Lori Edwards Suarez, Andreas S Lappas, Nikos G Christodoulou
FACTORS ASSOCIATED WITH NON-ATTENDANCE TO OUTPATIENT CONSULTATION-LIAISON PSYCHIATRY APPOINTMENTS: A RETROSPECTIVE COHORT STUDY
Psychiatria Danubina
carcinogenicity crucial endpoint safety assessment chemicals products last decades development quantitative structureactivity relationship qsar models gained importance regulatory use combination vitro testing expertbased reasoning several classification models predict human rat carcinogenicity models quantitatively assess carcinogenicity humans knowledge slope factor sf parameter describing carcinogenicity potential used especially human risk assessment contaminated sites never modeled inhalation oral exposures study developed classification regression models inhalation oral sfs using data risk assessment information system rais different machine learning approaches models performed well classification accuracies external set 076 074 oral inhalation exposure respectively r2 values 057 065 regression models oral inhalation sfs external validation models might therefore support regulators deprioritizing substances regulatory action weighing evidence context chemical safety assessments moreover models implemented vega platform freely downloadable online