A: The variant NC_000022.11:g.28734715G>A in gene CHEK2 is classified as 'Conflicting_classifications_of_pathogenicity' for Hereditary_cancer|not_specified|Familial_cancer_of_breast|not_provided|CHEK2-related_cancer_predisposition|Hereditary_cancer-predisposing_syndrome|Breast_and/or_ovarian_cancer|Malignant_tumor_of_breast. Molecular consequence: SO:0001583: missense_variant,SO:0001623: 5_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C1333600|MedGen:CN169374|MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480,Orphanet:227535|MedGen:C3661900|MONDO:MONDO:0700271,MedGen:C5882668,OMIM:609265,Orphanet:524|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MedGen:CN221562|MONDO:MONDO:0007254,MedGen:C0006142. Review status: criteria provided, conflicting classifications.