Randall M Lou-Meda, Ana Lucía Valle, Carlos Urla, Jacobo Mazariegos
Epidemiologic and socioeconomic profile of Guatemalan hemodialysis patients: Assessment and dissemination via a free-access information system
Clinical nephrology
risk assessment bees mainly based data honey bees however risk assessment intended protect bee species raises question whether data honey bees good proxy bee species issue new resulted several publications sensitivity bee species compared based values 48h median lethal dose ld50 acute test results approach used observed differences sensitivity may result differences kinetics inherent differences species sensitivity addition physiology bee like overall size size honey stomach acute oral tests physical appearance acute contact tests also influences sensitivity bee recently introduced toxicokinetictoxicodynamic tktd model developed interpretation honey bee tests bee general uniform threshold model survival beeguts could integrate results acute oral tests acute contact tests chronic tests within one consistent framework show beeguts model calibrated validated bee species also honey bee among sensitive bee species addition found differences sensitivity species smaller previously published comparisons based 48h ld50 values timedependency ld50 specifics bee physiology main causes wider variation found published literature environ toxicol chem 202400111 2024 authors environmental toxicology chemistry published wiley periodicals llc behalf setac