A: The variant NC_000021.9:g.37493086G>T in gene DYRK1A is classified as 'Likely_pathogenic' for Male_infertility_with_spermatogenesis_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C5681167,Orphanet:399775. Review status: criteria provided, single submitter.