A: The variant NC_000019.10:g.50399074T>C in gene POLD1 is classified as 'Benign' for not_provided|Mandibular_hypoplasia-deafness-progeroid_syndrome|not_specified. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0014157,MedGen:C3715192,OMIM:615381,Orphanet:363649|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.