A: The variant NC_000019.10:g.52211389C>T in gene PPP2R1A is classified as 'Likely_pathogenic' for Houge-Janssens_syndrome_2. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014605,MedGen:C4225352,OMIM:616362,Orphanet:457284. Review status: criteria provided, single submitter. Oncogenicity: ONC: Uncertain_significance, ONCDISDB: Human_Phenotype_Ontology:HP:0002664,Human_Phenotype_Ontology:HP:0003008,Human_Phenotype_Ontology:HP:0006741,MONDO:MONDO:0005070,MeSH:D009369,MedGen:C0027651, ONCDN: Neoplasm, ONCREVSTAT: criteria_provided,_single_submitter, ONCSCV: SCV005872040