Saira Mohammed|Elaheh Aghdassi|Irving E. Salit|Ghazal Avand|Morris Sherman|Maha Guindi|Jenny Heathcote|Johane P. Allard
HIV-Positive Patients With Nonalcoholic Fatty Liver Disease Have a Lower Body Mass Index and Are More Physically Active Than HIV-Negative Patients
University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto
determine whether clinical metabolic features associated nonalcoholic fatty liver disease nafld similar hivpositive hivnegative male subjectstwentysix hivpositive 25 hivnegative subjects liver biopsyproven nafld compared liver histology extent steatosis steatosis grading fibrosis staging blood biochemistry glucose insulin cpeptide hemoglobin a1c lipid profile insulin resistance ir using homeostasis model assessment anthropometry body mass index bmi waist circumference arm muscle area dietary intake physical activitythe 2 groups similar age liver histology ir hivpositive patients lower bmi 263 05 vs 302 10 kgm p 0001 lower percentage fat mass 194 09 vs 227 12 p 0026 compared hivnegative patients although caloric intake similar groups hivpositive patients higher physical activity level 83 16 vs 41 08 units exercise per day p 0029 blood triglycerides significantly higher 314 039 vs 186 020 mmoll p 0006 hivpositive patientsalthough nafld similar 2 groups hivpositive patients lower bmi physically active compared hivnegative patients may suggest hiv nafld associated factors related body fatness hiv infection treatment