Paris Cooke, Mercedes M Morales-Alemán, Gwendolyn Ferreti
Healthcare Provider Perceptions of the Use of Medical Interpretation in Primary Care
Southern medical journal
approximately 30 people epilepsy seizures wellcontrolled antiseizure medication asm condition called treatment resistant epilepsy tre associated increased morbidity mortality substantially impacts quality life individual family nonresponsiveness asms leads many people tre seek alternative therapies cannabinoidbased medication particularly cannabidiol cbd without medical professional advice due part widespread reporting media benefits cbd seizures forms epilepsy adults tre opting add cbd existing treatment regime completed prospective observational longitudinal quasiexperimental timeseries study hypothesized adjunctive cbd use would positively impact participants quality life psychological wellbeing comparison baseline period without cbd use participants followed period approximately six months approximately one month baseline prior initiation cbd use approximately five months initiation cbd use participants provided urine samples completed behavioral questionnaires assessed quality life anxietydepression adverse events baseline two times cbd use complete case analyses n 10 showed statistically significant improvement quality life statistically significant decrease anxiety symptoms statistically significant decrease experience adverse events time p 005 improvements noted experience depression symptoms reach statistical significance urinalysis revealed majority participants cbdmetabolites system beginning study confirmed presence cbdmetabolites participants urine cbd added treatment regime analysis missing data using multiple imputation supported findings complete case analysis small group individuals tre varying etiologies adjunctive use artisanal cbd associated improvements behavioral psychological symptoms tre well improved medication tolerability