Gary Toedter, Katherine Li, Sarah Sague, Keying Ma, Colleen Marano, Michael Macoritto, Jennifer Park, Renée Deehan, Andrea Matthews, Gary D Wu, James D Lewis, Ingrid Arijs, Paul Rutgeerts, Frédéric Baribaud
Genes associated with intestinal permeability in ulcerative colitis: changes in expression following infliximab therapy
Inflammatory bowel diseases
joint replacement successful endstage osteopathy obesity linked evaluated risk impact obesity selfreported health exercise capacity among joint replacement patients remains complex requires investigation study utilizes data national health nutrition examination survey nhanes examine relationship obesity severity demographic factors medical comorbidities selfreported health status relationship general health status bmi analyzed using multivariable regression illustrated using restricted cubic spline additionally bibliometric analysis systemic review done frame research within broader context existing knowledge demographic specifics analysis nhanes data involving 327 joint replacement patients yielded intriguing insights difference selfreported health bmi groups achieve conventional statistical significance p006 multivariable analysis showed even severely obese patients exhibit significantly elevated risk poorfair selfreported health compared normal weight subjects among severely obese individuals bmi40 4063 still rated health positively however stratified analyses indicated obesity correlated negative health reports across gender age education strata notably physical functioning emerged robust predictor selfreported health reporting walking difficulties significantly lower odds poorfair health odds ratio037 p001 study highlights need healthcare providers consider individual physical abilities comorbidities alongside obesity severity discussing treatment options joint replacement patients supports tailored interventions informed shared decisionmaking future research could explore effective weight management strategies obese individuals undergoing joint replacement