A: The variant NC_000022.11:g.41524861G>A in gene ACO2 is classified as 'Uncertain_significance' for Inborn_genetic_diseases|not_provided|Mitochondrial_disease. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|MedGen:C3661900|MONDO:MONDO:0044970,MeSH:D028361,MedGen:C0751651,Orphanet:68380. Review status: criteria provided, multiple submitters, no conflicts.