Konstadina Griva|Andrew Davenport|Michael J. Harrison|Stanton Newman
Non-adherence to Immunosuppressive Medications in Kidney Transplantation: Intent Vs. Forgetfulness and Clinical Markers of Medication Intake
National University of Singapore|City, University of London|The Royal Free Hospital|University College London|University College London|City, University of London
although adherence immunosupressive medication transplantation important maximize good clinical outcomes remains suboptimal wellunderstood purpose study examine intentional unintentional nonadherence immunosuppression medication kidney transplant patientsa crosssectional sample n218 patients 496 123 years recruited london uk 19992002 completed measures medication beliefs qualityoflife depression transplantationspecific emotions adherence measured selfreport serial immunosuppressive assaysintentional nonadherence low 138 yet 624 admitted unintentional nonadherence 254 subtarget immunosuppressive levels risk subtarget serum immunosuppressive levels greater patients admitting unintentional nonadherence or84 p0004 dialysis vintage doubts necessity lower worry viability graft explained r2161 36 selfreport nonadherence depression related intentional nonadherencenonadherence common kidney transplantation efforts increase adherence implemented targeting necessity beliefs monitoring depression promoting strategies decrease forgetfulness