A: The variant NC_000020.11:g.33791457T>C in gene ZNF341 is classified as 'Benign' for ZNF341-related_disorder|Hyper-IgE_recurrent_infection_syndrome_3,_autosomal_recessive|not_specified|not_provided. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: .|MONDO:MONDO:0032654,MedGen:C4748969,OMIM:618282|MedGen:CN169374|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.