Rajendra H. Mehta|J.Conor O’Shea|Amanda Stebbins|Christopher B. Granger|Paul W. Armstrong|Harvey D. White|Eric J. Topol|Robert M. Califf|E. Magnus Ohman
Association of Mortality With Years of Education in Patients With ST-Segment Elevation Myocardial Infarction Treated With Fibrinolysis
Duke Medical Center|Clinical Research Institute|Bon Secours Hospital Cork|Duke Medical Center|Clinical Research Institute|Duke Medical Center|Clinical Research Institute|University of Alberta|Auckland City Hospital|Scripps Clinic|Duke Medical Center|Clinical Research Institute|Duke Medical Center|Clinical Research Institute
purpose study examine association lower socioeconomic status ses ascertained years education outcomes patients acute stsegment elevation myocardial infarction stemi previous studies shown inverse relationship ses coronary heart disease mortality whether similar association ses mortality exists stemi patients unknown evaluated 11326 patients stemi gustoiii global use strategies open occluded coronary arteries trial study countries enrolled 500 patients evaluated clinical outcomes adjusted using multivariate regression analysis according number years education completed oneyear mortality inversely related years education 5fold higher patients 8 years compared 16 years education 175 vs 35 p 00001 strength relationship education mortality varied among different countries nonetheless years education remained independent correlate mortality day 7 hazard ratio per year increase education 086 95 confidence interval 083 088 also day 8 1 year hazard ratio per year increase education 096 95 confidence interval 094 098 even adjustment baseline characteristics country enrollment number years education used measure ses inverse relationship significantly higher shortterm 1year mortality existed beyond accounted baseline clinical variables country enrollment future studies account investigate mechanisms underlying link ses cardiovascular disease outcomes