Hakimeh Vahedparast, Mahasty Ganjoo, Farkhondeh Ghasemi, Leila Dehghani
Information-seeking process and clinical scenario solving: introduction of a new tool in nursing education
BMC medical education
cachexia wasting syndrome afflicts endstage cancer patients whereas consensus statement definition cachexia recently accomplished useful measurement condition present lacking aim present review discuss advantage introducing measurement tumor burden better overall evaluation cachexia suggestion ensues somewhat novel perspective field infectious disease research careful measurement pathogen load ie different host genotypes leads definition concept tolerance infectious insult indeed tolerance concurs together classical resistance maintaining host reproductive fitness health state noticeably similar reasoning may apply tumor biology well whereas extent cachexia increases tumor burden relationship two correlates tumor progression fluctuates broad range selected literature studies rodent model significant variation course wasting illness cancer observed quantitatively assessed comparing experimental groups marked different genotype drug treatment diet gender studies may classified two categories former experimental condition associated milder cachexia accompanied lesser tumor burden latter inhibition cachexia results disentangled tumor burden whole number cancer cells results unchanged even paradoxically increased addition survey even context human malignancy significance feasibility plotting quantitative estimates cachexia whole tumor burden ultimately principal endeavor introducing measurement tumor burden experimental clinical oncology may achieve better assessment interindividual variation host vulnerability cancer cachexia