A: The variant NC_000019.10:g.43744862A>T in gene SMG9 is classified as 'Uncertain_significance' for not_provided|Heart_and_brain_malformation_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0014833,MedGen:C4310793,OMIM:616920. Review status: criteria provided, multiple submitters, no conflicts.