Charles D. H. Parry|Neo K. Morojele|Bronwyn Myers|Connie T. Kekwaletswe|Samuel Manda|Katherine Sorsdahl|Gita Ramjee|Judith A. Hahn|Jürgen Rehm|Paul A. Shuper
Efficacy of an alcohol-focused intervention for improving adherence to antiretroviral therapy (ART) and HIV treatment outcomes – a randomised controlled trial protocol
South African Medical Research Council|South African Medical Research Council|South African Medical Research Council|South African Medical Research Council|South African Medical Research Council|University of Cape Town|South African Medical Research Council|University of California, San Francisco|Centre for Addiction and Mental Health|Centre for Addiction and Mental Health
little research examined whether alcohol reduction interventions improve antiretroviral therapy art adherence hiv treatment outcomes study assesses efficacy intervention reducing alcohol use among hiv patients art hazardousharmful drinkers specific aims include adapting blended motivational interviewing mi problem solving therapy pst intervention use hiv patients evaluating efficacy intervention reducing alcohol consumption assessing counsellors participants perceptions intervention randomised controlled trial evaluate intervention among art patients public hospitalbased hiv clinics tshwane south africa recruit patients hivpositive art least 3 months classified harmfulhazardous drinkers using audit3 eligible patients randomly assigned one three conditions patients experimental group receive mipst intervention reduce harmfulhazardous alcohol use patients equalattention wellness intervention group receive intervention focused addressing health risk behaviours patients control condition receive treatment usual participants complete intervieweradministered questionnaire baseline 3 6 12 months postrandomisation assess alcohol consumption art adherence physical mental health also collect biological specimens test recent alcohol consumption cd4 counts hiv rna viral loads primary outcome reduction volume alcohol consumed secondary outcomes include reduction harmfulhazardous use alcohol reduction biological markers drinking increase adherence rates reductions viral loads increases cd4 tcell counts process evaluation ascertain counsellors participants perceptions acceptability effectiveness interventions obtained ethical approval approval study sites regional provincial health departments study implications clinicians researchers policy makers provide efficacy data reduce harmfulhazardous alcohol consumption among hiv patients shed light whether reducing alcohol consumption impacts hiv treatment adherence outcomes pan african clinical trials register number pactr201405000815100