Colleen M. McBride|Sharon Hensley Alford|Robert J. Reid|Eric B. Larson|Andreas D. Baxevanis|Lawrence C. Brody
Putting science over supposition in the arena of personalized genomics
National Human Genome Research Institute|National Institutes of Health|Henry Ford Hospital|Group Health Cooperative|Group Health Cooperative|National Human Genome Research Institute|National Institutes of Health|National Human Genome Research Institute|National Institutes of Health
colleen mcbride colleagues argue progress multifaceted research agenda necessary reap full benefits avoid potential pitfalls emerging area personalized genomics also outline one element agenda multiplex initiative underway since 2006 explore process going genome discovery evaluation medical impact discuss emerging challenges faced scientific community need confront challenges heightened climate unregulated genetic tests marketed directly general public12 specifically characterize delicate balance involved deciding genomic discoveries genedisease associations ready evaluated potential tools improve health recommend considerable research commitment made order successfully bridge rapidly widening gap genedisease association research critical slower involved investigations public health clinical utility lastly describe large ongoing earlyphase research project multiplex initiative examining issues related utility genetic susceptibility testing common health conditions