Firdausi Qadri|Amit Saha|Tanvir Ahmed|Abdullah A. Tarique|Yasmin Begum|Ann?Mari Svennerholm
Disease Burden Due to Enterotoxigenic <i>Escherichia coli</i> in the First 2 Years of Life in an Urban Community in Bangladesh
International Centre for Diarrhoeal Disease Research|International Centre for Diarrhoeal Disease Research|International Centre for Diarrhoeal Disease Research|International Centre for Diarrhoeal Disease Research|International Centre for Diarrhoeal Disease Research|University of Gothenburg
cohort 321 children followed birth 2 years age determine incidence enterotoxigenic escherichia coli etec bangladesh average number diarrheal days incidence rates 66 23childyear respectively etec common pathogen isolated 195 cases incidence 05 episodechildyear prevalence rotavirus diarrhea lower 10 etec expressing heatstable enterotoxin st predominant strains isolated diarrheal cases positive colonization factors cfs higher frequency 66 healthy children 33 p 0001 heatlabile toxin ltpositive strains healthy children often cf negative 92 isolated children diarrhea 73 p 0001 children symptomatic asymptomatic infections cfai cs1 plus cs3 cs2 plus cs3 cs5 plus cs6 strains repeat episode diarrhea infection homologous cf type uncommon repeat symptomatic infections noted mostly lt stexpressing etec etec diarrhea prevalent children ab groups blood group p 0032 0023 children etec diarrhea underweight growth stunted 2year followup period showing importance strategies prevent decrease etec diarrheal morbidity children