Chris Simon|Michelle Eder|Pauline Raiz|Stephen J. Zyzanski|Rebecca D. Pentz|Eric Kodish
Informed consent for pediatric leukemia research
Rainbow Babies & Children's Hospital|University Hospitals of Cleveland|University Hospitals of Cleveland|Rainbow Babies & Children's Hospital|Rainbow Babies & Children's Hospital|University Hospitals of Cleveland|Rainbow Babies & Children's Hospital|University Hospitals of Cleveland|Rainbow Babies & Children's Hospital|University Hospitals of Cleveland|Rainbow Babies & Children's Hospital|University Hospitals of Cleveland
good fully informed consent critical ethical conduct clinical cancer research authors examined clinician perspectives informed consent pediatric research surveying clinicians five major medical centers routinely enroll patients childrens cancer group studiesbuilding pilot study questionnaire designed elicit clinicians general opinions approaches suggestions related informed consent pediatric leukemia trials questionnaires mailed 132 clinicians eightynine questionnaires returned along 13 nonparticipant forms notifying us clinicians inability participate lack experience pediatric informed consent response rate 75providing information families decide study entry ranked important goal informed consent process whereas parents state shock rated significant obstacle good informed consent clinicians cited high levels parental comprehension key aspects clinical research studies reported information overload increased anxiety effects informed consent process parents several key items associated clinicians gender race professional experience finally one openended question yielded 126 suggestions improve informed consent process grouped 10 meaningful categoriesclinicians report range approaches opinions concerns suggestions improving informed consent process article proposes views suggestions integrated parents patients attempts survey improve informed consent pediatric oncology