A: The variant NC_000019.10:g.42248850G>A in gene ERF is classified as 'Likely_benign' for TWIST1-related_craniosynostosis|Chitayat_syndrome|Craniosynostosis_4|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007399,MedGen:C4551902,OMIM:123100,Orphanet:63440|MONDO:MONDO:0014956,MedGen:C4310679,OMIM:617180|Human_Phenotype_Ontology:HP:0004443,Human_Phenotype_Ontology:HP:0004486,MONDO:MONDO:0010929,MedGen:C1833340,OMIM:600775|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, multiple submitters, no conflicts.