Kathleen Ell|Brenda Quon|David I. Quinn|Megan Dwight?Johnson|Anjanette Wells|Pey Jiuan Lee|Bin Xie
Improving treatment of depression among low-income patients with cancer: the design of the ADAPt-C study
University of Southern California
article describes randomized clinical trial methodology populationbased study oncology patients receiving cancer care public sector medical center primary goal test effectiveness socioculturally tailored collaborative care intervention improving depression quality life outcomes among lowincome ethnic minority patients major depression cancerthe patient health questionnaire phq9 depression scale used identify patients meeting criteria major depression one cardinal depression symptom plus phq9 score 10 studyeligible patients 90 days cancer diagnosis receiving acute cancer treatment followup care oncology clinics patients advanced disease limiting life expectancy 6 months acutely suicidal antipsychotic medication excluded allowing attrition due death loss followup study powered 80 level detect 20 difference study arms proportion patients 50 reduction phq9 symptoms 12 monthsof 2330 patients screened 232 met criteria 824 enrollment rate resulted 446 primarily women recruited randomized intervention usual carethe study applies methods used primary care depression trials adaptations oncology care clinics lowincome minority patients