Karl Peltzer|Violeta J. Rodriguez|Stephen M. Weiss|Elisa Shikwane
Promoting male involvement to improve PMTCT uptake and reduce antenatal HIV infection: a cluster randomized controlled trial protocol
Human Sciences Research Council|University of Miami|University of Miami|Human Sciences Research Council
despite availability dual therapy treatment protocol infant feeding guidelines designed prevent mother child transmission pmtct hiv 1 million babies born south africa year 70 born hiv positive mothers receive dual therapy similar resourcepoor nations facing integration pmtct routine pregnancy infant care efforts south africa scale pmtct reduce transmission 5 fallen far short united nations goal 50 reductions paediatric hiv 80 coverage mothersthis study proposes evaluate impact combining two evidencebased interventions couples risk reduction intervention evidence based medication adherence intervention enhance male participation combination improving medication pmtct adherence antenatal clinics increase pmtct overall reach effectiveness study use grouprandomized design recruiting 240 couples 12 clinics clinics randomly assigned experimental control conditions effectiveness combined intervention enhance pmtct well reduce antenatal seroconversion individuals clinics examinedshared intervention elements may decrease sexual risk enhance pmtct uptake eg increased male participation enhanced communication hiv counselling testing adherence serostatus disclosure suggest combined sexual risk reduction adherence intervention plus pmtct increase male participation increase couples communication encourage adherence pmtct process findings impact public health enable health ministry formulate policy related male involvement pmtct result pmtctpactr201109000318329