Denise Vagnini, Nicolò Lamperti, Sara Molgora, Francesca Barile, Federica Facchin, Umberto Mazza, Emanuela Saita
Mental Health Issues as a Consequence of the Pandemic: Group Psycho-Educational Intervention to Support Patients Recovered from COVID-19 Infection
International journal of environmental research and public health
plasma levels markers coagulation inflammation identified prognostic factors adult postthrombotic syndrome pts aimed determine whether plasma fibrinolytic capacity cytokine levels first 3 months provoked deep venous thrombosis dvt associated risk pts young patients analyzed plasma biospecimens 6 weeks 3 months provoked dvt clinical data national heart lung blood institutesponsored multinational trial anticoagulation provoked venous thromboembolism patients younger age 21 years kidsdott patients provoked extremity dvt plasma samples available 6week 3month postdvt time points pts assessment 1 year included measured plasma fibrinolytic capacity using clot formation lysis clofal assay plasma cytokine levels multiplex immunoassay logistic regression analyses evaluated prognostic associations pts seventynine patients included median age 128 years range 004208 years pts developed 34 complete venoocclusion 6 weeks diagnosis dvt odds ratio 312 95 confidence interval ci 0811194 p 097 low fibrinolytic capacity plasma 3 months postdvt 271 95 ci 092797 p 07 elevated serum amyloid 3 months postdvt 285 95 ci 098834 p 055 identified putative prognostic factors development pts multivariable logistic regression analysis factors retain statistically significant independent association pts preliminary results warrant investigation independent data set definitively evaluate findings identify additional potential prognostic factors development pts provoked dvt young patients