Giancarlo Gomes, Gérson Tontini, Vania Montibeler Krause, Marianne Bernardes
Before and during COVID-19: the roles of transformational leadership, organizational culture and work-life balance in healthcare
Journal of health organization and management
evaluate whether traumatic brain injury tbi characteristics age injury recency injury predicts course neurocognitive decline andor increases conversion rates mild cognitive impairment mci dementia data obtained national alzheimers coordinating center participants 5085 years old 35 visits 2015 2022 without tbi history tbi 508 tbi 2382 groups stratified selfreported tbi history ie single tbi without loss consciousness loc single tbi loc multiple tbi without loc multiple tbi loc age recent tbi recency tbi mixed linear models compared neuropsychological composite trajectories executive functioningattentionspeed language memory global covarying age gender education apolipoprotein e4 status raceethnicity baseline diagnosis normal aging n 1720 mci n 749 dementia n 417 logistic binary regression examined mcidementia conversion rates slightly higher frequency mcidementia multiple tbis 50 60 without loc compared 39 tbi baseline longitudinal trajectories similar tbi history age injury recency injury impact neurocognitive trajectories conversion rates mcidementia ps 01 tbi history regardless injury characteristics age injury recency injury worsen neurocognitive decline mcidementia conversion additional longitudinal research diverse cohorts wider range tbi severity needed evaluate specific factors possible mechanisms tbi may increase dementia risk