Hilary Davies?Kershaw|Ruth A. Hackett|Dorina Cadar|Annie Herbert|Martin Orrell|Andrew Steptoe
Vision Impairment and Risk of Dementia: Findings from the English Longitudinal Study of Ageing
University College London|University of Surrey|University College London|University College London|University College London|University of Surrey|Institute of Mental Health|University of Nottingham|University College London
determine whether vision impairment independently associated crosssectionally longitudinally dementiaretrospective cohort studyenglish longitudinal study ageingindividuals aged 50 older measurements crosssectional association selfrated vision poor blind moderate normal dementia analyzed adjusting potential confounders sex wealth education cardiovascular risk factors using multivariable logistic regression also modelled adjusted longitudinal association vision impairment dementia average 11 years followup using cox proportional hazards regression individuals aged 50 69 aged 70 olderafter adjustment confounders participants rated vision moderate 20 95 confidence interval ci1431 times likely normal vision dementia rated vision poor 40 95 ci2661 times likely longitudinally individuals aged 50 69 rated vision moderate 18 95 ci1030 poor 36 95 ci11118 greater risk developing dementia rated vision normal significant difference risk aged 70 olderour study confirms extends findings countries demonstrating crosssectional associations moderate poor selfrated vision dementia england participants aged 50 older longitudinally 11year period aged 50 69 results help establish vision loss risk factor dementia although unclear research needed determine whether screening treatment vision loss may slow cognitive decline