A: The variant NC_000022.11:g.46396724CA[2] in gene CELSR1 is classified as 'risk_factor' for Neural_tube_defects,_susceptibility_to. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Microsatellite. Disease database links: MONDO:MONDO:0020705,MedGen:C3891448,OMIM:182940. Review status: no assertion criteria provided.