A: The variant NC_000020.11:g.19992203dup in gene RIN2 is classified as 'Likely_pathogenic' for RIN2_syndrome. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0013115,MedGen:C2751321,OMIM:613075,Orphanet:217335. Review status: criteria provided, single submitter.