David A Birch, Susan Goekler, M Elaine Auld, David K Lohrmann, Adrian Lyde
Quality Assurance in Teaching K-12 Health Education: Paving a New Path Forward
Health promotion practice
examine role total mesorectal excision management rectal cancera prospective consecutive case seriesa district hospital referral center basingstoke englandfive hundred nineteen surgical patients adenocarcinoma rectum treated cure palliationanterior resections n 465 low stapled anastomoses 407 total mesorectal excisions abdominoperineal resections n 37 hartmann resections n 10 local excisions n 4 laparotomy n 3 preoperative radiotherapy used 49 patients 7 abdominoperineal resections 38 anterior resections 3 hartmann resections 1 laparotomylocal recurrence cancerspecific survivalcancerspecific survival surgically treated patients 68 5 years 66 10 years local recurrence rate 6 95 confidence interval 210 5 years 8 95 confidence interval 214 10 years 405 curative resections local recurrence rate 3 95 confidence interval 05 5 years 4 95 confidence interval 08 10 years diseasefree survival group 80 5 years 78 10 years analysis histopathological risk factors recurrence indicates dukes stage extramural vascular invasion tumor differentiation variables resultsrectal cancer cured surgical therapy alone 2 3 patients undergoing surgical excision stages 4 5 patients curative resections future clinical trials adjuvant chemotherapy radiotherapy strategies incorporate total mesorectal excision surgical procedure choice