A: The variant NC_000019.10:g.50413734G>A in gene POLD1 is classified as 'Benign/Likely_benign' for not_specified|not_provided|Colorectal_cancer,_susceptibility_to,_10|Familial_colorectal_cancer_type_X|Polymerase_proofreading-related_adenomatous_polyposis. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MedGen:C3661900|MONDO:MONDO:0012953,MedGen:C2675481,OMIM:612591,Orphanet:220460|MONDO:MONDO:0018604,MedGen:C3896578,Orphanet:440437|MONDO:MONDO:0018653,MedGen:C0130294,Orphanet:447877. Review status: criteria provided, multiple submitters, no conflicts.