Jeanie L.Y. Cheong|Peter J. Anderson|Gehan Roberts|Alice Burnett|Katherine J. Lee|Deanne K. Thompson|Carly Molloy|Michelle Wilson?Ching|Alan Connelly|Marc L. Seal|Stephen J. Wood|Lex W. Doyle
Contribution of Brain Size to IQ and Educational Underperformance in Extremely Preterm Adolescents
University of Melbourne|Murdoch Children's Research Institute|Royal Women's Hospital|Australian Psychological Society|University of Melbourne|Murdoch Children's Research Institute|Royal Children's Hospital|University of Melbourne|Murdoch Children's Research Institute|Australian Psychological Society|University of Melbourne|Murdoch Children's Research Institute|University of Melbourne|Murdoch Children's Research Institute|Florey Institute of Neuroscience and Mental Health|Murdoch Children's Research Institute|Murdoch Children's Research Institute|Murdoch Children's Research Institute|Florey Institute of Neuroscience and Mental Health|Murdoch Children's Research Institute|University of Melbourne|University of Birmingham|University of Melbourne|Murdoch Children's Research Institute|Royal Women's Hospital
extremely preterm ep survivors smaller brains lower iq worse educational achievement termborn peers contribution smaller brain size iq educational disadvantages ep unknown study aimed compare brain volumes multiple brain tissues structures epborn 28 weeks termborn 37 weeks control adolescents ii explore relationships brain tissue volumes iq basic educational skills whether differed group iii explore much total brain tissue volume explains underperformance ep adolescents compared controlslongitudinal cohort study 148 ep 132 term controls born victoria australia 199192 age 18 magnetic resonance imagingdetermined brain volumes multiple tissues structures calculated iq educational skills measured using wechsler abbreviated scale intelligence wasi wide range achievement testwrat4 respectivelybrain volumes smaller ep adolescents compared controls mean difference 95 confidence interval 59 80 37 total brain tissue volume largest relative differences noted thalamus hippocampus ep group lower iqs119 154 85 spelling80 115 46 math computation103 137 69 word reading56 88 24 scores controls pvalues0001 volumes total brain tissue brain tissues structures correlated positively iq educational skills relationship similar ep controls total brain tissue volume explained 2040 iq educational outcome differences ep controlsep adolescents smaller brain volumes lower iqs poorer educational performance controls brain volumes multiple tissues structures related iq educational outcomes smaller total brain tissue volume important contributor cognitive educational underperformance adolescents born ep