Brandon A. Mahal|Chen Mh|Charles L. Bennett|M. W. Kattan|Oliver Sartor|Karen Stein|Anthony V. D’Amico|Paul L. Nguyen
The association between race and treatment regret among men with recurrent prostate cancer
Harvard University|University of Connecticut|MUSC Hollings Cancer Center|Cleveland Clinic|Tulane University|Novartis (United States)|Dana-Farber Brigham Cancer Center|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Dana-Farber Brigham Cancer Center|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute
examine impact race treatment regret among men recurrent prostate cancer surgery radiation prospective comprehensive observational multicenter prostate adenocarcinoma compare registry used study cohort 484 men biochemically recurrent prostate cancer radical prostatectomy external beam radiation brachytherapy multivariable logistic regression used model association race treatment regret determine whether interaction race sexual problems treatment regards treatment regret black men n78 significantly likely treatment regret compared nonblack men n406 218 versus 126 univariable analysis odds ratio 194 95 confidence interval 105356 p003 multivariable analysis black race trended towards longer significantly associated increase treatment regret adjusted aor 184 095358 p0071 interaction race sexual problems treatment pinteraction002 among without sexual problems black men treatment regret nonblack men 267 versus 84 aor 468 1731263 p0002 whereas among sexual problems difference treatment regret black nonblack men 188 versus 173 aor 104 044246 p093 among men recurrent prostate cancer surgery radiation black men nearly twice likely experience treatment regret treating physicians ensure patients fully apprised pros cons treatment options reduce risk subsequent regret