A: The variant NC_000021.9:g.31667290A>C in gene SOD1 is classified as 'Conflicting_classifications_of_pathogenicity' for Amyotrophic_lateral_sclerosis_type_1|Amyotrophic_lateral_sclerosis_1,_autosomal_recessive|SOD1-related_disorder|Amyotrophic_lateral_sclerosis|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803|MedGen:C5686324|.|Human_Phenotype_Ontology:HP:0007354,MONDO:MONDO:0004976,MedGen:C0002736,Orphanet:803|MedGen:C3661900. Review status: criteria provided, conflicting classifications.