Joel Michell
Alfred binet and the concept of heterogeneous orders
Frontiers in psychology
italy implemented twodose universal varicella vaccination uvv regionally 2003 2013 nationally 2017 onwards objective analyze regional disparities varicella outcomes resulting disparities vaccine coverage rates vcrs projected 50year timehorizon 20202070 previously published dynamic transmission model updated quantify potential public health impact uvv program italy national regional levels four 2dose vaccine strategies utilizing monovalent v quadrivalent mmrv vaccines evaluated region mmrvmsdmmrvmsd b mmrvgskmmrvgsk c vmsdmmrvmsd vgskmmrvgsk costs reported 2022 euros costs qualityadjusted lifeyears qalys discounted 3 annually strategy three regions lowest firstdose vcr reported increased varicella cases 343 hospitalizations 200 qalys lost 59 payer costs 222 societal costs 146 50year timehorizon compared three regions highest firstdose vcr regions low firstdose vcr sensitive changes vcr high firstdose vcr regions results respect seconddose vcr qualitatively similar although smaller magnitude results similar across vaccine strategies