A: The variant NC_000019.10:g.49819240A>C in gene MED25 is classified as 'Uncertain_significance' for Inborn_genetic_diseases|Charcot-Marie-Tooth_disease|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0015626,MedGen:C0007959,OMIM:PS118220,Orphanet:166|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.