A: The variant NC_000020.11:g.5314038A>C in gene PROKR2 is classified as 'Conflicting_classifications_of_pathogenicity' for Amenorrhea|not_provided|Hypogonadotropic_hypogonadism_3_with_or_without_anosmia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000141,MONDO:MONDO:0001836,MedGen:C0002453|MedGen:C3661900|MONDO:MONDO:0009482,MedGen:C3550478,OMIM:244200,Orphanet:478. Review status: no assertion criteria provided.