A: The variant NC_000020.11:g.4699600G>T in gene PRNP is classified as 'protective' for Kuru,_protection_against. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C4016338. Review status: no assertion criteria provided.