A: The variant NC_000019.10:g.45396385_45396413del in gene PPP1R13L is classified as 'Pathogenic/Likely_pathogenic' for Arrhythmogenic_cardiomyopathy_with_variable_ectodermal_abnormalities|Primary_dilated_cardiomyopathy|Orofacial_cleft. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0957795,MedGen:C5882696,OMIM:620519|EFO:EFO_0000407,Human_Phenotype_Ontology:HP:0001644,Human_Phenotype_Ontology:HP:0001725,Human_Phenotype_Ontology:HP:0005159,Human_Phenotype_Ontology:HP:0200130,MONDO:MONDO:0005021,MeSH:D002311,MedGen:C0007193,Orphanet:217604|Human_Phenotype_Ontology:HP:0000202,MONDO:MONDO:0000358,MedGen:C3266076,OMIM:PS119530. Review status: criteria provided, multiple submitters, no conflicts.