A: The variant NC_000020.11:g.35434423del in gene GDF5 is classified as 'Pathogenic' for not_provided|Brachydactyly_type_C. Molecular consequence: SO:0001589: frameshift_variant,SO:0001619: non-coding_transcript_variant. Variant type: Deletion. Disease database links: MedGen:C3661900|Human_Phenotype_Ontology:HP:0009373,MONDO:MONDO:0007221,MedGen:C1862103,OMIM:113100,Orphanet:93384. Review status: criteria provided, multiple submitters, no conflicts.