Eleonora d’Orsi|André Junqueira Xavier|Snorri Björn Rafnsson|Andrew Steptoe|Eef Hogervorst|Martin Orrell
Is use of the internet in midlife associated with lower dementia incidence? Results from the English Longitudinal Study of Ageing
Universidade Federal de Santa Catarina|Universidade do Sul de Santa Catarina|University College London|University College London|Loughborough University|Institute of Mental Health|University of Nottingham
objectives dementia expected affect one million individuals united kingdom 2025 prodromal phase may start decades clinical onset aim study investigate whether use internet 50 years age associated lower incidence dementia tenyear followupmethods analysed data based 8238 dementia free baseline 20022004 core participants english longitudinal study ageing information baseline use internet obtained questionnaires dementia casesness based participant informant reported physician diagnosed dementia overall score informant questionnaire cognitive decline elderly iqcode cox proportional hazards regression analysis used examining relationship internet use incident dementiaresults 301 501 incident dementia cases followup full multivariable adjustment potential confounding factors baseline internet use associated 40 reduction dementia risk assessed 20062012 hr 060 ci 042085 p 005conclusion study suggests use internet individuals aged 50 years older associated reduced risk dementia additional studies needed better understand potential causal mechanisms underlying association