 [ Symptoms ] i am taking omeprazole 20 mg and norvasc 10 mg can i take zantac with them [ Disease ] this is a good example of a duplication of therapy you cannot take omeprazole and zantac because they both try to do the same thing decrease the amount of acid in the stomach i would ask what symptoms you are having that make you think you need the zantac most likely i would recommend you calling your health care provider to alert them to your symptoms they may want to re evaluate your condition and medications