George J. Wan|Michael A. Counte|David Cella|Lorena Acosta Hernández|S Deasy|Gail Shiomoto
An Analysis of the Impact of Demographic, Clinical, and Social Factors on Health-Related Quality of Life
study investigated impact demographic social clinical factors cancer patients selfratings healthrelated quality life hrql sample consisted 1342 ethnically diverse individuals treatment four member institutions eastern cooperative oncology group ecog multivariable regression analyses employed determine relationship demographic variables age gender raceethnicity socioeconomic status ses living arrangement clinical factors performance status rating psr disease type disease stage social characteristics spiritual beliefs religious affiliation relationship physician five outcome measures hrql dependent variables four dimensions hrql overall hrql measured functional assessment cancer therapygeneral factg quality life measurement system results indicated full set predictor variables accounted 45 variance patients reporting overall hrql 25 variance physical wellbeing 27 variance social wellbeing 30 variance emotional wellbeing 41 variance area functional wellbeing findings suggest multiple factors influence individuals assessment hrql factors need considered management treatment culturally diverse cancer patients