A: The variant NC_000021.9:g.34792315GCC[3] in gene RUNX1 is classified as 'Uncertain_significance' for Hereditary_thrombocytopenia_and_hematologic_cancer_predisposition_syndrome|Hereditary_cancer-predisposing_syndrome. Molecular consequence: SO:0001821: inframe_insertion. Variant type: Microsatellite. Disease database links: MONDO:MONDO:0011071,MedGen:CN281654,Orphanet:71290|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162. Review status: reviewed by expert panel.