Hanna van Waart|Wim H. van Harten|Laurien M. Buffart|Gabe S. Sonke|Martijn M. Stuiver|Neil K. Aaronson
Why do patients choose (not) to participate in an exercise trial during adjuvant chemotherapy for breast cancer?
The Netherlands Cancer Institute|The Netherlands Cancer Institute|EMGO Institute for Health and Care Research|The Netherlands Cancer Institute|The Netherlands Cancer Institute|The Netherlands Cancer Institute
abstract objective 25 50 patients invited participate clinical trialbased physical exercise programs cancer treatment agree purpose study identify factors associated significantly decision participate randomized controlled trial physical exercise adjuvant chemotherapy breast cancer methods based questionnaire data compared trial participants nonparticipants range sociodemographic clinical healthrelated practical behavioral attitudinal variables results two hundred thirty 524 patients agreed participate trial 44 294 56 nonparticipants indicated wanted exercise wish exercise context trial preferred exercise relatively similar trial participants likely maintenance exercise stage nonparticipants wish exercise significantly lower level education less likely working reported fatigue lower healthrelated quality life lower sense selfefficacy negative attitudes towards exercise less social support perceived fewer benefits barriers exercising treatment trial participants conclusion minimizing practical barriers participation providing educational materials potential benefits exercise giving adequate professional social network encouragement may increase number patients willing exercise treatment participate studies copyright 2015 john wiley amp sons ltd