A: The variant NC_000019.10:g.49713465G>A in gene CPT1C is classified as 'Uncertain_significance' for Spastic_paraplegia. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0001258,Human_Phenotype_Ontology:HP:0007062,Human_Phenotype_Ontology:HP:0007124,Human_Phenotype_Ontology:HP:0007216,MedGen:C0037772. Review status: criteria provided, single submitter.