Cadmon K.P. Lim|Connie Suk?Han Ho|Crystal Hin Ning Chou|Mary Miu Yee Waye
Association of the rs3743205 variant of DYX1C1 with dyslexia in Chinese children
Chinese University of Hong Kong|University of Hong Kong|University of Hong Kong|Chinese University of Hong Kong
dyslexia learning disability characterized difficulties acquisition reading spelling skills independent intelligence motivation schooling studies western populations suggested dyx1c1 candidate gene dyslexia view different languages used caucasian chinese populations therefore worthwhile investigate whether association dyx1c1 chinese children dyslexiaeight single nucleotide polymorphisms snps genotyped three hundred ninety three individuals 131 chinese families two reported literature six tag snps dyx1c1 analysis allelic haplotypic associations performed unphased program multiple testing corrected using false discovery rates replicated previously reported association rs3743205 chinese children dyslexia pcorrected 00072 snp also associated rapid naming phonological memory orthographic skills quantitative trait analysisour findings suggest dyx1c1 associated dyslexia people chinese ethnicity hong kong