Julia Jaekel|Christian Sorg|J. Baeuml|Peter Bartmann|Dieter Wolke
Head Growth and Intelligence from Birth to Adulthood in Very Preterm and Term Born Individuals
University of Tennessee at Knoxville|University of Warwick|Technical University of Munich|Rechts der Isar Hospital|Technical University of Munich|Rechts der Isar Hospital|University Hospital Bonn|University of Warwick
abstract objectives aim study investigate effects infant toddler head growth intelligence scores early childhood adulthood preterm lt32 weeks gestational age vp andor low birth weight lt1500 g vlbw term born individuals methods 203 vpvlbw 198 term comparisons studied birth adulthood part prospective geographically defined bavarian longitudinal study bls head circumference assessed birth 5 20 months 4 years age intelligence assessed standardized tests childhood 6 8 years kabc 26 years wechsler adult intelligence scale wais structural equation modeling sem used model effect head growth iq results average vpvlbw lower head circumference birth 2761 cm vs 3511 cm mean difference 749 95 confidence interval 709790 lower adult intelligence scores 8898 vs 10254 mean difference 1356 10591653 term born comparison individuals head circumference birth eg total effect 48 p lt001 adult iq head growth childhood predicted intelligence development age 6 26 years vpvlbw term born individuals 70 variance adult iq explained full model effects gestation birth weight intelligence fully mediated head circumference growth conclusions longitudinal investigation birth adulthood indicates head growth proxy brain development intelligence repeated early head circumference assessment adds valuable information screening longterm neurocognitive risk jins 2019 25 48x201356