A: The variant NC_000020.11:g.10663962C>T in gene JAG1 is classified as 'Pathogenic' for JAG1-related_disorder|not_provided|Alagille_syndrome_due_to_a_JAG1_point_mutation|Atypical_coarctation_of_aorta. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:C3661900|MONDO:MONDO:0016862,MedGen:C1956125,OMIM:118450,Orphanet:261619,Orphanet:52|MONDO:MONDO:0015446,MedGen:C3496579,Orphanet:1456. Review status: criteria provided, multiple submitters, no conflicts.