A: The variant NC_000022.11:g.41517625C>T in gene ACO2 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Isolated_macular_dystrophy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0957048,MedGen:C5681367,Orphanet:519302. Review status: criteria provided, conflicting classifications.