 [ Symptoms ] i am 22 weeks pregnant and have a cold is it alright to take tylenol pm [ Disease ] i would not advise taking tylenol pm while you are pregnant due to the fact that it contains an antihistamine that is not recommended during pregnancy it would be helpful to know your symptoms so we do not over treat  unfortunately due to the fact that you are pregnant your options are limited if you have a stuffy nose you can use a saline nasal spray like ocean or ayr i would also recommend running a vaporizer in your bedroom