A: The variant NC_000021.9:g.43774730G>A in gene CSTB is classified as 'Likely_benign' for Progressive_myoclonic_epilepsy|Inborn_genetic_diseases. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0020074,MedGen:C0751778,OMIM:PS254800,Orphanet:308,Orphanet:98261|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, multiple submitters, no conflicts.