Vesna Borovnik Lesjak, Andrej Šorgo, Matej Strnad
Development, validation and assessment of the test on knowledge about basic life support and use of automated external defibrillator among schoolchildren
Scandinavian journal of trauma, resuscitation and emergency medicine
examine association earlylife atopic manifestations later risk inflammatory bowel disease ibd prospective data scarce populationbased babies southeast sweden abis norwegian mother father child moba cohorts follow children birth abis 19971999 moba 20002009 end 2021 based validated questionnaires parents prospectively reported information asthma foodrelated allergic symptoms atopic dermatitis allergic rhinitis age 3 ibd defined 2 diagnostic records national health registries cox regression estimated hazard ratios adjusted ahrs parental ibd atopy education level smoking habits national origin cohortspecific estimates pooled using randomeffects model compiled data 83 311 children abis n 9041 moba n 74 270 1 174 756 personyears followup 301 participants diagnosed ibd children atopic dermatitis age 3 increased risk ibd pooled ahr 146 95 ci 113188 crohns disease pooled ahr 153 95ci 104226 ulcerative colitis pooled ahr 178 95ci 115275 conversely atopic manifestation age 3 associated ibd pooled ahr 120 95ci 095152 analyses specifically focused earlylife foodrelated allergic symptoms asthma allergic rhinitis atopic manifestations early childhood overall associated ibd children atopic dermatitis specifically increased risk developing ibd suggesting shared etiologic traits findings might useful identifying atrisk individuals ibd