Enrico Ferro|Damian Weikum|Panagiotis Vagenas|Michael Copenhaver|Pedro Gonzáles|Jesús Peinado|Robinson Cabello|Javier R. Lama|Jorge Sánchez|Frederick L. Altice
Alcohol use disorders negatively influence antiretroviral medication adherence among men who have sex with men in Peru
Yale University|Yale University|Yale University|University of Connecticut|Asociación Civil Impacta Salud y Educación|Asociación Civil Impacta Salud y Educación|Asociación Civil Impacta Salud y Educación|Via Libre|Asociación Civil Impacta Salud y Educación|Asociación Civil Impacta Salud y Educación|Yale University
international guidelines increase access antiretroviral therapy art globally art adherence becomes increasingly important achieve hiv treatment prevention tasp goals concentrated hiv epidemic among men sex men msm transgendered women tgw lima peru independent correlates art nonadherence examined inform treatment intervention priorities cross sectional survey hivinfected msm tgw engaged clinical care lima peru june august 2012 302 hivinfected peruvian msmtgw three clinical care sites recruited using convenience sampling participate crosssectional computerassisted adherence survey several standardized screening measures associated art nonadherence examined order determine independent correlates optimal 90 perfect 100 adherence assessed using logistic regression 302 participants recruited 263 871 prescribed art among prescribed art 229 871 reported optimal 146 555 reported perfect adherence prevalence alcohol use disorders aud 432 alcohol dependence 53 recent drug use 60 depression 445 high participants evidence neurocognitive impairment meeting criteria aud depression collinear p 0001 multivariate analysis aud inversely related independent correlate optimal aor 0427 95 ci 01870976 perfect aor 0552 95 ci 03270930 art adherence auds highly prevalent among peruvian hivinfected msm contribute significantly art nonadherence findings support need screening treating underlying auds order meet hiv tasp goals evidencebased strategies targeting auds likely directly improve art adherence indirectly improve overall individual health hiv treatment engagement reduce transmission sexual partners among vulnerable disproportionally affected population