 [ Symptoms ] can wearing tight jeans cause numbness on my right thigh [ Disease ] i think it is possible i have seen some very tight jeans in my practice in order to know for sure why not switch to looser pants or a different non constrictive outfit to see if the numbness improves because there can be other causes of numbness i have no way of knowning specifically if this is the sole cause in your case unless i had the opportunity to examine you