A: The variant NC_000021.9:g.25689909_25689912del in gene JAM2 is classified as 'Pathogenic' for Basal_ganglia_calcification,_idiopathic,_8,_autosomal_recessive. Molecular consequence: SO:0001589: frameshift_variant,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0032938,MedGen:C5394199,OMIM:618824. Review status: no assertion criteria provided.