A: The variant NC_000022.11:g.20727781G>T in gene PI4KA is classified as 'Uncertain_significance' for Tuberous_sclerosis_1. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0008612,MedGen:C1854465,OMIM:191100,Orphanet:805. Review status: criteria provided, single submitter.