Lena J Lee, Claire J Han, Leorey Saligan, Gwenyth R Wallen
Comparing symptom clusters in cancer survivors by cancer diagnosis: A latent class profile analysis
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
background coronavirus disease 2019 covid19 lead persistent debilitating symptoms referred postacute sequelae sarscov2 infection pasc broad symptomatology lasts months acute infection impacts physical mental health everyday functioning present study aimed evaluate prevalence predictors longterm impairment working ability nonelderly people hospitalised covid19 methods crosssectional study involved 322 subjects hospitalised covid19 1 march 2020 31 december 2022 university hospital bari apulia italy enrolled time hospital discharge followedup median 731 days since hospitalization iqr 466884 subjects reporting comparable working ability reporting impaired working ability compared using mannwhitney test continuous data fishers test chisquare test categorical data multivariable analysis impaired working ability performed using logistic regression model results among 322 subjects interviewed 184 reported comparable working ability 571 134 reported impaired working ability 416 compared precovid19 period multivariable analysis identified age hospital admission 102 95 ci 099 104 female sex 190 95 ci 118 308 diabetes 373 95 ci 157 965 receiving oxygen hospital stay 176 95 ci 101 306 severe disease 051 95 ci 026 101 independent predictors longterm impaired working ability hospitalised covid19 conclusions findings suggest pasc promotes conditions could result decreased working ability unemployment results highlight significant impact syndrome public health global economy need develop clinical pathways guidelines longterm care specific focus working impairment