Samuel Tekle Mengistu, Oliver Okoth Achila, Simon Tesfay Negash, Yonathan Tesfaldet, Naod Yeibyo Tewolde, Nahom Asmerom Yohannes, Peniel Tsehaye Embaye, Fanus Yemane, Beyene Abraha, Goitom Hagos, Yoseph Tewolde
Portrait of the Emergency Department at Orotta National Referral and Teaching Hospital in Asmara, Eritrea: A Prospective Observational Study
Open access emergency medicine : OAEM
pain common symptom hemophilia may adversely affect patients quality life qol previous post hoc analyses prophylaxis recombinant factor ix fc fusion protein rfixfc published adults adolescents demonstrating improvements healthrelated qol hrqol assessed haemophiliaspecific qol haemaqol questionnaire describe depth evolution qol pain activityrelated domains questions pediatric adolescent adult patients hemophilia b treated rfixfc prophylaxis post hoc analysis data series clinical trials post hoc longterm analysis assessed patientreported outcomes pros kids blong nct01440946 pediatric blong nct01027364 adults adolescents parent studies byond nct01425723 age groups extension study ninetytwo adult adolescent patients started blong study assessed median range duration followup 589 00784 months haemaqol total score significantly reduced baseline 445 p 001 subdomains physical health 910 p 0001 sports leisure 1125 p 001 treatment 269 p 005 view self 581 p 0002 thirty pediatric patients started kids blong study assessed median minmax duration followup 367 90599 months high level satisfaction demonstrated pros baseline maintained rfixfc prophylaxis reduced perceived pain increased levels physical activity sustained longterm improvements qol adult adolescent patients hemophilia b maintained high qol scores pediatric patients