A: The variant NC_000020.11:g.49036004_49036005dup in gene ARFGEF2 is classified as 'Uncertain_significance' for not_provided|Periventricular_laminar_heterotopia. Molecular consequence: SO:0001624: 3_prime_UTR_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|Human_Phenotype_Ontology:HP:0032389,MedGen:C2678104. Review status: criteria provided, multiple submitters, no conflicts.