A: The variant NC_000020.11:g.33748949G>A in gene ZNF341 is classified as 'Benign' for not_provided|Hyper-IgE_recurrent_infection_syndrome_3,_autosomal_recessive|ZNF341-related_disorder. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0032654,MedGen:C4748969,OMIM:618282|.. Review status: criteria provided, multiple submitters, no conflicts.