Dubravko Habek, Tatjana Dujaković, Jasna Cerkez Habek, Ivana Jurković
TWENTY-THREE-YEAR LONG-TERM HEALTH OUTCOME AFTER THE WAR IN VUKOVAR
Acta clinica Croatica
review available medical literature elucidate association childhood sexual abuse development irritable bowel syndrome later life systematic review conducted january august 2022 comprised literature search medline via pubmed scopus embase web science google scholar databases relevant studies published 2001 2021 newcastleottawa scale used determine quality studies data prevalence irritable bowel syndrome metaanalysed using mantelhaenszel randomeffects model revman 541 7 observational studies analyzed detail 5 714 casecontrol design 2 286 crosssectional studies overall 3156 subjects prevalence irritable bowel syndrome childhood sexual abuse group 5186 334644 3674 9232512 nonchildhood sexual abuse group pooled odds ratio indicating association childhood sexual abuse irritable bowel syndrome 187 95 confidence interval 156226 study quality rated good 3 428 cases fair 3 428 poor 1 143 childhood sexual abuse found significantly associated development irritable bowel syndrome later life strengthening argument childhood sexual abuse lead longterm detriments extending adulthood however existing literature found stratified aspects irritable bowel syndrome including symptom severity childhood sexual abuse exclusive cause irritable bowel syndrome