Yue Xu, Wanxia Zhang, Kexin Zhang, Min Feng, Tianqi Duan, Yilin Chen, Xuexiang Wei, Yanlin Luo, Guoxin Ni
Basketball training frequency is associated with executive functions in boys aged 6 to 8 years
Frontiers in human neuroscience
prediction binding sites transcription factors important understand latter regulate gene expression regulation modulated therapeutic purposes consistent number references address issue different approaches machine learning one successful nevertheless note many approaches fail propose robust meaningful method embed genetic data analysis try overcome problem proposing bidirectional transformerbased encoder empowered bidirectional longshort term memory layers capsule layer responsible final prediction evaluate efficiency proposed approach use benchmark chipseq datasets five cell lines available encode repository a549 gm12878 hepg2 h1hesc hela results show proposed method predict tfbs within five different cell lines well moreover crosscell predictions provide satisfactory results well experiments conducted across cell lines reinforced analysis five additional lines used test model trained using others results confirm prediction across cell lines remains high allowing extensive crosstranscription factor analysis performed several indications interest molecular biology may drawn