A: The variant NC_000022.11:g.39663716_39663720del in gene CACNA1I is classified as 'Pathogenic' for Neurodevelopmental_disorder_with_speech_impairment_and_with_or_without_seizures. Molecular consequence: SO:0001574: splice_acceptor_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0859313,MedGen:C5774252,OMIM:620114. Review status: no assertion criteria provided.