Ryoichi Nakajima, Hiroshi Kamada, Taishu Kasai, Yohei Tomaru, Miki Waku, Ayano Yamaki, Atsuhiko Ban, Shumpei Miyakawa, Masashi Yamazaki, Hitoshi Shiraki
Effect of temporary school closure due to COVID-19 on musculoskeletal function in elementary school children
Journal of rural medicine : JRM
primary aldosteronism natural model chronic aldosterone excess humans associated symptoms anxiety depression cognitive deficits inherent symptomatology depression anxiety disorders mineralocorticoid receptors aldosterone appear play role memory aldosterone additionally supposed risk factor cognitive decline patients essential hypertension objective study investigate possible effects chronically high aldosterone concentrations cognitive function range cognitive dimensions assessed 19 patients 9 males 10 females mean age 471 125 standardized treatment several rating scales anxiety depression quality life sleep administered cognitive parameters compared standard norms large healthy standardization sample patients showed increased levels anxiety depression without meeting diagnostic criteria disorder besides numerically lower attention score patients show significant differences cognitive dimensions anxiety depression negatively correlated quantitative performance males females negative correlation sleep disturbances abstract reasoning positive correlation quantitative performance found data showed specific effect chronic aldosterone tested cognitive parameters overall least younger patients indicate sexually dimorphic regulation processes