Lindsay A Tanskey, Jeanne P Goldberg, Kenneth Chui, Aviva Must, Jennifer M Sacheck
Accelerated Summer Weight Gain in a Low-Income, Ethnically Diverse Sample of Elementary School Children in Massachusetts
Childhood obesity (Print)
explore changes cerebral microstructure patients noiseinduced hearing loss nihl using diffusion tensor imaging dti overall 122 patients nihl mild mp n 79 relatively severe patients including moderate severe rsp n 32 undetermined lost followup n 11 84 healthy controls hcs enrolled clinical data including age education level hearing threshold occupation type noise exposure time scale scores including minimental state examination mmse tinnitus handicap inventory thi hamilton anxiety scale hama collected analyzed participants underwent t1wi3dfspgr dti tractbased spatial statistics region interest roi analysis used assessment final sample included 71 mp 28 rsp 75 hcs hama scores three groups significantly different p 05 noise exposure times hearing thresholds hama scores mp rsp significantly different p 05 noise exposure time positively correlated hearing threshold negatively correlated hama scores p 05 whereas thi scores positively correlated hearing threshold p 05 dti analysis showed dti parameters fractional anisotropy fa axial diffusivity ad mean diffusivity md radial diffusivity rd significantly different left inferior longitudinal fasciculus ilf left inferior frontooccipital fasciculus ifof three groups p 05 addition fa values significantly lower bilateral corticospinal tract cst right frontopontine tract fpt right forceps major left superior longitudinal fasciculus temporal part slf left cingulum hippocampus ch mp rsp hcs p 05 ad values showed diverse changes bilateral cst left ifof right anterior thalamic radiation right external capsule ec right slf right superior cerebellar peduncle scp mp rsp relative hc p 05 however significant differences among bilateral auditory cortex rois three groups p 05 significant negative correlation fa hama scores left ifofilf right fpt left slf left ch three groups p 05 significant positive correlation ad hama scores left ifofilf right ec three groups p 05 significantly positive correlations rdmd hama scores left ifofilf three groups p 05 significant negative correlation ad right scp noise exposure time mp rsp groups p 05 ad md rd left roi significantly positively correlated hearing threshold mp rsp groups p 05 whereas fa right roi significantly positively correlated hama scores three groups p 05 changes white matter wm microstructure may related hearing loss caused noise exposure wm structural abnormalities patients nihl mainly located syndesmotic fibers temporooccipital region affected auditory language pathways confirmed auditory pathways abnormal structural connectivity patients nihl