Joseph B. Koroma|Jen Peterson|Aiah A Gbakima|Francis E. Nylander|Foday Sahr|Ricardo J. Soares Magalhães|Yaobi Zhang|Mary H. Hodges
Geographical Distribution of Intestinal Schistosomiasis and Soil-Transmitted Helminthiasis and Preventive Chemotherapy Strategies in Sierra Leone
Ministry of Health and Sanitation|Helen Keller International|University of Sierra Leone|University of Sierra Leone|University of Queensland|Helen Keller International|Helen Keller International
national baseline mapping schistosomiasis soiltransmitted helminthiasis sth performed sierra leone aim provide necessary tools ministry health sanitation plan intervention strategies national integrated control program neglected tropical diseases according world health organization guidelines preventative chemotherapy pct future monitoring evaluation53 primary schools randomly selected twostaged random sampling throughout country approximately one hundred children aged 516 years age systematically selected school stool samples examined field laboratory total 5651 samples examined data analyzed multivariable logistic regression models using modelbased geostatistics spatial analysis predicted mansoni infection positively associated population density elevation large cluster high risk mansoni infection prevalence 70 north eastern areas country line observed prevalence kono 638783 koinadugu 216821 kailahun 435526 kenema 61689 tonkolili 0573 hookworm infection negatively associated population density land surface temperature high across sierra leone large cluster high infection risk prevalence 70 northeastern part country remarkably low prevalence ascaris lumbricoides 72 trichuris trichiura 33 recorded compared results published 1990sresults justify pct schistosomiasis school age children atrisk adults every year highrisk communities five districts every two years moderaterisk communities one district high prevalence sth particularly hookworm coupled widespread anemia according national report sierra leone suggests one district justifying biannual pct sth preschool children school age children atrisk adults pct sth remaining district kono justified annually