Mili Saha, Shobha Islam, Asma Akter Akhi, Goutam Saha
Factors affecting success and failure in higher education mathematics: Students' and teachers' perspectives
Heliyon
association coeliac disease type 1 diabetes well documented association coeliac disease type 2 diabetes risk remains undetermined conducted nationwide cohort mendelian randomisation analysis investigate link nationwide matched cohort used data swedish espresso cohort including 46150 individuals coeliac disease 219763 matched individuals comparator group selected general population followed 1969 2021 data 9053 individuals coeliac disease underwent second biopsy used examine association persistent villous atrophy type 2 diabetes multivariable cox regression employed estimate associations mendelian randomisation analysis 37 independent genetic variants associated clinically diagnosed coeliac disease p5108 used proxy genetic liability coeliac disease summarylevel data type 2 diabetes obtained diagram consortium 80154 cases finngen study 42593 cases median 157 years followup 6132 133 30138 137 incident cases type 2 diabetes people coeliac disease comparator individuals respectively coeliac disease increased risk incident type 2 diabetes hr 100 95 ci 097 103 compared comparator individuals persistent villous atrophy associated increased risk type 2 diabetes compared mucosal healing among participants coeliac disease hr 102 95 ci 090 116 genetic liability coeliac disease associated type 2 diabetes diagram 101 95 ci 099 103 finngen 101 95 ci 099104 coeliac disease associated type 2 diabetes risk