Kolab Chhim|Gitau Mburu|Sovannary Tuot|Ratana Sopha|Vohith Khol|Pheak Chhoun|Siyan Yi
Factors associated with viral non-suppression among adolescents living with HIV in Cambodia: a cross-sectional study
Lancaster University|National Center for HIV/AIDS, Dermatology and STD|National University Health System|National University of Singapore
adolescents living hiv antiretroviral therapy art worse treatment adherence viral suppression mortality rates compared adults study investigated factors associated viral nonsuppression among adolescents living hiv cambodiaa crosssectional study conducted august 2016 among 328 adolescents living hiv aged 1517 years randomly selected 11 art clinics capital city phnom penh 10 provinces clinical immunological data including cd4 count viral load obtained medical records art clinics adolescents categorized achieved viral suppression latest viral load count 1000 ribonucleic acid rna copiesml multivariate logistic regression analysis performed identify factors independently associated viral nonsuppressionthe mean age participants 159 years sd 08 485 female median duration art 86 interquartile range 60106 years total 768 participants achieved viral suppression adjustment covariates likelihood viral nonsuppression remained significantly lower among adolescents olderaged 17 aor 046 95 ci 021098 art 9 years aor 035 95 ci 019064 recent cd4 count 672 aor 047 95 ci 026086 relative main daily caregiver aor 037 95 ci 017080 believe cure aids aor 040 95 ci 021075 compared reference group likelihood viral nonsuppression also remained significantly higher among adolescents first viral load 628 rna copiesml aor 181 95 ci 105408 among receiving hiv care treatment adult clinic aor 295 95 ci 156559the proportion adolescents living hiv viral suppression study relatively high 768 falls short global target 90 programs targeting younger adolescents adolescents transition pediatric adult care range interventions including psychosocial support treatment literacy could improve viral suppression outcomes