The outcome depends on the condition that is causing the problem. In general, acute hyponatremia, which occurs in less than 48 hours, is more dangerous than hyponatremia that develops slowly over time. When sodium levels fall slowly over a period of days or weeks (chronic hyponatremia), the brain cells have time to adjust and swelling is minimal. In COVID 19 patients, hyponatremia was associated with increased risk of encephalopathy and mechanical ventilation.
What to expect if I have Hyponatremia  (Outlook/Prognosis)?
The outcome depends on the condition that is causing the problem. In general, acute hyponatremia, which occurs in less than 48 hours, is more dangerous than hyponatremia that develops slowly over time. When sodium levels fall slowly over a period of days or weeks (chronic hyponatremia), the brain cells have time to adjust and swelling is minimal. In COVID 19 patients, hyponatremia was associated with increased risk of encephalopathy and mechanical ventilation.