Susanne G Johnson, Birgitte Espehaug, Lillebeth Larun, Donna Ciliska, Nina Rydland Olsen
Occupational Therapy Students' Evidence-Based Practice Skills as Reported in a Mobile App: Cross-Sectional Study
JMIR medical education
biomarkers exposures infection environmental chemicals measured small volumes blood extracted newborn dried blood spots dbs underscoring potential utility populationbased research however studies evaluated feasibility utility resource particularly factors associated parental consent ability retrieve banked samples sufficient remaining volume epidemiologic research 8 months postpartum 5034 mothers infants born 20082010 new york 57 counties excluding new york city asked consent use residual dbs quantification cytokines environmental chemicals mothers part upstate kids study longitudinal birth cohort designed evaluate child development 3 years age information parental infant characteristics obtained birth certificates maternal report 4 months postpartum multivariate logistic regression used identify factors associated parental consent successful retrieval dbs sixtytwo percent n 3125 parents consented factors significantly associated consent included nonhispanic ethnicity odds ratio 204 95 ci 143294 parity 129 105157 maternal obesity 142 111180 reported alcohol use pregnancy 151 112206 however associations corresponded small absolute differences proportions 4 8 suggesting two groups remained comparable infant characteristics preterm delivery significantly differ consent status among singletons ventilator use 239 95 ci 106541 remained borderline significant among twins adjusted analyses among consented infants 99 least one 32 mm punch successfully retrieved biomarker analyses 84 full dbs circle available parental characteristics varied slightly consent availability samples research purposes high demonstrating feasibility resource population based research