A: The variant NC_000020.11:g.4699709C>G in gene PRNP is classified as 'Pathogenic' for CEREBRAL_AMYLOID_ANGIOPATHY,_PRNP-RELATED. Molecular consequence: SO:0001587: nonsense,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3805618. Review status: no assertion criteria provided.