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various herbal natural products used multiple purposes medicine due recent interest advancements field alternative medicine past millennia aloe vera used medicine antiinflammatory antibacterial properties proven reduce periodontal disease patients generalised chronic periodontitis study examined impact aloe vera hydrogel conjunction scaling root planing srp sixty patients generalised chronic periodontitis enrolled study split two groups group 1 control srp alone n30 group 2 test aloe vera hydrogel srp n30 clinical parameters related periodontal disease plaque index pi clinical attachment level cal probing depth pd measured baseline three months procedure results compared using statistical product service solutions spss version 230 ibm spss statistics windows armonk ny software pvalue 005 indicated result statistically significant comparing groups thirdmonth periodontal clinical parameters baseline significant improvement p005 third month test group showed better improvement pd cal control group p005 combination srp aloe vera hydrogel greatly improved periodontal clinical parameters however studies longterm followup assessing efficacy modes delivering aloe vera also effect microbiological immunological parameters warranted future substantiate findings