A: The variant NC_000022.11:g.18126936C>T in gene TUBA8 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Polymicrogyria_with_optic_nerve_hypoplasia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0013172,MedGen:C2750798,Orphanet:250972. Review status: criteria provided, conflicting classifications.