A: The variant NC_000022.11:g.28719499G>A in gene CHEK2 is classified as 'Benign/Likely_benign' for CHEK2-related_cancer_predisposition|Hereditary_cancer-predisposing_syndrome|Malignant_tumor_of_breast|Familial_cancer_of_breast|not_specified|Hereditary_breast_ovarian_cancer_syndrome|not_provided. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0700271,MedGen:C5882668,OMIM:609265,Orphanet:524|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MONDO:MONDO:0007254,MedGen:C0006142|MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480,Orphanet:227535|MedGen:CN169374|MONDO:MONDO:0003582,MeSH:D061325,MedGen:C0677776,Orphanet:145|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.