Aiping Liu, J Z Alex Cheong, Sameeha Hassan, Matthew B Wielgat, Jennifer J Meudt, Elizabeth Catherine Townsend, Dhanansayan Shanmuganayagam, Lindsay R Kalan, Angela Gibson
The effect of anatomic location on porcine models of burn injury and wound healing
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
executive function umbrella term used describe goaldirected regulation thoughts actions emotions important dimension implicated neurodiversity established malleable predictor multiple adult outcomes neurodevelopmental differences linked executive function strengths weaknesses evidence associations specific profiles executive function specific neurodevelopmental conditions mixed exploratory study adopt unsupervised machine learning approach selforganising maps combined kmeans clustering identify datadriven profiles executive function transdiagnostic sample 566 neurodivergent children aged 818 years old include measures designed capture two distinct aspects executive function performancebased tasks designed tap statelike efficiency cognitive skills optimal conditions behaviour ratings suited capturing traitlike application cognitive control everyday contexts three profiles executive function identified one consistent difficulties across types assessments two inconsistent profiles predominantly rating predominantly taskbased difficulties girls children without formal diagnosis likely inconsistent profile primarily taskbased difficulties children different profiles differences academic achievement mental health outcomes could differentiated comparison group children shared profileunique patterns neural white matter organisation importantly childrens executive function profiles directly related diagnostic categories dimensions neurodiversity associated specific diagnoses eg hyperactivity inattention social communication findings support idea two types executive function assessments provide nonredundant information related childrens neurodevelopmental differences used interchangeably findings advance understanding executive function profiles relationship behavioural outcomes neural variation neurodivergent populations