Francis L. Weng|Sheenu Chandwani|Karen Kurtyka|Christopher Zacker|Marie A. Chisholm?Burns|Kitaw Demissie
Prevalence and correlates of medication non-adherence among kidney transplant recipients more than 6 months post-transplant: a cross-sectional study
Saint Barnabas Medical Center|Rutgers, The State University of New Jersey|Rutgers, The State University of New Jersey|Tris Pharma (United States)|University of Tennessee Health Science Center|Rutgers, The State University of New Jersey
among kidney transplant recipients nonadherence immunosuppressive medications frequently precedes allograft loss sought determine prevalence correlates medication nonadherence among kidney transplant recipientswe performed singlecenter crosssectional study kidney transplant recipients least 6 months posttransplant measured selfreported adherence using immunosuppressive therapy adherence scale itas scored 0 12 higher scores indicate increased adherence barriers adherence using immunosuppressive therapy barriers scale itbs also used validated scales measure perceived stress health literacy anxiety depression interpersonal supportthe 252 patients included study 599 male 270 black median 29 years posttransplant interquartile range iqr 1458 itas 591 scored perfect 12 266 scored 1011 143 scored 09 univariate models nonadherence defined itas score 9 significantly associated increased scores scales perceived stress 112 95 ci 101125 depression 114 95 ci 102128 selfreported barriers adherence itbs 115 95 ci 108122 adjusting sociodemographic factors stress depression associated nonadherence higher scores itbs corresponding selfdescribed barriers adherence associated lower scores itas p 0001 several individual barriers associated nonadherenceamong prevalent kidney transplant recipients minority nonadherent practical barriers adherence may serve promising targets future interventions