Kabiru Olusegun Akinyemi|Akeeb O. Bola Oyefolu|Wasiu Bamidele Mutiu|BA Iwalokun|Edward Sunday Ayeni|Samuel Oluwasegun Ajose|Stephen Obaro
Typhoid Fever: Tracking the Trend in Nigeria
Lagos State University|Lagos State University|Lagos State University|Nigerian Institute of Medical Research|Lagos State University Teaching Hospital|Lagos State University|University of Nebraska Medical Center
typhoid fever continues pose serious health challenge developing countries reliable database positive blood cultures essential prompt interventions generate reliable data salmonella enterica serovar typhi typhipositive blood culture trends typhoidal salmonella nigeria alongside changing contextual factors antimicrobial resistance patterns retrospective cohort study conducted two hospitals lagos 1993 2015 medical records typhoid patients reviewed positive culture antibiogram using standard procedures analyzed additional data retrieved previous study seven facilities abuja three hospitals kano 2008 2017 2013 2017 respectively declining trend percent positivity typhi observed abuja erratic trends lagos kano lagos 80 isolates entire study period exhibited multiple drug resistance generally increasing trend chosen contextual factors improvements recorded female literacy access improved water supply diarrheal mortality children younger 5 years gross domestic product poverty access improved sanitation facilities decreased time nationally typhoid fever still poses serious health challenge nigeria antibiotic resistance major health security issue combined approach includes use typhoid vaccines improvements sanitation safe water supply essential