Sergey Lytaev
Psychological and Neurophysiological Screening Investigation of the Collective and Personal Stress Resilience
Behavioral sciences (Basel, Switzerland)
given psychosocial burdens patients advanced stages cancer face innovative care concepts needed time vulnerable patient groups difficult reach participation intervention studies randomized patient inclusion may feasible article aims identify systematic biases respectively selection effects occurring recruitment phase discuss potential causes based nonrandomized multicenter intervention study patients advanced stages cancer patients diagnosed least one 16 predefined cancers recruited four hospitals three german cities effect social care nurses continuous involvement acute oncology wards measured healthrelated quality life eortc qlqc30 information participation preferences decisional conflicts doctorpatient communication health literacy symptom perception absolute standardized mean difference calculated standardized effect size test baseline characteristics balance intervention control groups study enrolled 362 patients 150 intervention 212 control group except gender groups differed relevant sociodemographic characteristics eg regarding age educational background respect distribution diagnoses intervention group showed higher symptom burden control group moreover control group reported better quality life baseline compared intervention group 526 points sd 217 478 points sd 220 asmd 0218 p 0044 overall intervention group showed social health vulnerability control group among factors wide range diagnoses included structural variation recruiting clinics increased risk bias recommend close continuous monitoring relevant social healthrelated characteristics recruitment phase well use appropriate statistical analysis strategies adjustment propensity score methods german clinical trials register drksid drks00013640 registered 29th december 2017