John Browne|Ranjeet Jeevan|Carmel Gulliver?Clarke|Jerome Pereira|Christopher M. Caddy|Jan van der Meulen
The association between complications and quality of life after mastectomy and breast reconstruction for breast cancer
University College Cork|Royal College of Surgeons of England|University Hospitals Sussex NHS Foundation Trust|National Health Service|National Health Service|James Paget University Hospital|Sheffield Teaching Hospitals NHS Foundation Trust|National Health Service|Faculty of Public Health|London School of Hygiene & Tropical Medicine
medical treatment breast cancer associated substantial toxicity patient burden less known impact surgical complications understanding impact could provide important information patients considering surgical optionsbetween 2008 2009 uk national mastectomy breast reconstruction audit recorded surgical complications prospective cohort 17844 women treated breast cancer 270 hospitals 6405 women surveyed quality life 18 months surgery breast appearance emotional wellbeing physical wellbeing quantified 0 100point scales linear multiple regression models controlling range baseline prognostic factors used compare scores patients complications scores notthe overall complication rate 102 complications associated little impairment women undergoing mastectomy without reconstruction delayed reconstruction association much larger flaprelated complications suffered immediate reconstruction breastappearance scores adjusted mean difference 238 95 confidence interval ci 310 166 emotional wellbeing scores adjusted mean difference 140 95 ci 220 60 patients much lower patient group implantrelated complications associated lower quality life surgical groupthere strong case prospectively collecting flapcomplication rates surgeon surgical unit level allowing patients access data make choices breast cancer surgery cancer 201712334607 2017 american cancer society