Alethea Jerebine, Mohammadreza Mohebbi, Natalie Lander, Emma L J Eyre, Michael J Duncan, Lisa M Barnett
Playing it safe: The relationship between parent attitudes to risk and injury, and children's adventurous play and physical activity
Psychology of sport and exercise
two prominent organizations american society clinical oncology national quality forum nqf developed cancer quality metric aimed reducing systemic anticancer therapy administration end life metric nqf 0210 patients receiving chemotherapy last 14 days life critiqued focusing care decedents including broader population patients may benefit treatment evaluate whether overall population patients metastatic cancer receiving care practices higher rates oncologic therapy advanced disease experience longer survival nationwide populationbased cohort study used flatiron health deidentified electronic health record database patients diagnosed metastatic advanced disease identify adult patients aged 18 years 1 6 common cancers breast cancer colorectal cancer nonsmall cell lung cancer nsclc pancreatic cancer renal cell carcinoma urothelial cancer treated health care practices 2015 2019 practices stratified quintiles based retrospectively measured rates nqf 0210 overall survival compared disease type among patients treated practice quintile time metastatic diagnosis using multivariable cox proportional hazard models bonferroni correction multiple comparisons data analyzed july 2021 july 2023 practicelevel nqf 0210 quintiles overall survival 78 446 patients mean sd age 673 111 years 522 female across 144 practices common cancer types nsclc 34 201 patients 436 colorectal cancer 15 804 patients 201 practicelevel nqf 0210 rates varied 109 quintile 1 323 quintile 5 nsclc 68 quintile 1 284 quintile 5 colorectal cancer statistically significant differences survival observed patients treated highest lowest nqf 0210 quintiles compared patients seen practices lowest nqf 0210 quintiles hazard ratio death among patients seen highest quintiles varied 074 95 ci 055099 renal cell carcinoma 141 95 ci 098202 urothelial cancer differences statistically significant applying bonferroniadjusted critical p 008 cohort study patients metastatic advanced cancer treated practices higher nqf 0210 rates improved survival future efforts focus helping oncologists identify additional therapy futile developing goals care communication skills aligning payment incentives improved endoflife care