A: The variant NC_000019.10:g.38500898C>T in gene RYR1 is classified as 'Likely_pathogenic' for not_provided|Congenital_myopathy_with_fiber_type_disproportion|Central_core_myopathy|Malignant_hyperthermia,_susceptibility_to,_1|RYR1-related_disorder|Abnormality_of_the_musculature|Inborn_genetic_diseases|King_Denborough_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0009711,MedGen:C0546264,Orphanet:2020|MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|MedGen:CN239331|Human_Phenotype_Ontology:HP:0003011,Human_Phenotype_Ontology:HP:0003197,Human_Phenotype_Ontology:HP:0003708,MedGen:C4021745|MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0020485,MedGen:C1840365,OMIM:619542. Review status: reviewed by expert panel.