 [ Symptoms ] if i have already given my 6 year old benadryl and tylenol and she now has fever can i now give her motrin [ Disease ] what are you treating fevers in children are not dangerous as a matter of fact fevers are therapeutic by helping to fight infection the only reason to give a child ibuprofen or acetaminophen would be for comfort and it is certainly okay to do that many people    mostly those fearful of fever    use both alternating acetaminophen and ibuprofen but studies have not proven that this is really necessary is it safe probably they are two different drugs i tell my patient to just pick one and use it sparingly if they want me to choose i go for the ibuprofen it lasts longer is anti inflammatory and is safer benadryl use in children is iffy too it can dry up a runny nose for 2 4 hours but then it wears off and has to be repeated again in adults benadryl can make you sleepy but in children it can actually stimulate them this is called a paradoxical effect benadryl is safe if your child is not having any adverse effects