A: The variant NC_000019.10:g.35746418G>C in gene PSENEN is classified as 'Pathogenic' for Acne_inversa,_familial,_2. Molecular consequence: SO:0001574: splice_acceptor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013397,MedGen:C3151037,OMIM:613736. Review status: no assertion criteria provided.