A: The variant NC_000019.10:g.49211240C>T in gene TRPM4 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Conduction_disorder_of_the_heart|Progressive_familial_heart_block_type_IB|not_specified|Family_history_of_sudden_cardiac_death|Cardiovascular_phenotype. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0100042,MedGen:C0264886,OMIM:115080,Orphanet:871|MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871|MedGen:CN169374|MedGen:C2825161|MedGen:CN230736. Review status: criteria provided, conflicting classifications.