Nicholas J. Ainsworth|Hailey Wright|Ksenya Tereshchenko|Daniel M. Blumberger|Alastair J. Flint|Eric J. Lenze|Athina Perivolaris|Benoit H. Mulsant
Recruiting for a Randomized Clinical Trial for Late-Life Depression During COVID-19: Outcomes of Provider Referrals Versus Facebook Self-Referrals
Centre for Addiction and Mental Health|University of Toronto|Centre for Addiction and Mental Health|Centre for Addiction and Mental Health|Centre for Addiction and Mental Health|University of Toronto|University of Toronto|University Health Network|Toronto General Hospital|Washington University in St. Louis|Centre for Addiction and Mental Health|Centre for Addiction and Mental Health|University of Toronto
evaluate effectiveness online recruitment clinical trial pharmacotherapy latelife depression covid19the authors calculated yield defined recruitment leading randomization enrollment provider referrals versus facebook selfreferrals compared characteristics dropout rates participants source analyzed correlations stringency public health restrictions referrals source timeprovider referrals significantly higher yield 10 33 referrals 303 versus facebook selfreferrals 14 323 43 p 000001 participants selfreferred facebook significantly education otherwise groups similar characteristics dropout rates public health stringency negatively correlated provider referrals 032 positively correlated facebook selfreferrals 039 neither association reached statistical significanceonline recruitment may improve access clinical research older depressed adults future studies evaluate costeffectiveness potential barriers computer literacy