Pamela Naidoo|Karl Peltzer|Julia Louw|Gladys Matseke|Gugu Mchunu|Bomkazi Tutshana
Predictors of tuberculosis (TB) and antiretroviral (ARV) medication non-adherence in public primary care patients in South Africa: a cross sectional study
Human Sciences Research Council|Human Sciences Research Council|Human Sciences Research Council|Human Sciences Research Council|University of KwaZulu-Natal|Human Sciences Research Council
despite downward trend absolute number tuberculosis tb cases since 2006 fall incidence rates since 2001 burden disease caused tb remains global health challenge coinfection tb hiv adds disease burden tb completely curable intake strict antitb drug treatment regimen requires extremely high consistent level adherencethe aim study investigate factors associated adherence antitb hiv treatment drugsa crosssectional survey method used three study districts 14 primary health care facilities selected basis highest tb caseload per clinic new tb new tb retreatment patients consecutively screened within one month antituberculosis treatment sample comprised 3107 tb patients treatment least three weeks subsample total sample antitb treatment antiretroviral therapyart n 757 data collection tools included sociodemographic questionnaire posttraumaticstressdisorder ptsd screen psychological distress scale alcohol use disorder identification test audit selfreport measures tobacco use perceived health status adherence antitb drugs artthe majority participants n 3107 new tb cases 559 hiv coinfection rate adult male female sample 18 years older significant predictors nonadherence common antitb drugs dual therapy art antitb drugs included poverty one comorbid health condition high risk alcohol misuse partner hiv positive additional predictor nonadherence antitb drugs tobacco usea comprehensive treatment programme addressing poverty alcohol misuse tobacco use psychosocial counseling indicated tb patients without hiv treatment care package needs involve health sector relevant government sectors social development