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aim article present introduction mandatory vertically integrated course research methodology medical curriculum school medicine split croatia organized course 2010 total 270 hours 6year curriculum first year 50 hours students learned basic principles scientific method structure scientific article basic statistical concepts data analysis interpretation presentation second year 25 hours students applied knowledge first year real examples research data answer research hypothesis present results conclusions students guided process making hypothesis analyzing data interpreting constructing tables figures writing short research report end course formally presented results students course teachers using powerpoint slides third year 25 hours devoted mastering concepts basic skills evidencebased medicine ebm course fourth year 25 hours integrated clinical courses internal medicine neurology psychiatry structured journal club fifth year 25 hours teaching devoted developing research plan graduation thesis students conduct sixth year sixth year 120 hours devoted execution research planned fifth year including data collection data analysis interpretation thesis writing defense new course succeeded increasing students knowledge skills critical thinking ebm prepared lifelong learning medicine