A: The variant NC_000022.11:g.18921389C>T in gene PRODH is classified as 'Uncertain_significance' for Proline_dehydrogenase_deficiency|Schizophrenia_4. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009400,MedGen:C0268529,OMIM:239500,Orphanet:419|MONDO:MONDO:0010943,MedGen:C1833247,OMIM:600850. Review status: criteria provided, multiple submitters, no conflicts.