A: The variant NC_000020.11:g.13785272del in gene NDUFAF5 is classified as 'Pathogenic/Likely_pathogenic' for Mitochondrial_complex_1_deficiency,_nuclear_type_16|not_provided. Molecular consequence: SO:0001589: frameshift_variant,SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0032621,MedGen:C4748785,OMIM:618238|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.