Matheus Lotto|Olívia Santana Jorge|Tamires Sá Menezes|Ana Maria Ramalho|Thaís Marchini de Oliveira|Fernando Bevilacqua|Thiago Cruvinel
Psychophysiological Reactions of Internet Users Exposed to Fluoride Information and Disinformation: Protocol for a Randomized Controlled Trial
Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade Federal da Fronteira Sul|Universidade de São Paulo
false messages internet continually propagate possible adverse effects fluoridated oral care products water despite essential role preventing controlling dental cariesthis study aims evaluate patterns psychophysiological reactions adults consumption internetbased fluoriderelated information disinformationa 2armed singleblinded parallel randomized controlled trial conducted 58 parents caregivers children attend clinics pediatric dentistry bauru school dentistry considering attrition 10 significance level 5 participants randomized test intervention groups respectively exposed fluoriderelated information disinformation presented computer simultaneous monitoring psychophysiological reactions including analysis heart rates hrs 7 facial features mouth outer mouth corner eye area eyebrow activity face area face motion facial center mass participants respond questions utility truthfulness content emotional state experiment ehealth literacy oral health knowledge socioeconomic characteristics shapirowilk levene tests used determine normality homogeneity data could lead statistical analyses elucidating significant differences groups using parametric student test nonparametric mannwhitney u test analyses moreover multiple logistic regression models developed evaluate association distinct variables psychophysiological aspects factors significant wald statistics simple analysis included multiple models p2 furthermore receiver operating characteristic curve analysis performed determine accuracy remote hr respect measured hr analyses p05 considered significantfrom june 2022 parents caregivers frequent clinics pediatric dentistry bauru school dentistry invited participate study randomized 1 2 groups control intervention data collection expected completed december 2023 subsequently authors analyze data publish findings clinical trial june 2024this randomized controlled trial aims elucidate differences psychophysiological patterns adults exposed true false oral health content evidence may support development studies digital strategies neural network models automatically detect disinformation available internetbrazilian clinical trials registry rbr7q4ymr2 u111112638227 httpstinyurlcom2kf73t3dprr110219639133