Franziska Baessler, Joshua Weidlich, Sophie Schweizer, Anja Ciprianidis, Marina Bartolovic, Ali Zafar, Michael Wolf, Fabienne Louise Wagner, Tabea Chiara Baumann, André L Mihaljevic, Beate Ditzen, Daniela Roesch-Ely, Christoph Nikendei, Jobst-Hendrik Schultz
What and how are students taught about communicating risks to patients? Analysis of a medical curriculum
PloS one
realworld evidence rwe increasingly used medical regulatory decisions yet concerns persist regarding reproducibility hence validity study addresses reproducibility challenges associated diversity across realworld data sources rwds repurposed secondary use pharmacoepidemiologic studies aims identify describe characterize practices recommendations tools collecting reporting diversity across rwdss explore leveraging diversity could improve quality evidence preliminary phase keywords literature search selection tool designed using set documents considered key coauthors next systematic search conducted december 2021 resulting documents screened based titles abstracts based full texts using selection tool selected documents reviewed extract information topics related collecting reporting rwds diversity content analysis topics identified explicit latent themes across 91 selected documents 12 topics identified 9 dimensions used describe rwds organization accessing data source data originator prompt inclusion population content data dictionary time span healthcare system culture data quality tools summarize dimensions challenges opportunities arising diversity thirtysix themes identified within dimensions opportunities arising data diversity included multiple imputation standardization dimensions identified across large number publications lay foundation formal guidance reporting diversity data sources facilitate interpretation enhance replicability validity rwe