Ana Joaquim, Cláudia Vieira, Leonor Ribeiro, Anabela Barros, Inês Leão, Cecília Alvim, Sara Pinheiro, Mafalda Nogueira, Catarina Morais
Head and neck cancer patient journey's health literacy: a multidisciplinary team perspective. VOICE study
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
computational methods desired singlecellresolution spatial transcriptomics st data analysis uncover spatial organization principles individual cells exert tissuespecific functions present st data analysis via interactionaware cell embedding space deeplearning method celltype identification tissue module discovery singlecellresolution st data learning cell representation captures gene expression profile interactions spatial neighbors space identified spatially informed cell subtypes defined special spatial distribution patterns distinct proximalinteracting cell types space also automatically discovered cell communitiestissue modules discernible boundaries uniform spatial distribution constituent cell types cell community space outputs characteristic proximal cellcell interaction network associated physiological processes used refine ligandreceptorbased intercellular signaling analyses envision space used largescale st projects understand proximal cellcell interactions contribute emergent biological functions within cell communities record papers transparent peer review process included supplemental information