 [ Symptoms ] is there a safe medication to make my 30 pound baby sleepy for air travel we are going to be on an airplane for 9 hours is there anything i can give her to make her sleepy [ Disease ] maybe but you will need to address this problem with your baby is pediatrician    someone who knows her and her medical history this issue is always a challenge for parents traveling with babies some have used benadryl but i am not a big fan of doing this since this medication which will make adults sleepy can result in a paradoxical effect in children in other words it could cause her to be stimulated like you gave her coffee you do not want a wild and stimulated baby on a nine hour flight talk to the pediatrician