 [ Symptoms ] what causes infertility in women [ Disease ] problems with ovulation account for most cases of infertility in women without ovulation there are no eggs to be fertilized some signs that a woman is not ovulating normally include irregular or absent menstrual periods less common causes of fertility problems in women include blocked fallopian tubes due to pelvic inflammatory disease endometriosis or surgery for an ectopic pregnancy physical problems with the uterus uterine fibroids