Maaike Vandermosten|Jolijn Vanderauwera|Catherine Theys|Astrid De Vos|Sophie Vanvooren|Stefan Sunaert|Johan Wouters|Pol Ghesquière
A DTI tractography study in pre-readers at risk for dyslexia
KU Leuven|KU Leuven|KU Leuven|KU Leuven|KU Leuven|KU Leuven|KU Leuven|KU Leuven
adults schoolaged children phonological aspects reading seem sustained left dorsal regions ventral regions seem involved orthographic word recognition yet given brain reorganises reading acquisition unknown reading routes emerge whether neural deficits dyslexia predate reading onset using diffusion mri 36 prereaders family risk dyslexia frd 35 well matched prereaders without family risk frd results show phonological predictors reading sustained bilaterally ventral dorsal tracts suggests dorsal lefthemispheric specialisation phonological aspects reading observed adults presumably gradually formed throughout reading development second results indicate frd prereaders display mainly white matter differences left ventral tracts suggests atypical white matter organisation previously found dyslexic adults may causal rather resulting lifetime reading difficulties location deficit may vary throughout development study forms important starting point longitudinal followup children allow investigation dynamics emerging literacy development white matter connections