 [ Symptoms ] one depo shot on nov 20 2012 next shot was due feb 20 2013 have not had a period since january i am really worried is it normal i do not think that i am pregnant but i have taken two pregnancy tests both showed up negative i am always moody stressed out and cramp a lot also i am 20 years old i have been on the depo before but it made my period heavy and light for 3 weeks at a time if not longer afterwards it went back to normal  [ Disease ] it can but i never say it is anxiety until after there is been a full medical exam to rule out anything physical you should consider doing this and also take a look to see if you might be experiencing undue stress lack of sleep or anything else that might have triggered this