A: The variant NC_000020.11:g.10412781C>T in gene MKKS is classified as 'Uncertain_significance' for MKKS-related_disorder|Bardet-Biedl_syndrome|McKusick-Kaufman_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: .|MONDO:MONDO:0015229,MedGen:C0752166,OMIM:PS209900,Orphanet:110|MONDO:MONDO:0009367,MedGen:C0948368,OMIM:236700,Orphanet:2473. Review status: criteria provided, single submitter.