Joe Hulin, Vyv Huddy, Phillip Oliver, Jack Marshall, Aarti Mohindra, Brigitte Delaney, Caroline Mitchell
Experiences of support for people who access voluntary, community and social enterprise (VCSE) organisations for self-harm: a qualitative study with stakeholder feedback
BMC public health
alzheimers disease related dementias adrd affect 55 million globally current clinical trials suffer low recruitment rates challenge potentially addressable via natural language processing nlp technologies researchers effectively identify eligible clinical trial participants study investigates sociotechnical feasibility nlpdriven tools adrd research prescreening analyzes tools cognitive complexitys effect usability identify cognitive support strategies randomized experiment conducted 60 clinical research staff using three prescreening tools criteria2query informatics integrating biology bedside i2b2 leaf cognitive task analysis employed analyze usability tool using health information technology usability evaluation scale data analysis involved calculating descriptive statistics interrater agreement via intraclass correlation coefficient cognitive complexity generalized estimating equations models leaf scored highest usability followed criteria2query i2b2 cognitive complexity found affected age computer literacy number criteria significantly associated usability adopting nlp adrd prescreening demands careful task delegation comprehensive training precise translation eligibility criteria increased research accessibility study highlights relevance factors enhancing nlpdriven tools usability efficacy clinical research prescreening usermodifiable nlpdriven prescreening tools favorably received system type evaluation sequence users computer literacy influencing usability cognitive complexity study emphasizes nlps potential improving recruitment clinical trials endorsing mixedmethods approach future system evaluation enhancements