Jamie Brown|Susan Michie|Adam W A Geraghty|Lucy Yardley|Benjamin Gardner|Lion Shahab|John Stapleton|Robert A. West
Internet-based intervention for smoking cessation (StopAdvisor) in people with low and high socioeconomic status: a randomised controlled trial
University College London|Action on Smoking and Health|University of Southampton|King's College London|Cancer Research UK|Cancer Research UK|University College London|Action on Smoking and Health|University of Southampton|King's College London|Cancer Research UK|University College London|Action on Smoking and Health|University of Southampton|King's College London|Cancer Research UK|University College London|Action on Smoking and Health|University of Southampton|King's College London|Cancer Research UK|University College London|Action on Smoking and Health|University of Southampton|King's College London|Cancer Research UK|University College London|Action on Smoking and Health|University of Southampton|King's College London|Cancer Research UK|University College London|Action on Smoking and Health|University of Southampton|King's College London|Cancer Research UK|University College London|Action on Smoking and Health|University of Southampton|King's College London
internetbased interventions smoking cessation could help millions people stop smoking low unit costs however longterm biochemically verified evidence scarce interventions might less effective smokers low socioeconomic status high status lower online literacy engage websites aimed assess new interactive internetbased intervention stopadvisor smoking cessation designed particular attention directed people low socioeconomic statuswe online randomised controlled trial dec 6 2011 oct 11 2013 uk participants aged 18 years older smoked every day randomly assigned 11 receive treatment stopadvisor informationonly website randomisation automated unseen random number function embedded website establish treatment revealed online baseline assessment recruitment continued required sample size achieved high low socioeconomic status subpopulations participants researchers obtained data laboratory analyses masked treatment allocation primary outcome 6 month sustained biochemically verified abstinence main secondary outcome 6 month 7 day biochemically verified point prevalence analysis intention treat homogeneity intervention effect across socioeconomic subsamples first assessed establish whether overall separate subsample analyses appropriate study registered international standard randomised controlled trial number isrctn99820519we randomly assigned 4613 participants stopadvisor group n2321 control group n2292 2142 participants low socioeconomic status 2471 participants high status overall rate smoking cessation similar participants stopadvisor control groups primary 237 10 vs 220 10 participants relative risk rr 106 95 ci 089127 p049 secondary 358 15 vs 332 15 participants 106 093122 p037 outcomes however intervention effect differed across socioeconomic status subsamples 144 099209 p00562 137 102184 p00360 respectively stopadvisor helped participants low socioeconomic status stop smoking compared informationonly website primary outcome 90 8 1088 vs 64 6 1054 participants rr 136 95 ci 100186 p00499 secondary outcome 136 13 vs 100 10 participants 132 103168 p00267 improve cessation rates high socioeconomic status 147 12 1233 vs 156 13 1238 participants 095 077117 p061 222 18 vs 232 19 participants 096 081113 p064 respectivelystopadvisor effective informationonly website smokers low high socioeconomic status stopadvisor could implemented easily made freely available would probably improve success rates smokers low socioeconomic status seeking online supportnational prevention research initiative