Amin Salehi-Abargouei, Afshin Shiranian, Simin Ehsani, Pamela J Surkan, Ahmad Esmaillzadeh
Caesarean delivery is associated with childhood general obesity but not abdominal obesity in Iranian elementary school children
Acta paediatrica (Oslo, Norway : 1992)
transrectal ultrasoundguided prostate biopsy gold standard diagnostic test prostate cancer invasive examination nontargeted puncture high falsenegative rate study aimed develop computerassisted prostate cancer diagnosis method based multiparametric mri mpmri images retrospectively collected 106 patients underwent radical prostatectomy diagnosis prostate biopsy mpmri images including t2 weighted imaging t2wi diffusion weighted imaging dwi dynamiccontrast enhanced dce accordingly analyzed extracted region interest roi tumor benign area three sequential mri axial images level roi data 433 mpmri images obtained 202 benign 231 malignant 50 benign 50 malignant images used training 333 images used verification five main feature groups including histogram glcm glgcm waveletbased multifractional brownian motion features minkowski function features extracted mpmri images selected characteristic parameters analyzed matlab software three analysis methods higher accuracy selected prostate cancer identification based mpmri images found system uses 58 texture features 3 classification algorithms including support vector machine svm knearest neighbor knn ensemble learning el performed well t2wibased classification results svm achieved optimal accuracy auc values 643 067 dcebased classification results svm achieved optimal accuracy auc values 722 077 dwibased classification results ensemble learning achieved optimal accuracy well auc values 751 082 classification results based data combinations svm achieved optimal accuracy auc values 664 073 proposed computeraided diagnosis system provides good assessment diagnosis prostate cancer may reduce burden radiologists improve early diagnosis prostate cancer