A: The variant NC_000019.10:g.49811409G>A in gene FUZ is classified as 'Uncertain_significance|association' for not_specified|Neural_tube_defect. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|Human_Phenotype_Ontology:HP:0045005,MONDO:MONDO:0018075,MedGen:C0027794,Orphanet:3388,Orphanet:823. Review status: criteria provided, multiple submitters, no conflicts.