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routine vaccinations key prevent outbreaks vaccinepreventable diseases however documented declines routine childhood vaccinations us worldwide covid19 pandemic assess covid19 pandemic impacted routine childhood vaccinations evaluating vaccination coverage routine childhood vaccinations children born 20162021 data routine childhood vaccinations reported cdc nine us jurisdictions via immunization information systems iiss december 31 2022 available analyses population size age group obtained national center health statistics bridging population estimates vaccination coverage routine childhood vaccinations age three months five months seven months one year two years calculated vaccine type overall 4313314 series 4 doses dtap 3 doses polio 1 dose mmr 3 doses hib 3 doses hepatitis b 1 dose varicella 4 doses pneumococcal conjugate birth cohort year jurisdiction overall 104 percentage point decrease 4313314 series children born 2020 compared children born 2016 december 31 2022 710 713 children born 2016 2017 respectively date routine childhood vaccinations two years age compared 691 647 606 children born 2018 2019 2020 respectively decline vaccination coverage routine childhood vaccines concerning order protect population health strategic efforts needed health care providers schools parents well state local federal governments work together address declines vaccination coverage covid19 pandemic prevent outbreaks vaccine preventable diseases maintaining high levels population immunity