Manon van der Vlugt|Esmée J. Grobbee|Patrick M. Bossuyt|Evelien Bongers|Wolfert Spijker|Ernst J. Kuipers|Iris Lansdorp?Vogelaar|Marie?Louise Essink?Bot|Manon C.W. Spaander|Evelien Dekker
Adherence to colorectal cancer screening: four rounds of faecal immunochemical test-based screening
University of Amsterdam|Erasmus University Rotterdam|University of Amsterdam|Academic Medical Center|Dutch Expert Centre for Screening|Erasmus University Rotterdam|Erasmus University Rotterdam|Academic Medical Center|University of Amsterdam|Erasmus University Rotterdam|University of Amsterdam
effectiveness faecal immunochemical test fitbased screening programs highly dependent consistent participation multiple rounds evaluated adherence fit screening four rounds aimed identify determinants participation behaviour total 23 339 randomly selected asymptomatic persons aged 5074 years invited biennial fitbased colorectal cancer screening 2006 2014 invited every consecutive round except moved area passed upper age limit tested positive previous screening round reminder letter sent nonresponders calculated participation rates per round response rates reminder letter differences participation subgroups defined age sex socioeconomic status ses four rounds participation rates increased significantly 60 95 ci 6061 60 95 ci 5960 62 95 ci 6163 63 95 ci 6264 p trend0001 significantly higher participation rates women rounds p0001 17 312 invitees eligible least two rounds fit screening 12 455 72 participated least whereas 4857 28 never participated 8271 48 attended rounds eligible consistent participation associated older age female sex higher ses offering reminder letter initial invite first round increased uptake 12 subsequent screening rounds resulted additional uptake 10 four rounds pilot biennial fitscreening program observed consistently high increasing participation rate whereas sending reminders remain effective substantial proportion inconsistent participants suggests existence incidental barriers participation possible identified removed