Raquel Perez-Lopez, Narmin Ghaffari Laleh, Faisal Mahmood, Jakob Nikolas Kather
A guide to artificial intelligence for cancer researchers
Nature reviews. Cancer
childhood asthma highly prevalent chronic disease failure implement patient education programmes may result increased morbidity despite availability distinct diagnostic therapeutic approaches patients lower socioeconomic status ses tend higher asthma prevalence moreover progression asthma significantly influenced factors health literacy childrens specific knowledge condition trial primary objective evaluate whether asthma education enhances specific disease understanding children asthma primary outcome secondary objectives include evaluating training effects health literacy retention rates information children asthma control test cact score frequency emergency room physician visits secondary outcomes whether ses influences training effects address research objectives study comprises two projects first subproject investigate influence asthma training development disease understanding health literacy second subproject analyse influence ses outcome children participating asthma training research designed comparative nonrandomised study involving two paediatric groups ages 7 14 years diagnosed asthma intervention group undergoes standardised psychoeducational asthma training certified centre associated paediatricians private practice germany following recommendations arbeitsgruppe asthmaschulung im kindes und jugendalter ev national association aiming establish uniform guidelinebased standards patient education children adolescents comparison group receives significantly shorter period education instruction usage asthma medication outpatient clinics data collected patients parents three specific survey time points based standardised toolsto describe mean differences intervention control group time subproject 1 repeatedmeasures analysis variance anova conducted subproject 2 multivariate linear regression analysis used analyse variables determining changes specific disease understanding health literacy including ses sample size calculation based mixed anova model two groups two measurements resulting total 126 participants protocols positive ethics approval obtained wittenherdecke university germany s159 2023 application submission 24 june 2023 final vote 10 july 2023 furthermore study registered german clinical trials register drks drks00032423 application submission 3 august 2023 final approval 4 august 2023 results disseminated among experts participants published peerreviewed international journal open access drks00032423