Salma Patel|Chad Cherington|Robyn M. Scherber|Kathryn Barr|Ryan McLemore|Donald E. Morisky|Stephen Cha|Farouk Mookadam|Fadi Shamoun
Assessment of Patient Adherence to Direct Oral Anticoagulant vs Warfarin Therapy
direct oral anticoagulants doacs may effective times safer warfarin doacs require regular serum level monitoring patients interaction health care system may reduced authors knowledge although studies evaluated warfarin adherence studies evaluated realworld adherence doacsto evaluate whether difference exists medication adherence patients taking doacs vs patients taking warfarinthe electronic medical records anticoagulation clinic database mayo clinic scottsdale arizona reviewed inclusion criteria adults taking doacs matching cohort taking warfarin january 1 2011 december 30 2013 morisky medication adherence scale8 item validated medication adherence tool used evaluate adherence cohorts qualitative covariates analyzed using ordinal logistic regressionof 324 surveys sent 110 patients 340 responded patients took doacs atrial fibrillation took doacs venous thromboembolism overall 60 66 patients 909 doac group 42 44 patients 955 warfarin group reported medium high adherence difference adherence scores 2 groups statistically significant p8similar adherence noted doacs warfarin regardless frequency serum level monitoring