Prasoon Kumar|Anil Bhansali|M. Ravikiran|Shobhit Bhansali|Pinaki Dutta|JS Thakur|Naresh Sachdeva|Sanjay Kumar Bhadada|Rama Walia
Utility of Glycated Hemoglobin in Diagnosing Type 2 Diabetes Mellitus: A Community-Based Study
Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research|Post Graduate Institute of Medical Education and Research
abstract context although glycated hemoglobin hba1c recently incorporated diagnostic test american diabetes association validity needs established asian indians community setting objective objective study assess validity hba1c screening diagnostic test individuals newly detected diabetes mellitus design setting community based randomized cross sectional study urban chandigarh city north india april 2008 august 2009 subjects subjects included 1972 subjects aged 20 yr older intervention intervention included oral glucose tolerance test glycated hemoglobin subjects main outcome measures utility hba1c diagnostic method newly detected diabetes mellitus subjects evaluated results using world health organization criteria diagnosis diabetes mellitus 134 67 newly detected diabetes mellitus 192 97 known diabetes mellitus 329 166 prediabetes 1317 694 normal 1972 people screened using ada criteria 38 people underdiagnosed hba1c level 61 optimal sensitivity specificity 81 diagnosing diabetes hba1c level 65 2 sd 7 27 sd sensitivity specificity 65 88 42 92 respectively corresponding positive predictive value negative predictive value 752 965 904and 944 respectively diagnosis newly detected diabetes mellitus conclusion hba1c cut point 61 optimal sensitivity specificity 81 used screening test cut point 65 optimal specificity 88 diagnosis diabetes