Zohreh Janbozorgi, Hasan Khalaji, Jalil Moradi
The effect of individual and paired Brailletonik exercises on balance and reaction time in children with intellectual disability
BMC sports science, medicine & rehabilitation
metastasisdirected therapy mdt stereotactic body radiotherapy sbrt emerging effective therapeutic option oligometastatic disease omd however lack phase iii data consensus guidelines toxicity concerns limit widespread use randomized controlled trials rcts routinely report hazard ratios hrs medians lack clear clinical robust interpretation restrictedmean survival time rmst duration time patient expected survive followup period providing robust interpretable alternative analyzed efficacy sbrt using rmst registered rcts ablative radiotherapy omd clinicaltrialsgov 2022 identified data reconstructed kaplanmeier curves hrs rmst differences estimated surrogate endpoints ses overall survival os six studies comprising 426 patients met inclusion criteria rmst differences ses ranged 46 months study iyengar et al 111 months sabrcomet rmst differences os sabrcomet gomez et al sindas studies 126 15 79 months respectively rmst demonstrates efficacy local treatment omd representing expected survival time method effectively communicates outcomes patients clinicians