A: The variant NC_000020.11:g.45898368G>T in gene CTSA is classified as 'Uncertain_significance' for Inborn_genetic_diseases|Combined_deficiency_of_sialidase_AND_beta_galactosidase. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0009737,MedGen:C0268233,OMIM:256540,Orphanet:351. Review status: criteria provided, multiple submitters, no conflicts.