Aisha T. Langford|Ken Resnicow|Eileen Dimond|Andrea Denicoff|Diane St. Germain|Worta McCaskill?Stevens|Rebecca A. Enos|Angela Carrigan|Kathy Wilkinson|Ronald S. Go
Racial/ethnic differences in clinical trial enrollment, refusal rates, ineligibility, and reasons for decline among patients at sites in the National Cancer Institute's Community Cancer Centers Program
University of Michigan–Ann Arbor|University of Michigan–Ann Arbor|National Cancer Institute|National Cancer Institute|National Cancer Institute|National Cancer Institute|Emmes (United States)|Frederick National Laboratory for Cancer Research|Billings Clinic|Gundersen Health System
background study examined racialethnic differences among patients clinical trial ct enrollment refusal rates ineligibility desire participate research within national cancer institutes community cancer centers program ncccp clinical trial screening accrual log methods data 4509 log entries evaluated study four logistic regression models run using physicalmedical conditions enrollment ct patient eligible declined ct desire participate research dependent variables results age 65 years 151 95 ci 128179 males 228 95 ci 192271 nonhispanic black race 153 95 ci 12196 significantly associated physicalmedical conditions age 65 years significantly associated lower ct enrollment 083 95 ci 07098 males 078 95 ci 065094 higher grade level score consent form readability 09 95 ci 083097 significantly associated lower refusal rates consent page length 20 significantly associated lower odds desire participate research among ct decliners 075 95 ci 058098 conclusions racialethnic differences ct enrollment refusal rates desire participate research reason given ct refusal higher odds physicalmedical conditions associated older age males nonhispanic blacks better management physicalmedical conditions treatment may increase pool eligible patients cts future work examine role comorbidities sex age consent form characteristics ct participation cancer 2014120877884 2013 american cancer society