A: The variant NC_000020.11:g.36951653T>C in gene SAMHD1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_specified|Chilblain_lupus_2|not_provided|Aicardi-Goutieres_syndrome_5. Molecular consequence: SO:0001623: 5_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0013739,MedGen:C3280721,OMIM:614415|MedGen:C3661900|MONDO:MONDO:0013059,MedGen:C2749659,OMIM:612952,Orphanet:51. Review status: criteria provided, conflicting classifications.