Pinja Jylänki, Elina Sipinen, Theo Mbay, Arja Sääkslahti, Pirjo Aunio
Combining Numerical Relational and Fundamental Motor Skills to Improve Preschoolers' Early Numeracy: A Pilot Intervention Study
International journal of early childhood = Revue internationale de l'enfance prescolaire = Revista internacional de la infancia pre-escolar
recent years advancements treatment landscape hematological malignancies acute myeloid leukemia acute lymphoblastic leukemia significantly improved disease prognosis overall survival however treatment landscape changing emergence targeted oral therapies immunebased treatments brought forth new challenges evaluating preventing invasive fungal diseases ifds ifd disproportionately affects immunocompromised hosts particularly undergoing therapy acute leukemia allogeneic hematopoietic stem cell transplant review aims provide comprehensive overview pretransplant workup identification prevention ifd patients hematological malignancy pretransplant period offers critical window assess patients risk factors implement appropriate prophylactic measures risk assessment includes evaluation disease host prior treatments environmental factors allowing dynamic evaluation considers disease progression treatment course diagnostic screening involving various biomarkers radiological modalities plays crucial role early detection ifd antifungal prophylaxis choice based available evidence well individual risk assessment potential drugdrug interactions toxicity patient adherence therapeutic drug monitoring ensures effective antifungal stewardship optimal treatment patient education counselling vital minimizing environmental exposures fungal pathogens promoting medication adherence wellstructured individualized approach encompassing risk assessment prophylaxis surveillance patient education essential effectively preventing ifd hematological malignancies ultimately leading improved patient outcomes overall survival