Xinxin Xu, Safdar Husain Tahir, Khuda Bakhsh Khan, Mushtaq A Sajid, Muhammad Azhaf Safdar
Beyond regression: Unpacking research of human complex systems with qualitative comparative analysis
Heliyon
advancements medical treatments resulted increased medical costs cancer patients half patients advanced lung cancer reported unmet financial needs purpose study examine differences prevalence correlates financial hardship middle olderaged patients advanced lung cancer impact multiple healthrelated outcomes study presents crosssectional analysis involving 226 patients advanced lung cancer enrolled randomized controlled trial conducted 2018 2020 data collection performed selfreported questionnaires electronic medical records multivariable logistic linear regression models adopted analysis 580 reported experiencing financial hardships middleaged participants single lower education level likely experience financial difficulties however males higher performance status associated lower likelihood experiencing financial difficulties among olderaged participants financial hardship significantly associated anxiety p 0001 depression p 0001 sleep disturbances p 0001 quality life global health status p 0002 functional scale score p 0001 symptom scale score p 0001 lung cancerspecific scale score p 0001 half patients advanced lung cancer experienced financial hardships caused cancer treatment higher prevalence reported middleaged patients different sociodemographic clinical variables correlated financial hardship middle olderaged participants respectively attention paid middleaged patients advanced lung cancer particularly routine assessments