 [ Symptoms ] is klonopin a mao inhibitor can you take both clonazepam klonopin and amitriptyline together [ Disease ] neither klonopin clonazepam nor amitriptyline is an mao monoamineoxidase inhibitor but that does not mean you should mix them clonazepam klonopin is a benzodiazepine that means it is in the same class of anti anxiety drugs as valium it is also used to treat seizures and panic attacks amitriptyline is a tricyclic antidepressant tricyclic antidepressants are the oldest of the antidepressant medications amitriptyline helps elevate mood if your health care provider has prescribed both clonazepam and amitriptyline for you then he or she feels they are safe for you to take however no one should combine medications without the advice of a physician nurse practitioner or pharmacist if you have any questions about medications your health care provider has prescribed for you you would be well advised to make an appointment to discuss all your medications with your provider he or she can explain what each medication is for and make sure that none of your medications conflict with each other i hope this information helps