Elianna Kaplowitz|Sancia Ferguson|Marta Guerra|Carl A. Laskin|Jill P. Buyon|Michelle Petri|Michael D. Lockshin|Lisa R. Sammaritano|D. Ware Branch|Joan T. Merrill|Patricia Katz|Jane E. Salmon
Contribution of Socioeconomic Status to Racial/Ethnic Disparities in Adverse Pregnancy Outcomes Among Women With Systemic Lupus Erythematosus
Hospital for Special Surgery|University of California, San Francisco|Hospital for Special Surgery|CReATe Fertility Centre|University of Toronto|New York University|Johns Hopkins Medicine|Johns Hopkins University|Hospital for Special Surgery|Cornell University|Hospital for Special Surgery|Cornell University|Intermountain Healthcare|University of Utah|Oklahoma Medical Research Foundation|University of California, San Francisco|Hospital for Special Surgery|Cornell University
objective examined rates adverse pregnancy outcomes apo raceethnicity among women systemic lupus erythematosus sle without antiphospholipid antibodies apl whether socioeconomic status ses accounted differences methods data promisse predictors pregnancy outcome biomarkers antiphospholipid antibody syndrome systemic lupus erythematosus study multicenter study enrolled 346 patients sle 62 patients sle apl 50 white 20 african american 17 hispanic 12 asianpacific islander measures ses educational attainment median community income community education logistic regression analyses conducted determine odds apo racialethnic group controlling first age clinical variables ses results frequency apo white women sle without apl 29 11 respectively african american hispanic women approximately 2fold greater african american women sle alone adjustment clinical variables attenuated odds ratio 27 95 confidence interval 95 ci 1355 23 95 ci 1151 additional adjustment ses longer significant differences apo compared whites contrast sle patients apl whites african americans hispanics markedly higher risks apo compared white sle patients without apl 35 95 ci 1477 124 95 ci 19798 104 95 ci 25424 respectively accounted clinical ses covariates conclusion finding suggests african american women sle without apl ses factors key contributors disparities apo despite monthly care experts whereas factors contribute disparities sle apl