Eider M. Arenaza?Urquijo|Brigitte Landeau|Renaud La Joie|Katell Mevel|Florence Mézenge|Audrey Perrotin|Béatrice Desgranges|David Bartrés?Faz|Francis Eustache|Gaël Chételat
Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders
Universitat de Barcelona|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen|Universitat de Barcelona|Consorci Institut D'Investigacions Biomediques August Pi I Sunyer|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen|Inserm|Université de Caen Normandie|École Pratique des Hautes Études|Centre Hospitalier Universitaire de Caen
educated elders less susceptible agerelated pathological cognitive changes aimed providing comprehensive contribution neural mechanism underlying effect thanks multimodal approach thirtysix healthy elders selected based neuropsychological assessments cerebral amyloid imaging ie presenting normal cognition negative florbetapirpet scan subjects underwent structural mri fdgpet restingstate functional mri scans assessed relationships years education gray matter volume ii gray matter metabolism iii functional connectivity brain areas showing associations volume metabolism higher years education related greater volume superior temporal gyrus insula anterior cingulate cortex greater metabolism anterior cingulate cortex latter thus showed volume metabolism increases education seed connectivity analyses based region showed education positively related functional connectivity anterior cingulate cortex hippocampus well inferior frontal lobe posterior cingulate cortex angular gyrus increased connectivity turn related improved cognitive performances reinforcement connectivity anterior cingulate cortex distant cortical areas frontal temporal parietal lobes appears one mechanisms underlying educationrelated reserve healthy elders