Eleanor W. Lee|Fiona C. Denison|Kahyee Hor|Rebecca M. Reynolds
Web-based interventions for prevention and treatment of perinatal mood disorders: a systematic review
Queen Elizabeth University Hospital|British Heart Foundation
perinatal depression strikingly common prevalence 1015 adverse effects perinatal depression maternal child health profound considerable costs despite women seek medical attention ehealth providing healthcare via internet accessible effective solution treatment depression general population aimed conduct systematic review webbased interventions prevention treatment mood disorders perinatal period defined start pregnancy 1 year postpartumsix databases searched 26th march 2015 two researchers independently screened articles eligibility 547 screened articles four met inclusion criteria included three randomisedcontrolled trials one feasibility trial total data 1274 participants moose prisma guidelines adhered conduct reporting systematic reviewall studies conducted postpartum period reported improvement maternal mood following intervention significant improvement depressive symptoms measured using validated rating scales edinburgh postnatal depression scale epds either posttreatment followup ranged 3 12 months post study completion two rcts utilising epds epds score reductions mean sem 852 022 range 1946 to1094 919 063 range 2024 1105 treatment groups 516 025 range 1944 1428 681 071 range 2107 1426 comparator groups however attrition within studies ranged 13 61 one study rated good qualitypreliminary data suggests webbased therapies perinatal depression delivered postpartum period may play role improving maternalmood studies needed particularly interventions delivered antenatally research needed address limitations existing evidence base