Teodoro del Ser|Raquel Barba|Maria M. Morin|J Domingo|Carlos Cemillán|Margarita Pondal|José Vivancos
Evolution of Cognitive Impairment After Stroke and Risk Factors for Delayed Progression
Hospital Universitario Severo Ochoa|Hospital Universitario Severo Ochoa|Hospital Universitario Severo Ochoa|Hospital Universitario Severo Ochoa|Hospital Universitario Severo Ochoa|Hospital Universitario Severo Ochoa|Hospital Universitario Severo Ochoa
cognitive decline occurs approximately 30 stroke patients acute risk factors identified longterm risk examined large samples purpose research determine factors associated progression cognitive impairment strokeconsecutive stroke patients 193 without previous dementia assessed 3 months stroke extensive neuropsychological battery diagnosed according diagnostic statistical manual mental disorders fourth edition criteria clinical dementia rating normal 139 cognitive decline without dementia 18 dementia 18 mild 10 moderate 8 severe 24month followup classified stable progressing improving according change clinical dementia rating score determinants progression cognitive decline ascertained logistic regression analysis clinical neuroimaging complementary datacognitive status 24 months stable cases 151 782 decline progressed 27 14 6 demented 21 nondemented improved 15 78 7 demented 8 nondemented seven nondemented patients became demented 24 months 5 demented became nondemented age odds ratio 105 95 ci 101 11 mental decline stroke 114 95 ci 102 127 number prescribed drugs 134 95 ci 105 172 diastolic blood pressure admission 096 95 ci 093 099 episodes hypotension admission 761 95 ci 111 521 significantly associated cognitive deteriorationcognition rather stable 2 years stroke progression improvement cognitive impairment frequent demented patients age previous cognitive decline polypharmacy hypotension admission risk factors progression