A: The variant NC_000019.10:g.15191839G>A in gene NOTCH3 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Cerebral_arteriopathy,_autosomal_dominant,_with_subcortical_infarcts_and_leukoencephalopathy,_type_1|Inborn_genetic_diseases. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0000914,MedGen:C4551768,OMIM:125310,Orphanet:136|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, conflicting classifications.