Ana Alfaro?Acha|Soham Al Snih|M. A. Raji|Yong Fang Kuo|Kyriakos S. Markides|Kenneth J. Ottenbacher
Handgrip Strength and Cognitive Decline in Older Mexican Americans
Complejo Hospitalario Universitario de Toledo|Hospital Virgen del Valle|John Sealy Hospital|The Memory Clinic|John Sealy Hospital|British Geriatrics Society|General Department of Preventive Medicine|The University of Texas Medical Branch at Galveston
cognitive decline dementia associated disability premature death old age examined whether low handgrip strength predicts subsequent cognitive decline older mexican americanswe worked 7year prospective cohort 2160 noninstitutionalized mexican americans aged 65 years older hispanic established population epidemiological study elderly hepese minimental state examination mmse score 21 baseline measures included sociodemographic factors age gender education handgrip strength near distant visual impairment baseline interview ii mmse body mass index bmi medical conditions stroke heart attack diabetes depression hypertension four waves data collectionusing general linear mixed models found significant trend scores lowest quartile handgrip strength baseline associated lower mmse scores time estimate 128 standard error 016 p 0001 significant handgrip strengthbytime interaction mmse scores participants lowest handgrip strength quartile greater cognitive decline time estimate 026 standard error 007 p 001 participants highest quartile association remained statistically significant controlling potential confounding factorsolder mexican americans reduced handgrip strength baseline demonstrated statistically significant decline cognitive function 7year period contrast participants highest handgrip strength quartile maintained higher level cognitive function