Lauren E Smith, Mary E McBride, Bruce Henschen, Jennifer Bierman, Toshiko Uchida, Walter Eppich
Mechanisms of Near-Peer Learning in a Longitudinal Clerkship: A Grounded Theory Study
Academic medicine : journal of the Association of American Medical Colleges
high rates adverse moodneurodevelopmental traits seen multiple dermatological conditions significantly affect patient quality life understanding sexspecific nature magnitude impact basis traits lesserstudied conditions like ichthyosis important developing effective interventions quantify compare relevant psychological traits men xlinked ichthyosis xli n 54 xli carrier women n 83 patients ichthyosis vulgaris iv men n 23 women n 59 psoriasis men n 30 women n 122 identify factors selfreported contribute towards depressive anxious irritable phenotypes participants recruited via relevant charities social media completed online survey established questionnaires data analysed sex skin condition compared general population data compared general population higher rate lifetime prevalence mood disorder diagnoses across groups neurodevelopmental disorder diagnoses xli groups groups exhibited similarly significant elevations recent mood symptoms cohen statistic 095128 p 0001 neurodevelopmental traits 031091 p 005 compared general population controls selfreported moderate effects quality life stigmatization strong positive associations neurodevelopmental traits recent mood symptoms r 047 p 001 feelings stigmatization quality life particularly men numerous factors identified contributing significantly mood symptoms condition sexspecific condition sexindependent manner found individuals xli iv psoriasis show higher levels mood disorder diagnoses symptoms matched general population controls prevalence severity similar across conditions also identified number factors potentially conferring either general conditionspecific risk adverse mood symptoms three skin conditions could targeted clinically andor education programmes clinical practice recognizing moodneurodevelopmental problems ichthyosis psoriasis addressing predisposing factors identified study benefit mental health affected individuals