Elizabeth Murray|Michael Sweeting|Charlotte Dack|Kingshuk Pal|Kerstin Modrow|Mohammed T Hudda|Jinshuo Li|Jamie Ross|Ghadah Alkhaldi|Maria Barnard|Andrew Farmer|Susan Michie|Lucy Yardley|Carl May|Steve Parrott|Fiona Stevenson|Malcolm Knox|David Patterson
Web-based self-management support for people with type 2 diabetes (HeLP-Diabetes): randomised controlled trial in English primary care
University College London|Primary Health Care|University of Cambridge|University of Bath|University College London|Primary Health Care|University College London|Primary Health Care|Population Health Research Institute|St George's, University of London|University of York|Primary Health Care|University College London|Primary Health Care|University College London|Whittington Health NHS Trust|University of Oxford|Nuffield Health|University College London|University of Southampton|University of Oxford|Nuffield Health|University of Southampton|Faculty of Public Health|University of York|University College London|Primary Health Care|University College London|Primary Health Care|Whittington Health NHS Trust
determine effectiveness webbased selfmanagement programme people type 2 diabetes improving glycaemic control reducing diabetesrelated distressindividually randomised twoarm controlled trial21 general practices englandadults aged 18 diagnosis type 2 diabetes registered participating general practicesusual care plus either healthy living people diabetes helpdiabetes interactive theoretically informed webbased selfmanagement programme simple textbased website containing basic information onlyjoint primary outcomes glycated haemoglobin hba1c diabetesrelated distress measured problem areas diabetes paid scale collected 3 12 months randomisation 12 months primary outcome point research nurses blind allocation collected clinical data participants completed selfreport questionnaires onlinethe analysis compared groups randomised intention treat using linear mixed effects model adjusted baseline data multiple imputation missing valuesof 374 participants randomised september 2013 december 2014 185 allocated intervention 189 control final 12 month followup data hba1c available 318 85 paid 337 90 participants 291 78 321 86 responses recorded within predefined window 1014 months participants intervention group lower hba1c control mean difference 024 95 ci 044 0049 p0014 significant overall difference groups mean paid score p021 prespecified subgroup analysis participants recently diagnosed diabetes showed beneficial impact intervention group p 0004 reported harmsaccess helpdiabetes improved glycaemic control 12 monthsisrctn02123133