A: The variant NC_000021.9:g.39277339A>G in gene BRWD1 is classified as 'Uncertain_significance' for Recurrent_sinusitis|Situs_inversus|Bronchiectasis|Male_infertility. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0011108,MedGen:C0581354|Human_Phenotype_Ontology:HP:0001696,MONDO:MONDO:0010029,MedGen:C4551493,Orphanet:101063|Human_Phenotype_Ontology:HP:0002110,MONDO:MONDO:0004822,MedGen:C0006267,OMIM:PS211400|Human_Phenotype_Ontology:HP:0003251,MONDO:MONDO:0005372,MedGen:C0021364. Review status: no assertion criteria provided.