 [ Symptoms ] awake during colonoscopy reason given was tolerance to my nueropathy and anxiety meds is this possible  meds are clonazepam and duloxetine just added gabapentin [ Disease ] unfortunately you are not alone my last colonoscopy and endoscopy i was wide awake and felt everything it was not fun to say the least i recently had a endoscopy and the nurse said a few of the other nurses had the procedure without any meds she also stated they have patients who have requested no medication it was very uncomfortable to say the least i am on a fentanyl patch so it is very hard to sedate me