A: The variant NC_000019.10:g.48233836_48233840del in gene CARD8 is classified as 'Uncertain_significance' for CARD8-related_disorder. Molecular consequence: SO:0001582: initiator_codon_variant,SO:0001589: frameshift_variant,SO:0001627: intron_variant. Variant type: Deletion. Disease database links: .. Review status: no assertion criteria provided.