Hailay Gebrekidan, Mussie Alemayehu, Gurmesa Tura Debelew
Individual and community level factors associated with modern contraceptive utilization among women in Ethiopia: Multilevel modeling analysis
PloS one
liberal use blood cultures emergency departments eds leads low yields high numbers falsepositive results falsepositive contaminated cultures associated prolonged hospital stays increased antibiotic usage even higher hospital mortality rates trial aims investigate whether recently developed validated machine learning model predicting blood culture outcomes safely effectively guide clinicians withholding unnecessary blood culture analysis randomised controlled noninferiority trial comparing current practice machine learningguided approach primary objective determine whether machine learning based approach noninferior standard practice based 30day mortality secondary outcomes include hospital lengthof stay hospital admission rates outcomes include model performance antibiotic usage participants recruited eds multiple hospitals netherlands total 7584 participants included possible participants receive verbal information paper information brochure regarding trial given least 1 hour consideration time providing informed consent research results published peerreviewed journals study approved amsterdam university medical centers local medical ethics review committee 220567 study conducted concordance principles declaration helsinki accordance medical research involving human subjects act general data privacy regulation medical device regulation nct06163781