Kimberly A. Kaphingst|Colleen M. McBride|Christopher H. Wade|Sharon Hensley Alford|Lawrence C. Brody|Andreas D. Baxevanis
Consumers’ Use of Web-Based Information and Their Decisions About Multiplex Genetic Susceptibility Testing
Washington University in St. Louis|National Human Genome Research Institute|National Institutes of Health|National Human Genome Research Institute|National Institutes of Health|National Human Genome Research Institute|National Institutes of Health|Henry Ford Hospital|National Human Genome Research Institute|National Institutes of Health|National Human Genome Research Institute|National Institutes of Health
data exist inform concerns raised online directtoconsumer marketing genetic susceptibility tests offered commercial entities like 23andme navigenics dna direct multiplex initiative populationbased study healthy adults provides first opportunity evaluate use webbased decision tool conveyed information genetic susceptibility test influenced individuals test decisionsto inform ongoing debate whether individuals offered genetic susceptibility testing without involvement health care provider eg directtoconsumer testing make informed decisions testing guided online decision aidsparticipants 526 members large health maintenance organization aged 25 40 years old visited study website multivariate logistic regression models tested examine association website usage downstream test decisionsparticipants viewed average 29 4 pages introducing multiplex test 22 8 pages describing health conditions 32 15 pages describing genes page viewed participants likely describe decisionmaking easy odds ratio 104 95 confidence interval ci 101107 decide tested 108 95 ci 105111healthy adults study perceived webbased genomic information presented using evidencebased communications approaches helpful supporting decisions test test continued research needed ensure results generalize target groups lower literacy less internet savvy