A: The variant NC_000023.11:g.10449607T>C in gene MID1 is classified as 'Uncertain_significance' for Corpus_callosum,_agenesis_of|Low-set_ears|Hypertelorism|Abnormal_facial_shape|Clinodactyly_of_the_5th_finger. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0001274,Human_Phenotype_Ontology:HP:0006800,MONDO:MONDO:0009022,MedGen:C0175754,OMIM:217990,Orphanet:200|Human_Phenotype_Ontology:HP:0000369,MedGen:C0239234|Human_Phenotype_Ontology:HP:0000316,Human_Phenotype_Ontology:HP:0000578,Human_Phenotype_Ontology:HP:0002001,Human_Phenotype_Ontology:HP:0004657,Human_Phenotype_Ontology:HP:0007871,MedGen:C0020534,OMIM:145400|Human_Phenotype_Ontology:HP:0001999,Human_Phenotype_Ontology:HP:0002004,Human_Phenotype_Ontology:HP:0002260,Human_Phenotype_Ontology:HP:0004643,Human_Phenotype_Ontology:HP:0004649,Human_Phenotype_Ontology:HP:0004652,Human_Phenotype_Ontology:HP:0004655,Human_Phenotype_Ontology:HP:0004675,Human_Phenotype_Ontology:HP:0005124,MedGen:C0424503|Human_Phenotype_Ontology:HP:0001158,Human_Phenotype_Ontology:HP:0001588,Human_Phenotype_Ontology:HP:0004209,Human_Phenotype_Ontology:HP:0004212,Human_Phenotype_Ontology:HP:0006083,Human_Phenotype_Ontology:HP:0006181,Human_Phenotype_Ontology:HP:0009181,MedGen:C1850049. Review status: criteria provided, single submitter.