Nathália Mota de Faria Gomes|Meire Cardoso da Mota Bastos|Renata Magliano Marins|Aline Alves Barbosa|Luiz Clóvis Parente Soares|Annelise de Oliveira Wilken de Maria Abreu|João Tadeu Damian Souto Filho
Differences between Risk Factors Associated with Tuberculosis Treatment Abandonment and Mortality
Prefeitura Municipal de Campos dos Goytacazes|Prefeitura Municipal de Campos dos Goytacazes|Prefeitura Municipal de Campos dos Goytacazes|Prefeitura Municipal de Campos dos Goytacazes|Prefeitura Municipal de Campos dos Goytacazes|Prefeitura Municipal de Campos dos Goytacazes|Prefeitura Municipal de Campos dos Goytacazes|Instituto Federal Fluminense
objectives identify risk factors associated abandonment treatment mortality tuberculosis tb patients methods study retrospective longitudinal cohort study involving tuberculosis patients treated 2002 2008 tb reference center results total 1257 patients evaluated 691 men 544 40 years age 189 extrapulmonary disease 93 coinfected hiv risk factors associated abandonment treatment included male gender 205 95 ci 115365 nonadherence previous treatment 314 95 ci 196596 addition presence extrapulmonary tb protective factor 033 95 ci 014076 following risk factors associated mortality age 40 years 261 95 ci 176385 coinfection hiv 601 95 ci 378956 illiteracy 188 95 ci 127275 presence severe extrapulmonary tb 233 95 ci 124438 retreatment relapse 195 95 ci 101375 conclusions male gender retreatment abandonment independent risk factors nonadherence tb treatment furthermore age 40 years coinfection hiv illiteracy severe extrapulmonary tb retreatment relapse associated higher tb mortality therefore suggest implementation direct measures control identified risk factors reduce rates treatment failure tbassociated mortality