Shiqin Liao, Jie Li, Mingting Liu, Hongmei Xie, Yutong Lu, Yunlan Jiang
Acceptance and associated factors of HIV testing among college students in China: A systematic review and meta-analysis
PloS one
acute gastroenteritis outbreaks may caused excretion norovirus nov asymptomatic individuals despite numerous studies involving asymptomatic nov infection outbreaks china comprehensive assessment role conducted critical emergency management objective assess prevalence asymptomatic nov infection outbreaks china conducted comprehensive search multiple databases including pubmed web science cochrane library china national knowledge infrastructure china wanfang china weipu january 1 1997 june 19 2023 retrieved articles references underwent screening utilized polymerase chain reactionbased assays detection nov asymptomatic individuals outbreaks occurred china primary summary data prevalence asymptomatic nov infection outbreaks generated pooled estimates asymptomatic prevalence population whole subgroups using randomeffect models 97 articles included pooled asymptomatic prevalence nov among 5117 individuals outbreaks 176 95 confidence interval ci 141213 asymptomatic prevalence nov gii 171 95 ci 129215 similar nov gi 220 95 ci 128324 however proportion asymptomatic individuals involved nov gii 5744 significantly higher nov gi 512 nov gii 7526 reported much frequently nov gi 1443 included articles metaregression analysis 11 possible influencing factors geographic region setting season sample type genotype transmission route occupation age per capita income study quality cases definition showed source heterogeneity might related outbreak settings per capita income study quality p 0037 0058 0026 respectively particular note asymptomatic prevalence peaked preschoolers 278 afterward fell trough elementary junior school children 105 second peak located adults 178 elderly 252 prevalent genotypes reported include gii4 followed gii17 gii2 gii3 gii6 forth estimated asymptomatic prevalence nov outbreaks china high 176 nov gii dominating addition genetic subtypes nov outbreaks detected whenever possible role asymptomatic individuals nov outbreaks cannot ignored knowledge help governments develop public health policies emergency response strategies outbreaks assess burden develop vaccines