A: The variant NC_000020.11:g.32434604_32434650del in gene ASXL1 is classified as 'Pathogenic' for Atypical_chronic_myeloid_leukemia,_BCR-ABL1_negative. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0004653,MedGen:C1292772,Orphanet:98824. Review status: no assertion criteria provided.