A: The variant NC_000021.9:g.45486866C>T in gene COL18A1 is classified as 'Conflicting_classifications_of_pathogenicity' for COL18A1-related_disorder|not_specified|Knobloch_syndrome|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:CN169374|MONDO:MONDO:0800166,MedGen:C1849409,OMIM:PS267750,Orphanet:1571|MedGen:C3661900. Review status: criteria provided, conflicting classifications.