There are some factors may increase the risk of acquiring the colorectal cancer potentially. These risk factors are outlined in the table below:
Colorectal polyps: Person with a history of adenomatous polyps (adenomas) is at increased risk of developing colorectal cancer, especially with large or many of them.
Inflammatory bowel diseases such as ulcerative colitis and Crohn's disease: Clinical surveys has show the close relationship between inflammatory bowel disease and colorectal cancer.
Family history of colorectal cancer: The reasons are not clear in all cases. Inherited genes, shared environmental factors and some combination of these may contribute to the development of colorectal cancer.
Familial adenomatous polyposis (FAP): FAP is caused by changes (mutations) in the APC gene that a person inherits from his or her parents. About 1% of all colorectal cancers are due to FAP.
Hereditary non-polyposis colon cancer (HNPCC): Clinical survey suggest that the lifetime risk of colorectal cancer in people with this condition may be as high as 70% to 80%.
Turcot syndrome: This is a rare inherited condition in which people are at increased risk of adenomatous polyps and colorectal cancer.
Peutz-Jeghers syndrome: People with this syndrome are at greatly increased risk for multiple kind of cancer besides colorectal cancer.
Type 2 diabetes: Clinical data show that people with type 2 diabetes have an increased risk of developing colorectal cancer.
Lifestyle-related factors such as diets high in red meats and poor in vegetables and fruits, physical inactivity, smoking and alcohol abuse, obesity and so on.
Racial and ethnic background: Among all racial groups in the United States, African Americans have the highest incidence and mortality rates to develope colorectal cancer. The reason is not yet clear.
Age: Both youth and aged can develop colorectal cancer. But the chances increase markedly after age 50.
Who is at highest risk for Hereditary nonpolyposis colorectal cancer ?
There are some factors may increase the risk of acquiring the colorectal cancer potentially. These risk factors are outlined in the table below:
Colorectal polyps: Person with a history of adenomatous polyps (adenomas) is at increased risk of developing colorectal cancer, especially with large or many of them.
Inflammatory bowel diseases such as ulcerative colitis and {{NAME}}'s disease: Clinical surveys has show the close relationship between inflammatory bowel disease and colorectal cancer.
Family history of colorectal cancer: The reasons are not clear in all cases. Inherited genes, shared environmental factors and some combination of these may contribute to the development of colorectal cancer.
Familial adenomatous polyposis ({{ORGANIZATION}}): {{ORGANIZATION}} is caused by changes (mutations) in the {{ORGANIZATION}} gene that a person inherits from his or her parents. About 1% of all colorectal cancers are due to {{ORGANIZATION}}.
Hereditary non-polyposis colon cancer ({{ORGANIZATION}}): Clinical survey suggest that the lifetime risk of colorectal cancer in people with this condition may be as high as 70% to 80%.
Turcot syndrome: This is a rare inherited condition in which people are at increased risk of adenomatous polyps and colorectal cancer.
Peutz-Jeghers syndrome: People with this syndrome are at greatly increased risk for multiple kind of cancer besides colorectal cancer.
Type 2 diabetes: Clinical data show that people with type 2 diabetes have an increased risk of developing colorectal cancer.
Lifestyle-related factors such as diets high in red meats and poor in vegetables and fruits, physical inactivity, smoking and alcohol abuse, obesity and so on.
Racial and ethnic background: Among all racial groups in the United States, African Americans have the highest incidence and mortality rates to develope colorectal cancer. The reason is not yet clear.
Age: Both youth and aged can develop colorectal cancer. But the chances increase markedly after age 50.