Corey Commins, Margot Bolster, Linda Mulligan
To investigate the pattern of neck injuries and the role of toxicology in cases of hanging and manual/homicidal ligature strangulation in Ireland between 2016 - 2020: A retrospective review and analysis
Journal of forensic and legal medicine
forensic investigative genetic genealogy recent sub discipline forensic genomics leverages high throughput sensitivity detection next generation sequencing established genetic genealogical approaches support identification human remains missing persons investigations investigative lead generation violent crimes facilitate forensic dna evidence analysis forenseq kintelligence multiplex consisting 10230 snps developed design forenseq kintelligence kit miseq fgx sequencing system forenseq universal analysis software described developmental validation accordance swgdam guidelines forensic quality assurance standards using single source samples reported endtoend workflow library preparation data interpretation performance metrics support conclusion genetic information obtained challenging samples compared commercially available forensic targeted dna assays developed capillary electrophoresis ce current next generation sequencing ngs kits due higher number markers overall shorter amplicon sizes 978 150 bp kit design data indicate multiplex robust fit purpose wide range quantity quality samples forenseq kintelligence kit universal analysis software allow transfer genetic component forensic investigative genetic genealogy operational forensic laboratory