Kirsten E Lyke, Joel V Chua, Michael Koren, Heather Friberg, Gregory D Gromowski, Rekha R Rapaka, Adam T Waickman, Sudhaunshu Joshi, Kathleen Strauss, Michael K McCracken, Hernando Gutierrez-Barbosa, Biraj Shrestha, Christopher Culbertson, Paula Bernal, Rafael A De La Barrera, Jeffrey R Currier, Richard G Jarman, Robert Edelman
Efficacy and immunogenicity following dengue virus-1 human challenge after a tetravalent prime-boost dengue vaccine regimen: an open-label, phase 1 trial
The Lancet. Infectious diseases
40 years african swine fever asf endemic sardinia historically areas higher risk located throughout inland parts island domestic pigs still illegally kept semiwild conditions living contact local wild boar population thereby creating perfect conditions disease endemicity new eradication plan epasf1518 ongoing past 3 years based comprehensive strategy adapted local situation focused strong actions domestic pig farms wild boars wb third sardinian typical involved population illegal freeranging pigs frps fundamental aspect plan classification pig farms controlled certified based clinical structural biosecurity characteristics eradication plan also provides strong action illegal farms pig meat marketing channels addition plan establishes specific control measures wb hunting asf checks control strategy specifically based municipality risk level focus actions resources areas higher risk endemic reemerging asf thus precise risk classification fundamental goal aim present work establish asf risk index provide summary measure risk level sardinian municipalities synthetic measure express different aspects multidimensional phenomenon single numerical value facilitating territorial temporal comparisons end retrospective data years 20112018 used asf risk index result algorithmic combination numerical elementary indicators disease prevalence suid populations wb compliance epasf1518 domestic pig compliance epasf1518 presence frps negative binomial regression model applied predictors calculated obtain risk index municipality result risk analysis discussed considered according expert opinion consensus results study expressed risk score classified five risk levels used help define actions carried sardinian municipality according risk assessment territory