Nicole Amorim, Brito Irma, Fátima Guerra, Rute Lopes, Miguel Ricou
Parental perspectives on Children's lifestyles: A Path for school health promotion
Heliyon
childhood trauma may contribute poor lifelong health part programming hpaaxis response future life stressors date empirical evidence shows association childhood trauma dysregulation hpaaxis blunted cortisol reactivity acute stressors conduct initial examination childhood trauma moderator changes time perceived stress levels hpaaxis response major chronic stressor adulthood participants 83 maternal caregivers children newly diagnosed cancer completed childhood trauma questionnaire ctq year following childs cancer diagnosis hair samples collected 7 times assessment cortisol completed monthly measures perceived stress ctq scores expected range community sample associated changes perceived stress cortisol concentration time 003 p 002 0004 p 008 respectively independently age education treatment intensity randomization stress management intervention maternal caregivers endorsed lower childhood trauma showed steeper decline perceived stress larger increase cortisol levels across year caregivers recalled childhood trauma findings extend animal models studies examine cortisol reactivity acute stressors suggest childhood trauma may program phenotype psychologically reactive shows blunted hpaaxis response chronic stress adaptive shortterm early life programming may incur longterm costs health work warranted examine possibility