A: The variant NC_000022.11:g.32498225A>T in gene FBXO7 is classified as 'Uncertain_significance' for Parkinsonian-pyramidal_syndrome|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009830,MedGen:C1850100,OMIM:260300,Orphanet:171695|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, multiple submitters, no conflicts.