Sabine Sayegh-Jodehl, Rebecca Mukowski-Kickhöfel, Diane Linke, Claudia Müller-Birn, Matthias Rose
Use of Instant Messaging Software in a German Hospital-An Exploratory Investigation among Physicians
International journal of environmental research and public health
study aims develop externally validate models predict probability postoperative verbal memory decline adults following temporal lobe resection tlr epilepsy using easily accessible preoperative clinical predictors multivariable models developed predict delayed verbal memory outcome 3 commonly used measures rey auditory verbal learning test ravlt logical memory lm verbal paired associates vpa subtests wechsler memory scalethird edition using harrells stepdown procedure variable selection models developed 359 adults underwent tlr cleveland clinic validated 290 adults 1 5 epilepsy surgery centers united states canada twentynine percent development cohort 26 validation cohort demonstrated significant decline least 1 verbal memory measure initial models goodtoexcellent predictive accuracy calibration c statistic range 7780 identifying patients memory decline however models slightly underestimated decline validation cohort model coefficients updated using data cohorts improve stability model ravlt included surgery side baseline memory score hippocampal resection models lm vpa included surgery side baseline score education updated model performance good excellent ravlt c 81 lm c 76 vpa c 78 model calibration good indicating systematic underestimation risk nomograms provided 2 easytouse formats assist clinicians estimating probability verbal memory decline adults considering tlr treatment epilepsy