Polite Tshalibe, Jacinta Adrigwe, Susan Lucas
Clinicians' perspective of picture archiving and communication systems at Charlotte Maxeke Johannesburg Academic Hospital
SA journal of radiology
objectives main goal study investigate compare neural substrate two childrens profiles high intelligence quotient hiq methods two groups hiq children included either homogeneous homhiq n 20 heterogeneous iq profile hethiq n 24 defined significant difference verbal comprehension index perceptual reasoning index diffusion tensor imaging used assess white matter wm microstructure tractbased spatial statistics tbss analysis performed detect localize wm regional differences fractional anisotropy fa mean diffusivity axial ad radial diffusivities quantitative measurements performed 48 regions 21 fiberbundles wm results homhiq children presented higher fa hethiq children widespread wm regions including central structures associative intrahemispheric wm fasciculi ad also greater numerous wm regions totalhiq homhiq hethiq groups compared control group homhiq hethiq groups also differed hemispheric lateralization ad differences compared controls hethiq homhiq groups showed lateralization ratio leftright 138 078 respectively conclusions findings suggest inter intrahemispheric wm integrity enhanced hiq children neural substrate differs homhiq hethiq left hemispheric lateralization hethiq children concordant higher verbal index relative right hemispheric lateralization homhiq children concordant global brain processing adaptation capacities evidenced homogeneous iq