Nora Maria Raschle|Patrice L. Stering|Sarah Nadine Meissner|Nadine Gaab
Altered Neuronal Response During Rapid Auditory Processing and Its Relation to Phonological Processing in Prereading Children at Familial Risk for Dyslexia
Boston Children's Hospital|Harvard University|Boston Children's Hospital|Boston Children's Hospital|Boston Children's Hospital|Harvard University
developmental dyslexia dd learning disability affecting 517 children although researchers agree dd characterized deficient phonological processing pp cause debated suggested altered rapid auditory processing rap may lead deficient pp dd studies shown deficient rap individuals dd functional neuroimaging fmri studies implicated hypoactivations left prefrontal brain regions rap individuals dd neuronal alterations evolve remains unknown article investigate functional networks rap 28 children n 14 without n 14 familial risk dd reading onset mean 56 years results reveal functional alterations lefthemispheric prefrontal regions rap prereading children risk dd similar findings individuals dd furthermore activation rap left prefrontal regions positively correlates prereading measures pp neuronal activation pp posterior dorsal ventral brain areas results suggest neuronal differences rap predate reading instruction thus due experiencedependent brain changes resulting dd functional relationship neuronal networks rap pp within prereading brain