Hai-Lian Chen, Chun-Hu Li, Pei-Yao Zhai, Xun Zhuang, Yu-Long Lian, Xue Qiao, Jian Feng, Zu-Shu Qian, Gang Qin
Survival and disease burden analyses of occupational pneumoconiosis during 1958-2021 in Huangshi city, China: a retrospective cohort study
BMC public health
coronary pressure indices assess coronary artery disease currently underused patients aortic stenosis due many potential physiological effects might hinder interpretation studies varying sample sizes provided us conflicting results effect transcatheter aortic valve replacement tavr indices aim metaanalysis study immediate longterm effects tavr fractional flow reserve ffr nonhyperemic pressure ratios nhprs lesionspecific coronary pressure data extracted 6 studies resulting 147 lesions immediate change ffr analysis 105 nhpr analysis investigate longterm changes 93 lesions ffr analysis 68 nhpr analysis found lesion data pooled compared paired tests immediately tavr ffr decreased significantly 0013000406 sd p 00002 nhpr remained stable 0000300675 p 09675 longterm tavr ffr decreased significantly 0023000747 p 00038 nhpr increased nonsignificantly 0016600699 p 00543 borderline nhpr lesions considered increase became significant 0024900441 p 00015 sensitivity analysis confirmed results borderline lesions tavr resulted small significant opposite changes ffr nhpr using standard cutoffs patients severe aortic stenosis ffr might underestimate physiological significance coronary lesion nhprs might overestimate significance described changes play clinically relevant role borderline lesions therefore even patients aortic stenosis overtly positive negative physiological assessment trusted