A: The variant NC_000022.11:g.46356865C>T in gene TRMU is classified as 'Likely_benign' for Acute_infantile_liver_failure_due_to_synthesis_defect_of_mtDNA-encoded_proteins|not_provided. Molecular consequence: SO:0001587: nonsense,SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013111,MedGen:C3278664,OMIM:613070,Orphanet:217371|MedGen:C3661900. Review status: criteria provided, single submitter.