A: The variant NC_000022.11:g.20987490_20987501del in gene LZTR1 is classified as 'Benign' for Cardiovascular_phenotype|Hereditary_cancer-predisposing_syndrome|Noonan_syndrome_and_Noonan-related_syndrome|not_specified|not_provided. Molecular consequence: SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MedGen:CN230736|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MONDO:MONDO:0020297,MedGen:C5681679,Orphanet:98733|MedGen:CN169374|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.