Lijing Zou, Anyan Huang, Kusheng Wu, Xuanzhi Zhang, Kaiguo Zhang, Wanyi Wen, Liwen Guan, Yanhong Huang
Home reading environment, sociometric and demographic factors associated with dyslexia in primary school students in China: A case-control study
Heliyon
syndrome common genetic cause intellectual disability affecting 700800 babies annually uk wu j morris j eur j hum genet 2110169 2013 children syndrome difficulties developing language skills difficulties longterm negative consequences aspects lives including social development education employment opportunities emotional wellbeing mental health irwin lg et al 2007 aspects potential improved targeted early language intervention parents children together pact parentdelivered early language teaching programme typically developing preschool children risk language delays previous project burgoyne k j child psychol psychiatry 59554555 2018 showed pact leads improvements childrens language early literacy skills team worked closely six families adapt pact children syndrome aim current study conduct feasibility randomised controlled trial rct evaluate feasibility definitive rct explore initial evidence adapted programmes potential support childrens language literacy development twoarm feasibility randomised controlled trial children randomly allocated either pactds group waiting control group receive intervention end project aim recruit 2830 children syndrome aged 36 years parentscaregivers take part pactds group trained deliver pactds every day 20 min day 5 days week child 30 weeks collect data using assessments child language early literacy measures parent wellbeing qualitative surveys interviews monitoring data explore trial feasibility including recruitment retention families adherence acceptability intervention cost benefits data collected intervention immediately 30week intervention programme 6 months intervention ends clear progression criteria used assess suitability definitive trial study represents initial steps developing definitive trial pactds programme add limited evidence base early language intervention children syndrome programme research potential make significant advancements early language intervention research practice group trial registered isrctn registry study id isrctn63251282 registered 14 july 2023