A: The variant NC_000021.9:g.43063920_43063922del in gene CBS is classified as 'Conflicting_classifications_of_pathogenicity' for Classic_homocystinuria|HYPERHOMOCYSTEINEMIA,_THROMBOTIC,_CBS-RELATED. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MONDO:MONDO:0009352,MedGen:C0751202,OMIM:236200,Orphanet:394|MedGen:C3150344. Review status: criteria provided, conflicting classifications.