Laura C. Pinheiro|Molly McFatrich|Nicole Lucas|Jennifer Walker|Janice S. Withycombe|Pamela S. Hinds|Lillian Sung|Deborah Tomlinson|David R. Freyer|Jennifer W. Mack|Justin N. Baker|Bryce B. Reeve
Child and adolescent self-report symptom measurement in pediatric oncology research: a systematic literature review
Cornell College|Duke University|University of North Carolina at Chapel Hill|University of North Carolina at Chapel Hill|Emory University|Children's National|George Washington University|Institute for Clinical Evaluative Sciences|Hospital for Sick Children|SickKids Foundation|Institute for Clinical Evaluative Sciences|Hospital for Sick Children|SickKids Foundation|Children's Hospital of Los Angeles|Children's Center|Dana-Farber Cancer Institute|St. Jude Children's Research Hospital|Duke University
previous work pediatric oncology found clinicians parents tend underreport frequency severity treatmentrelated symptoms compared child selfreport need identify highquality selfreport instruments used pediatric oncology research studies studys objective conduct systematic literature review existing english language instruments used measure selfreported symptoms children adolescents undergoing cancer treatment comprehensive literature search conducted medlinepubmed embase cinahl psycinfo identify relevant articles published november 10 2016 using prespecified inclusionexclusion criteria six trained reviewers carefully screened abstracts fulltext articles eligibility 7738 nonduplicate articles identified literature search forty articles met eligibility criteria within articles 38 selfreport english symptom instruments studies evaluated crosssectional psychometric properties reliability validity ten studies assessed instruments responsiveness ability detect changes symptoms time eight instruments met criteria use future longitudinal pediatric oncology studies systematic review aids pediatric oncology researchers identifying selecting appropriate symptom measures strong psychometric evidence studies enhancing childs voice pediatric oncology research studies allows us better understand impact cancer treatment lives children