A: The variant NC_000019.10:g.39498963dup in gene DLL3 is classified as 'Uncertain_significance' for Spondylocostal_dysostosis|Syndactyly. Molecular consequence: SO:0001623: 5_prime_UTR_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0000359,MedGen:C0265343,OMIM:PS277300|Human_Phenotype_Ontology:HP:0001159,Human_Phenotype_Ontology:HP:0001206,Human_Phenotype_Ontology:HP:0001236,MONDO:MONDO:0021002,MedGen:C0039075. Review status: criteria provided, single submitter.