Fragile x Syndrome is a genetic disease which is caused by mutation in the Fragile x Mental Retardation 1(FMR1) gene in X chromosome. Generally, these mutation (>200 repeats of CGG) occurs at in the 5' untranslated region of FMR1. In around 2% of cases, Fragile X syndrome can occur as a result of point mutation in FMR1 gene.
Normally, the FMR1 gene makes a protein you need for your brain to grow properly. A defect in this gene makes your body produce too little of the protein, or none at all.
Boys and girls can both be affected, but because boys have only one X chromosome, a single fragile X is likely to affect them more severely. You can have Fragile X syndrome even if your parents do not have it.
What are the causes of Fragile X syndrome?
Fragile x Syndrome is a genetic disease which is caused by mutation in {{ORGANIZATION}} 1(FMR1) gene in X chromosome. Generally, these mutation (>200 repeats of {{ORGANIZATION}}) occurs at in the 5' untranslated region of {{ORGANIZATION}}. In around 2% of cases, Fragile X syndrome can occur as a result of point mutation in FMR1 gene.
Normally, the FMR1 gene makes a protein you need for your brain to grow properly. A defect in this gene makes your body produce too little of the protein, or {{EMAIL}}.
Boys and girls can both be affected, but because boys have only one X chromosome, a single fragile X is likely to affect them more severely. You can have Fragile X syndrome even if your parents do not have it.