A: The variant NC_000021.9:g.36461657_36461658insCACGGCCGTGCACCATG in gene CLDN14 is classified as 'Pathogenic' for Sensorineural_hearing_loss_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Insertion. Disease database links: Human_Phenotype_Ontology:HP:0000374,Human_Phenotype_Ontology:HP:0000407,Human_Phenotype_Ontology:HP:0001753,Human_Phenotype_Ontology:HP:0001916,Human_Phenotype_Ontology:HP:0008538,Human_Phenotype_Ontology:HP:0008553,Human_Phenotype_Ontology:HP:0008565,Human_Phenotype_Ontology:HP:0008576,Human_Phenotype_Ontology:HP:0008611,Human_Phenotype_Ontology:HP:0008613,Human_Phenotype_Ontology:HP:0008614,MONDO:MONDO:0020678,MeSH:D006319,MedGen:C0018784. Review status: criteria provided, single submitter.