A: The variant NC_000022.11:g.35386918C>T in gene HMOX1 is classified as 'Benign/Likely_benign' for not_provided|Heme_oxygenase_1_deficiency|COPD,_severe_early_onset|HMOX1-related_disorder. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0013536,MedGen:C1841651,OMIM:614034,Orphanet:562509|MONDO:MONDO:0011751,MedGen:C1847014|.. Review status: criteria provided, multiple submitters, no conflicts.