 [ Symptoms ] can i take pyridium while taking cipro can i take pyridium while on cipro for a bacterial infection i also am taking aveno sitz baths [ Disease ] smoking adversely affects that stomach for instance smokers have a higher incidence of stomach ulcers so it would not surprise me that your smoking is causing issues in your esophagus and stomach your body is sending you a message to stop smoking a wise person would listen and comply