A: The variant NC_000022.11:g.46398553C>T in gene CELSR1 is classified as 'Uncertain_significance' for Heterotaxy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0030853,MedGen:C0266642,Orphanet:157769. Review status: no assertion criteria provided.