Yao Yu, Guiyi Yang, Yixuan Qin, Linhan Fang, Yuxuan Liao, Wenxuan Bai, Jianzhen Wu, Pengfei Rong
The correlation between parents' education attainment and humanistic literacy of eight-year medical students
International journal of medical education
childhood nephrotic syndromes commonly caused one two idiopathic diseases minimalchange nephrotic syndrome mcns focal segmental glomerulosclerosis fsgs third distinct type membranous nephropathy rare children causes isolated nephrotic syndrome subdivided two major categories rare genetic disorders secondary diseases associated drugs infections neoplasia cause idiopathic nephrotic syndrome remains unknown evidence suggests may primary tcell disorder leads glomerular podocyte dysfunction genetic studies children familial nephrotic syndrome identified mutations genes encode important podocyte proteins patients idiopathic nephrotic syndrome initially treated corticosteroids steroidresponsiveness greater prognostic use renal histology several secondline drugs including alkylating agents ciclosporin levamisole may effective complicated steroidunresponsive mcns fsgs patients nephrotic syndrome associated several medical complications severe potentially fatal bacterial infections thromboembolism idiopathic nephrotic syndrome chronic relapsing disease steroidresponsive patients whereas children refractory fsgs ultimately develop endstage renal disease research done elucidate disorders molecular pathogenesis identify new prognostic indicators develop better approaches treatment