A: The variant NC_000020.11:g.10306165C>T in gene SNAP25 is classified as 'Likely_pathogenic' for Neurodevelopmental_disorder|Early_infantile_epileptic_encephalopathy_with_suppression_bursts|not_provided|SNAP25-related_disorder|SNAP25-related_early-onset_developmental_and_epileptic_encephalopathy|Congenital_myasthenic_syndrome_18. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0700092,MeSH:D065886,MedGen:C1535926|MONDO:MONDO:0100062,MedGen:C0393706,OMIM:PS308350,Orphanet:1934|MedGen:C3661900|.|.|MONDO:MONDO:0014590,MedGen:C4225364,OMIM:616330,Orphanet:590. Review status: criteria provided, multiple submitters, no conflicts.