A: The variant NC_000021.9:g.43416924_43416926del in gene SIK1 is classified as 'Uncertain_significance' for Developmental_and_epileptic_encephalopathy,_30. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MONDO:MONDO:0014595,MedGen:C4225360,OMIM:616341. Review status: criteria provided, single submitter.