Emily J Knight, Aaron I Krakowski, Edward G Freedman, John S Butler, Sophie Molholm, John J Foxe
Attentional influences on neural processing of biological motion in typically developing children and those on the autism spectrum
Molecular autism
study performed derive validate prognostic prediction model individualized estimation mortality risk among frail oldest old aged 80 years older analysis based prospective open cohort study chinese longevity health longitudinal survey total 14 118 frail oldest old included 2002 wave 2014 waves study outcome allcause mortality available predictors included frailty demographics social factors cox models used estimate coefficients predictors least absolute shrinkage selection operator used selecting predictors model performance measured discrimination calibration internal validation bootstrapping also developed nomogram visualize predict 3year mortality risk based obtained prognostic prediction model 16years followup 10 410 7642 deaths identified final model comprises following factors frailty age sex race birthplace education occupation marital status residence economic condition number children question ask help first trouble model valid predictive ability measured validated harrells c statistic 0602 calibration plots study provides basic prognostic prediction model quantify absolute mortality risk frail oldest old future studies needed firstly update adjust perform external validation present model using phenotypic frailty secondly add biomarkers environmental psychological factors prediction model