Camilla Boslev Bårnes|Charlotte Suppli Ulrik
Asthma and Adherence to Inhaled Corticosteroids: Current Status and Future Perspectives
Hvidovre Hospital|University of Copenhagen|Hvidovre Hospital|University of Copenhagen
inhaled corticosteroids ics cornerstone maintenance asthma therapy however spite adherence ics remains low aim systematic literature review provide overview current knowledge adherence ics effects poor adherence means improve adherence total 19 studies met inclusion criteria 9 focusing level adherence 6 focusing effects poor adherence 7 focusing interventions improve adherence three studies focused one end points mean level adherence ics found 22 63 improvement exacerbation poor adherence associated youth africanamerican mild asthma 12 formal education poor communication healthcare provider whereas improved adherence associated prescribed fixedcombination therapy ics longacting 2 agonists good adherence associated higher fev1 lower percentage eosinophils sputum reduction hospitalizations less use oral corticosteroids lower mortality rate overall 24 exacerbations 60 asthmarelated hospitalizations could attributed poor adherence studies reported increase adherence following focused interventions followed improvement quality life symptoms fev1 oral corticosteroid use however 2 studies found difference healthcare utilization one observed effect symptoms one observed symptoms subjects intervention group compared control group good adherence ics asthma improves outcome remains low interventions improve adherence show varying results studies reporting increase adherence unfortunately necessarily improvement outcome even following successful interventions adherence remains low research needed explore barriers adherence interventions improvement