Angelina A Joho, Mwajuma B Mdoe, Theresia J Masoi, James J Yahaya
Perceived barriers and factors influencing uptake of breast cancer screening among women: a population-based cross-sectional study
Scientific reports
coronavirus disease 2019 covid19related disruptions healthcare services clinical outcomes predicted documented however little known antiretroviral therapy art adherence disruptions caused covid19 pandemic manifested amidst undetectable untransmittable campaign initiative using patients viral load proxy medication adherence study aimed determine adherence art firstline medications among adult people living human immunodeficiency virus plwhiv university teaching hospital lusaka zambia pandemic hospitalbased crosssectional study secondary data plwhiv registered receive art adult infectious disease centre extracted smartcare electronic health record system constitute resultant data set study used data extraction form used extract values dependent art adherence measured viral load detectability independent variables imported statistical analysis tool stata version 161 mp descriptive statistics individual characteristics testing associations using pearsons chisquare test stratified combined multivariable logistic regression performed 7281 adult plwhiv included study 90 95 ci 8396 virally detectable estimates odds ratios detectable viral load remained significantly higher among adult plwhiv initiated art uu campaign launched zambia monthly 251 131903 6monthly 475 352641 dispensing dolutegravirbased regimen 6monthly dispensing efavirenzbased regimen 467 2161008 compared counterparts overall estimates showed us picture 414 322531 adjusted predictor variables found high proportion people detectable viral load study population irrespective medication refill interval type regimen concentrated among adult plwhiv started treatment covid19 epidemic waves compared started treatment pandemic observed disparity suggests inherent impact pandemic adherence art among adult plwhiv lusaka zambia illustrates exposed program responses external shocks especially already weakened health systems need create program response buffers resilient programspecific strategies minimize effect external disruptions