YuNing Zhang, Yijie Dong, Zihan Mei, Yiqing Hou, Minyan Wei, Yat Hin Yeung, Jiale Xu, Qing Hua, LiMei Lai, Ning Li, ShuJun Xia, Chun Zhou, JianQiao Zhou
Performance of large language models on benign prostatic hyperplasia frequently asked questions
The Prostate
studies weightcontrol diets high protein low glycemic index reached varied conclusions probably owing fact studies insufficient powerwe enrolled overweight adults eight european countries lost least 8 initial body weight 33mj 800kcal lowcalorie diet participants randomly assigned twobytwo factorial design one five ad libitum diets prevent weight regain 26week period lowprotein lowglycemicindex diet lowprotein highglycemicindex diet highprotein lowglycemicindex diet highprotein highglycemicindex diet control dieta total 1209 adults screened mean age 41 years bodymass index weight kilograms divided square height meters 34 938 entered lowcaloriediet phase study total 773 participants completed phase randomly assigned one five maintenance diets 548 completed intervention 71 fewer participants highprotein lowglycemicindex groups lowproteinhighglycemicindex group dropped study 264 256 respectively vs 374 p002 p001 respective comparisons mean initial weight loss lowcalorie diet 110 kg analysis participants completed study lowproteinhighglycemicindex diet associated subsequent significant weight regain 167 kg 95 confidence interval ci 048 287 intentiontotreat analysis weight regain 093 kg less 95 ci 031 155 groups assigned highprotein diet assigned lowprotein diet p0003 095 kg less 95 ci 033 157 groups assigned lowglycemicindex diet assigned highglycemicindex diet p0003 analysis involving participants completed intervention produced similar results groups differ significantly respect dietrelated adverse eventsin large european study modest increase protein content modest reduction glycemic index led improvement study completion maintenance weight loss funded european commission clinicaltrialsgov number nct00390637