Gina Conti?Ramsden|Milena Falcaro|Zoë Simkin|Andrew Pickles
Familial loading in specific language impairment: patterns of differences across proband characteristics, gender and relative type
University of Manchester|University of Manchester|University of Manchester|University of Manchester
little doubt environmental factors genes likely make important contributions aetiology specific language impairment sli commonly proposed model understanding influences multifactorial model present study examine two expectations based model systematic relationship severity proband language scores rate severity sli relatives relatives strongly affected relatives proband rarely affected gender female latter require higher genetic liability become equally impaired ninetythree probands 300 firstdegree relatives participated study results showed relationship proband severity age 14 increased rate sli relatives relationship strong child siblings significant respect rate sli severity range language literacy measures contrast higher levels sli among relatives female rather male probands entirely disproved