A: The variant NC_000019.10:g.19194086del in gene RFXANK is classified as 'Likely_pathogenic' for MHC_class_II_deficiency_2. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0971013,MedGen:C1859535,OMIM:620815. Review status: criteria provided, single submitter.