Tara Donker|Kylie Bennett|Anthony Bennett|Andrew Mackinnon|Annemieke van Straten|Pim Cuijpers|Helen Christensen|Kathleen M Griffiths
Internet-Delivered Interpersonal Psychotherapy Versus Internet-Delivered Cognitive Behavioral Therapy for Adults With Depressive Symptoms: Randomized Controlled Noninferiority Trial
Black Dog Institute|UNSW Sydney|Australian National University|Australian National University|Orygen Youth Health|University of Melbourne|University of Amsterdam|EMGO Institute for Health and Care Research|University of Amsterdam|EMGO Institute for Health and Care Research|Black Dog Institute|UNSW Sydney|Australian National University
facetoface cognitive behavioral therapy cbt interpersonal psychotherapy ipt effective treatments depressive disorders access limited online cbt interventions demonstrated efficacy decreasing depressive symptoms facilitate dissemination therapies among public however efficacy internetdelivered ipt yet unknownthis study examines whether ipt effective noninferior feasible cbt delivered online spontaneous visitors online therapy websitean automated 3arm fully selfguided online noninferiority trial compared 2 new treatments ipt n620 cbt n610 active control treatment moodgym n613 4week period general population outcomes assessed using online selfreport questionnaires center epidemiological studies depression scale cesd client satisfaction questionnaire csq8 completed immediately following treatment posttest 6month followupcompleters analyses showed significant reduction depressive symptoms posttest followup cbt ipt noninferior moodgym withingroup effect sizes medium large groups differences clinical significant change programs reliable change shown posttest followup programs consistently higher rates cbt participants allocated ipt showed significantly lower treatment satisfaction compared cbt moodgym dropout rate 12941843 70 posttest highest moodgym intentiontotreat analyses confirmed findingsdespite high dropout rate lower satisfaction scores study suggests internetdelivered selfguided ipt effective reducing depressive symptoms may noninferior moodgym completion rates ipt cbt higher moodgym indicating progress refining internetbased selfhelp internetdelivered treatment options available people suffering depression include iptinternational standard randomized controlled trial number isrctn 69603913 httpwwwcontrolledtrialscomisrctn69603913 archived webcite httpwwwwebcitationorg6fjmhme1o