A: The variant NC_000020.11:g.49374604G>A in gene KCNB1 is classified as 'Pathogenic/Likely_pathogenic' for Developmental_and_epileptic_encephalopathy,_26|not_provided|Early_infantile_epileptic_encephalopathy_with_suppression_bursts. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014477,MedGen:C4015119,OMIM:616056,Orphanet:442835|MedGen:C3661900|MONDO:MONDO:0100062,MedGen:C0393706,OMIM:PS308350,Orphanet:1934. Review status: criteria provided, multiple submitters, no conflicts.