Ann Clark|Anne O’Hare|Joanna Watson|Wendy Cohen|Hilary Cowie|R. A. Elton|Jamal Nasir|Jonathan R. Seckl
Severe receptive language disorder in childhood--familial aspects and long-term outcomes: results from a Scottish study
University of Edinburgh|Queen Margaret University|University of Edinburgh|University of Edinburgh|University of Edinburgh|University of Sheffield|The Queen's Medical Research Institute
background aims little known familial characteristics children severe receptive specific language impairment sli affected children likely longterm problems expressive sli date described small cohorts within sli populations therefore aimed describe clinical familial characteristics severe receptive sli defined rigorous phenotype establish whether nonword repetition showed relationship language impairment families methods crosssectional study children met icd10 f802 criteria receptive sli school entry siblings genetic parents standardised measures language nonverbal iq phonological auditory memory speech sound inventory results mean 6 years school entry severe receptive sli 58 participants normal mean standard deviation nonverbal iq 3 two attained language measures normal range one third still severe receptive language impairment one third siblings known affected language levels outside normal range phonological auditory memory impaired family members conclusion severe receptive sli nearly always associated equally severe reduction expressive language skills language impairment siblings may go undetected yet high risk family members weak phonological auditory memory skills suggesting could marker language acquisition difficulties receptive sli rarely resolves trials therapy urgently needed