A: The variant NC_000022.11:g.37232842C>T in gene RAC2 is classified as 'Pathogenic/Likely_pathogenic' for Immunodeficiency_73b_with_defective_neutrophil_chemotaxis_and_lymphopenia|not_provided|Neutrophil_immunodeficiency_syndrome|Immunodeficiency_73c_with_defective_neutrophil_chemotaxis_and_hypogammaglobulinemia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0033554,MedGen:C5436549,OMIM:618986|MedGen:C3661900|MONDO:MONDO:0011988,MedGen:C1842398,OMIM:608203,Orphanet:183707|MONDO:MONDO:0033555,MedGen:C5436550,OMIM:618987. Review status: criteria provided, multiple submitters, no conflicts.