Geza Benke, Michael J Abramson, Chris Brzozek, Steve McDonald, Helen Kelsall, Masoumeh Sanagou, Berihun M Zeleke, Jordy Kaufman, Sue Brennan, Jos Verbeek, Ken Karipidis
The effects of radiofrequency exposure on cognition: A systematic review and meta-analysis of human observational studies
Environment international
article addresses limitations existing statistical models analyzing interpreting highly skewed mirnaseq raw read count data range zero millions heavytailed model using discrete stable distributions proposed novel approach better capture heterogeneity extreme values commonly observed mirnaseq data additionally parameters discrete stable distribution proposed alternative target differential expression analysis r package computing estimating discrete stable distribution provided proposed model applied mirnaseq raw counts norwegian women cancer study nowac cancer genome atlas tcga databases goodnessoffit compared popular poisson negative binomial distributions discrete stable distributions found give better fit datasets conclusion use discrete stable distributions shown potentially lead accurate modeling underlying biological processes