Roya Rozati|P.P. Reddy|Pallu Reddanna|Rubina Mujtaba
Role of environmental estrogens in the deterioration of male factor fertility
Tanvir Hospital|Institute of Genetics and Hospital for Genetic Diseases|University of Hyderabad|Tanvir Hospital
evaluate role environmental estrogens polychlorinated biphenyls pcbs phthalate esters pes potential environmental hazards deterioration semen parameters infertile men without obvious etiologyrandomized controlled studytertiary care referral infertility clinic academic research centertwentyone infertile men sperm counts 20 millionml andor rapid progressive motility 25 andor 30 normal forms without evidence obvious etiology 32 control men normal semen analyses evidence conception semen blood samples obtained part treatment protocolevaluation semen parameters ejaculate volume sperm count motility morphology vitality osmoregulatory capacity sperm chromatin stability sperm nuclear dna integritypcbs detected seminal plasma infertile men controls concentration pes significantly higher infertile men compared controls ejaculate volume sperm count progressive motility normal morphology fertilizing capacity significantly lower infertile men compared controls highest average pcb pe concentrations found urban fish eaters followed rural fish eaters urban vegetarians rural vegetarians total motile sperm counts infertile men inversely proportional xenoestrogen concentrations significantly lower respective controlspcbs pes may instrumental deterioration semen quality infertile men without obvious etiology