A: The variant NC_000020.11:g.49005052G>A in gene ARFGEF2 is classified as 'Benign' for Periventricular_heterotopia_with_microcephaly,_autosomal_recessive|not_provided. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011966,MedGen:C1842563,OMIM:608097,Orphanet:2149|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.