A: The variant NC_000019.10:g.18869181del in gene GDF1 is classified as 'Uncertain_significance' for Congenital_heart_defects,_multiple_types,_6. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0013463,MedGen:C3151221,OMIM:613854,Orphanet:860. Review status: criteria provided, single submitter.