A: The variant NC_000022.11:g.37510258T>G in gene CARD10 is classified as 'Uncertain_significance' for Immunodeficiency_89_and_autoimmunity. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030484,MedGen:C5562027,OMIM:619632. Review status: criteria provided, single submitter.