Geraldine Moreno-Black, Jean Stockard
Two Worlds of Obesity: Ethnic Differences in Child Overweight/Obesity Prevalence and Trajectories
Journal of racial and ethnic health disparities
severe acute respiratory syndrome coronavirus 2 sarscov2 nucleic acid detection gold standard laboratory diagnosis coronavirus disease 2019 covid19 however method high requirements practitioners skills testing sites easy popularize promote application places large hospitals addition detection flux sarscov2 nucleic acid small whole detection process takes much time cannot meet actual needs rapid screening large quantities conditionally approved batch sarscov2 antigen reagents clinical application alleviate contradiction sarscov2 antigen detection offers tradeoff among clinical performance speed accessibility gradual increase clinical application accumulated clinical data show sensitivity specificity sarscov2 antigen assay 80 97 respectively basically meet requirements however sensitivity sarscov2 antigen assay among asymptomatic people low prevalence areas covid19 cannot meet standard leading large number missed diagnoses addition detection ability sarscov2 antigen reagent different sarscov2 mutant strains differs greatly especially escaping covid19 vaccines terms results interpretation highly reliable exclude sarscov2 infection based high negative predictive value sarscov2 antigen assay however low prevalence environment probability false positives sarscov2 antigen assay high positive results need confirmed sarscov2 nucleic acid reagent sarscov2 antigen assay supplement sarscov2 nucleic acid detection never completely replace date sarscov2 nucleic acid detection continues standard laboratory method covid19 diagnosis