A: The variant NC_000022.11:g.25207069G>C in gene CRYBB3 is classified as 'Pathogenic' for Developmental_cataract|Cataract_22_multiple_types. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000519,Human_Phenotype_Ontology:HP:0001108,Human_Phenotype_Ontology:HP:0007679,Human_Phenotype_Ontology:HP:0007726,Human_Phenotype_Ontology:HP:0007788,MedGen:C0009691|MONDO:MONDO:0012336,MedGen:C1857853,OMIM:609741,Orphanet:91492. Review status: no assertion criteria provided.