Michael S. Kramer|Lidia Matush|Irina Vanilovich|Robert W. Platt|Natalia Bogdanovich|Zinaida Sevkovskaya|Irina Dzikovich|Gyorgy Shishko|Jean?Paul Collet|Richard M. Martin|George Davey Smith|Matthew W. Gillman|Beverley Chalmers|Ellen Hodnett|Stanley H. Shapiro
A Randomized Breast-feeding Promotion Intervention Did Not Reduce Child Obesity in Belarus
McGill University|McGill University|McGill University|University of Bristol|University of Bristol|Harvard Pilgrim Health Care|Harvard University|University of Ottawa|University of Toronto|McGill University
evidence breastfeeding protects obesity based observational studies potential confounding selection bias article summarizes previously published study assessed whether intervention designed promote exclusive prolonged breastfeeding affects childrens height weight adiposity blood pressure bp age 65 promotion breastfeeding intervention trial probit clusterrandomized trial breastfeeding promotion intervention based whounicef babyfriendly hospital initiative total 17046 healthy breastfed infants enrolled 31 belarussian maternity hospitals affiliated clinics 13889 815 followed 65 duplicate measurements height weight waist circumference triceps subscapular skinfold thicknesses systolic diastolic bp analysis based intention treat statistical adjustment clustering within hospitalsclinics permit inferences individual level experimental intervention led large increase exclusive breastfeeding 3 mo 433 vs 64 p 0001 significantly higher prevalence breastfeeding throughout infancy significant intervention effects observed height bmi adiposity measures bp breastfeeding promotion intervention resulted substantial increases duration exclusivity breastfeeding yet reduce measures adiposity age 65 previous reports protective effects obesity may reflect uncontrolled bias caused confounding selection