Joanne Katz|Anne C C Lee|Naoko Kozuki|Joy E Lawn|Simon Cousens|Hannah Blencowe|Majid Ezzati|Zulfiqar A Bhutta|Tanya Marchant|Barbara Willey|Linda S. Adair|Fernando C. Barros|Abdullah H Baqui|Parul Christian|Wafaie Fawzi|Rogelio González|Jean H. Humphrey|Lieven Huybregts|Patrick Kolsteren|Aroonsri Mongkolchati|Luke C. Mullany|Richard Ndyomugyenyi|Jyh Kae Nien|David Osrin|Dominique Roberfroid|Ayesha Sania|Christentze Schmiegelow|Mariângela Freitas da Silveira|James M. Tielsch|Anjana Vaidya|Sithembiso Velaphi|Cesar G Victora|Deborah Watson?Jones|Robert E. Black
Mortality risk in preterm and small-for-gestational-age infants in low-income and middle-income countries: a pooled country analysis
Johns Hopkins University|Brigham and Women's Hospital|Johns Hopkins University|Johns Hopkins University|London School of Hygiene & Tropical Medicine|Save the Children|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|Imperial College London|Aga Khan University|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|North Carolina Division of Public Health|Universidade Católica de Pelotas|Universidade Federal de Pelotas|Johns Hopkins University|Johns Hopkins University|Harvard University|Harvard Global Health Institute|Pontificia Universidad Católica de Chile|Clinica Santa Maria|Johns Hopkins University|Zvitambo Institute for Maternal and Child Health Research|Instituut voor Tropische Geneeskunde|Ghent University|Instituut voor Tropische Geneeskunde|Ghent University|Mahidol University|Johns Hopkins University|Ministry of Health|Universidad de Los Andes, Chile|Clínica Dávila|University College London|Instituut voor Tropische Geneeskunde|Harvard University|University of Copenhagen|Copenhagen University Hospital|Universidade Federal de Pelotas|George Washington University|Johns Hopkins University|University College London|Chris Hani Baragwanath Hospital|Universidade Federal de Pelotas|London School of Hygiene & Tropical Medicine|Mwanza Intervention Trials Unit|Johns Hopkins University
background babies low birthweight 2500 g increased risk early mortality however low birthweight includes babies born preterm fetal growth restriction infants birthweight less 2500 g estimated neonatal infant mortality associated two characteristics lowincome middleincome countries methods pooled analysis searched available studies identified 20 cohorts providing data 2 015 019 livebirths asia africa latin america recorded data birthweight gestational age vital statistics 28 days life study dates ranged 1982 2010 calculated relative risks rr risk differences rd mortality associated preterm birth 32 weeks 32 weeks 34 weeks 34 weeks 37 weeks smallforgestationalage sga babies birthweight lowest third percentile third tenth percentile us reference population preterm sga combinations findings pooled overall rrs preterm 682 95 ci 3561307 neonatal mortality 250 148422 postneonatal mortality pooled rrs babies sga birthweight lowest tenth percentile reference population 183 95 ci 134250 neonatal mortality 190 132273 postneonatal mortality neonatal mortality risk babies preterm sga higher babies either characteristic alone 1542 9112612 interpretation many babies lowincome middleincome countries sga preterm birth affects smaller number neonates sga associated higher mortality risk mortality risks associated characteristics extend beyond neonatal period differentiation burden risk babies born preterm sga rather low birthweight could guide prevention management strategies speed progress towards millennium development goal 4the reduction child mortality funding bill melinda gates foundation