Pranali Khobragade|Emma Nichols|Erik Meijer|Mathew Varghese|Joyita Banerjee|Aparajit Ballav Dey|Jinkook Lee|Alden L. Gross|Mary Ganguli
Performance of the Informant Questionnaire on Cognitive Decline for the Elderly (IQCODE) in a nationally representative study in India: the LASI-DAD study
University of Southern California|Johns Hopkins University|University of Southern California|Institute of Mental Health|All India Institute of Medical Sciences|All India Institute of Medical Sciences|University of Southern California|Johns Hopkins University|University of Pittsburgh
abstract background low middleincome countries like india anticipate rapid population aging increases dementia burden india dementia screening scales originally developed contexts need assessed feasibility validity given number different languages varying levels literacy education method using data longitudinal aging study indiadiagnostic assessment dementia n 4028 characterize performance informant questionnaire cognitive decline elderly iqcode described patterns correlates missingness evaluated psychometric properties scale assessed criterion validity hindi mental state examination hmse using linear regression results several iqcode items high levels missingness associated urbanicity respondents gender informants generation vs younger generation full iqcode scores showed strong criterion validity hmse 1point increase iqcode score associated 303point lower score hmse controlling age gender urbanicity statistically significant association iqcode hmse stronger urban rural settings pvalue interaction 004 associations iqcode hmse remained unchanged removing three items highest levels differential missingness remembering addresses telephone numbers ability work familiar machines ability learn use new gadget machine conclusion findings raise questions value including items high proportions missingness may signal cultural irrelevance removing affect criterion validity