A: The variant NC_000021.9:g.45222053G>A in gene ADARB1 is classified as 'Benign' for Neurodevelopmental_disorder_with_hypotonia,_microcephaly,_and_seizures|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030025,MedGen:C5394312,OMIM:618862|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.