Janice Lopez|K. Annunziata|Robert A. Bailey|Donald E. Morisky|Marcia F.T. Rupnow
Impact of hypoglycemia on patients with type 2 diabetes mellitus and their quality of life, work productivity, and medication adherence
Janssen (United States)|Kantar Health (United States)|Janssen (United States)|University of California, Los Angeles|Janssen (United States)
purpose study determine characteristics adults type 2 diabetes mellitus t2dm correlate greater risk hypoglycemia determine impact hypoglycemia healthrelated quality life work productivity medication adherence patient perspectivedata large webbased survey retrospectively analyzed adults diagnosis t2dm taking antihyperglycemic agents included analysis participants knowledge hypoglycemic history divided three groups experiencing recent hypoglycemia previous 3 months experiencing nonrecent hypoglycemia never experiencing hypoglycemiaof participants t2dm taking antihyperglycemic agents knowledgeable hypoglycemia history 557 ever experienced hypoglycemia 527 recent hypoglycemia compared never experienced hypoglycemia experienced hypoglycemia tended younger aware glycated hemoglobin hba1c levels higher hba1c levels higher body mass index higher charlson comorbidity index scores insulin sulfonylureas andor glucagonlike peptide1 agonists less adherent antihyperglycemic agents hypoglycemia interfered social activities caused missed work absenteeism impairment work presenteeism decreased overall work productivity compared patients never experienced hypoglycemia overall healthrelated quality life determined short form36 health questionnaire negatively impacted hypoglycemia physical mental summary scores significantly lower recent hypoglycemia nonrecent hypoglycemia groups compared never hypoglycemia grouphypoglycemia negatively impact many aspects life greater awareness risk developing hypoglycemia lead development measures eg patient physician education prevent future hypoglycemia episodes