A: The variant NC_000022.11:g.28695764_28695768del in gene CHEK2 is classified as 'Pathogenic/Likely_pathogenic' for not_provided|Familial_cancer_of_breast. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MedGen:C3661900|MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480,Orphanet:227535. Review status: criteria provided, multiple submitters, no conflicts.