Imdad Ullah, Muhammad Zaheer Asghar, Elena Barbera, Meltem Cimen
Integrating social media-based community of inquiry with theory of planned behavior to promote equitable educational intentions among pre-service teachers in Gilgit Baltistan, Pakistan
Frontiers in psychology
microbial signatures emerged promising biomarkers disease diagnostics prognostics yet variability across different studies calls standardized approach biomarker research therefore introduce xmarkerfinder fourstage computational framework microbial biomarker identification comprehensive validations crosscohort datasets including differential signature identification model construction model validation biomarker interpretation xmarkerfinder enables identification validation reproducible biomarkers crosscohort studies along establishment classification models potential microbiomeinduced mechanisms originally developed gut microbiome research xmarkerfinders adaptable design makes applicable various microbial habitats data types distinct existing biomarker research tools typically concentrate singular aspect xmarkerfinder uniquely incorporates sophisticated feature selection process specifically designed address heterogeneity different cohorts extensive internal external validations detailed specificity assessments execution time varies depending sample size selected algorithm computational resource accessible via github httpsgithubcomtjcadd2020xmarkerfinder xmarkerfinder supports users diverse expertise levels different execution options including steptostep scripts detailed tutorials frequently asked questions singlecommand execution script readytouse docker image userfriendly web server httpswwwbiosinoorgxmarkerfinder