Mariela Mosheva, Virginie Pouillard, Yael Fishman, Lydia Dubourg, Dafna Sofrin-Frumer, Yaffa Serur, Abraham Weizman, Stephan Eliez, Doron Gothelf, Maude Schneider
Education and employment trajectories from childhood to adulthood in individuals with 22q11.2 deletion syndrome
European child & adolescent psychiatry
schoolsupervised use oncedaily inhaled corticosteroid regimen supervised therapy improve medication adherence asthma control sought evaluate effectiveness supervised therapy unique setting population conducted cluster randomized trial supervised therapy 20 elementary schools disproportionate enrollment lowincome latino students schools purposively selected matched randomized receive 9 months supervised therapy mometasone furoate usual care english spanishspeaking students selfreported asthma eligible asthma control questionnaire acq interviewer administered quarterly school students supervised therapy schools hypothesized lower acq scores students usualcare schools 393 enrolled students 189 students receiving immediate intervention 143 students receiving delayed intervention provided 1 acq data points 6 10 years age included primary analysis baseline 39 students reported taking controller medication 24 wellcontrolled asthma eighty percent students receiving immediate intervention prescribed mometasone schools administered 98 prescribed doses students attended school absences weekends holidays reduced calendar adherence 53 first year mean acq score students receiving immediate delayed intervention 155 95 ci 141170 164 95 ci 147180 respectively estimated treatment effect 008 95 ci 031 014 compared usual care supervised therapy improve asthma control among population latino students additional research warranted confirm results