Rajesh Sharma
An examination of colorectal cancer burden by socioeconomic status: evidence from GLOBOCAN 2018
Delhi Technological University
colon rectum colorectal cancer cause substantial mortality morbidity worldwide management control complex disease cancer cannot rely old strategy one disease one medicine must make transition newage practices involving predictive preventive personalized medicine pppm core adoption pppm approach cancer management policy level requires quantification cancer burden country level purpose examine burden colorectal cancer 185 countries 2018 based results discuss opportunities presented pppm challenges encountered adopting pppm treatment prevention colorectal cancer age sexwise estimates colorectal cancer procured globocan 2018 country regionwise burden colorectal cancer 185 countries examined using allage agestandardized incidence mortality estimates human development index hdi employed indicator socioeconomic status country mortalitytoincidence ratio mir employed proxy 5year survival rate globally colorectal cancer claimed estimated 880792 lives males 484224 females 396568 185 million new cases males 103 million females 823303 estimated diagnosed 2018 globally agestandardized incidence rate asir 197100000 whereas agestandardized mortality rate asmr recorded 163100000 2018 agestandardized rates highest developed countries led hungary asir 512100000 followed south korea asir 445100000 asmr followed patterns asir highest asmr recorded hungary 215 per 100000 slovakia 204 per 100000 globally mir stood 048 among countries recording 1000 cases nepal registered highest mir 083 lowest recorded south korea 027 agestandardized rates exhibited nonlinear association hdi whereas mir negatively associated hdi colorectal cancer causes substantial burden worldwide exhibit positive association socioeconomic status aid improving screening modalities preventable nature disease due dietary lifestyle risk factors improving treatment procedures burden crc largely curtailed high burden crc developing countries therefore calls effective prevention strategies costeffective screening earlystage detection costeffective predictive personalized treatment regime