A: The variant NC_000022.11:g.20988116A>T in gene LZTR1 is classified as 'Uncertain_significance' for Noonan_syndrome_10. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014693,MedGen:C4225280,OMIM:616564,Orphanet:648. Review status: criteria provided, single submitter.