 [ Symptoms ] mupirocin is not working it is been more than 5 days and my face condition is worse why will not it go away  i have had this face infection for about 4 months dr has diagnosed it as staph but the clindamycin phosphate has not been working in those 4 months  mupirocin is not working either when i had impetigo before it was a miracle worker now it is worse on my chin and corner of my mouth i have warm and red areas that ooze and crust  i have been faithful in applying my ointments maintaining hygiene etc help me please [ Disease ] most helpful answer i have no way of confirming your diagnosis since i can not examine your face mupirocin is a great topical that covers both staph and strep but if your infection is deeper in the tissue you may need a systemic oral antibiotic again or you may have something other than impetigo seeing a dermatologist may be an appropriate next step since your doctor is treatment for the last four months has not been effective