A: The variant NC_000022.11:g.46356875G>T in gene TRMU is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|not_specified|TRMU-related_disorder|Acute_infantile_liver_failure_due_to_synthesis_defect_of_mtDNA-encoded_proteins|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MedGen:CN169374|.|MONDO:MONDO:0013111,MedGen:C3278664,OMIM:613070,Orphanet:217371|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, conflicting classifications.