passages: 1202
passages: document
passages: [ Clinical study of the efficacy of and tolerance to nimesulide in suppository formulation in pain-inflammatory pathologies of the ear , nose , and throat ] . The efficacy and tolerability of a new pharmaceutical form of the non-steroid anti-inflammatory drug . Nimesulide have been studied in a double blind study compared with flurbiprofen , in 98 patients aged between 18 and 75 suffering from pain-inflammatory pathologies of ENT nature . Both drugs , administered in a dose of one suppository twice a day for 7 days , showed marked anti-inflammatory , analgesic and antipyretic activity and produced a significant , progressive improvement in the typical symptoms of the inflammatory state up to their complete remission . Nimesulide evidenced greater speed and duration of therapeutic action . Assessment on the effectiveness and tolerability as expressed separately by the physician and patient were positive in almost all cases of both treatments .
entities: 1203
entities: Intervention_Pharmacological
entities: nimesulide
entities: 1204
entities: Intervention_Pharmacological
entities: Nimesulide
entities: 1205
entities: Intervention_Pharmacological
entities: flurbiprofen
entities: 1206
entities: Intervention_Pharmacological
entities: Nimesulide
entities: 1207
entities: Outcome_Other
entities: efficacy
entities: 1208
entities: Outcome_Other
entities: tolerance
entities: 1209
entities: Outcome_Other
entities: efficacy
entities: 1210
entities: Outcome_Other
entities: tolerability
entities: 1211
entities: Outcome_Physical
entities: anti-inflammatory , analgesic and antipyretic activity
entities: 1212
entities: Outcome_Physical
entities: symptoms of the inflammatory state
entities: 1213
entities: Outcome_Other
entities: duration
entities: 1214
entities: Outcome_Other
entities: effectiveness
entities: 1215
entities: Outcome_Other
entities: tolerability
entities: 1216
entities: Participant_Sample-size
entities: 98
entities: 1217
entities: Participant_Age
entities: aged between 18 and 75
entities: 1218
entities: Participant_Condition
entities: pain-inflammatory pathologies of ENT nature .