Erin E. Morgan|Steven Paul Woods|Christine Smith|Erica Weber|J. Cobb Scott|Igor Grant
Lower Cognitive Reserve Among Individuals with Syndromic HIV-Associated Neurocognitive Disorders (HAND)
University of California System|University of California System|University of California System|University of Denver|Yale University|University of California System
hivseropositive individuals low cognitive reserve high risk developing hivassociated neurocognitive disorders hand present study evaluated hypothesis cognitive reserve would also play unique role expression everyday functioning complications among hand ie syndromic versus subsyndromic impairment eightysix individuals hiv infection evaluated 53 individuals evidenced normal neurocognitive performance 16 subsyndromic hand ie asymptomatic neurocognitive impairment 17 diagnosed syndromic hand based comprehensive neurobehavioral evaluation cognitive reserve represented combined score including years education estimated verbal iq highest occupational attainment groups comparable eg demographics hand groups similar rates global neurocognitive impairment syndromic hand group evidenced lower reserve scores relative groups suggesting individuals lower reserve may less able effectively counteract neurocognitive impairment maintain independence daily living activities hivinfected individuals high cognitive reserve