A. S. Nanivadekar
The penumbra of randomized control trials
preoccupation randomized control trials basis evidencebased medicine increasingly shadowed study designs last half century include surveys casecontrol studies casecohort studies potential overcome several ethical cost constraints depend embedding research routine practice emphasis relevant limited accurate complete data harnessing information technology purpose epidemiological statistical literacy among clinicians possible nurture network researchoriented practices therapeutic areas given alternative study designs pave way regulatory reforms ultimately benefit discoverers approvers users healthcare tools