A: The variant NC_000021.9:g.31663848A>G in gene SOD1 is classified as 'Pathogenic' for Amyotrophic_lateral_sclerosis_type_1|SOD1-related_disorder|Amyotrophic_lateral_sclerosis_type_10|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803|.|MONDO:MONDO:0012790,MedGen:C2677565,OMIM:612069,Orphanet:275872,Orphanet:803|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.