Aladeen Alloubani, Majeda Al-Ruzzieh, Nour Khawaja, Laila Akhu-Zaheya
Genomic Literacy among Nurses in Jordan: A Population-based Study
Journal of cancer education : the official journal of the American Association for Cancer Education
temporal lobe epilepsy tle prevalent form drugresistant epilepsy concurrent cognitive impairment prevention earlier diagnosis personalized management cognitive deficits tle require understanding underlying structural functional brain ialterations study evaluated performance tle patients different cognitive domains based structural brain lesions study 69 refractory tle patients underwent magnetic resonance imaging mri epilepsy protocol several neuropsychological tests consisting wechsler adult intelligence scalerevised reyosterrieth complex figure test verbal fluency test digit span test spatial span test wechsler memory scaleiii design fluency test rey visual design learning test auditoryverbal learning test trail making test mri findings classified following groups focal cortical dysplasia gliosis atrophy mesial temporal sclerosis mts tumor vascular malformation lesions normal results neuropsychological tests compared mri groups using generalized linear model gamma distribution log link patients mts showed better performance general intellectual functioning working memory attentional span auditoryverbal learning compared patients nonmts mri lesions atrophy focal cortical dysplasia largest differences mts cognitive performance refractory tle patients varies concerning structural brain alterations neuroimaging studies tle lead prevention accurate management cognitive decline clinical settings cognitive status temporal lobe epilepsy tle varies concerning structural brain alterationspatients mesial temporal sclerosis mts show better cognitive performance nonmts lesionsamong nonmts findings patients atrophy severe cognitive deficits temporal lobe epilepsy tle common form epilepsy respond antiseizure drugs needs surgery brain lesions one important issues tle patients cognitive impairment cognition refers mental processes thinking understanding perception environment attention memory learning language etc prevention earlier diagnosis treatment cognitive deficits tle patients need understanding brain changes study evaluated cognition tle patients detail based brain lesions study 69 drugresistant tle patients undergone brain magnetic resonance imaging mri several neuropsychological tests assess cognition consisting wechsler adult intelligence scalerevised reyosterrieth complex figure test verbal fluency test digit span test spatial span test wechsler memory scaleiii design fluency test rey visual design learning test auditoryverbal learning test trail making test mri findings classified following groups based type brain lesion expert focal cortical dysplasia gliosis atrophy mesial temporal sclerosis mts tumor vascular malformation lesions normal results neuropsychological tests compared mri groups using appropriate statistical methods patients mts common lesion tle showed better results compared patients lesions mts intelligence memory attention learning tests patients atrophy focal cortical dysplasia largest differences mts results suggest cognitive performance drugresistant tle patients different based structural brain changes imaging particular brain mri available technique clinic assessment epilepsy brain imaging studies lead prevention better management cognitive decline tle