A: The variant NC_000020.11:g.58678654_58678657dup in gene STX16 is classified as 'Uncertain_significance' for Autosomal_dominant_pseudohypoaldosteronism_type_1. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0008329,MedGen:C1449842,OMIM:177735,Orphanet:171871,Orphanet:756. Review status: criteria provided, single submitter.