A: The variant NC_000021.9:g.36219469_36219470del in gene DOP1B is classified as 'Uncertain_significance' for Keratoconus. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: Human_Phenotype_Ontology:HP:0000563,MONDO:MONDO:0015486,MeSH:D007640,MedGen:C0022578,OMIM:PS148300. Review status: no assertion criteria provided.