Bone marrow is the soft, fatty tissue inside your bones. Stem cells are immature cells in the bone marrow that give rise to all of your blood cells. Your blood is made up of:
Red blood cells (which carry oxygen to your tissues) White blood cells (which fight infection) Platelets (which help your blood clot)
Scarring of the bone marrow means the marrow is not able to make enough blood cells. Anemia, bleeding problems, and a higher risk of infections may develop as a result.
The liver and spleen may try to compensate and make some of these blood cells, a process called'extramedullary hematopoiesis'. This causes these organs to swell.
The disorder usually develops slowly in people over age 50.
Diseases such as leukemia and lymphoma may also cause bone marrow scarring. This is called secondary myelofibrosis.
What causes Myelofibrosis?
Bone marrow is the soft, fatty tissue inside your bones. Stem cells are immature cells in the bone marrow that give rise to all of your blood cells. Your blood is made up of:
Red blood cells (which carry oxygen to your tissues) White blood cells (which fight infection) Platelets (which help your blood clot)
Scarring of the bone marrow means the marrow is not able to make enough blood cells. Anemia, bleeding problems, and a higher risk of infections may develop as a result.
The liver and spleen may try to compensate and make some of these blood cells, a process called'extramedullary hematopoiesis'. This causes these organs to swell.
The disorder usually develops slowly in people over age 50.
Diseases such as leukemia and lymphoma may also cause bone marrow scarring. This is called secondary myelofibrosis.