A: The variant NC_000021.9:g.43072192A>G in gene CBS is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|HYPERHOMOCYSTEINEMIA,_THROMBOTIC,_CBS-RELATED. Molecular consequence: SO:0001582: initiator_codon_variant,SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MedGen:C3150344. Review status: criteria provided, conflicting classifications.