Leah L. Zullig|Ryan Shaw|Matthew J. Crowley|Jennifer H. Lindquist|Steven C. Grambow|Eric D. Peterson|Bimal R. Shah|Hayden B. Bosworth
Association Between Perceived Life Chaos and Medication Adherence in a Postmyocardial Infarction Population
Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Durham VA Medical Center|Duke University|Clinical Research Institute|Duke University|Clinical Research Institute|Duke University|Clinical Research Institute
background benefits medication adherence control cardiovascular disease cvd well defined yet multiple studies identified poor adherence influence life chaos medication adherence unknown novel application instrument preliminary objective understand patient factors associated chaos main objective evaluate extent instrument designed measure life chaos associated cvdmedication nonadherence methods results using baseline data ongoing randomized trial improve postmyocardial infarction mi management multivariable logistic regression identified association life chaos cvdmedication nonadherence patients hypertension myocardial infarction past 3 years n406 nearly 43 reported cvdmedication nonadherence past month simple linear regression following associated higher life chaos medication nonadherence 186 95 confidence interval ci 096276 female sex 122 95 ci 022224 minority race 172 95 ci 078266 less high school education 205 95 ci 071339 low health literacy 206 95 ci 086326 inadequate financial status 193 95 ci 087300 married 209 95 ci 303 115 associated lower life chaos chaos quartile increased patients exhibited nonadherence logistic regression adjusting sex race marital status employment education health literacy financial status 1unit life chaos increase associated 7 increase odds ratio 107 95 ci 102112 odds reporting medication nonadherence conclusions results suggest life chaos may important determinant medication adherence life chaos screenings could identify risk nonadherence clinical trial registration url httpwwwclinicaltrialsgov unique identifier nct000901277