Traci C. Green|Ryan A. Black|Jill M. Grimes Serrano|Simon H. Budman|Stephen F. Butler
Typologies of Prescription Opioid Use in a Large Sample of Adults Assessed for Substance Abuse Treatment
Brown University|Providence College|Rhode Island Hospital|Inflexxion (United States)|Inflexxion (United States)|Inflexxion (United States)|Inflexxion (United States)
population nonmedical prescription opioid users welldefined aimed derive describe typologies prescription opioid use nonmedical use using latent class analysis adult population assessed substance abuse treatmentlatent class analysis applied data 26314 unique respondents aged 1870 selfreporting past month use prescription opioid total 138928 cases 189 collected addiction severity indexmultimedia version asimv national database near realtime prescription opioid abuse surveillance data obtained november 2005 december 2009 substance abuse treatment criminal justice public assistance programs united states submitted data asimv database n 538 six indicators latent classes derived responses asimv version asi modified collect prescription opioid abuse chronic pain experience latent class analysis included respondent home zip code random effects account nesting respondents within zip codea fourclass adjusted latent class model fit best defined clinically interpretable relevant subgroups use prescribed prescribed misusers medically healthy abusers illicit users classes varied key variables including raceethnicity gender concurrent substance abuse duration prescription opioid abuse mental health problems asi composite scores three four classes 81 respondents exhibited high potential risk fatal opioid overdose 184 exhibited risk factors bloodborne infectionsmultiple distinct profiles prescription opioid use detected suggesting range use typologies differing risk adverse events results may help clinicians policy makers better focus overdose bloodborne infection prevention efforts intervention strategies prescription opioid abuse reduction