 [ Symptoms ] How do you treat a blocked nose? [ Disease ] When youâ€™re stuffed up, focus on keeping your nasal passages and sinuses moist. To keep your nasal passages moist, you can: 1)Use a humidifier or vaporizer. 2)Drink lots of fluids. This will thin out your mucus, which could help prevent blocked sinuses. 3)Place a warm, wet towel on your face. It may relieve discomfort and open your nasal passages.