A: The variant NC_000022.11:g.41160675C>A in gene EP300 is classified as 'Benign/Likely_benign' for not_provided|Rubinstein-Taybi_syndrome_due_to_EP300_haploinsufficiency|EP300-related_disorder. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0013364,MedGen:C3150941,OMIM:613684,Orphanet:353284,Orphanet:783|.. Review status: criteria provided, multiple submitters, no conflicts.