A: The variant NC_000020.11:g.34951850del in gene GSS is classified as 'Pathogenic/Likely_pathogenic' for Inherited_glutathione_synthetase_deficiency|Glutathione_synthetase_deficiency_with_5-oxoprolinuria|Glutathione_synthetase_deficiency_without_5-oxoprolinuria|not_provided. Molecular consequence: SO:0001582: initiator_codon_variant,SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0017909,MedGen:CN030166,Orphanet:32|Human_Phenotype_Ontology:HP:0003343,MONDO:MONDO:0009947,MedGen:C0398746,OMIM:266130,Orphanet:289846|MONDO:MONDO:0009284,MedGen:C1856399,OMIM:231900,Orphanet:289849,Orphanet:32|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.