Esther Yoon, Scott Hur, Laura M Curtis, Julia Yoshino Benavente, Michael S Wolf, Marina Serper
Patient factors associated with telehealth quality and experience among adults with chronic conditions
JAMIA open
increased access research laboratories isolated human islets improved understanding biology endocrine pancreas hence mechanisms causing diabetes however vitro studies human islets remain technically challenging optimal use precious material requires minimum rigor coordination optimize reliability share information detailed report demographics pancreas donors procedures islet handling isolation important insufficient correct characterization islet basic functions token quality time experimentation also crucial analyzed literature reporting measurements insulin glucagon human pancreas isolated human islets published information often fragmentary elementary features islet size insulin content rate hormone secretion either unreported incorrectly reported many papers although internal comparisons control test groups may remain valid comparisons data laboratories problematic drawbacks pitfalls errors common ways expressing hormone content secretion rates discussed alternatives harmonize data presentation proposed greater coherence rigor report vitro studies using human islets necessary ensure optimal progress understanding pathogenesis diabetes