Cayla Price, Deborah Cohen, Peter Pribis, Jean Cerami
Nutrition Education and Body Mass Index in Grades K-12: A Systematic Review
The Journal of school health
investigate phenotype autistic children tuberous sclerosis complex tsc specifically autism spectrum disorder asd severity characteristics intellectual ability adaptive executive function language skills attentiondeficithyperactivity disorder features internalizing externalizing behaviours medline embase cochrane library searched march 2021 studies investigated predefined phenotypic factors children tscasd included according preferred reporting items systematic review metaanalysis protocols prismap guidelines two authors independently reviewed titles abstracts full texts extracted data risk bias grade assessments completed thirtyfour studies 3160 children tsc 30 asd included metaanalysis found 90 95 confidence interval 8694 children tscasd intellectual disability evidence suggest young children tscasd idiopathic asd similar pattern severity behaviour overall data phenotypic characteristics limited greater proportion children tscasd reported intellectual disability children idiopathic asd early intervention consider needs children high likelihood intellectual disability research needed better understand impacts intellectual disability cooccurring difficulties adaptive function participation quality life tscasd children tuberous sclerosis complex tsc autism spectrum disorder asd intellectual disability tscasd early intervention planning consider high likelihood intellectual disability quality life functional impact intellectual disability tscasd understood little known cooccurring difficulties tscasd