Robert Pratt|Nicola Robinson|Heather Loveday|Carol Pellowe|Peter J. Franks|Matthew Hankins|Clive Loveday
Adherence to Antiretroviral Therapy: Appropriate Use of Self-Reporting in Clinical Practice
University of West London|University of West London|University of West London|University of West London|University of West London|St. George's School|The King's College|University College London|The Royal Free Hospital
study investigated factors may affect adherence antiretroviral therapy people hiv infection compared use three selfreport tools determine client adherencea descriptive crosssectional study 260 hivinfected clients attending nine hiv outpatient centers england conducted using researcheradministered instruments selfreports adherence assessed using morisky medication adherence scale mmas reported adherence medication scale ram patient adjustment medication scale pamunivariate analysis clients selfreports indicated number associations adherence significant associations less adherent behavior identified two selfreport tools reported use recreational drugs p 001 living alone p 041 feeling depressed p 02 influenced media p 037 lack close confidant p 037 greater adherence associated clients reporting positive mental attitude hiv infection p 038 principal component analysis pca selfreport tool identified two wellrecognized constructs intentional nonadherence unintentional nonadherence addition third construct following instructions identified pam scale developed authors subsequent regression analysis failed confirm associations adherence suggested univariate analysisthis study suggests design use selfreport tools identify clients adherence complex antiretroviral regimens may need measure individual constructs adherence accurately assess adherence behavior