Haley N Boerckel, Lacy J Worden, Lisa A Salvati, Andrew P Jameson, Lisa E Dumkow
Impact of altered mental status on antibiotic prescribing and outcomes in hospitalized patients presenting with pyuria
Journal of the American Pharmacists Association : JAPhA
numerous epidemiological studies confirmed negative influences air pollutants human health fine particles pm25 nitrogen dioxide no2 cause highest health risks however traditional studies involved ambient concentration short medium time period ignores influence indoor sources individual timeactivity pattern fact health status impacted longterm accumulated exposure aim paper develop methodology simulate lifelong exposure rather outdoor concentration pm25 no2 individuals europe method realized developing probabilistic model integrates outdoor air quality model model estimating indoor air pollution exposure model life course trajectory model predicting retrospectively employment status approach applied samples two population studies frame european commission fp7environment research project heals health environmentwide associations based large population surveys socioeconomic data participants collected results show simulated exposures pollutants samples influenced sociodemographic characteristics including age gender residential location employment status smoking habits outdoor concentrations indoor sources play important role total exposure moreover large variances observed among countries cities application methodology provides valuable insights exposure modelling well important input data exploring correlation exposure health impacts