A: The variant NC_000019.10:g.38516151G>A in gene RYR1 is classified as 'Uncertain_significance' for RYR1-related_disorder|RYR1-related_myopathy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN239331|MONDO:MONDO:0100150,MedGen:CN305348. Review status: criteria provided, multiple submitters, no conflicts.