Clara Blanchard, Flore Laforest, Hélène Vaillant-Roussel, Rémy Boussageon
A REB-reading of cholinesterase inhibitors' effect on all-cause mortality in patients with dementia
Journal of clinical epidemiology
evidence regarding relationship fasting blood glucose fbg suicide attempts sa patients major depressive disorder mdd limited therefore objective research investigate whether fbg independently related sa chinese patients firstepisode drugnave fedn mdd adjusting covariates present study crosssectional study total 1718 participants average age 349 124 years 658 females fedn mdd involved hospital china september 2016 december 2018 multiple logistic regression analysis smooth curve fitting used estimate association fbg risk sa threshold effect examined twopiecewise linear regression model interaction stratified analyses conducted according sex education marital status comorbid anxiety psychotic symptoms prevalence sa patients fedn mdd 201 result fully adjusted binary logistic regression showed fbg positively associated risk sa odds ratio 162 95 ci 113232 smoothing plots also revealed nonlinear relationship fbg sa inflection point fbg 534 mmoll effect sizes confidence intervals left right sides inflection point 053 032088 p 0014 148 104210 p 0030 respectively ushaped relationship fbg sa fedn mdd patients found lowest risk sa fbg 534 mmoll indicating lower higher fbg levels may lead increased risk sa