Marina Serper|Peter P. Reese|Rachel Patzer|Josh Levitsky|Michael S. Wolf
The prevalence, risk factors, and outcomes of medication trade-offs in kidney and liver transplant recipients: a pilot study
University of Pennsylvania|University of Pennsylvania|Emory University|Northwestern University|Northwestern University
high outofpocket medication costs negatively impact adherence transplantation evaluated association medication tradeoffsdefined choosing spend money expenses medicationswith medication nonadherence transplant outcomes 2011 2012 performed prospective study 201 transplanted recipients n 103 liver n 98 kidney two large us transplant centers structured interviews assessed sociodemographics medication adherence medication tradeoffs multivariable models assessing risk factors medications tradeoffs association medications tradeoffs posttransplant hospital admissions performed total 17 patients reported medication tradeoffs common tradeoffs inability afford prescription past 12 months making choices prescriptions food multivariable analysis insurance type rr 297 95 ci 119740 limited health literacy rr 264 95 ci 123564 3 comorbid conditions rr 248 95 ci 109562 p 005 associated tradeoffs patients tradeoffs likely report nonadherence medications mean adherence 77 23 tradeoffs vs 89 19 without tradeoffs p 001 presence medication tradeoffs associated posttransplant hospital admissions rr 164 95 ci 114235 p 001 assessments financial barriers warranted clinical practice identify nonadherence improve posttransplant outcomes