 [ Symptoms ] about 6 months ago i got a catheter due to urinary retention from benadryl will vistaril do the same  i took 40 pills of benadryl 1000 mg and had to have a catheter installed to drain my bladder will taking one hydtoxyzine 25 mg give me urinary retention [ Disease ] maybe both are in the antihistamine class consult your medical provider or urologist for patient specific advice in this matter but avoiding hydroxyzine may be advisable since it may cause a similar urinary retention issue