A: The variant NC_000019.10:g.40374524T>C in gene PLD3 is classified as 'Uncertain_significance' for Spinocerebellar_ataxia_46. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0033481,MedGen:C4540404,OMIM:617770,Orphanet:589522. Review status: criteria provided, single submitter.