Kaarin J. Anstey|Alex Bahar?Fuchs|Pushpani Herath|Sarang Kim|Richard A. Burns|George W. Rebok|Nicolas Cherbuin
Body brain life: A randomized controlled trial of an online dementia risk reduction intervention in middle?aged adults at risk of Alzheimer's disease
Australian National University|Australian National University|Australian National University|Australian National University|Australian National University|Johns Hopkins University|Australian National University
examine efficacy body brain life bbl 12week online dementia risk reduction interventionbbl evaluated randomized controlled trial 176 middleaged adults 2 risk factors 2 protective factors alzheimers disease ad assessed brief screening instrument participants randomized bbl bbl plus facetoface group sessions bbl ff active control control score australian national universityalzheimers disease risk index anuadri validated index ad risk primary outcome measure assessed baseline 12 26 weeksa group time interaction 26 weeks showed significant reduction anuadri score bbl compared control planned contrasts showed bbl bbl ff groups improvement anuadri scores 12 weeks bbl ff z 025 p 021 bbl z 025 p 008 26 weeks bbl ff z 048 p 001 bbl z 028 p 004 due increase protective factorsthis short intervention resulted dementia risk reduction online dementia risk reduction interventions show promise reducing overall dementia risk middleaged adults multiple risk factorsclinical trial registration study registered trial registration reg actrn12612000147886