Johnny Singh, Andreas Stensvold, Martin Turzer, Ellen Karine Grov
Anticancer therapy at end-of-life: A retrospective cohort study
Acta oncologica (Stockholm, Sweden)
fluorescence molecular endoscopy fme emerging redflag technique potential deliver earlier faster personalized detection disease gastrointestinal tract including cancer gain insights novel drug distribution dose finding response prediction however date performance fme systems assessed mainly endoscopists procedure leading arbitrary potentially biased heavily subjective assessment approach significantly affects repeatability procedures interpretation comparison acquired data representing major bottleneck towards clinical translation technology herein propose robust methodology fme performance assessment quality control based novel multiparametric rigid standard standard enables characterization fme systems sensitivity single acquisition performance comparison multiple systems first time quality control system function time number usages show photostability standard experimentally demonstrate used characterize performance fme system moreover showcase standard employed quality control system study find use composite fluorescence standards endoscopic procedures ensure fme system meets performance criteria components prone performance degradation replaced time avoiding disruption clinical endoscopy logistics help overcome major barrier translation fme clinics