A: The variant NC_000022.11:g.40270242G>A in gene TNRC6B is classified as 'Uncertain_significance' for Global_developmental_delay_with_speech_and_behavioral_abnormalities. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030995,MedGen:C5543226,OMIM:619243. Review status: criteria provided, single submitter.