Toshiharu Tsutsui, Satoshi Iizuka, Wataru Sakamaki, Toshihiro Maemichi, Suguru Torii
Growth until Peak Height Velocity Occurs Rapidly in Early Maturing Adolescent Boys
Children (Basel, Switzerland)
ribosomal core universally conserved across tree life however eukaryotic ribosomes contain diverse rrna expansion segments ess surfaces sites es insertions predicted sites insertion microess archaea expansion segment 7 es7 one diverse regions ribosome emanating short stem loop ranging 750 nucleotides mammals present secondary fullatom 3d structures es7 species spanning eukaryotic diversity results based experimental 3d structures accretion model ribosomal evolution phylogenetic relationships multiple sequence alignments rna folding algorithms 3d modeling rnacomposer es7 contains distinct motif es7 signature fold generally invariant 2d topology 3d structure eukaryotic ribosomes establish model es7 developed evolution series elementary recursive growth events data sufficient support atomiclevel accretion path rrna growth nonmonophyletic distribution es7 features across phylogeny suggests acquisition via convergent processes finally illustrating power approach constructed 2d 3d structure entire lsu rrna mus musculus