Sonya M Rogal, Jeanne Young
Exploring critical thinking in critical care nursing education: a pilot study
Journal of continuing education in nursing
primary objective study evaluate discriminatory utility magnetic resonance imaging mri 18ffluciclovine positron emission tomography pet maximum standardized uptake value suvmax prostatespecific antigen psa combinations diagnostic modalities detecting local prostate cancer recurrence setting rising psa radical prostatectomy patients characterised clinical features gleason score psa surgery psa followup followup mri result followup pet result followup suvmax followup disease status utility diagnostic parameters detecting disease recurrence prostatectomy bed assessed using receiver operating characteristics roc analysis determine area curve auc model sensitivity specificity positivenegative predictive values also calculated optimal cutoff points continuous variables determined based maximum youdens j statistics study found mri highest concordance 96 sensitivity 100 specificity 91 positive predictive value 93 negative predictive value 100 among diagnostic modalities auc mri 09545 indicating high discriminatory ability detecting prostate cancer local recurrence combined pet suvmax cutoff value 285 showed improved performance compared using individually auc 08925 analysis suggests mri effective imaging modality detecting local prostate cancer recurrence 18ffluciclovine pet suvmax also showing promising combined results psa moderate discriminatory utility followup still provide valuable information detecting prostate cancer recurrence research recent references needed support findings