 [ Symptoms ] can i take a cough medicine when im taking clindamycin hcl 150 mg [ Disease ] i am sorry to hear you are going through this it is annoying when our joints do not work correctly you may be spot on when you say your knee joint feels like it is full of fluid that could be exactly what is going on many things can cause the knee joint to temporarily fill up with fluid as long as you have no signs of a deep vein thrombosis dvt such as heat pain and angry redness to the calf area you probably can take a wait and see attitude if the pressure and stiffness in your knee is accompanied by a lump on the back of your knee where the leg bends you could have a baker is cyst this type of cyst can be caused by osteoarthritis or an injury a baker is cyst can be easily diagnosed by mri though some medical professionals can tell simply with a physical examination these cysts often are easy to feel since you do not have a fever you can be relatively assured there is no infection process going on if resting and elevating the knee do not cause the pressure to go away you should consider a visit to your primary care provider for an evaluation wishing you well