Alexi A. Wright|Nikita Raman|Patrick Staples|Stephanie Schonholz|Angel M. Cronin|Kenzie W. Carlson|Nancy L. Keating|Jukka?Pekka Onnela
The HOPE Pilot Study: Harnessing Patient-Reported Outcomes and Biometric Data to Enhance Cancer Care
Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute|Brigham and Women's Hospital|Harvard University|Dana-Farber Cancer Institute
integrating patientreported outcomes pros clinical practice increasingly promising strategy improving patients symptoms communication clinical outcomes objective current study assess feasibility acceptability perceived effectiveness mobile health intervention designed collect pros activity data measure health statusthis work pilot intervention 10 patients gynecologic cancers received palliative chemotherapy hope helping patients excel study used wearable accelerometers assess physical activity beiwe research platform collect pros stratify patient responses risk provide tailored symptom management notify patients clinicians highrisk symptoms feasibility acceptability assessed enrollment adherence rates perceived effectiveness evaluated patients oncologists study completionthe approachtoconsent rate 100 participants 90 70 adherent wearable accelerometers smartphone surveys respectively participants mean daily step count 3973 standard deviation sd 2305 steps increased week 1 mean 3520 steps sd 1937 steps week 3 mean 4136 steps sd 1578 steps active monitoring participants heart rates daily steps pros throughout study identified anomalies participants behavior patterns suggested poor health two patients 20 patients clinicians indicated intervention improved physical activity communication symptom managementa mobile health intervention collects pros activity data measure health status feasible acceptable perceived effective improving symptom management patients advanced gynecologic cancers larger multisite randomized clinical trial assess efficacy hope intervention patients symptoms healthrelated quality life clinical outcomes health care use warranted