A: The variant NC_000019.10:g.15540514C>T in gene CYP4F22 is classified as 'Uncertain_significance' for CYP4F22-related_disorder|not_provided|Autosomal_recessive_congenital_ichthyosis_5. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:C3661900|Gene:50992,MONDO:MONDO:0011485,MedGen:C1858133,OMIM:604777,Orphanet:313. Review status: criteria provided, multiple submitters, no conflicts.