 [ Symptoms ] i have been prescribed medications by two doctors are they all safe to take together  these medicines include singulair 10 mg 1xday prednisone 40 mg 1xday flonase adipex claritin d 24 hour and lansoprazole dr 30 bid [ Disease ] loose skin around the knees may be part of the natural aging process extreme weight loss may lead to excess skin these issues may be addressed by a plastic surgeon excess sun exposure is the no 1 cause of premature aging and wrinkling of the skin if you suffer from chronic swelling around your knees compression garments and support hose may be beneficial