A: The variant NC_000022.11:g.28724974_28725249del in gene CHEK2 is classified as 'Uncertain_significance' for Familial_ovarian_cancer. Molecular consequence: SO:0001574: splice_acceptor_variant,SO:0001575: splice_donor_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0016248,MedGen:C5679802,Orphanet:213517. Review status: no assertion criteria provided.