A: The variant NC_000022.11:g.37226749A>G in gene RAC2 is classified as 'Uncertain_significance' for Neutrophil_immunodeficiency_syndrome|Immunodeficiency_73b_with_defective_neutrophil_chemotaxis_and_lymphopenia|Immunodeficiency_73c_with_defective_neutrophil_chemotaxis_and_hypogammaglobulinemia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011988,MedGen:C1842398,OMIM:608203,Orphanet:183707|MONDO:MONDO:0033554,MedGen:C5436549,OMIM:618986|MONDO:MONDO:0033555,MedGen:C5436550,OMIM:618987. Review status: criteria provided, single submitter.