Deliya R. Banda|Alexander Libin|Hong Wang|Sandra M. Swain
A Pilot Study of a Culturally Targeted Video Intervention to Increase Participation of African American Patients in Cancer Clinical Trials
MedStar Health|Washington Hospital|MedStar Health|Georgetown-Howard Universities Center for Clinical and Translational Science|MedStar Health|Washington Hospital
barriers clinical trial participation among african american cancer patients well characterized literature attitudinal barriers encompassing fear distrust concerns ethical misconduct also well documented increase trial accrual attitudes must adequately addressed yet remains lack targeted interventions toward end developed 15minute culturally targeted video designed impact six specific attitudes african american cancer patients toward therapeutic trials conducted pilot study test first intervention increase intention enrollthe primary study outcome selfreported likelihood participate therapeutic trial using mixed methods approach developed attitudes intention enroll therapeutic clinical trials aiet instrument 30item questionnaire measuring six attitudinal barriers african american trial participation enrolled 108 eligible active treatment patients large urban cancer institute mcnemars test matched pairs used assess changes attitudes likelihood enroll clinical trial baseline immediately video pre postvideo aiet summative scores analyzed paired ttest attitudinal barrierpatients likelihood enrolling clinical trial significantly increased postvideo 36 sample showing positive changes intention mcnemars 2 3339 p 001 paired ttests showed significant changes six attitudinal barriers measured via aiet summative scores pre postvideothese data suggest utility video increasing african american participation clinical trials