Son N Tran, Artur S d'Avila Garcez
Deep Logic Networks: Inserting and Extracting Knowledge From Deep Belief Networks
IEEE transactions on neural networks and learning systems
introduction pituitary adenomas pas constitute third common primary intracranial tumours wide prevalence rate 1 40 histologic h e classification acidophilic basophilic chromophobic adenomas little clinical relevance recommended immunohistochemical subclassification therapeutic prognostic significance immunohistochemical subclassification done environment making imperative us evaluate patterns environmentaim determine immunohistochemical patterns pas southeastern nigeriamaterials methods 10year retrospective review pa biopsies received university nigeria teaching hospital enugu memphys hospital neurosurgery enugu grace pathology consults enugu nigeria age sex histologic immunohistochemical subtypes biopsy size diagnosed pas analyzed using statistical package social sciences spss version 20 new york ibm inc results expressed descriptive statisticsresults one hundred cases pas identified study constituting 196 primary intracranial tumors received study centers period review 45 450 females 55 550 males giving female male ratio 112 mean age 453 years commonest histologic type acidophilic adenoma 490 followed basophilic 400 chromophobic 110 adenomas null cell adenomas common immunohistochemical subtype 440 followed prlsecreting adenomas 270 others luteinizing hormone lh 13 130 follicle stimulating hormone fsh 7 70 growth hormone gh 330 tsh 220 acth 110 adenomasconclusion pas predominate amongst males occurring mostly middle age groups southeastern nigeria null cell adenoma commonest immunohistochemical subtype followed prlsecreting adenomas routine immunohistochemical characterization required accurate diagnosis optimal patient care