 [ Symptoms ] can quiting smoking cause joint pain i recently quit smoking and since i have quit i noticed that i am having leg pain and pain in my joints such as my ankles elbows fingers could this be related to my quitting [ Disease ] i would love to know this as well i have both a very low ige as well as am pge2 deficient they do not play nicely together and the only way i have been told there are infusionsintravenous immunoglobulin therapy one can take to help but i guess that would depend upon how badly your body is in need of this i merely take a lot of benadryl and sadly always have to have prednisone on hand for when the flare ups get too bad sadly most of the current research is to lower ige not raise it