Paul C. Schroy|Alison Coe|Clara A. Chen|Michael J. O?Brien|Timothy Heeren
Prevalence of Advanced Colorectal Neoplasia in White and Black Patients Undergoing Screening Colonoscopy in a Safety-Net Hospital
chinese translation background black persons likely white persons diagnosed colorectal cancer die extent genetic biological factors versus disparities screening rates explain variance remains controversial objective define prevalence location presymptomatic advanced colorectal neoplasia acn among white black persons undergoing screening colonoscopy controlling epidemiologic risk factors design crosssectional survey 22 march 2005 31 january 2012 setting urban openaccess academic safetynet hospital massachusetts participants asymptomatic averagerisk white n 1172 black n 1681 persons aged 50 79 years undergoing screening colonoscopy measurements adjusted prevalence location acn defined tubular adenoma 10 mm size adenoma villous features highgrade dysplasia dysplastic serrated lesion invasive cancer results prevalence acn higher among white patients black patients 68 vs 50 p 0039 varied sex white vs black men 93 vs 57 white vs black women 35 vs 43 interaction p 0034 controlling many risk factors black men 41 less likely white men adjusted odds ratio aor 059 95 ci 039 089 acn statistically significant difference seen women aor 132 ci 073 240 black patients acn higher percentage proximal disease 52 vs 39 adjustment age sex p 0055 limitation singleinstitution study inadequate statistical power subgroup analyses recall bias conclusion black men less likely white men acn screening colonoscopy safetynet health care setting disparities access screening differential exposure modifiable risk factors rather genetic biological factors may largely responsible higher incidence crc among black men genetic biological factors may explain predilection proximal disease primary funding source national cancer institute