Yunyu Xiao, Kaiwen Bi, Paul Siu-Fai Yip, Julie Cerel, Timothy T Brown, Yifan Peng, Jyotishman Pathak, J John Mann
Decoding Suicide Decedent Profiles and Signs of Suicidal Intent Using Latent Class Analysis
JAMA psychiatry
determining laterality seizure onset zone challenging frontal lobe epilepsy fle due rapid propagation epileptic discharges contralateral hemisphere hemispheric lateralization autonomic control heart rate modulated interactions sympathetic parasympathetic nervous systems based notion laterality seizure foci fle might determined using heart rate variability hrv parameters explored preictal markers differentiating laterality seizure foci fle using hrv parameters twelve patients fle 6 right fle 6 left fle included analyzes total 551 460 left fle 91 right fle 1min epoch electrocardiography data used hrv analysis found hrv parameters differed left right fle groups among machine learning algorithms applied study light gradient boosting machine accurate auc value 0983 classification accuracy 0961 findings suggest hrv parameterbased laterality determination models convenient effective tools clinical settings considering heart rate easily measured real time wearable device proposed method applied closedloop device realtime monitoring tool determining side stimulation