Jie Bai
Humanistic Spirit Training of Medical Students Based on Multisource Medical Data Fusion
Computational and mathematical methods in medicine
currently prospective studies evaluating longterm outcomes nonsurgical root canal treatments beyond 5 years terms treatment success tooth preservation identifying factors predictive treatment outcome aim present work therefore fill gap assessing outcomes time identifying predictive variables based systematic data collection 25year period data concerning treatments n 2500 systematically collected since 1990 information recorded among clinical technical radiographic patientrelated characteristics ie approximately 150 variables treatment data analysed regarding treatment success tooth preservation multivariable cox proportional hazards model survival curves generated statistical significance level set 00125 total 564 treatments could followed time 025 years mean 65 years median 5 years survival probability decreased almost linearly treatment success 85 5 years 60 20 years tooth preservation 90 5 years 50 20 years variables significantly associated treatment failure preoperative pain hazard ratiohr 156 95 ci 123197 persistent pain hr 263 95 ci 144480 good operator rating treatment prognosis hr 046 95 ci 036058 size periapical bone radiolucency hr 188 95 ci 167211 tooth type p 0006 tooth extraction combined endodonticperiodontal lesion hr 337 95 ci 188605 preexisting complication treatment hr 167 95 ci 126221 good operator rating treatment prognosis hr 045 95 ci 033060 clinical failure root canal treatment hr 278 95 ci 198389 tooth type p 0012 root canal treatment success tooth preservation arch static outcomes evolve time among substantial set potential predictors small proportion significantly predictive treatment success tooth preservation disease patient characteristics technical aspects except preexisting complications observations challenge importance frequently given byzantine considerations related numerous technical details endodontic procedures opposed general concepts good clinical practice