 [ Symptoms ] Which medicine to take if I get a mild fever? [ Disease ] To treat a fever at home: 1)Drink plenty of fluids to stay hydrated. 2)Dress in lightweight clothing. 3)Use a light blanket if you feel chilled, until the chills end. 4)Take acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin IB, others). 5) Get medical help if the fever lasts more than five days in a row.