A: The variant NC_000019.10:g.41344806_41344812del in gene TGFB1 is classified as 'Likely_pathogenic' for Inflammatory_bowel_disease,_immunodeficiency,_and_encephalopathy. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0032601,MedGen:C4748708,OMIM:618213,Orphanet:565788. Review status: criteria provided, single submitter.