A: The variant NC_000019.10:g.42354641T>C in gene MEGF8 is classified as 'Benign' for MEGF8-related_Carpenter_syndrome|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013998,MedGen:C3554247,OMIM:614976,Orphanet:65759|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.