A: The variant NC_000022.11:g.41524897G>A in gene ACO2 is classified as 'Conflicting_classifications_of_pathogenicity' for Mitochondrial_disease|Optic_atrophy_9. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0044970,MeSH:D028361,MedGen:C0751651,Orphanet:68380|MONDO:MONDO:0014571,MedGen:C4225384,OMIM:616289. Review status: criteria provided, conflicting classifications.