A: The variant NC_000020.11:g.18473413C>T in gene POLR3F is classified as 'Pathogenic' for Immunodeficiency_101_(varicella_zoster_virus-specific). Molecular consequence: SO:0001587: nonsense,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030813,MedGen:C5676983,OMIM:619872. Review status: no assertion criteria provided.