Anthony J. Krafnick|D. Lynn Flowers|Megan M. Luetje|Eileen M. Napoliello|Guinevere F. Eden
An Investigation into the Origin of Anatomical Differences in Dyslexia
Georgetown University Medical Center|Georgetown University|Atrium Health Wake Forest Baptist|Georgetown University Medical Center|Georgetown University|Georgetown University Medical Center|Georgetown University|Georgetown University Medical Center|Georgetown University|Georgetown University Medical Center|Georgetown University
studies converged findings relatively less gray matter volume gmv developmental dyslexia bilateral temporoparietal left occipitotemporal cortical regions however interpretation results difficult reported neuroanatomical differences dyslexia may causal reading problems following example neural migration errors occurred early human development learning read alternatively less gmv may represent consequence impoverished reading experience akin experiencedependent gmv differences attributed illiterate compared literate adults likely combination factors driving observations attempt disambiguate influences using reading levelmatched design dyslexic children contrasted agematched controls also younger controls read level dyslexics consistent previous reports dyslexics showed less gmv multiple left right hemisphere regions including left superior temporal sulcus compared agematched controls however differences emerged dyslexics compared controls matched reading abilities right precentral gyrus gmv surviving second analysis similar analyses performed white matter volume regions emerged comparisons results indicate gmv differences dyslexia reported prior studies large part outcome experience eg disordered reading experience compared controls fraction differences driven dyslexia per se