The outcome varies, depending on:
The class of lupus nephritis: Focal lupus nephritis, minimal mesangial lupus nephritis and mesangial proliferative lupus nephritis have better prognosis than other classes. And, advanced sclerosis lupus nephritis carries a poor prognosis. Nephrotic syndrome carries worse prognosis. Creatinine level: Patients with elevated creatinine (>3 mg/dL) at presentation have worse outcomes. Patients with persistently elevated anti-dsDNA and low C3 and C4 levels have poorer outcomes. Renal biopsy findings showing diffuse lupus nephritis or high chronicity index suggest worse prognosis. Age onset of lupus nephritis: Young age onset carries worse prognosis. Male gender have poorer outcomes than female. Black race have worse outcomes than other races.
What to expect if I have Lupus nephritis  (Outlook/Prognosis)?
The outcome varies, depending on:
The class of lupus nephritis: Focal lupus nephritis, minimal mesangial lupus nephritis and mesangial proliferative lupus nephritis have better prognosis than other classes. And, advanced sclerosis lupus nephritis carries a poor prognosis. Nephrotic syndrome carries worse prognosis. Creatinine level: Patients with elevated creatinine (>3 mg/dL) at presentation have worse outcomes. Patients with persistently elevated anti-dsDNA and low C3 and C4 levels have poorer outcomes. Renal biopsy findings showing diffuse lupus nephritis or high chronicity index suggest worse prognosis. Age onset of lupus nephritis: Young age onset carries worse prognosis. Male gender have poorer outcomes than female. Black race have worse outcomes than other races.