Gregory Stewart, Collin A Webster, Ali Brian, David Stodden, Cate A Egan, R Glenn Weaver
Systematically Observed Movement Integration in a Low Socioeconomic School District: A Cross-Sectional, Observational Study
American journal of health promotion : AJHP
schizophrenia severe public health problem one top ten causes disability affecting 11 worlds population paliperidone new atypical antipsychotic used treat schizophrenia several case reports unexpected adverse drug reactions paliperidone consistently reported around world purpose study detect signals adverse events aes paliperidone treatment using korea institute drug safety risk managementkorea adverse event reporting system database kidskd applied datamining techniques based disproportionality analysis kidskd consisting spontaneously reported ae reports related atypical antipsychotics january 2009 december 2018 calculated three datamining indices paliperidone compared atypical antipsychotics defined signals satisfied three criteria indices checked signals identified included drug labels south korea usa uk japan germany france total number suspected ae reports related atypical antipsychotics kidskd january 2009 december 2018 43970 among number ae reports related paliperidone 9453 overall 13 signals seborrhea hallucination obesity gingivitis intervertebral disorder classified newly detected meaningful signals detected new ae signals paliperidone listed drug labels six countries many related psychotic symptoms metabolic problems endocrine disorders