Robert P Fellows|Desiree Byrd|Susan Morgello
Effects of information processing speed on learning, memory, and executive functioning in people living with HIV/AIDS
Icahn School of Medicine at Mount Sinai|Icahn School of Medicine at Mount Sinai|Icahn School of Medicine at Mount Sinai
unclear whether degree literacy aging neurologic abnormalities relate cognitive deficits among people living hivaids combined antiretroviral therapy cart era primary aim study simultaneously examine association age hivassociated motor abnormalities major depressive disorder reading level information processing speed learning memory executive functions determine whether processing speed mediated relationships cognitive noncognitive variablesparticipants 186 racially ethnically diverse men women living hivaids underwent comprehensive neurological neuropsychological medical evaluations structural equation modeling utilized assess extent information processing speed mediated relationship age motor abnormalities major depressive disorder reading level cognitive abilitiesage motor dysfunction reading level current major depressive disorder significantly associated information processing speed information processing speed fully mediated effects age learning memory executive functioning partially mediated effect major depressive disorder learning memory effect motor dysfunction learning memory fully mediated processing speedthese findings provide support information processing speed primary deficit may account least part many cognitive abnormalities recognized complex hivaids populations association age information processing speed may account hivaging synergies generation cartera cognitive abnormalities