 [ Symptoms ] girlfriend in pain lower right abdomen pinching pain vomiting occasional reddish urine sudden sharp pain at first okay so my girlfriend recently had this sharp pain in her lower right abdomen area around the illeumappendix area and it goes from the right lower side all the way across to the lower left abdomen it started off as a sudden and sharp pain out of nowhere she was barely able to walk or sitlay down comfortably her urine was reddish a few days ago when it first happened but has not been odd lately just tonight she started vomiting and said she had been nauseous on and off all day [ Disease ] only women who no longer have a uterus should consider using estrogen alone therapy et for women with a uterus the option they might consider is estrogen plus progestogen therapy ept progestogen is needed to protect the uterus and balance the effects of estrogen using et alone for 5 or more years can more than triple the risk of developing cancer of the uterus but adding progestogen prevents the uterine lining endometrium from thickening and greatly reduces the cancer risk then of course each woman must determine with her healthcare provider if ept is right for her