Danielle L. Beatty Moody|Charlotte Brown|Karen A. Matthews|Joyce T. Bromberger
Everyday Discrimination Prospectively Predicts Inflammation across 7?Years in Racially Diverse Midlife Women: Study of Women's Health across the Nation
University of Maryland, Baltimore County|University of Pittsburgh|University of Pittsburgh|University of Pittsburgh
selfreported discrimination emerged predictor negative psychological physical health outcomes across racialethnic groups goals study determine whether creactive protein crp marker inflammation risk factor future cardiovascular disease cvd independently predicted everyday discrimination whether race body mass index bmi modified association 7year period among 2490 women racially diverse backgrounds baseline 10item williams measure everyday discrimination administered generalized estimating equations used assess associations descriptive results showed black chinese women reported greater discrimination white japanese hispanic women black hispanic women highest levels crp 7year period main effect everyday discrimination b 003 se 005 p 58 association differ function race p gt 05 everyday discrimination bmi interaction term significantly predicted higher crp levels time full sample women p 03 specifically nonobese women bmi less 30 higher perceived everyday discrimination associated higher crp levels 7year period findings independent demographic negative affect biomedical behavioral factors results demonstrate greater everyday discrimination associated increased inflammation time nonobese women findings highlight implications interpersonal sources social stress longterm physical health via impact intermediary biological pathways specifically inflammation greater emphasis linkages warranted work towards ameliorating health disparities exacerbated individuallevel factors