Vivechkanand S Chunoo, Brittany Devies
Culturally relevant leadership learning in action: Applying CRLL to curriculum development and program design
New directions for student leadership
hybrids species often sterile inviable form reproductive isolation thought evolve via accumulation mutations interact reduce fitness combined hybrids mathematical formulations dobzhanskymuller model predict accelerating buildup hybrid incompatibilities divergence time snowball effect although dobzhanskymuller model widely accepted snowball effect tested two species groups evaluated evidence snowball effect evolution hybrid male sterility among subspecies house mice recently diverged group shows partial reproductive isolation compared history subspecies divergence patterns quantitative trait loci qtl detected f2 intercrosses two pairs subspecies mus musculus domesticus musculus domesticus castaneus used recently developed phylogenetic comparative method statistically measure fit data snowball prediction apply method qtl partitioned either shared unshared two crosses heuristic partitioning based overlap qtl confidence intervals produced unambiguous support snowball effect alternative approach combining data among crosses favored snowball effect autosomes linear accumulation incompatibilities x chromosome reasoning x chromosome analyses complicated low mapping resolution conclude hybrid male sterility loci snowballed house mice study illustrates power comparative genetic mapping understanding mechanisms speciation