 [ Symptoms ] i have autoimmune hepatitis i got the hepatitis b vaccination will it make a difference or did i waste my time [ Disease ] people with chronic liver disease can experience a severe if not life threatening course of disease when infected with acute hepatitis a or b and some people who have had a liver transplant are at risk for developing hepatitis b which could lead to dysfunction of the transplanted liver fulminant hepatitis andor cirrhosis it is of utmost importance that all people with chronic liver disease receive the immunizations for hepatitis a and b