Guilhem Pagès, Max Puckeridge, Guo Liangfeng, Yee Ling Tan, Chacko Jacob, Marc Garland, Philip W Kuchel
Transmembrane exchange of hyperpolarized 13C-urea in human erythrocytes: subminute timescale kinetic analysis
Biophysical journal
unknown optimal extent sinus surgery pediatric patients orbital cellulitis aim determine nationwide incidence sinus procedures used treat pediatric orbital cellulitis additionally sought identify patientfactors influence multiprocedural approach crosssectional analysis 15260 cases primary pediatric orbital cellulitis identified kids inpatient database kid january 1 2003 december 31 2012 cases included contained primary diagnosis code orbital cellulitis frequency sinus procedures relation pediatric age cohort noted 8 years versus 920 years comorbidities cost lengthofstay compared age cohorts multivariate models investigated patientfactors associated multiple sinus procedures patientfactors affected hospital costs lengthofstay children 8 years age constituted 67 cases n 10290 1103 cases 72 treated least one defined sinus procedure 712 cases documented one sinus procedure younger cohort 8 years exhibited fewer sinus procedures lower rate reoperation 46 vs 128 p 001 51 vs 77 p 001 respectively presence cellulitisabscess face strongest predictor multiple sinus procedures 1982 p 033 patients acute sinusitis 8 years similarly increased odds multiprocedural approach 1333 p 049 1367 p 032 respectively multivariate analysis cost lengthofstay found patients 8 years incurred 14 longer hospital stays increase costs 9 compared younger patients p 001 p 039 respectively secondary diagnosis largest effect lengthofstay cost intracranical abscess 2352 p 001 2752 p 001 respectively nationwide population pediatric patients primary orbital cellulitis incidence sinus surgery 72 cases patients 8 years 28fold increase compared younger patients additionally nearly twothirds patients treated sinus surgery multiple sinus procedures high incidence multiple sinus procedures suggests prospective studies needed elucidate extent drainage associated best patient outcomes