A: The variant NC_000020.11:g.25081924G>A in gene VSX1 is classified as 'Conflicting_classifications_of_pathogenicity' for Keratoconus|not_specified|VSX1-related_disorder|not_provided|Polymorphous_corneal_dystrophy. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000563,MONDO:MONDO:0015486,MeSH:D007640,MedGen:C0022578,OMIM:PS148300|MedGen:CN169374|.|MedGen:C3661900|Human_Phenotype_Ontology:HP:0007915,MONDO:MONDO:0020364,MedGen:C0339284,OMIM:PS122000,Orphanet:98973. Review status: criteria provided, conflicting classifications.