A: The variant NC_000019.10:g.44908718A>G in gene APOE is classified as 'Uncertain_significance' for Familial_type_3_hyperlipoproteinemia|Familial_hypercholesterolemia|Hyperlipoproteinemia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0018473,MedGen:C0020479,OMIM:617347,Orphanet:412|MONDO:MONDO:0005439,MedGen:C0020445,OMIM:PS143890|Human_Phenotype_Ontology:HP:0010980,MONDO:MONDO:0037748,MedGen:C0020476. Review status: no assertion criteria provided.