Rachel E. Patzer|Marina Serper|Peter P. Reese|Kamila Przytula|R. Koval|Daniela P. Ladner|Josh Levitsky|Michaël Abécassis|Michael S. Wolf
Medication understanding, non?adherence, and clinical outcomes among adult kidney transplant recipients
Emory University|University of Pennsylvania|University of Pennsylvania|Northwestern University|Emory University|Northwestern University|Northwestern University|Northwestern University|Northwestern University
abstract sought evaluate prevalence medication understanding nonadherence entire drug regimens among kidney transplantation kt recipients examine associations exposures clinical outcomes structured inperson interviews conducted 99 adult kt recipients 2011 2012 two transplant centers chicago il atlanta ga nearly onequarter 24 participants limited literacy measured rapid estimate adult literacy medicine test patients took mean 10 sd 4 medications 32 medication change within last month average patients knew 91 medications selfreport demonstrated proper dosing via observed demonstration 83 medications overall 35 nonadherent based either selfreport tacrolimus level multivariable analyses fewer months since transplant limited literacy associated nonadherence p lt05 patients minority race higher number medications mild cognitive impairment significantly lower treatment knowledge scores nonwhite race lower income associated higher rates hospitalization within year following interview identification factors predispose kt recipients medication misunderstanding nonadherence hospitalization could help target appropriate selfcare interventions