Abhijit Gadkari|Colleen A. McHorney
Unintentional non-adherence to chronic prescription medications: How unintentional is it really?
MSD (United States)|MSD (United States)
unintentional nonadherence characterized passively inconsistent medicationtaking behavior forgetfulness carelessness objectives 1 study prevalence predictors unintentional nonadherence 2 explore interrelationship intentional unintentional nonadherence relation patients medication beliefs conducted crosssectional survey adults asthma hypertension diabetes hyperlipidemia osteoporosis depression harris interactive chronic illness panel analytic sample study included 24017 adults selfidentified persistent prescription medications index disease answered three questions unintentional nonadherence forgot ran careless 11 questions intentional nonadherence three multiitem scales assessing perceived need medication k 10 perceived medication concerns k 6 perceived medication affordability k 4 logistic regression used model predictors unintentional nonadherence behavior baron kennys regression approach used test mediational effect unintentional nonadherence relationship medication beliefs intentional nonadherence bootstrapping employed confirm statistical significance results index disease 62 forgot take medication 37 run medication 23 careless taking medication common multivariate predictors p 001 three behaviors 1 lower perceived need medications 2 medication affordability problems 3 worse selfrated health 4 diabetes osteoporosis relative hypertension 5 younger age unique statisticallysignificant predictors three behaviors forgot take medications greater concerns index medication male gender b run medications nonwhite race asthma higher number total prescription medications c careless greater medication concerns mediational tests confirmed hypothesis effect medication beliefs perceived need concerns affordability intentional nonadherence mediated unintentional nonadherence study sample unintentional nonadherence appear random predicted medication beliefs chronic disease sociodemographics data suggests importance unintentional nonadherence may lie potential prognostic significance future intentional nonadherence health care providers may consider routinely inquiring unintentional nonadherence order proactively address patients suboptimal medication beliefs choose discontinue therapy together