A: The variant NC_000023.11:g.14845131C>T in gene FANCB is classified as 'Uncertain_significance' for VACTERL_association,_X-linked,_with_or_without_hydrocephalus|Fanconi_anemia_complementation_group_B. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010752,MedGen:C2931228,OMIM:314390,Orphanet:3412|MONDO:MONDO:0010351,MedGen:C1845292,OMIM:300514,Orphanet:84. Review status: criteria provided, single submitter.