 [ Symptoms ] is it safe to take over the counter cold medicine for multiple symptoms along with dextromethorphan for a severe cough [ Disease ] you have to be careful when mixing over the counter cold medicines as a pharmacist i tend to tell my patients to avoid products that treat multiple symptoms and contain several ingredients when you use these products you often end up taking something for a symptom you do not have also you may end up taking too much of one type of ingredient if you mix products i do not know what cold medicine you took or if that medicine contained a cough suppressant therefore i could not tell you if it was ok to use dextromethorphan with it i suggest you take the products to a pharmacist who can review them with you to make sure you do not overdo it