A: The variant NC_000019.10:g.49830872C>T in gene MED25 is classified as 'Likely_benign' for Polyneuropathy|Charcot-Marie-Tooth_disease_type_2. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0001271,Human_Phenotype_Ontology:HP:0006941,Human_Phenotype_Ontology:HP:0007287,MONDO:MONDO:0001824,MedGen:C0152025|MONDO:MONDO:0018993,MedGen:C0270914,Orphanet:64746. Review status: criteria provided, single submitter.