A: The variant NC_000022.11:g.50523636G>A in gene TYMP is classified as 'Benign/Likely_benign' for not_provided|Fatal_Infantile_Cardioencephalomyopathy|Mitochondrial_complex_IV_deficiency,_nuclear_type_1|Mitochondrial_DNA_depletion_syndrome_1|Cardioencephalomyopathy,_fatal_infantile,_due_to_cytochrome_c_oxidase_deficiency_1. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MedGen:CN239235|MONDO:MONDO:0700250,MedGen:C5435656,OMIM:220110|MONDO:MONDO:0011283,MedGen:C4551995,OMIM:603041,Orphanet:298|MONDO:MONDO:0011451,MedGen:C5399977,OMIM:604377,Orphanet:1561. Review status: criteria provided, multiple submitters, no conflicts.