Kathryn E. Flynn|Li Lin|Jill M. Cyranowski|Bryce B. Reeve|Jennifer Barsky Reese|Diana D. Jeffery|Ashley Wilder Smith|Laura S. Porter|Carrie B. Dombeck|Deborah Watkins Bruner|Francis J. Keefe|Kevin P. Weinfurt
Development of the NIH PROMIS® Sexual Function and Satisfaction Measures in Patients with Cancer
Clinical Research Institute|Duke University|Duke University Hospital|Duke Medical Center|Clinical Research Institute|Duke University|University of Pittsburgh Medical Center|University of North Carolina at Chapel Hill|Johns Hopkins Medicine|Johns Hopkins University|Health Affairs|National Cancer Institute|Duke University Hospital|Duke Medical Center|Clinical Research Institute|Duke University|Emory University|Duke University Hospital|Duke Medical Center|Clinical Research Institute|Duke University|Duke University Hospital|Duke Medical Center
describe development validation patientreported outcomes measurement information system sexual function satisfaction promis sexfs national institutes health measures version 10 cancer populationsto develop customizable selfreport measure sexual function satisfaction part us national institutes health promis networkour multidisciplinary working group followed comprehensive protocol developing psychometrically robust patientreported outcome measures including qualitative scale development quantitative psychometric evaluation development performed extensive literature review conducted 16 focus groups cancer patients multiple discussions clinicians evaluated candidate items cognitive testing patients administered items 819 cancer patients items calibrated using itemresponse theory evaluated reliability validitythe promis sexfs measures version 10 include 81 items 11 domains interest sexual activity lubrication vaginal discomfort erectile function global satisfaction sex life orgasm anal discomfort therapeutic aids sexual activities interfering factors screener questionsin addition content validity patients indicate items cover important aspects experiences face validity patients indicate items measure sexual function satisfaction measure shows evidence discriminant validity domains discriminate groups expected different convergent validity strong correlations scores promis scores conceptually similar older measures sexual function well favorable testretest reliability among people expected change interclass correlations two administrations instrument 1 month apartthe promis sexfs offers researchers reliable valid set tools measure selfreported sexual function satisfaction among diverse men women measures customizable researchers select relevant domains items comprising domains study