Yi Xie, Ishith Seth, David J Hunter-Smith, Warren M Rozen, Marc A Seifman
Investigating the impact of innovative AI chatbot on post-pandemic medical education and clinical assistance: a comprehensive analysis
ANZ journal of surgery
high mutation rate rna virus results emergence novel mutants may escape immunity activated original wildtype strain however many go extinct stochasticity due small initial number infected cells previous paper studied probability escaping stochastic extinction novel mutant faster rate infection resistant drug suppresses wildtype virus study examine effect escaping immune reaction host based continuoustime branching process timedependent rates conclude chance mutant strain established formula see text decreases time formula see text since wildtype infection mutant produced number novel mutants escape extinction risk peak soon wildtype infection number novel escape mutations produced per patient early phase host infection small strong weak immune responses attains maximum value immune activity intermediate strength