Kimberly A. Kaphingst|Colleen M. McBride|Christopher H. Wade|Sharon Hensley Alford|Robert J. Reid|Eric B. Larson|Andreas D. Baxevanis|Lawrence C. Brody
Patients’ understanding of and responses to multiplex genetic susceptibility test results
Washington University in St. Louis|National Human Genome Research Institute|University of Washington Bothell|National Human Genome Research Institute|Henry Ford Hospital|Kaiser Permanente Washington Health Research Institute|Kaiser Permanente Washington Health Research Institute|National Human Genome Research Institute|National Human Genome Research Institute
h2abstracth2h3purposeh3 examination patients responses directtoconsumer genetic susceptibility tests needed inform clinical practice study examined patients recall interpretation responses genetic susceptibility test results provided directly mail h3methodsh3 observational study three prospective assessments testing 10 days receiving results 3 months later participants 199 patients aged 2540 years received free genetic susceptibility testing eight common health conditions h3resultsh3 80 patients correctly recalled results eight health conditions patients unlikely interpret genetic results deterministic health outcomes mean 60 sd 08 scale 17 1 indicating strongly deterministic multivariate analysis patients least deterministic interpretations white ipi 00098 educated ipi 00093 least confused results ipi 0001 1 talked results provider h3conclusionh3 findings suggest patients correctly recall results interpret genetics sole cause diseases subset confused results could benefit consultation healthcare provider could emphasize health habits currently best predictors risk providers could leverage patients interest genetic tests encourage behavior changes reduce disease risk igenet medi advance online publication 5 april 2012