A: The variant NC_000022.11:g.18126490T>G in gene TUBA8 is classified as 'Uncertain_significance' for Duane_retraction_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0001109,Human_Phenotype_Ontology:HP:0009921,MONDO:MONDO:0007473,MedGen:C0013261,OMIM:PS126800,Orphanet:233. Review status: criteria provided, single submitter.