Olayinka Omigbodun, Cornelius Ani
A postgraduate training programme in child and adolescent mental health in a lower-middle-income country: a partnership model from Nigeria
BJPsych international
hypertension estimated cause 45 current global disease burden prevalent many developing countries developed world blood pressureinduced cardiovascular risk rises continuously across whole blood pressure range countries vary widely capacity management hypertension worldwide majority diagnosed hypertensives inadequately controlled statement addresses ascertainment overall cardiovascular risk establish thresholds initiation goals treatment appropriate treatment strategies nondrug drug therapies costeffectiveness treatmentsince publication whoish guidelines management hypertension 1999 evidence become available support systolic blood pressure threshold 140 mmhg even lowrisk patients highrisk patients evidence lower thresholds lifestyle modification recommended individuals evidence specific agents benefits patients particular compelling indications monotherapy inadequate majority patients patients without compelling indication particular drug class basis comparative trial data availability cost low dose diuretic considered initiation therapy places thiazide diuretic cheapest option thus cost effective compelling indications classes provide additional benefits even expensive may cost effective highrisk patients attain large benefits treatment expensive drugs may cost effective lowrisk patients treatment may costeffective unless drugs cheap