A: The variant NC_000020.11:g.23049174C>T in gene THBD is classified as 'Uncertain_significance' for Atypical_hemolytic-uremic_syndrome_with_thrombomodulin_anomaly. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013044,MedGen:C2752036,OMIM:612926. Review status: criteria provided, single submitter.