A: The variant NC_000019.10:g.42355877G>A in gene MEGF8 is classified as 'Uncertain_significance' for Inborn_genetic_diseases|MEGF8-related_Carpenter_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0013998,MedGen:C3554247,OMIM:614976,Orphanet:65759. Review status: criteria provided, multiple submitters, no conflicts.