Dins Sumerags, Nityanand Jain, Mara Pilmane, Gunta Sumeraga
Assessment of professional singers using laryngeal, respiratory, and airflow measurements
Logopedics, phoniatrics, vocology
many human skin diseases result complex interplay genetic environmental mechanisms largely unknown gwass yielded insight genetic aspect complex disease highlighting regions genome specific genetic variants associated disease leveraging information identify causal genes cell types provide insight fundamental biology inform diagnostics aid drug discovery however etiological mechanisms genetic variant disease still unestablished cases exists unprecedented wealth data computational methods variant interpretation functional context challenging decide start owing lack consensus best way identify causal genetic mechanisms article highlights 3 key aspects genetic variant interpretation prioritizing causal genes cell types pathways provide practical overview main methods datasets giving examples recent atopic dermatitis studies provide blueprint variant interpretation collection resources including brief description links packages web tools provided researchers looking start silico followup genetic analysis associated genetic variants