 [ Symptoms ] my 23 yo son developed a 2 inch lump at the base of the skull just above the hairline the lump is tender and red and directly in the center of his head where the spine ends [ Disease ] even in people with chronic hepatitis b the immune system is working to suppress the virus medications that suppress the immune system allow the virus to reproduce in large numbers and may cause the hepatitis to flare examples of medications that suppress the immune system are prednisone used to treat many diseases including asthma inflammatory bowel disease and certain types of skin disease and arthritis methotrexate rheumatrex trexall used to treat certain types of skin disease arthritis and cancer cyclophosphamide cytoxan used to treat some cancers if an immunosuppressant drug is stopped the body is immune system is activity may rebound and cause severe inflammation of the liver