Willem H Mulder
Probability Distribution of Tree Age for the Simple Birth-Death Process, with Applications to Distributions of Number of Ancestral Lineages and Divergence Times for Pairs of Taxa in a Yule Tree
Bulletin of mathematical biology
longitudinal retrospective image analysis conducted patients diagnosed dry agerelated macular degeneration amd 5 years followup imaging data study aimed investigate relationship ellipsoid zone ez integrity spectral domain optical coherence tomography sdoct visual acuity va using machine learningenabled feature extraction tool quantitative ez parameters derived sdoct images analysis revealed significant correlations ez integrity metrics va eyes excellent va 2025 snellen exhibited higher ez integrity including less ez attenuation thicker ellipsoid zoneretinal pigment epithelium ezrpe thickness higher ez intensity contrast eyes worse va 2040 snellen additionally eyes geographic atrophy ga foveal region displayed compromised ez integrity compared without ga notably baseline ez integrity metrics predictive future va loss findings suggest quantitative sdoct measurements ez integrity could potentially detect early changes dry amd serve valuable indicators predicting future functional outcomes furthermore measurements hold promise use clinical trial screenings offering insights progression disease impact visual acuity study underscores importance ez integrity assessment understanding managing dry amd