Man Zhang, Chenglei Su, Xiaoyu Liu, Shuqun Hu, Xianliang Yan
Identification of key molecules in the formation of portal vein tumor thrombus in hepatocellular carcinoma based on single cell transcriptomics and in vitro experiments
Translational cancer research
randomized controlled trial compared efficacy tolerability danzhixiaoyao pills accurate treatment patients burning mouth syndrome bms collect total 78 patients 75 female patients 3 male patients oral mucosa department considered eligible fromoctober 2020 october 2022the patients randomized divided trial group control groupthe trail group received danzhixiaoyao pills mecobalamine tablets control group given mecobalamine tabletsthe visual analogue scale vas beck anxiety inventorybai beck depression inventory bdi oral health impact profile ohip14 traditional chinese medicinetcm syndrome integral adverse reactions performed baseline 2 4 6 weeks treatment descriptive statistics including wilcoxon ranksum test chisquare test median comparisons different times used 1after treatment vas bdiohip14 tcm syndrome integral trial group significant decrease control groupp 005however statistical difference bai scores two groups p 005 2according efficacy determination criteria total effective rate test group 7368 control group 5294 recurrence rate 0 significant difference two groups z2688 p 005 results showed curative effect test group better control group3 adverse effects occurred patients either group danzhixiaoyao pills demonstrated positive effect relieving bms symptoms improving patients overall quality life aes compared control group efficacy evaluation systems verified complementary study provide perfect effective referential evaluation system use chinese patent medicine treatment oral mucosal diseases registry name chinese clinical trail registry registration number chictr2000038189 date registration 20200913 please visit httpswwwchictrorgcnshowprojhtmlproj61462 protocol