A: The variant NC_000019.10:g.45768830A>C in gene SIX5 is classified as 'Likely_benign' for Branchiootorenal_syndrome_2|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0012575,MedGen:C1970479,OMIM:610896,Orphanet:107|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.