Lei Bai, Dongang Wang, Hengrui Wang, Michael Barnett, Mariano Cabezas, Weidong Cai, Fernando Calamante, Kain Kyle, Dongnan Liu, Linda Ly, Aria Nguyen, Chun-Chien Shieh, Ryan Sullivan, Geng Zhan, Wanli Ouyang, Chenyu Wang
Improving multiple sclerosis lesion segmentation across clinical sites: A federated learning approach with noise-resilient training
Artificial intelligence in medicine
centuries philosophical clinical studies emphasized fundamental dichotomy emotion cognition instance behavioralemotional memory explicitrepresentative memory however last decades cognitive neuroscience highlighted data indicating emotion cognition well underlying neural networks fact close interaction first turns emotion serve cognition exemplified critical contribution decisionmaking enhancement episodic memory second also observed reciprocally cognitive processes reasoning conscious appraisal explicit representation events modulate emotional responses like promoting reducing fear third neurobiological data indicate reciprocal amygdalarhippocampal influences underlie mutual regulation emotion cognition supporting view present review discusses experimental data obtained rodents indicating hippocampal amygdalar systems regulate functional outcomes also qualify specific emotional memory representations specific activations interactions specifically review consistent behavioral electrophysiological pharmacological biochemical imaging data unveiling direct contribution amygdala hippocampalseptal system identification predictor threat different situations fear conditioning suggestion two brain systems interplay determine selection relevant emotional stimuli thereby contributing adaptive value emotional memory hence beyond mutual quantitative regulation two brain systems described far develop idea different activations hippocampus amygdala leading specific configurations neural activity qualitatively impact formation emotional memory representations thereby producing either adaptive maladaptive fear memories