Janna S E Ottenhoff, Joost T P Kortlever, Emily Z Boersma, David C Laverty, David Ring, Matthew D Driscoll
Adverse Childhood Experiences Are Not Associated With Patient-reported Outcome Measures in Patients With Musculoskeletal Illness
Clinical orthopaedics and related research
speech language skills important social interaction learning study characterised communication abilities verbal individuals sox11 syndrome using standardised parentcarer questionnaire childrens communication checklist ccc2 thirteen parentcarers verbal individuals aged 519 years diagnosed sox11 syndrome completed ccc2 order contextualise findings responses compared norms data noonan syndrome relatively wellknown genetic diagnosis associated communication impairment individuals ccc2 composite score indicated significant communication difficulties language structure speech syntax semantics coherence pragmatic language inappropriate initiation stereotyped language use context nonverbal communication autistic features social relations interests scores lower typically developing norms subscale comparisons revealed relative difference use context compared pragmatic domains stereotyped language inappropriate initiation individual scores showed substantial variation particularly regard language structure profile differences pronounced noonan syndrome specifically domains speech syntax nonverbal communication social relations sox11 syndrome associated communication impairment important assess communication abilities part management individuals sox11 syndrome understand individual strengths difficulties order provide targeted support