Martijn J.L. Bours|Bernadette Wilhelmina Antonia van der Linden|Renate M. Winkels|Fränzel J.B. van Duijnhoven|Floortje Mols|Eline H. van Roekel|Ellen Kampman|Sandra Beijer|Matty P. Weijenberg
Candidate Predictors of Health-Related Quality of Life of Colorectal Cancer Survivors: A Systematic Review
Maastricht University|Maastricht University|Wageningen University & Research|Wageningen University & Research|Tilburg University|Netherlands Comprehensive Cancer Organisation|Maastricht University|Wageningen University & Research|Radboud University Nijmegen|Radboud University Medical Center|Netherlands Comprehensive Cancer Organisation|Maastricht University
abstract population colorectal cancer crc survivors growing many survivors experience deteriorated healthrelated quality life hrqol early late posttreatment phases identification crc survivors risk hrqol deterioration improved using prediction models however models currently available oncology practice starting point developing prediction models hrqol crc survivors comprehensive overview potential candidate hrqol predictors necessary therefore systematic literature review conducted identify candidate predictors hrqol crc survivors original research articles associations biopsychosocial factors hrqol crc survivors searched pubmed embase google scholar two independent reviewers assessed eligibility selected articles inclusion n 53 strength evidence candidate hrqol predictors graded according predefined methodological criteria world health organizations international classification functioning disability health icf used develop biopsychosocial framework identified candidate hrqol predictors mapped across main domains icf health condition body structures functions activities participation personal environmental factors developed biopsychosocial icf framework serves basis selecting candidate hrqol predictors thereby providing conceptual guidance developing comprehensive evidencebased prediction models hrqol crc survivors models useful clinical oncology practice aid identifying individual crc survivors risk hrqol deterioration could also provide potential targets biopsychosocial intervention aimed safeguarding hrqol atrisk individuals