Andrea Padoan, Mario Plebani
Dynamic mirroring: unveiling the role of digital twins, artificial intelligence and synthetic data for personalized medicine in laboratory medicine
Clinical chemistry and laboratory medicine
fine particulate air pollution pm25 associated many adverse health outcomes including school absences specifically previous study utah valley area conducted time relatively high air pollution exposure found significant positive correlations school absences air pollution examined hypothesis ambient pm25 exposures associated elementary school absences using quasinatural experiment help control observed unobserved structural factors influence school absences alpine provo salt lake city school districts located valleys subject daily mean pm25 concentrations almost twice high park city school district used seminonparametric generalized additive poisson regression models evaluate associations absences daily pm25 levels 3 districts exposed pollution using park city absences quasicontrol study covered 3 school years 201112201314 school absences strongly associated observed structural factors seasonal trends across school years dayofweek effects holiday effects weather etc however controlling structural factors directly using control district 10 gm increase pm25 associated approximately 17 increase daily elementary school absences exposure ambient air pollution contribute elementary school absences although effect difficult disentangle various factors