A: The variant NC_000021.9:g.33421550G>C in gene IFNGR2 is classified as 'Uncertain_significance' for Immunodeficiency_28. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013953,MedGen:C4013947,OMIM:614889,Orphanet:319547,Orphanet:319574. Review status: criteria provided, single submitter.