A: The variant NC_000021.9:g.34880563C>A in gene RUNX1 is classified as 'Likely_pathogenic' for Clonal_Cytopenia_of_Undetermined_Significance|Hereditary_thrombocytopenia_and_hematologic_cancer_predisposition_syndrome|Pancytopenia. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MedGen:C5442191|MONDO:MONDO:0011071,MedGen:CN281654,Orphanet:71290|Human_Phenotype_Ontology:HP:0001876,MONDO:MONDO:0001529,MedGen:C0030312. Review status: reviewed by expert panel.