Darren A. DeWalt|Dean Schillinger|Bernice Ruo|Kirsten Bibbins?Domingo|David W. Baker|Mark Holmes|Morris Weinberger|Aurelia Macabasco?O’Connell|Kimberly A. Broucksou|Victoria Hawk|Kathleen L. Grady|Brian Erman|Carla A. Sueta|Patricia P. Chang|Crystal W. Cené|Jia Rong Wu|Christine Jones|Michael Pignone
Multisite Randomized Trial of a Single-Session Versus Multisession Literacy-Sensitive Self-Care Intervention for Patients With Heart Failure
Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco|Northwestern University|San Francisco General Hospital|University of California, San Francisco
selfcare training reduce hospitalization heart failure hf intensive intervention may benefit vulnerable patients including low literacya 1year multisite randomized controlled comparative effectiveness trial 605 patients hf conducted randomized single session received 40minute inperson literacysensitive training multisession group received initial training ongoing telephonebased support primary outcome combined incidence allcause hospitalization death secondary outcomes included hfrelated hospitalization hfrelated quality life prespecified stratification literacy overall incidence allcause hospitalization death differ intervention groups incidence rate ratio 101 95 confidence interval 083122 effect multisession training compared singlesession training differed literacy group among low literacy multisession training yielded lower incidence allcause hospitalization death incidence rate ratio 075 95 confidence interval 045125 among higher literacy multisession intervention yielded higher incidence incidence rate ratio 122 95 confidence interval 099150 interaction p0048 hfrelated hospitalization among low literacy multisession training yielded lower incidence incidence rate ratio 053 95 confidence interval 025112 among higher literacy yielded higher incidence incidence rate ratio 132 95 confidence interval 092188 interaction p0005 hfrelated quality life improved patients receiving multisession receiving singlesession interventions 1 6 months difference 12 months smaller effects hfrelated quality life differ literacyoverall intensive multisession intervention change clinical outcomes compared singlesession intervention people low literacy appear benefit multisession interventions people higher literacyurl httpwwwclinicaltrialsgov unique identifier nct00378950