Brooks A. Fallis|Irfan A. Dhalla|Jason Klemensberg|Chaim M. Bell
Primary Medication Non-Adherence after Discharge from a General Internal Medicine Service
University of Toronto|University of Toronto|Institute for Clinical Evaluative Sciences|St. Michael's Hospital|St. Michael's Hospital|University of Toronto|Mount Sinai Hospital|Institute for Clinical Evaluative Sciences
medication nonadherence frequently leads suboptimal patient outcomes primary nonadherence occurs patient fill initial prescription particularly important time hospital discharge new medications often prescribed treat illness rather preventionwe studied older adults consecutively discharged general internal medicine service large urban teaching hospital determine prevalence primary nonadherence identify characteristics associated primary nonadherence reviewed electronic prescriptions electronic discharge summaries pharmacy dispensing data april august 2010 drugs listed public formulary primary nonadherence defined failure fill one new prescriptions hospital discharge addition descriptive analyses developed logistical regression model identify patient characteristics associated primary nonadherencethere 493 patients eligible inclusion study 232 prescribed new medications total 66 28 exhibited primary nonadherence 7 days discharge 55 24 30 days discharge examples medications patients nonadherent included antibiotics drugs management coronary artery disease eg betablockers statins heart failure eg betablockers angiotensin converting enzyme inhibitors furosemide stroke eg statins clopidogrel diabetes eg insulin chronic obstructive pulmonary disease eg longacting bronchodilators prednisone discharge nursing home associated increased risk primary nonadherence 225 95 ci 101495primary nonadherence medications newly prescribed hospitalization common likely occur patients discharged nursing home