Muhammad Mudassar Bilal, Syed Bilal Shah, Tanzeel Ur Rehman, Noman Sadiq, Ghulam Rehmani Lakho
Knowledge, attitude, and awareness of cardiopulmonary resuscitation among university enrolled medical and non-medical students of Pakistan: An online study
Pakistan journal of medical sciences
antidepressants firstline treatment depression yet many patients respond need understand patients greater treatment response little research patient characteristics moderate effectiveness antidepressants study examined potential moderators response antidepressant treatment panda trial investigated clinical effectiveness sertraline n 326 compared placebo n 329 primary care patients depressive symptoms investigated 11 potential moderators treatment effect age employment suicidal ideation marital status financial difficulty education social support family history depression life events health past antidepressant use using multiple linear regression investigated appropriate interaction term potential moderators treatment allocated family history depression variable weak evidence effect modification pvalue interaction 0048 family history depression may greater benefit antidepressant treatment found evidence effect modification pvalue interactions029 ten variables evidence treatment moderators extremely limited supporting approach continuing discuss antidepressant treatment patients presenting moderate severe depressive symptoms