Cynthia C Harper, Lavanya Rao, Isabel Muñoz, Lisa Stern, Jennifer L Kerns, Miriam Parra, Brittany D Chambers, Corinne H Rocca
Agency in Contraceptive Decision-Making in Patient Care: a Psychometric Measure
Journal of general internal medicine
adjuvant treatments valuable decrease recurrence rate improve survival earlystage cervical cancer patients escc therefore recurrence risk evaluation critical choice postoperative treatment magnetic resonance imaging mri based radiomics nomogram integrating postoperative adjuvant treatments constructed validated externally improve recurrence risk prediction escc 212 escc patients underwent surgery adjuvant treatments three centers enrolled divided training internal validation external validation cohorts clinical data pretreatment t2weighted images t2wi retrieved analyzed radiomics models constructed using machine learning methods features extracted screen sagittal axial t2wi nomogram recurrence prediction build evaluated using multivariable logistic regression analysis integrating radiomic signature adjuvant treatments total 8 radiomic features screened 1020 extracted features extreme gradient boosting xgboost model based mri radiomic features performed best recurrence prediction area curve auc 0833 0822 internal external validation cohorts respectively nomogram integrating radiomic signature clinical factors achieved auc 0806 0718 internal external validation cohorts respectively recurrence risk prediction escc study nomogram integrating t2wi radiomic signature clinical factors valuable predict recurrence risk thereby allowing timely planning effective treatments escc high risk recurrence