A: The variant NC_000019.10:g.38517498C>T in gene RYR1 is classified as 'Conflicting_classifications_of_pathogenicity' for Central_core_myopathy|Congenital_multicore_myopathy_with_external_ophthalmoplegia|Malignant_hyperthermia,_susceptibility_to,_1|RYR1-related_disorder|Neuromuscular_disease,_congenital,_with_uniform_type_1_fiber. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|Human_Phenotype_Ontology:HP:0003789,Human_Phenotype_Ontology:HP:0003804,MONDO:MONDO:0009712,MedGen:C1850674,OMIM:255320,Orphanet:598,Orphanet:98905|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|MedGen:CN239331|MedGen:C2674259. Review status: criteria provided, conflicting classifications.