A: The variant NC_000019.10:g.40396447T>G in gene PRX is classified as 'Likely_pathogenic' for Tip-toe_gait. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0002394,Human_Phenotype_Ontology:HP:0030051,Human_Phenotype_Ontology:HP:0040083,MedGen:C0427144. Review status: criteria provided, single submitter.