 [ Symptoms ] i had mono when i was younger so i guess i still have the epstein barr virus could that have caused my pleurisy  i was recently admitted to the er for severe stabbing neck and chest pains and extreme shortness of breath all tests came back normal the diagnosis became possible pleurisy but i did not get a whole lot of answers about what could have caused it the dr did ask if i had ever had mono and i said yes but then he changed the topic so i did research and saw on some pages that epstein barr virus could cause pleurisy is this truelikely  thanks [ Disease ] it is not very likely that your ebv is the cause of your pleurisy there are many causes mainly other viruses that can be responsible