Tingyan Dong, Yueming Liang, Junting Xie, Wentao Fan, Haitao Chen, Xiaodong Han
Integrative analyses identify opportunistic pathogens of patients with lower respiratory tract infections based on metagenomic next-generation sequencing
Heliyon
exposure ambient fine particles particulate matter aerodynamic diameter 25 pm25 public health concern concentrations ambient pm25 changed temporally past 10 years series action policies improving air quality implemented taiwan study temporal changes relationship pm25 lung function among children investigated nationwide respiratory health survey conducted among taiwanese elementary middle school students 2011 20162017 questionnaire administered students forced vital capacity fvc forced expiratory volume 1 fev1 measured using spirometry study period monthly concentrations ambient pm25 obtained monitoring stations environmental protection administration lung function measurements compared ambient pm25 exposure using mixedeffects models 2011 survey mean pm25 406 gm3 exposure pm25 preceding 12 months associated 22 decrease 95 confidence interval ci 41 03 fvc 23 decrease 95 ci 40 05 fev1 contrast significant relationship pm25 concentrations lung function observed 20162017 survey mean pm25 300 gm3 improvement air quality time negative relationship pm25 childhood lung function tend significant