Irad Scharff|Anita Asvadurian|T. A. Treves|S. Klimovitzky|Roi Regev|Mel Rosenberg|Limor Gertner?Saad|Ophir Keret|Israel Steiner|Irit Heruti|Irit Shapira?Lichter|Amir Glik
[P1–308]: PROSPECTIVE MEMORY IMPAIRMENT IN MCI AND EARLY DEMENTIA
Rabin Medical Center|Rabin Medical Center|Tel Aviv University|Sheba Medical Center|University of Haifa|Hebrew University of Jerusalem|Rabin Medical Center|Rabin Medical Center|Rabin Medical Center|Tel Aviv University|Rabin Medical Center|Academic College of Tel Aviv-Yafo|Rabin Medical Center|Rabin Medical Center
prospective memory pm refers remembering perform intended action future examples pm failures include forgetting take medication forgetting turn oven etc pm deficits common alzheimers disease ad even mildest forms selfadministered gerocognitive examination sage convenient method assessing early dementia opposed screening tools moca mmse sage uses prospective memory task memory evaluation aim examine whether prospective memory abilities correlated cognitive performance mci mild dementia subjects spouse referred cognitive neurology clinic aged 59 intact vision hebrew literacy evaluated neurocognitive evaluation included neurologic examination mmse moca sage sage scoring performed experienced neuropsychologist blinded diagnosis cognitive evaluation statistical analysis performed using test linear regression models 33 subjects evaluated 18 females 1 subject excluded mean years education 141 22 score ranges 922 2129 2730 sage moca mmse respectively subjects divided intact impaired pm according performance sage pm task moca scores significantly lower impaired pm group n14 mean2314 vs intact group n18 mean2617 p00009 also difference moca episodic memory scores groups however difference less pronounced expected total sage scores linearly correlated moca scores r20362 p00003 mmse scores r20256 p0004 pm impairment usually underdiagnosed moreover pm abilities predicts selfreported medication adherence older adults one earliest signs ad sage could suitable screening tool pm impairment cognitive evaluation especially cognitive deficits scarce