Tom Hähnel, Tamara Raschka, Stefano Sapienza, Jochen Klucken, Enrico Glaab, Jean-Christophe Corvol, Björn H Falkenburger, Holger Fröhlich
Progression subtypes in Parkinson's disease identified by a data-driven multi cohort analysis
NPJ Parkinson's disease
ottawa 3dy o3dy simple measure cognition 1 determine o3dy predicts mortality 2 compare discrimination o3dy minimental state examination mmse modified mmse 3ms analyses population based cohort study 1751 participants aged 65 conducted 19912 followup five years o3dy age sex education comorbid conditions mmse 3ms measured 45 participants missing data o3dy 428 considered positive one errors 527 considered negative errors logistic regression models constructed outcome death time 2 receiver operator curve roc constructed area roc auroc calculated using cstatistic unadjusted odds ratio 95 confidence interval ci mortality 196 156 247 adjusted 133 102 172 auroc 066 3ms 065 mmse 060 o3dy o3dy predicts mortality long time frame although discrimination less longer measures cognition