Kibruyisfaw Weldeab Abore, Estifanos Bekele Fole, Mahlet Tesfaye Abebe, Natnael Fikadu Tekle, Robel Bayou Tilahun, Fraol Daba Chinkey, Michael Teklehaimanot Abera
Adherence and factors influencing adherence to glaucoma medications among adult glaucoma patients in Ethiopia: A systematic review and meta-analysis
PloS one
early life growth longlasting metabolic behavioral consequences intervention period developmental plasticity may alter longterm obesity risk modifiable factors infancy identified recently preventive interventions tested intervention nurses starting infants growing healthy trajectories insight study longitudinal randomized controlled trial evaluating responsive parenting intervention designed primary prevention obesity parenting intervention compared home safety control among firstborn infants parents insights central hypothesis responsive parenting specifically responsive feeding promotes selfregulation shared parentchild responsibility feeding reducing subsequent risk overeating overweight316 firsttime mothers fullterm newborns enrolled one maternity ward two weeks following delivery dyads randomly assigned parenting safety groups subsequently research nurses conduct study visits groups consisting home visits infant age 34 16 28 40 weeks followed annual clinicbased visits 1 2 3 years groups receive intervention components framed around four behavior states sleeping fussy alert calm drowsy main study outcome bmi zscore age 3 years additional outcomes include related patterns infant weight gain infant sleep hygiene duration maternal responsiveness soothing strategies infanttoddler distress fussiness maternal feeding style infant dietary content physical activity maternal outcomes related weight status diet mental health parenting sense competence collected infant temperament explored moderator parenting effects blood collected obtain genetic predictors weight status finally secondborn siblings insight participants enrolled observationonly study explore parenting differences siblings effect weight outcomes carryover effects insight interventions subsequent siblingswith increasing evidence suggesting importance early life experiences longterm health trajectories insight trial ability inform future obesity prevention efforts clinical settingsnct01167270 registered 21 july 2010