A: The variant NC_000019.10:g.49171675_49171677del in gene TRPM4 is classified as 'Conflicting_classifications_of_pathogenicity' for Progressive_familial_heart_block_type_IB|Cardiovascular_phenotype|not_specified|Progressive_familial_heart_block. Molecular consequence: SO:0001623: 5_prime_UTR_variant,SO:0001820: inframe_indel. Variant type: Deletion. Disease database links: MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871|MedGen:CN230736|MedGen:CN169374|MONDO:MONDO:0019490,MedGen:CN230454,OMIM:PS113900,Orphanet:871. Review status: criteria provided, conflicting classifications.