A: The variant NC_000020.11:g.58440986CTT[1] in gene VAPB is classified as 'Conflicting_classifications_of_pathogenicity' for Spinal_Muscular_Atrophy,_Dominant|not_specified|Amyotrophic_Lateral_Sclerosis,_Dominant|not_provided|Amyotrophic_lateral_sclerosis_type_8|Adult-onset_proximal_spinal_muscular_atrophy,_autosomal_dominant|VAPB-related_disorder|Inborn_genetic_diseases. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant,SO:0001822: inframe_deletion. Variant type: Microsatellite. Disease database links: MedGen:CN239253|MedGen:CN169374|MedGen:CN239175|MedGen:C3661900|MONDO:MONDO:0012077,MedGen:C1837728,OMIM:608627,Orphanet:803|MONDO:MONDO:0008453,MedGen:C1854058,OMIM:182980,Orphanet:209335|.|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, conflicting classifications.