A: The variant NC_000023.11:g.13760459G>A in gene OFD1 is classified as 'Uncertain_significance' for Bifid_nail|Abnormal_nail_morphology|Ridged_nail|Polydactyly,_postaxial,_type_A1|Retinitis_pigmentosa_23. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0010793,MedGen:C0544857|Human_Phenotype_Ontology:HP:0001597,MedGen:C0853087|Human_Phenotype_Ontology:HP:0001801,Human_Phenotype_Ontology:HP:0001807,Human_Phenotype_Ontology:HP:0001811,MedGen:C0423820|MONDO:MONDO:0008266,MedGen:C4282400,OMIM:174200|MONDO:MONDO:0010320,MedGen:C1419610,OMIM:300424,Orphanet:791. Review status: criteria provided, single submitter.