A: The variant NC_000020.11:g.59024621del in gene TUBB1 is classified as 'Likely_pathogenic' for Macrothrombocytopenia. Molecular consequence: SO:0001587: nonsense. Variant type: Deletion. Disease database links: Human_Phenotype_Ontology:HP:0040185,MedGen:C2751260. Review status: criteria provided, single submitter.