A: The variant NC_000019.10:g.50908596C>T in gene KLK4 is classified as 'Likely_pathogenic' for not_provided|Amelogenesis_imperfecta_type_2A1. Molecular consequence: SO:0001587: nonsense,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0008772,MedGen:C2673922,OMIM:204700,Orphanet:88661. Review status: criteria provided, multiple submitters, no conflicts.