A: The variant NC_000021.9:g.46213822A>C in gene LSS is classified as 'Pathogenic' for Cataract_44. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014673,MedGen:C4225300,OMIM:616509,Orphanet:91492,Orphanet:98994. Review status: no assertion criteria provided.