A: The variant NC_000022.11:g.45949993G>C in gene WNT7B is classified as 'Pathogenic' for Matthew-Wood_syndrome. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011010,MedGen:C1832661,OMIM:601186,Orphanet:2470. Review status: no assertion criteria provided.