A: The variant NC_000019.10:g.18596902AC[1] in gene CRLF1 is classified as 'Pathogenic' for Cold-induced_sweating_syndrome_1. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Microsatellite. Disease database links: MONDO:MONDO:0010091,MedGen:C1848947,OMIM:272430,Orphanet:1545,Orphanet:157820. Review status: no assertion criteria provided.