Liliane Mpabanzi, Jessica Wainwright, Bas Boonen, Hans van Eijk, Dipok Dhar, Esther Karssemeijer, Cees H C Dejong, Rajiv Jalan, Jean-Marc Schwartz, Steven W M Olde Damink, Zita Soons
Fluxomics reveals cellular and molecular basis of increased renal ammoniagenesis
NPJ systems biology and applications
populations ageing globally low middleincome countries lmics experiencing fastest rates demographic change studies explored burden frailty amongst older people hospital lmics healthcare services rapidly adapt align needs older people study aimed measure prevalence frailty amongst older people admitted hospital tanzania explore demographic clinical characteristics study prospective observational design sixmonth period adults 60 years old admitted medical wards four hospitals northern tanzania invited participate screened frailty using clinical frailty scale cfs frailty phenotype fp demographic clinical characteristics interest recorded structured questionnaire included barthel index identification elderly africans instrumental activities daily living iadeaiadl cognitive ideacog screens eurod depression scale confusion assessment method 540 adults aged 60 admitted 308 completed assessment frailty present 666 using cfs participants frailty significantly older lower levels education literacy greater disability greater comorbidity poorer cognition higher levels delirium using fp 570 participants classed frail though majority participants n 159 516 could classified due high proportion missing data study indicates prevalence frailty medical wards northern tanzania high according cfs however challenges operationalising fp setting highlight need future work adapt frailty screening tools african context future investigations also seek correlate frailty status longterm clinical outcomes admission setting