A: The variant NC_000019.10:g.49663393C>T in gene IRF3 is classified as 'Benign' for IRF3-related_disorder|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.