Sunil Nath
Elucidating Events within the Black Box of Enzyme Catalysis in Energy Metabolism: Insights into the Molecular Mechanism of ATP Hydrolysis by F1-ATPase
Biomolecules
physical cognitive function indicators aging characterized loss adaptive response life challenges functional limitations subsequently affecting quality life study aimed identify direct effect physical function indirect effect cognitive function quality life older adults mild cognitive impairment study participants 79 older adults recruited community centers four urban districts korea participants completed selfreported questionnaire demographic characteristics outcome variables outcome measures included physical function grip strength balance mobility cognitive function mental physical components quality life qol statistical analyses conducted using hierarchical multiple linear regression process macro mediation analysis mean age participants 7746 years old elementary lower education level 532 mean score cognitive function 1639 sd 65 physical function grip strength balance mobility cognitive function explained 25 variance physical p 0004 29 mental p 0001 components qol controlling age sex education level mobility associated physical 027 p 0024 mental 036 p 0002 components qol cognitive function partially mediated relationship balance physical component qol proportion mediation 55 conclusion physical cognitive function significant predictors qol older adults cognitive impairment specifically balance significant indirect effects physical component qol cognitive function mediator healthpromoting strategies could effective focusing direct effect physical function well mediating effect cognitive function promote quality life population