A: The variant NC_000021.9:g.42486410T>C in gene RSPH1 is classified as 'Uncertain_significance' for Primary_ciliary_dyskinesia|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0012265,MONDO:MONDO:0016575,MedGen:C0008780,OMIM:PS244400,Orphanet:244|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, multiple submitters, no conflicts.