A: The variant NC_000020.11:g.58909365C>A in gene GNAS is classified as 'Pathogenic' for PITUITARY_TUMOR_3,_GROWTH_HORMONE-SECRETING,_SOMATIC|Polyostotic_fibrous_dysplasia,_somatic,_mosaic|McCune-Albright_syndrome|ACTH-independent_macronodular_adrenal_hyperplasia_1. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:C2675383|MONDO:MONDO:0018919,MedGen:C0242292,OMIM:174800,Orphanet:562|MONDO:MONDO:0020735,MedGen:C1857451,OMIM:219080. Review status: no assertion criteria provided.