A: The variant NC_000022.11:g.36292059T>C in gene MYH9 is classified as 'Likely_pathogenic' for Numerous_pigmented_freckles|Hypertensive_disorder|Abnormal_platelet_function|Abnormal_platelet_morphology|Increased_mean_platelet_volume|Abnormal_platelet_shape|Thrombocytopenia|Obesity|Abnormal_facial_shape|Epistaxis|MYH9-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0007587,MedGen:C1968565|Human_Phenotype_Ontology:HP:0000822,Human_Phenotype_Ontology:HP:0004949,Human_Phenotype_Ontology:HP:0005126,MONDO:MONDO:0005044,MedGen:C0020538|Human_Phenotype_Ontology:HP:0011869,MedGen:C0855740|Human_Phenotype_Ontology:HP:0011875,MedGen:C0855742|Human_Phenotype_Ontology:HP:0011877,MedGen:C1096367|Human_Phenotype_Ontology:HP:0012524,MedGen:C4022866|Human_Phenotype_Ontology:HP:0001873,Human_Phenotype_Ontology:HP:0001906,Human_Phenotype_Ontology:HP:0004838,Human_Phenotype_Ontology:HP:0008175,Human_Phenotype_Ontology:HP:0008268,Human_Phenotype_Ontology:HP:0008302,MONDO:MONDO:0002049,MeSH:D013921,MedGen:C0040034|Human_Phenotype_Ontology:HP:0001513,MONDO:MONDO:0011122,MeSH:D009765,MedGen:C0028754,Orphanet:71529|Human_Phenotype_Ontology:HP:0001999,Human_Phenotype_Ontology:HP:0002004,Human_Phenotype_Ontology:HP:0002260,Human_Phenotype_Ontology:HP:0004643,Human_Phenotype_Ontology:HP:0004649,Human_Phenotype_Ontology:HP:0004652,Human_Phenotype_Ontology:HP:0004655,Human_Phenotype_Ontology:HP:0004675,Human_Phenotype_Ontology:HP:0005124,MedGen:C0424503|Human_Phenotype_Ontology:HP:0000421,MedGen:C0014591|MedGen:C1854520. Review status: criteria provided, multiple submitters, no conflicts.