A: The variant NC_000019.10:g.45352210C>T in gene ERCC2 is classified as 'Uncertain_significance' for Inborn_genetic_diseases|not_provided|not_specified|Xeroderma_pigmentosum. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|MedGen:C3661900|MedGen:CN169374|MONDO:MONDO:0019600,MedGen:C0043346,Orphanet:910. Review status: criteria provided, multiple submitters, no conflicts.