Heather Marriott, Renata Kabiljo, Ahmad Al Khleifat, Richard J Dobson, Ammar Al-Chalabi, Alfredo Iacoangeli
DNAscan2: a versatile, scalable, and user-friendly analysis pipeline for human next-generation sequencing data
Bioinformatics (Oxford, England)
study seeks evaluate recent covid19 infection affects myocardial perfusion functional parameters derived gated myocardial perfusion imaging patients undergoing evaluation coronary artery disease goal enhance understanding covid19s influence cardiovascular system conducted farshchian heart hospital 2022 2023 casecontrol study enrolled patients suspected coronary artery disease stratified two groups confirmed covid19 infection within past 6 months study group without prior covid19 infection control group employing 2day protocol stress testing gated spect mpi performed statistical analysis included descriptive statistics chisquare test students test mannwhitney u test among 86 patients included 43 group significantly higher summed stress core summed difference score values observed study group compared control group p 005 addition study group exhibited significantly altered global left ventricular ejection fraction enddiastolic volume endsystolic volume p 005 nonperfusion findings including transient ischemic dilation transient right ventricular visualization prevalent study group recent covid19 infection associated impaired myocardial perfusion altered functional parameters detected mpi findings underscore intricate interplay covid19 cardiovascular health emphasizing importance comprehensive evaluation management strategies address cardiac complications affected individuals research warranted elucidate underlying mechanisms optimize patient care context covid19associated cardiovascular manifestations