Philip Gyaase, Edward Aduse-Poku, Mavis Opoku Lanquaye, Emmanuel Boateng Acheampong, David Ben Sampson
Health seeking behaviour and knowledge on neonatal danger signs among neonatal caregivers in Upper Denkyira East Municipality, Ghana
BMC pediatrics
evidence social interaction inverse association development neurodegenerative diseases predictparkinson disease predictpd online uk cohort study stratifies participants risk future parkinson disease pd study aims explore methodological approach feasibility assessing digital social characteristics people risk developing pd social capital within predictpd platform making hypotheses relationship webbased social engagement potential predictive risk indicators pd webbased application built enable social interaction predictpd portal feedback existing members cohort sought informed design pilot dedicated staff used weekly engagement activities consisting pdrelated research facts queries stimulate discussion data collected hosting platform examined pattern connections generated time cumulative number posts replies ego networks using social network analysis used network metrics describe bonding bridging linking social capital among participants platform relevant demographic data parkinson risk scores expressed odd 1x analyzed using descriptive statistics regression analysis conducted estimate relationship risk scores log transformation network measures overall 219 participants took part 4month pilot forum embedded study website 200 people n80 40 male n113 57 female connected large group pairs users could reach one another either directly indirectly users total 59 2034 discussions spontaneously started participants participation asynchronous individuals acting brokers groups discussions participants joined forum connected one another online posts distinct groups connected users started emerge pilot showed forum application within cohort web platform feasible acceptable fostered digital social interaction matching participants webbased social engagement previously collected data individual level predictpd study feasible showing potential future analyses correlating online network characteristics risk pd time well testing digital social engagement intervention modify risk developing neurodegenerative diseases results pilot suggest online forum serve intervention enhance social connectedness investigate whether patterns online engagement impact risk developing pd longterm followup highlights potential leveraging online platforms study role social capital moderating pd risk underscores feasibility approaches future research interventions