Sunil Sazawal|Robert E. Black
Meta-analysis of intervention trials on case-management of pneumonia in community settings
Johns Hopkins University|Johns Hopkins University
appraise effectiveness pneumonia casemanagement strategy improving child survival done metaanalysis six published intervention trials results seventh published study two unpublished studies also reviewedthe six published studies satisfied criteria methodological soundness reduction mortality rate control group minus intervention group estimated study studies together total infant mortality overall reduction 159 95 confidence interval 106211 deaths per 1000 livebirths infant mortality due acute lower respiratory infection reduced 107 48167 deaths1000 livebirths mortality among children 5 years decreased 36 deaths1000 livebirths pooled estimates relative risk consistent 20 reduction infant mortality 25 reduction under5 mortality clear association across studies effect pneumonia casemanagement extent cointerventions immunisation oral rehydration therapythe consistency findings studies despite differences design methods shows casemanagement strategy substantial effect infant under5 mortality least settings infant mortality rates 901000 livebirths important find efficient ways implementing strategy integrating primary health care