Robert J Cramer, Lewis J Peiper, Andrea R Kaniuka, Franck Diaz-Garelli, Justin C Baker, Ryan A Robertson
Development of the Self-Injury Risk Assessment Protocol for Corrections (SIRAP-C)
Law and human behavior
somatostatin receptor positron emission tomographycomputed tomography sstrpetct using 68galabeled tracers widely used imaging modality neuroendocrine tumors net recently 18fsitate sifalin tagged tyr3octreotate tate pet tracer shown great potential due favorable clinical characteristics aimed evaluate reproducibility somatostatin receptorreporting data system 10 sstrrads 10 structured interpretation treatment planning net using 18fsitate four readers assessed 18fsitatepetct 95 patients according sstrrads 10 criteria two different time points reader evaluated five target lesions per scan overall scan score decision peptide receptor radionuclide therapy prrt considered inter intrareader agreement determined using intraclass correlation coefficient icc icc analysis interreader agreement using sstrrads 10 identical target lesions icc 85 overall scan score icc 90 decision recommend prrt icc 85 showed excellent agreement however significant differences observed recommending prrt among experienced readers er p 0020 inexperienced readers ir p 0004 compartmentbased analysis demonstrated good excellent interreader agreement organs icc 74 except lymph nodes icc 53 sstrrads 10 represents highly reproducible consistent framework system stratifying sstrtargeted petct scans even using novel sstrligand 18fsitate interreader variability observed regarding evaluation uptake intensity prior prrt well compartment scoring lymph nodes indicating categories require special attention clinical validation might refined future sstrrads version 11 sstrrads 10 consistent framework categorizing somatostatin receptortargeted petct scans using 18fsitate framework serves valuable tool facilitating improving management patients net sstrrads 10 valuable tool managing patients net sstrrads 10 categorizes patients showing strong agreement across diverse reader expertise alternative 68galabeled petct neuroendocrine tumor imaging sstrrads 10 reliably classifies 18fsitatepetct