Nadia Akseer|Seema Mehta|Jannah Wigle|Rupinder Chera|Zane Brickman|Sara Al?Gashm|B Sorichetti|Ashley Vandermorris|David Hipgrave|Nina Schwalbe|Zulfiqar A. Bhutta
Non-communicable diseases among adolescents: current status, determinants, interventions and policies
Hospital for Sick Children|Hospital for Sick Children|Hospital for Sick Children|Hospital for Sick Children|Hospital for Sick Children|Hospital for Sick Children|Public Health Ontario|University of Toronto|Hospital for Sick Children|United Nations Children's Fund|Spark Therapeutics (United States)|Public Health Ontario|University of Toronto
addressing noncommunicable disease ncds global priority sustainable development goals especially adolescents however existing literature ncd burden risk factors determinants effective interventions policies targeting diseases adolescents limited study develops evidencebased conceptual framework highlights pathways risk factors interventions ncd development adolescence ages 1019 years continuing adulthood additionally epidemiologic profile key ncd risk factors outcomes among adolescents preventative ncd policieslawslegislations examined multivariable analysis conducted explore determinants ncds among adolescents adultswe reviewed literature develop adolescentspecific conceptual framework ncds global data repositories searched janjuly 2018 data ncdrelated risk factors outcomes policy data 194 countries 1990 2016 disabilityadjusted life years used assess disease burden hierarchical modeling approach ordinary least squares regression used explore basic underlying causes ncd burdenmental health disorders common ncds found adolescents adverse behaviours lifestyle factors specifically smoking alcohol drug use poor diet metabolic syndrome key risk factors ncd development adolescence across countries laws policies preventing ncdrelated risk factors exist however targeting contraceptive use drug harm reduction mental health nutrition generally limited many effective interventions ncd prevention exist must implemented scale multisectoral action utilizing diverse delivery mechanisms multivariable analyses showed structuralmacro community household factors significant associations ncd burden among adolescents adultsmultisectoral efforts needed target ncd risk factors among adolescents mitigate disease burden adverse outcomes adulthood findings could guide policy programming reduce ncd burden sustainable development era