Yongzhe Jing, Shanji Jin, Ranzhuo Qiao, Jinnü Fang
[Association of adipocytokines with obesity and insulin resistance in Korean-Chinese and Han nationality pupils of Yanbian area]
Wei sheng yan jiu = Journal of hygiene research
shortterm studies reported improved glycemic control decrease ehba1c estimated hemoglobin a1c patients type 1 diabetes covid19 lockdown longterm changes unknown therefore main objectives 1 analyze whether laboratorymeasured hba1c changed two lockdowns 2 investigate potential variables influencing hba1c change cohort study 291 adults type 1 diabetes followed 3 years including prepandemic phase two lockdowns data medical records validated questionnaires assessing health literacy hlseuq16 diabetes selfmanagement dsmqr27 general selfefficacy gse social support fsozuk14 used analyze associations hba1c levels n 2370 performing multivariable linear regressions median age 54 3863 years 159 546 male phases covid19 pandemic associated significant increase laboratorymeasured hba1c levels percent eg first lockdown 023 95 confidence interval ci 007039 p 0005 second lockdown 027 95 ci 015038 p 0001 hba1c change lockdowns significantly affected number checkups 003 95 ci 005 001 p 0010 value hba1c previous observation 033 95 ci 029036 p 0001 educational level secondary versus tertiary 022 95 ci 006038 p 0008 primary versus tertiary 031 95 ci 010052 p 0004 health literacy score point 003 95 ci 005 0002 p 0034 diabetes selfmanagement score point 003 95 ci 004 002 p 0001 use continuous glucose monitoring insulin pump effect hba1c change lockdowns lead worsening glycemic control patients type 1 diabetes particularly patients checkups poor blood glucose values deficits diabetes selfmanagement low health literacy low level education seem greater risk worsening glycemic control lockdowns therefore require special medical care eg telemedicine clinicaltrialsgov identifier nct04821921