A: The variant NC_000019.10:g.44908793TCC[1] in gene APOE is classified as 'Pathogenic' for not_provided|Cardiovascular_phenotype|APOE-related_disorder|Sea-blue_histiocyte_syndrome. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Microsatellite. Disease database links: MedGen:C3661900|MedGen:CN230736|.|Human_Phenotype_Ontology:HP:0001982,MONDO:MONDO:0010017,MedGen:C0036489,OMIM:269600,Orphanet:158029. Review status: criteria provided, multiple submitters, no conflicts.