A: The variant NC_000020.11:g.36892061C>T in gene SAMHD1 is classified as 'Uncertain_significance' for Aicardi-Goutieres_syndrome_5|Chilblain_lupus_2. Molecular consequence: SO:0001624: 3_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013059,MedGen:C2749659,OMIM:612952,Orphanet:51|MONDO:MONDO:0013739,MedGen:C3280721,OMIM:614415. Review status: criteria provided, single submitter.