Ch Kouimtsidis, St John-Smith, P Kemp, G Ikkos
Evidence based mental healthcare and service innovation: review of concepts and challenges
Psychiatrike = Psychiatriki
wellestablished chronic exposure environmental toxins adverse effects neuropsychological health particularly developing youths however home radon ubiquitous radiotoxin seldom studied context present study investigated degree chronic everyday home radon exposure associated alterations transdiagnostic mental health outcomes total 59 children adolescents ages 6 14yearsold 1047 years sd 258 28 males completed study parents completed questionnaires detailing aspects attention executive function used principal components analysis derive three domains neuropsychological functioning 1 taskbased executive function skills 2 selfand emotionregulation abilities 3 inhibitory control additionally parents completed home radon test kit provided information long child lived tested home computed radon exposure index per person based duration time child lived home measured home radon concentration youths divided terciles based radon exposure index score using mancova design determined whether differences neuropsychological domain scores across three groups controlling age sex socioeconomic status significant multivariate effect radon group neuropsychological dysfunction 077 f 232 p 0038 p2 012 examination univariate effects revealed specific increases selfand emotionregulation dysfunction among youths greatest degree chronic home radon exposure f 721 p 0002 p2 021 significant differences group tested domains data suggest potential specificity neurotoxic effects everyday home radon exposure developing youths significant aberrations selfand emotionregulation faculties findings support need better public awareness public health policy surrounding home radon safety mitigation strategies