Qiyan Mu, Jenice Guzman-Clark, Anna G Etchin, Sheila Cox Sullivan, Catherine Battaglia
Exploring the Roles, Functions, and Work Experiences of Nurse Scientists in the Veterans Health Administration
The Journal of nursing administration
background alcohol use disorder aud one common substance use disorders globally chronic mental illness characterized frequent relapses hence preventing relapse one important aspects management patients aud aims study aimed compare role acamprosate baclofen anticraving agents patients diagnosed aud settings design 12week interventional followup study conducted department psychiatry n medical college tertiary care teaching hospital agra uttar pradesh india methods materials patients aud enrolled study following medical management alcohol withdrawal symptoms patients alternately assigned receive either acamprosate baclofen followed 12 weeks measures compare effectiveness two medications craving measured using penn alcohol craving scale pacs days first alcohol consumption days relapse number drinks consumed one occasion number patients completed study number patients remained abstinent throughout duration study descriptive statistics used present data unpaired ttest fishers exact test used compare two groups results total 63 patients enrolled study following medical management alcohol withdrawal symptoms one week 50 7937 patients retained study hence 50 patients assigned treatment either acamprosate baclofen alternately 11 ratio 32 64 patients started medications completed study available analysis end 12 weeks acamprosatetreated patients found less severe cravings p 001 alcohol end study also consumed less number drinks single occasion p 005 variables considered study namely days first alcohol consumption days relapse previous drinking pattern number patients dropped study versus completed study abstinent versus relapsed statistically significant difference noted conclusion acamprosatetreated patients significantly lesser cravings alcohol consumed lesser number drinks one occasion compared baclofentreated patients 12week study