Vicki S. Conn|Maithe Enriquez|Todd Ruppar|Keith C. C. Chan
Meta-analyses of Theory Use in Medication Adherence Intervention Research
University of Missouri|University of Missouri|University of Missouri|University of Missouri
systematic review applied metaanalytic procedures integrate primary research examined theory modellinked medication adherence interventionsextensive literature searching strategies used locate trials testing interventions medication adherence behavior outcomes measured electronic event monitoring pharmacy refills pill counts selfreports randomeffects model analysis used calculate standardized mean difference effect sizes medication adherence outcomescodable data extracted 146 comparisons 19348 participants common theories models social cognitive theory motivational interviewing overall weighted effect size interventions comparing treatment control participants 0294 effect size interventions based singletheories 0323 multipletheory interventions 0214 effect sizes individual theories models ranged 0041 0447 largest effect sizes interventions based health belief model 0477 adult learning theory 0443 smallest effect sizes interventions based precede 0041 selfregulation 0118these findings suggest theory modellinked interventions significant modest effect medication adherence outcomes