A: The variant NC_000019.10:g.38587363G>C in gene RYR1 is classified as 'Uncertain_significance' for Malignant_hyperthermia_of_anesthesia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0034733,MONDO:MONDO:0018493,MedGen:C0024591,Orphanet:423. Review status: reviewed by expert panel.