Kathryn E. Callahan|James Lovato|Michael E. Miller|Douglas Easterling|Beth E. Snitz|Jeff D. Williamson
Associations Between Mild Cognitive Impairment and Hospitalization and Readmission
Wake Forest University|Wake Forest University|Wake Forest University|Wake Forest University|University of Pittsburgh|Wake Forest University
determine whether older adults mild cognitive impairment mci condition previously explored risk factor hospitalizations 30day readmissions normal cognitionpost hoc analysis prospectively gathered data incident hospitalization readmission ginkgo evaluation memory study gems randomized doubleblind placebocontrolled trial designed assess effect ginkgo biloba incidence dementiagems conducted five academic medical centers united statescommunitydwelling adults aged 75 older normal cognition n 2314 mci n 428 baseline cognitive testing n 2742index hospitalization 30day hospital readmission adjusted age sex race education clinic site trial assignment status comorbidities number prescription medications living identified proxymci associated 17 greater risk index hospitalization normal cognition adjusted hazard ratio ahr 117 95 confidence interval ci 102134 participants lived proxy mci associated 39 greater risk index hospitalization ahr 139 95 ci 117166 baseline mci associated greater odds 30day hospital readmission adjusted odds ratio 090 95 ci 060136mci may represent target condition healthcare providers coordinate support services effort reduce hospitalization subsequent disability