A: The variant NC_000020.11:g.35437879A>G in gene GDF5 is classified as 'Uncertain_significance' for Grebe_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0008703,MedGen:C0265260,OMIM:200700,Orphanet:2098. Review status: criteria provided, single submitter.