Jan Bardelle, Hanna Abady, Michael Paulussen, Peter Lampen-Eberle, Hermann Kalhoff, Antje Pizzulli, Kirn Parasher, Patrick Brzoska, Malik Aydin, Claudia Kiessling
Study protocol of a prospective, interventional non-randomised trial investigating the impact of asthma education on specific disease understanding, health literacy and therapy outcome in childhood
BMJ open
childhood mental health problems common impairing become chronic left untreated children reliable reporters emotional behavioral health caregivers often unintentionally overreport child symptoms making assessment challenging objective physiological behavioral measures emotional behavioral health emerging however methods typically require specialized equipment expertise data sensor engineering administer analyze address challenge developed champ childhood assessment management digital phenotypes system includes mobile application collecting movement audio data battery mood induction tasks opensource platform extracting digital biomarkers proof principle present champ system data 101 children 48 years old without diagnosed mental health disorders machine learning models trained data detect presence specific disorders 7073 balanced accuracy similar results clinical thresholds established parentreport measures 6382 balanced accuracy features favored model architectures described using shapley additive explanations shap canonical correlation analysis reveals moderate strong associations predictors disorder associated symptom severity r 5183 opensource champ system provides clinicallyrelevant digital biomarkers may later complement parentreport measures emotional behavioral health detecting kids underlying mental health conditions lowers barrier entry researchers interested exploring digital phenotyping childhood mental health