A: The variant NC_000019.10:g.50413792G>A in gene POLD1 is classified as 'Conflicting_classifications_of_pathogenicity' for Polymerase_proofreading-related_adenomatous_polyposis|Colorectal_cancer,_susceptibility_to,_10|not_provided|Hereditary_cancer-predisposing_syndrome. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0018653,MedGen:C0130294,Orphanet:447877|MONDO:MONDO:0012953,MedGen:C2675481,OMIM:612591,Orphanet:220460|MedGen:C3661900|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162. Review status: criteria provided, conflicting classifications.