Patricia A. Marshall|Clement Adebamowo|Adebowale Adeyemo|Temidayo O. Ogundiran|Mirjana Vekich|Teri Strenski|Jie Zhou|T. Elaine Prewitt|Richard Cooper|Charles N. Rotimi
Voluntary Participation and Informed Consent to International Genetic Research
Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University|Howard University|Case Western Reserve University
objectives compared voluntary participation comprehension informed consent among individuals african ancestry enrolled similarly designed genetic studies hypertension united states nigeria methods survey questionnaires used evaluate factors associated voluntariness number people volunteering understanding studys genetic purpose total 655 individuals united states 348 nigeria 307 interviewed participation genetic studies results us respondents 99 compared 72 nigerian respondents reported told study purpose fewer half respondents sites reported study purpose learn genetic inheritance hypertension respondents indicated participation voluntary united states 97 reported could withdraw compared 67 nigeria nigeria nearly half married women reported asking permission husbands enroll hypertension study respondents sought permission local elders participate study conclusions findings highlight need effective approaches interventions improve comprehension consent genetic research among ethnically linguistically diverse populations settings