Elle Mizuki Fukui, Patrick G Lyons, Emily Harris, Emma K McCune, Juan C Rojas, Lekshmi Santhosh
Improving Communication in Intensive Care Unit to Ward Transitions: Protocol for Multisite National Implementation of the ICU-PAUSE Handoff Tool
JMIR research protocols
increasing evidence suggests inflammatory biomarkers play significant role cerebral venous sinus thrombosis cvst neutrophiltolymphocyte ratio nlr platelettolymphocyte ratio plr monocytetolymphocyte ratio mlr related thrombotic conditions indicators systemic inflammation analyze correlation inflammatory biomarkers extent thrombus determined cvstscore total 40 patients cvst 24 female subjects 60 40 age sexmatched healthy controls retrospectively evaluated inflammatory biomarkers including creactive protein crp plr nlr mlr cvstscore recorded assess relationship biomarkers thrombus burden patients grouped according symptom duration group 1 03 days group 2 47 days group 3 830 days compare biomarker levels crp nlr plr significantly higher cvst group p 0001 p 0003 p 0014 respectively nlr plr presented significant positive correlation cvstscore p 0003 r 0464 p 0040 r 0326 respectively nlr significantly higher group 1 compared groups 2 3 p 0016 p 0014 respectively group 1 stronger positive correlation cvstscore nlr p 0026 r 0591 plr p 0012 r 0648 multiple linear regression analysis revealed nlr key factor predicting cvstscore p 0019 nlr plr associated thrombus burden cvst especially patients admitted hospital early stages nlr independent factor predict thrombus burden cvst