A: The variant NC_000021.9:g.44504784A>T in gene TSPEAR is classified as 'Uncertain_significance' for not_specified|Ectodermal_dysplasia_14,_hair/tooth_type_with_or_without_hypohidrosis. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0032584,MedGen:C4748560,OMIM:618180. Review status: criteria provided, single submitter.