P Cugini
[Identification and description of a new epistemological category of inferential reasoning related to meta-naturalistic science]
La Clinica terapeutica
pediatriconset multiple sclerosis poms associated significant cognitive physical disability whether disability translates differences educational achievements earnings unknown evaluate association poms educational level income throughout adulthood prospective registerbased cohort study individuals poms populationbased matched reference cohort conducted using nationwide microdata linked registers sweden january 1 1990 december 31 2016 analyses completed may 1 2019 september 1 2020 772 persons poms identified swedish ms registry 485 onset period 1980 2014 socioeconomic data available general population reference cohort without multiple sclerosis ms n 4850 randomly selected full swedish population matched 101 age sex country birth pediatriconset ms diagnosed neurologist onset 18 years age highest educational level elementary school high school university assessed using logistic regression income measured mean annual earnings paid work us dollars compared using tobit models net annual sickness absence disability pension days compared using zeroinflated negative binomial regression earnings days receiving disability benefits compared within 4 age periods 1924 2534 3544 4554 years median age cohort poms n 485 matched reference cohort n 4850 2016 32 years interquartile range 2640 years participants women 348 718 poms cohort 3480 718 matched reference cohort persons poms less likely persons matched reference cohort attend university odds ratio 080 95 ci 066097 significantly lower annual earnings reference cohort ranging 1618 95 ci 2558 678 youngest age period 10 683 95 ci 18 187 3178 eldest persons poms received higher rates disability benefits sickness absence days youngest age period rate ratio 306 95 ci 208452 disability pension days oldest age period rate ratio 143 95 ci 111185 study suggests poms associated less educational achievement lower earnings greater use disability benefits throughout workingage life span adults persons poms never earned much counterparts without ms exhibited heavier reliance disability benefits