A: The variant NC_000019.10:g.49016130C>T in gene LHB is classified as 'Likely_benign' for not_provided|Isolated_lutropin_deficiency|Variant_of_unknown_significance. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0009223,MedGen:C0271582,OMIM:228300,Orphanet:325448|MedGen:C2986382. Review status: criteria provided, multiple submitters, no conflicts.