Daniel J Lugar, Ganesh Sriram
Isotope-assisted metabolic flux analysis as an equality-constrained nonlinear program for improved scalability and robustness
PLoS computational biology
prevalent use antibiotics hospitals results antimicrobial resistance amr rising mortality substantial financial burden study assessed current pattern antibiotic use among inpatients tertiary hospitals bangladesh august november 2022 conducted point prevalence survey pps four tertiary hospitals dhaka bangladesh whodirected pps methodology tools followed data collection descriptive multivariate statistics performed using stata version 15 1063 hospitalized patients antibiotics prescribed 735 7811063 95ci 708761 patients total 1164 antibiotics prescribed 491 patients consumed multiple antibiotics 314 patients prescribed antibiotics based microbiology results reasons antibiotic prescribing mentioned 193 patients infants aor 852 pvalue 0001 neonates aor 432 pvalue 0001 likely consume antibiotics compared adults cephalosporins accounted majority 540 antibiotics used hospitals none hospitals antibiotic use guidelines consumption watch group antibiotics empirically among age groups demonstrates irrational antibiotic usage bangladeshi hospitals implementation tailored stewardship program antibiotic use guidelines prescriberpatient awareness could improve rational use antibiotics