A: The variant NC_000021.9:g.37505443dup in gene DYRK1A is classified as 'Pathogenic' for not_provided|Complex_neurodevelopmental_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|MONDO:MONDO:0100038,MedGen:C5568766,Orphanet:528084. Review status: no assertion criteria provided.