A: The variant NC_000021.9:g.45176080A>G in gene ADARB1 is classified as 'Pathogenic' for Neurodevelopmental_disorder_with_hypotonia,_microcephaly,_and_seizures. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030025,MedGen:C5394312,OMIM:618862. Review status: no assertion criteria provided.