A: The variant NC_000021.9:g.43063069_43063070insTCCAATGATCTGCAGAGGGCGCGGCTTCAGGGCTCAAGCCCAGCAAAAGCCCCACCTGGATGATCCAC in gene CBS is classified as 'Benign' for HYPERHOMOCYSTEINEMIA,_THROMBOTIC,_CBS-RELATED. Molecular consequence: SO:0001587: nonsense. Variant type: Insertion. Disease database links: MedGen:C3150344. Review status: criteria provided, single submitter.