A: The variant NC_000019.10:g.18786051C>A in gene COMP is classified as 'Pathogenic' for Abnormality_of_the_skeletal_system. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000924,MedGen:C4021790. Review status: criteria provided, single submitter.