Chen-Wei Pan, Hua Zhong, Jun Li, Chen Suo, Pei Wang
Measuring health-related quality of life in elementary and secondary school students using the Chinese version of the EQ-5D-Y in rural China
BMC public health
evaluate impact rescheduling hydrocodone combination products hcps schedule iii controlled substances act restrictive schedule ii unintentional pediatric exposures 5 years old using us data outpatient retail pharmacy dispensing emergency department ed visits poison center pc exposure cases assessed trends prescriptions dispensed unintentional pediatric exposure cases involving hydrocodone rescheduled iii ii compared oxycodone schedule ii codeine schedule iii combination products using descriptive interrupted timeseries analyses 16 quarters october 2014 rescheduling hcps dispensing hydrocodone products declining rescheduling declined steeply postrescheduling analyses hydrocodone oxycodone significant slope decreases pc case rates post versus preperiod larger hydrocodone codeine small significant slope increase pc case rates estimated 4202 ed visits pediatric hydrocodone exposures occurred preperiod 2090 visits occurred postperiod significant decrease 503 oxycodone exposures showed significant decrease pediatric hydrocodone unintentional exposure ed visits pc cases decreased hcp rescheduling would expected prerescheduling trend continued acceleration decrease hydrocodone pc cases partially offset slowing decrease codeineinvolved cases trend changes likely due multiple factors including changes dispensing followed rescheduling unintentional pediatric medication exposures poisonings remain public health concern requiring ongoing multifaceted mitigation efforts