A: The variant NC_000019.10:g.49835899del in gene MED25 is classified as 'Conflicting_classifications_of_pathogenicity' for Congenital_cataract-microcephaly-nevus_flammeus_simplex-severe_intellectual_disability_syndrome|Charcot-Marie-Tooth_disease_type_2. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0014643,MedGen:C4225323,OMIM:616449,Orphanet:464738|MONDO:MONDO:0018993,MedGen:C0270914,Orphanet:64746. Review status: criteria provided, conflicting classifications.