Vanessa L. Kronzer|Michelle R. Jerry|Arbi Ben Abdallah|Troy S. Wildes|Sherry McKinnon|Anshuman Sharma|Vanessa L. Kronzer
Changes in quality of life after elective surgery: an observational study comparing two measures
Washington University in St. Louis|SUNY Canton|University of Michigan–Ann Arbor|Washington University in St. Louis|Washington University in St. Louis|Washington University in St. Louis|Washington University in St. Louis|Washington University in St. Louis
main objective compare change validated quality life measure global assessment measure secondary objectives estimate minimum clinically important difference mcid describe change quality life surgical specialtythis prospective cohort study included 7902 adult patients undergoing elective surgery changes veterans rand 12item health survey vr12 composed physical component summary pcs mental component summary mcs calculated using preoperative postoperative questionnaires latter also contained global assessment question quality life compared pcs mcs global assessment using descriptive statistics weighted kappa mcid calculated using anchorbased approach analyses prespecified registered nct02771964by change vr12 scores equal proportion patients experienced improvement deterioration quality life 28 pcs 25 mcs contrast global assessment measure 61 reported improvement 10 reported deterioration agreement global assessment slight pcs kappa 020 57 matched mcs kappa 010 54 matched mcid overall vr12 score approximately 25 points patients undergoing orthopedic surgery showed improvement quality life measures patients undergoing gastrointestinalhepatobiliary urologic surgery showed deteriorationsubjective global quality life report agree well validated quality life instrument perhaps due patient overoptimism