Bilateral perysilvian polymicrogyria in Chiari I malformation.
CASE REPORT
We report on a 7-year-old girl with generalized epilepsy and mental retardation.


DISCUSSION
Neurologic examination was normal and only facial dysmorphic features, compatible with frontonasal dysplasia, were observed. However, magnetic resonance imaging (MRI) revealed Chiari I malformation together with bilateral opercular polymicrogyria. To our knowledge, this is the first report of the association of these developmental disorders. This condition raises questions regarding the ethiopathogenetic classification of Chiari spectrum and as to whether embryologic and genetic causes could be potentially interconnected.