Wenxun Lin, Xi Xie, Zhijun Luo, Xiaoqi Chen, Heng Cao, Xun Fang, You Song, Xujing Yuan, Xiaojing Liu, Rong Du
Early identification of macrophage activation syndrome secondary to systemic lupus erythematosus with machine learning
Arthritis research & therapy
study addressed covid19 outbreak nursing home residents vaccinated two doses comirnaty thirty previously infection outbreaks closed communities opportunities study entire clinical spectrum disease case effect hybrid immunity transmission infection progression viral load descriptive retrospective cohort study resident population carried attack rates calculated one four stages disease infection symptomatic infection hospitalization death relative risks rr estimated using simple multivariate poisson regression stages attack rate 59 5695 clinical spectrum sexes notable protective effect hybrid immunity transmission 67 terms progression hybrid immunity lower risk symptomatic infection nasopharyngeal viral load significantly lower individuals hybrid immunity asymptomatic individuals supporting idea lower transmissibility group age identified risk factor disease progression molecular analysis identified delta b16172 variant patients air sample supporting aerosol transmission closed poorly ventilated environments study provides comprehensive view outbreak vaccinated nursing home highlighting importance hybrid immunity results support individual consideration previous infection history assessing risk covid19 contributing understanding evolution pandemic future