Michelle Dean, Ya-Chih Chang, Wendy Shih, Felice Orlich, Connie Kasari
Social engagement and loneliness in school-age autistic girls and boys
Women's health (London, England)
bioprocessing industry undergoing significant transformation approach quality assurance shifting traditional quality testing qbt quality design qbd qbd systematic approach quality process development integrates quality process design control guided regulatory frameworks paradigm shift enables increased operational efficiencies reduced market time ensures product consistency implementation qbd framed around key elements defining quality target product profile qtpps identifying critical quality attributes cqas developing design spaces ds establishing control strategies cs maintaining continual improvement present critical analysis delves intricacies element emphasizing role ensuring consistent product quality regulatory compliance integration industry 40 50 technologies including artificial intelligence ai machine learning ml internet things iot digital twins dts significantly transforming bioprocessing industry innovations enable realtime data analysis predictive modelling process optimization crucial elements qbd implementation among concept dts notable ability facilitate bidirectional data communication enable realtime adjustments therefore optimize processes dts however face implementation challenges system integration data security hardwaresoftware compatibility challenges addressed advancements ai virtual reality augmented reality vrar improved communication technologies central functioning dts development application various models differing types mechanistic empirical hybrid models serve intellectual backbone dts providing framework interpreting predicting behaviour physical counterparts choice development models vital accuracy efficacy dts enabling mirror predict realtime dynamics bioprocessing systems complementing models advancements data collection technologies freefloating wireless sensors spectroscopic sensors enhance monitoring control capabilities dts providing comprehensive nuanced understanding bioprocessing environment review offers critical analysis prevailing trends modelbased bioprocessing development within sector