Kamalika Mojumdar|Madhu Vajpayee|Neeraj Chauhan|Sanjay Mendiratta
Late presenters to HIV care and treatment, identification of associated risk factors in HIV-1 infected Indian population
All India Institute of Medical Sciences|All India Institute of Medical Sciences|All India Institute of Medical Sciences|All India Institute of Medical Sciences
abstract background timely access antiretroviral therapy key controlling hiv infection late diagnosis presentation care diminish benefits antiretrovirals increase risk transmission aimed identify late presenters patients sent first cd4 cell count hiv diagnosis therapy initiation evaluation aimed identifying patient factors associated higher risk late presentation methods retrospective data collection analysis done 3680 subjects visiting laboratory cd4 cell counts 2001 2007 segregated patients basis cd4 cell counts first hiv diagnosis factors associated risk late presentation cd4 cell counts hiv diagnosis identified using univariate analysis strength association individual factor assessed calculation odds ratios results 3680 subjects 2936 8337 defined late presenters late testing varied among age groups transmission categories gender males twice likely present late compared females found significant positive association heterosexual transmission route p lt 0001 older age groups 45 years p 00004 late presentation female sex children 14 years age sexual contact hiv positive spouse associated significantly lower risks presenting late intravenous drug users also associated lower risks late presentation comparison heterosexual transmission route conclusions study identifies hiv infected population groups higher risk late presentation care treatment risk factors identified associated late presentation utilised formulating targeted public health interventions order improve early hiv diagnosis