A: The variant NC_000022.11:g.28696941T>A in gene CHEK2 is classified as 'Uncertain_significance' for Familial_prostate_cancer. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0700275,MedGen:C2931456,OMIM:176807,Orphanet:1331. Review status: criteria provided, single submitter.