Xiaoning Lei, Yan Zhang, Zixia Wang, Zhenping Lu, Chengyu Pan, Shanyu Zhang, Qian Chen, Tao Yuan, Jun Zhang, Yu Gao, Ying Tian
Effects of prenatal exposure to PM2.5 and its composition on cognitive and motor functions in children at 12 months of age: The Shanghai Birth Cohort Study
Environment international
lower socioeconomic status measured index multiple deprivation imd associated higher rates smokingrelated disease mortality poor uptake cancer screening explore whether socioeconomic status impacts effectiveness single round lowdosect screening impacts causes death ukls ldct screening trial imd quintiles defined according ukwide data deprived group defined lower two quintiles q12 less deprived q35 followup data obtained lung cancer diagnosis median followup 91 years cause death median followup 99 years outcomes compared based imd group trial arm ct control deprived quintiles less likely respond questionnaire population likely selected screening llp risk model lower imd quintiles benefitted lowdosect screening terms lung cancer survival hr 189 95 ci 116308 extent upper quintiles hr 187 95 ci 107326 however bigger impact deaths due copd emphysema deprived quintiles whilst ldct screening benefit lung cancer similar significant impact rates death smokingrelated diseases notably copd emphysema seen primarily lower socioeconomic groups future research required confirm lung cancer screening benefits disease outcomes nihr health technology assessment programme nihr policy research programme roy castle lung cancer foundation