Jiahao Zhu, Houpu Liu, Rui Gao, Lilu Ding, Jing Wang, Ye Yang, Dan Zhou, Yingjun Li
Understanding the educational inequalities in suicide attempts and their mediators: a Mendelian randomisation study
General psychiatry
biological motion imparts rich information related movement actions intentions affective state others provide foundational support various aspects social cognition behavior given atypical social communication cognition hallmark symptoms autism spectrum disorder asd many theorized potential source deficit may lie dysfunctional neural mechanisms biological motion processing synthesis existing literature provides support biological motion processing deficits autism spectrum disorder although high study heterogeneity inconsistent findings complicate interpretation attempted reconcile residual controversy investigating possible modulating role attention biological motion processing asd employed highdensity electroencephalographic recordings participants observed pointlight displays upright inverted scrambled biological motion two task conditions explore spatiotemporal dynamics intentional unintentional biological motion processing children adolescents asd n 27 comparing control cohort neurotypical nt participants n 35 behaviorally asd participants able discriminate biological motion similar accuracy nt controls however electrophysiologic investigation revealed reduced automatic selective processing upright biologic versus scrambled motion stimuli asd relative nt individuals ameliorated task demands required explicit attention biological motion additionally observed distinctive patterns covariance visual potentials evoked biological motion functional social ability vineland adaptive behavior scalesocialization domain scores differentially associated biological motion processing n1 period asd nt group crosssectional design study allow us definitively answer question whether developmental differences attention biological motion cause disruption social communication sample limited children average cognitive ability together data suggest individuals asd able discriminate explicit attention biological nonbiological motion demonstrate diminished automatic neural specificity biological motion processing may cascading implications development higherorder social cognition