Catherine M. Milte|Natalie Parletta|Jonathan D. Buckley|Alison M. Coates|Ross McD. Young|Peter R. C. Howe
Increased Erythrocyte Eicosapentaenoic Acid and Docosahexaenoic Acid Are Associated With Improved Attention and Behavior in Children With ADHD in a Randomized Controlled Three-Way Crossover Trial
Deakin University|University of South Australia|University of South Australia|University of South Australia|Queensland University of Technology|University of Newcastle Australia
objective investigate effects omega3 polyunsaturated fatty acids n3 pufa docosahexaenoic acid dha eicosapentaenoic acid epa attention literacy behavior children adhd method ninety children randomized consume supplements high epa dha linoleic acid control 4 months crossover design erythrocyte fatty acids attention cognition literacy conners parent rating scales cprs measured 0 4 8 12 months results fiftythree children completed treatment outcome measures showed significant differences three treatments however children blood samples n 7646 increased erythrocyte epa dha associated improved spelling r 365 p lt 001 attention r 540 p lt 001 reduced oppositional behavior r 301 p lt 003 hyperactivity r 310 p lt 001 cognitive problems r 326 p lt 001 diagnostic statistical manual mental disorders 4th ed dsmiv hyperactivity r 270 p 002 dsmiv inattention r 343 p lt 001 conclusion increasing erythrocyte dha epa via dietary supplementation may improve behavior attention literacy children adhd