 [ Symptoms ] i have a large bump under skin in my wrist it dont have any pain or tenderness what can it be it just appeared a few days ago not sure if i could go to dr or not [ Disease ] everyone has a different level of energy so radiation treatment will affect each patient differently patients frequently experience fatigue after several weeks of treatment for most patients this fatigue is mild however a loss of energy may require other patients to change their daily routine if your doctor thinks it may be necessary for you to limit your activity he or she will discuss it with you to minimize fatigue while you are receiving radiation treatment be sure to get enough rest eat a well balanced nutritious diet pace your activities and plan frequent rest periods