A: The variant NC_000019.10:g.35125506A>T in gene LGI4 is classified as 'Pathogenic' for Arthrogryposis_multiplex_congenita_1,_neurogenic,_with_myelin_defect. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0060486,MedGen:C4479539,OMIM:617468. Review status: no assertion criteria provided.