Grace McKeon, Jackie Curtis, Reza Rostami, Monika Sroba, Anna Farello, Rachel Morell, Zachary Steel, Mark Harris, Derrick Silove, Belinda Parmenter, Evan Matthews, Juliana Jamaluddin, Simon Rosenbaum
Co-designing a Physical Activity Service for Refugees and Asylum Seekers Using an Experience-Based Co-design Framework
Journal of immigrant and minority health
avalanche early stage cancer clinical trials coming majority solely use surrogate outcomes validated target outcome interest eg overall survival current hta guidance surrogate outcome validation methodologically practically conducive scenario provide highlevel overview methods approaches conceptual thinking making better use limited evidence within early stage cancer hta submissions outline regulatory hta issues emphasize evidence transitions one another major gaps currently exist may bridged summarize current methodologies practices pros cons outline complementary measurements strengthen evaluations address fallacies biases conventional statistical methods surrogate outcomes validation value realworld data support necessary validity components discussed lastly address importance patient voice better understanding surrogate outcomes may appropriately inform hta conventional surrogate outcome validation represents fraught suboptimal framework hta purposes particularly early stage cancer tools optimizing use limited evidence exist education stakeholders highly needed