A: The variant NC_000020.11:g.18515656C>G in gene SEC23B is classified as 'Uncertain_significance' for Cowden_syndrome_7|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014802,MedGen:C4225179,OMIM:616858,Orphanet:201|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, multiple submitters, no conflicts.