Morgan Congdon, Laura Goldstein, Kristin D Maletsky, Meghan Craven, Stacey Rose, Erin Pete Devon
Pediatric Intersession: An Upfront Flipped-Classroom Curriculum to Promote Pediatric Clerkship Readiness
Journal of medical education and curricular development
hydrogenbonded supramolecular systems usually characterized solution analysis nmr data complexationinduced shifts nuclear overhauser effects noe routine direct detection hydrogen bonding particularly multicomponent mixtures even aid 2d nmr experiments full assignment challenging describe elementary rapid 1h15n hmqc nmr experiment addresses challenges without need complex pulse sequences readily accessible conditions 243263 k 50 mm solutions natural 15n abundance unambiguous assignment 15n resonances facilitates direct detection intra intermolecular hydrogen bonds mechanically interlocked structures quadruply hydrogenbonded dimersof dialkylaminoureidopyrimidinones ureidopyrimidinones diamidonaphthyridinesin single multicomponent mixtures establish tautomeric configuration conformation resolve selfsorted speciation