A: The variant NC_000021.9:g.42396077_42396078del in gene TMPRSS3 is classified as 'Uncertain_significance' for Hearing_loss,_autosomal_recessive. Variant type: Deletion. Disease database links: MONDO:MONDO:0019588,MedGen:C1846647,OMIM:607197,OMIM:PS220290,Orphanet:90635,Orphanet:90636. Review status: criteria provided, single submitter.