A: The variant NC_000022.11:g.50625396G>T in gene ARSA is classified as 'Pathogenic' for Metachromatic_leukodystrophy,_juvenile_type. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009591,MedGen:C0751276,Orphanet:309263. Review status: no assertion criteria provided.