A: The variant NC_000019.10:g.50417280_50417287del in gene POLD1 is classified as 'Likely_benign' for Colorectal_cancer,_susceptibility_to,_10|Polymerase_proofreading-related_adenomatous_polyposis. Molecular consequence: SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0012953,MedGen:C2675481,OMIM:612591,Orphanet:220460|MONDO:MONDO:0018653,MedGen:C0130294,Orphanet:447877. Review status: criteria provided, multiple submitters, no conflicts.