Cindy Faust, Pascal Auquier, Virginie Gandemer, Yves Bertrand, Marie-Dominique Tabone, Sophie Ansoborlo, André Baruchel, Jacinthe Bonneau, Jean-Hugues Dalle, Pascal Chastagner, Justyna Kanold, Maryline Poirée, Alexandre Theron, Laura Olivier, Isabelle Pellier, Gérard Michel, Julie Berbis
Educational outcomes in siblings of childhood leukemia survivors: Factors associated with school difficulties and comparison with general population
Cancer medicine
leucocyte telomere length ltl linked accelerate aging premature mortality research aimed explore relations biochemical anthropometry markers ltl asian indian women abnormal fasting glycemia impaired fasting glucose study 797 prediabetic women obese 492 nonobese 305 recruited demographic clinical profiles anthropometry fasting blood glucose evaluated ltl quantified quantitative pcr ltl expressed relative telomere length telomere repeatsingle copy gene ts ratio subjects separated quartiles according ltl average ltl significantly decreased increasing age average ltl significantly shorter obese women abnormal fasting glycemia p005 rsquared r2 statistic multivariable linear model adjusted age family income education hypertension showed ltl inversely correlated body mass index bmi waist hip circumference waisthip waisttoheight ratio truncal skinfolds subscapular subscapulartriceps ratio central total skinfolds fat mass kg body fat relationship obesity measures ltl using ltl quartile 1 reference identified central skinfolds r2092 p00001 4sf r2090 p00001 bmi r2093 p00001 body fat r2091 p00001 independent predictors ltl besides age obesity subcutaneous adiposity predominantly truncal major contributors telomere shortening asian indian women abnormal fasting glycemia impaired fasting glucose