A: The variant NC_000019.10:g.18783177C>T in gene COMP is classified as 'Uncertain_significance' for Carpal_tunnel_syndrome_2. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030883,MedGen:C5436916,OMIM:619161. Review status: criteria provided, single submitter.