 [ Symptoms ] i have on going dull knee pains for over two years [ Disease ] the big joints inflammation is usually occuring with autoimmune disorders like rheumatiod arthritis and systemic lupus i̇nvestigations will be able to show us what is going on crp is an initial test plain xray on the knee knowing that arthropathy and arthralgia are one of the complications of hemochromatosis it is advised to rule out other pathologies and having a close follow up with your doctor for the medicationsdiet for treating the iron toxicity