A: The variant NC_000021.9:g.45505194G>A in gene SLC19A1 is classified as 'Uncertain_significance' for not_provided|Knobloch_syndrome_1|Hereditary_glaucoma,_primary_closed-angle. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0800167,MedGen:C4551775,OMIM:267750|MONDO:MONDO:0030038,MedGen:C5394374,OMIM:618880. Review status: criteria provided, multiple submitters, no conflicts.