Xitong Liu, Juanzi Shi, Ben W Mol, Haiyan Bai
Impact of maternal education level on live birth rate after in vitro fertilization in China: a retrospective cohort study
Journal of assisted reproduction and genetics
global programme eliminate lymphatic filariasis lf american samoa conducted seven rounds mass drug administration mda 20002006 world health organization recommends systematic postmda surveillance using transmission assessment surveys tas epidemiological assessment recent lf transmission compared effectiveness two survey designs postmda surveillance schoolbased survey children aged 67 years communitybased survey targeting people aged 8 years 2016 conducted systematic schoolbased tas elementary schools n 29 cluster survey 28 villages two main islands american samoa collected information demographics risk factors infection using electronic questionnaires recorded geolocations schools households blood samples collected test circulating filarial antigen cfa using alere filariasis test strip tested positive prepared slides microscopic examination microfilaria provided treatment descriptive statistics performed questionnaire variables data weighted adjusted account sampling design sex surveys age community survey schoolbased tas n 1143 identified nine antigenpositive children found overall adjusted cfa prevalence 07 95 ci 0318 nine positive children identified one microfilariaemic 7yearold child communitybased survey n 2507 711 households identified 102 antigenpositive people estimated overall adjusted cfa prevalence 62 95 ci 4586 adjusted villagelevel prevalence ranged 0471 cfa prevalence increased age higher males 86 antigenpositive community members slides prepared 22 256 microfilaraemic schoolbased tas limited sensitivity range 0238 negative predictive value range 25833 high specificity range 833100 positive predictive value range 0100 identifying villages ongoing transmission american samoa failed schoolbased tas 2016 communitybased survey identified higher expected numbers antigenpositive people schoolbased tas logistically simpler enabled sampling larger proportion target population results provide good indication overall cfa prevalence older age groups sensitive identifying foci ongoing transmission communitybased survey although operationally challenging identified antigenpositive individuals ages foci high antigen prevalence surveys confirmed recrudescence lf transmission