 [ Symptoms ] what allergy medications are safe to use during pregnancy [ Disease ] i always typically refer my pregnant moms to make sure that they talk to their healthcare provider first because they might have a particular brand that they are comfortable with i always typically refer my pregnant moms to make sure that they talk to their healthcare provider first because they might have a particular brand that they are comfortable with there is another product out on the market called chlor trimeton and that is an older medication very similar to benadryl that is still available and that has great data with it because it was actually tested in pregnancy and that is considered very safe and effective zyrtec and claritin are other alternatives that could be used but once again i do stress though the fact that they should really call their healthcare provider first and see what they prefer as far as the drug to treat with now if they have a stuffy nose it is a little different subject because nasal decongestants are not as safe in pregnant women and typically they have to use a saline nasal spray which i know is difficult because it may not relieve the congestion as much but it is really the safest thing for them to use