A: The variant NC_000019.10:g.40395663G>A in gene PRX is classified as 'Pathogenic/Likely_pathogenic' for Charcot-Marie-Tooth_disease_type_4|Charcot-Marie-Tooth_disease,_type_I|Charcot-Marie-Tooth_disease_type_4F|Dejerine-Sottas_disease. Molecular consequence: SO:0001587: nonsense,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0018995,MedGen:C4082197,Orphanet:64749|MONDO:MONDO:0019011,MedGen:C0751036,Orphanet:65753|MONDO:MONDO:0013959,MedGen:C3540453,OMIM:614895,Orphanet:99952|MONDO:MONDO:0007790,MedGen:C0011195,OMIM:145900,Orphanet:64748. Review status: criteria provided, multiple submitters, no conflicts.