Helena C. Kraemer
Pitfalls of Multisite Randomized Clinical Trials of Efficacy and Effectiveness
Stanford University
article discusses common pitfalls multisite randomized clinical trials efficacy effectiveness issues considered include 1 premature initiation 2 ineffective study structure 3 much little communication among researchers 4 neglect site differences 5 use naked p values 6 premature closure 7 overreliance interpretation memory individual researchers future researchers aware common pitfalls may able avoid