A: The variant NC_000022.11:g.17181552C>G in gene ADA2 is classified as 'Conflicting_classifications_of_pathogenicity' for Autoinflammatory_syndrome|not_provided|not_specified|Vasculitis_due_to_ADA2_deficiency|Sneddon_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0019751,MedGen:C3890737,Orphanet:93665|MedGen:C3661900|MedGen:CN169374|MONDO:MONDO:0014306,MedGen:C3887654,OMIM:615688,Orphanet:404553|MONDO:MONDO:0008436,MedGen:C0282492,OMIM:182410,Orphanet:820. Review status: criteria provided, conflicting classifications.