Yukiko Nishihama, Shoji F Nakayama, Tomohiko Isobe, Michihiro Kamijima
Association between maternal urinary neonicotinoid concentrations and child development in the Japan Environment and Children's Study
Environment international
little evidence dietary supplements beneficial patients breast cancer therefore usually recommended treatment guidelines aim present analysis assess prevalence dietary supplement ds intake among women breast cancer diagnosis participants success c lifestyle intervention study randomized controlled trial women newly diagnosed intermediate highrisk breast cancer completed two questionnaires dietary supplement intake 24 months qs1 48 months qs2 beginning lifestyle intervention study registered 12172008 eu clinical trials register httpswwwclinicaltrialsregistereu trial registration number 200800545338 questionnaires collected data ds intake 5year period prediagnosis qs1 period postdiagnosis qs2 multivariate logistic regression models fitted examine differences ds intake two intervention groups groups pooled examine differences ds use prediagnostic postdiagnostic period total 320 questionnaires 585 intervention group completers 416 questionnaires 466 lowlevel intervention group completers included analysis overall 202 respondents reported taking ds prior diagnosis cancer diagnosis percentage women taking ds significantly increased 564 p time effect 00001 differences ds intake intervention groups observed single combined preparations vitamins mineralstrace elements frequently reported supplements notably 9fold increase vitamin intake reported postdiagnosis proportion women increased 38 345 3fold increase reported intake dietary supplements seen women breast cancer diagnosis observations underscore need incorporate patient education surrounding use dietary supplements treatment care plan particularly addressing negligible benefits well potential risks treatment interactions