A: The variant NC_000019.10:g.49864042G>A in gene PNKP is classified as 'Conflicting_classifications_of_pathogenicity' for Microcephaly,_seizures,_and_developmental_delay|Developmental_and_epileptic_encephalopathy,_12|not_specified|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013254,MedGen:C3150667,OMIM:613402,Orphanet:1934|MONDO:MONDO:0013389,MedGen:C3150988,OMIM:613722|MedGen:CN169374|MedGen:C3661900. Review status: criteria provided, conflicting classifications.