Edmond L. Paquette|Roger R. Connelly|Isabell A. Sesterhenn|Wei Zhang|Leon Sun|Laurence R. Paquette|Renata Greenspan|David G. McLeod|Judd W. Moul
Improvements in pathologic staging for African-American men undergoing radical retropubic prostatectomy during the prostate specific antigen era
Armed Forces Institute of Pathology|Armed Forces Institute of Pathology|Uniformed Services University of the Health Sciences|Walter Reed Army Institute of Research|Uniformed Services University of the Health Sciences|Uniformed Services University of the Health Sciences|Walter Reed Army Institute of Research
background objective compare changes pathologic clinical data time africanamerican aa white men prostate carcinoma undergoing radical prostatectomy attempt determine early impact prostate specific antigen psa methods data 195 aa 587 white men underwent radical prostatectomy 1988 1999 equal access tertiary military medical facility collected statistical analysis used determine significance changes rates extracapsular extension ece positive margins pretreatment psa levels age time surgery race time results comparing 198899 results authors found percentage aa men ece decreased 100 348 p 0007 white men 569 432 p 0269 percentage aa men positive margins decreased 100 261 p 00001 white men 412 270 p 0021 mean age surgery decreased 666 599 years aa men p 0001 659 611 years white men p 0001 also psa levels decreased 101 66 ngdl white men p 0001 165 65 ngdl aa men p 0001 conclusions authors believe decrease ece positive margins aa men primarily psa testing coupled improved public awareness equal access care appears reasonable recommend psa testing aa men historically experienced poor outcomes prostate carcinoma cancer 20019226739 2001 american cancer society