Maheen Arshad, Angela Trepanier, S Shahrukh Hashmi, Rizwan Naeem, Saqib Mehmood, Myla Ashfaq
Medical students' self-perceived knowledge and clinical comfort with genetics in Pakistan
Journal of genetic counseling
cardiovascular adverse events aes use dipeptidyl peptidase4 dpp4 inhibitors reported suspected since launch dpp4 inhibitors 2006 however studies investigated association cardiovascular aes dpp4 inhibitors objective study detect signals cardiovascular aes use dpp4 inhibitors analyzing korea institute drug safety risk managementkorea adverse event reporting system database kidskd data use oral antidiabetic drugs 2008 2016 extracted kidskd analyzed descriptively data mining conducted calculating three indices proportional reporting ratios reporting odds ratios information components detect signals use oral antidiabetic drugs including dpp4 inhibitors suspected adverse drug reactions adrs confirmed signal detection drug label information korea ministry food drug safety us food drug administration compared cardiovascular aes taking dpp4 inhibitors detected three 10 total 307 ae reports two three cardiovascular aes reported using sitagliptin one using gemiglipitin statistically significant analysis spontaneous adr reports data use dpp4 inhibitors could showed association dpp4 inhibitors cardiovascular aes due small number cardiovascular aes reports