A: The variant NC_000021.9:g.44525659G>A in gene TSPEAR is classified as 'Uncertain_significance' for Tooth_agenesis,_selective,_10|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0859339,MedGen:C5774277,OMIM:620173|MedGen:C3661900. Review status: criteria provided, single submitter.