 [ Symptoms ] does it matter what time of day you take vit d suppliments or any suppliments for that matter  i was diagnosed with low to no vit d in my body and was wondering also can this affect mood such depression and anxiety attacks thanks for your help [ Disease ] there are no drug interactions to be concerned about between the c phen dm and the acetaminophen found in tylenol the two medications can be given together anytime you have questions about mixing medications you should always consult your pharmacist