Parul Christian|Laura E. Murray?Kolb|James M. Tielsch|Joanne Katz|Steven C. LeClerq|Subarna K. Khatry
Associations between preterm birth, small-for-gestational age, and neonatal morbidity and cognitive function among school-age children in Nepal
Johns Hopkins University|Pennsylvania State University|Johns Hopkins University|Johns Hopkins University|Johns Hopkins University
long term consequences low birth weight lbw preterm birth smallforgestational age sga defined birth weight given gestational age less 10th percentile reference early newborn morbidity functional outcomes well described low income settingsin rural nepal conducted neurocognitive assessment children n 1927 79 age birth condition exposures available followup tested aspects intellectual executive motor functionthe prevalence lbw 396 preterm birth 212 sga 554 high whereas symptoms birth asphyxia sepsis reported 67 91 children multivariable regression analyses adjusted confounders lbw strongly associated scores universal nonverbal intelligence test unit tests executive function movement assessment battery children mabc preterm associated test scores conversely sga significantly p 0005 associated lower unit scores 204 se 039 higher proportion failure stroop test 006 se 002 lower scores backward digit span test 016 se 004 mabc 098 se 025 finger tapping test 066 se 022 adjusting confounders head circumference birth strongly significantly associated test scores neither birth asphyxia sepsis symptoms significantly associated scores cognitive motor testsin rural south asian setting intrauterine growth restriction high may negative impact long term cognitive executive motor function