A: The variant NC_000021.9:g.42383201_42383202dup in gene TMPRSS3 is classified as 'Benign/Likely_benign' for not_provided|Hearing_loss,_autosomal_recessive|Autosomal_recessive_nonsyndromic_hearing_loss_8|not_specified. Molecular consequence: SO:0001574: splice_acceptor_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|MONDO:MONDO:0019588,MedGen:C1846647,OMIM:607197,OMIM:PS220290,Orphanet:90635,Orphanet:90636|MONDO:MONDO:0010987,MedGen:C1832827,OMIM:601072,Orphanet:90636|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.