A: The variant NC_000023.11:g.8534412G>A in gene ANOS1 is classified as 'Pathogenic' for not_provided|Hypogonadotropic_hypogonadism_1_with_or_without_anosmia|Martsolf_syndrome_1. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0010635,MedGen:C1563719,OMIM:308700,Orphanet:478|MONDO:MONDO:8000008,MedGen:C5542298,OMIM:212720,Orphanet:1387. Review status: criteria provided, multiple submitters, no conflicts.