Chun-Chih Lin, Chin-Yen Han, Li-Chin Chen, Ya-Ling Huang, Su-Lun Hwang
Undergraduate nurses' reflections on visual thinking learning to construct inductive reasoning through situated patient pictures: A mixed-method study
Nurse education today
xray phase contrast tomography xpct based wavefield propagation established high resolution threedimensional 3d imaging modality suitable reconstruct intricate structure soft tissues corresponding pathological alterations however biomedical research needed 3d visualisation rendering cytoarchitecture selected cases first throughput needs increased cover statistically relevant number samples second cytoarchitecture quantified terms morphometric parameters independent visual impression third dimensionality reduction classification required identification effects interpretation results address challenges design implement novel integrated high throughput xpct imaging analysis workflow 3d histology pathohistology drug testing approach uses semiautomated data acquisition reconstruction statistical quantification demonstrate capability example lung pathohistology covid19 using small animal model different covid19 drug candidates administered infection tested view restoration physiological cytoarchitecture specifically alveolar morphology end use morphometric parameter determination followed dimensionality reduction classification based optimal transport approach allows efficient discrimination physiological pathological lung structure thereby providing quantitative insights pathological progression partial recovery due drug treatment finally stress xpct image chain implemented used synchrotron radiation validation data used analysis recorded laboratory ct radiation easily accessible preclinical research