Ioannis Zaganas|Panagiotis G. Simos|Maria Basta|Stefania Kapetanaki|Symeon Panagiotakis|Irini Koutentaki|Nikolaos Fountoulakis|Antonios Bertsias|George Duijker|Chariklia Tziraki|Nikolaos Scarmeas|Andreas Plaitakis|Dimitrios T. Boumpas|Christos Lionis|Alexandros N. Vgontzas
The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment
University of Crete|University of Crete|Foundation for Research and Technology Hellas|University of Crete|University of Crete|University of Crete|University of Crete|University of Crete|University of Crete|University of Crete|Eginition Hospital|National and Kapodistrian University of Athens|Icahn School of Medicine at Mount Sinai|National and Kapodistrian University of Athens|University of Crete|University of Crete
aim explore burden dementia cretan aging cohort comprised 3140 persons aged 60 years 568 women 58 33 years formal education 862 living rural areas attended selected primary healthcare facilities island crete greece first study phase formal diagnosis dementia reached 40 participants however selected 505 participants underwent thorough neuropsychiatric evaluation second phase study 344 minimental state examination mmse 24 161 mmse 24 results extrapolated entire cohort prevalence dementia mild cognitive impairment estimated 108 97119 324 308340 respectively using field diagnostic data extrapolated data highest dementia prevalence 272 found 80 84yearold group also showed lowest educational level apparently due lack schooling world war ii