A: The variant NC_000019.10:g.17837148G>A in gene JAK3 is classified as 'Conflicting_classifications_of_pathogenicity' for T-B+_severe_combined_immunodeficiency_due_to_JAK3_deficiency|not_provided|Severe_combined_immunodeficiency_disease. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010938,MedGen:C1833275,OMIM:600802,Orphanet:35078|MedGen:C3661900|Human_Phenotype_Ontology:HP:0004430,MONDO:MONDO:0015974,MeSH:D016511,MedGen:C0085110,Orphanet:183660. Review status: criteria provided, conflicting classifications.