Tiziana Zalla, Nathalie Bouchilloux, Nelly Labruyere, Nicolas Georgieff, Thierry Bougerol, Nicolas Franck
Impairment in event sequencing in disorganised and non-disorganised patients with schizophrenia
Brain research bulletin
people living type 1 diabetes pwt1d increased risk impairments brain function may impact daily life cognitive impairments pwt1d might contribute increasing eating disorders reducing selfmanagement skills deteriorating glycemic control glycemic variability may key determinant disordered eating behaviors well cognitive impairments main objective study better understand impact glycemic variability disordered eating behaviors cognitive impairment consequences selfmanagement skills pwt1d aim recruit 150 pwt1d 50 men women crosssectional study participants record glycemic variability 10day period using continuous glucose monitoring system cgms track dietary intakes using imageassisted food tracking mobile application 2 days four online visits eating behaviors diabetes selfmanagements skills anxiety disorders depression disorder diabetes literacy numeracy skills cognitive flexibility attention deficit level interoception impulsivity behaviors assessed using selfreported questionnaires cognitive functions ie attention executive functions impulsivity inhibition temporal discounting measured finally medical biological sociodemographic data collected understanding pwt1d experience factors impacting glycemic selfmanagement 50 pwt1d also participate qualitative phase protocol consist individual indepth facetoface virtual interviews led trained investigator using semistructured interview study contribute highlighting consequences blood sugar fluctuations ie sugar swings daily life especially disrupt eating behaviors brain functioning better understanding mechanisms involved could eventually allow early detection management problems study also seek understand patients point view allow design appropriate meaningful recommendations clinicaltrialsgov nct05487534 registered 4 august 2022