A: The variant NC_000020.11:g.17969914_17969916del in gene MGME1 is classified as 'Uncertain_significance' for Mitochondrial_DNA_depletion_syndrome_11|not_provided. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MONDO:MONDO:0014039,MedGen:C3554462,OMIM:615084,Orphanet:352447|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.