A: The variant NC_000020.11:g.4699627G>C in gene PRNP is classified as 'Uncertain_significance' for Huntington_disease-like_1. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011299,MedGen:C1864112,OMIM:603218,Orphanet:157941. Review status: criteria provided, single submitter.