May A. Beydoun|Marie Fanelli Kuczmarski|Melissa Kitner?Triolo|Hind A. Beydoun|Jay S. Kaufman|Marc Mason|Michele K. Evans|Alan B. Zonderman
Dietary Antioxidant Intake and Its Association With Cognitive Function in an Ethnically Diverse Sample of US Adults
National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health|National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health|National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health|National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health|National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health|National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health|National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health|National Institute on Aging|University of Delaware|Eastern Virginia Medical School|McGill University|MedStar Health
background dietary antioxidants inhibit reactions accompanying neurodegeneration thus prevent cognitive impairment describe associations dietary antioxidants cognitive function large biracial population testing moderation sex race age mediation depressive symptoms methods crosssectional analysis 1274 adults 541 men 733 women aged 30 64 years baseline mean standard deviation 475 93 healthy aging neighborhoods diversity across lifespan study baltimore city md cognitive performance domains memory languageverbal attention spatial psychomotor speed executive function global mental status assessed 20item center epidemiologic studies depression scale used measure depressive symptoms dietary intake assessed two 24hour recalls estimating daily consumption total carotenoids vitamins c e per 1000 kcal results among key findings 1 standard deviation 202 mg1000 kcal higher vitamin e associated higher score verbal memory immediate recall 064 019 p 001 better languageverbal fluency performance 053 016 p 001 particularly among younger age group women higher vitamin e intake 068 021 p 001 better performance psychomotor speed test vitamin everbal memory association partially mediated depressive symptoms proportion mediated 1316 conclusions sum future cohort studies dietary interventions focus associations dietary vitamin e cognitive decline specifically domains verbal memory verbal fluency psychomotor speed