A: The variant NC_000020.11:g.8790220C>T in gene PLCB1 is classified as 'Pathogenic' for Self-limited_epilepsy_with_centrotemporal_spikes. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007295,MedGen:C0376532,Orphanet:1945. Review status: no assertion criteria provided.