 [ Symptoms ] how do i kinow if the pain in my calf is a blood clot  i have had pain in the center of my calf for about 48 hours it is not red or hot but the pain feels like a charlie horse that will not go away [ Disease ] if you suspect you might have a blood clot you should make an appointment with your doctor as soon as possible you have a good grasp of the primary symptoms of deep vein thrombosis dvt but just because you do not have the redness and heat does not mean it is not a dvt of course pain in one calf muscle does not necessarily mean you do have a dvt either generally dvt is first assessed using a non invasive ultrasound test this imaging test will give your doctor a good look at your veins to see if one of them may be blocked or partially blocked if you do have a blood clot in your leg your doctor may treat it with medications best wishes getting this sorted out i had an ultra sound and it showed a blood clot