Kyra H. Grantz|Madhura S. Rane|Henrik Salje|Gregory E. Glass|Stephen E. Schachterle|Derek A. T. Cummings
Disparities in influenza mortality and transmission related to sociodemographic factors within Chicago in the pandemic of 1918
University of Florida|University of Washington|Johns Hopkins University|Institut Pasteur|University of Florida|Pfizer (United States)|University of Florida|Johns Hopkins University
social factors shown create differential burden influenza across different geographic areas explored relationship potential aggregatelevel social determinants mortality 1918 influenza pandemic chicago using historical dataset 7971 influenza pneumonia deaths census tractlevel social factors including rates illiteracy homeownership population unemployment assessed predictors pandemic mortality chicago poisson models fit generalized estimating equations gees used estimate association social factors risk influenza pneumonia mortality poisson model showed influenza pneumonia mortality increased average 322 every 10 increase illiteracy rate adjusted population density homeownership unemployment age also found significant association transmissibility population density illiteracy unemployment homeownership lastly analysis point locations reported influenza pneumonia deaths revealed finescale spatiotemporal clustering study shows living census tracts higher illiteracy rates increased risk influenza pneumonia mortality 1918 influenza pandemic chicago observation disparities structural determinants neighborhoodlevel health lead disparities influenza incidence pandemic suggests disparities determinants remain targets research control future pandemics