A: The variant NC_000022.11:g.28689174del in gene CHEK2 is classified as 'Likely_pathogenic' for Breast_neoplasm. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: Human_Phenotype_Ontology:HP:0010623,Human_Phenotype_Ontology:HP:0100013,MONDO:MONDO:0021100,MeSH:D001943,MedGen:C1458155. Review status: no assertion criteria provided.