Mağfiret Kaşıkçı, Zeynep Yıldırım
Interventions to improve ethical decision-making skills in nursing students: A systematic review
Nursing ethics
monitoring drug efficacy significant current concept companion diagnostics metastatic breast cancer trastuzumab drug targeting human epidermal growth factor receptor 2 her2 effective treatment metastatic breast cancer however patients develop resistance therapy therefore monitoring efficacy essential describe deep learningassisted monitoring trastuzumab efficacy based surfaceenhanced raman spectroscopy sers immunoassay her2overexpressing mouse urinary exosomes individual raman reporters bearing desired sers tag exosome capture substrate prepared sers immunoassay sers tag signals collected prepare deep learning training data using deep learning algorithm various complicated mixtures sers tags successfully quantified classified exosomal antigen levels five types cellderived exosomes determined using sersdeep learning analysis compared obtained via quantitative reverse transcription polymerase chain reaction western blot analysis finally drug efficacy monitored via sersdeep learning analysis using urinary exosomes trastuzumabtreated mice use monitoring system allow proactive responses treatmentresistant issues