A: The variant NC_000019.10:g.15160941dup in gene NOTCH3 is classified as 'Pathogenic' for not_provided|Lateral_meningocele_syndrome. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MedGen:C3661900|MONDO:MONDO:0007537,MedGen:C1851710,OMIM:130720,Orphanet:2789. Review status: criteria provided, multiple submitters, no conflicts.