A: The variant NC_000022.11:g.30615399C>T in gene TCN2 is classified as 'Pathogenic/Likely_pathogenic' for Transcobalamin_II_deficiency|TCN2-related_disorder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010149,MedGen:C0342701,OMIM:275350,Orphanet:859|.. Review status: criteria provided, multiple submitters, no conflicts.