Yao Yu, Guiyi Yang, Yixuan Qin, Linhan Fang, Yuxuan Liao, Wenxuan Bai, Jianzhen Wu, Pengfei Rong
The correlation between parents' education attainment and humanistic literacy of eight-year medical students
International journal of medical education
stroke second leading cause death worldwide major cause longterm neurological disability imposing enormous financial burden families society study aimed identify predictors stroke patients construct nomogram prediction model based predictors retrospective study included 11435 participants aged 20 years selected nhanes 20112018 randomly selected subjects n 8531 75 remaining subjects comprised development validation groups respectively least absolute shrinkage selection operator lasso binomial logistic regression models used select optimal predictive variables stroke probability calculated using predictorbased nomogram nomogram performance assessed area receiver operating characteristic curve auc calibration curve 1000 bootstrap resample validations decision curve analysis dca performed evaluate clinical utility nomogram according minimum criteria nonzero coefficients lasso logistic regression screening older age lower education level lower family income hypertension depression status diabetes heavy smoking heavy drinking trouble sleeping congestive heart failure chf coronary heart disease chd angina pectoris myocardial infarction independently associated higher stroke risk nomogram model stroke patient risk established based predictors auc c statistic nomogram 0843 95 ci 0818608430 development group 0826 95 ci 07811 08716 validation group calibration curves 1000 bootstraps displayed good fit actual predicted probabilities development validation groups dca showed model development validation groups net benefit risk thresholds 002 0025 respectively study effectively established nomogram including demographic characteristics vascular risk factors emotional factors lifestyle behaviors predict stroke risk nomogram helpful screening highrisk stroke individuals could assist physicians making better treatment decisions reduce stroke occurrence