Melissa K Thomas, Ashleigh Gilligan, Jenna Lawson, Ted Lau
Breast Cancer Knowledge Among Amish and Mennonite Women
Journal of cancer education : the official journal of the American Association for Cancer Education
alcoholinduced facial flushing phenotype flushing common among east asians despite small intake alcohol experience heightened levels acetaldehyde group1 carcinogen turn causes unpleasant symptoms redness acting robust protective mechanism consuming alcohol however individuals genetic trait exhibit weakened alcohol restraint increases risk developing alcoholrelated cancers esophageal headneck cancer ten times although flushing phenomenon crucial public health paucity studies comprehensively investigated effect flushing genotype alcohol consumption large group east asians controlling various sociodemographic healthrelated variables country level twoyear crosssectional study aimed explore effect flushing drinking behavior koreans examine whether effect varies across sociodemographic healthrelated factors used data korea national health nutrition examination survey 20192020 conducted korea disease control prevention agency sample comprised 10660 korean adults study investigated association 26 variables including flushing drinking frequency amount effect flushing examined without adjusting 25 variables using multinomial logistic regression analysis additionally tested interaction effect flushing conducted simple effect analysis ensure unbiased results employed complex sample design elements including strata clusters weights obtain unbiased results raoscott 2 test ttest multinomial logistic regression analysis suppressive effect flushing significant across pronounced categories alcohol consumption significance level 001 2019 ranges standardized regression slopes odds ratios 670 1125 078 050 frequency 537 1764 073 036 amount respectively effect became somewhat stronger adjusted confounders effect also exhibited overall stronger trend severity alcohol consumption increased betas odds ratios consistently smaller 2020 compared previous year simple effect analysis revealed diminished alcoholsuppressive effect flushing alcohol consumption specific groups eg low levels education limited family support physical labor healthrelated issues findings suggest flushing suppresses drinking koreans overall little effect certain vulnerable populations therefore health authorities conduct targeted epidemiological studies assess drinking patterns disease profiles particularly regarding alcoholrelated cancers establish effective preventive measures tailored population