Fully automated workflow for the design of patient-specific orthopaedic implants: application to total knee arthroplasty
<|reference_start|>Fully automated workflow for the design of patient-specific orthopaedic implants: application to total knee arthroplasty: Arthroplasty is commonly performed to treat joint osteoarthritis, reducing pain and improving mobility. While arthroplasty has known several technical improvements, a significant share of patients are still unsatisfied with their surgery. Personalised arthroplasty improves surgical outcomes however current solutions require delays, making it difficult to integrate in clinical routine. We propose a fully automated workflow to design patient-specific implants, presented for total knee arthroplasty, the most widely performed arthroplasty in the world nowadays.   The proposed pipeline first uses artificial neural networks to segment the proximal and distal extremities of the femur and tibia. Then the full bones are reconstructed using augmented statistical shape models, combining shape and landmarks information. Finally, 77 morphological parameters are computed to design patient-specific implants. The developed workflow has been trained using 91 CT scans of lower limb and evaluated on 41 CT scans manually segmented, in terms of accuracy and execution time.   The workflow accuracy was $0.4\pm0.2mm$ for the segmentation, $1.2\pm0.4mm$ for the full bones reconstruction, and $2.8\pm2.2mm$ for the anatomical landmarks determination. The custom implants fitted the patients' anatomy with $0.6\pm0.2mm$ accuracy. The whole process from segmentation to implants' design lasted about 5 minutes.   The proposed workflow allows for a fast and reliable personalisation of knee implants, directly from the patient CT image without requiring any manual intervention. It establishes a patient-specific pre-operative planning for TKA in a very short time making it easily available for all patients. Combined with efficient implant manufacturing techniques, this solution could help answer the growing number of arthroplasties while reducing complications and improving the patients' satisfaction.<|reference_end|>
@article{guezou-philippe2024fully,
    title={Fully automated workflow for the design of patient-specific orthopaedic
  implants: application to total knee arthroplasty},
    author={Aziliz Guezou-Philippe, Arnaud Clav'e, Ehouarn Maguet, Ludivine
  Maintier, Charles Garraud, Jean-Rassaire Fouefack, Val'erie Burdin, Eric
  Stindel, Guillaume Dardenne},
    journal={arXiv preprint arXiv:2403.15353},
    year={2024},
    archivePrefix={arXiv},
    eprint={2403.15353},
    primaryClass={cs.CV}
}