Sowoo Park, Doosam Song, Young Min Jo, Ju-Hyeong Park, Tae Jeong Lee, Junemo Koo
Development of air purifier operation guidelines using grey box models for the concentrations of particulate matter in elementary school classrooms
Aerosol science and technology : the journal of the American Association for Aerosol Research
population branch statistics estimate branch lengths focal populations respect two outgroups used alternative f st based genomewide scans identifying loci associated local selective sweeps addition original population branch statistic pbs subsequently proposed branch rescalings normalized population branch statistic pbsn1 adjusts focal branch length respect outgroup branch lengths locus population branch excess pbe also incorporates median branch lengths loci pbsn1 pbe proposed less sensitive allele frequency divergence generated background selection geographically ubiquitous positive selection rather local selective sweeps however accuracy statistical power branch statistics systematically assessed simulate genomes representative large small populations varying proportions sites evolving genetic drift background selection approximated using variable ne local selective sweeps geographically parallel selective sweeps assess probability local selective sweep loci correctly identified outliers f st branch statistics find branch statistics consistently outperform f st identifying local sweeps background selection andor parallel sweeps introduced pbsn1 especially pbe correctly identify local sweeps among top outliers higher frequency pbs results validate greater specificity rescaled branch statistics pbe detect populationspecific positive selection supporting use genomic studies focused local adaptation population branch statistics widely used genomewide scans identify loci associated local adaptation study finds branch statistics accurate fst identifying local selective sweeps wide range demographic parameters models evolution also demonstrates certain branch statistics improved ability distinguish local adaptation models natural selection