A: The variant NC_000022.11:g.50625446_50625454del in gene ARSA is classified as 'Pathogenic/Likely_pathogenic' for Metachromatic_leukodystrophy|not_provided. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MONDO:MONDO:0018868,MedGen:C0023522,OMIM:250100,Orphanet:512|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.