Huda Al-Noumani, Omar Al Omari, Zakariya Al-Naamani
Role of Health Literacy, Social Support, Patient-Physician Relationship, and Health-Related Quality of Life in Predicting Medication Adherence in Cardiovascular Diseases in Oman
Patient preference and adherence
aim study assess impact immunosuppression management coronavirus disease 2019 covid19 outcomes performed singlecenter retrospective study cohort 358 lung transplant recipients ltx period march 2020 april 2022 included symptomatic patients least one positive sarscov2 rtpcr used composite primary outcome covid19 including increased need oxygen since hospital admission icu transfer inhospital mortality assessed univariate multivariate analyses risk factors poor outcomes overall included 91 ltx contracted covid19 covid19 inhospital mortality rate reached 44 hierarchical clustering found strong independent association composite poor outcome discontinuation least one immunosuppressive molecule among tacrolimus cyclosporine mycophenolate mofetil everolimus obesity 16 95ci 196 167 p 001 chronic renal failure 46 95ci 14 18 p 001 also independently associated composite poor outcome conversely full vaccination protective 023 95ci 0046 089 p 0047 administration immunosuppressive drugs tacrolimus cyclocporine everolimus protective effect ltx covid19 probably related intrinsic antiviral capacity