Juan Zhang, Yihui Wang, Chantat Leong, Yidi Mao, Zhen Yuan
Bridging Stories and Science: An fNIRS-based hyperscanning investigation into child learning in STEM
NeuroImage
limited data exist regarding child neurodevelopment relation maternal occupational exposure endocrinedisrupting chemicals edcs included 1058 motherchild pairs infancia medio ambiente inma project 20032008 using jobexposure matrix exposure probability scores ten edc groups assigned mother based longest held job pregnancy childs 5year visit mccarthy scales childrens abilities administered yielding general cognitive index scales specific cognitive domains analyzed regionspecific associations edc exposures outcome separately using adjusted linear regression combined regionspecific effect estimates using randomeffects metaanalyses approximately 24 women exposed least one edc group exposure individual edc groups low 5 maternal organic solvent exposure associated lower quantitative scores among children 58 points 95 confidence interval 110 05 though statistically nonsignificant exposures polycyclic aromatic hydrocarbons phthalates alkylphenolic compounds miscellaneous chemicals associated poorer offspring performance cognitive domains study found limited evidence role maternal occupational edc exposures child cognition research needed better characterize exposures among pregnant workers using data prospective birth cohort help fill important research gap regarding potential consequences workrelated exposure endocrinedisrupting chemicals edcs among pregnant women child neurodevelopment expand existing literaturelargely limited pesticide organic solvent exposuresby using jobexposure matrix estimate exposure several edc groups found limited evidence association maternal occupational edc exposure childrens overall cognition observe specific associations exposure organic solvents lower quantitative reasoning scores