A: The variant NC_000019.10:g.16088078C>T in gene TPM4 is classified as 'Pathogenic' for Bleeding_disorder,_platelet-type,_25. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957580,MedGen:C5882683,OMIM:620486. Review status: no assertion criteria provided.