Anas Bilal, Abdulkareem Alzahrani, Abdullah Almuhaimeed, Ali Haider Khan, Zohaib Ahmad, Haixia Long
Advanced CKD detection through optimized metaheuristic modeling in healthcare informatics
Scientific reports
uncertainty relative benefits harms hyperthermic intraoperative peritoneal chemotherapy hipec added cytoreductive surgery crs systemic chemotherapy systemic chemotherapy alone people peritoneal metastases colorectal gastric ovarian cancers searched randomized controlled trials rcts medical literature april 14 2022 applied methods used highquality systematic reviews included total eight rcts seven rcts included quantitative analysis one rct provide data analyzable format comparisons ovarian cancer contained one trial gastric cancer high uncertainty effect crs hipec systemic chemotherapy stage iii greater epithelial ovarian cancer undergoing interval cytoreductive surgery crs hipec systemic chemotherapy probably decreases allcause mortality compared crs systemic chemotherapy colorectal cancer crs hipec systemic chemotherapy probably results little difference allcause mortality may increase serious adverse events proportions compared crs systemic chemotherapy probably decreases allcause mortality compared fluorouracilbased systemic chemotherapy alone role crs hipec gastric peritoneal metastases uncertain crs hipec standard care women stage iii greater epithelial ovarian cancer undergoing interval crs crs systemic chemotherapy standard care people colorectal peritoneal metastases hipec given part rct focusing subgroups regimes crd42019130504