A: The variant NC_000019.10:g.38486071G>A in gene RYR1 is classified as 'Uncertain_significance' for Malignant_hyperthermia,_susceptibility_to,_1. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423. Review status: criteria provided, single submitter.