A: The variant NC_000022.11:g.29137450_29137466dup in gene KREMEN1 is classified as 'Uncertain_significance' for Ectodermal_dysplasia_13,_hair/tooth_type. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0044305,MedGen:C4479322,OMIM:617392. Review status: criteria provided, single submitter.