A: The variant NC_000021.9:g.44293094T>C in gene AIRE is classified as 'Benign' for not_provided|Polyglandular_autoimmune_syndrome,_type_1|not_specified. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0009411,MedGen:C0085859,OMIM:240300,Orphanet:3453|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.