Stacey K Drury, Shannon M Wallet, Robert Maile, Philip A Efron, Alicia M Mohr, Letitia Bible
Current updates in precision and personalized medicine in sepsis and trauma
Surgery
extremely low birth weight elbw infants greater risk neurodevelopmental delay fullterm infants outcomes may compromised secondary abnormal brain development associated complications prematurity longterm cognitive outcome also reported significantly influenced postnatal factors objective study clarify effects prematurity separate environmental factors growth neurodevelopmental outcomes comparing elbw children fullterm siblings study consisted 25 elbw children subset selected larger population infants 801 g birth weight enrolled longitudinal followup project birth 25 fullterm fullweight siblings twentythree sets siblings evaluated 5 years age 2 sets 3 years age standardized medical social cognitive motor language testing physical neurodevelopmental outcomes compared groups controlling gender socioeconomic status ses followup elbw children lighter shorter smaller head circumference elbw children lower stanfordbinet iqs 85 12 mean sd 95 11 lower stanfordbinet subtests except shortterm memory quantitative reasoning lower spelling scores wide range achievement test lower peabody motor quotients 79 11 92 17 preschool language scale quotients different receptive language measures lower elbw children high ses seemed modify impact preterm status cognitive language motor scores mean iq highses elbw children equivalent lowses term siblings preschoolage cognitive language functioning elbw children seemed affected prenatal birth influences preterm status postnatal influences ses variables motor scores significantly related preterm status ses