 [ Symptoms ] what are the long term effects of estrogen overdose in a dog  my dog was on synthetic estrogen for about 5 years i used over the counter estroven for humans 12 pill daily my 1st vet was ok with it she is been off the estrogen for 2 yrs we have seen 3 more vets since issues are she is bald except for her head and her rear joints are deteriorating fast she is 9 yrs old no success in help for baldness or joint issues could long term od of estroven be the cause [ Disease ] the ultimate goals of antiviral therapy are to eliminate hepatitis c virus improve or normalize the liver tests and histology microscopic appearance prevent progression to cirrhosis and liver cancer prolong survival and improve the quality of life only a sustained virologic response provides the possibility of achieving all of the ultimate goals since most patients who have a sustained viruolgic response will remain in remission indefinitely the rest of the patients non responders partial responders and relapsers may show improvement in blood tests with or without relief of symptoms