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increasing accessibility commercial private space travel necessitates profound understanding impact human health nasa open science data repository osdr provides transparent fair access biological studies notably spacex inspiration4 i4 mission amassed extensive data civilian astronauts dataset encompasses omics clinical assays facilitating comprehensive research spaceinduced biological responses data allow multimodal longitudinal assessments bridging gap human model organism studies crucially communitydriven data standards established nasas osdr analysis working groups empower artificial intelligence machine learning glean invaluable insights guiding future mission planning health risk mitigation article presents concise guide access analyze i4 data osdr including programmatic access glopenapi pioneering effort establishes precedent postmission health monitoring programs within space agencies propelling research burgeoning field commercial space travels impact human physiology