Fredrika Norlund|Emma Wallin|Erik Olsson|John Wallert|Gunilla Burell|Louise von Essén|Claes Held
Internet-Based Cognitive Behavioral Therapy for Symptoms of Depression and Anxiety Among Patients With a Recent Myocardial Infarction: The U-CARE Heart Randomized Controlled Trial
Uppsala University|Uppsala University|Uppsala University|Uppsala University|Uppsala University|Uppsala University|Uppsala University
symptoms depression anxiety common myocardial infarction mi internetbased cognitive behavioral therapy icbt shown good results patient groupsthe aim study evaluate effectiveness icbt treatment reduce selfreported symptoms depression anxiety among patients recent miin total 3928 patients screened eligibility 25 swedish hospitals 239 patients 335 80239 women mean age 60 years recent mi symptoms depression anxiety randomly allocated therapistguided 14week icbt treatment n117 treatment usual tau n122 icbt treatment designed postmi patients primary outcome total score hospital anxiety depression scale hads 14 weeks post baseline assessed internet treatment effect evaluated according intentiontotreat principle multiple imputations main analysis pooled treatment effect estimated controlling age sex baseline hadsthere reduction hads scores time total study sample mean delta51 p001 difference study groups followup beta047 95 ci 195 100 p53 treatment adherence low total 462 54117 icbt group complete introductory moduleicbt treatment mi population result lower levels symptoms depression anxiety compared tau low treatment adherence might influenced resultclinicaltrialsgov nct01504191 httpsclinicaltrialsgovct2shownct01504191 archived webcite httpwwwwebcitationorg6xwwseq22