J Ramirez Rivera, R Rodríguez, Y Otero Igaravidez
Attitudes toward euthanasia, assisted suicide and termination of life-sustaining treatment of Puerto Rican medical students, medical residents, and faculty
Boletin de la Asociacion Medica de Puerto Rico
reference intervals vital part information supplied clinical laboratories support interpretation numerical pathology results produced clinical chemistry hematology laboratories traditional method establishing reference intervals known direct approach based collecting samples members preselected reference population making measurements determining intervals alternative approach perform analysis results generated part routine pathology testing using appropriate statistical techniques determine reference intervals known indirect approach paper working group international federation clinical chemistry ifcc committee reference intervals decision limits cridl aims summarize current thinking indirect approaches reference intervals indirect approach major potential advantages compared direct methods processes faster cheaper involve patient inconvenience discomfort risks associated generating new patient health information indirect methods also use preanalytical analytical techniques used patient management provide large numbers assessment limitations indirect methods include possible effects diseased subpopulations derived interval ifcc cridl aims encourage use indirect methods establish verify reference intervals promote publication intervals clear explanation process used also support development improved statistical techniques studies