A: The variant NC_000020.11:g.49524089C>T in gene PTGIS is classified as 'Likely_pathogenic' for Childhood-onset_schizophrenia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957430,MedGen:C0036346,Orphanet:641496. Review status: criteria provided, single submitter.