A: The variant NC_000020.11:g.35437778dup in gene GDF5 is classified as 'Pathogenic' for not_provided|GDF5-related_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|MedGen:CN169990. Review status: criteria provided, multiple submitters, no conflicts.