A: The variant NC_000020.11:g.35437529del in gene GDF5 is classified as 'Pathogenic' for Grebe_syndrome. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0008703,MedGen:C0265260,OMIM:200700,Orphanet:2098. Review status: no assertion criteria provided.