Chris Power|Barbara J. Jefferis|Orly Manor
Childhood Cognition and Risk Factors for Cardiovascular Disease in Midadulthood: The 1958 British Birth Cohort Study
University College London|Medical Research Council|University College London|Medical Research Council|University College London|Medical Research Council
sought establish whether associations childhood cognition risk factors cardiovascular disease adulthood explained common causes adult social position health behaviorwe analyzed associations cognition age 11 cardiovascular disease risk factors age 45 1958 british birth cohort n9377 without adjustment covariatesgeneral ability inversely associated systolic diastolic blood pressure glycosylated hemoglobin triglycerides women body mass index waist circumference systolic blood pressure decreased 047 mm hg 95 confidence interval ci090 005 1standarddeviation increase ability separate adjustment social class birth education level adulthood adult social class health behaviors reduced associations respectively 14 34 36 50 14 36 24 73 full adjustment reduced associations ability risk factors age 45 years 43 92 abolishing associationsincrements across distribution childhood cognition associated improvements cardiovascular risk profile midlife associations primarily mediated adult health behavior social destinations