Elizabeth Rose Mayeda|Andrew J. Karter|Elbert S. Huang|Howard H. Moffet|Mary N. Haan|Rachel A. Whitmer
Racial/Ethnic Differences in Dementia Risk Among Older Type 2 Diabetic Patients: The Diabetes and Aging Study
University of California, San Francisco|Kaiser Permanente|University of Chicago|Kaiser Permanente|University of California, San Francisco|Kaiser Permanente
objective although patients type 2 diabetes double risk dementia potential racialethnic differences dementia risk explored population evaluated racialethnic differences dementia potential explanatory factors among older diabetic patients research design methods identified 22171 diabetic patients without preexisting dementia aged 60 years 14546 nonhispanic whites 2484 african americans 2363 latinos 2262 asians 516 native americans kaiser permanente northern california diabetes registry abstracted prevalent medical history 1 january 1996 31 december 1997 dementia incidence 1 january 1998 31 december 2007 medical records calculated ageadjusted incidence densities fit cox proportional hazards models adjusted age sex education diabetes duration markers clinical control results dementia diagnosed 3796 171 patients ageadjusted dementia incidence densities highest among native americans 341000 personyears african americans 271000 personyears lowest among asians 191000 personyears fully adjusted model hazard ratios 95 cis relative asians 164 130206 native americans 144 124167 african americans 130 115147 nonhispanic whites 119 102140 latinos adjustment diabetesrelated complications neighborhood deprivation index change results conclusions among type 2 diabetic patients followed 10 years african americans native americans 4060 greater risk dementia compared asians risk intermediate nonhispanic whites latinos adjustment sociodemographics diabetesrelated complications markers clinical control explain observed differences future studies investigate differences exist ways reduce