Dan Pugh|Peter J. Gallacher|Neeraj Dhaun
Management of Hypertension in Chronic Kidney Disease
The Queen's Medical Research Institute|University of Edinburgh|The Queen's Medical Research Institute|University of Edinburgh|The Queen's Medical Research Institute|University of Edinburgh
abstract chronic kidney disease ckd increasingly prevalent condition globally strongly associated incident cardiovascular disease cvd hypertension cause effect ckd affects vast majority ckd patients control hypertension important ckd leads slowing disease progression well reduced cvd risk existing guidelines offer consensus optimal blood pressure bp targets therefore understanding evidence used create guidelines vital considering best manage individual patients nonpharmacological interventions useful reducing bp ckd rarely sufficient control bp adequately patients ckd hypertension often require combination antihypertensive medications achieve target bp certain pharmacological therapies provide additional bpindependent renoprotective andor cardioprotective action must considered instituting therapy managing hypertension context haemodialysis following kidney transplantation presents challenges novel therapies may enhance treatment near future importantly personalised evidencebased management plan remains key achieving bp targets reducing cvd risk slowing progression ckd