Deborah J Watson, Loïca Ducheine
The Role of the Nurse in the Prehabilitation Unit
Seminars in oncology nursing
study aims examine causal relationship dietary factors ulcerative colitis uc analysis utilized data genomewide association studies gwas dried fruit vegetables processed meat fresh fruit cereal intake examined exposure factors uc considered outcome twosample mendelian randomization tsmr analysis performed using methods heterogeneity horizontal pleiotropy assessments conducted ensure robustness findings additionally applied false discovery rate fdr corrections multiple tests analysis revealed significant inverse causal relationship dried fruit intake uc risk odds ratio 0488 95 confidence interval ci 0261 0915 p 0025 significant association observed vegetable intake 1742 95 ci 0561 5415 p 0337 processed meat intake 1136 95 ci 0552 2339 p 0729 fresh fruit intake 0977 95 ci 0465 2054 p 0952 cereal intake 1195 95 ci 0669 2134 p 0547 low heterogeneity observed across analyses confirmation stability leaveoneout analysis reinforce reliability results moreover adjusting multiple tests none dietary factors reached pvalue conventional significance threshold 005 study provides evidence potential association dried fruit intake reduced risk uc mr studies incorporating larger gwas datasets needed confirm findings