 [ Symptoms ] any medications that could adversely effect a womans libidoto causingno desire at all to have sex for past ten years  in 2002 my wife was diagnosed with borderline personality disorder and bi polar 2 she was prescribed lithium 300 mgday alprazolam xr 1 mg in am and 2 mg at night 200 mg wellbutrin daily is it possible thatone or a combination of any of these could cause a loss of all interest in sea [ Disease ] yes chances are there for loss in sex drive when taking anti anxiety medications