passages: 3371
passages: document
passages: Levobunolol compared with timolol : a four-year study . Fifty-one patients with raised intraocular pressure ( IOP ) were treated for up to four years with one of three ophthalmic solutions : 0.5 % levobunolol , 1 % levobunolol , or 0.5 % timolol . The study was conducted as a double-masked , randomised trial in which medications were administered twice daily to both eyes . Levobunolol and timolol were equally effective in reducing overall mean IOP ; reductions were greater than 8.8 mmHg in all three treatment groups . The study showed levobunolol to be as safe and effective as timolol in the long-term control of raised IOP .
entities: 3372
entities: Intervention_Pharmacological
entities: Levobunolol
entities: 3373
entities: Intervention_Pharmacological
entities: timolol :
entities: 3374
entities: Intervention_Pharmacological
entities: levobunolol
entities: 3375
entities: Intervention_Pharmacological
entities: levobunolol
entities: 3376
entities: Intervention_Pharmacological
entities: timolol .
entities: 3377
entities: Intervention_Pharmacological
entities: Levobunolol
entities: 3378
entities: Intervention_Pharmacological
entities: timolol
entities: 3379
entities: Intervention_Pharmacological
entities: levobunolol
entities: 3380
entities: Intervention_Pharmacological
entities: timolol
entities: 3381
entities: Outcome_Physical
entities: overall mean IOP ;
entities: 3382
entities: Participant_Sample-size
entities: Fifty-one
entities: 3383
entities: Participant_Condition
entities: patients
entities: 3384
entities: Participant_Condition
entities: raised intraocular pressure ( IOP )