Claire J Han, Fode Tounkara, Matthew F Kalady, Anne M Noonan, Electra D Paskett, Diane Von Ah
Racial/Ethnic Disparities in HRQoL and Associated Risk Factors in Colorectal Cancer Survivors: With a Focus on Social Determinants of Health (SDOH)
Journal of gastrointestinal cancer
stereology collection methods makes possible produce interpretations actual threedimensional features objects based data obtained twodimensional sections images quantitative morphological studies central nervous system undergone significant development particular new approaches known designbased methods successfully applied neuromorphological research morphology macroscopic microscopic structures numbers cells organs structures geometrical features length volume surface area volume components organ concerned estimated unbiased manner using stereological techniques practical simplest stereological method fractionator technique one widely used methods total particle number estimation review summarizes fractionator methods theory practice important feature methods simplicity application underlying reasoning although three different types fractionator method physical optical isotropic biochemical logic underlying applications remains fractionator method one strongest best options among available methods estimation total number cells given structure organ second part review focuses recent developments stereology including deal lost caps tissue section deformation shrinkage discusses issues calibration particle identification role stereology era nonhistological alternative counting cells isotropic fractionator brain soup technique