Strategies of Loop Recombination in Ciliates
<|reference_start|>Strategies of Loop Recombination in Ciliates: Gene assembly in ciliates is an extremely involved DNA transformation process, which transforms a nucleus, the micronucleus, to another functionally different nucleus, the macronucleus. In this paper we characterize which loop recombination operations (one of the three types of molecular operations that accomplish gene assembly) can possibly be applied in the transformation of a given gene from its micronuclear form to its macronuclear form. We also characterize in which order these loop recombination operations are applicable. This is done in the abstract and more general setting of so-called legal strings.<|reference_end|>
@article{brijder2006strategies,
    title={Strategies of Loop Recombination in Ciliates},
    author={Robert Brijder, Hendrik Jan Hoogeboom, Michael Muskulus},
    journal={Discrete Applied Mathematics, v. 156, 1736-1753, 2008},
    year={2006},
    doi={10.1016/j.dam.2007.08.032},
    number={LIACS Technical Report 2006-01},
    archivePrefix={arXiv},
    eprint={cs/0601135},
    primaryClass={cs.LO q-bio.GN}
}