A: The variant NC_000022.11:g.41515521C>T in gene ACO2 is classified as 'Benign' for not_provided|Optic_atrophy_9|Infantile_cerebellar-retinal_degeneration|not_specified. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0014571,MedGen:C4225384,OMIM:616289|MONDO:MONDO:0013802,MedGen:C3281192,OMIM:614559,Orphanet:313850|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.