Charles G Jose, Rachel Lucy, Alma Manabat Parker, Joana Clere, Linda Montecillo, Allison M Cole
Pakikisama: Filipino Patient Perspectives on Health Care Access and Utilization
Journal of the American Board of Family Medicine : JABFM
background objectives risks uveitis development among pediatric patients syndrome ds remain unclear therefore aimed determine risk uveitis following diagnosis ds materials methods multiinstitutional retrospective cohort study utilized trinetx database identify individuals aged 18 years younger without diagnosis ds 1 january 2000 31 december 2023 nonds cohort consisted randomly selected control patients matched selected variables included gender age ethnicity certain comorbidities main outcome incidence newonset uveitis statistical analysis uveitis risk reported using hazard ratios hrs 95 confidence intervals cis separate analyses uveitis risk among ds patients based age groups gender also performed results total 53993 individuals ds 4683 female 5826 white mean age index 521 576 years 53993 nonds individuals 4556 female 5828 white mean age index 521 576 years recruited trinetx database analysis also showed overall increased risk uveitis among ds patients hr 133 ci 089199 compared nonds cohort across 23year study period subgroup analyses based different age groups showed aged 01 year hr 136 ci 068272 05 years hr 134 ci 075239 618 years hr 115 ci 067196 found association uveitis risk compared respective nonds comparators also increased risk uveitis among females hr 149 ci 087256 males hr 082 ci 048141 ds compared respective nonds comparators conclusions study found overall increased risk uveitis following diagnosis ds compared matched control population