Femke De Meester, Delfien Van Dyck, Ilse De Bourdeaudhuij, Greet Cardon
Parental perceived neighborhood attributes: associations with active transport and physical activity among 10-12 year old children and the mediating role of independent mobility
BMC public health
skin tension plays pivotal role clinical settings affects scarring wound healing skin necrosis despite importance widely accepted method assessing vivo skin tension natural prestretch study aims utilise modern machine learning ml methods develop model uses noninvasive measurements surface wave speed predict clinically useful skin properties stress natural prestretch large dataset consisting simulated wave propagation experiments created using simplified twodimensional finite element fe model using dataset sensitivity analysis performed highlighting effect material parameters material model rayleigh supersonic shear wave speeds gaussian process regression model trained solve illposed inverse problem predicting stress prestretch skin using measurements surface wave speed model good predictive performance r2 09570 possible interpolate simplified parametric equations calculate stress prestretch demonstrate wave speed measurements could obtained cheaply easily simple experiment devised obtain wave speed measurements synthetic skin different values prestretch experimental wave speeds agree well fe simulations model trained solely fe data provided accurate predictions synthetic skin stiffness simulated experimental results provide evidence elastic wave measurements coupled ml models viable noninvasive method determine vivo skin tension statement significance prevent unfavourable patient outcomes reconstructive surgery necessary determine relevant subjectspecific skin properties example skin graft necessary estimate prestretch skin account shrinkage upon excision existing methods invasive rely experience clinician work aims present innovative framework noninvasively determine vivo material properties using speed surface wave travelling skin findings implications planning surgical procedures provides motivation use elastic wave measurements determine vivo material properties