A: The variant NC_000022.11:g.28742240G>T in gene HSCB is classified as 'Uncertain_significance' for Anemia,_sideroblastic,_5. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030436,MedGen:C5561985,OMIM:619523. Review status: criteria provided, single submitter.