Angela Smith|Byron C. Jaeger|Laura C. Pinheiro|Lloyd J. Edwards|Hung?Jui Tan|Matthew E. Nielsen|Bryce B. Reeve
Impact of bladder cancer on health?related quality of life
University of North Carolina Health Care|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of North Carolina Health Care|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill
identify changes healthrelated quality life hrqol diagnosis bladder cancer older adults comparison group adults without bladder cancer controlsdata surveillance epidemiology end results registries linked medicare health outcomes survey mhos data medicare beneficiaries aged 65 years period 19982013 diagnosed bladder cancer baseline followup mhos matched control subjects without cancer using propensity scores linear mixed models used estimate predictors hrqol changesafter matching 535 patients bladder cancer 458 nonmuscleinvasive bladder cancer nmibc 77 muscleinvasive bladder cancer mibc 2 770 control subjects without cancer identified patients nmibc mibc reported significant declines hrqol scores time vs controls physical component summary 2 53 vs 04 respectively bodily pain 19 36 vs 07 role physical 27 47 vs 07 general health 24 61 vs 0 vitality 12 35 vs 01 social functioning 21 57 vs 08 scores ranged 0 100 stratified time since diagnosis hrqol improved 1 year domains role physical remained lower across domainsafter diagnosis patients bladder cancer experienced significant declines physical mental social hrqol relative controls decrements pronounced among individuals mibc methods better understand address hrqol decrements among patients bladder cancer needed