A: The variant NC_000022.11:g.28694086C>T in gene CHEK2 is classified as 'Benign/Likely_benign' for not_provided|Hereditary_cancer-predisposing_syndrome|CHEK2-related_cancer_predisposition|Breast_and/or_ovarian_cancer|Familial_cancer_of_breast|Hereditary_breast_ovarian_cancer_syndrome|not_specified. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MONDO:MONDO:0700271,MedGen:C5882668,OMIM:609265,Orphanet:524|MedGen:CN221562|MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480,Orphanet:227535|MONDO:MONDO:0003582,MeSH:D061325,MedGen:C0677776,Orphanet:145|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.