A: The variant NC_000020.11:g.59301619_59301620delinsT in gene EDN3 is classified as 'Pathogenic' for Waardenburg_syndrome_type_4B. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Indel. Disease database links: MONDO:MONDO:0013201,MedGen:C2750457,OMIM:613265,Orphanet:897. Review status: no assertion criteria provided.