Dean G. Cruess|A. Russell Localio|Alec B. Platt|Colleen Brensinger|Jason D. Christie|Robert Gross|Catherine S. Parker|Maureen Price|Joshua P. Metlay|Abigail Cohen|Craig Newcomb|Brian L. Strom|Stephen E. Kimmel
Patient Attitudinal and Behavioral Factors Associated with Warfarin Non-adherence at Outpatient Anticoagulation Clinics
University of Connecticut|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania|University of Pennsylvania
warfarin anticoagulant effective preventing stroke narrow therapeutic range requiring optimal adherence achieve favorable effects goal study examine specific patient factors might help explain warfarin nonadherence outpatient anticoagulation clinics prospective cohort study 156 adults utilized logistic regression analyses examine relationship five treatment prognostics scales millon behavioral medicine diagnostic mbmd well three additional mbmd scales depression future pessimism social isolation daily warfarin nonadherence assessed using electronic medication event monitoring systems caps median 139 days four five treatment prognostic scales greater social isolation associated warfarin nonadherence controlling pertinent demographic medical variables information discomfort scale remained significantly associated warfarin nonadherence time although several factors related warfarin nonadherence patients reporting lack receptivity details regarding medical illness seemed risk warfarin nonadherence information might aid development interventions enhance warfarin adherence perhaps reduce adverse medical events