A: The variant NC_000022.11:g.28689200_28689204del in gene CHEK2 is classified as 'Likely_pathogenic' for Malignant_tumor_of_breast. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0007254,MedGen:C0006142. Review status: no assertion criteria provided.