Mary E Moya-Mendez, Steven Thornton, Kristen E Rhodin, Qimeng Gao, Harold J Leraas, Cory J Vatsaas
Longitudinal Integrated Clerkships and Undergraduate Surgical Education: A Scoping Review and Gap Analysis
Journal of surgical education
identification somatic mutations sms essential characterizing cancer genomes dnaseq prevalent method identifying sms rnaseq provides alternative strategy discover tumor mutations transcribed genome developed machine learning based pipeline discover sms based rnaseq data designated rnasms subsequently conducted pancancer analysis systematically identify rnasms 8000 tumors cancer genome atlas tcga way identified 105000 novel sms reported previous tcga studies novel sms significant clinical implications designing targeted therapy improved patient outcomes combined sms identified rnaseq dnaseq analyses depict updated mutational landscape across 32 cancer types new online sm atlas oncodb httpsoncodborg offers complete view gene mutations underline development progression various cancers