Victoria Bray|Haryana M. Dhillon|Melanie L. Bell|Michael Kabourakis|Mallorie H. Fiero|Desmond Yip|Frances Boyle|Melanie A. Price|Janette Vardy
Evaluation of a Web-Based Cognitive Rehabilitation Program in Cancer Survivors Reporting Cognitive Symptoms After Chemotherapy
Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney|Liverpool Hospital|University of Sydney
purpose cognitive impairment reported frequently cancer survivors proven treatments evaluated cognitive rehabilitation program insight compared standard care cancer survivors selfreporting cognitive symptoms patients methods recruited adult cancer survivors primary malignancy excluding central nervous system malignancies completed three cycles adjuvant chemotherapy previous 6 60 months reported persistent cognitive symptoms participants received 30minute telephone consultation randomly assigned 15week homebased intervention standard care primary outcome selfreported cognitive function functional assessment cancer therapy cognitive function factcog perceived cognitive impairment pci subscale difference groups intervention t2 6 months later t3 results total 242 participants randomly assigned median age 53 years 95 female primary outcome difference factcog pci significant less pci intervention group t2 p 001 difference sustained t3 p 001 t2 significant difference factcog subscales favoring intervention neuropsychological results significantly different groups t2 t3 significantly lower levels anxietydepression fatigue intervention group t2 significant improvements stress intervention group time points significant difference quality life groups t2 intervention group better quality life t3 conclusion intervention insight led improvements cognitive symptoms compared standard care knowledge first large randomized controlled trial showing improvement selfreported cognitive function cancer survivors indicating intervention feasible treatment