Victor Sturesson, Peter Marforio, Arlind Reuter, Kajsa Johansson, Eva Ageberg
Youth handball concussion prevention strategies: a workshop-based study with experts and end users
BMJ open sport & exercise medicine
much published qtl detection complex traits using biparental multiparental crosses linkage analysis diversity panels gwas studies successful detection transferability results real applications proven difficult combined qtl detection approach using prebreeding populations utilized intensive phenotypic selection target trait across multiple plant generations combined rapid generation turnover ie speed breeding allow cycling multiple plant generations year reasoning qtl mapping information would complement selection process identifying genome regions selection within relevant germplasm questions answer location genomic regions determining response selection origin favourable alleles within pedigree used data prebreeding program aimed pyramiding different resistance sources fusarium crown rot elite susceptible wheat backgrounds population resulted complex backcrossing scheme involving multiple resistance donors multiple elite backgrounds akin magic population 985 genotypes total founders two major offspring layers within pedigree significant increase resistance level observed ie positive response selection selection process 17 regions significantly associated response identified using gwas approach regions included known qtl well potentially novel regions contributing resistance fusarium crown rot addition able trace back sources favourable alleles qtl demonstrate qtl detection using breeding populations selection target trait identify qtl controlling target trait frequency favourable alleles increased response selection thereby validating qtl detected valuable opportunistic approach provide qtl information easily transferred breeding applications