Sabine Heim|Carsten Eulitz|Thomas Elbert
Altered hemispheric asymmetry of auditory P100m in dyslexia
Rutgers, The State University of New Jersey|University of Konstanz|University of Konstanz|University of Konstanz
abstract various studies deviances hemispheric laterality organization perisylvian region dyslexia suggested although associated impaired language functioning clinical significance atypical cerebral lateralization remains unclear present study examined interhemispheric source differences magnetic responses german synthetic syllable ba auditory cortex 14 dyslexic children 12 normally literate controls aged 815 years subjects two main deflections p100m n260m evident responses hemisphere control group right p100m dipole located anterior corresponding dipole left hemisphere dyslexic group displayed rather symmetrical source configuration hemispheres symmetry reflected deviance right perisylvian region dyslexic subjects p100m generated 1 cm posterior response controls deviation also obvious relative source location later component n260m systematically differ participant groups results suggest altered hemispheric asymmetry reflects atypical organization right hemisphere children adolescents dyslexia