A: The variant NC_000022.11:g.28719496_28719500del in gene CHEK2 is classified as 'Conflicting_classifications_of_pathogenicity' for Familial_cancer_of_breast|Breast-ovarian_cancer,_familial,_susceptibility_to,_1|Hereditary_nonpolyposis_colon_cancer|Hereditary_cancer-predisposing_syndrome|not_provided|not_specified. Molecular consequence: SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480,Orphanet:227535|MONDO:MONDO:0011450,MedGen:C2676676,OMIM:604370,Orphanet:145|MONDO:MONDO:0018630,MedGen:C1333990,OMIM:PS120435,Orphanet:443909|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MedGen:C3661900|MedGen:CN169374. Review status: criteria provided, conflicting classifications.