A: The variant NC_000019.10:g.41389847A>G in gene EXOSC5 is classified as 'Uncertain_significance' for Cerebellar_ataxia,_brain_abnormalities,_and_cardiac_conduction_defects|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0859200,MedGen:C5562005,OMIM:619576,Orphanet:641361|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.