Gamze Özbek Güven, Şerife Yilmaz, Feyza Inceoğlu
Determining medical students' anxiety and readiness levels about artificial intelligence
Heliyon
human heart electrophysiology complex biological phenomenon indirectly assessed measured ecg signal ecg trace analyzed derive interpretable surrogates including qt interval qrs complex pr interval wave morphology qt interval modification commonly used surrogates drug triggered arrhythmia known qt interval determined nondrug related parameters physiological pathological current study used computational intelligence algorithms analyze correlations various simulated physiological parameters qt interval terfenadine given concomitantly 8 enzymatic inhibitors used example equation developed use genetic programming technique leads general reasoning changes prolonged qt small changes qt interval drugrelated ikr ica currents inhibition potentials major impact physiological parameters body surface area potassium sodium calcium ions concentrations negligible influence physiological variables increases gradually pronounced changes qt significant qt prolongation associated drugs triggered arrhythmia risk analysis role physiological parameters influencing ecg seems advisable