Francis Eriga, Godfrey Gulom, John Bosco Alege
Predictors of under-weight among children younger than 24 months in Nimule Border Town, Eastern Equatoria State, South Sudan: a community-based cross sectional study
BMC public health
cydtdv dengvaxia first dengue vaccine approved launched brazil 2015 individuals aged 944 years aimed estimate effectiveness cydtdv preventing symptomatic dengue cases campaign targeting individuals aged 1527 years selected municipalities paran brazil additionally examined whether history dengue recorded surveillance system modified vaccines effectiveness conducted casecohort analysis comparing frequency vaccination least one dose cydtdv individuals dengue confirmed rtpcr identified surveillance system 2019 2020 vaccination coverage target population moreover casecontrol design using weighted controls assessed documented history dengue modifier vaccines effectiveness used logistic randomeffects regression model data clustered municipalities incorporating covariates incidence dengue campaign age sex calculated vaccine effectiveness 1relative risk x 100 1869 dengue cases identified vaccination frequency significantly lower overall vaccination coverage target population 503 vs 572 respectively overall 213 95 confidence interval ci 134284 individuals documented history dengue vaccination 71 95 ci 5880 reducing incidence dengue however vaccination associated significant reduction overall dengue case risk individuals without documented history dengue 12 95 ci 21 36 last stratum vaccination associated reduced cases due denv1 denv4 excess denv2 cases vaccination led significant reduction reported dengue cases within target population casecontrol design suggested reduction primarily driven benefits observed individuals documented history dengue endemic regions limited serological testing facilities previous history dengue diagnosis recorded epidemiological surveillance could used triage candidates cydtdv vaccination research supported sanofi