A: The variant NC_000019.10:g.29702737dup in gene C19orf12 is classified as 'Pathogenic' for Spastic_ataxia. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Duplication. Disease database links: Human_Phenotype_Ontology:HP:0002497,MONDO:MONDO:0017845,MedGen:C1849156,OMIM:PS108600,Orphanet:316226. Review status: criteria provided, single submitter.