C T Rexen, A K Ersbøll, N Wedderkopp, L B Andersen
Longitudinal influence of musculo-skeletal injuries and extra physical education on physical fitness in schoolchildren
Scandinavian journal of medicine & science in sports
performed systematic review metaanalysis investigate performance ml detecting genetic mutation status nsclc patients conducted systematic search pubmed cochrane embase web science july 2023 discussed genetic mutation status egfr alk kras braf well mutation status different sites egfr included total 128 original studies 114 constructed ml models based radiomic features mainly extracted ct mri petct data genetic mutation perspective 121 studies focused egfr mutation status analysis validation set detection egfr mutation status aggregated cindex 0760 95ci 07060814 clinical featurebased models 0772 95ci 07530791 ctbased radiomics models 0816 95ci 07760856 mribased radiomics models 0750 95ci 07120789 petctbased radiomics models combined clinical features aggregated cindex 0807 95ci 07810832 ctbased radiomics models 0806 95ci 07730839 mribased radiomics models 0822 95ci 07890854 petctbased radiomics models validation set aggregated cindexes radiomicsbased models detect mutation status alk kras well mutation status different sites egfr greater 07 use radiomicsbased methods early discrimination egfr mutation status nsclc demonstrates relatively high accuracy however influence clinical variables cannot overlooked process addition future studies also pay attention accuracy radiomics identifying mutation status genes egfr