Annette W Burgess, Georgina M Luscombe, George Ramsey-Stewart
An intensive anatomy by whole-body dissection elective: A longitudinal study
Clinical anatomy (New York, N.Y.)
many survivors critical illnesses intensive care unit icu suffer physical disability months treatment icu identifying patients susceptible disability essential purpose study modify model early inicu prediction patients risk physical disability two months treatment icu prospective multicenter derivationvalidation study conducted 1 july 2015 31 august 2016 modified model consisting three risk factors derivation group tested modified model validation group asked physical abilities admitted two months discharge icu binary adl staircases questionnaire univariate multivariate logistic regression used modify physical disability components derivation data set receiver operating characteristic curves used determine sensitivity specificity threshold values validation group fivehundred nineteen survivors enrolled derivation group 271 validation multivariable analysis odds ratio physical disability significantly increased educational level elementary school 3696 95ci 18147529 inability sit without support 1516 95ci 7982880 fracture 1274 95ci 4473630 multivariable validation model indicated education level inability sit without support fracture simultaneously sensitivity 713 specificity 882 lr 60 lr 033 ppv 909 npv 649 predict physical disability applying coefficients derived multivariable logistic regression fitted derivation dataset validation dataset computing diagnostic index sensitivity 100 specificity 605 lr 25 lr 0003 ppv 808 npv 100 modified model excellent prediction ability physical disability auc se 0881 0016 low education level inability sit without support fracture modified model associated development physical disability discharge icu therefore clinical variables considered organizing followup care icu survivors