David Price|Brooke Harrow|Mark Small|James Pike|Victoria Higgins
Establishing the relationship of inhaler satisfaction, treatment adherence, and patient outcomes: a prospective, real-world, cross-sectional survey of US adult asthma patients and physicians
University of Aberdeen|Adelphi Group (United Kingdom)|Adelphi Group (United Kingdom)|Adelphi Group (United Kingdom)
inhaled asthma medications mainstay treatment chronic asthma however nonadherence rates longterm inhaler therapy among adults estimated exceed 50 nonadherence associated unfavorable clinical outcomes diminished quality life research suggests adherence associated patients satisfaction treatment regimen factors concomitant allergic rhinitis tobacco usethis prospective crosssectional survey physicians patients evaluated relationship patient satisfaction attributes inhaler devices treatment adherence clinical outcomes primary care specialist physicians completed physicianreported patient record form patients confirmed asthma diagnosis patients physicianreported form completed invited complete patientreported form surveys collected information demographics symptoms exacerbation history treatment smoking status comorbidities type inhaler device treatment adherence patients also indicated degree satisfied attributes currently prescribed inhaler devices partial least squares path modeling quantified relationships latent variables clinical outcomesa total 243 patients included analysis 41 poorly controlled asthma favorable clinical outcomes significantly associated greater patient satisfaction drug delivery p 0002 higher medication adherence p 0049 history tobacco use p 0001 absence comorbid allergic rhinitis p 0005 attributes associated device satisfaction included patient perceptions consistency amount drug delivery lungs ease use feedback number remaining doseshigher patient satisfaction asthma drug delivery inhaler device significant predictor favorable clinical outcomes allergic rhinitis smoking history negatively associated optimal control asthma findings provide clinicians opportunities improve patients clinical outcomes tailoring choice inhaler device therapy providing education correct way use device ensure optimal outcomes patients likely benefit medical therapy manage comorbid allergic rhinitis smoking cessation interventions patients unable stop smoking may require alternative medical therapies improve clinical outcomes