A: The variant NC_000019.10:g.16977435dup in gene CPAMD8 is classified as 'Likely_pathogenic' for Abnormal_anterior_eye_segment_morphology. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: Human_Phenotype_Ontology:HP:0004328,MedGen:C4025355. Review status: criteria provided, single submitter.