Jelena Blanuša, Sunčica Zdravković
Horizontal-vertical illusion in mental imagery: quantitative evidence
Frontiers in human neuroscience
proposed two main phenotypes hidradenitis suppurativa hs exist proposal based upon different elementary structures detected skin namely follicular subtypes inflammatory subtypes accurate definition two variants could help us better identify patients may require early intervention currently approved targeted immunomodulatory therapies define distinguish epidemiological clinical analytic characteristics two hs phenotypes observational descriptive nonrandomized prospective study conducted patients diagnosed hs may 2012 april 2017 specialized unit included ultrasound evaluation performed cases 197 patients included 100 women 97 men aged 25 47 years mean age onset significantly different phenotypes ranging 2669 905 inflammatory subtype 1762 642 follicular subtype follicular subtype patients exhibited significantly higher number nodules combined presence multiple commedons 565 338 versus 089 272 contrasted higher count abscesses fistulas detected inflammatory subtype respectively 4 274 311 256 versus 056 102 026 056 iga levels significantly higher inflammatory subtype 49771 26226 versus 23238 8406 mean ihs4 score evaluation higher inflammatory subtype 2104 119 compared follicular phenotype 754 466 inflammatory subtype found independent risk factor disease aggressiveness multivariate analysis 0034 95 ci 00150072 small sample size preliminary data suggest existence inflammatory hs phenotype associated higher aggressiveness major risk progression natural history disease