A: The variant NC_000022.11:g.37139219G>A in gene IL2RB is classified as 'Pathogenic' for Ichthyosis. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000955,Human_Phenotype_Ontology:HP:0007547,Human_Phenotype_Ontology:HP:0008064,MONDO:MONDO:0019269,MedGen:C0020757,Orphanet:79354. Review status: no assertion criteria provided.