 [ Symptoms ] severe anal and genital itching why  i have had issues with loose bowel movementsdiarrhea i went through tests including biopsies for crohns and celiac  the itch became worse more recently on the scrotum and penis the itch is an intense burning and itching sensation that can start at any time i have been taking fluconazole and it does not seem to be working 2 doses topical ointments feel as if they are causing a chemical burn on my penis sex is uncomfortable i have been married 5 yrs 20yrs previously i take humira [ Disease ] i am sorry to hear you are going through this it sounds very unpleasant and i applaud you for having what could be an embarrassing situation checked out by a medical professional i guess i am going to assume you have been tested for sexually transmitted diseases stds several stds can cause these types of symptoms i urge you to continue seeking medical attention until you get a good diagnosis and treatment plan there is obviously something wrong and it may take real persistence on your part to keep your providers moving forward in trying to diagnose this if necessary get a referral to a urologist even though the symptoms seem to be external wishing you well