Sean P Ryan, Niall Cochrane, Michael P Bolognesi, Samuel S Wellman
Enhanced Total Hip Arthroplasty Education Using Augmented Reality: A Survey From a Tertiary Center
Orthopedics
normalisation medicinal recreational marijuana use increased importance fully understanding effects marijuana use individualand populationlevel health including prenatal exposure effects child development undertook systematic review literature examine longterm effects prenatal marijuana exposure neuropsychological function children aged 111 years primary research publications searched medline embase psychinfo cinahl ebscohost cochrane library global health eric 19802018 eligible articles documented neuropsychological outcomes children 111 years prenatally exposed marijuana studies exposure multiple prenatal drugs included results marijuana exposure reported separately substances data abstraction independently performed two reviewers using standardised protocol eligible articles n 21 data seven independent longitudinal studies high quality based newcastleottawa scale analyses found associations p 005 prenatal marijuana exposure decreased performance memory impulse control problemsolving quantitative reasoning verbal development visual analysis tests well increased performance attention global motion perception tests limitations included concurrent use substances among study participants potential underreporting publication biases nongeneralisable samples limited published results preventing direct comparison analyses specific effects prenatal marijuana exposure remain unclear warrant research larger number neuropsychological domains exhibit decreased versus increased psychological behavioural functions suggests exposure marijuana may harmful brain development function