Alicia C Brandt, Ahmed Abbas, Cecilia S Dong
Exploring the acceptance of geriatric dentistry programming for undergraduate dental students through stakeholder interviews
Journal of dental education
blastinduced neurotrauma bint important injury paradigm neurotrauma research short communication summarizes current knowledge bint divide bint research several broad categoriesblast wave generation laboratory biomechanics pathology behavioral outcomes repetitive blast animal models clinical neuroimaging investigations humans publications 2000 2023 subdomain considered analysis literature brought salient aspects primary blast waves simulated reasonably laboratory using carefully designed shock tubes various biomechanicsbased theories bint proposed theories may contribute bint generating unique biomechanical signature injury thresholds bint nascent stages thresholds rodents reasonably established thresholds guided primary blast data unavailable humans single blast exposure animal studies suggest dosedependent neuronal pathologies predominantly initiated bloodbrain barrier permeability oxidative stress pathologies typically reversible dosedependent recovery times behavioral changes animals include anxiety auditory recognition memory deficits fear conditioning repetitive blast exposure manifests similar pathologies animals however lower blast overpressures white matter irregularities cortical volume thickness alterations observed neuroimaging investigations military personnel exposed blast behavioral changes human cohorts include sleep disorders poor motor skills cognitive dysfunction depression anxiety overall article provides concise synopsis current understanding consensus controversies potential future directions