Rajesh Kumar|Laura M. Curtis|Sanjay Khiani|James N. Moy|Madeleine U. Shalowitz|Lisa K. Sharp|Ramón Durazo-Arvizú|John J. Shannon|Kevin B. Weiss
A community-based study of tobacco smoke exposure among inner-city children with asthma in Chicago
Lurie Children's Hospital|Northwestern University|Rush University|Rush University|Northwestern University|University of Illinois at Chicago|Loyola University Medical Center|John H. Stroger, Jr. Hospital of Cook County|Northwestern University|Edward Hines, Jr. VA Hospital
little known level tobacco exposure factors influence exposure children persistent asthmawe sought measure tobacco smoke exposure determine factors associated exposure large urban sample asthmatic childrenthis crosssectional study based communitybased cohort 482 children 814 years old persistent asthma caregiver household tobacco use reported caregiver child tobacco smoke exposure assessed using salivary cotinine level multivariate linear regression logtransformed salivary cotinine levels used characterize relationship smoke exposure caregiver household demographic characteristics used multivariate logistic model characterize associations caregiver smokingoverall 685 children tobacco smoke exposure compared nonexposed children exposed smoking caregiver another household member cotinine levels 168 95 ci 145194 140 95 ci 122162 times higher respectively compared hispanic children african american whiteother children 155 95 ci 116206 159 95 ci 118214 times higher cotinine levels respectively child exposure also associated caregiver depression symptoms odds ratio 101 95 ci 101102 higher household income protective odds ratio 073 95 ci 056095 independent predictors caregiver smoking included protective effect higher education odds ratio 035 95 ci 015083 positive association potential problematic drugalcohol use odds ratio 230 95 ci 139383tobacco smoke exposure high urban sample asthmatic children caregiver smoking strongly associated child exposure also associated lower socioeconomic status nonhispanic ethnicity depression symptoms