 [ Symptoms ] itching in hands feet & lower legs it feels like skin & interior antihis controls it a few hours cause what do i do  i have had this severe itching for 3 days i am not diabetic  topical cortisone 1 cream helps but i would like to know how i can stop whatever is causing this itch [ Disease ] most helpful answer there may be hundreds of possible allergic causes it would be impossible to determine which one or more allergens without an extensive medical history and perhaps some allergy testing in the meantime consider taking a long acting antihistamine claritin zyrtec allegra since whatever is causing this reaction is still in your midst