A: The variant NC_000022.11:g.31857530A>C in gene DEPDC5 is classified as 'Likely_benign' for Self-limited_epilepsy_with_centrotemporal_spikes|Epilepsy,_familial_focal,_with_variable_foci_1|Familial_focal_epilepsy_with_variable_foci|Inborn_genetic_diseases|not_provided|DEPDC5-related_disorder. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007295,MedGen:C0376532,Orphanet:1945|MONDO:MONDO:0024556,MedGen:C4551983,OMIM:604364|MONDO:MONDO:0020310,MedGen:C1858477,OMIM:PS604364,Orphanet:98820|MeSH:D030342,MedGen:C0950123|MedGen:C3661900|.. Review status: criteria provided, multiple submitters, no conflicts.