A: The variant NC_000019.10:g.18868625A>G in gene GDF1 is classified as 'Pathogenic/Likely_pathogenic' for Heart,_malformation_of|not_provided|Congenital_heart_defects,_multiple_types,_6|Right_atrial_isomerism. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009327,MeSH:D006330,MedGen:C0018798,OMIM:140500,OMIM:234750|MedGen:C3661900|MONDO:MONDO:0013463,MedGen:C3151221,OMIM:613854,Orphanet:860|Human_Phenotype_Ontology:HP:0011536,MONDO:MONDO:0008832,MedGen:C3178806,OMIM:208530,Orphanet:97548. Review status: criteria provided, multiple submitters, no conflicts.