Geraldine O’ Rourke|Julie Jordan O’ Brien
Identifying the barriers to antiepileptic drug adherence among adults with epilepsy
Sligo University Hospital|Royal College of Surgeons in Ireland
identify barriers antiepileptic drug aed adherence among adults epilepsy awe impact aed nonadherence quality life qol also examinedsystematic design sr study search strategy undertaken time limits articles published english medline cinanl psycinfo embase cochrane databases grey literature sources eligibility criteria included participants epilepsy 18 years prescribed aeds adherence defined adherence assessment measurements identified screening process undertaken select eligible studies eight studies met inclusion criteria included quantitative synthesis quality evidence conducted using ebl critical appraisal checklist assessing risk bias within individual studiesacross included studies high prevalence nonadherence identified aed nonadherence associated specific beliefs medications depressed anxious poor medication selfadministration management uncontrolled recent seizures frequent medication dosage times poor physicianpatient relationship perceived social support additionally aed nonadherence impacted negatively qol result poor seizure controlalthough included studies good quality risk biases reduced generalisability results findings suggested comprehensive adherence assessments routinely performed recommendations future research include use longitudinal research designs follow sr include 1618yearold population