Eric B. Loucks|Stephen E. Gilman|Chanelle J. Howe|Ichiro Kawachi|Laura D. Kubzansky|Rima E. Rudd|Laurie T. Martin|Arijit Nandi|Aude Wilhelm|Stephen L. Buka
Education and Coronary Heart Disease Risk
Brown University|Providence College|Harvard University|Massachusetts General Hospital|Brown University|Providence College|Harvard University|Harvard University|Harvard University|RAND Corporation|McGill University|Brown University|Providence College|Brown University|Providence College
objective education inversely associated coronary heart disease chd risk however mechanisms poorly understood study objectives evaluate extent rarely measured factors literacy time preference sense control commonly measured factors income depressive symptomatology body mass index educationchd literature explain associations education chd risk method study sample included 346 participants aged 38 47 years 595 women new england family study birth cohort tenyear chd risk calculated using validated framingham risk algorithm utilizes diabetes smoking blood pressure total cholesterol highdensity lipoprotein cholesterol age gender multivariable regression mediation analyses performed results regression analyses adjusting age raceethnicity childhood confounders eg parental socioeconomic status intelligence demonstrated relative greater equal college education men women less high school 737 95 confidence interval ci 295 1330 482 95 ci 175 868 higher 10year chd risk respectively mediation analyses demonstrated significant indirect effects reading comprehension women 72 95 ci 07 194 men 72 95 ci 08 191 depressive symptoms 118 95 ci 25 266 perceived constraint 67 95 ci 07 191 women conclusions evidence suggested reading comprehension women men depressive symptoms perceived constraint women may mediate association education chd risk mediated effects interpreted causally interventions targeting reading depressive symptoms perceived constraint could reduce educational inequalities chd