A: The variant NC_000022.11:g.42086239_42086240del in gene NDUFA6 is classified as 'Pathogenic' for Mitochondrial_complex_1_deficiency,_nuclear_type_33|Mitochondrial_disease. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0032636,MedGen:C4748840,OMIM:618253|MONDO:MONDO:0044970,MeSH:D028361,MedGen:C0751651,Orphanet:68380. Review status: no assertion criteria provided.