A: The variant NC_000022.11:g.24523729G>A in gene UPB1 is classified as 'Uncertain_significance' for Deficiency_of_beta-ureidopropionase. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013164,MedGen:C1291512,OMIM:613161,Orphanet:65287. Review status: criteria provided, single submitter.