A: The variant NC_000019.10:g.15197551C>A in gene NOTCH3 is classified as 'Pathogenic' for not_provided|Prostate_cancer. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|Human_Phenotype_Ontology:HP:0012125,MONDO:MONDO:0008315,MedGen:C0376358,Orphanet:1331. Review status: criteria provided, single submitter.