Kristine Yaffe|Cherie Falvey|Tamara B. Harris|Anne B. Newman|Suzanne Satterfield|Arie M. C. A. Koster|Hilsa N. Ayonayon|Eleanor M. Simonsick
Effect of socioeconomic disparities on incidence of dementia among biracial older adults: prospective study
University of California, San Francisco|University of California, San Francisco|National Institute on Aging|University of Pittsburgh|University of Tennessee Health Science Center|Maastricht University|Berry (United States)|MedStar Harbor Hospital
examine whether observed differences dementia rates black white older people living community could explained measures socioeconomic status income financial adequacy education literacy health related factorsprospective cohort studygeneral community two clinic sites united states pittsburgh pennsylvania memphis tennessee2457 older people mean age 736 years 1019 415 black 1233 502 women dementiafree baseline health aging body composition studydementia determined 12 years ending january 2011 prescribed dementia drugs hospital records decline global cognitive scores influence socioeconomic status health related factors dementia rates examined series cox proportional hazard models variables added sequentially covariate blocksover followup 449 183 participants developed dementia black participants likely white participants develop dementia 211 207 v 238 166 p0001 unadjusted hazard ratio 144 95 confidence interval 120 174 hazard ratio lessened somewhat adjustment demographics apolipoprotein e e4 comorbidities lifestyle factors 137 112 167 greatly reduced longer statistically significant socioeconomic status added 109 087 137these findings suggest differences burden risk factors especially socioeconomic status may contribute higher rates dementia seen among black compared white older people strategies aimed reducing disparities may favorably affect incidence dementia