A: The variant NC_000019.10:g.38505061G>A in gene RYR1 is classified as 'Uncertain_significance' for not_specified|not_provided|Malignant_hyperthermia_of_anesthesia|Malignant_hyperthermia,_susceptibility_to,_1|RYR1-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MedGen:C3661900|Human_Phenotype_Ontology:HP:0034733,MONDO:MONDO:0018493,MedGen:C0024591,Orphanet:423|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|MedGen:CN239331. Review status: reviewed by expert panel.