Sharné Naidoo, Nicole Karensa Hoenselaar, Christopher Yelverton
Chiropractic attitude and utilisation of evidence-based practice in South Africa: a secondary analysis
Chiropractic & manual therapies
paradoxical association obesity mortality named obesity paradox inconsistent possibly due difference body mass index bmi central obesity estimated waist circumference wc patterns adiposity enrolled 8513 participants kumamoto intervention conference study multicenter registry included consecutive patients undergoing percutaneous coronary intervention pci 18 centers 2008 2017 japan patients divided quartiles ascending order bmi wc primary endpoints allcause mortality cardiovascular death within year 186 deaths case fatality rate 2211000 personyears followup period lowest group 1st quartile bmi wc worst prognosis among quartiles 1st quartile 42 2nd quartile 19 3rd quartile 15 4th quartile 11 p 0001 2 1st quartile 41 2nd quartile 23 3rd quartile 12 4th quartile 15 p 0001 2 respectively similar results obtained cardiovascular death multivariable analysis adjusted nine conventional factors lowest group 1st quartile bmi hazards ratio 2748 95 confidence interval ci 17124411 wc hazards ratio 2340 95 ci 15253589 independent prognostic factors allcause mortality dividing participants two groups according either bmi wc based national cholesterol education program adult treatment panel iii world health organization classification highest mortality observed lower group however cstatistic adding bmi quartile conventional factors found slightly higher bmi two categories wc two categories 0735 vs 0734 obesity paradox observed patients pci singleuse bmi wc sufficient predict prognosis patients pci