A: The variant NC_000021.9:g.46219578C>G in gene LSS is classified as 'Benign' for Alopecia-intellectual_disability_syndrome_4|Cataract_44|not_provided. Molecular consequence: SO:0001627: intron_variant,SO:0002153: genic_upstream_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030009,MedGen:C5394241,OMIM:618840|MONDO:MONDO:0014673,MedGen:C4225300,OMIM:616509,Orphanet:91492,Orphanet:98994|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.