A: The variant NC_000020.11:g.64049274G>A in gene SOX18 is classified as 'Benign/Likely_benign' for not_provided|not_specified|Hypotrichosis-lymphedema-telangiectasia_syndrome|Hypotrichosis-lymphedema-telangiectasia-renal_defect_syndrome. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MedGen:CN169374|MONDO:MONDO:0011914,MedGen:C1843004,OMIM:607823,Orphanet:69735|MONDO:MONDO:0019073,MedGen:C4317151,OMIM:137940,Orphanet:69735. Review status: criteria provided, multiple submitters, no conflicts.