A: The variant NC_000019.10:g.15053883G>A in gene CASP14 is classified as 'Uncertain_significance' for Ichthyosis,_congenital,_autosomal_recessive_12. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0015018,MedGen:C4310621,OMIM:617320. Review status: criteria provided, single submitter.