Caroline K. Mbuba|Anthony Ngugi|Greg Fegan|Fredrick Ibinda|Simon N. Muchohi|Christopher Nyundo|Rachael Odhiambo|Tansy Edwards|Peter Odermatt|Julie A. Carter|Charles R. Newton
Risk factors associated with the epilepsy treatment gap in Kilifi, Kenya: a cross-sectional study
Kenya Medical Research Institute|Indepth Network|London School of Hygiene & Tropical Medicine|Kenya Medical Research Institute|Kenya Medical Research Institute|Nuffield Orthopaedic Centre|University of Oxford|Kenya Medical Research Institute|Kenya Medical Research Institute|Kenya Medical Research Institute|Kenya Medical Research Institute|London School of Hygiene & Tropical Medicine|University of Basel|Swiss Tropical and Public Health Institute|London International Development Centre|University College London|University of Oxford|Indepth Network|London School of Hygiene & Tropical Medicine|University College London|Kenya Medical Research Institute
many people epilepsy lowincome countries receive appropriate biomedical treatment epilepsy treatment gap might caused patients seeking biomedical treatment adhering prescribed antiepileptic drugs aeds measured prevalence investigated risk factors epilepsy treatment gap rural kenyaall people active convulsive epilepsy identified crosssectional survey 232176 people kilifi approached epilepsy treatment gap defined percentage people active epilepsy accessed biomedical services treatment inadequate treatment information risk factors obtained questionnairebased interview sociodemographic characteristics socioeconomic status access health facilities seizures stigma beliefs attitudes epilepsy factors associated people seeking biomedical treatment adhering aeds investigated separately adjusted age673 people epilepsy interviewed 499 74 reported seeking treatment health facility blood samples taken 502 75 people 132 26 reported taking aeds 189 38 aeds detectable blood sensitivity specificity selfreported adherence compared aeds detected blood 381 95 ci 311454 808 760850 epilepsy treatment gap 624 581666 multivariable analysis failure seek biomedical treatment associated patient holding traditional animistic religious beliefs adjusted odds ratio 185 95 ci 111271 reporting negative attitudes biomedical treatment 086 078095 living 30 km health facilities 389 177851 paying aeds 299 182492 learning difficulties 230 129411 epilepsy longer 10 years 460 2071023 focal seizures 228 150347 reduced adherence associated negative attitudes epilepsy 110 103118 taking aeds longer 5 years 378 179798the sensitivity specificity selfreported adherence poor basis aed detection blood almost twothirds patients epilepsy treatment education epilepsy making aeds freely available health facilities near people epilepsy investigated potential ways reduce epilepsy treatment gapwellcome trust