Rachel C. Vreeman|Scanlon
Current strategies for improving access and adherence to antiretroviral therapies in resource-limited settings
Indiana University – Purdue University Indianapolis|AMPATH|Indiana University – Purdue University Indianapolis|AMPATH
rollout antiretroviral therapy art significantly reduced human immunodeficiency virus hivrelated morbidity mortality good clinical outcomes depend access adherence treatmentin resourcelimited settings 90 worlds hivinfected population resides data barriers treatment emerging contribute low rates uptake hiv testing linkage retention hiv care systems suboptimal adherence rates therapya review literature reveals limited evidence inform strategies improve access adherence majority studies subsaharan africadata observational studies randomized controlled trials support homebased mobile antenatal care hiv testing taskshifting doctorbased nursebased lower level provider care adherence support education counseling mobile phone messaging servicesstrategies limited evidence include targeted hiv testing couples family members art patients decentralization hiv care including homeand communitybased art programs adherence promotion peer health workers treatment supporters directly observed therapythere little evidence improving access adherence among vulnerable groups women children adolescents highrisk populations addressing major barriersoverall studies number suffer methodological issuesrecommendations research include health information technology sociallevel factors like hiv stigma new research directions costeffectiveness operations implementationfindings review make compelling case data guide strategies improve access adherence treatment resourcelimited settings