Desirée Kozlowski, Marie Hutchinson, John Hurley, Joanne Rowley, Joanna Sutherland
The role of emotion in clinical decision making: an integrative literature review
BMC medical education
introduction irritable bowel syndrome ibs common functional gastrointestinal disorder characterized persistent abdominal pain variable bowel patterns impacting individuals quality life despite functional nature recent research indicated role inflammatory processes ibs development study aims investigate potential diagnostic value routine blood parameters relationship ibs methods retrospective analysis patients diagnosed ibs based rome iv criteria identified outpatient clinic hitit university erol olok teaching research hospital january 1 2023 may 1 2023 exclusion criteria encompassed specific medical conditions psychiatric disorders organic bowel pathologies cohort 100 ibs patients 100 healthy controls included comparison comprehensive blood data including neutrophil count lymphocyte count hemoglobin level red cell distribution width rdw mean corpuscular volume mcv mean platelet volume mpv platelet count collected statistical analyses conducted using spss windows version 260 ibm corp armonk ny descriptive statistics pearsons spearmans correlation coefficients mannwhitney u test chisquare test used analyze data results study cohort consisted 70 men 35 130 women 65 average age 5165 1464 years 52 years mean neutrophil count 46 15 429 control group 47 203 412 ibs group mean lymphocyte count 23 086 221 control group 23 082 223 ibs group indicating statistically significant difference p 0732 mean rdw measured 1362 107 134 control group 1368 118 1355 ibs group demonstrating significant difference p 0915 mean mcv mpv values showed substantial variation control ibs groups p 0649 p 0406 respectively conclusion study yield statistically robust outcomes underscores potential utilizing neutrophiltolymphocyte ratio nlr rdw mpv adjunctive diagnostic markers ibs routine costeffective parameters could enhance diagnostic process especially cases suspected ibs continued research essential unravel complete diagnostic potential clinical applicability