A: The variant NC_000022.11:g.40280081_40280090del in gene TNRC6B is classified as 'Pathogenic' for Global_developmental_delay_with_speech_and_behavioral_abnormalities. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0030995,MedGen:C5543226,OMIM:619243. Review status: no assertion criteria provided.