Researchs demonatrate that mutations in the SRD5A2 gene cause 5-alpha reductase deficiency. As a result of SRD5A2 mutations, the body cannot effectively convert testosterone to dihydrotestosterone (DHT), which plays an important role in the formation of external genitalia before birth.
Who is at risk for 5-alpha-reductase deficiency?
{{NAME}} demonatrate that mutations in the SRD5A2 gene cause 5-alpha reductase deficiency. As a result of SRD5A2 mutations, the body cannot effectively convert testosterone to dihydrotestosterone ({{ORGANIZATION}}), which plays an important role in the formation of external genitalia before birth.