 [ Symptoms ] i collapsed and had a back spasm i have terrible pain in back and spine [ Disease ] it depends on your symptoms antihistamines generally relieve allergy type symptoms like itchy and watery eyes runny nose sneezing and itchy throat decongestants are helpful to relieve sinus congestion and pressure as well as nasal congestion rule of thumb you want to take the smallest number of medications to treat most of your symptoms and to minimize the number of potential side effects so if you have runny nose and watery eyes and no congestion an antihistamine only product is a good choice if you ever have questions about which over the counter medication to choose ask your pharmacist