Ya-Ching Huang, Muna Bhattarai, Emma Cho, Hyunwoo Yoon
The impact of social and emotional support on serious psychological distress among people with functional disabilities and type 2 diabetes
Chronic illness
longterm cardiometabolic consequences late preterm birth 3436 weeks gestation well understood assess whether late preterm birth size gestational age associated cardiometabolic risk cmr childhood retrospective cohort study included 1742 children born ontario canada april 1 2006 september 30 2014 followed september 30 2019 data children enrolled applied research group kids target kids primary care practicebased research network linked administrative health care data ices formerly known institute clinical evaluative sciences participants excluded conditions affecting growth eg failure thrive cystic fibrosis acute chronic conditions asthma highfunctioning autism severe developmental delay families unable communicate english late preterm birth gestational age continuous measure size gestational age primary outcome composite cmr score overall age sexstandardized z score cmr components including waist circumference log triglyceride level glucose level systolic blood pressure highdensity lipoprotein cholesterol level secondary outcomes individual cmr components multivariable linear regression analysis used separately evaluate associations late preterm birth continuous gestational age size gestational age cmr ages 3 12 years among 2440 eligible children 1742 mean sd age 56 22 years 951 boys 546 included final cohort overall 87 children 50 born moderately preterm 34 weeks gestation 145 83 born late preterm 3436 weeks gestation 455 261 born early term 3738 weeks gestation 1055 606 born full term 39 weeks gestation compared children born full term born moderately preterm adjusted 050 95 ci 024075 late preterm adjusted 027 95 ci 006047 higher cmr scores additional gestational week associated 006 u adjusted 95 ci 008 003 u decrease cmr study children born late preterm moderately preterm higher cmr results suggest screening earlylife interventions children may prevent cardiometabolic outcomes