A: The variant NC_000019.10:g.35039252A>C in gene SCN1B is classified as 'Uncertain_significance' for not_provided|Brugada_syndrome_5|Cardiovascular_phenotype|Atrial_fibrillation,_familial,_13|Generalized_epilepsy_with_febrile_seizures_plus,_type_1|Developmental_and_epileptic_encephalopathy,_52. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0013015,MedGen:C2748541,OMIM:612838,Orphanet:130,Orphanet:871|MedGen:CN230736|MONDO:MONDO:0014155,MedGen:C3809311,OMIM:615377|MONDO:MONDO:0011416,MedGen:C1858672,OMIM:604233,Orphanet:36387|MONDO:MONDO:0033361,MedGen:C4479236,OMIM:617350. Review status: criteria provided, multiple submitters, no conflicts.