A: The variant NC_000019.10:g.38517691G>A in gene RYR1 is classified as 'Conflicting_classifications_of_pathogenicity' for Fetal_akinesia_deformation_sequence_1|Arthrogryposis_multiplex_congenita|Malignant_hyperthermia,_susceptibility_to,_1. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0001989,MONDO:MONDO:0100101,MedGen:C1276035,OMIM:208150,Orphanet:994|Human_Phenotype_Ontology:HP:0001389,Human_Phenotype_Ontology:HP:0001390,Human_Phenotype_Ontology:HP:0002759,Human_Phenotype_Ontology:HP:0002804,Human_Phenotype_Ontology:HP:0005188,Human_Phenotype_Ontology:HP:0005663,Human_Phenotype_Ontology:HP:0005809,Human_Phenotype_Ontology:HP:0005859,MONDO:MONDO:0015168,MeSH:D001176,MedGen:C5779613,OMIM:PS617468,Orphanet:1037|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423. Review status: criteria provided, conflicting classifications.