 [ Symptoms ] debilitating back pain unable to do anything tests show connective tissue disease [ Disease ] connective tissue diseases are actually a group of medical diseasese it is any disease that has the connective tissues of the body as a primary target of pathology many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one is own body tissues autoimmunity i̇t is not always a cause of death it is a cause of limitation that can be lived with by taking meducations and physiotherapy if needed see a rheumatologist regards