A: The variant NC_000020.11:g.63350969G>A in gene CHRNA4 is classified as 'Conflicting_classifications_of_pathogenicity' for Amyotrophic_lateral_sclerosis|Inborn_genetic_diseases|Autosomal_dominant_nocturnal_frontal_lobe_epilepsy|Tobacco_use_disorder|not_specified|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0007354,MONDO:MONDO:0004976,MedGen:C0002736,Orphanet:803|MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0020300,MedGen:C3696898,Orphanet:98784|MedGen:C0040336|MedGen:CN169374|MedGen:C3661900. Review status: criteria provided, conflicting classifications.