Robin S. Chapman|Linda J. Hesketh
Behavioral phenotype of individuals with Down syndrome
University of Wisconsin–Madison|University of Wisconsin–Madison
evidence reviewed developmentallyemerging behavioral phenotype individuals syndrome includes significant delay nonverbal cognitive development accompanied additional specific deficits speech language production auditory shortterm memory infancy childhood fewer adaptive behavior problems individuals cognitive disabilities evidence dementia emerges half individuals studied age 50 research issues affecting control group selection establishing phenotypic characteristics discussed well possible genetic mechanisms underlying variation general cognitive delay specific language impairment adult dementia mrdd research reviews 200068495 wileyliss inc