Chandra Y. Osborn|Leonard E. Egede
The relationship between depressive symptoms and medication nonadherence in type 2 diabetes: the role of social support
Vanderbilt University|Medical University of South Carolina|Ralph H. Johnson VA Medical Center
medication adherence promotion interventions needed target modifiable behavioral factors contributing link depressive symptoms poor adherence diabetes selfcare behaviors effort identify factors contribute link examined role social support mediator relationship depressive symptoms medication nonadherence recruited 139 subjects type 2 diabetes using indirect effect test biascorrected bc bootstrapping tested whether depressive symptoms indirect effect medication nonadherence lack social support depressive symptoms associated medication nonadherence total effect06 p001 depressive symptoms associated less social support direct effect predictor mediator96 p02 less social support associated medication nonadherence direct effect mediator outcome01 p01 relationship depressive symptoms medication nonadherence persisted social support predicted pathway degree relationship partially explained relationship depressive symptoms less social support indirect effect01 95 bc bootstrapped confidence interval 0005 0325 providing social support patients diabetes symptoms depression may ameliorate deleterious effects depressive symptoms medication nonadherence social support alone enough