Özge Kısaoğlu, Havva Tel
The impact of hope levels on treatment adherence in psychiatric patients
Acta psychologica
genetic risk modifier testing grmt emerging form genetic testing based common single nucleotide polymorphisms polygenic risk scores potential refine estimates brca12 mutation carriers breast cancer risks however women benefit grmt effective approaches communicating novel risk information needed evaluate patient preferences regarding risk communication materials grmt developed four separate presentations panel genes icon array verbal risk estimate graphical risk estimate hypothetical grmt results using varying risk communication strategies convey different information elements including number risk modifier variants present variant prevalence among brca12 carriers implications uncertainties test results cancer risk thirty brca12 carriers evaluated materials randomized low moderate high breast cancer risk versions qualitative quantitative data obtained inperson interviews across risk versions participants preferred presentation graphical risk estimate often combination verbal risk estimate interest grmt high 767 participants wanted grmt participants valued potential grmt clarify cancer susceptibility provide actionable information many 655 anticipated grmt would make risk management decisions easier women brca12 mutations could highly receptive grmt minimal amount necessary information included result risk communication materials includes graphical verbal estimates future cancer risk findings inform clinical translation grmt manner consistent patients preferences