Meiling Liu, Yan Lin, Ying Dai, Yongfang Deng, Xiao Chun, Yunxia Lv, Hongmei Yang, Fang He
A multi-dimensional EBP educational program to improve evidence-based practice and critical thinking of hospital-based nurses: Development, implementation, and preliminary outcomes
Nurse education in practice
observational studies highlighted significant association cholecystitis factors leading sudden death however specific relationship 2 fully elucidated primary objective study elucidate causal interplay cholecystitis augmented risk sudden cardiac death used largescale genetic summary data genomewide association study genetic summary statistics sourced 3 eminent repositories uk biobank n 463010 finngen consortium n 215027 european bioinformatics institute n 471251 employing 2sample mendelian randomization mr decipher causal interplay cholecystitis sudden death etiologies metaanalytical approach employed amalgamate findings derived disparate data sources primary mr methodologies used included inverse variance weighting random effects inverse variance weighting fixed effects maximum likelihood mregger weighted median subsequently performed heterogeneity testing polyvalency examination sensitivity analysis bolster robustness causal relationship assessments metaanalysis amalgamating variegated data sources revealed statistically significant inverse correlation cholecystitis ventricular arrhythmias odds ratio 0896 95 confidence interval 08260971 p 008 similarly inverse association observed cholecystitis aortic aneurysm odds ratio 0899 95 confidence interval 08510951 p 001 study substantiates absence direct causal link cholecystitis cerebrovascular accidents p 771 pulmonary embolism p 071 acute myocardial infarction p 388 direct causal correlation existed cholecystitis sudden death associated ventricular arrhythmias aortic aneurysms onset cholecystitis may mitigate risk sudden death due ventricular arrhythmias aortic aneurysms