A: The variant NC_000020.11:g.22582623G>A in gene FOXA2 is classified as 'Likely_pathogenic' for Non-acquired_combined_pituitary_hormone_deficiency. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0018762,MedGen:C5680091,Orphanet:467. Review status: criteria provided, single submitter.