Bethany White|Annie Madden|Margaret Hellard|Thomas Kerr|Maria Prins|Kimberly Page|Gregory J. Dore|Lisa Maher
Increased hepatitis <scp>C</scp> virus vaccine clinical trial literacy following a brief intervention among people who inject drugs
UNSW Sydney|Alcohol and Drug Foundation|Burnet Institute|AIDS Vancouver|University of British Columbia|University of Amsterdam|Public Health Service of Amsterdam|University of California, San Francisco|UNSW Sydney|UNSW Sydney
abstract introduction aims people inject drugs high risk hepatitis c virus hcv infection target population future hcv vaccine trials little known clinical trial literacy ctl group assessed impact brief intervention bi designed improve hcv vaccine ctl among people inject drugs ydney ustralia design methods people inject drugs enrolled communitybased prospective observational study n ovember 2008 eptember 2010 n 102 completed ctl assessment followed immediately bi posttest assessment conducted 24 weeks results median age sample 27 years 73 male 60 10 less years schooling median time since first injection 5 years 20 reported daily frequent injecting mean number correct responses increased 53 6310 42 101df p lt 0001 24 weeks postintervention statistically significant differences observed three knowledge items higher proportions participants correctly answering questions related randomisation p 0002 blinding p 0005 vaccineinduced seropositivity p 0003 postintervention discussion conclusions significant increase hcv vaccine ctl observed suggesting new relatively novel concepts learned recalled group findings support feasibility future trials among population correction added 21 november 2012 first online publication tscore mean number correct responses corrected 42 results section white b madden hellard h kerr prins page k dore gj maher l increased hepatitis c virus vaccine clinical trial literacy following brief intervention among people inject drugs drug alcohol rev 201332419425