 [ Symptoms ] can an abscessed tooth lead to cellulitis  toothache lead to facial swelling extending to the submandibular region causing difficulty swallowing im rocephin 1g administered will that need to be followed up with pen vk 1000mg [ Disease ] rocephin is very appropriate for cellulitis but may need more than just one injection we often give one injection a day for three days depending on the severity of the cellulitis and response and yes it is very important to remain on oral antibiotics for a period of time until the cellulitis has resolved penicillin is only one of the many choices that can be used