A: The variant NC_000019.10:g.42250332G>A in gene ERF is classified as 'Pathogenic' for not_provided|ERF-related_disorder|TWIST1-related_craniosynostosis|Craniosynostosis_4. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|.|MONDO:MONDO:0007399,MedGen:C4551902,OMIM:123100,Orphanet:63440|Human_Phenotype_Ontology:HP:0004443,Human_Phenotype_Ontology:HP:0004486,MONDO:MONDO:0010929,MedGen:C1833340,OMIM:600775. Review status: criteria provided, multiple submitters, no conflicts.