A: The variant NC_000020.11:g.59324607_59324608del in gene EDN3 is classified as 'Conflicting_classifications_of_pathogenicity' for Hirschsprung_Disease,_Dominant|Waardenburg_syndrome|not_provided. Molecular consequence: SO:0001624: 3_prime_UTR_variant. Variant type: Deletion. Disease database links: MedGen:CN239304|MONDO:MONDO:0018094,MedGen:C3266898,OMIM:PS193500,Orphanet:3440|MedGen:C3661900. Review status: criteria provided, conflicting classifications.