Brynja Ingadóttir, Margrét Hrönn Svavarsdóttir, Corrine Y Jurgens, Christopher S Lee
Self-care trajectories of patients with coronary heart disease: a longitudinal, observational study
European journal of cardiovascular nursing
although frequency noninferiority trials increasing consistency reporting trials vary aim systematic review assess reporting quality radiation therapy noninferiority trials pubmed embase cochrane databases queried randomized controlled radiation therapy trials noninferiority hypotheses published english january 2000 july 2022 performed information scientist descriptive statistics used summarize data 423 records screened 59 14 included fulltext review published 2003 open label common primary cancer type breast n 15 25 altered radiation fractionation n 26 45 radiation deescalation n 11 19 common types interventions common primary endpoints locoregional control n 17 29 progressionfree survival n 14 24 fiftythree 90 reported noninferiority margin 9 17 provided statistical justification margin median absolute noninferiority margin 9 interquartile range 510 median relative margin 151 interquartile range 133204 sample size calculations confidence intervals reported 54 studies 92 intentiontotreat perprotocol analyses reported 27 studies 46 31 trials 53 noninferiority primary endpoint reached variability reporting key components noninferiority trials encourage consideration additional statistical reasoning guidelines previous trials selection noninferiority margin reporting absolute relative margins avoidance statistically vague misleading language reporting future noninferiority trials