Satish Melwani, Verity Cleland, Kira Patterson, Rosie Nash
Health literacy profiles of pregnant women and mothers in Tasmania: A cluster analysis
Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals
colorectal cancer guidelines recommend screening colonoscopy every 10 years negative procedure risk reduction extends past 10 years recommended interval could extended reducing burden individual healthcare system aimed estimate duration patients remain reduced risk colorectal cancer incidence mortality complete colonoscopy populationbased cohort study individuals aged 5065 years jan 1 1994 dec 31 2017 excluded individuals previous exposure colonoscopy colorectal surgery previously diagnosed colorectal cancer history hereditary bowel disorders followed participants dec 31 2018 identified colonoscopies performed time period used 9level timevarying measure exposure capturing time since last complete colonoscopy complete colonoscopy 5 years 510 years 1015 years 15 years whether intervention performed biopsy polypectomy cox proportional hazards regression model adjusting age sex comorbidity residential income quintile immigration status used estimate association exposure complete colonoscopy colorectal cancer incidence mortality 5 298 033 individuals 2 609 060 492 female 2 688 973 508 male data ethnicity available included cohort median followup 1256 years iqr 6262013 90 532 17 individuals diagnosed colorectal cancer 44 088 08 died colorectal cancer compared colonoscopy risk colorectal cancer complete negative colonoscopy reduced timepoints including procedure occurred 15 years earlier hazard ratio hr 062 95 ci 051077 female individuals 057 046070 male individuals similar finding observed colorectal cancer mortality lower risk timepoints including procedure occurred 15 years earlier hr 064 95 ci 049083 female participants 065 050083 male participants colonoscopy intervention significantly lower colorectal cancer incidence undergo colonoscopy procedure occurred within 10 years females hr 070 95 ci 063077 15 years males 062 053072 compared receive colonoscopy individuals negative colonoscopy result remain lower risk colorectal cancer incidence mortality 15 years procedure current recommendation repeat screening 10 years individuals reassessed canadian institutes health research