A: The variant NC_000020.11:g.13072400T>C in gene SPTLC3 is classified as 'Likely_pathogenic' for Peripheral_neuropathy|Sensory_neuropathy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0003157,Human_Phenotype_Ontology:HP:0003407,Human_Phenotype_Ontology:HP:0007088,Human_Phenotype_Ontology:HP:0007235,Human_Phenotype_Ontology:HP:0007355,Human_Phenotype_Ontology:HP:0009830,MONDO:MONDO:0005244,MedGen:C0031117|Human_Phenotype_Ontology:HP:0000763,Human_Phenotype_Ontology:HP:0003410,Human_Phenotype_Ontology:HP:0006815,Human_Phenotype_Ontology:HP:0007043,Human_Phenotype_Ontology:HP:0007142,MONDO:MONDO:0002321,MedGen:C0151313. Review status: criteria provided, single submitter.