Kavita R Bhatnagar, Aroma Oberoi
Students' perceptions on newly designed foundation course at MBBS entry level: A mixed-method study
Industrial psychiatry journal
ovarian metastases gastrointestinal cancers colorectal cancer also known krukenberg tumors kts present unique challenges management due diagnostic uncertainty decreased responsiveness systemic therapies compared sites metastasis associated debilitating symptomatology thus sought characterize institutional outcomes metastatic colorectal cancer mcrc patients kts retrospective singleinstitution study performed identifying adult female patients 2012 2021 diagnosis mcrc patient demographics clinicopathologic characteristics collected analyzed descriptive statistics univariate multivariable analyses kaplanmeier survival analyses performed 235 mcrc patients 45 191 kts 41 911 kts conjunction metastatic sites initial sites metastasis included liver n 93 396 lung n 28 119 peritoneum n 18 77 kt cohort median age 48 533 nonhispanic white 100 microsatellite stable tumors 333 kristen rat sarcoma virus kras mutations 67 vraf murine sarcoma viral oncogene homolog b braf mutations fifty five point six percent kt patients underwent cytoreductive surgery crs 244 underwent palliative debulking 20 underwent surgical intervention reasons undergoing crs diseaserelated n 14 70 due poor performance status n 1 5 n 5 25 fiveyear overall survival 482 kt patients underwent crs poor tumor grade independent predictor mortality hazard ratio 1069 95 confidence interval 1209547 p 003 almost 90 patient cohort kts mcrc experience additional sites metastasis around half kt patients underwent crs alive 5