Jean B. Nachega|Donald G. Skinner|Larissa Jennings|Jessica F. Magidson|Frederick L. Altice|Jessica G. Burke|Richard Lester|Olalekan A. Uthman|Amy R. Knowlton|Mark F. Cotton|Jean Anderson|Gerhard Theron
Acceptability and feasibility of mHealth and community-based directly observed antiretroviral therapy to prevent mother-to-child HIV transmission in South African pregnant women under Option B+: an exploratory study
University of Pittsburgh|Western Cape Department of Health|Training Programs in Epidemiology and Public Health Interventions Network|Bloomberg (United States)|Massachusetts General Hospital|Yale University|University of Pittsburgh|University of British Columbia|University of Warwick|Stellenbosch University|Bloomberg (United States)|Johns Hopkins Medicine|Johns Hopkins University|Western Cape Department of Health
objective examine acceptability feasibility mobile health mhealthshort message service sms communitybased directly observed antiretroviral therapy cdot interventions improve antiretroviral therapy art adherence preventing mothertochild human immunodeficiency virus hiv transmission pmtctdesign methods mixedmethod approach usedtwo qualitative focus group discussions hivinfected pregnant women n20 examined acceptability feasibility two art adherence interventions pmtct 1 sms text messaging 2 patientnominated cdot supportersadditionally 109 hivinfected pregnant south african women 1830 years old receiving pmtct services singletablet antiretroviral therapy regimen pregnancy breastfeeding continuing life option b interviewed mobile phone access sms use potential treatment supporterssetting community primary care clinic cape town south africaparticipants hivinfected pregnant women main outcomes acceptability feasibility mhealth cdot interventionsresults among 109 women interviewed individual mobile phone access sms use high 90 881 women interested receiving sms art adherence support messages reminders motivation medication updatesnearly women 95 identified least one person close disclosed hiv status would nominate cdot supporterfocus group discussions revealed cdot supporters adherence text messages valued concerns regarding supporter time availability risk unintended hiv status disclosure expressedconclusion mhealth andor cdot supporter interventions improve art adherence feasible settinghowever safe hiv status disclosure treatment supporters confidentiality text messaging content hiv art deemed crucial