K Hynes|Petr Otáhal|Ian Hay|John Burgess
Mild Iodine Deficiency During Pregnancy Is Associated With Reduced Educational Outcomes in the Offspring: 9-Year Follow-up of the Gestational Iodine Cohort
University of Tasmania|University of Tasmania|Royal Hobart Hospital
severe iodine deficiency id gestation associated neurocognitive sequelae longterm impact mild id however well characterizedthe purpose study determine whether children born mothers urinary iodine concentrations uics 150 gl pregnancy poorer educational outcomes primary school peers whose mothers gestational id uic 150 glthis longitudinal followup 9 years old gestational iodine cohort pregnancy occurred period mild id population children subsequently growing iodinereplete environmentparticipants children whose mothers attended royal hobart hospital tasmania antenatal clinics 1999 2001australian national curriculum tasmanian state curriculum educational assessment data children year 3 analyzedchildren whose mothers uic 150 gl reductions 100 spelling 411 points 95 confidence interval ci 680 143 p 003 76 grammar 309 points 95 ci 602 17 p 038 57 englishliteracy 033 points 95 ci 063 003 p 034 performance compared children whose mothers uics 150 gl associations remained significant adjustment range biological factors maternal age birth child gestational length time birth gestational age time urinary iodine collection birth weight sex differences spelling remained significant adjustment socioeconomic factors maternal occupation educationthis study provides preliminary evidence even mild iodine deficiency pregnancy longterm adverse impacts fetal neurocognition ameliorated iodine sufficiency childhood