Jyoti Shrestha|Himal Shrestha|Miyasha Prajapati|Astha Karkee|Anjana Maharjan
Adverse Effects of Oral Hypoglycemic Agents and Adherence to them among Patients with Type 2 Diabetes Mellitus in Nepal
Kathmandu University|Kathmandu University|Kathmandu University|Kathmandu University|Kathmandu University
introduction oral hypoglycemic agents ohas common drugs used type 2 diabetes mellitus various established adverse effects related use including hypoglycemia weight gain gastrointestinal disturbance lactic acidosis fluid retention however pattern adverse effects related ohas nepalese patients still needs explored study aims determine pattern adverse effects resulting use ohas among type 2 diabetes mellitus patients adherence medicationx0d methods diabetic patients met inclusion criteria enrolled study informed consent patients interviewed evaluated per designed proforma mainly studied common drug used adverse effects drugs occurrence hypoglycemia adherence treatmentx0d results study comprised 183 patients mean age 5873 years sd 1295 fiftysix 306 patients said developed adverse effects drugs 21 115 reported treating physician common adverse effect related central nervous system tingling sensation hands feet dizziness drowsiness etc though 91 497 patients developed symptoms suggestive hypoglycemia 31 169 knew due hypoglycemia majority patients n 143 781 administered drugs prescribed physician among defaulters important reasons failure properly administer drugs forgetfulness 825 n 33 n 40 cases among study variables family history chronic illness p 0046 information adverse effects physician p 0001 significant relationship incidence adverse effects whereas none significant relationship adherence hypoglycemic medicationx0d conclusion incidence adverse effects high hypoglycemia occurring 497 cases though onethird recognized due hypoglycemia patients type 2 diabetes mellitus family history chronic illness information adverse effects physician significant relationship incidence adverse effects hypoglycemic treatment