Otis W. Brawley
Trends in Prostate Cancer in the United States
American Cancer Society|Emory University
united states prostate cancer commonly diagnosed nonskin cancer second leading cause cancer death american cancer society estimates 241 740 american men diagnosed disease 28 170 men die 2012 prostate cancer demographics changed dramatically past 30 years prostate cancer ageadjusted incidence rate increased 1980s peaked early mid1990s incidence rate declined since american mortality rates rose 1980s peaked 1991 today american incidence rates 1975 levels incidence rate 5year survival rates heavily influenced introduction serum prostatespecific antigen test widespread use cancer screening effect screening prostate cancer mortality less certain screening caused dramatic increase number proportion men diagnosed localized disease outcomes studies among men treated radical prostatectomy show greater 30 serum prostatespecific antigen relapse rates common suggests many men diagnosed localized early stage disease actually apparently localized early stage disease really lowvolume metastatic disease