Lutz Kockel, Valentina Zhang, Jenna Wang, Clara Gulick, Madeleine E Laws, Arjun Rajan, Nicole Lantz, Ayla Asgarova, Lillian Dai, Kristian Garcia, Charlene Kim, Michelle Li, Patricio Ordonez-Acosta, Dongshen Peng, Henry Shull, Lauren Tse, Yixang Wang, Wenxin Yu, Zee Zhou, Anne Rankin, Sangbin Park, Seung K Kim
CRISPR/Cas9 gene editing in Drosophila via visual selection in a summer classroom
bioRxiv : the preprint server for biology
hematological cancer patients must comply extensive medical instructions prevent cancer progression relapse psychological comorbidities patient characteristics shown affect compliance however impact posttraumatic stress disorder ptsd adjustment disorder ajd compliance cancer patients remains unclear study aims evaluate compliance hematological cancer patients comprehensively investigate association ptsd ajd symptomatology well sociodemographic medical factors hematological cancer patients crosssectionally assessed via validated questionnaires ptsd pcl5 ajd admn20 three internally developed items compliance medical regimen two referring compliance behavior one item assessing perceived difficulties complying compliance item analyzed descriptively multiple linear regression models tested association compliance ptsd ajd symptomatology sociodemographic medical factors total 291 patients included response rate 58 nine ten patients reported either never 67 rarely 25 change medical regimen however 8 reported change often compliance behavior mostly rated easy 36 easy 45 implement nevertheless 19 perceived partly difficult difficult follow medical regimen symptoms ajd 031 p 0001 associated difficulties comply higher compliance behavior turn associated stem cell transplantation sct treatment 021 p 0001 lower education 019 p 0002 although patients indicated comply medical regimen considerable subgroup patients indicated subjectively perceived difficulties thus seem require additional support implementing medical instructions possibly improved medical communication patient health literacy shared decisionmaking