A: The variant NC_000020.11:g.49374519G>T in gene KCNB1 is classified as 'Pathogenic/Likely_pathogenic' for Neurodevelopmental_delay|Inborn_genetic_diseases|Developmental_and_epileptic_encephalopathy,_26|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0012758,MedGen:C4022738|MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0014477,MedGen:C4015119,OMIM:616056,Orphanet:442835|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.