Ben Rein
Making Science Education More Accessible: A Case Study of TikTok's Utility as a Science Communication Tool
Neuroscience
tenofovirlamivudinedolutegravir tld preferred firstline antiretroviral therapy art regimen additional 50 mg dose dolutegravir tld 50 required rifampincontaining tuberculosis tb cotreatment limited data effectiveness tld 50 individuals tbhiv prospective observational cohort study 12 sites haiti kenya malawi south africa uganda zimbabwe participants starting tld rifampincontaining tb treatment eligible primary outcome hiv1 rna 1000 copiesml end tb treatment enrolled 91 participants tbhiv 75 82 artnave participants starting tld median 15 days tb treatment 10 11 artnave participants starting tld tb treatment 5 5 starting tb treatment median 33 years tld 1 1 starting tb treatment tld changing efavirenzlamivudinetenofovir median age 37 years 35 female median cd4 count 120 cellsmm3 iqr 50295 87 hiv1 rna 1000 copiesml two participants died tb treatment among 89 surviving participants 80 followed tb treatment completion including 7 hiv1 rna result due missed visits primary virologic outcome assessed 73 participants 69 95 95 ci 89100 hiv1 rna 1000 copiesml dolutegravir resistance mutations detected among four participants hiv1 rna 1000 copiesml routine programmatic settings concurrent rifampincontaining tb treatment tld 50 feasible welltolerated achieved high rates viral suppression cohort predominantly artnave people tbhiv