S B Yellen|David Cella|Kimberly Webster|Carol Blendowski|Edward H. Kaplan
Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system
Rush University Medical Center|Presbyterian St. Luke's Medical Center
paper reports development validation questionnaire assessing fatigue anemiarelated concerns people cancer using 28item functional assessment cancer therapygeneral factg questionnaire base 20 additional questions related symptoms concerns patients anemia developed thirteen 20 questions dealt fatigue remaining 7 covered concerns related anemia using semistructured interviews 14 anemic oncology patients 5 oncology experts two instruments produced factfatigue factf consisting factg plus 13 fatigue items factanemia factan consisting factf plus 7 nonfatigue items measures turn tested second sample 50 cancer patients hemoglobin levels ranging 7 159 gdl 41item factf 48 item factan scores found stable testretest r 087 internally consistent coefficient alpha range 095096 symptomspecific subscales also showed good stability testretest r range 084090 fatigue subscale showed strong internal consistency coefficient alpha range 093095 internal consistency miscellaneous nonfatigue items lower acceptable alpha range 059070 particularly light strong relationship patientrated performance status hemoglobin level convergent discriminant validity testing revealed significant positive relationship known measures fatigue significant negative relationship vigor predicted lack relationship social desirability total scores scales differentiated patients hemoglobin level p 005 patientrated performance status p 00001 13item fatigue subscale factf 7 nonfatigue items factan also differentiated patients hemoglobin level p 005 patientrated performance status p 0001 factf factan useful measures quality life cancer treatment adding focus problems fatigue anemia fatigue subscale may also stand alone brief reliable valid measure fatigue