 [ Symptoms ] with lyme disease does the red target like rash appear only at the site of the bite or multiple places  i have developed several target shaped red circular rash areas along with the other symptoms my though was lyme disease i have the rashes is multiple and varied locations [ Disease ] yes some antidepressants and cardiac medications can interfere with sexual activity so please discuss this openly with your doctor since i do not know what meds are you are taking the size of your penis should not be drastically changing no more than your hands or feet getting smaller it may seem that way if you are having erectile problems this is another common male disorder that may be able to be rectified but any use of ed meds will need to be prescribed by your doctor    someone who knows your medical history the medications you are taking and can examine you