Ning Lou, Xinge Cui, Xinyuan Lin, Ruyun Gao, Chi Xu, Nan Qiao, Ji Jiang, Lu Wang, Weicong Wang, Shanbo Wang, Wei Shen, Xin Zheng, Xiaohong Han
Development and validation of a deep learning-based model to predict response and survival of T790M mutant non-small cell lung cancer patients in early clinical phase trials using electronic medical record and pharmacokinetic data
Translational lung cancer research
studies examined dietary intake changes following weight loss intervention fathers association fatherchild dietary intakes present study aimed evaluate change dietary intake overweight fathers randomised familybased lifestyle intervention healthy dads healthy kids hdhk versus controls ii investigate whether association exists fatherchild dietary intakes secondary analysis conducted fatherchild baseline 3month postintervention data n 93 collected hdhk community randomised controlled trial intentiontotreat linear mixed models used assess dietary changes group time baseline 3month groupbytime interaction cohens used determine effect sizes significant groupbytime effects p 005 favouring fathers intervention group identified total daily energy intake 1956 kj 074 total sugars 45 g 063 sodium 414 mg 058 energy nutrientdense core foods 101 086 fruit 24 071 vegetarian protein sources 12 057 prepacked snacks 17 058 sugarsweetened beverages 41 058 baseline positive correlations observed fatherchild intakes number dietary variables significant correlations observed fatherchild change scores energy carbohydrate r 035 p 0023 energy fruit r 047 p 0002 vegetarian protein sources r 046 p 0002 frequency consuming meals vegetables r 038 p 0012 hdhk intervention successfully improved aspects fathers dietary intakes compared controls fathers eating patterns also correlated children several dietary variables novel data suggest fathers targeted agents dietary change within obesity prevention treatment programmes