 [ Symptoms ] can the active ingredent diphenhydramine in advil pm cause a false positive drug screen for benzodiazepine  i did a little research myself & need some clarification please i was experiencing chronic back pain so i was taking advil during the day & advil pm at night for a length of time & i came back positive for benzodiazepines on a urine test [ Disease ] my unprofessional advice yes just to check it out if nothing else you have to be careful with anything so near the brain my brother ignored his pain and by the time he finally did something his jaw pain had turned into an abscess that moved into his face head eyes he very nearly died