Martin Schmidt, Brian Pinney, Craig Canby, April Vargus, Marianka Pille
An early-curricular team learning activity to foster integration of biochemical concepts and clinical sciences in undergraduate medical education
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
human papillomavirus hpv prevalent sexually transmitted infection globally key risk factor highgrade cervical lesions cervical cancer since 2009 hpv vaccination part national immunization program girls 7th grade norway women born 1997 later study aimed assess impact hpv vaccination incidence highgrade cervical precursors cin2 among women aged 2025 troms finnmark 15year period time series study analyzed cervical screening data 15328 women aged 2025 troms finnmark collected 2008 2022 statistical methods including linear logistic regression employed evaluate changes cervical intraepithelial neoplasia grade 2 worse cin2 incidence compare risks vaccineoffered cohorts prevaccine cohorts incidence cin2 initially increased 31 cases per year 2008 110 cases 2018 significantly decreased 44 cases per year 2022 p 001 women prevaccine cohorts substantially higher risk cin2 902 95 ci 59138 cin3 196 95 ci 73526 notably vaccinated women cin2 tested positive hpv types 16 18 furthermore none 13 cervical cancer cases recorded study vaccinated cohorts findings suggest significant reduction incidence highgrade cervical precursors following introduction hpv vaccine norways national immunization program highlighting effectiveness cervical cancer prevention among young women northern norway