A: The variant NC_000019.10:g.35651261G>C in gene COX6B1 is classified as 'Uncertain_significance' for Mitochondrial_complex_4_deficiency,_nuclear_type_7|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0033637,MedGen:C5436685,OMIM:619051|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.