Kam S. Woo|Ping Chook|Olli T. Raitakari|Brendan McQuillan|Jiang Zheng Feng|David S. Celermajer
Westernization of Chinese Adults and Increased Subclinical Atherosclerosis
Sir Charles Gairdner Hospital|Chinese University of Hong Kong|Royal Prince Alfred Hospital|Sir Charles Gairdner Hospital|Chinese University of Hong Kong|Royal Prince Alfred Hospital|Sir Charles Gairdner Hospital|Chinese University of Hong Kong|Royal Prince Alfred Hospital|Sir Charles Gairdner Hospital|Chinese University of Hong Kong|Royal Prince Alfred Hospital|Sir Charles Gairdner Hospital|Chinese University of Hong Kong|Royal Prince Alfred Hospital|Sir Charles Gairdner Hospital|Chinese University of Hong Kong|Royal Prince Alfred Hospital
abstract cardiovascular event rates much lower china compared developed countries westernization diet lifestyle chinese however may lead increased prevalence atherosclerosisrelated diseases carotid intimamedia thickness imt marker subclinical atherosclerosis examined imt vascular risk profile communitybased groups rural chinese westernized urban chinese urban whites mean imt common carotid artery measured 348 healthy adults aged 4213 years range 21 71 years 116 subjects rural china 116 urban chinese subjects living hong kong australia 116 urban caucasians living australia 3 groups matched age sex cigarette smoke exposure urban chinese subjects slightly better risk factor profile higher hdlcholesterol lower blood pressure compared rural chinese subjects despite however mean imt lowest rural chinese 050010 mm intermediate urban chinese 056012 mm highest urban whites 064013 mm p lt0001 comparisons groups differences imt altered adjustment major traditional cardiovascular risk factors serum lipids smoking blood pressure body mass index influence vascular risk factors atherosclerosis urban versus rural chinese subjects studied multivariate regression models comparing steepness regression slopes risk factors imt subject groups effects smoking hdlcholesterol triglycerides imt significantly greater urban compared rural chinese p lt001 data suggest westernization chinese subjects associated greater susceptibility proatherogenic effects traditional vascular risk factors lipids smoking evidence increased imt marker subclinical atherosclerosis