A: The variant NC_000020.11:g.35434273del in gene GDF5 is classified as 'Pathogenic/Likely_pathogenic' for not_provided|Grebe_syndrome. Molecular consequence: SO:0001589: frameshift_variant,SO:0001619: non-coding_transcript_variant. Variant type: Deletion. Disease database links: MedGen:C3661900|MONDO:MONDO:0008703,MedGen:C0265260,OMIM:200700,Orphanet:2098. Review status: criteria provided, multiple submitters, no conflicts.