Arman Jahangiri|Kathleen R. Lamborn|Lewis S. Blevins|Sandeep Kunwar|Manish K. Aghi
Factors associated with delay to pituitary adenoma diagnosis in patients with visual loss
The University of Texas Southwestern Medical Center|University of California, San Francisco|University of California, San Francisco|University of California, San Francisco|University of California, San Francisco
duration visual symptoms associated nonfunctioning pituitary adenoma nfa predictive factor chances visual improvement authors investigated factors associated increased duration visual symptoms patients nfasthe authors retrospectively reviewed nfas resected institution 2004 2010 duration visual symptoms postoperative improvement associated factorsseventyfive patients underwent nfa resection median visual symptom duration 65 months range 1 week15 years multivariate logistic regression showed duration symptoms p 004 age surgery p 02 predicted postoperative normalization vision univariate nonparametric analyses investigating age symptom onset sex race insurance type ophthalmological conditions income marital status emergency department admission language medical provider found age variable significantly prolonging symptom duration p 004 finding confirmed multivariate regression analysis patients 2039 4059 6079 years old median durations symptoms 4 7 9 months respectively seven older patients symptoms attributed preexisting ophthalmological conditions median 18 months nfa diagnosis among age race subgroups largest difference median symptom duration white patients 6079year age range duration 5 months nonwhite patients 6079year age range duration 24 months p 004the authors found older age associated delayed nfa diagnosis visually impaired patients contributing factors attributing visual symptoms nfas ophthalmological conditions patients delayed presentation elderly nonwhite patients findings highlight challenges associated timely nfa diagnosis visually impaired patients key factor chances improvement