A: The variant NC_000019.10:g.49167950G>A in gene TRPM4 is classified as 'Benign/Likely_benign' for Progressive_familial_heart_block_type_IB|not_specified|Cardiovascular_phenotype|TRPM4-related_disorder|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871|MedGen:CN169374|MedGen:CN230736|MedGen:CN239424|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.