A: The variant NC_000020.11:g.32807978C>G in gene DNMT3B is classified as 'Benign' for Immunodeficiency-centromeric_instability-facial_anomalies_syndrome_1. Molecular consequence: SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009454,MedGen:C4551557,OMIM:242860,Orphanet:2268. Review status: criteria provided, single submitter.