Siyuan Chen, Kaichuang Zhang, Jingdong Hu, Na Li, Ao Xu, Haoyang Li, Juexiao Zhou, Chao Huang, Yongguo Yu, Xin Gao
KaryoXpert: An accurate chromosome segmentation and classification framework for karyotyping analysis without training with manually labeled metaphase-image mask annotations
Computers in biology and medicine
minireview reports recent advances biomolecular simulations particularly nucleic acids provides potential effects emerging exascale computing nucleic acid simulations emphasizing need advanced computational strategies fully exploit technological frontier specifically introduce recent breakthroughs computer architectures largescale biomolecular simulations review simulation protocols nucleic acids regarding force fields enhanced sampling methods coarsegrained models interactions ligands also explore integration machine learning methods simulations promises significantly enhance predictive modeling biomolecules analysis complex data generated exascale simulations finally discuss challenges perspectives biomolecular simulations enter dawning exascale computing era