Andrea Messori, Valeria Fadda, Melania Rivano, Sabrina Trippoli
Mitraclip Versus Medical Therapy or Surgery in Patients With Mitral Regurgitation: Long-Term Outcomes Determined by the Reconstruction of Individual Patient Data
Cureus
fatigue prevalent across wide range medical conditions debilitating distressing likely fatigue experienced differently according underlying aetiology poorly understood digital health technologies present promising approach give new insights fatiguethe aim study use digital health technologies realtime selfreports qualitative interview data investigate fatigue experienced time participants myeloma long covid heart failure controls without problematic fatigue objectives understand sensed parameters add value characterisation fatigue determine whether study processes feasible acceptable scalable ecological momentary assessment study carried 2 4 weeks participant defined individuals fatigue relating myeloma n10 heart failure n10 long covid n10 controls without problematic fatigue study condition n10 recruited ecg patches measure heart rate variability respiratory rate body temperature activity posture wearable bracelet accompanied environment beacons measure physical activity sleep room location within home selfreports mental physical fatigue collected via smartphone app four times daily ondemand validated fatigue affect questionnaires completed baseline 2 weeks endofstudy interviews investigate experiences fatigue study participation feedback session offered participants discuss datadata analysed using multilevel modelling machine learning interviews feedback sessions analysed using content thematic analyses study approved east englandcambridge east research ethics committee 22ee0261 results disseminated peerreviewed journals international conferences nct05622669