Tessa Watts, Nicholas Courtier, Sarah Fry, Nichola Gale, Elizabeth Gillen, Grace McCutchan, Manasi Patil, Tracy Rees, Dominic Roche, Sally Wheelwright, Jane Hopkinson
Access, acceptance and adherence to cancer prehabilitation: a mixed-methods systematic review
Journal of cancer survivorship : research and practice
although extremely premature birth disrupts lung development adolescent survivors extreme prematurity show good clinical physiologic outcomes cardiopulmonary limitations may clinically evident rest data regarding exercise limitation adolescents following preterm birth postsurfactant era limited longterm effects bronchopulmonary dysplasia bpd extreme prematurity 29 weeks ventilatory response exercise adolescents postsurfactant era followed longitudinally recruited cohort children aged 1319 years born gestational age 29 weeks study group sg compared cardiopulmonary exercise testing cpet results without bpd cpet results elementary school age mean 909 105 years thirtyseven children aged 1573 131 years mean gestational age 26 weeks 119 completed study cpet parameters adolescence within normal range age including mean vo2 peak 91 predicted bpd nonbpd subgroups similar results longitudinal analysis sg improvement observed adolescence compared elementary school age breathing reserve 3637 1899 vs 2658 1792 p 0044 tidal volume fraction vital capacity achieved maximal load 051 013 vs 037 008 p 0001 respiratory exchange ratio maximal load 118 013 vs 111 010 p 0021 current cohort adolescents born extremely premature essentially normal ventilatory response exercise unrelated bpd diagnosis cpet results population improve time