Stefan Đorđević, Mima Stanković, Bojan Jorgić, Saša Milenković, Semrija Smailović, Borko Katanić, Igor Jelaska, Luka Pezelj
The Association of Sagittal Spinal Posture among Elementary School Pupils with Sex and Grade
Children (Basel, Switzerland)
direct infusion mass spectrometry dims growing popularity effective method screening biological samples clinical metabolomics quick execute dims generally requires special skills interpreting results measurements inspecting similarities twodimensional electrospray ionization quadrupole timeofflight esiqtof matrixassisted laser desorptionionization maldi mass spectra pipeline processing qtof mass spectra using opensource packages maldiquant msnbase metaboanalystr tested previously algorithmic workflows relied application software either provided vendor privately developed enthusiasts computationally examined two ways interpreting dims results human blood metabolomic profiling studied spectra acquired using esiqtof maxis impact ii bruker daltonics billerica usa preprocessed using compassdataanalysis commercial software mapped onto metabolites using inlabdeveloped matlab scripts alternatively work used opensource packages maldiquant spectrum preprocessing metaboanalystr data interpretation instead lowavailability commercial homemade tools using set 100 plasma samples 20 volunteers normal body mass index 80 patients different stages obesity observed high degree concordance annotated metabolic pathways proprietary dataanalysismatlab pipeline freely available solution