Gillian W. Hooker|Holly Peay|Lori H. Erby|Theodore M. Bayless|Barbara Biesecker|Debra Roter
Genetic Literacy and Patient Perceptions of IBD Testing Utility and Disease Control
National Institutes of Health|National Human Genome Research Institute|National Institutes of Health|National Human Genome Research Institute|Johns Hopkins University|Johns Hopkins Medicine|Johns Hopkins University|National Human Genome Research Institute|National Institutes of Health|Johns Hopkins University
findings inflammatory bowel disease ibd genomewide association studies translated clinically prognostic diagnostic indicators disease yet patient perception understanding tests applicability providing risk information unclear goal study determine using hypothetical scenarios whether patients ibd perceive genetic testing useful risk assessment whether genetic test results impact perceived control whether low genetic literacy may barrier patient understanding teststwo hundred fifty seven patients ibd johns hopkins gastroenterology clinics randomized receive vignette depicting either genetic testing scenario standard blood testing scenario participants asked questions vignette responses compared groupsperceptions test utility risk assessment higher among participants responding genetic vignette p 0001 significant differences perceptions control ibd hypothetical testing vignettes p 024 participant responses modified genetic literacy measured using scale developed study participants randomized genetic vignette scored higher genetic literacy scale perceived greater utility testing risk assessment p 0008 control testing p 002patients ibd perceive utility genetic testing providing information relevant family members appreciation promoted genetic literacy low genetic literacy among patients poses potential threat effective translation genetic genomic tests