 [ Symptoms ] i am taking ortho tri cyclen lo and was just prescribed caziant oral how do these two prescriptions compare [ Disease ] caziant and ortho tri cyclen lo are both birth control pills that contain a combination of estrogen and progestins known as tri phasic oral contraceptives this means that each pill pack has three different strengths of hormones the difference between these two brands is that ortho tri cyclen lo contains norgestimate and caziant contains desogestrel – two similar but different version of progestin as far as efficacy goes they are equally effective although you should not notice much difference if you experience any changes in how you feel you should talk to your health care provider