A: The variant NC_000019.10:g.15170746T>C in gene NOTCH3 is classified as 'Uncertain_significance' for Inborn_genetic_diseases|Pulmonary_arterial_hypertension. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|Human_Phenotype_Ontology:HP:0002092,Human_Phenotype_Ontology:HP:0006546,MONDO:MONDO:0015924,MeSH:D000081029,MedGen:C2973725,Orphanet:182090. Review status: criteria provided, single submitter.