Yi-Chia Wei, Yi-Chia Kung, Ching-Po Lin, Chih-Ken Chen, Chemin Lin, Rung-Yu Tseng, Yao-Liang Chen, Wen-Yi Huang, Pin-Yuan Chen, Shin-Tai Chong, Yu-Chiau Shyu, Wei-Chou Chang, Chun-Hung Yeh
White matter alterations and their associations with biomarkers and behavior in subjective cognitive decline individuals: a fixel-based analysis
Behavioral and brain functions : BBF
inferential confusion hypothesis postulates obsessive doubt perpetuated subjective form reasoning characterized primarily distrust reality overreliance imagined possibilities however experimental evidence hypothesis may compromised potential confound type information reality vs possibility valence danger vs safety present study aimed untangle potential confound forty ocd 40 nonclinical participants underwent two versions inferential processes task aardema f et al 2009 quantification doubt obsessivecompulsive disorder international journal cognitive therapy 2 188205 original version realitybased information congruent safety hypothesis whereas possibilitybased information congruent danger hypothesis modified version incorporated present study realitybased information congruent danger hypothesis whereas possibilitybased information congruent safety hypothesis findings support inferential confusion hypothesis ocd control participants changed estimations probability unwanted events based type information received whether conveyed danger safety regardless whether framed reality possibility design present study lend examining alternative explanations persistence doubt ocd hypothesized inferential confusion ocd requires validation particularly important demonstrate findings reflect prudential reasoning strategy