Pragna Patel|Charles E. Rose|Pamela Y. Collins|Bernardo Nuche?Berenguer|Vikrant V. Sahasrabuddhe|Emmanuel Peprah|Susan Vorkoper|Sonak Pastakia|Dianne M. Rausch|Naomi Levitt
Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries
Center for Global Health|National Center on Birth Defects and Developmental Disabilities|Centers for Disease Control and Prevention|University of Washington|National Institute of Diabetes and Digestive and Kidney Diseases|National Heart Lung and Blood Institute|Fogarty International Center|National Institutes of Health|Purdue University West Lafayette|National Institutes of Health|University of Cape Town
objective appropriately identify treat noncommunicable diseases ncds among persons living hiv plhiv lowandmiddleincome countries lmics imperative understand burden ncds among plhiv lmics current management diseases design systematic review metaanalysis methods examined peerreviewed literature published 1 january 2010 31 december 2016 assess currently available evidence regarding hiv four selected ncds cardiovascular disease cervical cancer depression diabetes lmics focus subsaharan africa databases pubmedmedline cochrane review scopus searched identify relevant literature conditions adequate data available pooled estimates prevalence generated using random fixed effects models results six thousand one hundred fortythree abstracts reviewed 377 potentially relevant prevalence data 141 included summary 57 selected quantitative analysis pooled estimates ncd prevalence hypertension 212 95 ci 163271 hypercholesterolemia 222 95 ci 147321 elevated lowdensity lipoprotein 232 95 ci 152336 hypertriglyceridemia 272 95 ci 207348 low highdensity lipoprotein 523 95 ci 356628 obesity 78 95 ci 43139 depression 244 95 ci 125421 invasive cervical cancer diabetes prevalence 1317 1318 respectively ncdhiv integrated programs screening management approaches contextually appropriate resourcelimited settings exist conclusion improved data collection surveillance ncds among plhiv lmics necessary inform integrated hivncd care models although efforts integrate care exist research needed optimize efficacy programs