Kinematics of Abdominal Aortic Aneurysms
<|reference_start|>Kinematics of Abdominal Aortic Aneurysms: A search in Scopus within "Article title, Abstract, Keywords" unveils 2,444 documents focused on the biomechanics of Abdominal Aortic Aneurysm (AAA), mostly on AAA wall stress. Only 24 documents investigated AAA kinematics, an important topic that could potentially offer insights into the biomechanics of AAA. In this paper, we present an image-based approach for patient-specific, in vivo, and non-invasive AAA kinematic analysis using patient's time-resolved 3D computed tomography angiography (4D CTA) images. Our approach relies on regularized deformable image registration for estimating wall displacement, estimation of the local wall strain as the ratio of its normal displacement to its local radius of curvature, and local surface fitting with non-deterministic outlier detection for estimating the wall radius of curvature. We verified our approach against synthetic ground truth image data created by warping a 3D CTA image of AAA using a realistic displacement field obtained from a finite element biomechanical model. We applied our approach to assess AAA wall displacements and strains in ten patients. Our kinematic analysis results indicated that the 99th percentile of circumferential wall strain, among all patients, ranged from 3.16% to 7.31%, with an average of 5.36% and a standard deviation of 1.28%.<|reference_end|>
@article{jamshidian2024kinematics,
    title={Kinematics of Abdominal Aortic Aneurysms},
    author={Mostafa Jamshidian, Adam Wittek, Saeideh Sekhavat, Karol Miller},
    journal={arXiv preprint arXiv:2405.13377},
    year={2024},
    archivePrefix={arXiv},
    eprint={2405.13377},
    primaryClass={cs.CE}
}