A: The variant NC_000020.11:g.49248055_49248058delinsGA in gene ZNFX1 is classified as 'Likely_pathogenic' for Immunodeficiency_91_and_hyperinflammation. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Indel. Disease database links: MONDO:MONDO:0030491,MedGen:C5562073,OMIM:619644. Review status: criteria provided, single submitter.