Hannah Blencowe|Simon Cousens|Mikkel Z. Oestergaard|Doris Chou|Ann?Beth Moller|Rajesh Narwal|Alma J Adler|Claudia Vera Garcia|Sarah Rohde|Lale Say|Joy E Lawn
National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications
London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|World Health Organization|World Health Organization|World Health Organization|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|University of Cape Town|World Health Organization|City of Cape Town
background preterm birth second largest direct cause child deaths children younger 5 years yet data regarding preterm birth 37 completed weeks gestation routinely collected un agencies systematic country estimates time trend analyses done report worldwide regional national estimates preterm birth rates 184 countries 2010 time trends selected countries provide quantitative assessment uncertainty surrounding estimates methods assessed various data sources according prespecified inclusion criteria national registries 563 datapoints 51 countries reproductive health surveys 13 datapoints eight countries studies identified systematic searches unpublished data 162 datapoints 40 countries included 55 countries submitted additional data whos country consultation process 13 countries adequate quality quantity data estimated preterm birth rates using countrylevel loess regression 2010 171 countries two regional multilevel statistical models developed estimate preterm birth rates 2010 estimated time trends 1990 2010 65 countries reliable time trend data 10 000 livebirths per year calculated uncertainty ranges countries findings 2010 estimated 149 million babies uncertainty range 123181 million born preterm 111 livebirths worldwide ranging 5 several european countries 18 african countries 60 preterm babies born south asia subsaharan africa 52 global livebirths occur preterm birth also affects rich countries example usa high rates one ten countries highest numbers preterm births 65 countries estimated time trends three croatia ecuador estonia reduced preterm birth rates 19902010 interpretation burden preterm birth substantial increasing regions reliable data improved recording pregnancy outcomes standard application preterm definitions important recommend addition dataquality indicator per cent live preterm births 28 weeks gestation distinguishing preterm births spontaneous providerinitiated important monitor trends associated increased caesarean sections rapid scale basic interventions could accelerate progress towards millennium development goal 4 child survival beyond funding bill melinda gates foundation grants child health epidemiology reference group cherg save childrens saving newborn lives programme march dimes partnership maternal newborn childe health department reproductive health research