A: The variant NC_000019.10:g.42295143dup in gene CIC is classified as 'Uncertain_significance' for NK-cell_enteropathy|not_specified|Intellectual_disability,_autosomal_dominant_45. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0016996,MedGen:C4509932,Orphanet:263665|MedGen:CN169374|MONDO:MONDO:0030910,MedGen:C4539848,OMIM:617600. Review status: criteria provided, single submitter.