Julie M Metos, Kelan Sarnoff, Kristine C Jordan
Teachers' Perceived and Desired Roles in Nutrition Education
The Journal of school health
schizophrenia multifaceted psychiatric disorder characterized functional dysconnectivity poses significant challenges clinical practice study explores potential functional connectivity fcbased searchlight multivariate pattern analysis cbsmvpa discriminate schizophrenia patients healthy controls also predicting clinical variables enrolled 112 schizophrenia patients 119 demographically matched healthy controls restingstate functional magnetic resonance imaging data collected wholebrain fc subnetworks constructed additionally clinical assessments cognitive evaluations yielded dataset comprising 36 clinical variables finally cbsmvpa utilized identify subnetworks capable effectively distinguishing patient control groups predicting clinical scores cbsmvpa approach identified 63 brain subnetworks exhibiting significantly high classification accuracies ranging 622 756 distinguishing individuals schizophrenia healthy controls among 5 specific subnetworks centered dorsolateral superior frontal gyrus orbital part inferior frontal gyrus superior occipital gyrus hippocampus parahippocampal gyrus showed predictive capabilities clinical variables within schizophrenia cohort study highlights potential cbsmvpa valuable tool localizing information related schizophrenia terms brain network abnormalities capturing relationship abnormalities clinical variables thus deepens understanding neurological mechanisms schizophrenia