 [ Symptoms ] diffuse large b cell lymphoma – primary mediastima  abnormal non mass like circumferential mucosal hyperdensity present [ Disease ] how big are their nipples perhaps it is time for them to start wearing some sort of bra how much exercise do they regularly get i am a guy and i am in pretty great shape but if i run for a few hours a day every day after taking several weeks off my nipples can get sore from my shirt i imagine it could be the very same problem for a very young girl depending on how much and what type of exercise they are getting