Kimberly D. Mueller|Rebecca L. Koscik|Asenath LaRue|Lindsay R. Clark|Bruce P. Hermann|Sterling C. Johnson|Mark A. Sager
Verbal Fluency and Early Memory Decline: Results from the Wisconsin Registry for Alzheimer's Prevention
University of Wisconsin–Madison|University of Wisconsin–Madison|University of Wisconsin–Madison|University of Wisconsin–Madison|University of Wisconsin–Madison|William S. Middleton Memorial Veterans Hospital|Geriatric Research Education and Clinical Center|University of Wisconsin–Madison|University of Wisconsin–Madison
study examined relationship phonemic semantic category verbal fluency cognitive status wisconsin registry alzheimers prevention wrap longitudinal cohort enriched family history alzheimers disease participants 283 wrap subjects age 53165 years baseline completed three waves assessment 6 years met psychometric criteria either cognitively healthy ch psychometric amnestic mild cognitive impairment amci using approach consider fluency scores ch amci groups differed significantly phonemic total scores category total scores phonemic switching category mean cluster size results suggest measures phonemic semantic fluency yield lower scores persons evidence psychometric amci compared ch differences previously reported group young provide evidence importance including multiple verbal fluency tests targeting preclinical alzheimers disease