Angela R Starkweather, Wanli Xu, Katherine E Gnall, Mariel Emrich, Camille L Garnsey, Zachary E Magin, Weizi Wu, Joseph Fetta, Erik J Groessl, Crystal Park
Testing Biological and Psychological Pathways of Emotion Regulation as a Primary Mechanism of Action in Yoga Interventions for Chronic Low Back Pain: Protocol for a Randomized Controlled Trial
JMIR research protocols
multiomics experiments bulk singlecell resolution facilitate discovery hypothesisgenerating biomarkers predicting response therapy well aid uncovering mechanistic insights cellular microenvironmental processes many methods data integration developed identification key elements explain predict disease risk biological outcomes heterogeneous graph representation multiomics data provides advantage discerning patterns suitable predictiveexploratory analysis thus permitting modeling complex relationships graphbased approachesincluding graph neural networkspotentially offer reliable methodological toolset provide tangible alternative scientists clinicians seek ideas implementation strategies integrated analysis omics sets biomedical research graphbased workflows continue push limits technological envelope perspective provides focused literature review research articles graph machine learning utilized integrated multiomics data analyses several examples demonstrate effectiveness graphbased approaches