Sonia Coelho Mosch|Jeffrey E. Max|Daniel Tranel
A Matched Lesion Analysis of Childhood Versus Adult-Onset Brain Injury Due to Unilateral Stroke
University of Iowa
literature neuroplasticity lacks direct comparison chronic neuropsychological social outcomes following brain damage acquired childhood versus adulthood lesions matched across adults children size locationwe paired adults children similar unilateral stroke lesions compared chronic neuropsychological social outcomes quantitative comparisons conducted well qualitative analyses subject pair focusing specific domains cognitive impairment changes social functioningwe found learning memory impairments common children adults left hemispherelesioned children normal speechlanguage ratings whereas adult counterparts borderline impaired impairments social functioning highly associated hemispheric side damage adults children specifically adults right hemisphere lesions developed social defects much frequently adults left hemisphere lesions whereas asymmetry evident children importantly though overarching finding high degree similarity chronic neuropsychological social function outcomes adults children similarly located brain lesions due unilateral strokeon balance findings suggest lesion location size prepotent factors determining neuropsychological social recovery stroke