Adedayo O Joseph, Adeseye M Akinsete, Azeezat O Ajose, Aishat T Oladipo, Adeola Maliki, Korede Akindele, Michelle Mangongolo, Samuel Adeneye, Wilfred Ngwa
Increasing pediatric radiation oncology capacity in sub-saharan Africa using technology: a pilot of a pediatric radiation oncology virtual training course
BMC medical education
highrisk human papillomavirus hrhpv infection primary reason cervical cancer precancerous lesions females specific immune alterations pregnancy led greater hrhpv replication reduced clearance hrhpv infection study retrospectively obtained analyzed data tertiary hospital beijing china aimed ascertain genotype distribution prevalence hrhpv pregnant females moreover sought analyze association hrhpv maternalfetal pregnancy outcomes retrospective observational cohort study divided two parts part evaluated genotype distribution prevalence hrhpv encompassed 6285 pregnant women underwent routine pregnancy checkup thin prep cytology test tct hrhpv diagnosis weeks 1214 gestation january 1 2013 december 31 2021 part ii analyzed association hrhpv infection maternalfetal pregnancy outcome nearestneighbor 11 propensity score matching psm matched hrhpvpositive hrhpvnegative pregnant women using caliper width equal 002 psm 171 hrhpvpositive 171 hrhpvnegative pregnant women included analyze association hrhpv infection maternalfetal pregnancy outcome total 737 1173 pregnant women hrhpv positive five common genotypes hrhpv hpv52 290 hpv58 2 hpv16 194 hpv51 138 hpv39 129 agespecific hpv prevalence ushaped pattern observed first second peaks detected pregnant females aged 25 years aged 35 years respectively study found significant difference hrhpvpositive hrhpvnegative pregnant females following maternalfetal pregnancy outcomes spontaneous abortion 12 hrhpv positive 0 hrhpv negative p 0478 preterm delivery 47 hrhpv positive 53 hrhpv negative p 0804 premature rupture membrane 288 hrhpv positive 228 hrhpv negative p 0216 preeclampsia 76 hrhpv positive 76 hrhpv negative p 1 oligohydramnios 82 hrhpv positive 7 hrhpv negative p 0683 fetal growth restriction 18 hrhpv positive 06 hpv negative p 0615 placenta previa 12 hrhpv positive 06 hrhpv negative p 1 postpartum hemorrhage 89 hrhpv positive 112 hrhpv negative p 047 also significant difference delivery mode birth weight two groups hpv16 52 58 prevalent infection genotypes pregnant females study showed significant differences hrhpvpositive hrhpvnegative groups maternalfetal pregnancy outcomes