Amanda H. Salanitro|Sunil Kripalani|JoAnne N. Resnic|Stephanie Mueller|Tosha B. Wetterneck|Katherine Taylor Haynes|Jason Stein|Peter J. Kaboli|Stephanie Labonville|Edward Etchells|Daniel J. Cobaugh|David Hanson|Jeffrey L. Greenwald|Mark Williams|Jeffrey L. Schnipper
Rationale and design of the Multicenter Medication Reconciliation Quality Improvement Study (MARQUIS)
VA Tennessee Valley Healthcare System|Geriatric Research Education and Clinical Center|Vanderbilt University|Brigham and Women's Hospital|Harvard University|University of Wisconsin–Madison|Vanderbilt University|Emory University|Iowa City VA Health Care System|University of Iowa|Brigham and Women's Hospital|Sunnybrook Health Science Centre|Health Sciences Centre|University of Toronto|American Society of Health-System Pharmacists|American Association of Critical-Care Nurses|Massachusetts General Hospital|Harvard University|Northwestern University|Harvard University|Brigham and Women's Hospital
unresolved medication discrepancies hospitalization contribute adverse drug events resulting patient harm discrepancies reduced performing medication reconciliation however effective implementation medication reconciliation proven challenging goals multicenter medication reconciliation quality improvement study marquis operationalize best practices inpatient medication reconciliation test effect potentially harmful unintentional medication discrepancies understand barriers facilitators successful implementationsix us hospitals participating quality improvement mentored implementation study hospital collected baseline data primary outcome number potentially harmful unintentional medication discrepancies per patient determined trained onsite pharmacist taking gold standard medication history guidance mentors site also begun implement one 11 best practices improve medication reconciliation understand effect implemented interventions hospital staff culture performing mixed methods program evaluation including surveys interviews focus groups front line staff hospital leadersat baseline number unintentional medication discrepancies admission discharge orders per patient varies site 235 467 mean335 discrepancies due history errors mean 212 per patient opposed reconciliation errors mean 123 per patient potentially harmful medication discrepancies averages 045 per patient varies site 013 082 per patient discuss several barriers implementation encountered thus far end anticipate marquis tools lessons learned potential decrease medication discrepancies improve patient outcomesclinicaltrialsgov identifier nct01337063