 [ Symptoms ] does metformin cause low libido in men i am currently taking 500 mgm of metformin twice a day for border line diabetes type 2 in addition i take lipitor 20 gms at night plus 1 25 gms of altace ramipril  i have very low desire for sex i am 65 years old and had a triple coronary by pass about 5 years ago i am still physically active and exercise 30 mins on an elliptical 3to4 times a week are the medications i am taking the cause of low libido [ Disease ] diabetes itself can cause changes in sexual desire libido as well as age but i would not think that your medications would be high a very complex list of many other possible causes please consult your primary care medical provider for a proper evaluation and some help