A: The variant NC_000019.10:g.49183159C>T in gene TRPM4 is classified as 'Uncertain_significance' for Cardiovascular_phenotype|Brugada_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN230736|MONDO:MONDO:0015263,MedGen:C1142166,OMIM:PS601144,Orphanet:130. Review status: criteria provided, multiple submitters, no conflicts.