David C Hollock, Nicholas J Brunsink, Austin B Whittaker, Andrew Lawson, Toni B Pence, Brittany Morago, Elham Ebrahimi, James Stocker, Amelia Moody, Amy Taylor, Beatriz Sousa Santos, Alejandra J Magana
Virtual Access to STEM Careers: In the Field Experiments
IEEE computer graphics and applications
purpose drug repurposing leverage previously approved drugs particular disease indication apply another disease seen faster costeffective approach drug discovery powerful tool achieving precision medicine addition drug repurposing used identify therapeutic candidates rare diseases phenotypic conditions limited information disease biology machine learning artificial intelligence ai methodologies enabled construction effective datadriven repurposing pipelines integrating analyzing largescale biomedical data recent technological advances especially heterogeneous network mining natural language processing opened exciting new opportunities analytical strategies drug repurposing review first introduce challenges repurposing approaches highlight success stories including covid19 pandemic next review existing computational frameworks literature organized basis type biomedical input data analyzed computational algorithms involved conclusion outline exciting new directions drug repurposing research may take pioneered generative ai revolution