A: The variant NC_000020.11:g.58434702dup in gene VAPB is classified as 'Uncertain_significance' for not_provided|VAPB-related_disorder. Molecular consequence: SO:0001589: frameshift_variant,SO:0001627: intron_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|.. Review status: criteria provided, single submitter.