A: The variant NC_000021.9:g.33823485A>G in gene ITSN1 is classified as 'Likely_pathogenic' for Generalized-onset_seizure. Molecular consequence: SO:0001574: splice_acceptor_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0002197,Human_Phenotype_Ontology:HP:0002409,Human_Phenotype_Ontology:HP:0007114,Human_Phenotype_Ontology:HP:0007339,MedGen:C0234533. Review status: criteria provided, single submitter.