[Obstructive sleep apnea syndrome: an analysis of treatment in 450 patients].
OBJECTIVE
To explore the most appropriate treatment through comparing surgery, coblator plasma surgery (CPS) and nasal continuous positive airway pressure (nCPAP) in obstructive sleep apnea syndrome (OSAS).


METHOD
Four hundred and fifty cases were retrospectively analyzed, 368 patients were operated by uvuloplatopharyngoplasty (UPPP), partial excision of root of tongue and/or partial inferior turbinectomy. CPS were performed in 65 patients and 25 cases were accepted the nCPAP. Among them, 17 were the first selection and 8 were the second selection after operation failure.


RESULT
The outcomes of near-term (3-6 months) and long-term (1-3 years) in CPAP group are 95.23% and 83.33%, higher than surgery and CPS group. In the near-term result, surgery group is similar to CPS group (86.39% and 78.04%). The long-term effective of surgery group is lower than 50% and become worse with the time passed. And surgery may be accompanied with some dangerous and complications after operation. But the side effect in CPS and nCPAP is very little.


CONCLUSION
The treatment of OSAS is developing to safety, simple and acceptable. nCPAP and some simple safely surgery are fitted in serious patients. UPPP, CPS and nCPAP have good effect in light and middle patients. The long-term effect of CPS should still be observed in future.