A: The variant NC_000019.10:g.49863967G>A in gene PNKP is classified as 'Conflicting_classifications_of_pathogenicity' for not_specified|Developmental_and_epileptic_encephalopathy,_12. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0013389,MedGen:C3150988,OMIM:613722. Review status: criteria provided, conflicting classifications.