A: The variant NC_000021.9:g.43063032_43063033delinsAA in gene CBS is classified as 'Uncertain_significance' for Classic_homocystinuria|not_specified. Molecular consequence: SO:0001583: missense_variant. Variant type: Indel. Disease database links: MONDO:MONDO:0009352,MedGen:C0751202,OMIM:236200,Orphanet:394|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.