A: The variant NC_000023.11:g.13756602del in gene OFD1 is classified as 'Pathogenic' for Orofaciodigital_syndrome_I|Orofacial-digital_syndrome_III. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0010702,MedGen:C1510460,OMIM:311200,Orphanet:2750|MONDO:MONDO:0009793,MedGen:C0406726,OMIM:258850,Orphanet:2752. Review status: criteria provided, single submitter.