Moses K. Nyongesa|Patrick N. Mwangala|Paul Mwangi|Martha Kombe|Charles R. Newton|Amina Abubakar
Neurocognitive and mental health outcomes and association with quality of life among adults living with HIV: a cross-sectional focus on a low-literacy population from coastal Kenya
Kenya Medical Research Institute|Kenya Medical Research Institute|Kenya Medical Research Institute|Kenya Medical Research Institute|Pwani University|Kenya Medical Research Institute|University of Oxford|Pwani University|Kenya Medical Research Institute|University of Oxford
objectives aim compare neurocognitive performance mental health outcome adults living hiv antiretroviral therapy community controls low literacy furthermore also wanted explore relationship outcomes quality life among adults living hiv study design descriptive crosssectional study setting study conducted kilifi county region located kenyan coast participants participants consisted consecutive sample 84 adults living hiv 83 randomly selected community controls 8 years schooling participants assessed nonverbal intelligence verbal working memory executive functioning major depression inventory quality life measure rand sf36 also administered results using analysis covariance found statistically significant group differences adults living hiv community controls neurocognitive tests except marginal difference nonverbal intelligence test f 1 158383 p005 however depressive scores adults living hiv significantly higher controls f 1 1581156 plt001 also quality life scores adults living hiv significantly lower controls f 1 158462 p003 hivinfected group results multivariable linear regression analysis showed increasing depressive scores significantly associated poorer quality life 117 95 ci 155 080 plt001 conclusion findings suggest adults lowliteracy levels living hiv antiretroviral medication kenyan coast significant cognitive deficits compared uninfected counterparts however mental health compared hivuninfected adults remains poorer quality life may deteriorate hiv depressive symptoms cooccur