Suzanne V. Arnold|Paul S. Chan|Philip G. Jones|Carole Decker|Donna M. Buchanan|Harlan M. Krumholz|P. Michael Ho|John A. Spertus
Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status (TRIUMPH)
Saint Luke's Hospital|Yale University|University of Colorado Health|Yale University|University of Colorado Health|Yale University|University of Colorado Health|Yale University|University of Colorado Health|Yale University|University of Colorado Health|Yale University|University of Colorado Health|Yale University|University of Colorado Health
black patients myocardial infarction mi worse outcomes white patients including higher mortality rates angina worse quality life translational research investigating underlying disparities acute myocardial infarction patients health status triumph study designed examine whether racial differences socioeconomic clinical genetic metabolic biomarker treatment characteristics mediate observed disparities outcomesbetween april 11 2005 december 31 2008 31 567 patients mi prospectively screened 6152 eligible mi 4340 71 enrolled 24 us centers consenting patients detailed chart abstractions medical history processes inpatient care supplemented detailed baseline interview detailed genetic metabolic data obtained hospital discharge 2979 69 3013 patients 69 respectively subset patients blood urine samples obtained 1 month obtained 27 survivors blood samples 6 months obtained 19 survivors centralized followup interviews sought quantify patients postdischarge care outcomes focus health status symptoms function quality life 1 6 12 months 23 27 24 respectively lost followup vital status available 99 patients 12 monthstriumph novel mi registry detailed information patients sociodemographic clinical treatment health status metabolic genetic characteristics wealth patient data collected triumph provide unique opportunities examine factors may mediate racial differences mortality health status mi complex interactions genetic environmental determinants postmi outcomes