A: The variant NC_000019.10:g.49818402G>A in gene MED25 is classified as 'Uncertain_significance' for Autism|Charcot-Marie-Tooth_disease_type_2. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000717,MONDO:MONDO:0005260,MeSH:D001321,MedGen:C0004352,OMIM:209850|MONDO:MONDO:0018993,MedGen:C0270914,Orphanet:64746. Review status: criteria provided, single submitter.