A: The variant NC_000021.9:g.18275293_18275294insGATT in gene TMPRSS15 is classified as 'Pathogenic' for Enterokinase_deficiency. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Insertion. Disease database links: MONDO:MONDO:0009173,MedGen:C0268416,OMIM:226200,Orphanet:168601. Review status: no assertion criteria provided.