Karen Bell, Syed Ghulam Sarwar Shah, Lorna R Henderson, Vasiliki Kiparoglou
Translational researchers' training and development needs, preferences, and barriers: A survey in a National Institute for Health Research Biomedical Research Centre in the United Kingdom
Clinical and translational science
oxidative coupling methane ocm promising process converting natural gas highvalue chemicals ethane ethylene process however requires important improvements commercialization foremost increasing process selectivity c2 c2h4 c2h6 moderate high levels methane conversion developments often addressed catalyst level however optimization process conditions lead important improvements study highthroughput screening hts instrument utilized la2o3ceo2 33 mol ce generate parametric data set within temperature range 600800 c ch4o2 ratio 3 13 pressure 1 10 bar catalyst loading 5 20 mg leading spacetime 40 172 statistical design experiments doe applied gain insights effect operating parameters determine optimal operating conditions maximum production ethane ethylene rateofproduction analysis used shed light elementary reactions involved different operating conditions data obtained hts experiments established quadratic equations relating studied process variables output responses quadratic equations used predict optimize ocm process results demonstrated ch4o2 ratio operating temperatures key controlling process performance operating higher temperatures high ch4o2 ratios increased selectivity c2 minimized cox co co2 moderate conversion levels addition process optimization doe results also allowed flexibility manipulating performance ocm reaction products c2 selectivity 61 methane conversion 18 found optimum 800 c ch4o2 ratio 7 pressure 1 bar