Yehia Mokhtar Farag, Carlos Horro, Marc Vaudel, Harald Barsnes
PeptideShaker Online: A User-Friendly Web-Based Framework for the Identification of Mass Spectrometry-Based Proteomics Data
Journal of proteome research
three seven percent preschoolers developmental problems child psychiatric disorders randomized controlled trials rcts indicate interventions early childhood education care ecec improve longterm outcomes children disadvantaged backgrounds unknown effects generalize beyond wellstructured context rcts children may disadvantaged background developmental problems psychiatric disorders used data populationbased norwegian mother father child cohort study recruiting pregnant women 1999 2009 child followup ages 6 18 36 months ages 5 7 8 years substudy included 2499 children developmental problems psychiatric disorders age five investigated effects special educational assistance age five motherreported internalizing externalizing communication problems age eight analysed bias due treatment indication directed acyclic graphs adjusted treatment predictors reduce bias estimated effects different patient groups outcome domains hierarchical bayesian model adjusted analysis preschoolers received special educational assistance average 01 004016 standardised mean deviation fewer psychosocial difficulties elementary school sample children mostly higher socioeconomic backgrounds estimate positive effects special educational assistance transition preschool school years may therefore considered intervention preschoolers developmental behaviour problems research improved measurements treatment outcomes needed solidify findings identify success factors implementation special educational assistance ecec