A: The variant NC_000022.11:g.39513649T>A in gene MIEF1 is classified as 'Pathogenic' for Optic_atrophy_14. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957824,MedGen:C5882708,OMIM:620550. Review status: no assertion criteria provided.