A: The variant NC_000019.10:g.48238462C>T in gene CARD8 is classified as 'Uncertain_significance' for not_specified|Inflammatory_bowel_disease_30. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0033643,MedGen:C5436750,OMIM:619079. Review status: criteria provided, single submitter.