Daniela Romano, Antonella Bernetti, Riccardo De Lauretis
Different methodologies to quantify uncertainties of air emissions
Environment international
largescale cortical dynamics play crucial role many cognitive functions goaldirected behaviors motor learning sensory processing well established brain states including wakefulness sleep anesthesia modulate neuronal firing synchronization within across different brain regions however brain state affects cortical activity mesoscale level less understood work aimed identify cortical regions engaged different brain states end employed group ica independent component analysis widefield imaging recordings cortical activity mice different anesthesia levels awake state thanks approach identified independent components ics representing elements cortical networks common across subjects decreasing levels anesthesia toward awake state found ics related retrosplenial cortices exhibited pronounced dependence brain state prevalent deeper anesthesia levels diminishing transition awake state analyzing occurrence ics found activity deeper anesthesia states characterized strong correlation retrosplenial components correlation decreases transitioning toward wakefulness overall results indicate deeper anesthesia states coactivation posteriormedial cortices predominant connectivity patterns whereas richer repertoire dynamics expressed lighter anesthesia levels awake state