Rachel Romeo|Joanna A. Christodoulou|Kelly Halverson|Jack Murtagh|Abigail Cyr|Carly Schimmel|Patricia P. Chang|Pamela E. Hook|John D. E. Gabrieli
Socioeconomic Status and Reading Disability: Neuroanatomy and Plasticity in Response to Intervention
Harvard University|McGovern Institute for Brain Research|Massachusetts Institute of Technology|McGovern Institute for Brain Research|Massachusetts Institute of Technology|MGH Institute of Health Professions|McGovern Institute for Brain Research|Massachusetts Institute of Technology|McGovern Institute for Brain Research|Massachusetts Institute of Technology|McGovern Institute for Brain Research|Massachusetts Institute of Technology|McGovern Institute for Brain Research|Massachusetts Institute of Technology|McGovern Institute for Brain Research|Massachusetts Institute of Technology|MGH Institute of Health Professions|McGovern Institute for Brain Research|Massachusetts Institute of Technology|IIT@MIT
although reading disability rd socioeconomic status ses independently associated variation reading ability brain structurefunction joint influence ses rd neuroanatomy andor response intervention unknown total 65 children rd ages 69 diverse ses assigned intensive 6week summer reading intervention n 40 waitinglist control group n 25 children completed standardized reading assessments magnetic resonance imaging measure cortical thickness baseline higher ses correlated greater vocabulary greater cortical thickness bilateral perisylvian supramarginal regionsespecially left pars opercularis within intervention group lower ses associated greater reading improvement greater cortical thickening across broad bilateral occipitotemporal temporoparietal regions following intervention additionally treatment responders n 20 compared treatment nonresponders n 19 exhibited significantly greater cortical thickening within similar regions waiting control nonresponder groups exhibited developmentally typical nonsignificant cortical thinning time period findings indicate effective summer reading intervention coupled cortical growth especially beneficial children rd come lowerses home environments