Marina Reznik, Judith Wylie-Rosett, Mimi Kim, Philip O Ozuah
A classroom-based physical activity intervention for urban kindergarten and first-grade students: a feasibility study
Childhood obesity (Print)
total blood carbon monoxide tbco showed promising results improving accuracy co determinations blood presenting better stability different storage conditions therefore proposed alternative biomarker carboxyhemoglobin cohb co poisoning diagnosis however given current interpretation reference values exist cohb difficult implement tbco analysis routine therefore aimed determining tbco reference values postmortem co poisoning cases previously validated method tbco analysis via gas chromatographymass spectrometry applied cardiac peripheral cranial spleen blood samples collected 92 autopsies autopsy cases included 21 nonco related 71 corelated cases varying postmortem intervals pmi statistical analyses performed using statistical software r studio comparing lower higher pmi nonco related cases significant differences found suggests co formation degradation low pmis occur spleen blood showed potential alternative matrix co determinations cases sample availability issues needs evaluated co positive cases results cardiac blood corelated autopsies showed positive correlation cohb tbco values r 078 value lower found literature suggesting even though cohb tbco correlated potential underestimation true co exposure might occur cohb values taken consideration samples divided co exposure groups based cohb concentrations data obtained classification following tbco concentration groups proposed significant co exposure case 6 molml medium co exposure case 620 molml high co exposure case 20molml even higher number samples group would enable increase confidence results promising highlight importance tbco measurement