A: The variant NC_000021.9:g.34799310G>A in gene RUNX1 is classified as 'Pathogenic' for Hereditary_thrombocytopenia_and_hematological_cancer_predisposition_syndrome_associated_with_RUNX1|Hereditary_thrombocytopenia_and_hematologic_cancer_predisposition_syndrome|Thrombocytopenia|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0100083,MeSH:C563324,MedGen:C1832388,OMIM:601399,Orphanet:71290|MONDO:MONDO:0011071,MedGen:CN281654,Orphanet:71290|Human_Phenotype_Ontology:HP:0001873,Human_Phenotype_Ontology:HP:0001906,Human_Phenotype_Ontology:HP:0004838,Human_Phenotype_Ontology:HP:0008175,Human_Phenotype_Ontology:HP:0008268,Human_Phenotype_Ontology:HP:0008302,MONDO:MONDO:0002049,MeSH:D013921,MedGen:C0040034|MedGen:C3661900. Review status: reviewed by expert panel.