A: The variant NC_000021.9:g.37480761_37480776del in gene DYRK1A is classified as 'Pathogenic' for Complex_neurodevelopmental_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0100038,MedGen:C5568766,Orphanet:528084. Review status: no assertion criteria provided.