Alexandre Vallée
Challenges and directions for digital twin implementation in otorhinolaryngology
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
objective identify modifiable prognostic factors high societal costs among people sick leave due musculoskeletal disorders identify modifiable prognostic factors high costs related separately healthcare utilisation productivity loss prospective cohort study 1year followup total 549 participants aged 1867 years sick leave 4 weeks due musculoskeletal disorders norway included primary outcome societal costs aggregated 1 year followup dichotomised high low defined top 25th percentile secondary outcomes high costs related separately healthcare utilisation productivity loss aggregated 1 year followup healthcare utilisation collected public records included primary secondary tertiary healthcare use productivity loss collected public records included absenteeism work assessment allowance disability pension nine modifiable prognostic factors selected based previous literature univariable multivariable binary logistic regression analyses performed identify associations crude adjusted selected covariates modifiable prognostic factor high costs adjusted selected covariates six modifiable prognostic factors associated high societal costs identified pain severity disability selfperceived health sleep quality return work expectation longlasting disorder expectation depressive symptoms work satisfaction health literacy showed prognostic value less similar results observed high costs related separately healthcare utilisation productivity loss factors identified study potential target areas interventions could reduce high societal costs among people sick leave due musculoskeletal disorders however future research aimed replicating findings warranted nct04196634 12 december 2019