A: The variant NC_000021.9:g.33586090A>G in gene DONSON is classified as 'Pathogenic/Likely_pathogenic' for Microcephaly,_short_stature,_and_limb_abnormalities|Meier-Gorlin_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0060533,MedGen:C4539873,OMIM:617604,Orphanet:572773|MONDO:MONDO:0016817,MedGen:C1868684,OMIM:PS224690,Orphanet:2554. Review status: criteria provided, multiple submitters, no conflicts.