<p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p> <p>Based on the analysis of the drafts of the human genome sequence, it is being speculated
that our species may possess an unexpectedly low number of genes. The quality of the
drafts, the impossibility of accurate gene prediction and the lack of sufficient transcript
sequence data, however, render such speculations very premature. The complexity of
human gene structure requires additional and extensive experimental verification of
transcripts that may result in major revisions of these early estimates of the number
of human genes.</p>
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Comp Funct Genomics. 2001 Jun; 2(3):169-175