Leodoro J Labrague, Sulaiman Al Sabei, Omar Al Rawajfah, Ikram Ali Burney, Raeda Abu AlRub
Factors associated with millennial nurses' intention to pursue formal leadership roles: a cross-sectional study
Leadership in health services (Bradford, England)
objective medical imaging offered noninvasive window visualize tumors radiomics transforming images quantitative data tumor phenotyping however intricate web linking imaging features clinical endpoints tumor biology mostly uncharted study aimed unravel connections ct imaging features clinical characteristics including tumor histopathological grading clinical stage endocrine symptoms alongside immunohistochemical markers tumor cell growth ki67 index nuclear mitosis ratexdapproach conducted retrospective analysis data 137 patients pancreatic neuroendocrine tumors undergone contrastenhanced ct scans across two institutions study focused three clinical factors pathological grade clinical stage endocrine symptom status addition two immunohistochemical markers ki67 index rate nuclear mitosis computed predefined 2d 3d learningbased features via sparse autoencoder sae scans unearth relationships imaging features clinical factors immunohistochemical markers employed spearman rank correlation along benjaminihochberg method furthermore developed validated radiomics signatures foresee clinical factorsxdmain results 3d imaging features showed strongest relationships clinical factors immunohistochemical markers association pathological grade mean absolute value correlation coefficient cc 2d sae 3d features 0331801196 0214900361 0418900882 respectively association ki67 index rate nuclear mitosis 3d features also showed higher correlations cc 0405300786 0406100806 addition 3d featurebased signatures showed optimal performance clinical factor predictionxdsignificance found relationships imaging features clinical factors immunohistochemical markers 3d features showed higher relationships clinical factors immunohistochemical markers