 [ Symptoms ] is it okay to give my son benadryl and advil for his runny nose sinus pressure and headache [ Disease ] the most important piece of information that i need to know is how old is the child and how much does he weigh  i will also need to know what other medications you may have given him i would recommend tylenol or an acetaminophen product to start for the headache i would also ask a few more questions about the sinus pressure to define it more benadryl is ok but i would probably recommend a claritin or zyrtec type product because they work longer and have less side effects