W Taylor Martin, Morgan Bonds, Laura Fischer, Katherine T Morris, Zoona Sarwar, Kenneth Stewart, Tabitha Garwe, Alessandro Paniccia, Richard D Schulick, Ajay Jain, Barish H Edil
Learning Curve of a Laparoscopic Pancreaticoduodenectomy Program at a Second Institution
The American surgeon
despite proven efficacy increased availability therapeutic plasma exchange thrombotic thrombocytopenic purpura ttp associated significant morbidity mortality study utilized kids inpatient database national inpatient sample 2003 2016 study predictors inhospital mortality hospitalized ttp patients adjusted odds ratios death various putative risk factors calculated using multiple regression analysis among 1568 hospitalizations ttp primary admission diagnosis underwent therapeutic plasma exchange 69 deaths identified allcause mortality 004 median timetodeath 6 wk overall hospitalizations rates fairly similar across study period overall incidence ttp related hospitalizations 151 per 100000 hospitalizations total 69 deaths reported allcause inhospital mortality rate 004 691568 median timetodeath 6 weeks majority deaths occurred age 16 20 years 58 females 565 african american 429 shown table 2 mean age nonsurvivors 14 years mean age 15 years survivors p001 younger age male sex africanamerican ethnicity malignancy sepsis acute kidney injury platelet transfusion significantly associated mortality patients ttp early targeted therapy high risk individuals used guide management ttp patients improved survival outcomes