Syed Nazmul Huda|Sally Grantham?McGregor|Khondaker Miraz Rahman|Andrew Tomkins
Biochemical Hypothyroidism Secondary to Iodine Deficiency Is Associated with Poor School Achievement and Cognition in Bangladeshi Children
London International Development Centre|London International Development Centre|University of Dhaka|London International Development Centre
iodine deficiency pregnancy leads poor cognitive function offspring however effect concurrent iodine deficiency schoolaged children clear several studies shown school children iodinedeficient villages poorer cognitive function children iodinesufficient villages however villages differ many factors may also detrimentally affect childrens development addition childrens nutritional health status usually taken account study compared cognitive function school achievement levels 170 children recently low thyroxine t4 levels t4 45 nmoll hypothyroid children low t4 levels t4 70 nmoll euthyroid children matched school grade level came iodinedeficient regions rural bangladesh given battery cognitive motor school achievement tests also measured nutritional status examined stools geohelminths assessed home environments factor analysis cognitive motor function tests yielded two factors general cognitive factor fine motor factor childrens height arm circumference experience hunger parental characteristics stimulation home made independent contributions test scores controlling variables hypothyroid children performed worse euthyroid children reading spelling general cognitive factor findings indicate large number disadvantages including hypothyroidism related poor development children