A: The variant NC_000023.11:g.15331406A>G in gene PIGA is classified as 'Benign/Likely_benign' for not_specified|Multiple_congenital_anomalies-hypotonia-seizures_syndrome_2|Paroxysmal_nocturnal_hemoglobinuria_1|Neurodevelopmental_disorder_with_epilepsy_and_hemochromatosis|Inborn_genetic_diseases. Molecular consequence: SO:0001627: intron_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0010466,MedGen:C3275508,OMIM:300868,Orphanet:300496|MONDO:MONDO:0010438,MedGen:C3806670,OMIM:300818,Orphanet:447|MedGen:CN307964,OMIM:301072|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, multiple submitters, no conflicts.