A: The variant NC_000020.11:g.34393897A>G in gene ITCH is classified as 'Likely_benign' for Syndromic_multisystem_autoimmune_disease_due_to_ITCH_deficiency. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013245,MedGen:C3150649,OMIM:613385,Orphanet:228426. Review status: criteria provided, single submitter.