A: The variant NC_000022.11:g.20992858G>C in gene LZTR1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Noonan_syndrome_2|Noonan_syndrome_10. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0011531,MedGen:C1854469,OMIM:605275,Orphanet:648|MONDO:MONDO:0014693,MedGen:C4225280,OMIM:616564,Orphanet:648. Review status: criteria provided, conflicting classifications.