Nancy R Kressin, Jolie B Wormwood, Tracy A Battaglia, Priscilla J Slanetz, Christine M Gunn
Sociodemographic Variations in Women's Reports of Discussions With Clinicians About Breast Density
JAMA network open
crucial feature life spatial organization compartmentalization molecular cellular tissue levels spatial transcriptomics st technology opened new chapter sequencing revolution emerging rapidly transformative effects across biology technique produces extensive complex sequencing data raising need computational methods comprehensive analysis interpretation developed st browser web tool interactive discovery st images focusing different functional aspects single gene expression expression functional gene sets well inspection spatial patterns cellcell interactions unique feature tool applies selforganizing map som machine learning st data som data portrayal method generates individual gene expression landscapes spot st image enabling downstream analysis high resolution performance spatial browser demonstrated disentangling intratumoral heterogeneity melanoma microarchitecture mouse brain integration machinelearningbased som portrayal interactive st analysis environment opens novel perspectives comprehensive knowledge mining organization interactions cellular ecosystems