A: The variant NC_000019.10:g.38473488C>A in gene RYR1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Congenital_myopathy_with_fiber_type_disproportion|Malignant_hyperthermia,_susceptibility_to,_1|Multiminicore_myopathy|Centronuclear_myopathy|RYR1-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0009711,MedGen:C0546264,Orphanet:2020|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|MONDO:MONDO:0018948,MedGen:C0270962,Orphanet:598|MONDO:MONDO:0018947,MedGen:C0175709,OMIM:PS160150,Orphanet:595|MedGen:CN239331. Review status: criteria provided, conflicting classifications.