A: The variant NC_000019.10:g.38532542G>A in gene RYR1 is classified as 'Conflicting_classifications_of_pathogenicity' for Malignant_hyperthermia,_susceptibility_to,_1|Central_core_myopathy. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597. Review status: criteria provided, conflicting classifications.