Nathan H Varady, Ayoosh Pareek, Christina M Eckhardt, Riley J Williams, Sophia J Madjarova, Matthieu Ollivier, R Kyle Martin, Jón Karlsson, Benedict U Nwachukwu
Multivariable regression: understanding one of medicine's most fundamental statistical tools
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
recent cochrane review reality orientation therapy identified need large welldesigned multicentre trialsto test hypothesis cognitive stimulation therapy cst older people dementia would benefit cognition quality lifea singleblind multicentre randomised controlled trial recruited 201 older people dementia main outcome measures change cognitive function quality life intentiontotreat analysis used analysis covariance control potential variability baseline measuresone hundred fifteen people randomised within centres intervention group 86 control group followup intervention group significantly improved relative control group minimental state examination p0044 alzheimers disease assessment scale cognition adascog p0014 quality life alzheimers disease scales p0028 using criteria 4 points improvement adascog number needed treat 6 intervention groupthe results compare favourably trials drugs dementia cst groups may worthwhile benefits many people dementia