L Tan, L Cheng, W Yan, J Zhang, B Xu, V K Diwan, H Dong, L Palm, Y Wu, L Long, Y Tian, S Nie
Using daily syndrome-specific absence data for early detection of school outbreaks: a pilot study in rural China
Public health
weather changes among proposed precursors painful sickle cell crises however epidemiologic data mixed regarding relationship ambient temperature crisis frequency study relationship among local sickle cell disease population emergency department ed visits admissions evaluated adults sickle cell crisis primary diagnosis major teaching hospital temperate climate official daily ambient temperatures average day obtained national climate data center days patients visited ed hospitalized 24 48 hours prior daily ed visit counts admission counts correlated visitadmission days ambient temperature ambient temperature 24 hours admission magnitude change daily ambient temperature prior 24 48 hours correlations statistical significance defined p value 001 clinical significance defined moderate greater correlation absolute value r 030 ed visits admissions correlated statistically clinically daily temperatures days temperatures 32 degrees f 80 degrees f correlations statistically significant clinical significance variable ed visits admissions correlated statistically temperatures 24 hours prior even days temperatures 32 degrees f temperatures 80 degrees f correlations statistically significant reverse clinically significant correlation admissions temperatures finally statistically significant correlations found ed visits admissions change temperature prior 24 48 hours weak inconsistent confirmation relationship found daily ambient temperatures ed visits hospital admissions sickle cell crises