Mary J De Silva|Sara Cooper|Henry Lishi Li|Crick Lund|Vikram Patel
Effect of psychosocial interventions on social functioning in depression and schizophrenia: meta-analysis
London School of Hygiene & Tropical Medicine|University of Cape Town|London School of Hygiene & Tropical Medicine|University of Cape Town|Sangath|London School of Hygiene & Tropical Medicine
psychosocial interventions may contribute reducing burden mental disorders low middleincome lami countries improving social functioning evidence systematically reviewedsystematic review metaanalysis effect psychosocial interventions social functioning people depression schizophrenia lami countriesstudies identified database searching march 2011 randomised controlled trials included compared intervention group control group receiving placebo treatment usual random effects metaanalyses performed separately depressive disorders schizophrenia intervention typeof studies met inclusion criteria n 24 21 sufficient data include metaanalysis eleven depression trials showed good evidence moderate positive effect psychosocial interventions social functioning standardised mean difference smd 046 95 ci 024069 n 4009 ten schizophrenia trials showed large positive effect social functioning smd 084 95 ci 049119 n 1671 although seven trials low quality excluding substantially affect size direction effect although precision estimate substantially reduced smd 089 95 ci 005172 n 863psychosocial interventions delivered outpatient primary care settings effective improving social functioning people depression incorporated efforts scale services schizophrenia absence evidence highquality trials generalisabilty findings limited overrepresentation trials conducted populations hospital patients china highquality trials psychosocial interventions schizophrenia delivered outpatient settings needed