A: The variant NC_000022.11:g.28695780del in gene CHEK2 is classified as 'Likely_pathogenic' for Lynch_syndrome_1. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0007356,MedGen:C2936783,OMIM:120435,Orphanet:144. Review status: no assertion criteria provided.