Anca Antoaneta Vărzaru
Unveiling Digital Transformation: A Catalyst for Enhancing Food Security and Achieving Sustainable Development Goals at the European Union Level
Foods (Basel, Switzerland)
migrants mainly undocumented lowincome refugees high risk hepatitis c virus hcv infection difficulttoreach totreat population aim study evaluate effectiveness test treat model directacting antiviral hcv infection migrants coming lowincome living southern italy prospective multicenter collaborative study based fourphaseprogram educational counseling screening linkagetocare treatment designed southern italy study started june 2018 stopped february 2020 outbreak sarscov2 infection italy resumed february 2021 november 2021 educational counseling infectious diseases transmitted blood sexually pseudonymized hcv screening offered undocumented migrants lowincome refugees observed one 1st level clinical centers hcvrnapositive subjects referred one 3rd level units infectious diseases id treated 12week course sofosbuvirvelpatasvir observed 12 weeks end direct antiviral agents daa treatment descriptive analysis categorical variables reported absolute numbers relative frequencies continuous variables summarized mean standard deviation sd normally distributed median interquartile range iqr normally distributed used pearson chisquare fishers exact test categorical variables students test mannwhitney test continuous variables p value 005 considered statistically significant analyses performed spss 210 3501migrants observed study period 3417 976 agreed screened 185 47 antihcvpositive 53 286 hcvrnapositive 53 subjects 48 905 referred id unit started daa treatment hcvrnapositivesubjects older median 36 years iqr 3221 vs 2719 iqr 3051925 p 0001 less frequently males 35 6603 vs 119 901 p 0 0001 seronegative participants frequently came eastern europe 708 stayed longer italy months stay italy mean sd 5102 5284 vs 257 4265 p 0001 years schooling years schooling mean sd 961281 vs 710 4 p 00001 hcvrnapositivesubjects less frequently reported piercing tattoos tribal scars risk factors 236 48 hcv rna positive subjects started daa 47 979 showed sustained virological response one droppedout followup daa treatment subject adverse event model hcv screening linkage care seems effective eliminate hcv infectionin difficulttoreach totreat population undocumented migrants lowincome refugees participation cultural mediators study made possible better interaction migrants physicians evident large number subjects enrolled eliminating hcv among migrants longterm positive impact public health healthcare perspective reducing number individuals potentially develop hcvrelated complications liver cirrhosis hepatocellular carcinoma reducing circulation hcv regions host often case italy low endemic hcv infection