Kenny Lawson|Stewart W Mercer|Sally Wyke|Eleanor Grieve|Bruce Guthrie|Graham Watt|Elisabeth Fenwick
Double trouble: the impact of multimorbidity and deprivation on preference-weighted health related quality of life a cross sectional analysis of the Scottish Health Survey
University of Glasgow|University of Glasgow|University of Glasgow|University of Glasgow|University of Dundee|University of Glasgow|University of Glasgow
investigate association multimorbidity preferenceweighted health related quality life pwhrqol score combines physical mental functioning varies socioeconomic deprivation age scottish health survey shes crosssectional representative survey general population included sf12 survey hrqol individuals 20 years 7054 participants generated pwhrqol scores running sf12 responses sf6d algorithm resulting scores ranged 029 worst health 1 perfect health using ordinary least squares first investigated associations scores increasing counts longstanding conditions repeated multimorbidity 2 conditions estimates made general population quintiles socioeconomic deprivation multimorbidity analyses repeated stratifying population age group 2044 4564 65 45 participants reported longstanding condition 18 reported multimorbidity presence 1 2 3 longstanding conditions associated average reductions pwhrqol scores 0081 0151 0212 respectively reduction scores associated multimorbidity 33 greater deprived quintile compared least deprived quintile biggest difference 80 2044 age groups significant gender differences pwhrqol decreases markedly multimorbidity exacerbated higher deprivation younger age need prioritise interventions improve hrqol especially younger adults multimorbidity deprived areas known prevalence premature onset multimorbidity increases socioeconomic position worsens previous studies investigated effect multimorbidity health related quality life hrqol separate physical mental health states limited data hrqol falls number conditions increase estimates vary across general population leaving physical mental health separate categories inhibit assessment overall hrqol use preferenceweighted health related quality life pwhrqol score provides single summary measure overall health weighting mental physical states perceived importance part overall hrqol use single score enables simple consistent assessment impact conditions varies across population economists term pwhrqol scores health utilities study adds first study estimate impact multimorbidity pwhrqol scores varies age group socioeconomic deprivation multimorbidity substantial negative impact hrqol severe areas deprivation especially younger adults measuring burden multimorbidity using pwhrqol provides consistency economists measure hrqol changes used economic evaluation assess cost effectiveness interventions