René Westerhausen|Eileen Lüders|Karsten Specht|Sonja H. Ofte|A.W. Toga|Paul Thompson|Turid Helland|Kenneth Hugdahl
Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years
University of Bergen|University of California, Los Angeles|Haukeland University Hospital|University of Bergen|University of California, Los Angeles|University of California, Los Angeles|University of Bergen|University of Bergen|Haukeland University Hospital
establishment efficient exchange information cerebral hemispheres crucial importance developing functionally lateralized brain corpus callosum major connection cerebral hemispheres grows constantly throughout childhood adolescence however behavioral studies suggest existence critical time period callosal functional development starting around age 6 years present longitudinal study examining cohort 20 children age 6 8 years assessed relationship structural functional callosal development time period structural development quantified calculating increase callosal thickness using shapebased computational analysis midsagittal corpus callosum obtained magnetic resonance imaging functional development assessed speech discrimination task based dichotic presentation consonantvowel syllables statistical analysis revealed children whose callosal isthmus increased thickness course 2 years showed decrease interhemispheric information transfer however children exhibiting decrease isthmus thickness revealed increase information transfer results might indicate refinement process callosal connections optimize neuronal communication developing cerebral hemispheres