Colby Lewis V, Jack Huebner, George Hripcsak, Maya Sabatello
Underrepresentation of blind and deaf participants in the All of Us Research Program
Nature medicine
case underreporting coronavirus disease 2019 covid19 pandemic major challenge planning evaluation public health responses school children often considered less vulnerable population underreporting rates may particularly high january 2022 canadian province newfoundland labrador nl experiencing omicron variant outbreak ba1ba2 subvariants public health officials recommended returning students complete two rapid antigen tests rats performed three days apart estimate prevalence severe acute respiratory syndrome coronavirus 2 sarscov2 asked parents guardians report results rats completed k12 students approximately 59000 students using online survey comparing survey responses number cases tests reported nl testing system found one every 43 95 ci 3153 positive households captured provincial case count 51 positivity estimated rat results 12 positivity reported provincial testing system positive test results 629 95 ci 443830 reported elementary school students remaining 371 95 ci 227529 reported junior high high school students asymptomatic infections 598 positive cases given low survey participation rate 35 results may suffer sample selection biases interpreted caution underreporting ratio consistent ratios calculated serology data provides insights infection prevalence asymptomatic infections school children currently understudied population