Mathieu Miron, Robert Nadon
Inferential literacy for experimental high-throughput biology
Trends in genetics : TIG
family nurse partnership intensive home visiting programme adolescent mothers aimed evaluate effectiveness family nurse partnership outcomes age 7 using national administrative data created linked cohort mothers aged 1319 using data health educational childrens social care defined mothers enrolled family nurse partnership using family nurse partnership system data propensity scores used create matched groups analysis one hundred thirtysix local authorities england active family nurse partnership sites 2010 2017 mothers aged 1319 last menstrual period live births april 2010 march 2019 living family nurse partnership catchment area firstborn children family nurse partnership includes 64 home visits family nurse early pregnancy childs second birthday combined usual health social care controls received usual health social care indicators child maltreatment hospital admissions injurymaltreatment referral social care services child health development hospital utilisation education outcomes maternal hospital utilisation educational outcomes 7 years following birth family nurse partnership information system hospital episode statistics national pupil database 110520 eligible mothers 25680 232 enrolled family nurse partnership enrolment rates varied across 122 sites range 1168 areas eligible mothers lower enrolment rates enrolment higher among mothers aged 1315 52 1819 yearolds 21 indicators child maltreatment found evidence association family nurse partnership indicators child maltreatment except increased rate unplanned admissions maltreatmentinjuryrelated diagnoses age 2 children born family nurse partnership mothers 66 vs 57 relative risk 115 95 confidence interval 107 124 child health developmental outcomes weak evidence children born family nurse partnership mothers likely achieve good level development age 5 575 vs 554 relative risk 105 95 confidence interval 100 109 maternal outcomes evidence family nurse partnership mothers less likely subsequent delivery within 18 months index birth 84 vs 93 relative risk 092 95 confidence interval 088 097 younger vulnerable mothers received higher numbers visits likely achieve fidelity targets meeting fidelity targets associated outcomes bias indication variation intervention usual care time areas may limited ability detect effects multiple testing may led spurious significant results study supports findings evaluations family nurse partnership showing evidence benefit maltreatment outcomes measured administrative data amongst outcomes measured found weak evidence family nurse partnership associated improvements child development school entry reduction rapid repeat pregnancies evidence increased healthcareseeking mother child future evaluations capture better measures family nurse partnership interventions usual care information maternal risk factors additional outcomes relating maternal wellbeing study registered nihr crn portfolio 42900 award funded national institute health care research nihr health social care delivery research programme nihr award ref 179919 published full health social care delivery research vol 12 11 see nihr funding awards website award information