 [ Symptoms ] is there a connection between ehlers danlos syndrome eds and fibromyalgia [ Disease ] yes there is a relationship between ehlers danlos eds and fm inherited connective tissue disorders including eds marfan is and joint hypermobility syndrome often lead to fm as well i consider this to be a reactive fm or secondary fm as opposed to fm all by itself or primary fm reactive fm acts like any other fm and needs its own special attention in addition to treating the connective tissue disorder in the case of eds most commonly this follows an autosomal dominant inheritance pattern so that means 50 of the offspring are at risk statistically of inheriting eds reactive fm is not automatic in everyone with connective tissue diseases but i see them commonly together 