A: The variant NC_000019.10:g.49183152C>T in gene TRPM4 is classified as 'Likely_benign' for Progressive_familial_heart_block_type_IB. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871. Review status: criteria provided, single submitter.