A: The variant NC_000020.11:g.5955247A>C in gene MCM8 is classified as 'Likely_pathogenic' for Premature_ovarian_failure_10|Azoospermia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0044776,MedGen:C4225402,OMIM:612885|Human_Phenotype_Ontology:HP:0000027,MONDO:MONDO:0100459,MeSH:D053713,MedGen:C0004509. Review status: criteria provided, single submitter.