Linia Patel, Carlo La Vecchia, Eva Negri, Silvia Mignozzi, Livia S A Augustin, Fabio Levi, Diego Serraino, Attilio Giacosa, Gianfranco Alicandro
Legume intake and cancer risk in a network of case-control studies
European journal of clinical nutrition
bleeding frequent cause preventable death severe injury coagulopathy associated severe injury complicates control bleeding associated increased morbidity mortality trauma patients causes mechanisms multiple yet clearly definedarticles addressing causes consequences traumaassociated coagulopathy identified reviewed clinical situations various mechanistic causes important sought along quantitative estimates importancecoagulopathy associated traumatic injury result multiple independent interacting mechanisms early coagulopathy driven shock requires thrombin generation tissue injury initiator initiation coagulation occurs activation anticoagulant fibrinolytic pathways acute coagulopathy traumashock altered subsequent events medical therapies particular acidemia hypothermia dilution significant interplay mechanismsthere limited understanding mechanisms tissue trauma shock inflammation initiate trauma coagulopathy acute coagulopathy traumashock considered distinct disseminated intravascular coagulation described conditions rapid diagnosis directed interventions important areas future research