A: The variant NC_000019.10:g.18868621_18868636dup in gene GDF1 is classified as 'Uncertain_significance' for Right_atrial_isomerism|Congenital_heart_defects,_multiple_types,_6. Molecular consequence: SO:0001587: nonsense,SO:0001624: 3_prime_UTR_variant. Variant type: Duplication. Disease database links: Human_Phenotype_Ontology:HP:0011536,MONDO:MONDO:0008832,MedGen:C3178806,OMIM:208530,Orphanet:97548|MONDO:MONDO:0013463,MedGen:C3151221,OMIM:613854,Orphanet:860. Review status: criteria provided, single submitter.