A: The variant NC_000020.11:g.58891729G>T in gene GNAS is classified as 'Pathogenic' for Pseudohypoparathyroidism_type_I_A. Molecular consequence: SO:0001582: initiator_codon_variant,SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007078,MedGen:C3494506,OMIM:103580,Orphanet:79443. Review status: criteria provided, single submitter.