A: The variant NC_000021.9:g.43063086G>C in gene CBS is classified as 'Likely_benign' for Classic_homocystinuria|HYPERHOMOCYSTEINEMIA,_THROMBOTIC,_CBS-RELATED. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009352,MedGen:C0751202,OMIM:236200,Orphanet:394|MedGen:C3150344. Review status: criteria provided, single submitter.