 [ Symptoms ] i am taking the lupron depo for endometrosis i have symptoms of vaginal clots and mucus dizziness and nausea why  i was diagnosed over a year ago with endometriosis and took the lupron depo shots for 5 months nine months later i was placed back on the lupron depo shot since taking the shot i have had very thick mucus and dark brown discharge when i urinate i have been very dizzy and nauseous after only 2 days of taking the shot why is this i did not have this happen the first time that i was on the lupron depo [ Disease ] hi it looks like bowel inflammation like irritable bowel syndrome consult a gastroenterologist and get evaluated you should take plenty of probiotics like yogurt and take small frequent meals avoid large spicy meals and also limit intake of tea coffee and other acidic foods drink plenty of water and do moderate workout to improve metabolism hope this helps