Christian Simon|Janet K. Williams|Laura Shinkunas|Debra Brandt|Sandra Daack-Hirsch|Martha Driessnack
Informed Consent and Genomic Incidental Findings: IRB Chair Perspectives
University of Iowa|University of Iowa|University of Iowa|University of Iowa|University of Iowa|University of Iowa
unclear genomic incidental finding gif prospects addressed informed consent processes exploratory study topic conducted 34 purposively sampled chairs institutional review boards irbs centers conducting genomewide association studies chairs 96 reported knowledge local irb requirements regarding gifs informed consent chairs suggested consent processes address prospect study disclosure policy gifs gif management followup potential clinical significance gifs potential risks gif disclosure opportunity participants opt gif disclosure duration researchers duty disclose gifs chairs concerned participant disclosure preferences changing time inherent limitations determining scope accuracy claims gifs making consent processes longer complex irb chair stakeholder perspectives help advance informed consent efforts accommodate gif prospects