Cynthia F Wright, Laura M Kasman, Donita L Robinson, Gregory B Carey, Joshua D Hall, Joyce A Lloyd, Rita Shiang, Edward J Smith, Katherine L Wilson
A Multi-Institutional Description of Processes and Outcomes of Postbaccalaureate Research Education Programs in the Mid-Atlantic Region
Academic medicine : journal of the Association of American Medical Colleges
brucellosis commonest zoonotic disease worldwide common public health problem nepal highly variable clinical presentation nonspecific manifestations remains big challenge clinicians developing countries brucellosis tropism reticuloendothelial system liver frequently involved paucity data laboratory clinical findings human brucellosis nepal address knowledge gap conducted study find clinical profile biochemical abnormalities patients brucellosis tertiarycare teaching hospital western nepal crosssectional study carried gandaki medical college teaching hospital pokhara nepal patients admitted inpatient department hospital probable definitive diagnoses brucellosis included excluded consent participation study 18 years age deranged liver function due preexisting illnesses descriptive statistics used analyze data terms demography clinical manifestations laboratory parameters total 40 confirmed cases brucellosis age 1866 years study period half 55 n 22 study participants males lived rural setting 775 n 31 70 n 28 gave history ingestion highrisk food commonest clinical findings fever without chills 90 n 36 followed nauseavomiting 725 n 29 headache 40 n 16 malaise 375 n 15 liver function deranged majority patients common parameters alkaline phosphatase 96 n 38 cases followed sgot 625 n 25 leukocytosis 575 n 23 total bilirubin 525 n 21 sgpt 375 n 15 characteristic increment two folds upper limit normal observed alkaline phosphatase reticuloendothelial system frequently involved brucellosis notable changes observed liver function hematological parameters majority participants study findings highlight need implementation effective control programs address problem nepalese context