A: The variant NC_000021.9:g.34449543dup in gene KCNE1 is classified as 'Pathogenic' for Hereditary_hearing_loss_and_deafness|Long_QT_syndrome. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MedGen:C0236038|MONDO:MONDO:0002442,MeSH:D008133,MedGen:C0023976. Review status: no assertion criteria provided.