Bioimpedance a Diagnostic Tool for Tobacco Induced Oral Lesions: a Mixed Model cross-sectional study
<|reference_start|>Bioimpedance a Diagnostic Tool for Tobacco Induced Oral Lesions: a Mixed Model cross-sectional study: Introduction: Electrical impedance spectroscopy (EIS) has recently developed as a novel diagnostic device for screening and evaluating cervical dysplasia, prostate cancer, breast cancer and basal cell carcinoma. The current study aimed to validate and evaluate bioimpedance as a diagnostic tool for tobacco-induced oral lesions. Methodology: The study comprised 50 OSCC and OPMD tissue specimens for in-vitro study and 320 subjects for in vivo study. Bioimpedance device prepared and calibrated. EIS measurements were done for the habit and control groups and were compared. Results: The impedance value in the control group was significantly higher compared to the OPMD and OSCC groups. Diagnosis based on BIS measurements has a sensitivity of 95.9% and a specificity of 86.7%. Conclusion: Bioimpedance device can help in decision-making for differentiating OPMD and OSCC cases and their management, especially in primary healthcare settings.   Keywords: Impedance, Cancer, Diagnosis, Device, Community<|reference_end|>
@article{gupta2024bioimpedance,
    title={Bioimpedance a Diagnostic Tool for Tobacco Induced Oral Lesions: a Mixed
  Model cross-sectional study},
    author={Vaibhav Gupta, Poonam Goel, Usha Agrawal, Neena Chaudhary, Garima
  Jain, Deepak Gupta},
    journal={arXiv preprint arXiv:2408.11886},
    year={2024},
    archivePrefix={arXiv},
    eprint={2408.11886},
    primaryClass={q-bio.QM cs.CV}
}