A: The variant NC_000019.10:g.18156039G>A in gene PIK3R2 is classified as 'Benign' for PIK3R2-related_disorder|not_specified|not_provided|Megalencephaly-polymicrogyria-polydactyly-hydrocephalus_syndrome_1|Overgrowth_syndrome_and/or_cerebral_malformations_due_to_abnormalities_in_MTOR_pathway_genes. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:CN169374|MedGen:C3661900|MONDO:MONDO:0011313,MedGen:C4012727,OMIM:603387,Orphanet:83473|MONDO:MONDO:0100283,MedGen:CN300503. Review status: reviewed by expert panel.