A: The variant NC_000019.10:g.54148402del in gene CNOT3 is classified as 'Likely_pathogenic' for Intellectual_developmental_disorder_with_speech_delay,_autism,_and_dysmorphic_facies. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0032864,MedGen:C5231456,OMIM:618672. Review status: criteria provided, single submitter.