A: The variant NC_000022.11:g.20714458CTT[1] in gene PI4KA is classified as 'Pathogenic' for Spastic_paraplegia_84,_autosomal_recessive. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Microsatellite. Disease database links: MONDO:MONDO:0030482,MedGen:C5562025,OMIM:619621,Orphanet:631079. Review status: criteria provided, single submitter.