Ashleigh B Johnson, Chelsea M Montgomery, Wesley A Dillard, Kenneth Morrill, Coral Hoesli, Wesley M Gillette, Brandon K Johnson, Thomas I Nathaniel
Effect of Visual Art School-Based Stroke Intervention for Middle School Students
The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
investigate relation patient characteristics rheumatoid arthritis ra diagnosis subsequent initiation treatment biologic diseasemodifying antirheumatic drugs bdmards targeted synthetic dmards tsdmards retrospective cohort study consecutive patients n330 early ra symptom duration 12 months diagnosed skne university hospital malmlund sweden 2012 2016 included data demographics education comorbidities treatment obtained national registers relation patient characteristics diagnosis time first bdmardtsdmard initiation analysed using cox regression models secondary outcome relation characteristics diagnosis btsdmard initiation within 3 years analysed using logistic regression total 330 patients mean age 592 years sd 164 included followup 41 received bdmard never preceded tsdmard higher age diagnosis associated lower probability starting bdmard treatment multivariableadjusted hr 066 per sd 95 ci 056 078 anticitrullinated protein antibody acpa positivity higher tender joint count diagnosis also associated subsequent bdmard treatment initiation multivariable analysis higher level formal education absence comorbidities predicted start bdmard crude ageadjusted analyses older patients ra less likely start bdmards whereas acpapositive patients extensive joint involvement diagnosis likely receive early bdmard treatment impact age subsequent start bdmard therapy explained level education comorbidities suggesting aspects age influence treatment decisions early ra