A: The variant NC_000022.11:g.36480767C>T in gene TXN2 is classified as 'Pathogenic' for Combined_oxidative_phosphorylation_deficiency_29. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014781,MedGen:C5567607,OMIM:616811,Orphanet:478029. Review status: no assertion criteria provided.