Andrea L. Rosso|Jason D. Flatt|Michelle C. Carlson|Gina S. Lovasi|Caterina Rosano|Arleen F. Brown|Karen A. Matthews|Peter J. Gianaros
Neighborhood Socioeconomic Status and Cognitive Function in Late Life
University of Pittsburgh|University of Pittsburgh|University of Pittsburgh|University of Pittsburgh|University of Pittsburgh|University of Pittsburgh|University of Pittsburgh|University of Pittsburgh
neighborhood socioeconomic status nses associated cognitive function independently individual demographic health socioeconomic characteristics however research largely crosssectional mechanisms association unknown 19921993 cardiovascular health study participants n 3595 mean age 748 years 157 black underwent cognitive testing magnetic resonance imaging white matter hyperintensities wmh addresses geocoded nses calculated using 1990 us census data block groups 6 measures wealth education occupation modified minimental state examination 3ms used assess general cognition digit symbol substitution test dsst used assess speed processing annually 6 years associations racespecific nses tertiles 3ms dsst wmh estimated using linear mixedeffects models accounting geographic clustering stratified race adjusted demographic health individual socioeconomic status education income lifetime occupational status variables fully adjusted models higher nses associated higher 3ms scores blacks mean difference highest lowest nses 24 points p 0004 whites mean difference 07 points p 002 baseline changes 3ms time nses marginally associated dsst associated wmh adjustment wmh attenuate nses3ms associations associations nses cognition late adulthood differ race explained wmh evident baseline