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passages: document
passages: [ Neoton and thrombolytic therapy of myocardial infarction ] . AIM To evaluate neoton therapy effects in acute myocardial infarction ( MI ) on systolic function of the left ventricle , arrhythmia and clinical symptoms in patients on thrombolytic therapy ( TLT ) . MATERIAL AND METHODS 106 males with Q-MI entered the study . 47 received treatment without TLT and neoton , 30 patients received TLT with streptokinase preparations , 29 patients were given streptokinase preparations and neoton . Left ventricular systolic function was measured by echocardiography on day 1 , 3 , 7 , 14 , 21 and 28 ; arrhythmia was analysed at Holter monitoring in day 1 and 2 of MI . RESULTS TLT failed to arrest progression of left ventricular dilation by the end of the hospital stay . Patients given neoton in acute period of MI had no increase in the end systolic and diastolic volumes of the left ventricle in the course of the first months after MI onset . Antiarrhythmic action of neoton manifested on MI day 2 . CONCLUSION Neoton given to MI patients receiving TLT prevents progression of left ventricular systolic dysfunction and establishment of predictors of unfavourable outcome .
entities: 503
entities: Intervention_Pharmacological
entities: Neoton
entities: 504
entities: Intervention_Pharmacological
entities: thrombolytic therapy
entities: 505
entities: Intervention_Pharmacological
entities: neoton
entities: 506
entities: Intervention_Pharmacological
entities: thrombolytic therapy ( TLT )
entities: 507
entities: Intervention_Pharmacological
entities: TLT
entities: 508
entities: Intervention_Pharmacological
entities: neoton
entities: 509
entities: Intervention_Pharmacological
entities: TLT
entities: 510
entities: Intervention_Pharmacological
entities: streptokinase
entities: 511
entities: Intervention_Pharmacological
entities: streptokinase preparations
entities: 512
entities: Intervention_Pharmacological
entities: neoton .
entities: 513
entities: Intervention_Pharmacological
entities: neoton
entities: 514
entities: Intervention_Pharmacological
entities: neoton
entities: 515
entities: Intervention_Pharmacological
entities: Neoton
entities: 516
entities: Outcome_Physical
entities: systolic function of the left ventricle , arrhythmia and clinical symptoms
entities: 517
entities: Outcome_Physical
entities: Left ventricular systolic function
entities: 518
entities: Outcome_Physical
entities: arrhythmia
entities: 519
entities: Outcome_Physical
entities: systolic and diastolic volumes
entities: 520
entities: Outcome_Physical
entities: left ventricular systolic dysfunction
entities: 521
entities: Participant_Condition
entities: myocardial infarction
entities: 522
entities: Participant_Condition
entities: patients on thrombolytic therapy ( TLT ) .
entities: 523
entities: Participant_Sample-size
entities: 106
entities: 524
entities: Participant_Sex
entities: males
entities: 525
entities: Participant_Condition
entities: Q-MI