A: The variant NC_000019.10:g.38506318G>A in gene RYR1 is classified as 'Uncertain_significance' for Central_core_myopathy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597. Review status: criteria provided, single submitter.