John P. Aggleton|Seralynne D. Vann|Christine Denby|Sophie Dix|Andrew R. Mayes|Neil Roberts|Andrew P. Yonelinas
Sparing of the familiarity component of recognition memory in a patient with hippocampal pathology
Cardiff University|Cardiff University|University of Liverpool|Eli Lilly (United Kingdom)|University of Liverpool|University of Liverpool|University of California, Davis
subject kn persistent anterograde amnesia result brain injury following meningitis 1993 mri scans reveal bilateral decrease volume hippocampal region dentate gyrus ca14 subicular cortices approximately 45 right left hemispheres although volume perirhinal cortex appears normal aside changes occipital lobe bilateral shrinkage amygdala rest brain appears normal recent quantitative mri scans striking feature memory loss ability perform normal levels tests recognition despite consistent deficit tests recall two tests designed specifically distinguish performance two putative divisions recognition memory rememberknow procedure use receiver operating characteristics distinguish familiarity recollection provide evidence selective sparing familiarity component recognition dissociation within recognition memory supports dualprocess models recognition also supports proposals anatomically linked regions within medial temporal lobe make qualitatively different contributions recognition