A: The variant NC_000019.10:g.19197184A>C in gene RFXANK is classified as 'Likely_pathogenic' for MHC_class_II_deficiency_2. Molecular consequence: SO:0001574: splice_acceptor_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0971013,MedGen:C1859535,OMIM:620815. Review status: criteria provided, single submitter.