Jantina de Vries|Susan Bull|Ogobara K. Doumbo|Muntaser E. Ibrahim|Odile Mercereau?Puijalon|Dominic Kwiatkowski|Michael Parker
Ethical issues in human genomics research in developing countries
University of Oxford|University of Oxford|University of Bamako|University of Khartoum|Institut Pasteur|Wellcome Centre for Human Genetics|University of Oxford|University of Oxford
genomewide association studies gwas provide powerful means identifying genetic variants play role common diseases studies present important ethical challenges increasing number gwas taking place lower income countries pressing need identify particular ethical challenges arising contexts paper draw upon experiences malariagen consortium identify specific ethical issues raised research africa asia oceania explore ethical issues three key areas protecting interests research participants regulation international collaborative genomics research protecting interests scientists low income countries regard participants important challenges raised community consultation consent genomics research raises ethical governance issues sample export ownership use archived samples complexity reviewing large international projects context protecting interests researchers low income countries discuss aspects data sharing capacity building need considered sustainable mutually beneficial collaborations many ethical issues raised genomics research conducted populations characterised lower average income literacy levels populations included malariagen important issues appropriately addressed research experience suggests ethical issues genomics research best identified analysed addressed ethics embedded design implementation research projects