A: The variant NC_000020.11:g.58440895G>T in gene VAPB is classified as 'Likely_benign' for Amyotrophic_lateral_sclerosis_type_8|Adult-onset_proximal_spinal_muscular_atrophy,_autosomal_dominant. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0012077,MedGen:C1837728,OMIM:608627,Orphanet:803|MONDO:MONDO:0008453,MedGen:C1854058,OMIM:182980,Orphanet:209335. Review status: criteria provided, single submitter.