A: The variant NC_000019.10:g.45419157G>A in gene ERCC1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Premature_ovarian_insufficiency|Global_proximal_tubulopathy|Cutaneous_photosensitivity|Cholestatic_liver_disease|Failure_to_thrive. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|Human_Phenotype_Ontology:HP:0001587,Human_Phenotype_Ontology:HP:0008209,Human_Phenotype_Ontology:HP:0100805,MONDO:MONDO:0001119,MedGen:C0025322|Human_Phenotype_Ontology:HP:0012573,MedGen:C4022839|Human_Phenotype_Ontology:HP:0000992,Human_Phenotype_Ontology:HP:0005594,Human_Phenotype_Ontology:HP:0006831,Human_Phenotype_Ontology:HP:0007538,MONDO:MONDO:0005434,MedGen:C0349506|Human_Phenotype_Ontology:HP:0002611,MedGen:C0860204|Human_Phenotype_Ontology:HP:0001508,Human_Phenotype_Ontology:HP:0001535,Human_Phenotype_Ontology:HP:0008853,Human_Phenotype_Ontology:HP:0008878,Human_Phenotype_Ontology:HP:0008916,MedGen:C2315100. Review status: criteria provided, conflicting classifications.