J Michael Murphy, Javier Guzmán, Alyssa E McCarthy, Ana María Squicciarini, Myriam George, Katia M Canenguez, Erin C Dunn, Lee Baer, Ariela Simonsohn, Jordan W Smoller, Michael S Jellinek
Mental health predicts better academic outcomes: a longitudinal study of elementary school students in Chile
Child psychiatry and human development
effect blended preconception lifestyle programme reproductive lifestyle outcomes couples going first 12 months ivf compared attention control condition randomized controlled trial rct stopped prematurely coronavirus disease 2019 covid19 pandemic available data suggest blended preconception lifestyle programme could meaningfully affect time ongoing pregnancy reproductive lifestyle outcomes increasing evidence shows associations healthy lifestyle ivf success rates lifestyle programmes provided mobile phone application yet evaluated rcts couples undergoing ivf multicentre rct 11 carried rct started january 2019 prematurely stopped covid19 pandemic leading reduced sample size 211 couples initiating ivf change primary outcome cumulative ongoing pregnancy time ongoing pregnancy heterosexual couples initiating ivf five fertility clinics randomized attention control arm intervention arm 12 months attention control arm received treatment information mobile phone addition standard care intervention arm received blended preconception lifestyle prelifeprogramme addition standard care prelifeprogramme included mobile application offering tailored advice skills training diet physical activity mindfulness combination motivational interviewing telephone primary outcome time ongoing pregnancy secondary reproductive outcomes included core outcome measures infertility trials ivf discontinuation changes following secondary lifestyle outcomes 3 6 months studied partners diet quality fruit intake vegetable intake total moderate vigorous physical activity sedentary behaviour emotional distress quality life bmi waist circumference finally intervention arm acceptability programme evaluated actual use mobile application part programme tracked analysis according intention treat total 211 couples randomized 105 control arm 106 intervention arm hazard ratio intervention time ongoing pregnancy 094 95 ci 063 14 little effect reproductive lifestyle outcomes identified although acceptability programme good 610 considerable proportions men 38 9 women actively use modules mobile application diet physical activity mindfulness findings rct considered exploratory covid19 pandemic limited power actual use mobile application low first multicentre rct evaluating effect blended preconception lifestyle programme women partners undergoing ivf reproductive lifestyle outcomes exploratory rct highlights need studies optimal intervention characteristics actual use preconception lifestyle programmes well rcts evaluating effectiveness supported research foundation flanders belgium fwotbm reference t005417n competing interests declare clinicaltrialsgov identifier nct03790449 31 december 2018 2 january 2019