Ari J. Elliot|Nicholas A. Turiano|Benjamin P. Chapman
Socioeconomic Status Interacts with Conscientiousness and Neuroticism to Predict Circulating Concentrations of Inflammatory Markers
University of Rochester|West Virginia University|University of Rochester Medical Center|University of Rochester
socioeconomic health disparities research may benefit consideration dispositional factors potentially modifying risk associated low socioeconomic status including indexed systemic inflammationthis study conducted investigate interactions ses fivefactor model ffm personality traits predicting circulating concentrations inflammatory markers interleukin6 il6 creactive protein crpusing sample middleaged older adults midlife united states survey midus biomarker project n 978 linear regression models tested interactions ffm trait composite measure ses predicting il6 crp well explanatory role medical morbidity measures adiposity health behaviorsses interacted conscientiousness predict levels il6 interaction b 03 p 002 crp interaction b 04 p 014 neuroticism predict il6 interaction b 03 p 004 socioeconomic gradients markers smaller higher levels conscientiousness conversely socioeconomic gradient il6 larger higher levels neuroticism viewed perspective ses moderator neuroticism positively related il6 low levels ses negatively related high ses interactions ses conscientiousness neuroticism attenuated upon adjustment measures adiposityconscientiousness may buffer neuroticism amplify excess inflammatory risk associated low ses part relationships adiposity neuroticism may associated lower levels inflammation high levels ses