Claude A. Mellins|Jennifer Havens|Cheryl J. McDonnell|Carolyn Lichtenstein|Karina K. Uldall|Margaret A. Chesney|E. Karina Santamaria|J. Simon Bell
Adherence to antiretroviral medications and medical care in HIV-infected adults diagnosed with mental and substance abuse disorders
New York Psychoanalytic Society and Institute|Columbia University|New York University|University School|James Bell Associates (United States)|McDonald's (United States)|University of Washington|San Francisco AIDS Foundation|New York Psychoanalytic Society and Institute|Columbia University|James Bell Associates (United States)
abstract paper examines factors associated adherence antiretroviral medications arvs hivinfected population high risk nonadherence individuals living psychiatric substance abuse disorders data examined baseline interviews multisite cohort intervention study 1138 hivinfected adults psychiatric substance abuse disorder based structured psychiatric research interview using dsmiv criteria baseline interview documented mental illness substance use past year mental illness substance abuse severity demographics service utilization past three months general health hivrelated conditions selfreported spirituality selfreported arv medication use among participants 62 prescribed arvs baseline n 542 45 arvs reported skipping medications past three days reports nonadherence significantly associated detectable viral load p01 factors associated nonadherence current drug alcohol abuse increased psychological distress less attendance medical appointments nonadherence psychiatric medications lower selfreported spirituality increased psychological distress significantly associated nonadherence independent substance abuse p05 data suggest mental illness substance use must addressed hivinfected adults living comorbid illnesses improve adherence arvs