 [ Symptoms ] i am beginning to notice that i am losing strength in my hands things fall out of them what is wrong with me  if i am holding on to something and apply medium low pressure it slips out my hands or i just can not maintain grip when i become upset or angry my hands swell up noticeably and the condition worsens i am 31 years old 32 in january hispanic 61 255 lbs heart disease and diabetes run in my family please tell me what could be wrong with me   [ Disease ] i am sorry to hear you are going through this it sounds very distressing unfortunately the only way to diagnose what is causing this problem is by physical examination i suggest you consult your primary health care provider to discuss your symptoms and have some testing done a number of conditions can cause the symptoms you describe so please do not jump to any dire conclusions until you see a medical professional take care