A: The variant NC_000019.10:g.48162272G>T in gene LIG1 is classified as 'Uncertain_significance' for Immunodeficiency_96. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030693,MedGen:C5676930,OMIM:619774. Review status: criteria provided, single submitter.