Ayesha De Costa|Anita Shet|Nagalingeswaran Kumarasamy|Per Ashorn|Bo Eriksson|Lennart Bogg|Vinod Diwan
Design of a randomized trial to evaluate the influence of mobile phone reminders on adherence to first line antiretroviral treatment in South India - the HIVIND study protocol
St. John's National Academy of Health Sciences|Karolinska Institutet|St. John's National Academy of Health Sciences|Karolinska Institutet|YR Gaitonde Centre for AIDS Research and Education|Tampere University|Karolinska Institutet|Karolinska Institutet|Karolinska Institutet
poor adherence antiretroviral treatment public health challenge associated treatment hiv although different adherencesupporting interventions reported long term feasibility low income settings remains uncertain thus need explore sustainable contextual adherence aids settings test using rigorous scientific designs current ubiquity mobile phones many resourceconstrained settings make contextually appropriate relatively low cost means supporting adherence india mobile phones wide usage acceptability potentially feasible tools enhancing adherence medications paper presents study protocol trial evaluate influence mobile phone reminders adherence firstline antiretroviral treatment south india600 treatment nave patients eligible firstline treatment per national antiretroviral treatment guidelines recruited trial two clinics south india patients randomized control intervention arms control arm receive standard care intervention arm receive standard care plus mobile phone reminders reminder take form automated call picture message reminders delivered week time chosen patient patients followed 24 months till primary outcome ie virological failure reached whichever earlier selfreported adherence secondary outcome analysis intentiontotreat costeffectiveness study intervention also carried outstepping telecommunications technology resourcelimited healthcare settings priority world health organization trial evaluate use mobile phone reminders influence adherence firstline antiretrovirals indian context