A: The variant NC_000021.9:g.34859520G>C in gene RUNX1 is classified as 'Pathogenic' for Hereditary_thrombocytopenia_and_hematologic_cancer_predisposition_syndrome|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011071,MedGen:CN281654,Orphanet:71290|MedGen:C3661900. Review status: reviewed by expert panel.