Fanny Laliève, Stéphane Decramer, Laurence Heidet, Véronique Baudouin, Annie Lahoche, Brigitte Llanas, Pierre Cochat, Julie Tenenbaum, Marie-Pierre Lavocat, Philippe Eckart, Françoise Broux, Gwenaelle Roussey, Sylvie Cloarec, Isabelle Vrillon, Olivier Dunand, Lucie Bessenay, Michel Tsimaratos, François Nobili, Christine Pietrement, Loïc De Parscau, Valérie Bonneville, Nicolas Rodier, Cécile Saint-Martin, Nicolas Chassaing, Laurence Michel-Calemard, Vincent Moriniere, Christine Bellanné-Chantelot, Claire Bahans, Vincent Guigonis
School level of children carrying a HNF1B variant or a deletion
European journal of human genetics : EJHG
rhabdomyolysis children highly variable condition presentations ranging myalgias severe complications like acute renal failure sought explore demographics incidence pediatric rhabdomyolysis hospitalizations rates associated renal failure current understanding limited retrospective analysis using healthcare cost utilization project kids inpatient database identify children hospitalized primary diagnosis rhabdomyolysis data analyzed demographic characteristics well geographic temporal trends multivariable logistic regression used identify characteristics associated rhabdomyolysisassociated acute renal failure 2006 2016 8599 hospitalized children primary diagnosis rhabdomyolysis overall hospitalizations pediatric rhabdomyolysis increasing time geographic peaks south northeast regions seasonal peaks march august though renal morbidity diagnosed 85 children requiring hospitalization rhabdomyolysis patients required renal replacement therapy 041 death rare 003 characteristics associated renal failure included male sex age greater 15 years nonhispanic black race though renal failure occurs significant rate children hospitalized rhabdomyolysis severe complications including death rare number children hospitalized rhabdomyolysis varies geographic region month year future studies needed explore etiologies rhabdomyolysis laboratory values predict higher risk morbidity mortality children rhabdomyolysis