Sylvain Iceta, Léonie Sohier, Catherine Bégin, Anne-Sophie Brazeau, Rémi Rabasa-Lhoret, Claudia Gagnon
Impact of glycemic variability on cognitive impairment, disordered eating behaviors and self-management skills in patients with type 1 diabetes: study protocol for a cross-sectional online study, the Sugar Swing study
BMC endocrine disorders
predicting hiv therapy outcomes critical clinical question whether using historical information enhance predictive capabilities compared current latest available data analysis study analyses whether historical knowledge includes viral mutations detected genotypic tests therapy temporal occurrence concomitant viral load measurements bring improvements introduce method weigh mutations considering previously enumerated factors reference mutationdrug stanford resistance tables compare model encompassing history h one using information nh hmodel demonstrates superior discriminative ability higher rocauc score 7634 nhmodel 7498 wilcoxon test results confirm significant improvement predictive accuracy treatment outcomes incorporating historical information increased performance hmodel might attributed consideration latent hiv reservoirs probably obtained leveraging historical information findings emphasize importance temporal dynamics acquiring mutations however result also shows prediction accuracy remains relatively high even historical information available supplementary material available