Brian W. Pence|Bradley N. Gaynes|Julius Atashili|Julie O’Donnell|Gladys Tayong|Dmitry Kats|Rachel Whetten|Kathryn Whetten|Alfred K. Njamnshi|Peter M. Ndumbe
Validity of an interviewer-administered patient health questionnaire-9 to screen for depression in HIV-infected patients in Cameroon
Duke University|University of North Carolina at Chapel Hill|University of Buea|University of North Carolina at Chapel Hill|Bamenda University of Science and Technology|University of North Carolina at Chapel Hill|Duke Institute for Health Innovation|Duke University|Duke University|Université de Yaoundé I|University of Buea|Université de Yaoundé I
highincome countries depression prevalent hiv patients associated lower medication adherence clinical outcomes emerging evidence lowincome countries supports similar relationships yet little research validated rapid depression screening tools integrated routine hiv clinical careusing qualitative methods adapted patient health questionnaire9 phq9 depression screening instrument use cameroonian patients conducted crosssectional validity study comparing intervieweradministered phq9 reference standard composite international diagnostic interview 400 patients antiretroviral therapy attending regional hiv treatment center bamenda cameroonthe prevalence major depressive disorder mdd past month 3 n11 cases using standard cutoff score 10 positive depression screen phq9 estimated sensitivity 27 95 confidence interval 661 specificity 94 9196 corresponding positive negative likelihood ratios 45 08 little evidence variation specificity gender number hiv symptoms result dementia screenthe low prevalence mdd yielded imprecise sensitivity estimates although phq9 developed selfadministered tool assessed intervieweradministered version due literacy level target populationthe phq9 demonstrated high specificity apparently low sensitivity detecting mdd sample hiv patients cameroon formative work define performance proven screening tools new settings remains important research mental health expands lowincome countries