Tatiana Toro?Ramos|Andreas Michaelides|Maria Anton|Zulekha Karim|Leah Kang-Oh|Charalambos Argyrou|Elisavet Loukaidou|Marina Charitou|Wilson Sze|Joshua D. Miller
Mobile Delivery of the Diabetes Prevention Program in People With Prediabetes: Randomized Controlled Trial
Noom (United States)|Noom (United States)|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University|Stony Brook School|Stony Brook University
background centers disease control prevention cdc diabetes prevention program dpp formed foundation type 2 diabetes mellitus t2dm prevention efforts lifestyle change modifications multiple care settings knowledge randomized controlled trial verified efficacy fully mobile version cdcs diabetes prevention program dpp objective study aimed investigate longterm weight loss glycemic efficacy mobiledelivered dpp compared control group receiving usual medical care methods adults prediabetes n202 recruited clinic randomized either mobiledelivered coachguided dpp noom control group received regular medical care including paperbased dpp curriculum formal intervention intervention group learned use noom program interact coach importance maintaining motivation access interactive coachtoparticipant interface group messaging daily challenges behavior change dppbased education articles food logging automated feedback primary outcomes included changes weight hemoglobin a1c hba1c levels 6 12 months respectively exploratory secondary outcomes included program engagement predictor changes weight hba1c levels results total 202 participants recruited randomized intervention n101 control group n99 intentiontotreat itt analyses changes participants weight bmi significantly different 6 months intervention control groups difference hba1c levels mean difference 0004 se 005 p94 weight bmi lower intervention group 264 kg se 071 plt001 099 kgm2 se 029 p001 respectively differences persisted 12 months however analyses involve itt program completers achieved significant weight loss 56 se 081 plt001 6 months maintaining 47 se 088 plt001 weight loss 12 months control group lost 015 6 months se 064 p85 gained 033 se 070 p63 12 months randomized intervention group start program meaningful weight hba1c level change similar control group 1 year intervention group showed 023 reduction hba1c levels completed intervention showed 028 reduction assigned control group 016 reduction hba1c levels conclusions novel mobiledelivered dpp achieved significant weight loss reductions 1 year compared usual care type intervention reduces risk overt diabetes without added barriers inperson interventions trial registration clinicaltrialsgov nct03865342 httpsclinicaltrialsgovct2shownct03865342