A: The variant NC_000020.11:g.41172577C>T in gene PLCG1 is classified as 'Pathogenic' for Immune_dysregulation,_autoimmunity,_and_autoinflammation. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957790,MedGen:C5848750,OMIM:620514. Review status: no assertion criteria provided.