Guy G. Potter|Brenda L. Plassman|James R. Burke|Mohammed U. Kabeto|Kenneth M. Langa|David J. Llewellyn|Mary A.M. Rogers|David C. Steffens
Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites
Duke University Hospital|Duke Medical Center|Duke University Hospital|Duke Medical Center|Duke University Hospital|Duke Medical Center|University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|VA Center for Clinical Management Research|University of Cambridge|University of Michigan–Ann Arbor|Duke University Hospital|Duke Medical Center
background diagnosis cognitive impairment dementia must reflect increasingly diverse aging united states population study compared direct testing informant reports cognition clinical diagnoses cognitive impairment dementia african americans whites methods participants aging demographics memory study completed inperson dementia evaluations assigned clinical diagnoses consensus panel dementia experts normal cognitive impairment demented cind dementia consortium establish registry alzheimers disease cerad total score informant questionnaire cognitive decline elderly iqcode used assess cognitive performance reported cognitive decline results higher cerad total score associated lower odds cind dementia comparable ratios african americans whites higher iqcode scores associated increased odds dementia african americans whites higher iqcode scores associated increased odds cind among whites among african americans conclusions cultural differences may influence informant reports prevalent cind dementia findings also highlight need comparative research establish cultural validity measures used diagnose conditions