A: The variant NC_000019.10:g.49818330A>G in gene MED25 is classified as 'Benign' for not_specified|Congenital_cataract-microcephaly-nevus_flammeus_simplex-severe_intellectual_disability_syndrome|not_provided|Charcot-Marie-Tooth_disease. Molecular consequence: SO:0001623: 5_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0014643,MedGen:C4225323,OMIM:616449,Orphanet:464738|MedGen:C3661900|MONDO:MONDO:0015626,MedGen:C0007959,OMIM:PS118220,Orphanet:166. Review status: criteria provided, multiple submitters, no conflicts.