Félix Yllana-Prieto, David González-Gómez, Jin Su Jeong
Influence of two educational Escape Room- Breakout tools in PSTs' affective and cognitive domain in STEM (science and mathematics) courses
Heliyon
rapid development medicine requires regular update clinical data evidence task accomplishment requires participation numerous specialists evidencebased medicine proficient various statistical methods work big data analysis tools biomedical sciences turn requires significant time resources today peak development cognitive systems field medicine special technologies data collection analysis start new trend development cognitive system drug prescription potential analyze automatically information drugs effectiveness safety basis clinical practice experience scientific data according evidence levels patients personal characteristics cognitive system developed use united medical knowledge base umkb umkb semantic network medical knowledge structured according medical ontologies theory fuzzy logic umkb filled simultaneously areas medicine one side filled means linguistic module analyzing medical texts second side academic institutions third side cognitive systems data electronic health records ehrs native language umkb russian designed primarily use russian clinical practice however platform filling knowledge multilingual supports languages means practice world schools may also integrated used umkb peculiarity lies fact umkb presented semantic network biomedical knowledge structured according certain medical ontologies special rules information storage carries data phenomena processes simple complex concepts medicine form interrelated objects keystone underlying umkb model medical knowledge representation able describe area medicine help model one accurately simulate risk factors etiology pathogenesis disease probability time development sequence pathological signs stage disease describing pathological compensatory mechanisms database provides opportunity clarify lot conditions affect mechanism also simple simulate structural functional features concept relationships example compensatory mechanisms reflexes complex anatomical structures features variant anatomy characteristics form reactivity resistance organism important cognitive systems concerning personalized evidencebased medicine describing medical knowledge often situations uncertainty lack sufficiently complete accurate data subject area poorly understood phenomena conflicting theories imprecise concepts semantic network umkb presents complex relationships among medical concepts characterized following features type direction relationship weight value accuracy personalization weight value relationship date actualization multifactorial influence weight value relationship lot elementary intermediate traits influence weight moment actualization supported formalize united medical knowledge base largescale project main goal increase quality duration life personalized care based evidence achieved combining medical big data various fields biomedical sciences basis umkb prototype cognitive system pharmexpert analytical potential developed pharmexpert clinical decision support system drug prescribing integrated medical information system health institutions analyzes electronic health records ehrs format background mode correcting drug therapy according personal patients profile data compatibility drugs system important function selflearning help absorb huge mountain medical data routine clinical practice nearest future works basis data umkb handbooks pharmacology summaries medical products characteristics smpcs available reviews scientific literature clinical guidelines drugs interactions compatibility short term stage clinical testing pharmexpert memorizing cases clinical experience reaction physicians accepting ignoring recommendations system able realize selflearning function rebuilding ties remodeling knowledge semantic network according clinical data generating best standards drug therapy taking account personal characteristics patient levels data evidence working background mode one important advantages system physician asked enter additional data beyond specialist enters ehr everyday basis pharmexpert installed medical information systems range clinical centers russian federation developed prototype cognitive system drug prescription potential analyze automatically information drugs effectiveness safety basis clinical practice experience scientific data according evidence levels patients personal characteristics system based structured semantic network medical knowledge umkb