Kim G Smolderen|Kelly M. Strait|Rachel P. Dreyer|Gail D’Onofrio|Shengfan Zhou|Judith H. Lichtman|Mary Geda|Héctor Bueno|John F. Beltrame|Basmah Safdar|Harlan M. Krumholz|John A. Spertus
Depressive Symptoms in Younger Women and Men With Acute Myocardial Infarction: Insights From the VIRGO Study
University of Missouri–Kansas City|Saint Luke's Hospital|Yale New Haven Hospital|Yale New Haven Hospital|Yale University|Yale New Haven Hospital|Yale New Haven Hospital|Yale New Haven Hospital|Hospital General Universitario Gregorio Marañón|Universidad Complutense de Madrid|Queen Elizabeth Hospital|University of Adelaide|Yale University|Yale New Haven Hospital|Robert Wood Johnson Foundation|Yale University|University of Missouri–Kansas City|Saint Luke's Hospital
depression recently recognized risk factor adverse medical outcomes patients acute myocardial infarction ami degree depression present among younger patients ami patient profile associated young ami patient depressive symptoms whether relevant sex differences exist currently unknownthe variation recovery role gender outcomes young ami patients virgo study enrolled 3572 patients ami 671 women 21 ratio women men 2008 2012 103 hospitals united states 24 spain 3 australia information lifetime history depression depressive symptoms experienced past 2 weeks patient health questionnaire cutoff score 10 used depression screening collected index ami admission information demographics socioeconomic status cardiovascular risk ami severity perceived stress 14item perceived stress scale health status seattle angina questionnaire euroqol 5d obtained interviews chart abstraction nearly half 48 women reported lifetime history depression versus 1 4 men 24 p00001 time admission ami women men experienced depressive symptoms 39 versus 22 p00001 adjusted odds ratio 164 95 ci 136 198 patients depressive symptoms higher levels stress worse quality life p0001 depressive symptoms prevalent among patients lower socioeconomic profiles eg lower education uninsured cardiovascular risk factors eg diabetes smokinga high rate lifetime history depression depressive symptoms time ami observed among younger women compared men depressive symptoms affected vulnerable socioeconomic clinical profiles