Kimberly A. Kaphingst|Jewel D. Stafford|Lucy D’Agostino McGowan|Joann Seo|Christina Lachance|Melody S. Goodman
Effects of racial and ethnic group and health literacy on responses to genomic risk information in a medically underserved population.
National Human Genome Research Institute|National Institutes of Health
studies examined individuals respond genomic risk information common chronic diseases randomized study examined differences responses type genomic information genetic testfamily history disease condition diabetesheart disease raceethnicity medically underserved population1057 englishspeaking adults completed survey containing 1 4 vignettes 2by2 randomized design differences dependent variables ie interest receiving genomic assessment discussing doctor family changing health habits experimental condition raceethnicity examined using chisquared tests multivariable regression analysisno significant differences found dependent variables type genomic information disease condition multivariable models hispanics interested receiving genomic assessment whites 193 p 0001 respondents marginal 154 p 005 limited 185 p 009 health literacy greater interest adequate health literacy blacks 178 p 001 hispanics 185 p 001 greater interest discussing information family whites nonhispanic blacks 145 p 04 greater interest discussing genomic information doctor whites blacks 041 p 001 hispanics 025 p 033 intended change fewer health habits whites health literacy negatively associated number health habits participants intended changefindings suggest raceethnicity may affect responses genomic risk information additional research could examine cognitive representations information differ across racialethnic groups health literacy also critical consider developing approaches communicating genomic information