A: The variant NC_000021.9:g.44509277_44509278del in gene TSPEAR is classified as 'Pathogenic/Likely_pathogenic' for Inborn_genetic_diseases|not_provided|Ectodermal_dysplasia_14,_hair/tooth_type_with_or_without_hypohidrosis|TSPEAR-related_disorder. Molecular consequence: SO:0001589: frameshift_variant,SO:0001619: non-coding_transcript_variant. Variant type: Deletion. Disease database links: MeSH:D030342,MedGen:C0950123|MedGen:C3661900|MONDO:MONDO:0032584,MedGen:C4748560,OMIM:618180|.. Review status: criteria provided, multiple submitters, no conflicts.