A: The variant NC_000020.11:g.46560194C>T in gene SLC13A3 is classified as 'Uncertain_significance' for Prostate_cancer|not_provided|Leukoencephalopathy,_acute_reversible,_with_increased_urinary_alpha-ketoglutarate. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0012125,MONDO:MONDO:0008315,MedGen:C0376358,Orphanet:1331|MedGen:C3661900|MONDO:MONDO:0032716,MedGen:C5193068,OMIM:618384,Orphanet:615964. Review status: criteria provided, multiple submitters, no conflicts.