A: The variant NC_000020.11:g.32787256G>A in gene DNMT3B is classified as 'Likely_benign' for not_provided|Centromeric_instability_of_chromosomes_1,9_and_16_and_immunodeficiency. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0000133,MedGen:C0398788,OMIM:PS242860,Orphanet:2268. Review status: criteria provided, multiple submitters, no conflicts.