A: The variant NC_000022.11:g.50683332C>T in gene SHANK3 is classified as 'Benign/Likely_benign' for Schizophrenia_15|Phelan-McDermid_syndrome|not_provided. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013498,MedGen:C3151380,OMIM:613950|MONDO:MONDO:0011652,MedGen:C1853490,OMIM:606232,Orphanet:48652|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.