 [ Symptoms ] my immune system is deficient in the 1gg3 classification please advise [ Disease ] your immune deficiency condition makes you more liable to experience more frequent infections discuss with your specialist the options of infection control life style modifications and even prophylactic antibiotics if neededseek the er help if you find yourself with obvious increase in the work of breathing high grade fever above 38 shortness of breathing not responding to treatment may be you need a specific regimen of cortisone and beta 2 agonist to relieve your asthma symptoms as well you need a team of both immunologist and pulmonologistgood luck