Diego Morita|Tracy A. Glauser|Avani C. Modi
Development and validation of the Pediatric Epilepsy Side Effects Questionnaire
Cincinnati Children's Hospital Medical Center|Cincinnati Children's Hospital Medical Center|Cincinnati Children's Hospital Medical Center
develop validate measure antiepileptic drug aed side effects children variety seizure types treatments therapy durationscontent initial 44item measure developed using previously published hague scale expert opinion recognized pediatric epileptologists n 12 caregivers children epilepsy n 21 measure completed caregivers routine clinic visits demographic medical data collected chart reviews factor analysis conducted internal consistency testretest reliability construct validity assessedquestionnaires analyzed 495 children epilepsy mage 101 years range 221 years 42 female 14 african american 32 new onset vs 68 chronic epilepsy final questionnaire pediatric epilepsy side effects questionnaire pesq 19item measure 5 subscales ie cognitive motor behavioral general neurological weight accounts 99 variance internal consistency coefficients testretest reliabilities ranged 072 093 074 097 respectively construct validity demonstrated increasing side effects number drugs increased participants valproic acid significantly higher scores weight scale compared carbamazepinethe pesq reliable valid measure aed side effects children across epilepsy spectrum used clinical research settings