Cong Khanh Nguyen, My Linh Thi Nguyen, Ha Thi Tran, Tam An Nu Nguyen
Development and preliminary evaluation of the interpersonal problem-solving inventory for elementary school students
The British journal of educational psychology
prognostication outcome severe stroke patients necessitating invasive mechanical ventilation poses significant challenges objective study assess prognostic significance prevalence early electroencephalogram eeg abnormalities adult stroke patients receiving mechanical ventilation study preplanned ancillary investigation within prospective multicenter spice cohort study 20172019 conducted 33 intensive care units icus paris area france included adult stroke patients requiring invasive mechanical ventilation underwent least one intermittent eeg examination icu stay primary endpoint functional neurological outcome one year determined using modified rankin scale mrs dichotomized unfavorable mrs 46 indicating severe disability death favorable mrs 03 multivariable regression analyses employed identify eeg abnormalities associated functional outcomes 364 patients enrolled spice study 153 patients 49 ischemic strokes 52 intracranial hemorrhages 52 subarachnoid hemorrhages underwent least one eeg median time 4 interquartile range 27 days poststroke rates diffuse slowing 70 vs 63 p 037 focal slowing 38 vs 32 p 015 periodic discharges 23 vs 37 p 09 electrographic seizures 45 vs 37 p 04 comparable patients unfavorable favorable outcomes following adjustment potential confounders unreactive eeg background auditory pain stimulations 602 95 ci 2271599 independently associated unfavorable outcomes unreactive eeg predicted unfavorable outcome specificity 48 95 ci 4056 sensitivity 79 95 ci 7285 positive predictive value ppv 74 95 ci 6781 conversely benign eeg defined continuous reactive background activity without seizure periodic discharges triphasic waves burst suppression predicted favorable outcome specificity 89 95 ci 8494 sensitivity 37 95 ci 3045 absence eeg reactivity independently predicts unfavorable outcomes one year severe stroke patients requiring mechanical ventilation icu although prognostic value remains limited conversely benign eeg pattern associated favorable outcome