Jiménez-Corona Me
Gender differentials of pulmonary tuberculosis transmission and reactivation in an endemic area
Instituto Nacional de Salud Pública
bbackgroundb low income countries twice many cases tuberculosis tb reported among men among women difference commonly attributed biological epidemiological characteristics well socioeconomic cultural barriers access health care world health organization encouraged gender specific comparisons tb rates determine whether women tb less likely men tb diagnosed reported treated study undertaken identify gender based differences patients pulmonary tb use information improve tb control efforts bmethodsb individuals cough 2 weeks southern mexico screened march 1995 april 2003 clinical mycobacteriological information isolation identification drug susceptibility testing isi6110i based genotyping spoligotyping collected bacteriologically confirmed pulmonary tb patients treated accordance official norms followed ascertain treatment outcome retreatment vital status bresultsb 623 patients pulmonary tb enrolled malefemale incidence rate ratio overall reactivated recently transmitted disease 158 95 ci 134 186 164 95 ci 136 198 141 95 ci 101 196 respectively men likely women default treatment adjusted 330 95 ci 146 743 retreated hazard ratio hr 315 95 ci 138 722 die tb hr 223 95 ci 125 399 bconclusionsb higher rates transmitted reactivated disease poorer treatment outcomes among men indicators gender differentials diagnosis treatment pulmonary tb suggest specific strategies endemic settings