Francis Bajunirwe|Jessica Haberer|Yap Boum|Peter W. Hunt|Rain A. Mocello|Jeffrey N. Martin|David R. Bangsberg|Judith A. Hahn
Comparison of Self-Reported Alcohol Consumption to Phosphatidylethanol Measurement among HIV-Infected Patients Initiating Antiretroviral Treatment in Southwestern Uganda
Mbarara University of Science and Technology|Harvard University|Epicentre Uganda|University of California, San Francisco|University of California, San Francisco|University of California, San Francisco|Harvard University|University of California, San Francisco
background alcohol consumption among hivinfected patients may accelerate hiv disease progression reduce antiretroviral therapy adherence selfreported alcohol use frequently underreported due social desirability recall bias aim study compare selfreported alcohol consumption phosphatidylethanol peth biomarker alcohol consumption estimate correlation multiple measures selfreported alcohol consumption peth methods uganda aids rural treatment outcomes uarto cohort located southwestern uganda follows patients art measure treatment outcomes patients complete standardized questionnaires quarterly including questions demographics health status alcohol consumption baseline dried blood spots dbs collected retrieved measure peth results one hundred fifty samples tested 56 373 peth positive 8 ngml 517 report alcohol use past month men likely underreport compared women 29 95 ci 126 665 higher economic asset categories less likely underreport compared lowest category 041 95 ci 017 094 among selfreported drinkers n 31 peth highly correlated total number drinking days last 30 spearman r 073 p0001 conclusions approximately half hiv infected patients initiating art consuming alcohol underreport use alcohol given high prevalence clinicians assess patients alcohol use attention males lower economic asset categories deny alcohol use among reporting current drinking selfreported drinking days useful quantitative measure