A: The variant NC_000019.10:g.50406171CTC[2] in gene POLD1 is classified as 'Conflicting_classifications_of_pathogenicity' for Polymerase_proofreading-related_adenomatous_polyposis|Colorectal_cancer,_susceptibility_to,_10|not_provided|Immunodeficiency_120|Mandibular_hypoplasia-deafness-progeroid_syndrome|POLD1-related_disorder|Malignant_tumor_of_breast. Molecular consequence: SO:0001627: intron_variant. Variant type: Microsatellite. Disease database links: MONDO:MONDO:0018653,MedGen:C0130294,Orphanet:447877|MONDO:MONDO:0012953,MedGen:C2675481,OMIM:612591,Orphanet:220460|MedGen:C3661900|MONDO:MONDO:0970994,MedGen:C5935622,OMIM:620836|MONDO:MONDO:0014157,MedGen:C3715192,OMIM:615381,Orphanet:363649|.|MONDO:MONDO:0007254,MedGen:C0006142. Review status: criteria provided, conflicting classifications.