Amanda C. Tow|Roee Holtzer|Cuiling Wang|Alok Sharan|Jong Hun Kim|Aharon Z. Gladstein|Yossef Blum|Joe Verghese
Cognitive Reserve and Postoperative Delirium in Older Adults
Albert Einstein College of Medicine|Albert Einstein College of Medicine|Albert Einstein College of Medicine|Albert Einstein College of Medicine|Albert Einstein College of Medicine|Albert Einstein College of Medicine|Albert Einstein College of Medicine|Albert Einstein College of Medicine
objectives examine role cognitive reserve reducing delirium incidence severity older adults undergoing surgery design prospective cohort study setting hospital participants older adults mean age 712 65 women undergoing elective orthopedic surgery n 142 measurements incidence confusion assessment method severity memorial delirium assessment scale postoperative delirium primary outcomes predictors included early literacy latelife cognitive activities proxies cognitive reserve results fortyfive participants 32 developed delirium greater participation cognitive activity associated lower incidence odds ratio 092 corresponding increase 1 activity per week 95 confidence interval ci 086098 p 006 severity b 006 95 ci 011 001 p 02 delirium adjustment age sex medical illnesses baseline cognition greater literacy associated lower delirium incidence severity individual leisure activities reading books using electronic mail singing computer games associated lower dementia incidence severity conclusion greater latelife cognitive reserve associated lower delirium incidence severity older adults undergoing surgery interventions enhance cognitive reserve initiating increasing participation cognitive activities may explored delirium prophylaxis strategy