Olatunji Adetokunboh|Olalekan A. Uthman|Charles Shey Wiysonge
Effect of maternal HIV status on vaccination coverage among sub-Saharan African children: A socio-ecological analysis
South African Medical Research Council|Western Cape Department of Health|Stellenbosch University|South African Medical Research Council|Western Cape Department of Health|Stellenbosch University|University of Warwick|South African Medical Research Council|Western Cape Department of Health|Stellenbosch University|University of Cape Town
investigated relationship maternal hiv status uptake full series three doses diphtheriatetanuspertussis containing vaccines dtp3 subsaharan african children used data obtained demographic health surveys conducted subsaharan africa conducted metaanalysis calculated pooled odds ratios association maternal hiv status dtp3 vaccination status country total 4187 5537 children women living hiv received dtp3 756 compared 71290 113513 628 children hiv negative women national dtp3 coverage among children hivpositive women varied 24 96 among children hiv negative women 26 92 overall pooled result showed significant difference dtp3 coverage two groups 105 95 confidence interval 091 122 statistically significant heterogeneity chi 2 9163 p 0000 i2 716 significant association dtp3 coverage maternal hiv status subsaharan africa however dtp3 coverage hivexposed nonexposed children required target metaregression revealed significant association dtp3 coverage country characteristics eg hiv prevalence among women antiretroviral therapy coverage gross domestic product per capita human development index adult literacy rate subregion improved prevention mothertochild transmission services might contributed extent higher dtp3 vaccination coverage among hivexposed children also need address barriers impeding uptake vaccination among hivexposed nonexposed children