C. Edson Utazi|Julia Thorley|Victor A. Alegana|Matthew J. Ferrari|Saki Takahashi|C. Jessica E. Metcalf|Justin Lessler|Andrew J. Tatem
High resolution age-structured mapping of childhood vaccination coverage in low and middle income countries
University of Southampton|University of Southampton|Flowminder Foundation|University of Southampton|Center for Disease Dynamics, Economics & Policy|Pennsylvania State University|Princeton University|Princeton University|Johns Hopkins University|Flowminder Foundation|University of Southampton
expansion childhood vaccination programs low middle income countries substantial public health success story indicators performance intervention programmes coverage levels numbers covered typically measured national statistics scale large regions due survey design administrative convenience operational limitations mask heterogeneities coldspots low coverage may allow diseases persist even overall coverage high hence decrease inequities accelerate progress towards disease elimination goals finescale variation coverage better characterized using measles example clusterlevel demographic health surveys dhs data used map vaccination coverage 1 km spatial resolution cambodia mozambique nigeria varying agegroup categories children five years using bayesian geostatistical techniques built suite publicly available geospatial covariates implemented via markov chain monte carlo mcmc methods measles vaccination coverage found strongly predicted 45 covariates geostatistical models remoteness consistently selected key variable output 1 1 km maps revealed significant heterogeneities within three countries captured using provincelevel summaries integration population data showed time surveys districts attained 80 coverage one component global vaccine action plan 2020 targets elimination vaccinepreventable diseases requires strong evidence base guide strategies inform efficient use limited resources approaches outlined provide route moving beyond large area summaries vaccination coverage mask epidemiologicallyimportant heterogeneities detailed maps capture subnational vulnerabilities output datasets built open data methods flexible format aggregated operationallyrelevant administrative unit levels