Alessandra Geraci, Anna Cantagallo
Inferential reasoning: comparison of patients with schizophrenia and patients with traumatic brain injury
Psychiatry research
pediatric severe sepsis pss associated increased mortality acute kidney injury aki independent risk factor mortality pss however little data impact aki hospital outcomes pss analyzed nonoverlapping years kids inpatient database kid national inpatient sample nis database 2003 2019 pediatric patients severe sepsis 1 18 years age using icd diagnosis codes patients divided two groups based aki status compared outcomes measures including inhospital mortality healthcare resource utilization using length stay inflationadjusted hospitalization charges analyzed 192712 hospitalizations due pss 17year period prevalence aki 236 overall increasing trend p0001 prevalence aki significantly increased patients diabetes mellitus organ transplantation hiv urinary tract anomalies malnutrition p0001 mortality rate significantly higher among patients aki 198 vs 81 p0001 pss aki significantly higher median length stay 14 vs 11 days total hospitalization charges 168106 vs 100906 p0001 multivariate logistic regression analysis showed aki without kidney replacement therapy krt associated 302 times increased odds mortality 95 ci 299317 p0001 requiring krt 64 times increased odds mortality 95ci 6167 p0001 aki without krt associated 77 95 ci 73805 additional days hospitalization 154536 95 ci 149500159572 additional us dollars hospitalization charges almost 1 4 hospitalizations pss aki associated 3 times increased risk mortality need krt adversely impacts mortality healthcare utilization higher resolution version graphical abstract available supplementary information