 [ Symptoms ] had extreme reaction to pneumonia shot 5 days ago and now granddaughter has a fever   is there a connection  i did not realize i was having strong reaction to pneumonia shot   headache pain at site as well as redness and swelling tiredness   do not know if i had a fever but still have some redness and swelling after 5 days i am weekday care giver for my granddaughters and now the 2 12 yr old has a fever is there a connection [ Disease ] knee and hip replacements consisting of metal on metal may cause a condition called metallosis this side effect happens when rubbing of the metal implanted surfaces results in chromium and cobalt particles accumulating in the blood stream to toxic levels some cobalt & chromium is normally found in the blood stream to carry out routine cellular actions the recommended treatment for metallosis is a complete surgical revision removing the implant and installing a new implant of the knee or hip