A: The variant NC_000021.9:g.42380123C>T in gene TMPRSS3 is classified as 'Conflicting_classifications_of_pathogenicity' for not_specified|Autosomal_recessive_nonsyndromic_hearing_loss_8|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0010987,MedGen:C1832827,OMIM:601072,Orphanet:90636|MedGen:C3661900. Review status: criteria provided, conflicting classifications.