A: The variant NC_000019.10:g.45364451C>T in gene ERCC2 is classified as 'Uncertain_significance' for Xeroderma_pigmentosum,_group_D|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010212,MedGen:C0268138,OMIM:278730|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.