Nasar Ahmad Shayan, Ali Rahimi, Saverio Stranges, Amardeep Thind
Exploring Sex Differences in Risk Factors and Quality of Life Among Tuberculosis Patients in Herat, Afghanistan: A Case-Control Study
International journal of public health
objective study investigate associated risk factors pulmonary infection individuals diagnosed chronic kidney disease ckd primary goal develop predictive model anticipate likelihood pulmonary infection hospitalization among ckd patients retrospective cohort study conducted two prominent tertiary teaching hospitals three distinct models formulated employing three different approaches 1 statisticsdriven model 2 clinical knowledgedriven model 3 decision tree model simplest efficient model obtained comparing predictive power stability practicability study involved total 971 patients 388 individuals comprising modeling group 583 individuals comprising validation group three different models namely models b c utilized resulting identification seven four eleven predictors respectively ultimately statistical knowledgedriven model selected exhibited cstatistic 0891 08550927 brier score 0012 furthermore hosmerlemeshow test indicated model demonstrated good calibration additionally model displayed satisfactory cstatistic 0883 08560911 external validation statisticaldriven model known ac2gh2s risk score incorporates factors albumin c2 previous copd history blood calcium random venous blood glucose h2 hemoglobin highdensity lipoprotein smoking utilized determine risk score incidence rate lung infection patients ckd findings revealed gradual increase occurrence pulmonary infections ranging 184 individuals ac2gh2s risk score 6 9396 ac2gh2s risk score 185 predictive model comprising seven predictors developed forecast pulmonary infection patients ckd model characterized simplicity practicality also good specificity sensitivity verification