Suzhen Chen, Yingying Yin, Yuqun Zhang, Wenhao Jiang, Zhenghua Hou, Yonggui Yuan
Childhood abuse influences clinical features of major depressive disorder by modulating the functional network of the right amygdala subregions
Asian journal of psychiatry
health information systems represent opportunity improve care provided people multimorbidity pressing need assess impact clinical outcomes validate intervention study determine whether using digital platform multimorbidity management health information system methis manage multimorbidity improves healthrelated quality life hrqol superiority cluster randomised trial conducted primary healthcare practices 11 allocation ratio public practices lisbon tagus valley lvt region portugal involved previous pilot trial eligible participant level eligible patients people complex multimorbidity aged 50 years older access internet connection communication technology device participants cannot signreadwrite access email account included study intervention combines training programme customised information system methis designed help clinicians adopt goaloriented care model approach encourage patients carers play active role autonomous healthcare primary outcome hrqol measured 12 months physical component scale 12item short form questionnaire sf12 secondary outcomes also measured 12 months include mental health mental component scale sf12 hospital anxiety depression scale also assess serious adverse events trial including hospitalisation emergency services finally 18 months ask general practitioners potentially missed diagnoses research ethics committee lvt region approved trial protocol clinicians patients sign informed consent data management officer handle data publication several scientific papers presentations relevant conferencesworkshops envisaged nct05593835