A: The variant NC_000021.9:g.31667298G>C in gene SOD1 is classified as 'Pathogenic' for Amyotrophic_lateral_sclerosis_type_1|Motor_neuron_disease. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803|MONDO:MONDO:0020128,MedGen:C0085084,Orphanet:98503. Review status: criteria provided, multiple submitters, no conflicts.