Marie Bakitas|J. Nicholas Dionne?Odom|Salpy V. Pamboukian|José Tallaj|Elizabeth Kvale|Keith M. Swetz|Jennifer Frost|Rachel Wells|Andrés Azuero|Konda Keebler|?matullah Akyar|Deborah Ejem|Karen Steinhauser|Tom E. C. Smith|Raegan W. Durant|Alan Kono
Engaging patients and families to create a feasible clinical trial integrating palliative and heart failure care: results of the ENABLE CHF-PC pilot clinical trial
University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|Dartmouth–Hitchcock Medical Center|University of Alabama at Birmingham|University of Alabama at Birmingham|University of Alabama at Birmingham|Hacettepe University|University of Alabama at Birmingham|Durham VA Medical Center|Duke University|University of Alabama at Birmingham|University of Alabama at Birmingham|Dartmouth–Hitchcock Medical Center
early palliative care epc recommended rarely integrated advanced heart failure hf care engaged patients family caregivers study feasibility site differences twosite epc trial enable chfpc educate nurture advise life ends comprehensive heartcare patients caregivers conducted epc feasibility study 411483115 patients nyha class iiiiv hf caregivers academic medical centers northeast southeast us epc intervention comprised 1 inperson outpatient palliative care consultation 2 telephonic nurse coach sessions monthly calls collected patient caregiverreported outcomes quality life qol symptom health anxiety depression baseline 12 24weeks used linear mixedmodels assess baseline week 24 longitudinal changes enrolled 61 patients 48 caregivers betweensite demographic differences included age race religion marital work status patients 69 caregivers 79 completed intervention sessions however noted large betweensite differences measurement completion 38 southeast vs 72 northeast patients experienced moderate effect size improvements qol symptoms physical mental health caregivers experienced moderate effect size improvements qol depression mental health burden smalltomoderate effect size improvements noted patients hospital icu days emergency visits betweensite demographic attrition participantreported outcomes highlight importance intervention pilottesting culturally diverse populations observations pilot feasibility trial allowed us refine methodology inprogress fullscale randomized clinical efficacy trial clinicaltrialsgov nct03177447 retrospectively registered june 2017