<p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p> <p>Serum and urine total α-amylase isoenzymes values were estimated in two groups of patients, who
underwent either elective cholecystectomy and operative cholangiogram (group A — 59 patients) or
cholecystectomy without operative cholangiogram (group B — 68 patients). Serum and urine total α-amylase
and pancreatic isoamylase (p-type) values were statistically significantly increased within the
first 24 postoperative hours as compared to the preoperative levels only in group A (p &lt; 0.05). No
clinical signs of pancreatitis were observed. Serum lipase alterations did not reach any statistically
significant difference in either group. It is concluded that transient hyperamylasaemia after peroperative
cholangiogram may be due to a reversible chemical pancreatitis caused by the infused opacifying agent
into the common bile duct.</p>
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HPB Surg. 1990; 3(1):47-52