A: The variant NC_000022.11:g.20996910C>T in gene LZTR1 is classified as 'Conflicting_classifications_of_pathogenicity' for Noonan_syndrome_and_Noonan-related_syndrome|Noonan_syndrome_10. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0020297,MedGen:C5681679,Orphanet:98733|MONDO:MONDO:0014693,MedGen:C4225280,OMIM:616564,Orphanet:648. Review status: criteria provided, conflicting classifications.