A: The variant NC_000022.11:g.41527919_41527920del in gene ACO2 is classified as 'Pathogenic' for Inborn_genetic_diseases|not_provided. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Deletion. Disease database links: MeSH:D030342,MedGen:C0950123|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.