Background : Pressure sores are a major healthcare probLem which diminishes quaLity of[ife in al.l. aspects and causes dissatisfaction towards heaLth care process.Since pressure sores are prevent ab[e, it is considered as an indicator ofhealthcare qua[ity. Prevention requires systematic approach from patientadmission to discharge and involves the health care team, patients,caregivers and relatives.Objectives : To develop and determine effectiveness of pressure sore preventionprotocoL.Materia[ and Methods : During March 1st to JuLy 31st, 20L3, 4 steps were done:1) Gathering information, 2) protoco[ development, , pi[ot protocolimplementation, 4) protocol evaluation and improvement. MaLe patients15 years of age and over admitted to male Orthopedic ward, SurinhospitaI with Braden Sca[e Less than 76 for patients less than 70 years ofage and Less than 18 for patients over were included. Forteen nursesaLso participated. lnstruments include the draft protocoL, pressure soresurveillance form, repositioning and skin lesions record, pressure sorereporting form, evatuation form of the prevention protocol, and satisfaction questionnaire.Resutts : The protocol was implemened at admission, during admission, and atdischarge. Eighty-seven patients were enrolled, 8 developed pressuresores (9.2o/o) equating to 13.7:1,000 admission days. lmpLementation ofthe protocol reduced rate of pressure sores (p <0.05). Satisfaction was highfor both nurses G.7$.i, patients and reLatives (4.210.3).Conctusion : Development resuLted in a pressure sore prevention protocol implemented throughout aL|. stages of hospital admission. The protoco[ waspractical and satisfaction was high.