Nicola Brunswick|Eamon McCrory|Cathy J. Price|CD Frith|Uta Frith
Explicit and implicit processing of words and pseudowords by adult developmental dyslexics
Wellcome Trust|University College London|National Hospital for Neurology and Neurosurgery|Institute of Cognitive Neuroscience and Psychology|Wellcome Trust|Wellcome Trust|University College London|National Hospital for Neurology and Neurosurgery|Institute of Cognitive Neuroscience and Psychology
two groups male university students diagnosed dyslexic younger two groups control subjects similar age iq dyslexics scanned whilst reading aloud task reading implicit dyslexics performed less well peers range literacy tasks strikingly impaired phonological tasks reading aloud experiment simple words pseudowords presented slow pace reading accuracy equal dyslexics controls relative rest normal dyslexic groups activated peri extrasylvian regions left hemisphere known involved reading however dyslexic readers showed less activation controls left posterior inferior temporal cortex brodmann area ba 37 wernickes wortschatz left cerebellum left thalamus medial extrastriate cortex implicit reading experiment word pseudoword processing contrasted visually matched false fonts subjects performed feature detection paradigm dyslexic readers showed reduced activation ba 37 relative normals suggesting group difference seen experiments resides highly automated aspects reading process since ba 37 implicated previously modalityindependent naming reduced activation may indicate specific impairment lexical retrieval interestingly reading aloud experiment increased activation dyslexics relative controls premotor region brocas area ba 644 attribute result enforced use effortful compensatory strategy involving sublexical assembly articulatory routines results confirm previous findings dyslexic readers process written stimuli atypically based abnormal functioning left hemisphere reading system specifically localize deficit neural system underlying lexical retrieval