A: The variant NC_000021.9:g.37512452_37512457delinsAGAG in gene DYRK1A is classified as 'Likely_pathogenic' for not_provided. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Indel. Disease database links: MedGen:CN517202. Review status: criteria provided, single submitter.