Thiago Junqueira Avelino?Silva|Flávia Campora|José Antônio Ésper Curiati|Wilson Jacob?Filho
Prognostic effects of delirium motor subtypes in hospitalized older adults: A prospective cohort study
Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo|Universidade de São Paulo
investigate association delirium motor subtypes hospital mortality 12month mortality hospitalized older adultsprospective cohort study conducted 2009 2015geriatric ward university hospital sao paulo brazilwe included 1409 consecutive admissions acutely ill patients aged 60 years excluded admissions endoflife care missing data main variables length stay shorter 48 hours consent participate givendelirium detected using confusion assessment method categorized hypoactive hyperactive mixed delirium primary outcomes time death hospital time death 12 months discharged sample comprehensive geriatric assessment performed admission included sociodemographic clinical functional cognitive laboratory variables clinical data documented upon death discharge multivariate analyses used cox proportional hazards models adjusted possible confounderswe included 1409 admissions mean age 80 years proportion inhospital deaths 19 cumulative mortality 38 12 months delirium occurred 47 admissions hypoactive delirium predominant motor subtype 53 followed mixed delirium 30 hyperactive delirium 17 hospital mortality rates respectively 33 34 15 verified hypoactive mixed delirium independently associated hospital mortality respective hazard ratios 243 95ci 164359 231 95ci 153350 delirium motor subtypes independently predictive 12month mortalityone three acutely ill hospitalized older adults suffered hypoactive mixed delirium died hospital clinicians aware hypoactive symptoms delirium whether shown exclusively alternation hyperactive symptoms indicative worse prognosis population