Lindsay S. Mayberry|Chandra Y. Osborn
Empirical Validation of the Information–Motivation–Behavioral Skills Model of Diabetes Medication Adherence: A Framework for Intervention
Vanderbilt University Medical Center|Vanderbilt University Medical Center
suboptimal adherence diabetes medications prevalent associated unfavorable health outcomes remains unclear intervention content necessary effectively promote medication adherence diabetes disease contexts informationmotivationbehavioral skills imb model effectively explained promoted medication adherence thus may utility explaining promoting adherence diabetes medications tested imb models hypotheses sample adults type 2 diabetesparticipants n 314 completed intervieweradministered survey a1c test structural equation models tested effects diabetes medication adherencerelated information motivation behavioral skills medication adherence effect medication adherence a1cthe imb elements explained 41 variance adherence adherence explained 9 variance a1c predicted behavioral skills direct effect adherence 059 p 0001 mediated effects information indirect effect 008 001015 motivation indirect effect 012 005020 adherence medication adherence significantly predicted glycemic control 030 p 0001 neither insulin status regimen complexity associated adherence neither moderated associations imb constructs adherencethe results support imb models predictions identify modifiable intervenable determinants diabetes medication adherence medication adherence promotion interventions may benefit content targeting patients medication adherencerelated information motivation behavioral skills assessing degree change determinants leads changes medication adherence behavior