A: The variant NC_000021.9:g.25891856C>T in gene APP is classified as 'Pathogenic' for ABeta_amyloidosis,_Italian_type|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0017947,MedGen:C3888308,Orphanet:324713|MedGen:CN517202. Review status: no assertion criteria provided.