A: The variant NC_000020.11:g.45950360C>T in gene ZNF335 is classified as 'Conflicting_classifications_of_pathogenicity' for Aminoacylase_1_deficiency|Microcephalic_primordial_dwarfism_due_to_ZNF335_deficiency|Autism. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0012368,MedGen:C1835922,OMIM:609924,Orphanet:137754|MONDO:MONDO:0014043,MedGen:C3554499,OMIM:615095,Orphanet:329228|Human_Phenotype_Ontology:HP:0000717,MONDO:MONDO:0005260,MeSH:D001321,MedGen:C0004352,OMIM:209850. Review status: no assertion criteria provided.