A: The variant NC_000020.11:g.10645376_10645377insC in gene JAG1 is classified as 'Likely_pathogenic' for Atypical_coarctation_of_aorta. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Insertion. Disease database links: MONDO:MONDO:0015446,MedGen:C3496579,Orphanet:1456. Review status: no assertion criteria provided.