Ann M Sam, Samuel L Odom, Brianne Tomaszewski, Yolanda Perkins, Ann W Cox
Employing Evidence-Based Practices for Children with Autism in Elementary Schools
Journal of autism and developmental disorders
understanding transcriptome become essential step towards full interpretation biological function cell tissue even organ many tools available either processing analysing transcriptome data visualizing analysis results however existing tools limited data single sequencing platform several could handle one analysis module far enough meet requirements users especially without advanced programming skills hence still lack opensource toolkit enables bioinformatician nonbioinformatician users process analyze large transcriptome data different sequencing platforms visualize results present linuxbased toolkit rnacombine automatically perform quality assessment downstream analysis transcriptome data generated different sequencing platforms including bulk rnaseq illumina platform single cell rnaseq 10x genomics isoseq pacbio visualization results besides toolkit implemented least 10 analysis modules toolkits examined study source codes rnacombine available github httpsgithubcomdongxuemin666rnacombine results suggest rnacombine reliable tool transcriptome data processing result interpretation bioinformaticians nonbioinformaticians