Roberta Bevilacqua, Vera Stara, Giulio Amabili, Arianna Margaritini, Marco Benadduci, Federico Barbarossa, Elvira Maranesi, Anne-Sophie Rigaud, Sébastien Dacunha, Cecilia Palmier, Johanna Moller, Ryan Browne, Toshimi Ogawa, Rainer Wieching
e-VITA study protocol: EU-Japan virtual coach for smart aging
Frontiers in public health
antimicrobial resistance amr decreases effectiveness antimicrobials treat bacterial infections humans animals increased occurrence amr bacterial population humans animals environment requires measures combat rising global health crisis aim research present current knowledge amr system map identify potential explanations former identified variables significantly associated amr study applies systems thinking approach uses feedback loops visualize interconnections human animal environmental components circular amr system map model first literature review focusing amr socioeconomic factors wicked problem system change carried processed system map conceptualize present core challenges amr via feedback loops second investigate possible underlying values society influence humans behavior present amr system iceberg model established third leverage points assessed estimate kinds interventions would greatest effect mitigate amr system present amr system map implies potential identify visualize important risk factors direct indirect drivers amr results show tool system mapping interconnects animals humans environment one model approach amr holistically used assess potential powerful entry points system wide interventions study shows system maps beneficial model predict relative effect different interventions adapt rapidly changing environments complex world systems thinking considered complementing approach statistical thinking research needed evaluate use tools development monitoring interventions