A: The variant NC_000022.11:g.20991724C>T in gene LZTR1 is classified as 'Uncertain_significance' for Noonan_syndrome_and_Noonan-related_syndrome. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0020297,MedGen:C5681679,Orphanet:98733. Review status: criteria provided, single submitter.