A: The variant NC_000021.9:g.44522001del in gene TSPEAR is classified as 'Likely_pathogenic' for Ectodermal_dysplasia_14,_hair/tooth_type_with_or_without_hypohidrosis. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0032584,MedGen:C4748560,OMIM:618180. Review status: criteria provided, single submitter.