Shobha Ghosh|Roy A. Pleasants|Jill A. Ohar|James F. Donohue|M. Bradley Drummond
&lt;p&gt;Prevalence and factors associated with suboptimal peak inspiratory flow rates in COPD&lt;/p&gt;
University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill
adequate peak inspiratory flow rate pifr required drug dispersion dry powder inhalers dpis prevalence pifr discordance suboptimal pifr prescribed inhalers factors influencing devicespecific pifr unclear copd objective study determine prevalence pifr discordance associated clinical factors stable copd populationan observational singlecenter cohort study conducted including 66 outpatients copd pifr measured using incheck dial applied resistance prescribed inhalers participants defined discordant measured pifr 30 lmin 60 lmin high lowmedium resistance devices respectively using inspiratory effort participant normally used prescribed dpithe median age copd participants 694 years 92 white 47 female total 48 using lowmedium resistance dpis diskusellipta 76 used highresistance dpi handihaler total 40 copd participants discordant prescribed inhalers female gender factor consistently associated lower pifr shorter height associated reduced pifr lowmedium resistance r044 p001 high resistance r020 p016 correlation pifr incheck dial pifr measured standard spirometerpifr reduced stable copd patients female gender factor consistently associated reduced pifr discordance prescribed inhalers seen 40 copd patients suggesting many copd patients generate adequate inspiratory force overcome prescribed dpis resistance course normal use