A: The variant NC_000019.10:g.41386724A>T in gene EXOSC5 is classified as 'Pathogenic' for Cerebellar_ataxia,_brain_abnormalities,_and_cardiac_conduction_defects. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0859200,MedGen:C5562005,OMIM:619576,Orphanet:641361. Review status: no assertion criteria provided.