Jing Yang, Yaqi Zhang, Yin Yuan, Zhongyang Xie, Lanjuan Li
Investigation of the Association between Air Pollution and Non-Alcoholic Fatty Liver Disease in the European Population: A Mendelian Randomization Study
Toxics
backgroundinitial reports severe acute respiratory coronavirus 2 sarscov2 pandemic described children less susceptible coronavirus disease 2019 covid19 adults subsequently severe novel pediatric disorder termed multisystem inflammatory syndrome children misc emerged report unique hematologic immunologic parameters distinguish covid19 misc provide insight pathophysiologymethodswe prospectively enrolled hospitalized patients evidence sarscov2 infection classified misc covid19 patients covid19 classified either minimal severe disease cytokine profiles viral cycle thresholds cts blood smears soluble c5b9 values analyzed clinical dataresultstwenty patients enrolled 9 severe covid19 5 minimal covid19 6 misc five cytokines ifn il10 il6 il8 tnf contributed analysis tnf il10 discriminated patients misc severe covid19 presence burr cells blood smears well cts differentiated patients severe covid19 miscconclusionpediatric patients sarscov2 risk critical illness severe covid19 misc cytokine profiling examination peripheral blood smears may distinguish patients misc severe covid19fundingfinancial support project provided chop frontiers program immune dysregulation team national institute allergy infectious diseases national cancer institute leukemia lymphoma society cookies kids cancer alexs lemonade stand foundation childhood cancer childrens oncology group stand 2 cancer team connor kate amato foundations burroughs wellcome fund cams clinical immunology society american academy allergy asthma immunology institute translational medicine therapeutics