Matthew J. Crowley|Leah L. Zullig|Bimal R. Shah|Ryan Shaw|Jennifer H. Lindquist|Eric D. Peterson|Hayden B. Bosworth
Medication Non-Adherence After Myocardial Infarction: An Exploration of Modifying Factors
Durham VA Medical Center|Durham VA Medical Center|Duke University|Durham VA Medical Center|Durham VA Medical Center|Duke University|Duke University
medication nonadherence major impediment management cardiovascular disease risk factors better understanding modifying factors underlying medication nonadherence among individuals known cardiovascular disease may inform approaches addressing nonadherencethe purpose study identify demographic patient characteristics medical comorbidities psychosocial factors health beliefrelated factors associated medication nonadherence among patients known cardiovascular diseasewe performed secondary analysis baseline data randomized trialthe study included 405 patients diagnosis hypertension history acute myocardial infarction diagnosed within threeyear period prior enrollmentbaseline demographics patient characteristics medical comorbidities psychosocial factors health beliefrelated factors patientreported medication nonadherence analyzedof 405 patients 173 427 reported medication nonadherence factors associated nonadherence bivariate analysis included younger age nonwhite race less 12 years education smoking financial insecurity identifying nervous tense higher life chaos score greater worry myocardial infarction greater worry stroke using multivariable modeling determined age 097 per additional year 95 ci 095099 life chaos 106 per additional point 95 ci 100111 worry stroke 112 per additional point 95 ci 101125 remained significantly associated selfreported medication nonadherencewe found worry stroke higher life chaos younger age significantly associated selfreported medication nonadherence patients cardiovascular disease history myocardial infarction research exploring factors targets intervention needed additional research examining modifiable causes medication nonadherence among patients cardiovascular disease