Md. Rafiqul Islam|Ismail Khan|Sheikh Md Nazmul Hassan|Mark McEvoy|Catherine D’Este|John Attia|Roseanne Peel|Munira Sultana|Shahnaz Akter|Abul Hasnat Milton
Association between type 2 diabetes and chronic arsenic exposure in drinking water: A cross sectional study in Bangladesh
University of Newcastle Australia|Dhaka Medical College and Hospital|Atish Dipankar University of Science and Technology|University of Newcastle Australia|University of Newcastle Australia|University of Newcastle Australia|University of Newcastle Australia|Institute of Child and Mother Health|University of Newcastle Australia
chronic exposure high level inorganic arsenic drinking water associated type 2 diabetes t2d research ecological nature focused high levels arsenic exposure studies directly measuring arsenic levels drinking water index arsenic exposure effect low moderate levels arsenic exposure diabetes risk largely unknown thus study adding knowledge previous worksthis cross sectional study conducted 1004 consenting women men 1682 eligible participants yielding participation rate 60 participants aged 30 years living bangladesh continuously consumed arseniccontaminated drinking water least 6 months t2d cases diagnosed using glucometer following new diagnostic criteria fasting blood glucose 126 mgdl guideline 2006 selfreported physician diagnosis type 2 diabetes association t2d chronic arsenic exposure estimated multiple logistic regression adjustment age sex education body mass index bmi family history t2da total 1004 individuals participated study prevalence t2d 9 95 ci 711 adjustment diabetes risk factors increased risk type 2 diabetes observed arsenic exposure 50 gl highest category almost double risk type 2 diabetes or19 95 ci 1135 levels arsenic exposure risk estimates higher longer exposure doseresponse pattern also observedthese findings suggest association chronic arsenic exposure drinking water t2d risks generally higher longer duration arsenic exposure risk t2d highest among exposed highest concentration arsenic 10 years