Michele L. Dreyfuss|Gernard Msamanga|Donna Spiegelman|David J. Hunter|Ernest J.N. Urassa|Ellen Hertzmark|Wafaie Fawzi
Determinants of low birth weight among HIV-infected pregnant women in Tanzania
Muhimbili University of Health and Allied Sciences|Muhimbili University of Health and Allied Sciences|Muhimbili University of Health and Allied Sciences|Muhimbili University of Health and Allied Sciences|Muhimbili University of Health and Allied Sciences|Muhimbili University of Health and Allied Sciences|Muhimbili University of Health and Allied Sciences
low birth weight lbw increases risk infant death little known causes among hivinfected populations subsaharan africawe assessed sociodemographic nutritional immunologic parasitic infant risk factors birth weight lbw smallforgestationalage sga status cohort 822 hivpositive women enrolled clinical trial vitamin supplementation pregnancy outcomes dar es salaam tanzaniawomen enrolled prenatal care clinics second trimester time blood stool urine genital specimens collected anthropometric measurements sociodemographic data recorded birth weight measured hospital deliverythe mean sd birth weight 3015 508 g 111 newborns weighed 2500 g lbw 115 sga multivariate analyses maternal weight enrollment low cd8 cell count inversely associated lbw advancedstage hiv disease previous history preterm birth plasmodium falciparum malaria helmintic infection associated higher risk lbw intestinal parasites entamoeba histolytica strongyloides stercoralis predictors lbw despite low prevalence cohort multivariateadjusted linear regression model bmi midupper arm circumference cd4 cell count 200 x 106 cellsl 200 cellsmm3 primiparity maternal literacy infant hiv infection birth significantly associated birth weight addition risk factors included lbw model determinants sga included maternal weight low serum vitamin e concentration candidiasis malaria infant hiv infection birthprevention hiv disease progression vertical transmission improved nutritional status better management malaria intestinal parasitic infections likely reduce incidence lbw tanzania