A: The variant NC_000022.11:g.19764982T>C in gene TBX1 is classified as 'Uncertain_significance' for DiGeorge_syndrome|Velocardiofacial_syndrome|Tetralogy_of_Fallot. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0008564,MedGen:C0012236,OMIM:188400,Orphanet:567|MONDO:MONDO:0008644,MedGen:C0220704,OMIM:192430,Orphanet:567|Human_Phenotype_Ontology:HP:0001636,MONDO:MONDO:0008542,MedGen:C0039685,OMIM:187500,Orphanet:3303. Review status: criteria provided, single submitter.