A: The variant NC_000020.11:g.32434646dup in gene ASXL1 is classified as 'Pathogenic/Likely_pathogenic' for not_provided|ASXL1-related_disorder|Bohring-Opitz_syndrome|Abnormal_brain_morphology. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|.|MONDO:MONDO:0011510,MedGen:C0796232,OMIM:605039,Orphanet:97297|Human_Phenotype_Ontology:HP:0012443,MedGen:C4021085. Review status: criteria provided, multiple submitters, no conflicts. Oncogenicity: ONC: Oncogenic, ONCDISDB: Human_Phenotype_Ontology:HP:0002664,Human_Phenotype_Ontology:HP:0003008,Human_Phenotype_Ontology:HP:0006741,MONDO:MONDO:0005070,MeSH:D009369,MedGen:C0027651, ONCDN: Neoplasm, ONCREVSTAT: criteria_provided,_single_submitter, ONCSCV: SCV005872041