A: The variant NC_000020.11:g.59324624A>G in gene EDN3 is classified as 'Benign/Likely_benign' for Hirschsprung_disease,_susceptibility_to,_4|not_provided. Molecular consequence: SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013384,MedGen:C3150975,OMIM:613712,Orphanet:388|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.