A: The variant NC_000019.10:g.15192394C>T in gene NOTCH3 is classified as 'Pathogenic' for Vascular_dementia|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0004648,MeSH:D015140,MedGen:C0011269|MedGen:C3661900. Review status: criteria provided, single submitter.