Andrea B Bontrager Yoder, Janice L Liebhart, Daniel J McCarty, Amy Meinen, Dale Schoeller, Camilla Vargas, Tara LaRowe
Farm to elementary school programming increases access to fruits and vegetables and increases their consumption among those with low intake
Journal of nutrition education and behavior
skin sensitization increasingly becoming significant concern development drugs cosmetics due consumer safety occupational health problems silico methods emerged alternatives traditional vivo animal testing due ethical economic considerations study machine learning methods used build quantitative structureactivity relationship qsar models five skin sensitization data sets gpmt llna dpra keratinosens hclat achieving effective predictive accuracies correct classification rates 06880764 test sets address complex mechanisms human skin sensitization dempstershafer theory applied merge multiple qsar models resulting evidencebased integrated decision model various evidence combinations combination rules explored selfdefined q3 rule showing superior balance combination evidence gpmt keratinosens hclat achieved correct classification rate ccr 0880 coverage 0893 maintaining competitiveness combinations additionally shapley additive explanations shap method used interpret important features substructures related skin sensitization comparative analysis external human test set demonstrated superior performance proposed method finally enhance accessibility workflow implemented userfriendly software named hskinsensds