A: The variant NC_000022.11:g.19524092A>G in gene CLDN5 is classified as 'Uncertain_significance' for Neurodevelopmental_abnormality. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0012759,MedGen:C4022737. Review status: no assertion criteria provided.