A: The variant NC_000020.11:g.40688745G>C in gene MAFB is classified as 'Uncertain_significance' for Duane_retraction_syndrome_3_with_or_without_deafness|Multicentric_carpo-tarsal_osteolysis_with_or_without_nephropathy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014880,MedGen:C4310752,OMIM:617041,Orphanet:233|MONDO:MONDO:0008152,MedGen:C2674705,OMIM:166300,Orphanet:2774. Review status: criteria provided, single submitter.