A: The variant NC_000020.11:g.59024223_59024225del in gene TUBB1 is classified as 'Likely_pathogenic' for Macrothrombocytopenia,_isolated,_1,_autosomal_dominant. Variant type: Deletion. Disease database links: MONDO:MONDO:0800047,MedGen:C5676892,OMIM:613112,Orphanet:140957. Review status: criteria provided, single submitter.