Kaiyang Song, Molly Hey, Rebecca Elizabeth Payne
Media depictions of primary care tele-consultation safety: analysis of UK newspapers
The British journal of general practice : the journal of the Royal College of General Practitioners
china third largest share global tuberculosis cases faces substantial challenge healthcare system result high burden multidrugresistant rifampicinresistant tuberculosis mdrrrtb study employs genomic epidemiological approach assess recent tuberculosis transmissions individuals identifying potential risk factors discerning role transmitted resistant isolates emergence drugresistant tuberculosis china conducted populationbased retrospective study 5052 mycobacterium tuberculosis mtb isolates 70 surveillance sites using whole genome sequencing wgs minimum spanning tree analysis identified resistance mutations epidemiological data analysis pinpointed transmission risk factors 5052 isolates 23 1160 formed 452 genomic clusters 856 387 transmissions occurring within counties individuals younger age larger family size new cases smear positive mdrrr higher odds recent transmission higher education university occupation nonphysical workers emerged protective factors least 614 251409 mdrrrtb likely result recent transmission mdrrr isolates previous treatment crude 277 smearpositive cor 207 larger family population cor 113 established risk factors findings highlight local transmission remains predominant form tb transmission china correspondingly drugresistant tuberculosis primarily driven transmission resistant tuberculosis isolates targeted interventions highrisk populations interrupt transmission within country likely provide opportunity reduce prevalence tuberculosis drugresistant tuberculosis