a woman what is the age of the person one possibility that immediately springs to mind is high blood pressure during sex especially during vigorous sex blood pressure can rise this rise in pressure can cause a temporary headache the headache could begin during sexual intercourse or afterwards if this happens frequently or if the person experiencing the headache is using a medication for erectile dysfunction such as viagra or cialis it would be wise to speak to your health care professional about the issue please do not be embarrassed to seek medical attention about this issue trust me health care providers have the utmost respect for patients who are willing to be open and honest about their health needs take care