A: The variant NC_000020.11:g.35675170G>A in gene NFS1 is classified as 'Uncertain_significance' for not_provided|Combined_oxidative_phosphorylation_deficiency_52. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0030311,MedGen:C5543592,OMIM:619386. Review status: criteria provided, multiple submitters, no conflicts.