A: The variant NC_000022.11:g.20994184C>T in gene LZTR1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_specified|Hereditary_cancer-predisposing_syndrome|Cardiovascular_phenotype|not_provided|Noonan_syndrome_and_Noonan-related_syndrome|LZTR1-related_disorder. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MedGen:CN230736|MedGen:C3661900|MONDO:MONDO:0020297,MedGen:C5681679,Orphanet:98733|.. Review status: criteria provided, conflicting classifications.