A: The variant NC_000020.11:g.23635271G>A in gene CST3 is classified as 'Conflicting_classifications_of_pathogenicity' for Hereditary_cerebral_amyloid_angiopathy,_Icelandic_type|CST3-related_Leukodystrophy|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007098,MedGen:C1527338,OMIM:105150,Orphanet:100008,Orphanet:85458|.|MedGen:C3661900. Review status: criteria provided, conflicting classifications.