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biotechnology offers solutions opportunities meet various societal demands thereby contributing significant scientific advancements study aimed characterize technological development biotechnology healthcare sector state rio grande sul brazil 2016 2022 analyzing patents filed granted public private higher education institutions data collection quantitative exploratory approach employed using statistical methods patent analysis institutions patent database brazilian national institute industrial property inpi focusing patents related healthcare field data collected october november december total 580 patent records collected inpi belonging sections c international patent classification ipc related educational institutions furthermore study highlighted higher education institutions higher number patents healthcare field results provide understanding strategic areas technological development biotechnology rio grande sul brazil