A: The variant NC_000021.9:g.44296463C>T in gene AIRE is classified as 'Likely_benign' for Polyglandular_autoimmune_syndrome,_type_1. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009411,MedGen:C0085859,OMIM:240300,Orphanet:3453. Review status: criteria provided, single submitter.