Claudia Pimentel-Hernández, José Francisco González-Zamora, José Humberto Medina-Cortina, Silvestre García-de la Puente, José Luis Arredondo-García
Effectiveness of an educational strategy to increase plain water consumption in children
Salud publica de Mexico
risk stratification based prediction models become increasingly important preventing managing chronic diseases however due cost timelimitations every population resources collecting enough detailed individuallevel information large number people develop risk prediction models practical approach use prediction models developed existing studies calibrate relevant summarylevel information target population many existing studies conducted populationbased casecontrol design gail et al j natl cancer inst 8118791886 1989 proposed combine odds ratio estimates obtained casecontrol data disease incidence rates target population obtain baseline hazard function thereby pure risk developing diseases however approach requires risk factor distribution cases casecontrol studies target population violated may yield biased risk estimation article propose two novel weighted estimating equation approaches calibrate baseline risk leveraging summary information risk factors addition diseasefree probabilities targeted population establish consistency asymptotic normality proposed estimators extensive simulation studies application colorectal cancer studies demonstrate proposed estimators perform well bias reduction finite samples