Trinh L T Huynh, Whitney N Neal, Elizabeth A Barstow, Robert W Motl
Physical Activity in Individuals Newly Diagnosed With Multiple Sclerosis Through the Lens of the COM-B Model
International journal of MS care
multiparametric magnetic resonance imaging mpmri diagnostic tool used screening localizing staging prostate cancer patients prostate imaging reporting data system pirads score 1 2 considered negative mpmri lower likelihood detecting clinically significant prostate cancer cspca however relying solely mpmri insufficient completely exclude cspca necessitating stratification cspca patients using biomarkers retrospective study conducted mpmrinegative patients underwent prostate biopsy first affiliated hospital zhejiang university january 2022 june 2023 total 607 patients included based inclusion exclusion criteria univariate multivariate logistic regression analysis performed identify risk factors diagnosing cspca patients negative mpmri receiver operating characteristic roc curves plotted compare discriminatory ability different prostatespecific antigen density psad cutoff values cspca among 607 patients negative mpmri 73 patients diagnosed cspca univariate logistic regression analysis age psa ftpsa prostate volume psad associated diagnosing cspca patients negative mpmri p 005 psad accurate predictor multivariate logistic regression analysis ftpsa age psad independent predictors cspca p 005 psad cutoff value 020 ngmlml better discriminatory ability predicting cspca significant risk factor cspca multivariate analysis age ftpsa psad independent predictors diagnosing cspca patients negative mpmri suggested patients negative mpmri psad less 020 ngmlml could avoid prostate biopsy psad cutoff value 020 ngmlml better diagnostic performance traditional cutoff value 015 ngmlml