A: The variant NC_000021.9:g.33914447T>C in gene ATP5PO is classified as 'Pathogenic/Likely_pathogenic' for Mitochondrial_complex_V_(ATP_synthase)_deficiency,_nuclear_type_7|ATP5PO-related_disorder|Leigh_syndrome. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957255,MedGen:C5830482,OMIM:620359|.|MONDO:MONDO:0009723,MedGen:C2931891,OMIM:256000,Orphanet:506. Review status: criteria provided, multiple submitters, no conflicts.