A: The variant NC_000019.10:g.15161009G>A in gene NOTCH3 is classified as 'Conflicting_classifications_of_pathogenicity' for Cerebral_arteriopathy,_autosomal_dominant,_with_subcortical_infarcts_and_leukoencephalopathy,_type_1|NOTCH3-related_disorder|Lateral_meningocele_syndrome|Myofibromatosis,_infantile,_2|Inborn_genetic_diseases|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0000914,MedGen:C4551768,OMIM:125310,Orphanet:136|.|MONDO:MONDO:0007537,MedGen:C1851710,OMIM:130720,Orphanet:2789|MONDO:MONDO:0014122,MedGen:C3809084,OMIM:615293,Orphanet:2591|MeSH:D030342,MedGen:C0950123|MedGen:C3661900. Review status: criteria provided, conflicting classifications.