Samuel G Smith, Michael S Wolf, Christian von Wagner
Socioeconomic status, statistical confidence, and patient-provider communication: an analysis of the Health Information National Trends Survey (HINTS 2007)
Journal of health communication
expected increase dementia prevalence coming decades mainly lowincome middleincome countries people low socioeconomic status highincome countries study aims reduce dementia risk factors underserved populations highrisk using coachsupported mobile health mhealth intervention openlabel blinded endpoint hybrid effectivenessimplementation randomised controlled trial rct investigated whether coachsupported mhealth intervention reduce dementia risk people aged 5575 years low socioeconomic status uk general population china least two dementia risk factors primary effectiveness outcome change cardiovascular risk factors ageing incidence dementia caide risk score baseline 1218 months intervention implementation outcomes coverage adoption sustainability appropriateness acceptability fidelity feasibility costs assessed using mixedmethods approach participants complete data primary outcome without imputation missing outcomes included analysis intentiontotreat principle trial registered isrctn isrctn15986016 completed jan 15 2021 april 18 2023 1488 people 601 male 887 female randomly assigned 734 intervention 754 control 1229 83 1488 available analysis primary effectiveness outcome mean followup 16 months sd 25 mean caide score improved 016 points intervention group versus 001 control group mean difference 016 95 ci 029 003 1533 10 invited individuals responded intervention participants 593 81 734 adopted intervention 367 50 734 continued active participation throughout study perceived appropriateness 85 acceptability 81 fidelity 79 good fair overall feasibility 53 intervention participants 58 coaches low cost differences adverse events study arms found coachsupported mhealth intervention modestly effective reducing dementia risk factors low socioeconomic status uk socioeconomic status china implementation challenging populations reached actively participated whether intervention result less cognitive decline dementia requires larger rct long followup eu horizon 2020 research innovation programme national key rd programmes china mandarin translation abstract see supplementary materials section