Ali Saad R Alsubaie
Consumption and correlates of sweet foods, carbonated beverages, and energy drinks among primary school children in Saudi Arabia
Saudi medical journal
secondary use routine medical data key largescale clinical health services research maximum care hospital volume data generated exceeds limits big data daily basis socalled real world data essential complement knowledge results clinical trials furthermore big data may help establishing precision medicine however manual data extraction annotation workflows transfer routine data research data would complex inefficient generally best practices managing research data focus data output rather entire data journey primary sources analysis eventually make routinely collected data usable available research many hurdles overcome work present implementation automated framework timely processing clinical care data including free texts genetic data nonstructured data centralized storage findable accessible interoperable reusable fair research data maximum care university hospital identify data processing workflows necessary operate medical research data service unit maximum care hospital decompose structurally equal tasks elementary subprocesses propose framework general data processing base processes opensource softwarecomponents necessary custombuilt generic tools demonstrate application proposed framework practice describing use medical data integration center medic microservicesbased fully opensource data processing automation framework incorporates complete recording data management manipulation activities prototype implementation also includes metadata schema data provenance process validation concept requirements medic orchestrated within proposed framework data input many heterogeneous sources pseudonymization harmonization integration data warehouse finally possibilities extraction aggregation data research purposes according data protection requirements though framework panacea bringing routinebased research data compliance fair principles provides muchneeded possibility process data fully automated traceable reproducible manner