Soultana Macridis, Enrique Garcia Bengoechea, Alex M McComber, Judi Jacobs, Ann C Macaulay
Active transportation to support diabetes prevention: Expanding school health promotion programming in an Indigenous community
Evaluation and program planning
sex age education associated level cognitive performance investigated whether factors modulate change cognitive performance midlife leveraging longitudinal data cardiovascular risk young finns study yfs participants yfs cohort performed computerbased cambridge neuropsychological test automated battery cantab 2011 2018 n 1671 age 4156 years 2018 overall cognitive performance domains representing learning memory working memory reaction time information processing extracted common principal component analysis longitudinal cognitive data linear models adjusted baseline cognitive performance used study association sex age education changes overall cognitive performance cognitive domains cognitive performance decreased domains overall cognition 056 sd p 0001 working memory 081 sd p 0001 learning memory 070 sd p 0001 reaction time 006 sd p 0019 information processing 003 sd p 0016 decrease working memory information processing greater females compared males cognitive performance decreased older participants domains education alleviated decrease cognitive performance domains except reaction time beneficial effect education greater males study describes natural course agingrelated changes cognitive performance midlife critical time window early prevention clinical cognitive decline findings provide reference studies focusing determinants pathological cognitive decline deviating normal changes cognitive performance