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Mobile App Use among Persons with Fibromyalgia: A Cross-sectional Survey
The journal of pain
appraisal treatment outcomes integrative medicine challenge due gap concepts western medicine wm disease traditional chinese medicine tcm syndrome study presents approach appraisal integrative medicine based targeted metabolomics use nonalcoholic fatty liver disease spleen deficiency syndrome test case patientreported outcome pro scale developed based literature review delphi consensus survey reliability validity test quantitatively evaluate spleen deficiency syndrome metabonomic foundation treatment nonalcoholic fatty liver disease spleen deficiency syndrome identified via longitudinal interventional trial targeted metabolomics finally integrated appraisal model established identifying metabolites responded treatment wm disease tcm syndrome positive outcomes using aspects metabonomic foundation independent variables ten symptoms signs included spleen deficiency pro scale internal reliability content validity discriminative validity structural validity scale qualified based treatment responses treatments wm disease homeostasis model assessment insulin resistance tcm syndrome spleen deficiency pro scale score previous randomized controlled trial two cohorts comprised 30 participants established targeted metabolomics detection twentyfive metabolites found involved successful treatment outcomes wm tcm following quantitative comparison multivariate analysis finally model integrated appraisal system exploratively established using binary logistic regression included 9 core metabolites prediction probability 833 study presented new comprehensive research route integrative appraisal treatment outcomes wm disease tcm syndrome critical research techniques used research included development tcm syndrome assessment tool longitudinal interventional trial verified tcm treatment identification homogeneous metabolites statistical modeling