A: The variant NC_000023.11:g.640836C>T in gene SHOX is classified as 'Pathogenic/Likely_pathogenic' for not_provided|Langer_mesomelic_dysplasia_syndrome|Leri-Weill_dyschondrosteosis. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0009588,MedGen:C0432230,OMIM:249700,Orphanet:2632|MONDO:MONDO:0007481,MedGen:C0265309,OMIM:127300,Orphanet:240. Review status: criteria provided, multiple submitters, no conflicts.