Diana Sarokhani, Mandana Sarokhani, Ali Hasanpour Dehkordi, Reza Ghanei Gheshlagh, Moloud Fakhri
Prevalence of obesity and overweight in Iranian students: a systematic review and meta-analysis
Journal of pediatric endocrinology & metabolism : JPEM
evaluate 1 distribution gray matter gm atrophy myelin oligodendrocyte glycoprotein antibodyassociated disease mogad aquaporin4 antibodypositive neuromyelitis optica spectrum disorder aqp4nmosd relapsingremitting multiple sclerosis rrms 2 relationship gm volumes white matter lesions various brain regions within disease retrospective multicenter analysis magnetic resonance imaging data included patients mogadaqp4nmosdrrms nonacute disease stage voxelwise analyses general linear models used evaluate relevance regional gm atrophy significant results p 005 volumes atrophic areas reported studied 135 mogad patients 135 aqp4nmosd 175 rrms 144 healthy controls hc compared hc mogad showed lower gm volumes temporal lobes deep gm insula cingulate cortex 7579 cm3 aqp4nmosd occipital cortex 3283 cm3 rrms diffusely gm 26061 cm3 mogad showed pronounced temporal cortex atrophy rrms 671 cm3 whereas aqp4nmosd displayed greater occipital cortex atrophy rrms 1982 cm3 rrms demonstrated pronounced deep gm atrophy comparison mogad 2790 cm3 aqp4nmosd 4704 cm3 mogad higher periventricular corticaljuxtacortical lesions linked reduced temporal cortex deep gm insula volumes rrms diffuse gm atrophy associated lesions locations aqp4nmosd showed lesiongm volume correlation gm atrophy widespread rrms compared two conditions mogad primarily affects temporal cortex whereas aqp4nmosd mainly involves occipital cortex mogad rrms lesionrelated tract degeneration associated atrophy link absent aqp4nmosd ann neurol 2024