Matthew L Romo, Phoebe Jordan, Katharine H McVeigh, Pui Ying Chan, Jeanette A Stingone, Sungwoo Lim, George L Askew
Early intervention and special education in New York City: Patterns of service use and disparities affecting children of colour
Child: care, health and development
prenatal postnatal exposure environmental tobacco smoke ets linked early childhood caries ecc specific molecular mechanisms pathways remain largely unknown caries risk exposure environmental tobacco smoke cares within household air pollution intervention network hapin study aims establish association ets ecc employing epidemiological novel biomarkerbased approaches outline overall design rationale project leverage infrastructure data hapin trial india mount cares study ambidirectional cohort study children n735 aged 35 years undergo ecc examination trained dentist using standard criteria calibrated methods structured questionnaires used gather information sociodemographic variables dietary habits oral hygiene oral healthrelated quality life current exposure ets collect noninvasive minimally invasive biospecimens ie saliva buccal cells dried blood spots urine subset hapin children n120 assess battery biomarkers indicative exposure ets early biological effect epigenetic modifications selfreported objective measures ets exposure collected longitudinally utero early postnatal periods accessed hapin database apply current science data techniques assess association interrelationships ets ecc multiple biomarkers information gathered research published peerreviewed journals summaries shared key stakeholders well patients parentsguardians involved study sri ramachandra institute higher education research ethics board approved study protocol iecni22jul8382 nct02944682