Victoria Westbrook, Duane T Wegener, Mark W Susmann
Mechanisms in continued influence: The impact of misinformation corrections on source perceptions
Memory & cognition
parkinsons disease pd neurodegenerative progressive disease impacts nerve cells brain varies person person exact cause pd still unknown diagnosis pd include specific objective test certainty although deep learning made great progress medical neuroimaging analysis methods susceptible biases present neuroimaging datasets innovative decorrelated deep learning technique introduced mitigate class bias scanner bias simultaneously focusing finding distinguishing characteristics restingstate functional mri rsfmri data assists recognizing pd good accuracy decorrelation function reduces nonlinear correlation features bias order learn biasinvariant features publicly available parkinsons progression markers initiative ppmi dataset referred singlescanner imbalanced dataset study used validate method imbalanced dataset problem affects performance deep learning framework overfitting majority class resolve problem propose new decorrelated convolutional neural network dccnn framework applying decorrelationbased optimization convolutional neural networks cnns analysis evaluation metrics comparisons shows integrating decorrelation function boosts performance pd recognition removing class bias specifically dccnn models perform significantly better existing traditional approaches tackle imbalance problem finally framework extended create scannerinvariant features without significantly impacting performance model obtained dataset multiscanner dataset leads scanner bias due differences acquisition protocols scanners multiscanner dataset combination two publicly available datasets namely ppmi ftldnithe frontotemporal lobar degeneration neuroimaging initiative nifd dataset results tdistributed stochastic neighbor embedding tsne scanner classification accuracy proposed feature extractiondccnn fedccnn model validated effective removal scanner bias method achieves average accuracy 7780 multiscanner dataset differentiating pd healthy control superior dccnn model trained singlescanner imbalanced dataset