Samuel Allemann|Robby Nieuwlaat|Bart J F van den Bemt|Kurt E. Hersberger|Isabelle Arnet
Matching Adherence Interventions to Patient Determinants Using the Theoretical Domains Framework
University of Basel|McMaster University|Sint Maartenskliniek|Radboud University Nijmegen|Radboud University Medical Center|University of Basel|University of Basel
introduction despite much research interventions improve medication adherence report disappointing inconsistent results tailored approaches match interventions patient determinants nonadherence seldom used clinical trials presence multitude theoretical frameworks models categorize interventions patient determinants complicated development common categories shared interventions determinants retrieved potential interventions patient determinants published literature medication adherence matched like locks keys categorized according theoretical domains framework tdf methods identified relevant literature reviews interventions determinants pragmatic literature search extracted interventions determinants grouped similar concepts umbrella terms assigned tdf categories steps finalized consensus discussion authors results sixteen articles 5 determinants 11 interventions included analysis extracted 103 interventions 42 determinants divided 26 modifiable 16 unmodifiable determinants interventions modifiable determinants matched within 11 categories knowledge skills socialprofessional role identity beliefs capabilities beliefs consequences intentions memory attention decision processes environmental context resources social influences emotion behavioral regulation conclusion published trials medication adherence congruence interventions determinants assessed matching interventions determinants successful interventions medication adherence target current modifiable determinants tailored unmodifiable determinants modifiable unmodifiable determinants need assessed inclusion intervention studies identify patients need adherence intervention matched categories may useful develop interventions trials investigate effectiveness adherence interventions