Leigh M Harrell-Williams, Tara C Raines, Randy W Kamphaus, Bridget V Dever
Psychometric analysis of the BASC-2 Behavioral and Emotional Screening System (BESS) student form: Results from high school student samples
Psychological assessment
toxicology 21st century seen shift chemical risk assessment based traditional animal tests identifying apical endpoints doses safe prospect next generation risk assessment based nonanimal methods increasingly large high throughput vitro datasets generated exploited develop computational models accompanied increased use machine learning approaches model building process potential problem however models robust predictive may still lack credibility perspective enduser commentary argue science causal inference reasoning proposed judea pearl facilitate development use acceptance quantitative aop models hope importing established concepts causality outside field toxicology constructively disruptive current toxicological paradigm using causal revolution bring toxicological revolution rapidly