Vinh?Kim Nguyen|Zoë R Greenwald|Helen Trottier|Martha Cadieux|Alexandre Goyette|Mariève Beauchemin|Louise Charest|Danièle Longpré|Stéphane Lavoie|Hermione Gbego Tossa|Réjean Thomas
Incidence of sexually transmitted infections before and after preexposure prophylaxis for HIV
Graduate Institute of International and Development Studies|CHI Health Immanuel|Université de Montréal|Centre Hospitalier Universitaire Sainte-Justine|CHI Health Immanuel|CHI Health Immanuel|CHI Health Immanuel|CHI Health Immanuel|CHI Health Immanuel|CHI Health Immanuel|Université de Montréal|CHI Health Immanuel|CHI Health Immanuel
use preexposure prophylaxis prep hiv raises concerns sexually transmitted infection sti incidence decreased condom use among msm study examines whether prep associated stis 12 months following prep prescription relative 12 months prior prep sti rates higher among prep users relative individuals receiving postexposure prophylaxis pepretrospective cohort study including prep users 12 months followup prep prescription individuals receiving pep 2010 2015 clinique lactuel montral canadaincidence chlamydia gonorrhoea syphilis hepatitis c virus 12 months compared prep prep versus pep users using poisson models generate incidence rate ratios irrs 95 confidence intervals cis adjusted irrs airrs controlling frequency stiscreening visits models comparing prep pep users adjusted age educationone hundred nine prep 86 pep users included increased rates stis observed 12 months prep relative 12 months prior irr 172 ci 122241 airr 139 ci 098196 prep users also higher sti risk relative pep users irr 218 ci 146324 airr 176 ci 114271increased rates stis among individuals initiation prep may suggest greater risk behaviours first year prep studies needed measure longterm trends sti acquisition following prep initiation