Seth C. Kalichman|Christina M. Amaral|Chauncey Cherry|Jody Flanagan|Howard Pope|Lisa A. Eaton|Moira O. Kalichman|Demetria Cain|Mervi Detorio|Angela M. Caliendo|Raymond F. Schinazi
Monitoring Medication Adherence by Unannounced Pill Counts Conducted by Telephone: Reliability and Criterion-Related Validity
University of Connecticut|University of Connecticut|University of Connecticut|University of Connecticut|University of Connecticut|University of Connecticut|University of Connecticut|University of Connecticut|Veterans Health Administration|Emory University|Veterans Health Administration|Emory University|Veterans Health Administration|Emory University
although demonstrated valid monitoring medication adherence unannounced pill counts conducted patients homes costly logistically challenging telephonebased unannounced pill counts offer promising adaptation resolves limitations homebased pill countingwe tested reliability criterionrelated validity telephonebased unannounced pill count assessment antiretroviral adherencehivpositive men women n 89 atlanta georgia completed telephonebased unannounced pill count provided contemporaneous blood specimens obtain viral loads 68 participants also received immediate second pill count conducted unannounced home visita high degree concordance observed number pills counted telephone home intraclass correlation icc 981 p 001 percent pills taken icc 987 p 001 adherence obtained telephone count home count reached 92 agreement kappa coefficient 94 adherence determined telephonebased pill counts also corresponded patient viral load providing evidence criterionrelated validityunannounced telephonebased pill counts offer feasible objective method monitoring medication adherence