Kristine Yaffe|Cherie Falvey|Tamara B. Harris|Anne B. Newman|Suzanne Satterfield|Annemarie Koster|Hilsa N. Ayonayon|Eleanor M. Simonsick|Allison R. Kaup
O2-13-03: Do socioeconomic disparities explain higher dementia incidence among black older adults?
University of California, San Francisco|University of California, San Francisco|National Institutes of Health|University of Pittsburgh|University of Tennessee Health Science Center|National Institute on Aging|University of California, San Francisco|National Institute on Aging|University of California, San Francisco
dementia rates united states shown higher among black white elders whether increased incidence reflects greater risk factors among black white elders extensively evaluated sought determine blackwhite differences dementia rates existed among cohort community dwelling elders whether differences observed could explained socioeconomic status ses indicators income financial adequacy education literacy healthrelated factors evaluated dementia risk among 3075 black white elders mean age 741 years 417 black 515 female participating prospective health aging body composition study free dementia baseline dementia determined 12 year followup prescribed dementia medications hospital records decline global cognition examine influence ses health related factors dementia rates conducted series coxproportional hazard models variables sequentially added base model covariate blocks followup 575 187 participants developed dementia black participants greater risk developing dementia white participants 219 vs 164 p0001 unadjusted hazard ratio hr 157 95 confidence interval ci 133 184 hr lessened somewhat adjustment demographics apoe e4 comorbidities lifestyle factors 140 95 ci 117 168 greatly reduced longer statistically significant ses added model hr 117 95 ci 095145 additional adjustment baseline 3ms score attenuated effect size slightly results suggest differences risk factors especially ses may contribute higher dementia rates observed among black compared white elders strategies aimed reducing disparities may favorably impact dementia incidence