A: The variant NC_000019.10:g.16490519T>C in gene CALR3 is classified as 'Conflicting_classifications_of_pathogenicity' for Hypertrophic_cardiomyopathy|Hypertrophic_cardiomyopathy_19|not_specified|not_provided|Arrhythmogenic_right_ventricular_cardiomyopathy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0001639,MONDO:MONDO:0005045,MeSH:D002312,MedGen:C0007194,Orphanet:217569|MONDO:MONDO:0013476,MedGen:CN077603|MedGen:CN169374|MedGen:C3661900|MONDO:MONDO:0016587,MeSH:D019571,MedGen:C0349788,Orphanet:247. Review status: criteria provided, conflicting classifications.