A: The variant NC_000020.11:g.58853770C>T in gene GNAS is classified as 'Uncertain_significance' for GNAS-related_disorder|Pseudohypoparathyroidism_type_1C|Pseudohypoparathyroidism_type_1B|Pseudopseudohypoparathyroidism|Pseudohypoparathyroidism_type_I_A|McCune-Albright_syndrome. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: .|MONDO:MONDO:0012911,MedGen:C2932716,OMIM:612462,Orphanet:79444|MONDO:MONDO:0011301,MedGen:C1864100,OMIM:603233,Orphanet:94089|MONDO:MONDO:0012912,MedGen:C0033835,OMIM:612463,Orphanet:79445|MONDO:MONDO:0007078,MedGen:C3494506,OMIM:103580,Orphanet:79443|MONDO:MONDO:0018919,MedGen:C0242292,OMIM:174800,Orphanet:562. Review status: criteria provided, multiple submitters, no conflicts.