 [ Symptoms ] prozac does not work for my depression and anxiety anymore condition worsened i am 43yo female i have been taking prozac for about 20 yrs now for depression and anxiety within the past couple of years my condition has resurfaced and worsened therapy has not helped i do not do drugs and rarely drink i am not suicidal but have no will to perform every day tasks or even want to leave my house i am a stay at home mom and feel like a robot just doing what i have to do for the kids i have lost any interest in enjoying life [ Disease ] you can not really rule out lung cancer but it likely would not be caused by your therapy or the x rays you can help your compromised immune system plus the depression by getting plenty of antioxidant rich foods and exercising at least a few times a week it may not be a cure but it will be a complement to your other treatments