 [ Symptoms ] can antibiotic use over 6 months create a more chronic nausea bowel urgency and anxiety after use  i am 35 and in february was bit by a spider on my face and ended up with a staph infection and on clindamycin for 12 weeks right after got my first kidney stone and pyleonephritis and treated with cipro now two months later with a residual nauseous stomach and bowel irregularities urgency and feeling of anxiety due to chronic nausea and bowel issues probiotics do not to seem to be helping [ Disease ] hi well your sex was in the safe period of her cycle as for her periods with not being regular does not help sounds like going on the bc pill would regulate her and you would be having safe sex if she lets you hope this helps you both good luck ps remember safe sex is the best sex