Dhyanesh A. Patel|Rohit Sharda|Kristen L. Hovis|Ervin E. Nichols|Nila A Sathe|David F. Penson|Irene D. Feurer|Melissa L McPheeters|Michael F. Vaezi|David O. Francis
Patient-reported outcome measures in dysphagia: a systematic review of instrument development and validation
Vanderbilt University|Vanderbilt University|Vanderbilt University Medical Center
objective patientreported outcome pro measures commonly used capture patient experience dysphagia evaluate treatment effectiveness inappropriate application lead distorted results clinical studies systematic review literature dysphagiarelated pro measures performed 1 identify currently available measures 2 evaluate presence important measurement properties would affect applicability design medline via pubmed interface cumulative index nursing allied health literature health psychosocial instrument database searched using relevant vocabulary terms key terms related pro measures dysphagia three independent investigators performed abstract full text reviews study meeting criteria evaluated using 18item checklist developed priori assessed multiple domains 1 conceptual model 2 content validity 3 reliability 4 construct validity 6 scoring interpretation 7 burden presentation results 4950 abstracts reviewed total 34 dysphagiarelated pro measures publication year 19872014 met criteria extraction analysis several pro measures high quality mads achalasia swalqol ssq oropharyngeal dysphagia promisgi general dysphagia eortcqlqog25 esophageal cancer rompswallowing parkinsons disease dsqeoe eosinophilic esophagitis soal total laryngectomyrelated dysphagia 17 met least one criterion per domain thematic deficiencies current measures evident including 1 direct patient involvement content development 2 empirically justified dimensionality 3 demonstrable responsiveness change 4 plan interpreting missing responses 5 literacy level assessment conclusion first comprehensive systematic review assessing developmental properties available dysphagiarelated pro measures identified several instruments robust measurement properties multiple diseases including achalasia oropharyngeal dysphagia postsurgical dysphagia esophageal cancer dysphagia related neurological diseases findings herein assist clinicians researchers making informed decisions selecting fundamentally sound pro measure given clinical research quality initiative