A: The variant NC_000022.11:g.46439346T>C in gene CELSR1 is classified as 'Uncertain_significance' for CELSR1-related_disorder|not_specified. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:CN169374. Review status: criteria provided, single submitter.