A: The variant NC_000020.11:g.34560888del in gene PIGU is classified as 'Likely_pathogenic' for Glycosylphosphatidylinositol_biosynthesis_defect_21. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0032824,MedGen:C5231419,OMIM:618590. Review status: criteria provided, single submitter.