Geohana Hamoy-Jimenez|Woojin Kim|Suganth Suppiah|Gelareh Zadeh|Vera Bril|Carolina Barnett
Quality of life in patients with neurofibromatosis type 1 and 2 in Canada
University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|University Health Network|University of Toronto|Public Health Ontario|University Health Network|University of Toronto
scarce data quality life people neurofibromatosis type 1 nf1 type 2 nf2 canadaa crosssectional study adults nf1 nf2 attending tertiary center patients completed generic measures sf36 eq5d5l promis pain interference diseasespecific questionnaires pedsql nf1 module nftiqol nf2 compared generic scores nf1 nf2 individuals used regression models assess factors associated quality lifehundred eightyfour participants enrolled mean age 33 years nf1 40 years nf2 nf1 nf2 individuals lower employment rates lower scores domains sf36 compared general canadian population p 005 using eq5d5l high proportion pain 64 nf1 74 nf2 anxietydepression 60 nf1 68 nf2 pain interference correlated poor quality life nf1 nf2 perceived physical appearance main predictor mental wellbeing nf1individuals nf1 nf2 low quality life correlates pain anxiety depression prevalent nf1 nf2 perceived physical appearance predicts quality life nf1 multidisciplinary approach necessary patients nf1 nf2 including mental health pain management