A: The variant NC_000019.10:g.45352316G>A in gene ERCC2 is classified as 'Uncertain_significance' for not_specified|Xeroderma_pigmentosum,_group_D|Inborn_genetic_diseases|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0010212,MedGen:C0268138,OMIM:278730|MeSH:D030342,MedGen:C0950123|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.