Ashish Kumar Singh|Saurav Das|Surinder Singh|Varsha Rani Gajamer|Nilu Pradhan|Yangchen D. Lepcha|Hare Krishna Tiwari
Prevalence of antibiotic resistance in commensal Escherichia coli among the children in rural hill communities of Northeast India
Sikkim University|Sikkim University|Panjab University|Sikkim University|Sikkim University|Government of Sikkim|Sikkim University
commensal bacteria representative reservoir antibiotic resistance genes present community usage antibiotics along demographic factors generally associated increase antibiotics resistance pathogens northeast ne india untapped regard antibiotic resistance prevalence spread current study prevalence antibioticresistant commensal escherichia coli preschool schoolgoing children n 550 114 years old rural areas state sikkiman ne indian state respect associated demographic factors investigated total 550 fecal e coli isolates collected july 2015 june 2017 structured questionnaire used collect data ascertain potential factors associated carriage antibiotic resistance e coli among children statistical analysis along logistic regression identified potential external factors affecting observed antibiotic resistance pattern data indicated high prevalence resistance common antibiotics like ampicillin 92 ceftazidime 90 cefoxitin 88 streptomycin 40 tetracycline 36 resistance chloramphenicol resistance combination penicillin quinolone group antibiotics observed fiftytwo percent isolates positive correlation harboring antibiotics resistant e coli different demographic factors observed children living nuclear family vs joint family 6315 018 95 ci011028 p 001 higher secondary maternal education vs college graduates 5927 075 95 ci055102 p 002 close association different demographic factors high prevalence antibioticresistant commensal e coli current study suggests concern rising misuse antibiotics warrants future threat emergence multidrugresistant pathogen isolates