Olivia Zahn, Jorge Bustamante, Callin Switzer, Thomas L Daniel, J Nathan Kutz
Pruning deep neural networks generates a sparse, bio-inspired nonlinear controller for insect flight
PLoS computational biology
lung cancer remains one leading cause global cancerrelated mortality posing significant burden disease tobacco exposure stands foremost risk factor lung cancer since 1960 global efforts gradually implemented control tobacco exposure consequently reducing tobacco exposure levels within populations shift exposure levels may altered epidemiological characteristics lung cancer globally study aims describe global lung cancer incidence data across five dimensions age gender region stage diagnosis survival status using global cancer registry data relevant research findings objective elucidate current epidemiological features lung cancer worldwide providing scientific basis lung cancer prevention control furthermore study offers corresponding measures recommendations lung cancer prevention control aligning threetiered cancer prevention strategy findings indicate incidence mortality burden lung cancer significantly higher among elderly population aged 65 years compared workingage population aged 1564 years agedstandardized incidence rate lung cancer remains higher males females overall agedstandardized incidence rate lung cancer males shows declining trend females shows increasing trend regions high high human development index hdi exhibit substantially higher incidence mortality burden lung cancer compared regions low low hdi japan ranks highest diagnosis stage lung cancer diagnosis rate 386 agestandardized 5year net survival rate relatively high 329 despite improvements survival status lung cancer certain countries like china japan overall prognosis lung cancer remains pessimistic given current epidemiological characteristics lung cancer reinforcing tobacco control measures reducing femalespecific lung cancer risk factors stand significant goals primary prevention promoting lowdose computed tomography screening highrisk population minimizing falsepositive rates lung cancer screening promoting medical system reforms standardized treatment constitute principal measures secondary tertiary lung cancer prevention respectively