Tsuguhiko Kato, Kotaro Aoki
[Association between home environment and children's long hours of internet use: An analysis of Survey on Parent-child Relationship in the Internet Age]
[Nihon koshu eisei zasshi] Japanese journal of public health
review normally occurring neuronal patterns hippocampus suggests two principal cell types hippocampus pyramidal neurons granule cells maximally active different behaviors granule cells reach highest discharge rates thetaconcurrent exploratory activities population synchrony pyramidal cells maximum immobility consummatory behaviors slow wave sleep associated field sharp waves sharp waves reflect summed postsynaptic depolarization large numbers pyramidal cells ca1 subiculum consequence synchronous discharge bursting ca3 pyramidal neurons trigger population burst ca3 region temporary release subcortical tonic inhibition overview experimentally explored criteria synaptic enhancement intensity frequency pattern postsynaptic depolarization calcium influx cooperativity threshold suggests requirements may present sharp waveconcurrent population bursts pyramidal cells experimental evidence cited showing population bursts ca3 may lead longterm potentiation postsynaptic ca1 targets b tetanizing stimuli capable increasing synchrony sharp waveburst c activity patterns neocortical input hippocampus determine subgroup ca3 neurons trigger subsequently occurring population bursts initiator cells based experimental evidence reviewed formal model memory trace formation outlined exploratory theta behaviors neocortical information transmitted hippocampus via fastfiring granule cells may induce weak transient heterosynaptic potentiation subgroup ca3 pyramidal cells weakly potentiated ca3 neurons initiate population bursts upon termination exploratory activity sharp wave state assumed recurrent excitation population burst strongest cells initiated population event suggested strong excitatory drive brought sharp waveconcurrent population bursts consummatory behaviors immobility slow wave sleep may sufficient induction longterm synaptic modification initiator neurons ca3 region targets ca1 twostage model exploratory theta sharp wave states hippocampus essential interference might modify structure population bursts eg epileptic spikes detrimental memory trace formation