A: The variant NC_000022.11:g.50525826C>T in gene TYMP is classified as 'Benign/Likely_benign' for Mitochondrial_neurogastrointestinal_encephalomyopathy|Fatal_Infantile_Cardioencephalomyopathy|not_specified|TYMP-related_disorder|not_provided|Mitochondrial_DNA_depletion_syndrome_1. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0017575,MedGen:C0872218,Orphanet:298|MedGen:CN239235|MedGen:CN169374|.|MedGen:C3661900|MONDO:MONDO:0011283,MedGen:C4551995,OMIM:603041,Orphanet:298. Review status: criteria provided, multiple submitters, no conflicts.