James W.F. Catto|Amy Downing|S. F. Mason|Penny Wright|Kate Absolom|Sarah Bottomley|Luke Hounsome|Syed A. Hussain|Mohini Varughese|Caroline Raw|Phil Kelly|Adam Glaser
Quality of Life After Bladder Cancer: A Cross-sectional Survey of Patient-reported Outcomes
University of Sheffield|Sheffield Teaching Hospitals NHS Foundation Trust|University of Leeds|University of Leeds|University of Leeds|University of Leeds|University of Sheffield|National Cancer Registration Service|Public Health England|Weston Park Cancer Centre|University of Sheffield|Musgrove Park Hospital|Leeds Teaching Hospitals NHS Trust|University of Leeds
little known healthrelated quality life hrqol following treatment bladder cancer bcto determine undertook crosssectional survey covering 10 english populationparticipants 110 yr diagnosis identified national cancer registration dataa postal survey administered containing generic hrqol bcspecific outcome measures findings compared general population pelvic cancer patientsgeneric hrqol measured using fivelevel eq5d eq5d5l european organization research treatment cancer quality life questionnaire eortc qlqc30 bcspecific outcomes derived eortc qlqblm30 eortc qlqnmibc24a total 1796 surveys completed response rate 55 including 868 48 patients nonmuscleinvasive bc 893 50 patients received radiotherapy radical cystectomy 35 19 patients treatment unknown 69 participants reported least one problem eq5d dimension agesexadjusted generic hrqol outcomes similar across stages treatment groups whilst problems increased age problems one eq5d dimensions 65 yr 67 95 confidence interval ci 6174 vs 85 yr 84 95 ci 8189 p 0016 longterm conditions conditions 53 95 ci 4858 vs four conditions 94 95 ci 9097 p 0001 sexual problems reported commonly men increasing younger age radical treatment younger participants 65 yr reported financial difficulties mean score 20 95 ci 1625 aged 85 yr 68 4592 p 0001 hrqol bc patients comparison males problems one eq5d dimensions 69 95 ci 6672 significantly worse found colorectal prostate cancers general population 51 95 ci 4853 p 005hrqol following bc appears relatively independent disease stage treatment multimodal care issues reported sexual function financial toxicity hrqol bc worse pelvic cancerspatients living bladder cancer often reduced quality life may worse common pelvic cancer patients age illnesses appear important determining quality life treatments received many men complain sexual problems younger patients financial worries