A: The variant NC_000019.10:g.42249594_42249598dup in gene ERF is classified as 'Likely_pathogenic' for Craniosynostosis_4. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: Human_Phenotype_Ontology:HP:0004443,Human_Phenotype_Ontology:HP:0004486,MONDO:MONDO:0010929,MedGen:C1833340,OMIM:600775. Review status: criteria provided, single submitter.