A: The variant NC_000019.10:g.49830911_49830929dup in gene MED25 is classified as 'Benign' for Charcot-Marie-Tooth_disease_type_2|Charcot-Marie-Tooth_disease|Congenital_cataract-microcephaly-nevus_flammeus_simplex-severe_intellectual_disability_syndrome. Molecular consequence: SO:0001627: intron_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0018993,MedGen:C0270914,Orphanet:64746|MONDO:MONDO:0015626,MedGen:C0007959,OMIM:PS118220,Orphanet:166|MONDO:MONDO:0014643,MedGen:C4225323,OMIM:616449,Orphanet:464738. Review status: criteria provided, multiple submitters, no conflicts.