A: The variant NC_000019.10:g.38467666_38467671dup in gene RYR1 is classified as 'Conflicting_classifications_of_pathogenicity' for Malignant_hyperthermia,_susceptibility_to,_1|Myopathy. Molecular consequence: SO:0001821: inframe_insertion. Variant type: Duplication. Disease database links: MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|Human_Phenotype_Ontology:HP:0003198,Human_Phenotype_Ontology:HP:0003569,Human_Phenotype_Ontology:HP:0003705,Human_Phenotype_Ontology:HP:0003742,Human_Phenotype_Ontology:HP:0003802,MONDO:MONDO:0005336,MeSH:D009135,MedGen:C0026848. Review status: criteria provided, conflicting classifications.