Causes of Nephrotic Syndrome can be primary (that is; from the kidney glomeruli) or secondary (from an external insult to the kidney). Primary cause of Nephrotic Syndrome is often referred to as Idiopathic i.e. there are no known causes for the kidney abnormality. Such is the case in Minimal change kidney disease seen in children. Primary causes of nephrotic syndrome are usually described by the histology, e.g. minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS) and membranous nephropathy (MN). These diseases are considered to be " diagnoses of exclusion," meaning they are diagnosed only after secondary causes have been excluded.
Secondary Nephrotic Syndrome is nephrotic syndrome that is associated with well-known kidney diseases like autoimmune disease like Henoin Scholein purpura, IgA nephropathy, lupus nephritis etc. Secondary Nephrotic syndrome is also associated with post streptococcal glomerulonephritis, Alport's syndrome. It has also been associated with allergic reactions, drugs like NSAIDs, vaccination like the influenza and pneumococcal vaccines, tumors and viral infections.
A complete list of possible causes of nephrotic syndrome can be found here.
What causes Nephrotic syndrome?
Causes of Nephrotic Syndrome can be primary (that is; from the kidney glomeruli) or secondary (from an external insult to the kidney). Primary cause of Nephrotic Syndrome is often referred to as Idiopathic i.e. there are no known causes for the kidney abnormality. Such is the case in Minimal change kidney disease seen in children. Primary causes of nephrotic syndrome are usually described by the histology, e.g. minimal change disease ({{ORGANIZATION}}), focal segmental glomerulosclerosis (FSGS) and membranous nephropathy ({{ORGANIZATION}}). These diseases are considered to be " diagnoses of exclusion," meaning they are diagnosed only after secondary causes have been excluded.
Secondary Nephrotic Syndrome is nephrotic syndrome that is associated with well-known kidney diseases like autoimmune disease like {{ORGANIZATION}} purpura, {{ORGANIZATION}} nephropathy, lupus nephritis etc. Secondary Nephrotic syndrome is also associated with post streptococcal glomerulonephritis, {{ORGANIZATION}}'s syndrome. It has also been associated with allergic reactions, drugs like NSAIDs, vaccination like the influenza and pneumococcal vaccines, tumors and viral infections.
A complete list of possible causes of nephrotic syndrome can be found here.