Primrose Letcher, Christopher J Greenwood, Jacqui A Macdonald, Joanne Ryan, Meredith O'Connor, Kimberly C Thomson, Ebony J Biden, Felicity Painter, Catherine M Olsson, Ben Edwards, Jennifer McIntosh, Elizabeth A Spry, Delyse Hutchinson, Joyce Cleary, Tim Slade, Craig A Olsson
Life course predictors of child emotional distress during the COVID-19 pandemic: Findings from a prospective intergenerational cohort study
Journal of child psychology and psychiatry, and allied disciplines
metabolic syndrome mets characterized elevated blood pressure high blood glucose excess abdominal fat abnormal cholesterol triglyceride levels significantly increases risk various noncommunicable diseases study focuses understanding sexspecific association apolipoprotein e apoe polymorphism mets among middleaged older adults rural southern india crosssectional study utilized data centre brain researchsrinivaspura aging neuro senescence cognition cbrsanscog study participants n 3741 underwent comprehensive clinical assessments blood investigations including apoe genotyping mets defined using national cholesterol education program adult treatment panel iii ncep atp iii consensus criteria statistical analyses including chisquare tests ancova logistic regression conducted explore association apoe genotype mets components stratified sex females carrying apoe e4 allele 131fold increased odds mets 95 ci 102169 p 0035 according ncep atp iii criteria consensus criteria applied study also noted sexspecific differences association apoe various mets components including lipid levels waist circumference findings reveal sexspecific association apoe e4 allele mets females increased risk study contributes understanding genetic underpinnings mets highlights importance considering sexspecific differences mets research prevention strategies study underscores complexity mets etiology emphasizes need research elucidate role genetic environmental lifestyle factors progression particularly sexspecific contexts