Jennifer L. Steel|David A. Geller|Kevin H. Kim|Lisa H. Butterfield|Michael B. Spring|Jonathan Grady|Weiing Sun|Wallis Marsh|Michael H. Antoni|Mary Amanda Dew|Vicki S. Helgeson|Richard Schulz|Allan Tsung
<scp>W</scp>eb?based collaborative care intervention to manage cancer?related symptoms in the palliative care setting
University of Pittsburgh|University of Pittsburgh|University of Pittsburgh|UPMC Hillman Cancer Center|University of Pittsburgh|University of Pittsburgh|UPMC Hillman Cancer Center|University of Pittsburgh|Sylvester Comprehensive Cancer Center|University of Miami|University of Pittsburgh|Carnegie Mellon University|University of Pittsburgh|University of Pittsburgh
background aim study examine efficacy collaborative care intervention reducing depression pain fatigue improve quality life methods total 261 patients advanced cancer 179 family caregivers randomized webbased collaborative care intervention enhanced usual care intervention included following 1 web site written audiovisual selfmanagement strategies bulletin board resources 2 visits care coordinator physicians appointment every 2 months 3 telephone followup every 2 weeks primary patient outcomes included measures depression pain fatigue healthrelated quality life secondary outcomes included interleukin il1 il1 il6 il8 levels natural killer nk cell numbers caregiver stress depression results baseline 51 patients reported 1 symptoms clinical range patients presented clinical levels symptoms randomized intervention reductions depression cohens 071 pain cohens 062 fatigue cohens 026 improvements quality life cohens 099 observed compared enhanced usual car arm 6 months reductions il6 018 il1 035 il1 019 il8 015 increases nk cell numbers 023 observed comparison enhanced usual care arm 6 months reductions caregiver stress cohens 075 depression cohens 037 observed 6 months caregivers whose loved ones randomized intervention arm conclusions integration screening symptom management cancer care recommended cancer 2016122127082 2016 american cancer society