A: The variant NC_000019.10:g.40396017C>T in gene PRX is classified as 'Uncertain_significance' for Charcot-Marie-Tooth_disease_type_4|Peripheral_neuropathy. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0018995,MedGen:C4082197,Orphanet:64749|Human_Phenotype_Ontology:HP:0003157,Human_Phenotype_Ontology:HP:0003407,Human_Phenotype_Ontology:HP:0007088,Human_Phenotype_Ontology:HP:0007235,Human_Phenotype_Ontology:HP:0007355,Human_Phenotype_Ontology:HP:0009830,MONDO:MONDO:0005244,MedGen:C0031117. Review status: criteria provided, multiple submitters, no conflicts.