Satish Ranka|Jennifer M. Gee|Lajos Bíró|Gary M. Brett|Shikha Saha|Paul A. Kroon|Jane Skinner|Anthony R Hart|Aedín Cassidy|Michael Rhodes|Ian T. Johnson
Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake
Norfolk and Norwich University Hospital|Norfolk and Norwich University Hospital|Quadram Institute|National Institute for Food and Nutrition Science|Quadram Institute|Norfolk and Norwich University Hospital|Norfolk and Norwich University Hospital|Quadram Institute|Quadram Institute|Norfolk and Norwich University Hospital|University of East Anglia|Norfolk and Norwich University Hospital|University of East Anglia|Norfolk and Norwich University Hospital|Norfolk and Norwich University Hospital|Quadram Institute
measure relationship quercetin naringenin intakes estimated food frequency questionnaire ffq urinary excretion quercetin naringenin aglycones enzymatic hydrolysis human volunteersvolunteers recruited via human nutrition unit volunteer databank institute food research norwich sixtythree volunteers recruited study 14 excluded 49 completed study modified ffq developed used estimate daily intake quercetin naringenin 49 healthy volunteers also provided five 24h urine samples 2week period urinary excretion quercetin naringenin metabolites determined solidphase extraction highpressure liquid chromatographythe estimated mean intakes quercetin naringenin 294 mg sd 150 581 mg sd 627 per day respectively mean urinary excretion quercetin 601 microg sd 331 naringenin 056 mg sd 04 correlation ffq estimated intake quercetin naringenin levels excreted urine r082 p00001 r025 p005 respectivelywe observed statistically significant correlation urinary excretion quercetin naringenin metabolites dietary intake estimated ffq use ffqs epidemiological studies requiring estimate flavonoid intake seems justified