Ebele M. Umeukeje|Joseph R. Merighi|Teri Browne|Jacquelyn N. Victoroff|Kausik Umanath|Julia Lewis|T. Alp ?kizler|Kenneth A. Wallston|Kerri L. Cavanaugh
Self-Motivation Is Associated With Phosphorus Control in End-Stage Renal Disease
Vanderbilt Health|Vanderbilt University|University of Minnesota|University of South Carolina|University of Washington|Henry Ford Hospital|Vanderbilt Health|Vanderbilt University|Vanderbilt Health|Vanderbilt University|Vanderbilt University|Vanderbilt Health|Vanderbilt University
hyperphosphatemia common endstage renal disease associates mortality phosphate binders reduce serum phosphorus levels however adherence often poor pilot study aims assess patients selfmotivation adhere phosphate binders association phosphorus control potential differences racecross sectional design subjects enrolled one academic medical center dialysis practice july november 2012 selfmotivation adhere phosphate binders assessed autonomous regulation ar scale range 17 selfreported medication adherence morisky medication adherence scale linear regression models adjusting age sex health literacy medication adherence applied determine associations serum phosphorus level including evidence interaction raceamong 100 participants mean age 51 years 15 years 53 male 72 nonwhite 89 received hemodialysis mean serum phosphorus level 57 16 mgdl half 57 reported maximum ar score 7 higher ar scores noted reporting better health overall p 001 higher health literacy p 01 ar score correlated better medication adherence r 022 p 02 medication adherence negatively associated serum phosphorus r 040 p 001 subgroup analysis among nonwhites higher ar scores correlated lower serum phosphorus high vs lower ar score 555 15 vs 696 22 p 01 associations ar score 95 confidence interval 037 073 001 p 04 medication adherence 95 confidence interval 025 042 007 p 01 serum phosphorus persisted adjusted analysesselfmotivation associated phosphate binder adherence phosphorus control differed race additional research needed determine personalized culturally sensitive strategies understand overcome motivational barriers may optimize mineral bone health endstage renal disease