Zachary A. Marcum|Joseph T. Hanlon|Michael D. Murray
Improving Medication Adherence and Health Outcomes in Older Adults: An Evidence-Based Review of Randomized Controlled Trials
University of Washington|Seattle University|Pittsburgh Public Schools|University of Pittsburgh|VA Pittsburgh Healthcare System|Geriatric Research Education and Clinical Center|Regenstrief Institute|Indiana University – Purdue University Indianapolis
poor medication adherence major public health problem older adults often resulting negative health outcomes objective review provide updated summary evidence randomized controlled studies determine whether interventions aimed improving medication adherence also improve health outcomes older adults residing communitybased settings articles assessed medication adherence interventions related health outcomes elderly individuals identified searches medline 1970june 2016 cochrane database systematic reviews june 2016 google scholar across 12 included studies interventions grouped three main categories behavioraleducational n 3 pharmacistled n 7 remindersimplification n 2 among behavioraleducational intervention studies two showed improvements adherence related health outcomes whereas one found changes adherence health outcomes among pharmacistled studies three showed improvements adherence related health outcomes three reported changes adherence health outcomes one found improvement adherence health outcomes among remindersimplification studies studies reported improvements adherence without significant impact related health outcomes evidencebased review medication adherence interventions older adults revealed promising strategies larger context largely mixed body literature future patientcentered multidisciplinary interventions developed tested using evidencebased principles improve medication adherence health outcomes older adults