Muhammad Aaqib Shamim, Bijaya K Padhi, Prakasini Satapathy, Abdelmonem Siddiq, Subhanwita Manna, Arun K Aggarwal, Tareq Al-Ahdal, Jagdish Khubchandani, Andrés F Henao-Martinez, Ranjit Sah
Parents' expectation of antibiotic prescriptions for respiratory infections in children: a systematic review and meta-analysis
Therapeutic advances in infectious disease
acute chest syndrome acs common complication among pediatric inpatients sickle cell disease vasoocclusive crisis voc however little known factors associated acs complication present study assessed epidemiological features children hospitalized voc ascertained factors associated acs complication hospital discharge records patients voc aged 20 years obtained years 2003 2006 2009 2012 kids inpatient database data weighted estimate annual hospitalization rates respect gender raceethnicity united states multivariable logistic regression conducted ascertain factors associated acs complication adjusting patient hospital characteristics total annual hospitalizations voc increased 22511 2003 24292 2012 multivariable logistic regression analysis showed children aged 59 years 259 times higher odds acs children aged 1519 years 95 confidence interval ci 232288 comorbidity asthma odds ratio 142 95 ci 131154 obstructive sleep apnea 170 95 ci 131220 associated acs development acs also associated male gender summer fall seasons reported nationwide estimates annual hospitalization rate childhood voc united states demonstrated major risk factors associated acs complication vigilance needed acs complications highrisk voc admissions