A: The variant NC_000022.11:g.39659827T>A in gene CACNA1I is classified as 'Pathogenic' for Neurodevelopmental_disorder_with_speech_impairment_and_with_or_without_seizures. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0859313,MedGen:C5774252,OMIM:620114. Review status: no assertion criteria provided.