A: The variant NC_000020.11:g.4699379C>T in gene PRNP is classified as 'Benign/Likely_benign' for Inherited_prion_disease|Huntington_disease-like_1|not_provided|Kuru,_susceptibility_to|Inherited_Creutzfeldt-Jakob_disease|Spongiform_encephalopathy_with_neuropsychiatric_features|Fatal_familial_insomnia|Gerstmann-Straussler-Scheinker_syndrome. Molecular consequence: SO:0001583: missense_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C5679775,Orphanet:280400|MONDO:MONDO:0011299,MedGen:C1864112,OMIM:603218,Orphanet:157941|MedGen:C3661900|MONDO:MONDO:0009500,MedGen:C1855588,OMIM:245300,Orphanet:454745|MONDO:MONDO:0007403,MedGen:C0751254,OMIM:123400,Orphanet:204,Orphanet:282166,Orphanet:454700|MONDO:MONDO:0011703,MedGen:C1847650,OMIM:606688|MONDO:MONDO:0010808,MedGen:C0206042,OMIM:600072,Orphanet:466|MONDO:MONDO:0007656,MedGen:C0017495,OMIM:137440,Orphanet:356. Review status: criteria provided, multiple submitters, no conflicts.