<p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p> <p>Over recent years, there has been a growing interest in extracting information automatically
or semi-automatically from the scientific literature. This paper describes
a novel ontology-based interactive information extraction (OBIIE) framework and a
specific OBIIE system. We describe how this system enables life scientists to make
<italic>ad hoc</italic> queries similar to using a standard search engine, but where the results are
obtained in a database format similar to a pre-programmed information extraction
engine. We present a case study in which the system was evaluated for extracting
co-factors from EMBASE and MEDLINE.</p>
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Comp Funct Genomics. 2005 Feb-Mar; 6(1-2):67-71