A: The variant NC_000021.9:g.43066352C>T in gene CBS is classified as 'Likely_benign' for HYPERHOMOCYSTEINEMIA,_THROMBOTIC,_CBS-RELATED|not_provided|Cardiovascular_phenotype. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3150344|MedGen:C3661900|MedGen:CN230736. Review status: criteria provided, multiple submitters, no conflicts.