Fadi El-Jardali, Lama Bou-Karroum, Mathilda Jabbour, Karen Bou-Karroum, Andrew Aoun, Sabine Salameh, Patricia Mecheal, Chaitali Sinha
Digital health in fragile states in the Middle East and North Africa (MENA) region: A scoping review of the literature
PloS one
aim vitro study investigate effect different toothpaste ingredients biofilm volume vitality established noncontact biofilm removal model multispecies biofilm comprising porphyromonas gingivalis streptococcus sanguinis fusobacterium nucleatum grown proteincoated titanium disks six disks per group exposed 4 seconds noncontact brushing using sonic toothbrush four groups assessed slurries containing different ingredients ie dexpanthenol dp peppermint oil po cocamidopropyl betaine cb sodium hydroxide naoh one positive control group slurry toothpaste pos negative control group physiological saline neg biofilm volume vitality measured using livedead staining confocal laser scanning microscopy statistical analysis comprised descriptive statistics intergroup differences test groups lowest vitality volume found cb 502 119 po 36 105 18 105 m3 respectively significant differences regarding biofilm vitality found comparing cb po p 0033 cb neg p 0014 naoh neg p 0033 pos neg p 0037 however significant intergroup differences biofilm volume observed findings suggest cb toothpaste ingredient considerable impact biofilm vitality even noncontact brushing setting considerable impact biofilm volume found