D Newton, J Stephenson, L Azevedo, R K Sah, A N Poudel, O Richardson
The impact of social determinants on health outcomes in a region in the North of England: a structural equation modelling analysis
Public health
objective describe trends annual prevalence hospitalization pediatric acute mastoiditis since introduction 7valent pneumococcal vaccine 2000 13valent vaccine 2010 crosssectional retrospective data analysis kids inpatient database years 2000 2012 analyzed determine annual prevalence hospitalization acute mastoiditis nationally weighted frequencies hospitalization children 21 years acute mastoiditis diagnoses collected trend analysis hospitalization rates 2000 2012 performed 2000 2012 significant trend hospitalization rates acute mastoiditis overall 138 143 per 100000 persons 2000 2012 respectively p 86 age group comparing hospitalization rates time points 2000 2012 children 1 year 465 327 per 100000 persons p 0023 1 2 years age 395 318 per 100000 persons respectively p 0107 demonstrated declines hospitalization time 2009 2012 hospitalization rates also significantly declined children aged 1 year 450 327 per 100000 persons p 0056 1 2 years 430 318 per 100000 persons p 0002 increased children 5 9 years 110 181 per 100000 persons p 0001 10 20 years age 041 072 per 100000 persons p 0001 despite introduction two pneumococcal vaccines rates hospitalization pediatric acute mastoiditis decline 2000 2012 2009 2012 however children 0 2 years age showed declining hospitalization rates possibly reflecting protective benefit 13valent pneumococcal vaccine 4 laryngoscope 12814801485 2018