A: The variant NC_000020.11:g.45253001C>A in gene SLPI is classified as 'Pathogenic' for Otitis_media,_susceptibility_to. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0008162,MedGen:C1833692,OMIM:166760. Review status: criteria provided, single submitter.