Jane M. Simoni|John S. Wiebe|John A Sauceda|David Huh|Giselle Pinochet Sánchez|Virginia Longoria|C. Andres Bedoya|Steven A. Safren
A Preliminary RCT of CBT-AD for Adherence and Depression Among HIV-Positive Latinos on the U.S.-Mexico Border: The Nuevo Día Study
University of Washington|The University of Texas at El Paso|The University of Texas at El Paso|University of Washington|The University of Texas at El Paso|The University of Texas at El Paso|Massachusetts General Hospital|Harvard University|Massachusetts General Hospital|Harvard University
conducted preliminary rct among 40 hivpositive latinos mexican descent usmexico border indicated imperfect adherence depressive symptomatology participants randomly assigned culturally adapted cognitivebehavioral therapy adherence depression alarmed pillbox usual care outcomes depressive symptoms selfreport blind clinician ratings adherence selfreport electronic pillbox biological markers intervention delivered english spanish proved feasible acceptable generalized estimating equations intenttotreat analyses showed effects moderate large size maintenance time example intervention vs control participants demonstrated postintervention greater drop bdi scores 364 p 005 greater adherence according electronic pillbox 378 p 003 biological markers indicated relative improvement cd4 count vl promising results suggest larger trial determine efficacy warranted