Ashefet Agete, Girma Altaye, Ebrahim Talebi
Survival Analysis of Risk Factors for Mortality of Patients with Cardiovascular Diseases at Tikur Anbessa Specialized Tertiary Referral Hospital, Ethiopia: A Retrospective
Medical journal of the Islamic Republic of Iran
incidence nonsuicidal selfinjury nssi rise recent years studies shown people nssi difficulties emotion regulation cognitive control addition studies investigated cognitive emotion regulation people nssi found difficulties cognitive emotion regulation lack research cognitive emotion regulation strategies related neural mechanisms study included 117 people nssi age 1947 513 male 17 84 nonnssi participants age 1986 414 male 16 people nssi met dsm5 diagnostic criteria nonnssi participants mental physical disorders study collected participants data cognitive emotion regulation questionnaire cerq functional magnetic resonance imaging fmri explore differences psychological performance brain two groups afterwards machine learning used select found differential brain regions obtain highest correlation regions nssi allens human brain atlas database used compare information abnormal brain regions people nssi find genetic information related nssi addition gene enrichment analysis carried find related pathways specific cells may differences differences nssi participants nonnssi participants follows positive refocusing 474 p 001 refocusing plans 411 p 001 positive reappraisal 922 p 001 selfblame 630 p 001 rumination 364 p 001 catastrophizing 910 p 001 blaming others 252 p 001 precentral gyrus 604 pfdr 005 rolandic operculum 457 pfdr 005 rolandic operculum activity negatively correlated blaming others r 020 p 005 epigenetic results showed excitatory neurons p 001 inhibitory neurons p 001 significant differences two pathways transsynaptic signaling p log108 modulation chemical synaptic transmission p log108 cells people nssi inclined adopt nonadaptive cognitive emotion regulation strategies rolandic operculum also abnormally active abnormal changes rolandic operculum associated nonadaptive cognitive emotion regulation strategies changes excitatory inhibitory neurons provide hints explore abnormalities neurological mechanisms cellular level trial registration number nct04094623