Beate-Christin Hope Kolltveit, Bjørg Frøysland Oftedal, Sally Thorne, Kirsten Lomborg, Marit Graue
Experiences of an interprofessional follow-up program in primary care practice
BMC health services research
neonates risk nosocomial tuberculosis tb infection health care workers hcws neonatal care facilities progress severe tb diseases tuberculin skin test tst commonly used tb diagnosis accuracy neonates influenced various factors including bacilli calmettegurin bcg vaccination study aimed identify predictors positive tsts neonates exposed hcws pulmonary tb retrospective observational study conducted compare frequency predictors tstpositive tstnegative neonates demographic epidemiological clinical data neonates exposed tb along hcw household contacts collected retrospectively contact investigations korean national tb surveillance system kntss database tsts using 2 tuberculin units purified protein derivative rt23 performed exposed neonates end preventive tb treatment firth logistic regression performed identify predictors tst positivity contact investigations revealed 152 neonates 54 hcws exposed infectious tb index cases 3 neonatal care facilities 152 exposed neonates 8 53 positive tst results age 6 days initial exposure statistically significant predictor positive tst firth coefficient 21 95 confidence interval 0339 p 0024 bcg vaccination showed statistical significance univariable multivariable analysis sex prematurity exposure duration duration initial exposure contact investigation isoniazid preventive treatment duration significant predictors age initial exposure significant predictor positive tst neonates exposed active pulmonary tb given complexities tst interpretation including false positives due bcg vaccination careful risk assessment necessary appropriate decisionmaking resource allocation management neonatal tb exposure