A: The variant NC_000022.11:g.20996699C>G in gene LZTR1 is classified as 'Pathogenic/Likely_pathogenic' for Noonan_syndrome_10|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014693,MedGen:C4225280,OMIM:616564,Orphanet:648|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.