Sara A Horne, Chelsea L Sommer, Catherine J Crowley
Evaluating the Impact of a Global Cleft Speech Mentorship Program on Expanding Practitioner Competency in low- and middle-income countries
The Journal of craniofacial surgery
medications unexpected effects disease including harmful drug side effects also beneficial drug repurposing effects disease may result hidden influences drugs disease gene networks discovering biological effects drugs relate disease biology provide insight mechanism latent drug effects help predict new effects develop draphnet model integrates molecular data 429 drugs gene associations nearly 200 common phenotypes learn network explains drug effects disease terms molecular signals present evidence method predict drug effects provide insight biology unexpected drug effects disease using draphnet map drugs known molecular effects downstream effects disease genome put forward disease genes impacted drugs suggest new grouping drugs based shared effects disease genome approach multiple applications including predicting drug uses learning drug biology implications personalized medicine code reproduce analysis available httpsgithubcomrdmelameddrugphenome