A: The variant NC_000019.10:g.17577430del in gene COLGALT1 is classified as 'Pathogenic' for Brain_small_vessel_disease_3. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0100105,MedGen:C5193053,OMIM:618360. Review status: no assertion criteria provided.