A: The variant NC_000021.9:g.45477887G>A in gene COL18A1 is classified as 'Benign' for not_specified|Knobloch_syndrome|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0800166,MedGen:C1849409,OMIM:PS267750,Orphanet:1571|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.