Danielle Hollar, Sarah E Messiah, Gabriela Lopez-Mitnik, T Lucas Hollar, Marie Almon, Arthur S Agatston
Effect of a two-year obesity prevention intervention on percentile changes in body mass index and academic performance in low-income elementary school children
American journal of public health
study aimed identify factors affect lymphovascular space invasion lvsi endometrial cancer ec using machine learning technology build clinical risk assessment model based factors samples collected may 2017 march 2022 including 312 ec patients received treatment xuzhou medical university affiliated hospital lianyungang 219 cases collected training group 93 validation group clinical data laboratory indicators analyzed logistic regression least absolute shrinkage selection operator lasso regression used analyze risk factors construct risk models lvsi nonlvsi groups showed statistical significance clinical data laboratory indicators p 005 multivariable logistic regression analysis identified independent risk factors lvsi ec myometrial infiltration depth cervical stromal invasion lymphocyte count lym monocyte count mono albumin alb fibrinogen fib p 005 lasso regression identified 19 key feature factors model construction training validation groups risk scores logistic lasso models significantly higher lvsi group compared nonlvsi group p 0001 model built based machine learning effectively predict lvsi ec enhance preoperative decisionmaking reliability model demonstrated significant difference risk scores lvsi nonlvsi patients training validation groups