Miel Vugts|Margot C. W. Joosen|Jessica E van der Geer|A.M.E.E. Zedlitz|Hubertus J. M. Vrijhoef
The effectiveness of various computer-based interventions for patients with chronic pain or functional somatic syndromes: A systematic review and meta-analysis
Tilburg University|Tilburg University|Leiden University|Leiden University|Vrije Universiteit Brussel|Maastricht University
computerbased interventions target improvement physical emotional functioning patients chronic pain functional somatic syndromes however unclear extent interventions work systematic review metaanalysis registered prospero 2016 crd42016050839 assesses efficacy relative passive active control conditions explores patient intervention factors controlled studies identified medline embase psychinfo web science cochrane library pooled standardized mean differences comparison type somatic symptom healthrelated quality life functional interference catastrophizing depression outcomes calculated posttreatment 6 months followup risk bias assessed subgroup analyses performed patient intervention characteristics heterogeneous outcomes observed maximally 30 46 eligible studies 3387 participants included per metaanalysis mostly internetbased cognitive behavioral therapies identified significantly higher patient reported outcomes found comparisons passive control groups standardized mean differences ranged 41 18 comparisons active control groups smd 26 14 outcomes significant heterogeneity related patient intervention characteristics conclude minority good quality evidence small positive average effects computerbased cognitive behavior change interventions similar traditional modes effects may sustainable indications found interventions work better consistently across outcomes patients future process analyses recommended aim better understanding individual chances clinically relevant outcomes