Jennifer L. Moss|Zaria Tatalovich|Li Zhu|Camille Morgan|Kathleen A. Cronin
Triple-negative breast cancer incidence in the United States: ecological correlations with area-level sociodemographics, healthcare, and health behaviors
National Cancer Institute|National Cancer Institute|National Cancer Institute|National Cancer Institute|Center for Global Health|National Cancer Institute
triplenegative breast cancer tnbc aggressive subtype breast cancer commonly diagnosed among black women subgroups tnbc varies geographically little known arealevel characteristics associated elevated incidencewe generated 20112013 ageadjusted tnbc incidence rates state economic areas seas 43 states using data north american association central cancer registries cases missing data molecular markers imputed tnbc status using crossmarginal proportions linked data sea covariates national sources using linear ecological regression examined correlates tnbc incidence rates overall population age 50 years 50 years race white blackspecific subgroupsthe mean annual incidence tnbc across seas 137 per 100000 women range 45263 especially high variable rates among african american women mean 205 range 001551 tnbc incidence highest south atlantic east south central census divisions lowest mountain division overall tnbc incidence associated sea sociodemographics eg percent females age 45 nonhispanic black coefficient estimate est 162 healthcare characteristics eg percent population without health insurance est 052 health behaviors eg prevalence obesity among women est 072 p 005 variables related tnbc incidence included density obstetriciangynecologists prevalence smokingtnbc incidence varied across seas us particularly african american women identifying areas elevated tnbc incidence facilitate research interventions area individuallevel correlates tnbc