Jolijn Vanderauwera|Johan Wouters|Maaike Vandermosten|Pol Ghesquière
Early dynamics of white matter deficits in children developing dyslexia
KU Leuven|KU Leuven|KU Leuven|KU Leuven
neural anomalies demonstrated dyslexia recent studies prereaders risk dyslexia prereaders developing poor reading suggest anomalies might cause reading impairment study goes one step exploring neurodevelopmental trajectory white matter anomalies prereaders without familial risk dyslexia n61 strictly selected sample develops dyslexia later n15 collected longitudinal diffusion mri behavioural data grade 3 results provide evidence children dyslexia exhibit prereading white matter anomalies left right long segment arcuate fasciculus af predictive power left segment traditional cognitive measures familial risk whereas white matter differences left af seem strongly related development dyslexia differences left ifof right af seem driven familial risk later reading ability moreover differences left af appeared dynamic study supports expands recent insights neural basis dyslexia pointing towards prereading anomalies related dyslexia well underpinning dynamic character white matter