A: The variant NC_000019.10:g.41906487C>T in gene ARHGEF1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_specified|Immunodeficiency_62|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0032763,MedGen:C5193109,OMIM:618459|MedGen:C3661900. Review status: criteria provided, conflicting classifications.