A: The variant NC_000022.11:g.41166607G>C in gene EP300 is classified as 'Conflicting_classifications_of_pathogenicity' for Menke-Hennekam_syndrome_2|Rubinstein-Taybi_syndrome_due_to_EP300_haploinsufficiency|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0020769,MedGen:C5193035,OMIM:618333|MONDO:MONDO:0013364,MedGen:C3150941,OMIM:613684,Orphanet:353284,Orphanet:783|MedGen:C3661900. Review status: criteria provided, conflicting classifications.