Carol R. Horowitz|Tatiana Sabin|Michelle Ramos|Lynne D. Richardson|Diane Hauser|Mimsie Robinson|Kezhen Fei
Successful recruitment and retention of diverse participants in a genomics clinical trial: a good invitation to a great party
Icahn School of Medicine at Mount Sinai|Icahn School of Medicine at Mount Sinai|Icahn School of Medicine at Mount Sinai|Icahn School of Medicine at Mount Sinai|Institute for Family Health|Bethel University|Icahn School of Medicine at Mount Sinai
african ancestry aa individuals inadequately included translational genomics research limiting generalizability findings benefits genomic discoveries populations already facing disproportionately poor health outcomes aimed determine impact stakeholderengaged strategies recruitment retention aa adult patients clinical trial testing renal risk variants nearly exclusive aasour academicclinicalcommunity team developed ten key strategies recognize aas barriers facilitators participation using electronic health records ehrs identified potentially eligible patients recruiters reached letters phone calls medical visitsof 5481 aa patients reached 51 ineligible 37 enrolled 4 declined 7 undecided enrollment finished retained 93 3month 88 12month followup enrolled likely female seen community sites reached active strategies declined retained likely female healthliterate older many patients low income low clinician trust perceive racism health care none attributes correlate retentionwith robust stakeholder engagement recruiters patients communities active approaches successfully recruited retained aa patients genomic clinical trial