Claudia R. Albornoz|Evan Matros|Clara N. Lee|Clifford A. Hudis|Andrea L. Pusic|Elena B. Elkin|Peter B. Bach|Peter G. Cordeiro|Monica Morrow
Bilateral Mastectomy versus Breast-Conserving Surgery for Early-Stage Breast Cancer
Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center|Chapel Hill Carrboro City Schools|Zero to Three|Memorial Sloan Kettering Cancer Center
background although breastconserving surgery oncologically safe women earlystage breast cancer mastectomy rates increasing objective study examine role breast reconstruction surgical management unilateral earlystage breast cancer methods retrospective cohort study women diagnosed unilateral earlystage breast cancer 1998 2011 identified national cancer data base conducted rates breastconserving surgery unilateral bilateral mastectomy contralateral prophylactic procedures per 1000 earlystage breast cancer cases measured relation breast reconstruction association breast reconstruction surgical treatment evaluated using multinomial logistic regression controlling patient disease characteristics results total 1856702 patients included mastectomy rates decreased 459 360 per 1000 1998 2005 p 001 increasing 403 per 1000 2011 p 001 mastectomy rates rise 2005 reflects 14 percent annual increase contralateral prophylactic mastectomies p 001 unilateral mastectomy rates change significantly percentage point increase reconstruction rates associated 7 percent increase probability contralateral prophylactic mastectomies greatest variation explained young age32 percent breast reconstruction 29 percent stage 0 5 percent conclusions since 2005 increasing proportion earlystage breast cancer patients chosen mastectomy instead breastconserving surgery trend reflects shift toward bilateral mastectomy contralateral prophylactic procedures may facilitated breast reconstruction availability