Samuel C Willimon, Marjorie M Johnson, Mackenzie M Herzog, Michael T Busch
Time to Return to School After 10 Common Orthopaedic Surgeries Among Children and Adolescents
Journal of pediatric orthopedics
valid reliable patientreported outcome measures vital assessing disease impact responsiveness healthcare costeffectiveness interventions recent review questioned ability existing measures assess hypoglycaemiarelated impacts healthrelated quality life people diabetes mixedmethods project designed produce novel healthrelated quality life patientreported outcome measure hypoglycaemia hyporesolve qol three studies conducted people diabetes experience hypoglycaemia stage 1 comprehensive healthrelated quality life framework hypoglycaemia elicited semistructured interviews n31 stage 2 content validity acceptability draft measure content tested via three waves cognitive debriefing interviews n70 people diabetes n14 clinicians stage 3 revised measure content administered alongside existing generic diabetesrelated measures large crosssectional observational survey assess psychometric performance n1246 final measure developed using multiple evidence sources incorporating stakeholder engagement novel conceptual model hypoglycaemiarelated healthrelated quality life generated featuring 19 themes organised physical social psychological aspects draft version 76 items final 14item measure produced satisfactory structural 247227 df74 p0001 comparative fit index 0943 root mean square error approximation 0069 convergent validity related constructs r046059 internal consistency 091 testretest reliability intraclass correlation coefficient 087 hyporesolve qol rigorously developed patientreported outcome measure assessing healthrelated quality life impacts hypoglycaemia hyporesolve qol demonstrable validity reliability value use clinical decisionmaking clinical trial endpoint data generated analysed study included published article online supplementary files httpsdoiorg1015131shef 23295284v2