Jane Ewing|Madeleine King|Narelle Smith
Validation of modified forms of the PedsQL generic core scales and cancer module scales for adolescents and young adults (AYA) with cancer or a blood disorder
University of Technology Sydney|University of Sydney|University of Technology Sydney
validate two healthrelated quality life hrqol measures pedsql generic core cancer module adolescent forms 1318 years modification 1625yearold adolescents young adults aya cancer blood disorderaya patients nominated proxies recruited three sydney hospitals modified forms administered telephone clinicswards analyses included correlations factor analysis analysis variance knowngroups defined memorial symptom assessment scaleeightyeight patients 79 proxies completed questionnaires factor structures consistent unmodified forms confirmed construct validity cronbachs alpha ranged 081098 interscale correlations hypothesized confirming discriminant validity statistically significant differences groups mild moderate severe symptoms p 005 confirmed clinical validitythese modified forms provide reliable valid measures hrqol aya cancer blood disorder suitable clinical trials research practice