A: The variant NC_000022.11:g.36476744T>C in gene TXN2 is classified as 'Uncertain_significance' for not_provided|not_specified|Combined_oxidative_phosphorylation_deficiency_29. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MedGen:CN169374|MONDO:MONDO:0014781,MedGen:C5567607,OMIM:616811,Orphanet:478029. Review status: criteria provided, multiple submitters, no conflicts.