Markus Hofmann|Martin J. Herrmann|Ippeita Dan|Hellmuth Obrig|Markus Conrad|Lars Kuchinke|Arthur Jacobs|Andreas J. Fallgatter
Differential activation of frontal and parietal regions during visual word recognition: An optical topography study
Freie Universität Berlin|Universitätsklinikum Würzburg|Food Research Institute|Charité - Universitätsmedizin Berlin|Freie Universität Berlin|Freie Universität Berlin|Freie Universität Berlin|Universitätsklinikum Würzburg
present study examined cortical oxygenation changes lexical decision words pseudowords using functional nearinfrared spectroscopy fnirs focal hyperoxygenation indicator functional activation compared three target areas left hemisphere 52channel hitachi etg4000 used covering superior frontal gyrus sfg left inferior parietal gyrus ipg left inferior frontal gyrus ifg allow anatomical inference recently developed probabilistic mapping method used determine likely anatomic locations changes cortical activation tsuzuki jurcak v singh ak okamoto watanabe e dan 2007 virtual spatial registration standalone fnirs data mni space neuroimage 43 4 15061518 subjects made lexical decisions 50 low 50 high frequency words 100 pseudowords respect lexicality effect words elicited larger focal hyperoxygenation comparison pseudowords two regions identified sfg left ipg sfg activation difference interpreted reflect decisionrelated mechanisms according multiple readout model grainger j jacobs 1996 orthographic processing visual word recognition multiple readout model psychological review 103 518565 greater oxygenation response words left ipg suggests region connects orthographic phonological semantic representations decrease deoxygenated hemoglobin observed low frequency comparison high frequency words region identified ifg regions sensitivity word frequency suggests involvement graphemephoneme conversion role selection preactivated semantic candidates