Fatemeh Aliakbari, Elahe Tavassoli, Forouzan Mohammad Alipour, Morteza Sedehi
Promoting Health Literacy and Perceived Self-Efficacy in People with Chronic Obstructive Pulmonary Disease
Iranian journal of nursing and midwifery research
recently undertaken multicenter randomized controlled trial rct treatment booking gestational diabetes mellitus tobogm 20172022 found diagnosis treatment pregnant women early gestational diabetes mellitus gdm improved pregnancy outcomes based data trial study aimed assess costeffectiveness diagnosis treatment early gdm 20 weeks among women risk factors hyperglycemia pregnancy compared usual care treatment 2428 weeks healthcare perspective participants healthcare resource utilization data collected selfreported questionnaires hospital records valued using unit costs obtained standard australian national sources costs reported us dollars using purchasing power parity ppp estimates facilitate comparison costs across countries intentiontotreat itt principle followed missing cost data replaced using multiple imputations bootstrapping method used estimate uncertainty around mean cost difference costeffectiveness results bootstrapped costeffect pairs used plot costeffectiveness ce plane costeffectiveness acceptability curve ceac diagnosis treatment early gdm effective tended less costly ie dominant costsaving 56 composite adverse pregnancy outcome 95 ci 101 12 1373 95 ci 3749 642 compared usual care findings confirmed ce plane 88 bootstrapped costeffect pairs fall southwest quadrant ceac probability intervention costeffective ranged 84 willingnesstopay wtp threshold value 1000099 wtp threshold value 100000 per composite adverse pregnancy outcome prevented subgroup analyses demonstrated diagnosis treatment early gdm among women higher glycemic range fasting blood glucose 95109 mgdl 5360 mmoll 1h blood glucose 191 mgdl 106 mmoll andor 2h blood glucose 162199 mgdl 90110 mmoll effective less costly dominant 78 composite adverse pregnancy outcome 95 ci 146 09 2795 95 ci 6638 533 intervention effective tended less costly 89 composite adverse pregnancy outcome 95 ci 151 26 5548 95 ci 16740 1547 among women diagnosed 14 weeks gestation well findings highlight potential health economic benefits diagnosis treatment early gdm among women risk factors hyperglycemia pregnancy supports implementation longterm followup studies recommended key future area research assess potential longterm health benefits economic consequences intervention national health medical research council grants 1104231 2009326 region orebro research committee grants dnr oll970566 oll942177 medical scientific fund mayor vienna project 15205 project 23026 south western sydney local health district academic unit grant 2016 western sydney university ainsworth trust grant 2019