A: The variant NC_000020.11:g.17988228C>T in gene MGME1 is classified as 'Benign/Likely_benign' for not_provided|Mitochondrial_DNA_depletion_syndrome_11|not_specified. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0014039,MedGen:C3554462,OMIM:615084,Orphanet:352447|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.