A: The variant NC_000019.10:g.44908623dup in gene APOE is classified as 'Uncertain_significance' for not_provided|Familial_type_3_hyperlipoproteinemia. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|MONDO:MONDO:0018473,MedGen:C0020479,OMIM:617347,Orphanet:412. Review status: criteria provided, multiple submitters, no conflicts.