 [ Symptoms ] what is paget is disease [ Disease ] paget is disease is a chronic condition of bone characterized by disorder of the normal bone remodeling process normal bone has a balance of forces that act to lay down new bone and take up old bone this relationship referred to as bone remodeling is essential for maintaining the normal calcium levels in our blood in bone affected by paget is disease the bone remodeling is disturbed and not synchronized as a result the bone that is formed is abnormal enlarged not as dense brittle and prone to breakage fracture paget is disease affects older skeletal bone of adults it is estimated that 1 of adults in the u s have paget is disease there is also an extremely rare form of paget is disease in children referred to as juvenile paget is disease paget is disease is also known as osteitis deformans