Christopher D. Miller|Lawrence Phillips|David C. Ziemer|Daniel L. Gallina|Curtiss B. Cook|Imad M. El?Kebbi
Hypoglycemia in Patients With Type 2 Diabetes Mellitus
Emory University|Emory University|Emory University|Emory University|Endocrinology Research Center|Emory University
although hypoglycemia common complication intensive diabetes therapy little information risk factors hypoglycemia patients type 2 diabetes mellitusto determine prevalence predisposing factors hypoglycemia patients type 2 diabetesretrospective crosssectional analysis set outpatient specialty diabetes clinic included patients baseline followup visits april 1 october 31 1999 hypoglycemia defined typical symptoms relieved eating andor blood glucose level less 60 mgdl 33 mmoll univariate multivariate logistic regression used determine contributions hypoglycemia age sex diabetes duration body mass index calculated weight kilograms divided square height meters fasting plasma glucose level glycosylated hemoglobin hba1c level type therapy previous episodes followup visitwe studied 1055 patients prevalence hypoglycemic symptoms 12 976 patients treated diet alone 16 56346 using oral agents alone 30 193633 using insulin p001 severe hypoglycemia occurred 5 patients 05 using insulin multiple logistic regression analysis demonstrated insulin therapy lower hba1c level followup younger age report hypoglycemia baseline visit independently associated increased prevalence hypoglycemia significant predictors severe hypoglycemiamild hypoglycemia common patients type 2 diabetes undergoing aggressive diabetes management severe hypoglycemia rare concerns hypoglycemia deter efforts achieve tight glycemic control patients type 2 diabetes