 [ Symptoms ] does ulcerative colitis lead to colon cancer [ Disease ] having uc or crohn is disease increases the risk of developing colorectal cancer but most people more than 90 with inflammatory bowel disease do not develop cancer the american cancer society recommends that people with uc and crohn is have a screening colonoscopy eight years after diagnosis if the entire large intestine is involved and 12 to 15 years after diagnosis if only the left part of it is affected follow up colonoscopy screening should occur every one to two years after that