Marina J Muñoz-Rivas, Román Ronzón-Tirado, Juan J López-Ossorio, Natalia Redondo
Beyond the Initial Assault: Characterizing Revictimization in Intimate Partner Violence and Its Implications for Women's Health
Psychosocial intervention
metabolomics plays critical role deciphering metabolic alterations within individuals demanding use sophisticated analytical methodologies navigate intricate complexity many studies focus single biofluid types simultaneous analysis multiple matrices enhances understanding complex biological mechanisms consequently development data fusion methods enabling multiblock analysis becomes essential comprehensive insights metabolic dynamics study introduces novel guideline jointly analyzing diverse metabolomic datasets serum urine metadata focus metabolic differences groups within healthy cohort guideline presents two fusion strategies lowlevel data fusion lldf midlevel data fusion mldf employing sequential application multivariate curve resolution alternating least squares mcrals linking outcomes successive analyses mcrals versatile method analyzing mixed data adaptable various stages data processingencompassing resonance integration data compression exploratory analysis lldf mldf strategies applied 1h nmr spectral data extracted urine serum samples coupled biochemical metadata sourced 145 healthy volunteers methodologies effectively integrated analysed multiblock datasets unveiling inherent data structure variables associated discernible factors among healthy cohorts approaches successfully detected sexrelated differences mldf strategy uniquely revealed components linked age applying analysis aim enhance interpretation intricate biological mechanisms uncover variations may easily discernible individual data analysis