 [ Symptoms ] how long should a patient wait after getting the shingles vaccine to begin an antibiotic if they develop a uti [ Disease ] my opinion it has to do with the fact that you just strenuously exercised the muscles in your legs and with going to bed right after you did not give your muscles proper time to relax with a good stretching period after your workout they are probably cramping and tightening up i would suggest you try to hydrate before during and after your workout and give yourself a good 10 minute stretching cool down before heading to bed