passages: 2316
passages: document
passages: Effect of different rates of infusion of propofol for induction of anaesthesia in elderly patients . The effect of changing the rate of infusion of propofol for induction of anaesthesia was studied in 60 elderly patients . Propofol was administered at 300 , 600 or 1200 ml h-1 until loss of consciousness ( as judged by loss of verbal contact with the patient ) had been achieved . The duration of induction was significantly longer ( P less than 0.001 ) with the slower infusion rates ( 104 , 68 and 51 s ) , but the total dose used was significantly less ( P less than 0.001 ) in these patients ( 1.2 , 1.6 and 2.5 mg kg-1 , respectively ) . The decrease in systolic and diastolic arterial pressure was significantly less in the 300-ml h-1 group at the end of induction and immediately after induction ( P less than 0.01 ) . The incidence of apnoea was also significantly less in the slower infusion group .
entities: 2317
entities: Intervention_Pharmacological
entities: propofol
entities: 2318
entities: Intervention_Pharmacological
entities: propofol
entities: 2319
entities: Intervention_Pharmacological
entities: Propofol
entities: 2320
entities: Outcome_Physical
entities: loss of consciousness
entities: 2321
entities: Outcome_Physical
entities: loss of verbal contact with the patient )
entities: 2322
entities: Outcome_Physical
entities: duration of induction
entities: 2323
entities: Outcome_Physical
entities: systolic and diastolic arterial pressure
entities: 2324
entities: Outcome_Physical
entities: incidence of apnoea
entities: 2325
entities: Participant_Age
entities: elderly patients .
entities: 2326
entities: Participant_Sample-size
entities: 60
entities: 2327
entities: Participant_Age
entities: elderly patients