Amber Crabtree, Kit Neikirk, Andrea Marshall, Taylor Barongan, Heather K Beasley, Edgar Garza Lopez, Dominique Stephens, Sandra Murray, Elsie C Spencer, Denise Martinez, Chia Vang, Felysha Jenkins, Steven Damo, Zer Vue
Strategies for change: thriving as an individual with a disabilty in STEMM
Pathogens and disease
enzymes play pivotal role various industries enabling efficient ecofriendly sustainable chemical processes however low turnover rates poor substrate selectivity enzymes limit largescale applications rational computational enzyme design facilitated computational algorithms offers targeted less laborintensive approach notable advancement employing rational computational protein engineering strategies overcome issues comprehensively reviewed far article reviews recent developments rational computational enzyme design categorizing three types structurebased sequencebased datadriven machine learning computational design case studies presented demonstrate successful enhancements catalytic activity stability substrate selectivity lastly article provides thorough analysis approaches highlights existing challenges potential solutions offers insights future development directions