Andrew Goodwin|David A. Rice|Kit N. Simpson|Dee W. Ford
Frequency, Cost, and Risk Factors of Readmissions Among Severe Sepsis Survivors*
Medical University of South Carolina|Medical University of South Carolina|Medical University of South Carolina|Medical University of South Carolina
objective determine frequency mortality cost risk factors associated readmission index hospitalization severe sepsis design observational cohort study healthcare cost utilization project data setting nonfederal hospitals three us states patients severe sepsis survivors n 43452 first two quarters 2011 interventions none measurements main results measured readmission rates associated cost mortality readmissions severe sepsis survivors used multivariable logistic regression identify patient hospitalization characteristics associated readmission 43452 sepsis survivors 26 required readmission within 30 days 48 within 180 days cumulative mortality rate sepsis survivors attributed readmissions 8 estimated cost 11 billion among survivors 25 required multiple readmissions within 180 days accounted 77 readmissions age younger 80 years odds ratio 114 95 ci 108121 black race odds ratio 118 95 ci 110126 medicare medicaid payor status odds ratio 121 95 ci 113130 odds ratio 134 95 ci 123146 respectively associated greater odds 30day readmission female gender associated reduced odds odds ratio 092 95 ci 087096 comorbidities including malignancy odds ratio 134 95 ci 124145 collagen vascular disease odds ratio 130 95 ci 115146 chronic kidney disease odds ratio 124 95 ci 118131 liver disease odds ratio 122 95 ci 111134 congestive heart failure odds ratio 114 95 ci 108119 lung disease odds ratio 112 95 ci 106118 diabetes odds ratio 112 95 ci 107117 associated greater odds 30day readmission index hospitalization characteristics including longer length stay discharge care facility higher hospital annual severe sepsis case volume higher hospital sepsis mortality rate also positively associated readmission rates conclusion 30day 180day readmissions common sepsis survivors significant resultant cost mortality patient sociodemographics comorbidities well index hospitalization characteristics associated 30day readmission rates