A: The variant NC_000022.11:g.37069308_37069309dup in gene TMPRSS6 is classified as 'Pathogenic' for Iron-refractory_iron_deficiency_anemia. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0008788,MedGen:C0085576,OMIM:206200,Orphanet:209981. Review status: no assertion criteria provided.