Xin Zheng|Erica S. Spatz|Xueke Bai|Xiqian Huo|Qinglan Ding|Paul Horak|Xiaofei Wu|Wenchi Guan|Clara K Chow|Xiaoqian Yan|Ying Sun|Xiuling Wang|Haibo Zhang|Shiyuan Liu|Jing Li|Xi Li|John A. Spertus|Frederick A. Masoudi|Harlan M. Krumholz
Effect of Text Messaging on Risk Factor Management in Patients With Coronary Heart Disease
Chinese Academy of Medical Sciences & Peking Union Medical College|National Clinical Research|Yale New Haven Hospital|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|Yale New Haven Hospital|Stanford University|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|The George Institute for Global Health|University of Sydney|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|Chinese Academy of Medical Sciences & Peking Union Medical College|Saint Luke's Hospital|University of Missouri–Kansas City|University of Colorado Anschutz Medical Campus|Yale New Haven Hospital|Yale University
background mobile health technologies low cost scalable interventions potential promote patient engagement behavior change aimed test whether culturally sensitive text messaging intervention supporting secondary prevention improves control risk factors patients coronary heart disease china methods results multicenter singleblinded randomized controlled trial 822 patients mean age 564 sd 95 years 141 women coronary heart disease without diabetes mellitus 37 hospitals china enrolled august 2016 march 2017 addition usual care control group n411 received 2 thank messagesmonth intervention group n411 received 6 text messagesweek 6 months delivered automated computerized system messages provided educational motivational information related diseasespecific knowledge risk factor control physical activity medication adherence primary end point change systolic blood pressure baseline 6 months secondary end points included proportion systolic blood pressure lt140 mm hg smoking status change body mass index ldlc lowdensity lipoprotein cholesterol physical activity assessed using international physical activity questionnaire end points assessed using analyses covariance followup 996 6 months systolic blood pressure significantly lower intervention group compared control group mean change sd 32 143 mm hg 20 150 mm hg p gt005 baseline respectively mean net change 13 mm hg 95 ci 33 08 p 0221 significant differences change ldlc level physical activity body mass index smoking status 2 groups nearly patients intervention group reported text messages useful 961 easy understand 988 appropriate frequency 938 reported willing receive future text messages 948 conclusions text messages supporting secondary prevention among patients coronary heart disease lead greater reduction blood pressure 6 months mobile phone text messaging secondary prevention feasible highly acceptable patients clinical trial registration url httpsclinicaltrialsgov unique identifier nct02888769