A: The variant NC_000019.10:g.38525492G>A in gene RYR1 is classified as 'Likely_benign' for RYR1-related_myopathy|RYR1-related_disorder|Central_core_myopathy|Malignant_hyperthermia,_susceptibility_to,_1|not_provided|not_specified|Malignant_hyperthermia_of_anesthesia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0100150,MedGen:CN305348|MedGen:CN239331|MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|MedGen:C3661900|MedGen:CN169374|Human_Phenotype_Ontology:HP:0034733,MONDO:MONDO:0018493,MedGen:C0024591,Orphanet:423. Review status: reviewed by expert panel.