A: The variant NC_000021.9:g.44533770_44533773del in gene TSPEAR is classified as 'Pathogenic' for Ectodermal_dysplasia_14,_hair/tooth_type,_with_hypohidrosis. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: .. Review status: no assertion criteria provided.