A: The variant NC_000022.11:g.45541269C>T in gene FBLN1 is classified as 'Benign' for Synpolydactyly_type_2|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011984,MedGen:C1842422,OMIM:608180,Orphanet:295197,Orphanet:93403|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.