A: The variant NC_000019.10:g.39502999GCGGT[3] in gene DLL3 is classified as 'Pathogenic' for not_provided|Spondylocostal_dysostosis_1,_autosomal_recessive|Leukodystrophy_and_acquired_microcephaly_with_or_without_dystonia%3B. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Microsatellite. Disease database links: MedGen:C3661900|MONDO:MONDO:0020692,MedGen:CN032975,OMIM:277300,Orphanet:2311|MONDO:MONDO:0014766,MedGen:C4225213,OMIM:616763. Review status: criteria provided, multiple submitters, no conflicts.