Shiu F Wong, Jessica R Grisham
Inverse reasoning processes in obsessive-compulsive disorder
Journal of anxiety disorders
patients diagnosed dominant intraprostatic lesions dil may need radiation doses 80 gy dosepainting contours dpc useful technique helps patients dosepainting approach need evaluated evaluate dcp technique case boosting dils radiobiological parameters tumor control probability tcp normal tissue complication probability ntcp via petct images traced 68gapsma analytical study 68gapsma petct images obtained patients dils delineated using fuzzy cmean fcm algorithm thresholding methods protocol therapy included two phases first phase ph1 total dose 72 gy 36 fractions delivered planning target volume ptv1 seconds phase consisted application variable doses ptv2 moreover two concepts also considered calculate tcp using zaiderminerbo model lowest volume dils belonged dil1 extracted fcm method according dosevolume parameters rectum bladder increase ptv dose higher 92 gy amounts rectum bladder doses increased difference tcps dils doses higher 86 gy 100 gy ordinary high clone density respectively consequently dosepainting approach dils extracted fcm method via petct images reduce total dose prostate radiation 100 tumor control less normal tissue complications