A: The variant NC_000022.11:g.20056005T>G in gene TANGO2 is classified as 'Uncertain_significance' for Recurrent_metabolic_encephalomyopathic_crises-rhabdomyolysis-cardiac_arrhythmia-intellectual_disability_syndrome. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0018820,MedGen:C5567524,OMIM:616878,Orphanet:480864. Review status: criteria provided, multiple submitters, no conflicts.