A: The variant NC_000020.11:g.23637790C>T in gene CST3 is classified as 'Benign' for Hereditary_cerebral_amyloid_angiopathy,_Icelandic_type|Age_related_macular_degeneration_11|not_provided|not_specified. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007098,MedGen:C1527338,OMIM:105150,Orphanet:100008,Orphanet:85458|MONDO:MONDO:0012767,MedGen:C2677774,OMIM:611953|MedGen:C3661900|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.