A: The variant NC_000020.11:g.59023906C>T in gene TUBB1 is classified as 'Uncertain_significance' for Congenital_hypothyroidism|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000851,MONDO:MONDO:0018612,MedGen:C0010308,Orphanet:442|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.