A: The variant NC_000019.10:g.40613164G>A in gene LTBP4 is classified as 'Uncertain_significance' for Cutis_laxa_with_severe_pulmonary,_gastrointestinal_and_urinary_anomalies. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013170,MedGen:C2750804,OMIM:613177,Orphanet:221145. Review status: criteria provided, single submitter.