Xiaotong Li, Raymond E Baser, Karolina Bryl, Lindsay Amann, Susan Chimonas, Jun J Mao
How does pretreatment expectancy influence pain outcomes with electroacupuncture and battlefield acupuncture in cancer survivors?: Pretreatment expectancy and pain reduction by acupuncture
Integrative medicine research
fish photolocomotor behavioral response pbr studies become increasingly prevalent pharmacological toxicological research assess environmental impact various chemicals need standard reliable statistical method analyze pbr data common method currently used univariate analysis variance anova account temporal dependence observations leads incomplete unreliable conclusions repeated measures anova another commonly used method drawbacks interpretability pbr study data observation collected continuously time instead consider observation function apply functional anova fanova pbr data using functional approach accounts temporal dependency also retains full structure data allows straightforward interpretation subregion domain unlike traditional univariate repeated measures anova fanova propose nonparametric requiring minimal assumptions demonstrate disadvantages univariate repeated measures anova using simulated data show overcome applying fanova apply oneway fanova zebrafish data pbr study discuss results reproduced future pbr studies