A: The variant NC_000019.10:g.44908529G>T in gene APOE is classified as 'Uncertain_significance' for Familial_hypercholesterolemia. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0005439,MedGen:C0020445,OMIM:PS143890. Review status: no assertion criteria provided.