A: The variant NC_000019.10:g.18869135_18869198dup in gene GDF1 is classified as 'Pathogenic' for Visceral_heterotaxy. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0018677,MedGen:C3178805,OMIM:PS306955,Orphanet:450. Review status: criteria provided, single submitter.