Ruth D. Ellis|Issaka Sagara|Anna P. Durbin|Alassane Dicko|Donna Shaffer|Louis H. Miller|Mahamadoun H. Assadou|M. Kone|Beh Kamaté|Ousmane Guindo|Michael P. Fay|Dapa A. Diallo|Ogobara K. Doumbo|Ezekiel J. Emanuel|Joseph Millum
Comparing the Understanding of Subjects Receiving a Candidate Malaria Vaccine in the United States and Mali
National Institute of Allergy and Infectious Diseases|National Institutes of Health
initial responses questionnaires used assess participants understanding informed consent malaria vaccine trials conducted united states mali tallied total scores analyzed age sex literacy known location ninetytwo percent 92 answers united states participants 85 answers malian participants correct questions likely answered incorrectly mali related risk type vaccine adult participants independent predictors higher scores younger age female sex united states male sex mali scores united states higher mali p 0005 despite difference participants sites well informed overall although interpretation must qualified questionnaires intended research tools standardized among sites results support concerns systematic low understanding among research participants developing versus developed countries