Mary Whitten, Sheri P Silfies, Namrata Grampurohit, Jane M Fedorczyk
A modified-delphi study establishing consensus in the therapeutic management of posttrauamtic elbow stiffness
Journal of hand therapy : official journal of the American Society of Hand Therapists
infectious diseases great threat human health rapid accurate detection pathogens important diagnosis treatment infectious diseases metagenomics nextgeneration sequencing mngs unbiased comprehensive approach detecting rna dna sample development sequencing bioinformatics technologies mngs moving research clinical application opens new avenue pathogen detection numerous studies revealed good potential clinical application mngs infectious diseases especially difficulttodetect rare novel pathogens however several hurdles clinical application mngs 1 lack universal workflow validation quality assurance 2 insensitivity highhost background lowbiomass samples 3 lack standardized instructions mass data analysis report interpretation therefore complete understanding new technology help promote clinical application mngs infectious diseases review briefly introduces history nextgeneration sequencing mainstream sequencing platforms mngs workflow discusses clinical applications mngs infectious diseases advantages disadvantages