A: The variant NC_000019.10:g.16086478C>T in gene TPM4 is classified as 'Pathogenic' for not_provided|Bleeding_disorder,_platelet-type,_25. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0957580,MedGen:C5882683,OMIM:620486. Review status: criteria provided, single submitter.