 [ Symptoms ] had neck surg   will vicodin increase bp i normally have low bp but it is now 150 100 had diskectomy a week ago   normally have pretty low bp    at least 2 times i have had my bp spike pretty high   i e 150 over 105 will the vicodin cause this   i normally take metopropol 25mg 1 x per nite   which i have taken several hours ago and it is still high reading [ Disease ] i am sorry to hear you are going through this vicodin generic name hydrocodone acetaminophen should not cause your blood pressure to spike quite the opposite in fact pain can cause your blood pressure to go up though so be sure to take enough medication to keep your pain adequately controlled several things can cause your blood pressure to spike temporarily including needing to urinate pee however if your post operative pressure is consistently above what is normal for you please call your surgeon is office to advise them about what is going on they need to know i wish you all the best with this