 [ Symptoms ] i got first shot of depo in febuary24 in the morning and we had sex in the feb24 at night is shot works immediately  i was wondering because pregnancy for now is not an option  and also i would like to ask after your first shot how long it will be effective in your body that you are 99 protective  before i was taking depo but i always had my menstruation every month but this time i dont had my means [ Disease ] hi have a read of this link from webmd gives you all your answers you want the link <link> do hope this helps you good luck