Nandagudi Srinivasa Murthy|Ashok Sehgal|L Satyanarayana|Das Dk|Vikram Singh|B. C. Das|Mohit Gupta|Mitra Ab|Luthra Uk
Risk factors related to biological behaviour of precancerous lesions of the uterine cervix
Maulana Azad Medical College|Institute of Cytology and Preventive Oncology
study factors related cervical carcinogenesis cohort 1107 cervical dysplasia along 1077 controls matched age parity followed prospectively follow 75 dysplasia cases progressed carcinoma situ overall rate progression dysplasia malignancy observed 157 end 108 months followup analysis progression rates relation various factors revealed significantly higher progression rates initially higher grade dysplastic lesions early age consummation marriage acm factors religion literacy status patient number pregnancies presence cervical erosion history fetal loss positivity hsvii antibodies reveal statistical significance casecontrol comparison detection hpv 1618 situ hybridisation revealed presence hpv 1618 sequences 673 dysplasia subjects progressed carcinoma situ 273 precancerous cases regressed normalcy difference found statistically significant p less 0001