Susan Parker, Ashish A Deshmukh, Baojiang Chen, David R Lairson, Maria Daheri, Sally W Vernon, Jane R Montealegre
Perceived barriers to cervical cancer screening and motivators for at-home human papillomavirus self-sampling during the COVID-19 pandemic: Results from a telephone survey
eLife
severe acute respiratory syndrome coronavirus 2 pandemic hospital resources particularly critical care units overburdened significant impact therapies prognosis patients study aimed identify factors therapies may improve prognosis factors associated increased mortality secondary objective evaluate impact obesity patients observational study conducted 482 patients aged 18 years older diagnosed sarscov2 pneumonia admitted intensive care units 3 national hospitals registered ciberesucicovid database september 2020 march 2021 identifying sample profile risk factors analyzed predictive model constructed crude odd ratios calculated factor additionally logistic regression used build multivariate model adjusting potential confounders final model included variables selected using backward method sample 335 men 695 145 women 3008 aged 6194 1275 years body mass index bmi 2805 257 312 obtained total 113 patients received noninvasive mechanical ventilation common comorbidities high blood pressure 5104 obesity 28 diabetes mellitus 2344 metabolic diseases 2116 chronic heart failure 1805 chronic obstructive pulmonary disease 1162 chronic kidney disease 1016 inhospital 3month 6month postdischarge mortality patients bmi 30 n 135 versus bmi 30 n 347 significantly different p 06 noninvasive mechanical ventilation failed 424 patients bmi 30 compared 55 patients bmi 30 study identified factors associated failure mechanical ventilation common comorbidities congestive heart failure high blood pressure chronic kidney disease severe liver disease diabetes mellitus solid organ transplantation terms ventilatory support patients received highflow nasal oxygen therapy admission lower mortality rates use renal replacement therapy also significantly associated higher mortality