Karina Lovell|Peter Bower|David Richards|Michael Barkham|Bonnie Sibbald|Chris Roberts|Linda Davies|Anne Rogers|Judith Gellatly|Sue Hennessy
Developing guided self-help for depression using the Medical Research Council complex interventions framework: a description of the modelling phase and results of an exploratory randomised controlled trial
University of Manchester|National Computing Centre (United Kingdom)|University of Manchester|University of Exeter|University of Sheffield|National Computing Centre (United Kingdom)|University of Manchester|University of Manchester|University of Manchester|University of Manchester|University of Manchester|University of York
current guidelines management depression suggest use guided selfhelp patients mild moderate disorders however little consensus concerning optimal form delivery intervention develop acceptable effective interventions phased process proposed using modelling phase examine develop intervention prior preliminary testing exploratory trial paper describes modelling phase used develop guided selfhelp intervention depression primary care b reports data exploratory randomised trial intervention guided selfhelp intervention developed following modelling phase involved systematic review meta synthesis consensus process intervention tested exploratory randomised controlled trial examining fidelity using analysis taped guided selfhelp sessions b acceptability patients professionals qualitative interviews c effectiveness estimation intervention effect size fifty eight patients recruited exploratory trial seven professionals nine patients interviewed 22 tapes sessions analysed fidelity generally fidelity intervention protocol high professionals delivered majority specific components exception use feedback acceptability professionals patients also high effect size intervention outcomes small line previous analyses showing modest effect guided selfhelp primary care however sample size small confidence intervals around effectiveness estimate wide general principles modelling phase adopted study designed draw range evidence potentially providing intervention evidencebased patientcentred acceptable professionals however pilot outcome data suggest intervention developed particularly effective advantages disadvantages general methods used modelling phase discussed possible reasons failure demonstrate larger effect particular case outlined