Maristella Scorza, Samuel T Gontkovsky, Marta Puddu, Angela Ciaramidaro, Cristiano Termine, Loriana Simeoni, Marcella Mauro, Erika Benassi
Cognitive Profile Discrepancies among Typical University Students and Those with Dyslexia and Mixed-Type Learning Disorder
Journal of clinical medicine
mathematical ability moderately heritable complex trait evaluated several different categories genetic studies published general mathematical ability however genetic study focused specific mathematical ability categories study separately performed genomewide association studies 11 mathematical ability categories 1146 students chinese elementary schools identified seven genomewide significant single nucleotide polymorphisms snps strong linkage disequilibrium among r2 08 associated mathematical reasoning ability top snp rs34034296 p 201 108 nearest gene cub sushi multiple domains 3 csmd3 replicated one snp rs133885 585 snps previously reported associated general mathematical ability associated division ability data p 1053 105 gene geneset enrichment analysis magma found three significant enrichments associations three mathematical ability categories three genes lingo2 oas1 hectd1 also observed four significant enrichments associations four mathematical ability categories three gene sets results suggest new candidate genetic loci genetics mathematical ability