Kathryn E. Mansfield|Rohini Mathur|John Tazare|Alasdair D Henderson|Amy Mulick|Helena Carreira|Anthony Matthews|Patrick Bidulka|Alicia Gayle|Harriet Forbes|Sarah Cook|Angel Wong|Helen Strongman|Kevin Wing|Charlotte Warren?Gash|Sharon L Cadogan|Liam Smeeth|Joseph Hayes|Jennifer Quint|Martin McKee|Sinéad Langan
Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study
London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|Karolinska Institutet|London School of Hygiene & Tropical Medicine|Imperial College London|London School of Hygiene & Tropical Medicine|University of Bristol|London School of Hygiene & Tropical Medicine|UiT The Arctic University of Norway|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|University College London|Imperial College London|London School of Hygiene & Tropical Medicine|London School of Hygiene & Tropical Medicine|Health Data Research UK
concerns response covid19 pandemic uk might worsened physical mental health reduced use health services however scale problem unquantified impeding development effective mitigations aimed ascertain happened general practice contacts acute physical mental health outcomes pandemicusing deidentified electronic health records clinical research practice datalink cprd aurum covering 13 uk population 2017 2020 calculated weekly primary care contacts selected acute physical mental health conditions anxiety depression selfharm fatal nonfatal severe mental illness eating disorder obsessivecompulsive disorder acute alcoholrelated events asthma exacerbation chronic obstructive pulmonary disease exacerbation acute cardiovascular events cerebrovascular accident heart failure myocardial infarction transient ischaemic attacks unstable angina venous thromboembolism diabetic emergency primary care contacts included remote facetoface consultations diagnoses hospital discharge letters secondary care referrals conditions identified primary care records diagnoses symptoms prescribing overall study population included individuals aged 11 years older least 1 year registration practices contributing cprd aurum specified period denominator populations varied depending condition analysed used interrupted timeseries analysis formally quantify changes conditions introduction populationwide restrictions defined march 29 2020 compared period introduction defined jan 1 2017 march 7 2020 data excluded adjustmenttorestrictions period march 828the overall population included 9 863 903 individuals jan 1 2017 increased 10 226 939 jan 1 2020 primary care contacts almost conditions dropped considerably introduction populationwide restrictions largest reductions observed contacts diabetic emergencies odds ratio 035 95 ci 025050 depression 053 052053 selfharm 056 054058 interrupted timeseries analysis exception acute alcoholrelated events 098 089110 evidence reduction contacts conditions anxiety 067 066067 eating disorders 062 059066 obsessivecompulsive disorder 069 064074 selfharm 056 054058 severe mental illness 080 078083 stroke 059 056062 transient ischaemic attack 063 058067 heart failure 062 060064 myocardial infarction 072 068077 unstable angina 072 060087 venous thromboembolism 094 090099 asthma exacerbation 088 086090 july 2020 except unstable angina acute alcoholrelated events contacts conditions recovered prelockdown levelsthere substantial reductions primary care contacts acute physical mental conditions following introduction restrictions limited recovery july 2020 research needed ascertain whether reductions reflect changes disease frequency missed opportunities care maintaining healthcare access key priority future public health planning including restrictions conditions studied sufficiently severe unmet need substantial ramifications people conditions well healthcare provisionwellcome trust senior fellowship health data research uk