A: The variant NC_000022.11:g.50721716GAG[1] in gene SHANK3 is classified as 'Uncertain_significance' for not_provided|Schizophrenia_15|Phelan-McDermid_syndrome. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Microsatellite. Disease database links: MedGen:C3661900|MONDO:MONDO:0013498,MedGen:C3151380,OMIM:613950|MONDO:MONDO:0011652,MedGen:C1853490,OMIM:606232,Orphanet:48652. Review status: criteria provided, single submitter.