A: The variant NC_000022.11:g.35416388C>T in gene MCM5 is classified as 'Pathogenic' for Meier-Gorlin_syndrome_8. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0033046,MedGen:C4479655,OMIM:617564. Review status: no assertion criteria provided.