 [ Symptoms ] can i treat pain from mouth uclers using advil ibuprofen i have been experiencing pain from mouth ulcers for a few days now and i was just wondering if it was possible to treat the pain with advil and if it would make a difference if i used it or not [ Disease ] you can take advil for mouth ulcers aphthous stomatitis or canker sores since this medication is anti inflammatory this can help relieve some of the discomfort until they naturally go away