Laila M Kenawi, Haytham S Jaha, Mashael M Alzahrani, Jihan I Alharbi, Shahad F Alharbi, Taif A Almuqati, Rehab A Alsubhi, Wahdan M Elkwatehy
Cone-Beam Computed Tomography-Based Investigation of the Prevalence and Distribution of Pulp Stones and Their Relation to Local and Systemic Factors in the Makkah Population: A Cross-Sectional Study
Cureus
numerous studies indicated connection psychiatric symptoms specifically anxiety depression gastroesophageal reflux however precise nature link severity gastroesophageal reflux disease severity anxiety depression remains uncertain gathered 24h ph monitoring data baseline patient information cohort 518 individuals additionally evaluated psychological wellbeing using hospital anxiety depression scale relationship baseline characteristics varying degrees anxiety depression gastroesophageal reflux disease gerd assessed using r software version 413 logistic regression models findings indicate statistically significant variation anxiety levels based gender well significant disparity depression groups considering age literacy levels kruskalwallis test analysis revealed significant positive correlation severity anxiety depression 24h ph monitoring results patient cohort anxiety depression levels increased rank mean examination result also increased logistic regression modeling analysis showed higher anxiety level associated higher level gerd presence mild anxiety statistically significant association higher incidence gerd odds ratio 264 95 ci 150 464 similarly moderately severe anxiety group also exhibits causal relationship increased gerd incidence 684 95 ci 392 1217 additionally moderate severe depression associated higher incidence gerd 232 95 ci 123 437 prevalence gerd greater among males compared females 229 95 ci 151349 additionally elevated body mass index bmi demonstrated positive correlation susceptibility gerd 107 95 ci 101114 increasing age may promote occurrence gerd patients findings may help provide better basis psychological pharmacological interventions gerd patients psychosomatic symptoms future provide reference basis clinical treatment disease