It is not known how many people are affected by PJS. The National Institutes of Health estimates that it affects about 1 in 25,000 to 300,000 births.
There are 2 types of PJS:
Familial PJS may be due to a mutation in a gene called STK11. The genetic defect can be inherited through families as an autosomal dominant trait. That means if 1 of your parents has this type of PJS, you have a 50% chance of inheriting the gene and having the disease. Sporadic PJS is not passed down through families and appears unrelated to an STK11 gene mutation.
What causes Peutz-Jeghers syndrome?
It is not known how many people are affected by {{ORGANIZATION}}. {{ORGANIZATION}} estimates that it affects about 1 in 25,000 to 300,000 births.
There are 2 types of {{ORGANIZATION}}:
Familial {{ORGANIZATION}} may be due to a mutation in a gene called STK11. The genetic defect can be inherited through families as an autosomal dominant trait. That means if 1 of your parents has this type of {{ORGANIZATION}}, you have a 50% chance of inheriting the gene and having the disease. Sporadic {{ORGANIZATION}} is not passed down through families and appears unrelated to an STK11 gene mutation.