Amnon Sonnenberg, Judith F Collins
Vicious circles in inflammatory bowel disease
Inflammatory bowel diseases
lactococcus lactis strain plasma lcplasma reported antiviral effects via direct activation plasmacytoid dendritic cells upregulate production type iii interferons randomized placebocontrolled doubleblind parallel group study designed elementary schoolchildren grades 1 3 vietnam lcplasma control administered schoolchildren beverage 10 1011 count lcplasmadayperson primary endpoint determine efficacy lcplasma reducing cumulative days absent school due upper respiratory disease urid gastrointestinal disease gid secondary endpoint evaluate potency lcplasma uridgid symptoms general wellbeing scores lcplasma intake significantly reduced cumulative days absent school due uridgid odds ratio 057 p 0004 urid alone 056 p 0005 lcplasma also significantly reduced number cumulative fever positive days first 4 weeks intervention 058 p 0001 cumulative days diarrhea last 4 weeks intervention period 078 p 001 number positive general wellbeing days significantly improved lcplasma group compared control throughout intervention period 093 093 p 003 004 first last 4 weeks intervention respectively data suggest lcplasma seems improve health condition elementary schoolchildren reduces school absenteeism due infectious disease especially urid