A: The variant NC_000021.9:g.33818311G>A in gene ITSN1 is classified as 'Likely_pathogenic' for Neurodevelopmental_disorder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0700092,MeSH:D065886,MedGen:C1535926. Review status: criteria provided, single submitter.