A: The variant NC_000019.10:g.49395259T>C in gene KASH5 is classified as 'Uncertain_significance' for Spermatogenic_failure_88. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957821,MedGen:C5882706,OMIM:620547. Review status: criteria provided, single submitter.