Yuhui Li, Xinhui Zhang, Yang Huang, Lei Gao, Zhan Gao, Miao He
The prevalence of Human Immunodeficiency Virus infection among voluntary blood donors in mainland China: A systematic review and meta-analysis
Journal of medical virology
background holmium laser enucleation prostate holep emerged new gold standard treatment benign prostatic hyperplasia however steep learning curve hinders generalization technique therefore need benchtop holep simulator reduce learning curve provide training developed nonbiohazardous holep simulator using modern education theory validated multicenter study materials methods six experts established key components holep simulator delphi consensus three rounds including 250 questions consensus digital design created approved experts used fabricate physical prototype using threedimensional printing hydrogel molding process iterative prototype testing experts completed survey assessing simulator 5point likert scale final approval approved model validated 56 expert novice participants seven institutions using subjective objective performance metrics results consensus reached 85 250 questions experts found physical model adequately replicate 825 required features objective metrics statistically significant p 00001 comparing experts novices enucleation time 374 82 vs 167 68 minutes adenoma weight 796 204 vs 362 99 g complications 6 vs 22 respectively conclusion effectively completed multicenter study develop validate nonbiohazardous benchtop simulator holep modern education theory training curriculum including simulator currently development