A: The variant NC_000019.10:g.44907785G>A in gene APOE is classified as 'Likely_benign' for Alzheimer_disease_3|Alzheimer_disease_2|Alzheimer_disease_4|Lipoprotein_glomerulopathy|Sea-blue_histiocyte_syndrome|Familial_type_3_hyperlipoproteinemia|Age_related_macular_degeneration_1|Cardiovascular_phenotype|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011913,MedGen:C1843013,OMIM:607822,Orphanet:1020|MONDO:MONDO:0007089,MedGen:C1863051,OMIM:104310,Orphanet:1020|MONDO:MONDO:0011743,MedGen:C1847200,OMIM:606889,Orphanet:1020|MONDO:MONDO:0012725,MedGen:C2673196,OMIM:611771,Orphanet:329481|Human_Phenotype_Ontology:HP:0001982,MONDO:MONDO:0010017,MedGen:C0036489,OMIM:269600,Orphanet:158029|MONDO:MONDO:0018473,MedGen:C0020479,OMIM:617347,Orphanet:412|MONDO:MONDO:0011285,MedGen:C1864205,OMIM:603075|MedGen:CN230736|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.