C. Acquadro|K Conway|Asha Hareendran|Neil K. Aaronson
Literature Review of Methods to Translate Health-Related Quality of Life Questionnaires for Use in Multinational Clinical Trials
Mapi Research Trust
conducted literature review respond regulatory concerns quality translated patientreported outcome questionnaires main objective answer two questions methods common differ evidence superiority one method anotherwe identified 891 references searching medline embase mapi research trusts database qualityoflifequestionnaireshealth status indicators matched translatingtranslation issuescrosscultural research crosscultural comparison articles included proposed compared criticized translation methodsfortyfive articles met inclusion criteria 23 representing 17 sets methods 22 reviews articles recommend multistep approach involving centralized review process nevertheless group proposes sequence translation events weights step differently evidence demonstrating rigorous multistep procedure leads better translations nevertheless empirical evidence favor one specific methodwe need empirical research translation methodologies several points emerge review first producing highquality translations laborintensive second availability standardized guidelines centralized review procedures improves efficiency production translations although find evidence favor one method strongly advise researchers adopt multistep approach line recent food drug administration recommendations developed checklist summarizing steps used translations used evaluate rigor applied methodologies