Judit Fekete, Zsuzsanna Pótó, Eszter Varga, Dóra Hebling, Márton Herold, Noémi Albert, Borbála Pethő, Tamás Tényi, Róbert Herold
The effect of reading literary fiction on the theory of mind skills among persons with schizophrenia and normal controls
Frontiers in psychiatry
study presents novel approach early detection cognitive impairment elderly approach incorporates use speech sound analysis multivariate statistics datamining techniques developed speech prosodybased cognitive impairment rating spcir distinguish cognitively normal controls elderly people mild alzheimers disease mad mild cognitive impairment mci using prosodic signals extracted elderly speech administering questionnaire two hundred seventythree japanese subjects 73 males 200 females ages 65 96 participated study authors collected speech sounds segments dialogue revised hasegawas dementia scale hdsr examination talking topics related hometown childhood school segments correspond speech sounds answers questions regarding birthdate t1 name subjects elementary school t2 time orientation q2 repetition threedigit numbers backward q6 many prosodic features possible extracted speech sounds including fundamental frequency formant intensity features melfrequency cepstral coefficients refined using principal component analysis andor feature selection authors calculated spcir using multiple linear regression analysis addition study proposes binary discrimination model spcir using multivariate logistic regression model selection receiver operating characteristic curve analysis reports sensitivity specificity spcir diagnosis control vs mcimad study also reports discriminative performances well thereby suggesting proposed approach might effective tool screening elderly mad mci