A: The variant NC_000019.10:g.47000632del in gene ARHGAP35 is classified as 'Pathogenic' for Irido-corneo-trabecular_dysgenesis. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: Human_Phenotype_Ontology:HP:0000659,MONDO:MONDO:0011414,MedGen:C0344559,OMIM:604229,Orphanet:708. Review status: criteria provided, single submitter.