Anita Elizabeth Pienaar, Carli Gericke, Wilmarié du Plessis
Longitudinal pathways of associations between motor proficiency and physical fitness during earlier and later childhood: The NW-CHILD study
Science progress
head neck cancer hnc often requires treatment major impact quality life treatment decisionmaking often challenging involves balancing survival preservation quality life choosing among treatments comparable outcomes variation morbidity adverse events consequently potential decisional conflict dc decision regret dr high summarize literature dc dr hnc give overview prevalence extent advise clinical practice future research embase web science medline psycinfo searched february 24 2023 including years publication eligible studies addressed dc andor dr primary secondary outcomes instrument hnc except cutaneous tumors two mutually blinded researchers conducted screening inclusion support artificial intelligence assistant conducted risk bias rob assessment preferred reporting items systematic review metaanalyses guidelines followed data extraction rob assessments done using critical appraisal skills programme qualitative clarity quantitative metaanalysis randomeffects model used obtain pooled prevalence estimates dc dr least 4 sufficiently clinically homogeneous studies available prevalence dc qualitative decisional conflict scale sure questionnaire dr qualitative studyspecific questionnaires decision regret scale shame stigma scale overall 28 studies included 16 included metaanalyses dr prevalence pooled prevalence clinically relevant dr cutoff score validated questionnaires 11 studies 2053 participants 71 95 ci 5882 i2 94 studyspecific questionnaires 5 studies 674 participants 11 95 ci 522 i2 92 4 studies investigated dc showing prevalence 226 475 cutoff values derived overarching themes found qualitative studies preparation shared decisionmaking roles information time pressure stress diagnosis consequences although limited data dc dr available studies performed indicated dc dr highly prevalent issues hnc results suggest studyspecific questionnaires underestimated dr findings underscore rationale improve counseling shared decisionmaking patient population