A: The variant NC_000019.10:g.58549855C>T in gene TRIM28 is classified as 'Pathogenic' for Nephroblastoma. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000115,Human_Phenotype_Ontology:HP:0002667,MONDO:MONDO:0006058,MeSH:D009396,MedGen:C0027708,Orphanet:654. Review status: criteria provided, single submitter.