A: The variant NC_000021.9:g.43053846C>T in gene CBS is classified as 'Benign/Likely_benign' for Classic_homocystinuria|not_specified. Molecular consequence: SO:0001624: 3_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009352,MedGen:C0751202,OMIM:236200,Orphanet:394|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.