Amanda Nga-Sze Mak|Justin C. Y. Wu|Yawen Chan|Francis K.L. Chan|Joseph J.Y. Sung|S. Lee
Dyspepsia is strongly associated with major depression and generalised anxiety disorder ? a community study
Shatin Hospital|Chinese University of Hong Kong|Chinese University of Hong Kong|Chinese University of Hong Kong|Chinese University of Hong Kong|Chinese University of Hong Kong
relationship dyspepsia psychiatric comorbidity anxiety depression poorly defined previous studies limited lack standardised diagnostic criteriato examine prevalence comorbidity dyspepsia defined rome iii 6month duration dsmivtr generalised anxiety disorder gad major depressive episodes mde general populationa random populationbased telephone survey done using questionnaire symptoms rome iii dyspepsia dsmivtr gad mde chronological relationshipof 2011 respondents 80 currently rome iii dyspepsia 38 reported gad 124 reported mde respectively dyspeptic subjects twofold increased risk gad 203 95 ci 106389 p 0001 threefold increased risk mde 356 95 ci 233543 p 0001 mde gad often coincided dyspepsia onset dyspepsia 248 95 ci 165372 p 0001 mde 239 95 ci 164346 p 0001 female sex 165 95 ci 121223 p 0001 independently predicted frequent medical consultations gad independently predicted high investigation expenditure 465 95 ci 1151870 p 003with stringently adopted rome iii dsmivtr criteria dyspepsia strongly associated often coincident onset generalised anxiety disorder major depressive episodes community excessive healthcare utilisation alert clinicians risk psychiatric comorbidity