passages: 974
passages: document
passages: Cophenylcaine spray vs. placebo in flexible nasendoscopy : a prospective double-blind randomised controlled trial . Practices vary across the UK on the use of topical preparation prior to flexible fibreoptic nasendoscopy . In this double-blind study , we randomised 98 patients to receive cophenylcaine or placebo nasal spray before flexible nasendoscopy . A visual analogue scale ( 1-100 ) was used to record pain , unpleasantness of taste and overall discomfort experienced . Overall , the procedure was associated with minimal pain and discomfort in both groups . There was no significant difference in pain or overall discomfort experienced between the two groups ; however , the sensation of bad taste was significantly worse in the cophenylcaine group . In linear regression , factors that predicted the overall unpleasantness of the experience were primarily pain experienced and secondarily unpleasantness of taste . We conclude that the routine use of cophenylcaine for nasal preparation is not justified before flexible nasendoscopy .
entities: 975
entities: Intervention_Pharmacological
entities: Cophenylcaine
entities: 976
entities: Intervention_Control
entities: placebo
entities: 977
entities: Intervention_Pharmacological
entities: cophenylcaine
entities: 978
entities: Intervention_Control
entities: placebo
entities: 979
entities: Intervention_Pharmacological
entities: cophenylcaine
entities: 980
entities: Intervention_Pharmacological
entities: cophenylcaine
entities: 981
entities: Outcome_Pain
entities: pain , unpleasantness of taste and overall discomfort experienced .
entities: 982
entities: Outcome_Pain
entities: pain and discomfort
entities: 983
entities: Outcome_Pain
entities: pain or overall discomfort
entities: 984
entities: Outcome_Physical
entities: sensation of bad taste
entities: 985
entities: Outcome_Pain
entities: unpleasantness
entities: 986
entities: Outcome_Pain
entities: pain
entities: 987
entities: Outcome_Physical
entities: unpleasantness of taste
entities: 988
entities: Outcome_Adverse-effects
entities: .
entities: 989
entities: Participant_Condition
entities: flexible nasendoscopy :
entities: 990
entities: Participant_Sample-size
entities: 98 patients
entities: 991
entities: Participant_Condition
entities: flexible nasendoscopy .
entities: 992
entities: Participant_Condition
entities: flexible nasendoscopy .