Annette L. Stanton|Joshua F. Wiley|Jennifer L. Krull|Catherine M. Crespi|Constance Hammen|John J. B. Allen|Martha L. Barrón|Alexandra Jorge|Karen L. Weihs
Depressive episodes, symptoms, and trajectories in women recently diagnosed with breast cancer
University of California, Los Angeles|University of California, Los Angeles|University of California, Los Angeles|University of California, Los Angeles|University of Colorado Denver|University of Colorado Cancer Center|University of California, Los Angeles|University of Arizona|University of Arizona|Neurobehavioral Systems|University of California, Los Angeles|University of Arizona
depression carries serious psychosocial physical economic consequences cancer survivors study goals characterize patterns predictors depressive symptoms major depressive episodes recently diagnosed breast cancer patients consecutively recruited women n 460 completed validated interview cidi questionnaire measure cesd depression within 4 months invasive breast cancer diagnosis six additional assessments across 12 months outcomes major depressive episodes continuous symptom scores latent symptom trajectory classes across 12 months 166 women met criteria major depressive episode unemployment predicted depressive episodes correlates controlled distinct trajectory classes apparent estimated 38 women chronically elevated symptoms high trajectory 20 recovered elevated symptoms recovery 43 lower symptoms low low trajectories although 96 episodes occurred high recovery classes 66 women high trajectory episode women low vs high trajectory likely older retired affluent fewer comorbid diseases briefer oncologic treatment women recovery trajectory vs high likely married affluent fewer comorbid diseases assuming available therapeutic resources assessment depressive symptoms episodes several months diagnosis important identification patients risk persistently high depressive symptoms eg younger longer treatment course opens targeted opportunities prevent promote rapid recovery depression