A: The variant NC_000021.9:g.44521934C>T in gene TSPEAR is classified as 'Likely_benign' for not_specified|TSPEAR-related_disorder|not_provided|Ectodermal_dysplasia_14,_hair/tooth_type_with_or_without_hypohidrosis|Autosomal_recessive_nonsyndromic_hearing_loss_98. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|.|MedGen:C3661900|MONDO:MONDO:0032584,MedGen:C4748560,OMIM:618180|MONDO:MONDO:0013929,MedGen:C3553932,OMIM:614861,Orphanet:90636. Review status: criteria provided, multiple submitters, no conflicts.