Isadora Siqueira de Souza, Francisco Timbó de Paiva Neto, Rebecca Cabral de Figueirêdo Gomes Pereira, Guilherme Barbosa Shimocomaqui, Ana Cláudia Pereira da Paz, Marcio Anderson Cardozo Paresque, Ilana Eshriqui
Characterization of teaching-learning tutors in public health services and topics of interest for their work
Revista da Escola de Enfermagem da U S P
hepatitis e virus hev genotype 3 major cause acute viral hepatitis several european countries acquired mainly ingesting contaminated pork also reported transmitted blood transfusion although hev infections including via blood products usually selflimiting may become chronic immunocompromised persons thus essential identify hevinfected blood donations prevent transmission vulnerable recipients prior decision whether introduce hev rna screening swiss blood donations 2year nationwide prevalence study conducted blood donations screened pools 1224 samples five regional blood donation services hev rnapositive pools subsequently resolved individual donation index donation x viral load hev igg igm serology hev genotype determined followup investigations conducted future control donations x 1 previous archived donations donor x 1 available october 2018 september 2020 541349 blood donations screened 125 confirmed positive donations identified prevalence 14331 donations time blood donation hev rnapositive individuals symptomfree median viral load 554 iuml range 2012500000 iuml men 88 70 frequently infected women 37 30 compared sex distribution swiss donor population 57 male43 female p 001 106 genotyped cases 85 belonged genotype 3 two hev subgenotypes predominated 3h3 formerly 3s 3c remaining subgenotypes known circulate europe five 3ra genotypes identified variant associated rabbits total 85 68 x donations negative hev igm igg remaining 40 32 positive hev igg andor igm consistent active infection found markers previous hev 87 89 available analyzed archive samples x 1 two donors hev iggpositive x 1 donation suggesting insufficient immunity prevent hev reinfection time collection 90 72 analyzed x 1 donations varied 29 1019 weeks median 35 weeks x donation expected none tested positive hev rna donors 89 99 positive antihev lgglgm ie seroconversion hev lgmpositivity 23 26 indicates oftenlong persistence lgm antibodies posthev infection data collected first year study provided basis decision establish mandatory hev rna universal screening swiss blood donations minipools vital step providing safer blood recipients especially immunosuppressed