A: The variant NC_000019.10:g.40692223C>A in gene COQ8B is classified as 'Pathogenic/Likely_pathogenic' for Nephrotic_syndrome,_type_9. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014257,MedGen:C3809965,OMIM:615573,Orphanet:656. Review status: criteria provided, multiple submitters, no conflicts.