A: The variant NC_000022.11:g.20995799T>G in gene LZTR1 is classified as 'Uncertain_significance' for Noonan_syndrome|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0018997,MeSH:D009634,MedGen:C0028326,OMIM:PS163950,Orphanet:648|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.