 [ Symptoms ] pain in chest with palpable lump no diagnosis can be made [ Disease ] hi strawdine hi this info is from webmd common allergic reactions to penicillin include rashes hives itchy eyes and swollen lips tongue or face in rare cases an allergy to penicillin can cause an anaphylactic reaction which can be deadly this type of reaction usually happens within an hour after you take penicillin symptoms include difficulty breathing hives wheezing dizziness loss of consciousness rapid or weak pulses skin turning blue diarrhea nausea and vomiting if you think you are having an anaphylactic reaction call 911 immediately now as you can read it is a very rare reaction and her question was probabley 24 hours later way past what you had good luck