A: The variant NC_000019.10:g.46846118G>A in gene AP2S1 is classified as 'Conflicting_classifications_of_pathogenicity' for Familial_hypocalciuric_hypercalcemia_3|not_provided|Neurodevelopmental_disorder|AP2S1-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010926,MedGen:C1833372,OMIM:600740,Orphanet:101050,Orphanet:405|MedGen:C3661900|MONDO:MONDO:0700092,MeSH:D065886,MedGen:C1535926|.. Review status: criteria provided, conflicting classifications.