Jungnam Joo, Eric S Leifer, Michael A Proschan, James F Troendle, Harmony R Reynolds, Erinn A Hade, Patrick R Lawler, Dong-Yun Kim, Nancy L Geller
Comparison of Bayesian and frequentist monitoring boundaries motivated by the Multiplatform Randomized Clinical Trial
Clinical trials (London, England)
extracorporeal membrane oxygenation ecmo remains one intensive therapies newborns united states however limited information resource utilization neonates receiving ecmo conducted retrospective data analysis kids inpatient database 1997 2012 bivariate multivariate analysis completed identify predictors los hospital costs mortality cardiac noncardiac diagnoses neonates receiving ecmo also included bivariate multivariable analysis 5151 ecmo cases survival discharge 62 22 principal cardiac diagnosis adjusting covariates increased mortality associated treatment midwest compared northeast region aor20 p001 decreased among neonates noncardiac diagnosis aor04 p001 living midwest associated longer los 13days increased hospital costs 63000 dollars p001 stratified noncardiac diagnoses infants diagnosis congenital diaphragmatic hernia associated increased mortality 23 p001 longer los 25 p001 increased costs 11100 p001 neonates received ecmo certain regions united states associated poorer survival outcomes well increased los hospital costs retrospective study level iii