A: The variant NC_000019.10:g.18786145C>T in gene COMP is classified as 'Conflicting_classifications_of_pathogenicity' for Pseudoachondroplastic_spondyloepiphyseal_dysplasia_syndrome|Multiple_epiphyseal_dysplasia_type_1|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0008322,MedGen:C0410538,OMIM:177170,Orphanet:750|MONDO:MONDO:0007561,MedGen:C1838280,OMIM:132400,Orphanet:93308|MedGen:C3661900. Review status: criteria provided, conflicting classifications.