Preet K. Dhillon|Prashant Mathur|A Nandakumar|Christina Fitzmaurice|G Anil Kumar|Ravi Mehrotra|Deepak Shukla|Goura Kishor Rath|Prakash C. Gupta|Rajaraman Swaminathan|JS Thakur|Subhojit Dey|Christine A. Allen|Rajendra Badwe|Rajesh Dikshit|Rupinder Singh Dhaliwal|Tanvir Kaur|Amal Ch Kataki|Rudrapatna N. Visweswara|P Gangadharan|Eliza Dutta|Melissa Furtado|Chris M Varghese|Deeksha Bhardwaj|Pallavi Muraleedharan|Christopher M Odell|Scott Glenn|Manjit Singh Bal|P. P. Bapsy|James R. Bennett|Vijay Kumar Bodal|Joy Kumar Chakma|Sekhar Chakravarty|Meesha Chaturvedi|Priyanka Das|Vinay Deshmane|Nitin Gangane|James D. Harvey|Padmavathy Amma Jayalekshmi|Kaling Jerang|Sarah Johnson|P.K. Julka|Debnath Kaushik|Vinotsole Khamo|Shravani Koyande|Michael Kutz|W B Langstieh|K B Lingegowda|Rajeev Mahajan|Jagadish Mahanta|Gautam Majumdar|N Manoharan|Aleyamma Mathew|Bhagwan M. Nene|Sanghamitra Pati|P K Pradhan|Vinod Raina|Rama Ranganathan|C. Ramesh|Krishnan Sathishkumar|Kathryn Schelonka|Paul Stolzmann|Katya Anne Shackelford|Janmesh Shah|V. Shanta|Jagannath Dev Sharma|Abhishek Shrivastava|Sopai Tawsik|Brij Bhushan Tyagi|K Vaitheeswaran|Elizabeth Vallikad|Yogesh Kumar Verma|Eric Zomawia|Stephen S Lim|Theo Vos|Rakhi Dandona|K. Srinath Reddy|Mohsen Naghavi|Christopher J L Murray|Soumya Swaminathan|Lalit Dandona
The burden of cancers and their variations across the states of India: the Global Burden of Disease Study 1990–2016
h3backgroundh3 previous efforts report estimates cancer incidence mortality india different parts include national cancer registry programme reports sample registration system cause death findings cancer incidence five continents series globocan present comprehensive picture patterns time trends burden total cancer specific cancer types state india estimated part global burden diseases injuries risk factors study gbd 2016 systematic compilation readily available h3methodsh3 used accessible data multiple sources including 42 populationbased cancer registries nationwide sample registration system india estimate incidence 28 types cancer every state india 1990 2016 deaths disabilityadjusted lifeyears dalys caused part gbd 2016 present incidence dalys death rates cancers together trends types cancers highlighting heterogeneity burden specific types cancers across states india also present contribution major risk factors cancer dalys india h3findingsh3 83 95 uncertainty interval ui 7986 total deaths 50 4655 total dalys india 2016 due cancer double contribution cancer 1990 however agestandardised incidence rate cancer change substantially period agestandardised cancer daly rate 26 times variation across states india 2016 ten cancers responsible highest proportion cancer dalys india 2016 stomach 90 total cancer dalys breast 82 lung 75 lip oral cavity 72 pharynx nasopharynx 68 colon rectum 58 leukaemia 52 cervical 52 oesophageal 43 brain nervous system 35 cancer among cancers agestandardised incidence rate breast cancer increased significantly 407 95 ui 70856 1990 2016 whereas decreased stomach 397 343440 lip oral cavity 64 04186 cervical 397 265573 oesophageal cancer 312 279349 leukaemia 161 43242 found substantial interstate heterogeneity agestandardised incidence rate different types cancers 2016 33 times 116 times variation four frequent cancers lip oral breast lung stomach tobacco use leading risk factor cancers india highest proportion 109 cancer dalys could attributed 2016 h3interpretationh3 substantial heterogeneity statelevel incidence rate health loss trends different types cancer india 26year period taken account strengthen infrastructure human resources cancer prevention control national state levels efforts focus ten cancers contributing highest dalys india including cancers stomach lung pharynx nasopharynx colon rectum leukaemia oesophageal brain nervous system addition breast lip oral cavity cervical cancer currently focus screening early detection programmes h3fundingh3 bill melinda gates foundation indian council medical research department health research ministry health family welfare government india