passages: 3822
passages: document
passages: The effects of sevoflurane and isoflurane on recovery from outpatient surgery . This randomized , open-label study compared the investigational inhalational anesthetic sevoflurane with isoflurane in 47 healthy women undergoing elective ambulatory surgery . The women were randomized to receive either sevoflurane or isoflurane in 60 % nitrous oxide-oxygen . Induction with thiopental 3-6 mg/kg was followed by vecuronium 0.1 mg/kg and fentanyl 0-200 micrograms . Duration of anesthesia , time to emergence , orientation , length of stay in the surgical unit , and hospital discharge were recorded . The emergence , length of stay , and discharge times after discontinuation of sevoflurane were 9.7 +/- 0.7 , 120.6 +/- 8.0 , and 244 +/- 15 minutes , respectively , and for isoflurane were 11.9 +/- 1.4 , 106.8 +/- 7.1 , and 282 +/- 24 minutes , respectively ( NS ) . The isoflurane group had a higher frequency of postoperative cough . At the end of surgery , the sevoflurane group received a deeper level of anesthesia ( minimum alveolar concentration 1.5 vs 1.3 ) , however , these patients were oriented earlier ( 13.6 +/- 1.1 min vs 17.0 +/- 1.5 min isoflurane ; p = 0.02 ) after discontinuation of anesthesia , although this difference is of little clinical significance .
entities: 3823
entities: Intervention_Pharmacological
entities: sevoflurane
entities: 3824
entities: Intervention_Pharmacological
entities: isoflurane
entities: 3825
entities: Intervention_Pharmacological
entities: sevoflurane
entities: 3826
entities: Intervention_Pharmacological
entities: isoflurane
entities: 3827
entities: Intervention_Pharmacological
entities: sevoflurane
entities: 3828
entities: Intervention_Pharmacological
entities: isoflurane
entities: 3829
entities: Intervention_Pharmacological
entities: thiopental
entities: 3830
entities: Intervention_Pharmacological
entities: vecuronium
entities: 3831
entities: Intervention_Pharmacological
entities: fentanyl
entities: 3832
entities: Intervention_Pharmacological
entities: sevoflurane
entities: 3833
entities: Intervention_Pharmacological
entities: isoflurane
entities: 3834
entities: Outcome_Physical
entities: Duration of anesthesia
entities: 3835
entities: Outcome_Physical
entities: time to emergence
entities: 3836
entities: Outcome_Physical
entities: orientation
entities: 3837
entities: Outcome_Other
entities: length of stay in the surgical unit
entities: 3838
entities: Outcome_Physical
entities: emergence ,
entities: 3839
entities: Outcome_Other
entities: length of stay
entities: 3840
entities: Outcome_Physical
entities: , and
entities: 3841
entities: Outcome_Other
entities: discharge times
entities: 3842
entities: Outcome_Adverse-effects
entities: postoperative cough
entities: 3843
entities: Outcome_Physical
entities: .
entities: 3844
entities: Outcome_Physical
entities: anesthesia
entities: 3845
entities: Participant_Condition
entities: outpatient surgery .
entities: 3846
entities: Participant_Sample-size
entities: 47
entities: 3847
entities: Participant_Condition
entities: healthy
entities: 3848
entities: Participant_Sex
entities: women
entities: 3849
entities: Participant_Condition
entities: undergoing elective ambulatory surgery
entities: 3850
entities: Participant_Sex
entities: women