Edridah M. Tukahebwa|Pascal Magnussen|Henry Madsen|Narcis B. Kabatereine|Fred Nuwaha|Shona Wilson|Birgitte J. Vennervald
A Very High Infection Intensity of Schistosoma mansoni in a Ugandan Lake Victoria Fishing Community Is Required for Association with Highly Prevalent Organ Related Morbidity
Ministry of Health|University of Copenhagen|University of Copenhagen|Ministry of Health|Makerere University|University of Cambridge|University of Copenhagen
schistosomiasis control programmes using mass chemotherapy epidemiological morbidity aspects disease need studied monitor impact treatment make recommendations accordingly aspects examined community musoli village along lake victoria mayuge district highly endemic schistosoma mansoni infectiona cross sectional descriptive study undertaken randomly selected sample 217 females 229 males mean age 26 years sd 16 range 776 years prevalence mansoni 886 95 ci 856915 geometric mean intensity gmi mansoni 2362 95 ci 19854609 eggs per gram epg faeces males significantly higher gmi 3702 epg females 1326 epg age also significantly associated intensity infection levels water contact activities significantly influenced intensity infection highest intensity infection found among people involved fishing however organomegaly significantly associated mansoni except heavy infection 2000 epg liver image patterns c indicative fibrosis found 22 02 respectively mansoni intensity infection associated portal vein dilation abnormal spleen length anaemia observed 364 participants associated mansoni infection intensity considering growth children one morbidity indicators schistosomiasis intensity mansoni significantly associated stuntingalthough organrelated morbidity exception periportal fibrosis mansoni infections highly prevalent two associated individuals high infection intensities results contrast starkly reports ugandan lake albert fishing communities periportal fibrosis prevalent