Katherine Bailey, Julia Avolio, Lisha Lo, Amy Gajaria, Sarah Mooney, Katelyn Greer, Heather Martens, Perrine Tami, Jacklynn Pidduck, Jessie Cunningham, Sarah Munce, Alene Toulany
Social and Structural Drivers of Health and Transition to Adult Care
Pediatrics
systematic reviews srs could offer best evidence supporting interventions methodological flaws limit trustworthiness decisionmaking crosssectional study appraised methodological quality srs atopic dermatitis ad treatments searched medline embase psycinfo cochrane database srs ad treatments published 20192022 extracted srs bibliographical data appraised srs methodological quality amstar measurement tool assess systematic reviews 2 explored associations methodological quality bibliographical characteristics among 52 appraised srs one 19 high methodological quality 45 865 critically low critical domains five 96 employed comprehensive search strategy seven 135 provided list excluded studies 17 327 considered risk bias primary studies 21 404 contained registered protocol 24 462 investigated publication bias cochrane reviews sr updates srs european corresponding authors srs funded european institutions better overall quality impact factor author number positively associated overall quality methodological quality srs ad treatments unsatisfactory future reviewers improve critical methodological aspects resources devolved upscaling evidence synthesis infrastructure improving critical appraisal skills evidence users