Stefanie A Busgang, Syam S Andra, Paul Curtin, Elena Colicino, Matthew J Mazzella, Moira Bixby, Alison P Sanders, John D Meeker, Marissa Hauptman, Shirisha Yelamanchili, Wanda Phipatanakul, Chris Gennings
A cross-validation based approach for estimating specific gravity in elementary-school aged children using a nonlinear model
Environmental research
reproductive development alligators contaminated control lake central florida examined lake apopka adjacent epa superfund site listed due extensive spill dicofol ddt metabolites compounds act estrogens contaminants lake also derived extensive agricultural activities around lake continue today sewage treatment facility associated city winter garden florida examined hypothesis estrogenic contaminant caused current failure recruitment alligators lake apopka supporting data include following 6 months age female alligators lake apopka plasma estradiol17 beta concentrations almost two times greater normal females control lake lake woodruff apopka females exhibited abnormal ovarian morphology large numbers polyovular follicles polynuclear oocytes male juvenile alligators significantly depressed plasma testosterone concentrations comparable levels observed normal lake woodruff females three times lower normal lake woodruff males additionally males lake apopka poorly organized testes abnormally small phalli differences lakes sexes plasma hormone concentrations juvenile alligators remain even stimulation luteinizing hormone data suggest gonads juveniles lake apopka permanently modified ovo normal steroidogenesis possible thus normal sexual maturation unlikely