A: The variant NC_000021.9:g.44521921G>A in gene TSPEAR is classified as 'Conflicting_classifications_of_pathogenicity' for not_specified|not_provided|TSPEAR-related_disorder|Tooth_agenesis,_selective,_10|Ectodermal_dysplasia_14,_hair/tooth_type_with_or_without_hypohidrosis|Inborn_genetic_diseases. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MedGen:C3661900|.|MONDO:MONDO:0859339,MedGen:C5774277,OMIM:620173|MONDO:MONDO:0032584,MedGen:C4748560,OMIM:618180|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, conflicting classifications.