Tim Holetzek, Sylvia Euler, Philipp Jaehn, Laura Josephin Schliephacke, Andrea Trunev, Christine Holmberg
[On the Potential of Prevention Counselors in the Primary Care Setting: Evaluation Study of an Intervention in the State of Brandenburg (Germany)]
Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))
although epidemiology immunocompromising condition children evolved time updated epidemiology pediatric pneumocystis infection united states available performed retrospective analysis using kids inpatient database nationally representative sample us pediatric hospital discharges collected 1997 2000 2003 2006 2009 2012 pneumocystis cases identified using international classification diseases ninth revision clinical modification code 1363 among children 018 years age demographic data cases without mortality compared identified 1902 standard error se 95 pneumocystis cases study period pneumocystis hospitalization rate decreased 75 se 091 27 se 031 per million us children 1997 2012 632 decrease cases hiv infection decreased 285 se 56 cases 1997 29 se 7 cases 2012 whereas hematologic malignancy primary immunodeficiency became prominent infants commonly affected 510 cases se 40 allcause inhospital mortality 117 se 13 particularly high among cases hematopoietic stem cell transplant 324se 71 p 0001 pneumocystis infection children showed marked decrease 1997 2012 united states largely driven reduction hivassociated cases cases nonhiv illnesses became prominent hematopoietic stem cell transplantassociated cases particularly high mortality clinicians aware highrisk groups may benefit chemoprophylaxis particularly infancy