Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
Lancet (London, England)
exposure solar ultraviolet uv radiation use uvemitting tanning devices known risk factors skin cancer studies explored interaction risk factors namely risk skin cancer increases among exposed high levels natural sunlight regularly use tanning beds nurses health study ii followed 116430 women aged 2542 1991 2011 cumulative average uv exposure based participants residences followup periods history severe sunburn ages 1520 used proxy earlylife sunlight exposure tanning bed use early life data collected participants reported melanoma basal cell carcinoma bcc squamous cell carcinoma scc diagnoses built multivariable cox regression models estimate hazard ratios hrs 95 confidence intervals cis risk skin cancer associated joint effects sunlight exposure tanning bed use participants high sunlight exposure tanning bed use high schoolcollege increased risk bcc hr 153 95 ci 137171 pinteraction001 vs low sun exposure tanning bed use participants history severe sunburns tanning bed use high schoolcollege increased risk bcc hr 162 95 ci 147179 pinteraction002 vs sunburns tanning bed use significant interactions found sunlight exposure tanning bed use scc melanoma risk found significant interactions sunlight exposure tanning bed use risk bcc