A: The variant NC_000020.11:g.33748903C>G in gene ZNF341 is classified as 'Benign/Likely_benign' for Hyper-IgE_recurrent_infection_syndrome_3,_autosomal_recessive|not_provided. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0032654,MedGen:C4748969,OMIM:618282|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.