Tazeen H. Jafar|Muhammed Islam|Julian Hatcher|Saman K. Hashmi|Rasool Bux|Aamir Hameed Khan|Neil Poulter|S H Badruddin|Nish Chaturvedi
Community based lifestyle intervention for blood pressure reduction in children and young adults in developing country: cluster randomised controlled trial
Nutrition Sciences (Belgium)|Aga Khan University|Aga Khan University|Aga Khan University|Aga Khan University|Aga Khan University|Aga Khan University|Aga Khan University|Lung Institute|Imperial College London|Nutrition Sciences (Belgium)
bobjectiveb assess effectiveness community based lifestyle intervention blood pressure children young adults developing country setting bdesignb cluster randomised controlled trial bsettingb 12 randomly selected geographical census based clusters karachi pakistan bparticipantsb 4023 people aged 539 years binterventionb three monthly family based home health education delivered lay health workers bmain outcome measureb change blood pressure randomisation end followup 2 years bresultsb analysed using intention treat principle change systolic blood pressure adjusted age sex baseline blood pressure significant increased 15 95 confidence interval 11 19 mm hg control group 01 03 05 mm hg home health education group p difference groups002 findings diastolic blood pressure similar change 15 mm hg greater control group intervention group p0002 bconclusionsb simple family based home health education delivered trained lay health workers significantly ameliorated usual increase blood pressure age children young adults general population pakistan low income developing country strategy potentially feasible upscaling within existing healthcare systems indoasia btrial registrationb clinical trials nct00327574