Lea D Nielsen, Mette M Løwe, Francisco Mansilla, Rene B Jørgensen, Asviny Ramachandran, Bodil B Noe, Heidi K Egebæk
Interventions, methods and outcome measures used in teaching evidence-based practice to healthcare students: an overview of systematic reviews
BMC medical education
motor learning essential performing specific tasks progresses distinct stages including rapid learning phase initial skill acquisition consolidation phase skill refinement stable performance phase skill mastery maintenance understanding cortical activation dynamics stages guide targeted rehabilitation interventions longitudinal randomized controlled trial functional nearinfrared spectroscopy used explore temporal dynamics cortical activation handrelated motor learning thirtyone healthy righthanded individuals randomly assigned perform either easy intricate motor tasks nondominant hand 10 days conducted 10 monitoring sessions track cortical activation right hemisphere according lateralization principles primary hemisphere motor control evaluated motor proficiency concurrently study delineated three stages nondominant hand motor learning rapid learning days 1 2 consolidation days 37 stable performance days 810 powerlaw enhancement motor skills correlated learning progression sustained activation observed supplementary motor area sma parietal lobe pl whereas activation right primary motor cortex m1r dorsolateral prefrontal cortex pfcr decreased cortical activation patterns exhibited high correlation augmentation motor proficiency findings suggest early rehabilitation interventions transcranial magnetic stimulation transcranial direct current stimulation tdcs could optimally directed m1 pfc initial stages contrast sma pl targeted throughout motor learning process research illuminates path developing tailored motor rehabilitation interventions based specific stages motor learning innovative approach study uniquely combines longitudinal design robustness generalized estimating equations gees synergy functional nearinfrared spectroscopy fnirs minnesota manual dexterity test mmdt paradigm precisely trace evolution neural resources complex realworld finemotor task learning centering righthanded participants using nondominant hand magnifies intricacies right hemisphere spatial motor processing unravel brains dynamic response throughout motor learning stages potent link motor skill enhancement significantly data point toward earlyphase rehabilitation potential tms transcranial direct current stimulation m1 pfc regions concurrently sma pl appear poised benefit ongoing interventions entire learning curve findings carve path refined motor rehabilitation strategies underscoring importance timely noninvasive brain stimulation treatments