A: The variant NC_000020.11:g.36905452_36905455del in gene SAMHD1 is classified as 'Likely_pathogenic' for Aicardi_Goutieres_syndrome. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0018866,MedGen:C0393591,OMIM:PS225750,Orphanet:51. Review status: criteria provided, single submitter.