A: The variant NC_000021.9:g.44499878C>T in gene TSPEAR is classified as 'Conflicting_classifications_of_pathogenicity' for Autosomal_recessive_nonsyndromic_hearing_loss_98|not_provided|Ectodermal_dysplasia_14,_hair/tooth_type_with_or_without_hypohidrosis|Tooth_agenesis,_selective,_10|not_specified|TSPEAR-related_disorder|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013929,MedGen:C3553932,OMIM:614861,Orphanet:90636|MedGen:C3661900|MONDO:MONDO:0032584,MedGen:C4748560,OMIM:618180|MONDO:MONDO:0859339,MedGen:C5774277,OMIM:620173|MedGen:CN169374|.|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, conflicting classifications.