A: The variant NC_000019.10:g.45357268dup in gene ERCC2 is classified as 'Conflicting_classifications_of_pathogenicity' for Cerebrooculofacioskeletal_syndrome_2|Trichothiodystrophy_1,_photosensitive|Xeroderma_pigmentosum,_group_D|not_provided|ERCC2-related_disorder|Xeroderma_pigmentosum. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0012553,MedGen:C1853102,OMIM:610756|MONDO:MONDO:0011125,MedGen:C1866504,OMIM:601675,Orphanet:33364,Orphanet:670|MONDO:MONDO:0010212,MedGen:C0268138,OMIM:278730|MedGen:C3661900|MedGen:CN239291|MONDO:MONDO:0019600,MedGen:C0043346,Orphanet:910. Review status: criteria provided, conflicting classifications.