Luka Johanna Debbeler, Anne Pohrt, Carolin Fleischmann-Struzek, Daniel Schwarzkopf, Sebastian Born, Konrad Reinhart, Odette Wegwarth
Text-Based vs. Graphical Information Formats in Sepsis Prevention and Early Detection: A Randomized Controlled Trial on Informed Choice
Journal of clinical medicine
malaria risk factors household level known complex uncertain stochastic nonlinear multidimensional interplay among factors makes targeted interventions resource allocation malaria control challenging however studies demonstrated malarias transmission complexity control integrated modelling available evidence ugandas refugee settlements using 20182019 ugandas malaria indicator survey umis data alternative bayesian belief network bbn modelling approach used analyse predict rank illustrate conceptual reasoning complex causal relationships among risk factors malaria infections among children underfive refugee settlements uganda umis household level information obtained using standardized questionnaires total 675 children 5 years tested malaria dataset casefile containing malaria test results demographic socialeconomic environmental information created casefile divided training 80 n 540 testing 20 n 135 datasets training dataset used develop bbn model following well established guidelines testing dataset used evaluate model performance model accuracy 9111 area receiveroperating characteristic curve 095 models spherical payoff 091 logarithmic quadratic losses 036 016 respectively indicating strong predictive classification ability model probability refugee children testing positive negative malaria 481 519 respectively top ranked malaria risk factors based sensitivity analysis included 1 age child 2 roof materials ie thatch roofs 3 wall materials ie poles mud thatch walls 4 whether children sleep insecticidetreated nets 5 type toilet facility used ie toilet facility pit latrines slabs 6 walk time distance water sources 0 10 min 7 drinking water sources ie open water sources piped water premises ranking rather statistical significance malaria risk factors crucial approach applied research helps stakeholders determine allocate resources targeted malaria interventions within constraints limited funding refugee settlements