André Reynaldo Santos Perissé|Reinaldo Souza?Santos|Rosemere Duarte|Fernanda Nunes Santos|Célia Regina de Andrade|Nádia Cristina Pinheiro Rodrigues|Joyce Mendes de Andrade Schramm|Edimilson Domingues da Silva|Ludmilla da Silva Viana Jacobson|Maria Cristina Ferreira Lemos|Andréa Sobral
Zika, dengue and chikungunya population prevalence in Rio de Janeiro city, Brazil, and the importance of seroprevalence studies to estimate the real number of infected individuals
Escola Nacional de Saúde Pública|Fundação Oswaldo Cruz|Escola Nacional de Saúde Pública|Fundação Oswaldo Cruz|Escola Nacional de Saúde Pública|Fundação Oswaldo Cruz|Escola Nacional de Saúde Pública|Fundação Oswaldo Cruz|Escola Nacional de Saúde Pública|Departamento de Epidemiología|Fundação Oswaldo Cruz|Escola Nacional de Saúde Pública|Fundação Oswaldo Cruz|Escola Nacional de Saúde Pública|Departamento de Epidemiología|Fundação Oswaldo Cruz|Fundação Oswaldo Cruz|Universidade Federal Fluminense|Secretaria Municipal de Saúde|Escola Nacional de Saúde Pública|Fundação Oswaldo Cruz
last 40 years latin america countries including brazil suffered emergence reemergence arboviruses first dengue denv recently zika zikv chikungunya chikv three arboviruses currently endemic brazil caused major outbreaks recent years rio de janeiro city host last summer olympic games football world cup specially affected surveillance system based symptomatic reports place rio true number affected individuals unknown due great number zika dengue chikungunya asymptomatic cases seroprevalence studies suitable evaluate real number cases given population performed populational seroprevalence survey rio recruitment sample volunteers ages gender july october 2018 within randomly selected census tracts household total 2120 volunteers interviewed tested rapid immunochromatographic test zikv denv chikv individuals positive results igg andor igm one virus classified accordingly test results positive zikv denv classified flaviviruses corrected sample design nonresponse data analysis calculated point estimate prevalence 95 confidence intervals virus arbovirus prevalence rios population n 6688927 estimated 486 95 ci 448524 n 3254121 flaviviruses 180 95 ci 148212 n 1204765 chikv approximately 170 95 ci 141201 n 1145674 rios population contact three arboviruses reported cases zika dengue chikungunya current surveillance system place insufficient estimate real numbers data indicate zika seroprevalence could least five times chikungunya 45 times bigger high number individuals never infected three arboviruses may indicate proper scenario future outbreaks