A: The variant NC_000021.9:g.36936556G>A in gene HLCS is classified as 'Conflicting_classifications_of_pathogenicity' for Holocarboxylase_synthetase_deficiency|not_provided|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009666,MedGen:C0268581,OMIM:253270,Orphanet:79242|MedGen:C3661900|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, conflicting classifications.