Joey Z Gu, Grayson L Baird, Antonio Escamilla Guevara, Young-Jin Sohn, Melis Lydston, Christopher Doyle, Sarah E A Tevis, Randy C Miles
A systematic review and meta-analysis of English language online patient education materials in breast cancer: Is readability the only story?
Breast (Edinburgh, Scotland)
studies noted variations costeffectiveness schoollocated influenza vaccination sliv little known slivs costeffectiveness may vary targeted age group eg elementary secondary school students vaccine consent process paperbased webbased slivs costeffectiveness may impacted spillover effect practicebased vaccination prior studies addressed issue performed costeffectiveness analysis two sliv programs upstate new york 20152016 elementary school sliv using stepped wedge design schools clusters 24 suburban 18 urban schools b secondary school sliv using cluster randomized trial 16 suburban 4 urban schools costperadditionallyvaccinated child ie incremental costeffectiveness ratio icer estimated dividing incremental sliv intervention cost incremental effectiveness ie additional number vaccinated students intervention schools compared control schools performed deterministic analyses oneway sensitivity analyses probabilistic analyses overall effectiveness measure proportion children vaccinated 57 55 percentage points higher respectively intervention elementary 528 secondary schools 482 gradematched control schools sliv programs vaccinated small proportion children intervention elementary 52 secondary schools 25 elementary secondary schools icer excluding vaccine purchase 8571 8651 peradditionallyvaccinatedchild respectively additionally accounting observed spillover impact practicebased vaccination icer decreased 8053 elementary schools decreasing substantially secondary schools 5340 estimates higher published practicebased vaccination cost median 2550 mean 4548 also estimates higher 20092011 urban sliv program mean costs 65 due additional costs use new webbased consent system 1297 peradditionallyvaccinatedchild higher project coordination costs 20152016 oneway sensitivity analyses showed icer estimates sensitive sliv effectiveness sliv raises vaccination rates may increase practicebased vaccination primary care practices sliv programs effective costeffective practicebased vaccination sliv programs would need vaccinate students andor lower costs consent systems project coordination clinicaltrialsgov nct02227186 august 25 2014 updated nct03137667 may 2 2017