A: The variant NC_000021.9:g.34449514del in gene KCNE1 is classified as 'Pathogenic' for Jervell_and_Lange-Nielsen_syndrome_1. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0024540,MedGen:C4551509,OMIM:220400,Orphanet:768,Orphanet:90647. Review status: criteria provided, single submitter.