A: The variant NC_000022.11:g.38112212A>C in gene PLA2G6 is classified as 'Pathogenic/Likely_pathogenic' for Abnormality_of_the_nervous_system|Neurodegeneration_with_brain_iron_accumulation|Autosomal_recessive_Parkinson_disease_14|Infantile_neuroaxonal_dystrophy|Neurodegeneration_with_brain_iron_accumulation_2B|PLA2G6-related_disorder|PLA2G6-associated_neurodegeneration|Inborn_genetic_diseases|Autism|Seizure|not_provided|Iron_accumulation_in_brain. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000707,Human_Phenotype_Ontology:HP:0001333,Human_Phenotype_Ontology:HP:0006987,MONDO:MONDO:0002320,MedGen:C0497552|MONDO:MONDO:0018307,MedGen:C2931845,OMIM:PS234200,Orphanet:385|MONDO:MONDO:0013060,MedGen:C2751842,OMIM:612953,Orphanet:199351|MONDO:MONDO:0024457,MedGen:C0270724,OMIM:256600,Orphanet:35069|MONDO:MONDO:0012444,MedGen:C1857747,OMIM:610217,Orphanet:35069|.|MONDO:MONDO:0017998,MedGen:CN204472,Orphanet:329303|MeSH:D030342,MedGen:C0950123|Human_Phenotype_Ontology:HP:0000717,MONDO:MONDO:0005260,MeSH:D001321,MedGen:C0004352,OMIM:209850|Human_Phenotype_Ontology:HP:0001250,Human_Phenotype_Ontology:HP:0001275,Human_Phenotype_Ontology:HP:0001303,Human_Phenotype_Ontology:HP:0002125,Human_Phenotype_Ontology:HP:0002182,Human_Phenotype_Ontology:HP:0002279,Human_Phenotype_Ontology:HP:0002306,Human_Phenotype_Ontology:HP:0002348,Human_Phenotype_Ontology:HP:0002391,Human_Phenotype_Ontology:HP:0002417,Human_Phenotype_Ontology:HP:0002430,Human_Phenotype_Ontology:HP:0002431,Human_Phenotype_Ontology:HP:0002432,Human_Phenotype_Ontology:HP:0002434,Human_Phenotype_Ontology:HP:0002437,Human_Phenotype_Ontology:HP:0002466,Human_Phenotype_Ontology:HP:0002479,Human_Phenotype_Ontology:HP:0002794,Human_Phenotype_Ontology:HP:0006997,Human_Phenotype_Ontology:HP:0010520,MedGen:C0036572|MedGen:C3661900|Human_Phenotype_Ontology:HP:0012675,MedGen:C4021076. Review status: criteria provided, multiple submitters, no conflicts.