A: The variant NC_000020.11:g.2394520C>T in gene TGM6 is classified as 'Uncertain_significance' for Axial_muscle_stiffness|Myopathic_facies|Rigidity|Parkinsonian_disorder|Oculomotor_apraxia|Spinocerebellar_ataxia_type_35. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0006921,MedGen:C4024962|Human_Phenotype_Ontology:HP:0002058,Human_Phenotype_Ontology:HP:0004647,MedGen:C0332615|Human_Phenotype_Ontology:HP:0002063,MedGen:C0026837|Human_Phenotype_Ontology:HP:0001300,MONDO:MONDO:0021095,MedGen:C0242422|Human_Phenotype_Ontology:HP:0000628,Human_Phenotype_Ontology:HP:0000657,Human_Phenotype_Ontology:HP:0007764,MedGen:C3489733|MONDO:MONDO:0013485,MedGen:C3888031,OMIM:613908,Orphanet:276193. Review status: criteria provided, single submitter.