Maria Kaltsa, Despina Papadopoulou
The Processing of Lexical Ambiguity: Evidence from Child and Adult Greek
Journal of psycholinguistic research
important need methods process myocardial perfusion imaging mpi singlephoton emission computed tomography spect images acquired lowerradiation dose andor acquisition time processed images improve observer performance clinical task detecting perfusion defects compared lowdose images address need build upon concepts modelobserver theory understanding human visual system propose detection taskspecific deeplearningbased approach denoising mpi spect images demist approach performing denoising designed preserve features influence observer performance detection tasks objectively evaluated demist task detecting perfusion defects using retrospective study anonymized clinical data patients underwent mpi studies across two scanners n 338 evaluation performed lowdose levels 625 125 25 using anthropomorphic channelized hotelling observer performance quantified using area receiver operating characteristics curve auc images denoised demist yielded significantly higher auc compared corresponding lowdose images images denoised commonly used taskagnostic deep learningbased denoising method similar results observed stratified analysis based patient sex defect type additionally demist improved visual fidelity lowdose images quantified using root mean squared error structural similarity index metric mathematical analysis revealed demist preserved features assist detection tasks improving noise properties resulting improved observer performance results provide strong evidence clinical evaluation demist denoise lowcount images mpi spect