Nayu Ikeda, Miwa Yamaguchi, Nobuo Nishi
Trends and Characteristics of Brown Rice Consumption among Adults in Japan: An Analysis of the National Health and Nutrition Surveys, 2012-2019
Nutrients
human papillomavirus hpv vaccine safe effective yet vaccination coverage remains public health objectives many countries examine effectiveness 3component intervention hpv vaccination coverage among adolescents aged 11 14 years 2 months intervention ended component applied alone combination cluster randomized trial incomplete factorial design prevhpv conducted july 1 2021 april 30 2022 french municipalities receiving 0 1 2 3 components intervention randomization stratified school district municipalities socioeconomic level analyses carried 11 14yearold adolescents living participating municipalities regardless implemented prevhpv intervention 3 components 1 educating motivating 11 14yearold adolescents middle schools along parents 2 training general practitioners gps uptodate hpv information motivational interviewing techniques 3 free hpv vaccination school primary outcome hpv vaccination coverage 1 dose 2 months intervention ended among 11 14yearold adolescents living participating municipalities based french national reimbursement database data collected trial groups randomized implement atschool vaccination total 91 municipalities comprising 30 739 adolescents aged 11 14 years 15 876 boys 14 863 girls included analyzed half municipalities 2 lowest socioeconomic quintiles access gps poor twothirds municipalities thirtyeight 61 schools 623 implemented actions 26 45 municipalities 578 least 1 trained gp median vaccination coverage increased 40 percentage points iqr 2073 percentage points 142 percentage points iqr 91173 percentage points 2 months atschool vaccination significantly increased vaccination coverage 550 percentage points 95 ci 313788 percentage points effect observed adolescents education motivation 008 percentage points 95 ci 254 239 percentage points gps training 146 percentage points 95 ci 344 053 percentage points subgroup analyses found significant interaction atschool vaccination access gps higher effect access poor 862 percentage points 95 ci 5371186 percentage points vs 213 percentage points 95 ci 125 550 percentage points p 007 interaction cluster randomized trial within context late covid19 pandemic period limited school gp participation atschool hpv vaccination significantly increased vaccination coverage trial show significant effect training gps education motivation although may observed time elapsed intervention clinicaltrialsgov identifier nct04945655