<p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p> <p>Plasma fibronectin levels were measured in 33 patients with portal hypertension and c6mpared with
modified Child’s grading and a previously described prognostic index. Outcome at one year from blood
sampling was recorded.
Mean plasma fibronectin level was 304.1 mg/ml (sem 24.3) and significantly lower levels were found in
patients who had had a variceal bleed within the previous seven days. Plasma fibronectin levels tended
to be lower in patients with poor liver function as assessed by modified Child’s grading but this did not
achieve statistical significance.
Plasma fibronectin alone was not an accurate predictor of one year survival in these patients but only
one of seven patients who had a plasma fibronectin level below 300mg/l in association with a poor
prognostic index survived for one year.</p>
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HPB Surg. 1992; 5(4):229-234