A: The variant NC_000019.10:g.38206169G>T in gene SIPA1L3 is classified as 'Uncertain_significance' for Cataract_45. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014799,MedGen:C4225182,OMIM:616851,Orphanet:91492. Review status: criteria provided, single submitter.