A: The variant NC_000020.11:g.23635255del in gene CST3 is classified as 'Uncertain_significance' for CST3-related_Leukodystrophy|not_provided. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: Deletion. Disease database links: .|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.