A: The variant NC_000020.11:g.35437412T>C in gene GDF5 is classified as 'Pathogenic' for Brachydactyly_type_C. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0009373,MONDO:MONDO:0007221,MedGen:C1862103,OMIM:113100,Orphanet:93384. Review status: no assertion criteria provided.