Alexis M Porter, John J Hart, Richard R Rediske, David C Szlag
SARS-CoV-2 wastewater surveillance at two university campuses: lessons learned and insights on intervention strategies for public health guidance
Journal of water and health
thermophilic proteins important academic research industrial processes various computational methods developed identify screen however performance limited due lack highquality labeled data efficient models representing protein proposed novel sequencebased thermophilic proteins prediction framework called thermofinder results demonstrated thermofinder outperforms previous stateoftheart tools two benchmark datasets feature ablation experiments confirmed effectiveness approach additionally thermofinder exhibited exceptional performance consistency across two newly constructed datasets one specifically constructed regressionbased prediction temperature optimum values directly derived protein sequences feature importance analysis using shapley additive explanations validated advantages thermofinder believe thermofinder valuable comprehensive framework predicting thermophilic proteins made model open source available github httpsgithubcomluosynbiolabthermofinder