Abebaw Tiruneh, Daniel Kahase, Endalew Zemene, Eyob Tekalign, Absra Solomon, Zeleke Mekonnen
Identification of transmission foci of Schistosoma mansoni: narrowing the intervention target from district to transmission focus in Ethiopia
BMC public health
evaluate national trends pediatric severe sepsis united states 2003 2014 study included nonoverlapping years kids inpatient database national inpatient sample database including hospitalizations children 1 20 years age 4200 hospitals across united states identified patient hospitalizations severe sepsis using specific icd codes modified angus criteria trend analysis various factors associated severe sepsis calculated using cochranearmitage test associated foci infection comorbid conditions identified using specific icd codes multivariate regression analysis death outcome variable done evaluate hospital predictors mortality totally 109026 episodes severe sepsis identified study period 2003 2014 incidence severe sepsis hospitalizations increased 25 times 064157 per 10000 population study period notable concurrent significant decrease mortality 50 lower age african american hispanic ethnicity complex neurologic conditions infective endocarditis immunodeficient states including primary immunodeficiency disorder hiv burns malignancy transplant status associated mortality significant increase use healthcare resources p 0001 mean charges 94966 despite notable decrease mean length stay 22 vs 16 days p 0001 study period incidence pediatric severe sepsis high leading significant use healthcare resources study provides detailed analysis associated inpatient factors comorbidities associated mortality