A: The variant NC_000019.10:g.19193954_19193957del in gene RFXANK is classified as 'Likely_pathogenic' for MHC_class_II_deficiency_1. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0971005,MedGen:CN377826,OMIM:209920. Review status: criteria provided, single submitter.