Neurofibromatosis causes unchecked growth of tissue along the nerves. This can put pressure on affected nerves and cause pain, severe nerve damage, and loss of function in the area served by the nerve. Problems with sensation or movement can occur, depending on the nerves affected.
The condition can be very different from person to person, even among people in the same family who have the NF1 gene.
The coffee -with- milk (café-au-lait) spots are the hallmark symptom of neurofibromatosis. Although many healthy people have 1 or 2 small café-au-lait spots, adults with 6 or more spots greater than 1.5 cm in diameter are likely to have neurofibromatosis. In most people with the condition, these spots may be the only symptom.
Other symptoms may include:
Blindness Convulsions Freckles in the underarm or groin Large, soft tumors called plexiform neurofibromas, which may have a dark color and may spread under the surface of the skin Pain (from affected peripheral nerves) Small, rubbery tumors of the skin called nodular neurofibromas
What are the symptoms of Peripheral neurofibromatosis or Neurofibromatosis type 1?
Neurofibromatosis causes unchecked growth of tissue along the nerves. This can put pressure on affected nerves and cause pain, severe nerve damage, and loss of function in the area served by the nerve. Problems with sensation or movement can occur, depending on the nerves affected.
The condition can be very different from person to person, even among people in the same family who have the NF1 gene.
The coffee -with- milk (café-au-lait) spots are the hallmark symptom of neurofibromatosis. Although many healthy people have 1 or 2 small café-au-lait spots, adults with 6 or more spots greater than 1.5 cm in diameter are likely to have neurofibromatosis. In most people with the condition, these spots may be the only symptom.
Other symptoms may include:
Blindness Convulsions Freckles in the underarm or groin Large, soft tumors called plexiform neurofibromas, which may have a dark color and may spread under the surface of the skin Pain (from affected peripheral nerves) Small, rubbery tumors of the skin called nodular neurofibromas