Sing Yu Moorcraft|Cheryl Marriott|Clare Peckitt|David Cunningham|Ian Chau|Naureen Starling|David Watkins|Sheela Rao
Patients’ willingness to participate in clinical trials and their views on aspects of cancer research: results of a prospective patient survey
Royal Marsden NHS Foundation Trust|Royal Marsden NHS Foundation Trust|Royal Marsden NHS Foundation Trust|Royal Marsden NHS Foundation Trust|Royal Marsden NHS Foundation Trust|Royal Marsden NHS Foundation Trust|Royal Marsden NHS Foundation Trust|Royal Marsden NHS Foundation Trust
recruitment clinical trials challenging slower anticipated prospective patient survey aimed investigate proportion patients approached trial agree participate motivations trial participation views aspects cancer researchpatients approached participation clinical trials gastrointestinal lymphoma unit royal marsden invited complete questionnaire statistical analysis mainly descriptive percentages reported univariate logistic regression analysis used determine associations patient characteristics patient responsesfrom august 2013july 2014 276 patients received 298 clinical trial patient information sheets asked complete questionnaire majority patients 263 patients 88 consented clinical trial 249 263 patients 95 completed questionnaire multiple factors influenced decisions participate clinical trials patients stating important reasons trial offered best treatment available trial results could benefit others 249 questionnaire respondents 78 would donate tissue genetic research 75 would consider participating studies requiring research biopsy 75 felt patients informed trial results patients treated palliative intent received multiple lines treatment willing consider research biopsies patients approached clinical trial investigational medicinal product 4850 would liked information study drugsproceduresthe majority patients approached clinical trial consented one trials patients motivations trial participation included potential personal benefit altruistic reasons high proportion patients willing donate tissue research consider trials involving repeat biopsies majority patients feel participants informed trial results group patients would like detailed trial information