Ingrid T. Katz|Erin Leister|Deborah Kacanek|Michael D. Hughes|Arlene Bardeguez|Elizabeth Livingston|Alice Stek|David E. Shapiro|Ruth Tuomala
Factors Associated With Lack of Viral Suppression at Delivery Among Highly Active Antiretroviral Therapy–Naive Women With HIV
Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital|Brigham and Women's Hospital|Duke University|Harvard University|University of Southern California|Massachusetts General Hospital
high delivery maternal plasma hiv1 rna level viral load vl risk factor mothertochild transmission poor maternal healthto identify factors associated detectable vl delivery despite initiation highly active antiretroviral therapy haart pregnancymulticenter observational study clinicaltrialgov nct0002814567 us aids clinical research sitespregnant women hiv initiated haart pregnancydescriptive summaries associations among sociodemographic hiv disease treatment characteristics pregnancyrelated risk factors detectable vl 400 copiesml deliverybetween 2002 2011 671 women met inclusion criteria 131 detectable vl delivery factors associated detectable vl included multiparity 164 vs 80 nulliparity p 0002 black ethnicity 176 vs 66 hispanic 66 white p 0001 11th grade education less 176 vs 121 high school diploma p 0013 initiation haart third trimester 239 vs 123 86 second trimesters respectively p 0003 hiv diagnosis current pregnancy 161 vs 110 current pregnancy p 0051 first prenatal visit third trimester 333 vs 143 105 second third trimesters respectively p 0002 women treatment interruptions reported poor medication adherence likely detectable vl deliverydata many covariates incomplete women entered study varying times pregnancya total 131 women initiated haart pregnancy detectable vl delivery timing haart initiation prenatal care along medication adherence pregnancy associated detectable vl delivery social factors including ethnicity education may help identify women could benefit focused efforts promote early haart initiation adherenceus department health human services