A: The variant NC_000022.11:g.28687890A>G in gene CHEK2 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Familial_cancer_of_breast|Hereditary_cancer-predisposing_syndrome|Malignant_tumor_of_breast|not_specified. Molecular consequence: SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480,Orphanet:227535|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MONDO:MONDO:0007254,MedGen:C0006142|MedGen:CN169374. Review status: criteria provided, conflicting classifications.