Ahmad Mobin, Cindy Xin Feng, Cory Neudorf
Cybervictimization among preadolescents in a community-based sample in Canada: Prevalence and predictors
Canadian journal of public health = Revue canadienne de sante publique
aimed investigate whether type sleep disturbances ie prbd eds insomnia specifically associated faster decline global cognition different cognitive domains among de novo pd patients also assessed influence sleep disturbances core ad csf biomarkers alterations conversion dementia prospectively longitudinal data obtained ppmi cohort sleep disturbances cognition ability assessed questionnaires baseline followup visits generalized linear mixed models utilized assess effect sleep disturbances cognitive decline core ad csf biomarkers change associations sleep disturbances conversion dementia analyzed using cox regression analysis baseline prbd associated faster decline global cognition cognitive domains including verbal episodic memory visuospatial ability executive function language processing speed eds associated faster decline three cognitive domains including verbal episodic memory executive functionworking memory processing speed insomnia associated faster decline global cognition verbal episodic memory meanwhile prbd eds associated longitudinal decrease csf a42 baseline prbd increased risk conversion dementia risk dementia pd patients multiple sleep disturbances also increased compared without sleep disturbance sleep disturbances ie prbd eds insomnia associated cognitive decline early pd eds prbd associated decrease csf a42 moreover prbd associated conversion dementia