Sahil S Shet, Ben Murphy, Sinead Boran, Colm Taylor
Readability of Online Information for Parents Concerning Paediatric In-Toeing: An Analysis of the Most Popular Online Public Sources
Cureus
dinuclear copper complexes designed molecular recognition order selectively bind two neighboring phosphate moieties backbone double strand dna associated biophysical biochemical cytotoxic effects dna investigated previous works atomic force microscopy afm ambient conditions turned particular valuable asset since complexes influence macromechanical properties configurations strands investigate scrutinize effects depth structural point view cuttingedge preparation methods scanning force microscopy ultrahigh vacuum uhv conditions employed yield submolecular resolution images dna strand mechanics interactions could resolved single base pair level including amplified formation melting bubbles even interaction singular complex molecules could observed better assess results appearance treated dna also compared behavior untreated dna uhv different substrates finally present data statistical simulation reasoning nanomechanics strand dissociation sort quantitative experimental insights paralleled statistical simulations impressively shade light rationale strand dissociations novel dna interaction process important nanomechanistic key novel approach development new chemotherapeutic agents