A: The variant NC_000019.10:g.49861233G>A in gene PNKP is classified as 'Conflicting_classifications_of_pathogenicity' for Inborn_genetic_diseases|Microcephaly,_seizures,_and_developmental_delay|not_specified. Molecular consequence: SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0013254,MedGen:C3150667,OMIM:613402,Orphanet:1934|MedGen:CN169374. Review status: criteria provided, conflicting classifications.