A: The variant NC_000019.10:g.45358898A>G in gene ERCC2 is classified as 'Uncertain_significance' for Xeroderma_pigmentosum,_group_C. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010211,MedGen:C2752147,OMIM:278720,Orphanet:910. Review status: criteria provided, single submitter.