Reinhard Kaiser|Rebecca Bunnell|Allen W. Hightower|Andrea A. Kim|Peter Cherutich|M. Mwangi|Tom Oluoch|Sufia Dadabhai|Patrick Mureithi|Nelly Mugo|Jonathan Mermin
Factors Associated with HIV Infection in Married or Cohabitating Couples in Kenya: Results from a Nationally Representative Study
University of California, San Francisco|National Aids Control Council|Kenyatta National Hospital|University of Nairobi
order inform prevention programming analyzed hiv discordance concordance within couples kenya aids indicator survey kais 2007kais nationally representative populationbased serosurvey examined demographic behavioral indicators serologic testing hiv hsv2 syphilis cd4 cell counts 15853 consenting adults aged 1564 years analyzed interview blood testing data sexual partnership level married cohabitating couples multivariable regression models used identify factors independently associated hiv discordant concordant statusof 3256 couples identified survey 2748 844 interview blood testing data overall 38 couples concordantly infected hiv 58 one partner infected translating 338000 discordant couples kenya 836 hivinfected kenyans living married cohabitating couples neither partner knew hiv status factors independently associated hivdiscordance included young age women aor 15 95 ci 1218 p00001 increasing number lifetime sexual partners women aor 15 95 ci 1318 p00001 hsv2 infection either partners aor 41 95 ci 2372 p00001 lack male circumcision aor 16 95 ci 1025 p 0032 independent factors hivconcordance included hsv2 infection partners aor 65 95 ci 23187 p 0001 lack male circumcision aor 18 95 ci 1033 p 0043couple prevention interventions begin early relationships include mutual knowledge hiv status reduction outside sexual partners promotion male circumcision among hivuninfected men mechanisms effective prevention suppression hsv2 infection also needed