A: The variant NC_000020.11:g.49036004_49036006del in gene ARFGEF2 is classified as 'Uncertain_significance' for Periventricular_laminar_heterotopia. Molecular consequence: SO:0001624: 3_prime_UTR_variant. Variant type: Deletion. Disease database links: Human_Phenotype_Ontology:HP:0032389,MedGen:C2678104. Review status: criteria provided, single submitter.