Tze Chang Liu
A Case Study of the Adaptive Learning Platform in a Taiwanese Elementary School: Precision Education from Teachers' Perspectives
Education and information technologies
establish evidence activity lack thereof cetuximabbased therapy patients refractory colorectal cancer tumors demonstrate epidermal growth factor receptor egfr expression immunohistochemistry ihcpharmacy computer records reviewed identify patients received cetuximab memorial sloankettering cancer center nonstudy setting first 3 months cetuximabs commercial availability medical records patients reviewed identify colorectal cancer patients experienced failure prior irinotecanbased regimen pathology report indicating egfrnegative tumor ihc pathology slides patients reviewed reference pathologist confirm egfr negativity computed tomography scans cetuximabbased therapy reviewed reference radiologist response rates reported using criteriasixteen chemotherapyrefractory egfrnegative colorectal cancer patients received cetuximab nonstudy setting identified fourteen patients received cetuximab plus irinotecan two received cetuximab monotherapy 16 patients four major objective responses seen response rate 25 95 ci 4 46colorectal cancer patients egfrnegative tumors potential respond cetuximabbased therapies egfr analysis current ihc techniques seem predictive value selection exclusion patients cetuximab therapy basis currently available egfr ihc seem warranted