Noel T. Brewer|Alice R. Richman|Joseph DeFrank|Valerie F. Reyna|Lisa A. Carey
Improving communication of breast cancer recurrence risk
University of North Carolina at Chapel Hill|East Carolina University|University of North Carolina at Chapel Hill|Decision Research|Cornell University|University of North Carolina at Chapel Hill
doctors commonly use genomic testing breast cancer recurrence risk sought assess whether standard genomic report provided doctors good approach communicating results patients 20092010 interviewed 133 patients stages ii nodenegative hormone receptorpositive breast cancer eligible oncotype dx genomic test randomized experiment patients viewed six vignettes presented hypothetical recurrence risk test results vignette described low intermediate high chance breast cancer recurrence 10 years vignettes used one five risk formats increasing complexity derived standard report accompanies commercial assay sixth format used icon array among women received genomic recurrence risk test 63 said doctors showed standard report standard report format yielded among errors identification whether result low intermediate high risk ie gist results whereas newly developed risk continuum format yielded fewest errors 17 vs 5 023 95 ci 010052 high recurrence risk results presented standard format women made errors 35 time women rated standard report one least understandable leastliked formats rated risk continuum format among understandable liked results differed little health literacy numeracy prior receipt genomic test results clinical care actual genomic test results standard genomic recurrence risk report difficult women understand interpret formats less complex report potentially including risk continuum format would effective communicating test results patients