Jessica Robinson?Papp
Motor Function and Human Immunodeficiency Virus–Associated Cognitive Impairment in a Highly Active Antiretroviral Therapy–Era Cohort
Mount Sinai Medical Center|Emmes (United States)
cognitive impairment long recognized manifestation human immunodeficiency virus hiv infection however highly active antiretroviral therapy haart altered neurologic manifestations hivto develop measure quantify motor abnormalities included original descriptions hivassociated dementia determine whether motor affective behavioral dysfunction predict cognitive impairment determine whether quantitative motor testing helpful adjunct diagnosis complex population haart eraneurologic neuropsychological data collected manhattan hiv brain bank longitudinal cohort study patients advanced hiv hivdementia motor scale hdms developed validated cognitive affective behavioral function quantified using global neuropsychological scores beck depression inventory bdi independent assessment apathy relationships among cognitive motor affective behavioral performance examined using correlation linear regression analyses variancean urban aids research centera total 260 hivpositive predominantly minority patientsthe hdms scores global neuropsychological scoresthe hdms bdi scores independent predictors cognitive impairment significant cognitive impairment found patients motor dysfunction patients diagnosed greater degree motor impairment neurocognitive diagnosesmotor affective behavioral abnormalities predict cognitive impairment hivpositive patients haartera cohort hdms may useful assignment hivassociated neurocognitive impairment hiv populations normative data neuropsychological test design optimal