A: The variant NC_000019.10:g.35651301C>T in gene COX6B1 is classified as 'Likely_pathogenic' for Mitochondrial_complex_IV_deficiency,_nuclear_type_1. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0700250,MedGen:C5435656,OMIM:220110. Review status: criteria provided, single submitter.