A: The variant NC_000019.10:g.50791734G>C in gene ACP4 is classified as 'Pathogenic' for Amelogenesis_imperfecta,_type_1J. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0015008,MedGen:C4310630,OMIM:617297. Review status: no assertion criteria provided.