Jagan A. Pillai|Linda K. McEvoy|Donald J. Hagler|Dominic Holland|Anders M. Dale|David P. Salmon|Douglas Galasko|Christine Fennema-Notestine
Higher education is not associated with greater cortical thickness in brain areas related to literacy or intelligence in normal aging or mild cognitive impairment
University of California, San Diego|University of California San Diego Medical Center|University of California, San Diego|University of California, San Diego|University of California, San Diego|University of California, San Diego|University of California, San Diego|University of California, San Diego|University of California San Diego Medical Center|University of California, San Diego
education may reduce risk dementia passive reserve increasing neural substrate tested hypotheses education associated thicker cortex reduced rates atrophy brain regions related literacy intellectual ability healthy older adults mild cognitive impairment categorized high 18 years low 13 years education groups higher education associated thinner cortices several areas oneyear atrophy rates areas differ education group results support passive reserve model earlylife education protects dementia increasing cortical thickness connectivity synaptic efficiency lifestyle factors may directly reflect cognitive reserve