Corina U. Greven|Yulia Kovas|Erik G. Willcutt|Stephen A. Petrill|Robert Plomin
Evidence for shared genetic risk between ADHD symptoms and reduced mathematics ability: a twin study
Radboud University Nijmegen|Radboud University Medical Center|King's College London|King's College London|National Research Tomsk State University|Goldsmiths University of London|University of Colorado Boulder|The Ohio State University|King's College London
attentiondeficithyperactivity disorder adhd symptoms mathematics ability associated little known genetic environmental influences underlying associationdata came 6000 twelveyearold twin pairs uk populationrepresentative twins early development study parents rated twins behaviour using dsmivbased 18item questionnaire inattentive hyperactiveimpulsive adhd symptoms mathematics tests based uk national curriculum completed twin twins also completed standardised tests reading general cognitive ability multivariate twin model fitting appliedinattentive hyperactiveimpulsive adhd symptoms highly heritable 67 73 respectively mathematics ability moderately heritable 46 mathematics ability inattentiveness showed significantly greater phenotypic correlation rp 26 genetic correlation ra 41 mathematics ability hyperactivityimpulsivity rp 18 ra 22 genetic correlation inattentiveness mathematics ability largely independent hyperactivityimpulsivity partially accounted genetic influences related reading general cognitive abilityresults revealed novel finding mathematics ability shows significantly stronger phenotypic genetic associations inattentiveness hyperactivityimpulsivity genetic associations inattentiveness mathematics ability could partially accounted hyperactivityimpulsivity reading general cognitive ability results suggest mathematics ability associated adhd symptoms largely shares genetic risk factors inattentiveness provide evidence considering inattentiveness hyperactivityimpulsivity separately dna markers adhd symptoms especially inattentiveness may also candidate risk factors mathematics ability vice versa