A: The variant NC_000020.11:g.44620380_44620381del in gene ADA is classified as 'Pathogenic/Likely_pathogenic' for not_provided|Severe_combined_immunodeficiency,_autosomal_recessive,_T_cell-negative,_B_cell-negative,_NK_cell-negative,_due_to_adenosine_deaminase_deficiency|Severe_combined_immunodeficiency_disease. Molecular consequence: SO:0001589: frameshift_variant,SO:0001619: non-coding_transcript_variant. Variant type: Deletion. Disease database links: MedGen:C3661900|MONDO:MONDO:0007064,MedGen:C1863236,OMIM:102700,Orphanet:277|Human_Phenotype_Ontology:HP:0004430,MONDO:MONDO:0015974,MeSH:D016511,MedGen:C0085110,Orphanet:183660. Review status: criteria provided, multiple submitters, no conflicts.