A: The variant NC_000019.10:g.50399370G>C in gene POLD1 is classified as 'Uncertain_significance' for Colorectal_cancer,_susceptibility_to,_10. Molecular consequence: SO:0001574: splice_acceptor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0012953,MedGen:C2675481,OMIM:612591,Orphanet:220460. Review status: criteria provided, single submitter.