Kyong-Jee Kim, Changwon Kee
Evaluation of an e-PBL model to promote individual reasoning
Medical teacher
wasaimed herein investigate coronavirus disease covid19 cancer patients compare hematological solid organ cancer patients terms course outcome disease data cancer patients laboratoryconfirmed covid19 infection analyzed retrospectively risk factors poor prognosis effect vaccination clinical outcomes patients evaluated total 403 cancer patients diagnosed covid19 march 1st 2021 november 30th 2022 included 329 816 solid 74 184 hematological cancers hospitalization intensive care unit icu admission rates significantly higher hematological cancer patients compared solid organ cancer patients 730 vs 359 p 0001 257 vs 140 p 0013 respectively covid19related case fatality rate cfr defined 154 higher hematologicalcancer patientsthan inthe solid organ cancer patients 230 vs 137 p 0045 higher patients metastaticadvanced disease compared cancer stages p 0001 solid organ cancergroup hospitalization icu admission covid19 cfr higher patients respiratory genitourinary cancers p 0001 total 288 718 patients receivedcovid19 vaccination 164 5694 had2 doses 124 4306 had3 doses hospitalization rate higher patients 2 doses vaccine compared 3 doses 482 vs 298p 0002 patients covid19related death higher levels leucocyte neutrophil ddimer troponin creactive protein crp procalcitonin ferritin lower levels lymphocyte survivors logistic regression analysisthe risk covid19related mortality higher hematological cancer patientsor1726 male or1757 predeltadelta variants or1817 study revealed increased risk covid19related serious events hospitalization icu admission death patients hematological cancerscompared solid organ cancers wasalso shown receiving 3 doses covid19 vaccine protective severe illness need hospitalization 2 doses