Qing Lan|Xingzhou He|Min Shen|Linwei Tian|Larry Z. Liu|Hong Li|Wei Chen|Sonja I. Berndt|H. Dean Hosgood|Eunil Lee|Tongzhang Zheng|Aaron Blair|Robert S. Chapman
Variation in lung cancer risk by smoky coal subtype in Xuanwei, China
United States Department of Health and Human Services|National Cancer Institute|Chinese Center For Disease Control and Prevention|United States Department of Health and Human Services|National Cancer Institute|Chinese University of Hong Kong|Cornell University|Johns Hopkins University|United States Department of Health and Human Services|National Cancer Institute|United States Department of Health and Human Services|National Cancer Institute|United States Department of Health and Human Services|National Cancer Institute|Yale University|National Cancer Institute|United States Department of Health and Human Services|Chulalongkorn University
lung cancer rates xuanwei county among highest china males females causally associated exposure indoor smoky bituminous coal emissions contain high levels polycyclic aromatic hydrocarbons numerous coal mines across county although lung cancer risk strongly associated use smoky coal whole variation risk smoky coal subtype characterized yet conducted populationbased casecontrol study 498 lung cancer cases 498 controls individually matched case subjects age 2 years sex examine risk coal subtype odds ratios ors 95 confidence intervals cis coal subtype calculated conditional logistic regression adjusting potential confounders overall smoky coal use positively statistically significantly associated lung cancer risk compared use smokeless coal wood 77 95 ci 45133 furthermore marked heterogeneity risk estimates specific subtypes smoky coal test heterogeneity p 517 x 1010 estimates highest coal laibin 248 95 ci 124496 longtan 116 95 ci 50272 coal types lower coal subtypes findings strongly suggest xuanwei elsewhere carcinogenic potential coal combustion products exhibit substantial local variation specific coal source