Relation Extraction Using Large Language Models: A Case Study on Acupuncture Point Locations
<|reference_start|>Relation Extraction Using Large Language Models: A Case Study on Acupuncture Point Locations: In acupuncture therapy, the accurate location of acupoints is essential for its effectiveness. The advanced language understanding capabilities of large language models (LLMs) like Generative Pre-trained Transformers (GPT) present a significant opportunity for extracting relations related to acupoint locations from textual knowledge sources. This study aims to compare the performance of GPT with traditional deep learning models (Long Short-Term Memory (LSTM) and Bidirectional Encoder Representations from Transformers for Biomedical Text Mining (BioBERT)) in extracting acupoint-related location relations and assess the impact of pretraining and fine-tuning on GPT's performance. We utilized the World Health Organization Standard Acupuncture Point Locations in the Western Pacific Region (WHO Standard) as our corpus, which consists of descriptions of 361 acupoints. Five types of relations ('direction_of,' 'distance_of,' 'part_of,' 'near_acupoint,' and 'located_near') (n= 3,174) between acupoints were annotated. Five models were compared: BioBERT, LSTM, pre-trained GPT-3.5, fine-tuned GPT-3.5, as well as pre-trained GPT-4. Performance metrics included micro-average exact match precision, recall, and F1 scores. Our results demonstrate that fine-tuned GPT-3.5 consistently outperformed other models in F1 scores across all relation types. Overall, it achieved the highest micro-average F1 score of 0.92. This study underscores the effectiveness of LLMs like GPT in extracting relations related to acupoint locations, with implications for accurately modeling acupuncture knowledge and promoting standard implementation in acupuncture training and practice. The findings also contribute to advancing informatics applications in traditional and complementary medicine, showcasing the potential of LLMs in natural language processing.<|reference_end|>
@article{li2024relation,
    title={Relation Extraction Using Large Language Models: A Case Study on
  Acupuncture Point Locations},
    author={Yiming Li, Xueqing Peng, Jianfu Li, Xu Zuo, Suyuan Peng, Donghong Pei,
  Cui Tao, Hua Xu, Na Hong},
    journal={arXiv preprint arXiv:2404.05415},
    year={2024},
    doi={10.1093/jamia/ocae233},
    archivePrefix={arXiv},
    eprint={2404.05415},
    primaryClass={cs.CL cs.AI}
}