 [ Symptoms ] how do you lose weight if you are supposed to eat 1500 calories but only excerise 300 of it away daily  i am just trying to understand the concept of being told that i need to eat a minimum of 1500 calories daily drink 64 ounces of water daily and exercise at least 300 calories daily [ Disease ] a granulomatous reaction is a skin reaction caused by drugs called iodides and bromides