A: The variant NC_000020.11:g.58389311dup in gene VAPB is classified as 'Benign/Likely_benign' for not_provided|Amyotrophic_Lateral_Sclerosis,_Dominant|Spinal_Muscular_Atrophy,_Dominant. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant. Variant type: Duplication. Disease database links: MedGen:CN517202|MedGen:CN239175|MedGen:CN239253. Review status: criteria provided, multiple submitters, no conflicts.