Exploring Multilingual Large Language Models for Enhanced TNM classification of Radiology Report in lung cancer staging
<|reference_start|>Exploring Multilingual Large Language Models for Enhanced TNM classification of Radiology Report in lung cancer staging: Background: Structured radiology reports remains underdeveloped due to labor-intensive structuring and narrative-style reporting. Deep learning, particularly large language models (LLMs) like GPT-3.5, offers promise in automating the structuring of radiology reports in natural languages. However, although it has been reported that LLMs are less effective in languages other than English, their radiological performance has not been extensively studied. Purpose: This study aimed to investigate the accuracy of TNM classification based on radiology reports using GPT3.5-turbo (GPT3.5) and the utility of multilingual LLMs in both Japanese and English. Material and Methods: Utilizing GPT3.5, we developed a system to automatically generate TNM classifications from chest CT reports for lung cancer and evaluate its performance. We statistically analyzed the impact of providing full or partial TNM definitions in both languages using a Generalized Linear Mixed Model. Results: Highest accuracy was attained with full TNM definitions and radiology reports in English (M = 94%, N = 80%, T = 47%, and ALL = 36%). Providing definitions for each of the T, N, and M factors statistically improved their respective accuracies (T: odds ratio (OR) = 2.35, p < 0.001; N: OR = 1.94, p < 0.01; M: OR = 2.50, p < 0.001). Japanese reports exhibited decreased N and M accuracies (N accuracy: OR = 0.74 and M accuracy: OR = 0.21). Conclusion: This study underscores the potential of multilingual LLMs for automatic TNM classification in radiology reports. Even without additional model training, performance improvements were evident with the provided TNM definitions, indicating LLMs' relevance in radiology contexts.<|reference_end|>
@article{matsuo2024exploring,
    title={Exploring Multilingual Large Language Models for Enhanced TNM
  classification of Radiology Report in lung cancer staging},
    author={Hidetoshi Matsuo, Mizuho Nishio, Takaaki Matsunaga, Koji Fujimoto,
  Takamichi Murakami},
    journal={Cancers 2024, 16(21), 3621},
    year={2024},
    doi={10.3390/cancers16213621},
    archivePrefix={arXiv},
    eprint={2406.06591},
    primaryClass={cs.CL cs.AI cs.LG}
}