A. Millier|Ulrike Schmidt|M. C. Angermeyer|D. Chauhan|V. Murthy|Mondher Toumi|N. Cadi-Soussi
Humanistic burden in schizophrenia: A literature review
Creativ-Ceutical (France)|University of Cagliari|Takeda (United Kingdom)|Takeda (United Kingdom)|Claude Bernard University Lyon 1|Takeda (Switzerland)
schizophrenia complex disease affects 1 population disease considerable impact patients health wellbeing also surrounding environment costs diseases management remain large individuals society literature economic impact schizophrenia abundant studies focused humanistic burden concern patients also caregivers relatives neighbours others patients daily life burden appears several dimensions including treatment side effects impact caregivers features patients environment aim review consider compile describe humanistic burden schizophrenia documented literature conducted literature review assessing worldwide disease burden schizophrenia taking account humanistic burden topics search considered several databases including embase medline cochrane library german institute medical documentation information dimdi ispor conference websites search identified 200 literature reviews covering several dimensions humanistic burden documenting many issues main findings included high death rates may explained longlasting negative health habits disease treatmentrelated metabolic disorders consequent increased frequencies cardiovascular diseases coexisting depression found adverse consequence course schizophrenia progression morbidity mortality cognitive impairment also adds burden schizophrenia social impairment worsened underestimated stigmatisation lack corresponding awareness within professional social spheres finally caregiver burden found considerable humanistic burden among patients schizophrenia substantial potentially impacted comorbid depressive symptoms caregiver burden cognitive impairment effects treatment humanistic burden addition economic burden need explored future trials