A: The variant NC_000021.9:g.45477788G>A in gene COL18A1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Knobloch_syndrome. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0800166,MedGen:C1849409,OMIM:PS267750,Orphanet:1571. Review status: criteria provided, conflicting classifications.