Jolijn Vanderauwera|Irène Altarelli|Maaike Vandermosten|Astrid De Vos|Johan Wouters|Pol Ghesquière
Atypical Structural Asymmetry of the Planum Temporale is Related to Family History of Dyslexia
KU Leuven|University of Geneva|KU Leuven|KU Leuven|KU Leuven|KU Leuven
research neural correlates developmental dyslexia indicates atypical anatomical lateralization planum temporale higherorder cortical auditory region yet whether atypical lateralization precedes reading acquisition related familial risk dyslexia currently known study address questions 2 separate cohorts young children adolescents without familial risk dyslexia planum temporale surface area manually labeled bilaterally t1weighted mr brain images 54 prereaders mean age 62 years sd 32 months 33 males 28 adolescents mean age 147 years sd 33 months 11 males half prereaders adolescents familial risk dyslexia prereaders adolescents group comparisons left right planum temporale surface area showed significant interaction hemisphere family history dyslexia participants family risk dyslexia showing greater leftward asymmetry planum temporale effect confirmed analyses restricted normal reading participants altered planum temporale asymmetry thus seems related family history dyslexia