Jorien Veldwijk|Mattijs Lambooij|Frank G.J. Kallenberg|Henk J. van Kranen|Annelien L. Bredenoord|Evelien Dekker|Henriëtte A. Smit|G. Ardine de Wit
Preferences for genetic testing for colorectal cancer within a population-based screening program: a discrete choice experiment
National Institute for Public Health and the Environment|National Institute for Public Health and the Environment|Academic Medical Center|National Institute for Public Health and the Environment|University Medical Center Utrecht|Academic Medical Center|University Medical Center Utrecht|University Medical Center Utrecht
study explored individuals preferences genetic testing colorectal cancer crc screening situation willingness participate genetic testing lynch syndrome familial adenomatous polyposis fap familial colorectal cancer fcc purpose 532 respondents aged 5565 years completed discrete choice experiment using panel latent class models preferences two screening situation characteristics probability genetically predisposed probability developing crc screening test characteristics frequency preventive colonoscopies crc survival estimated based preferences respondents willingness participate three screening initiatives estimated lowereducated respondents respondents express serious anxiety worries found colonoscopy frequency probability developing crc relatively important survival relatively less important compared highereducated respondents respondents express anxiety worries differences preferences resulted opposite preferences participation fcc fap screening conclusion general population willing participate genetic screening crc individuals suspected genetic familial crc least informed increased risk genetically predisposed importance participating preventive followup colonoscopies order maximize survival