Jacqueline Y Ding, Stacey L Cleary, Prue E Morgan
Health literacy in adolescents and young adults with cerebral palsy: a mixed methods systematic review
Disability and rehabilitation
complex actions regarded concatenation simple motor acts arranged according specific rules caudal part brocas region left brodmanns area 44 ba 44 involved processing hierarchically organized behaviors aimed test hypothesis area may also play role learning structured motor sequences address issue investigated inhibitory effects continuous thetaburst tms ctbs applied left ba 44 healthy subjects performed serial rt task srtt srtt widely used study motor skill learning also interest complex structured sequences subjects spontaneously organize smaller subsequences referred chunks control ctbs applied vertex another group underwent experiment control subjects showed general practice learning effect evidenced progressive decrease rt across blocks sequencespecific learning effect demonstrated significant rt increase pseudorandom sequence contrast ctbs applied left ba 44 subjects lacked general practice sequencespecific learning effects however surprisingly chunking pattern preserved remained indistinguishable controls present study indicates left ba 44 plays role motor sequence learning without involved elementary chunking dissociation chunking sequence learning could explained postulate left ba 44 intervenes high hierarchical level processing possibly integrate elementary chunks together