Audrey Neuprez|Audrey Neuprez|Jean?François Kaux|William Kurth|Christophe Daniel|Thierry Thirion|Jean-Pierre Huskin|Philippe Gillet|Olivier Bruyère|Jean?Yves Reginster
Total joint replacement improves pain, functional quality of life, and health utilities in patients with late-stage knee and hip osteoarthritis for up to 5 years
University of Liège|University of Liège|University of Liège|University of Liège|University of Liège|University of Liège|University of Liège|University of Liège|King Saud University
study identify determinants impact pain function quality life prosthetic replacement surgery 5 years survival patients osteoarthritis oa lower limb total 626 osteoarthritic patients university hospital divided 2 groups according surgical site prospectively followed 5 years hip n 346 knee n 280 replacement validated specific western ontario mcmaster universities arthritis index womac generic sf36 eq instruments assessing quality life used prior surgery yearly thereafter defined good outcome clinically relevant improvement womac greater equal minimally important difference mid regressions showed relationships among preoperative perioperative postoperative measures evolution womac scores 5 years percent change also examined predictors good outcomes beneficial effect quality life observed first year hip knee arthroplasty ha ka maintained 5 years 34 patients study experienced good outcome 8604 ha group 7991 ka group good outcome 5year change womac predicted preoperative ie radiological severity comorbidities disability level education perioperative ie length hospital stay place discharge postoperative ie complications variables two groups joint arthroplasty highly valuable therapeutic strategy hip knee oa patients respond pharmacological management results represent step towards collection robust scientifically sound data facilitate completion health economic analyses field oa