A: The variant NC_000022.11:g.20729329C>T in gene PI4KA is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|not_specified|Spastic_paraplegia_84,_autosomal_recessive. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MedGen:CN169374|MONDO:MONDO:0030482,MedGen:C5562025,OMIM:619621,Orphanet:631079. Review status: criteria provided, conflicting classifications.