Lan Cheng, W K Chan, Lijie Zhu, Melody H Chao, Yang Wang
Confronting Inequalities and Bridging the Divide: A Retrospective Study Assessment of Country-Level COVID-19 Vaccine Equality with a Cox Regression Model
Vaccines
hypothetical concept macrocyclic cavity largely employed useful model interpret affinity metal ions macrocyclic chelating ligand 222214710tetraazacyclododecane14710tetrayltetraacetic acid h4dota hypothesized close matching size macrocyclic cavity metallic ion key parameter ensure highyield formation stable coordination metaldota complex approach become popular design radiopharmaceuticals containing radiometals h4dota chelating group based xray structural data metallic complexes formed ligand h4dota upon coordination variety metals elementary argument based euclidean geometry presented questions existence hypothetical macrocyclic cavity within chelator macrocycle geometrical analysis applied complex formed ga3 ion coordinated h4dota model compound application euclidean geometry calculate bond angles coordination complex ligand h4dota ga3 ion supposed incorporate hypothetical macrocyclic cavity revealed conceptual entity physical reality therefore cannot considered meaningful description stable structural arrangement metallic radiopharmaceuticals