A: The variant NC_000022.11:g.20988783C>G in gene LZTR1 is classified as 'Conflicting_classifications_of_pathogenicity' for Noonan_syndrome_2|LZTR1-related_schwannomatosis|Noonan_syndrome_10|not_provided|Cardiovascular_phenotype|Hereditary_cancer-predisposing_syndrome. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011531,MedGen:C1854469,OMIM:605275,Orphanet:648|MONDO:MONDO:0014299,MedGen:C3810283,OMIM:615670,Orphanet:93921|MONDO:MONDO:0014693,MedGen:C4225280,OMIM:616564,Orphanet:648|MedGen:C3661900|MedGen:CN230736|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162. Review status: criteria provided, conflicting classifications.