passages: 3951
passages: document
passages: Prevention of spinal anesthesia-induced hypotension in the elderly : comparison between preanesthetic administration of crystalloids , colloids , and no prehydration . The practice of routinely prehydrating patients by infusing a crystalloid or colloid solution ( up to 1.0 L/70 kg ) for prevention of spinal anesthesia-induced hypotension has been challenged recently , after several reports of failure to demonstrate its efficacy in young women . We compared the incidence and frequency of hypotension and vasopressor therapy after spinal anesthesia and no prehydration with crystalloid and colloid prehydration in elderly patients . Eighty-five ASA grade I or II patients ( aged 60-89 yr ) for elective total hip replacement were randomized to receive 500 mL crystalloid solution ( Hartmanns , n = 29 ) , 500 mL colloid ( Haemaccel , n = 28 ) , or no prehydration ( n = 28 ) over 10 min prior to spinal anesthesia . Hypotension was defined as a 30 % decrease from baseline systolic blood pressure ( BP ) or systolic < 90 mm Hg , and was treated with ephedrine 3-mg boluses . Although absolute systolic BP readings were significantly higher in the colloid group between 6 and 30 min ( P < 0.05 ) , the incidence of hypotension was not significantly different between the groups . The incidence of ephedrine use , incidence of nausea/vomiting , and median total dose of ephedrine were similar in all groups . We conclude that , in elderly patients undergoing elective procedures , withholding prehydration is not associated with any greater degree of hypotension or need for vasopressor therapy compared with crystalloid or colloid prehydration .
entities: 3952
entities: Intervention_Pharmacological
entities: crystalloids
entities: 3953
entities: Intervention_Pharmacological
entities: colloids
entities: 3954
entities: Intervention_Control
entities: no prehydration .
entities: 3955
entities: Intervention_Pharmacological
entities: crystalloid
entities: 3956
entities: Intervention_Pharmacological
entities: colloid solution
entities: 3957
entities: Intervention_Control
entities: no prehydration
entities: 3958
entities: Intervention_Pharmacological
entities: crystalloid
entities: 3959
entities: Intervention_Pharmacological
entities: colloid prehydration
entities: 3960
entities: Intervention_Pharmacological
entities: crystalloid solution
entities: 3961
entities: Intervention_Pharmacological
entities: colloid ( Haemaccel
entities: 3962
entities: Intervention_Control
entities: no prehydration
entities: 3963
entities: Intervention_Pharmacological
entities: colloid
entities: 3964
entities: Intervention_Pharmacological
entities: crystalloid
entities: 3965
entities: Intervention_Pharmacological
entities: colloid prehydration .
entities: 3966
entities: Outcome_Physical
entities: incidence and frequency of hypotension and
entities: 3967
entities: Outcome_Other
entities: vasopressor therapy
entities: 3968
entities: Outcome_Physical
entities: Hypotension
entities: 3969
entities: Outcome_Physical
entities: systolic blood pressure
entities: 3970
entities: Outcome_Physical
entities: absolute systolic BP readings
entities: 3971
entities: Outcome_Physical
entities: incidence of hypotension
entities: 3972
entities: Outcome_Other
entities: incidence of ephedrine use
entities: 3973
entities: Outcome_Physical
entities: incidence of nausea/vomiting
entities: 3974
entities: Outcome_Other
entities: median total dose of ephedrine
entities: 3975
entities: Outcome_Physical
entities: hypotension
entities: 3976
entities: Outcome_Other
entities: need for vasopressor therapy
entities: 3977
entities: Participant_Age
entities: the elderly
entities: 3978
entities: Participant_Age
entities: elderly patients
entities: 3979
entities: Participant_Sample-size
entities: Eighty-five
entities: 3980
entities: Participant_Condition
entities: ASA grade I or II patients ( aged 60-89 yr ) for elective total hip replacement
entities: 3981
entities: Participant_Age
entities: elderly patients
entities: 3982
entities: Participant_Condition
entities: undergoing elective procedures