Su Jin Jeong|Dong Wook Shin|Ji Eun Lee|Jung Hyeon Hyeon|Jinkook Lee|SangYun Kim
Anemia is associated with incidence of dementia: a national health screening study in Korea involving 37,900 persons
Seoul National University Hospital|Samsung Medical Center|Seoul National University Hospital|Seoul National University Hospital|University of Southern California|Seoul National University Bundang Hospital
aim study investigate whether anemia associated dementia incidence elderlyusing korean national health insurance servicenational health screening cohort nhisheals database identified 66yearold subjects n 37900 free dementia stroke anemia hemoglobin 12 gdl women 13 gdl men severity anemia mild moderate severe defined using world health organization criteria incidence dementia identified using international classification diseases tenth revision dementia diagnosis codes f00 f01 f02 f03 g30 prescription antidementia drug cox proportional hazards regression models used assess hrs dementia incidence according anemiaafter adjusting sex baseline cognitive state body mass index smoking status household income disability depression hypertension diabetes dyslipidemia found significant association anemia dementia incidence adjusted hr 124 95 ci 102151 adjusted hrs incidence dementia according severity anemia 119 95 ci 098145 mild anemia 147 95 ci 097221 moderate anemia 572 95 ci 1841781 severe anemia showing significant p value trend p 0003anemia independent risk factor dementia incidence marked increase risk associated severe anemia