Susan Humphreys, Britta S von Ungern-Sternberg, Fiona Taverner, Andrew Davidson, Justin Skowno, Ben Hallett, David Sommerfield, Neil Hauser, Tara Williams, Susan Spall, Trang Pham, Tiffany Atkins, Mark Jones, Emma King, Laura Burgoyne, Philip Stephens, Shyan Vijayasekaran, Nicola Slee, Hannah Burns, Donna Franklin, Judith Hough, Andreas Schibler
High-flow nasal oxygen for children's airway surgery to reduce hypoxaemic events: a randomised controlled trial
The Lancet. Respiratory medicine
evidence suggests link polyphenol intake reduced incidence several chronic diseases could arise associations polyphenol intake reduced systemic oxidative stress subsequent inflammation however confirming association difficult large cohorts allow comprehensive assessments polyphenol intake markers systemic inflammation address polyphenol intake assessed ukbased airwave cohort using 7d diet diaries data phenolexplorer test associations polyphenol intake blood biomarkers inflammation participants included 9008 males females aged 1774 median age 42 whose data included crosssectional analysis phenolexplorer used estimate individuals polyphenol intake diet data describing consumption 4104 unique food items creactive protein crp fibrinogen used blood biomarkers inflammation 448 polyphenols found reported diet items median total polyphenol intake 1536 mgd 10582092 mgd phenolic acids flavonoids main types polyphenols nonalcoholic beverages vegetables fruit primary sources variation energyadjusted polyphenol intake explained age sex salary body mass index education level smoking alcohol consumption linear regressions showed inverse associations total daily intake crp 000702 p 0001 fibrinogen 000221 p 0038 associations specific polyphenol compound groups also found logistic regressions using total polyphenol intake quartiles showed stepwise reductions odds elevated crp higher intake 6 23 24 compared quartile 1 p 0003 alongside 3 7 lower odds per unit polyphenol consumption equivalent 1 cup tea coffee per day study describes polyphenol intake large contemporary uk cohort observed associations higher intake lower crp fibrinogen contributes evidence supporting health benefits dietary polyphenols