A: The variant NC_000020.11:g.32795501G>A in gene DNMT3B is classified as 'Conflicting_classifications_of_pathogenicity' for Centromeric_instability_of_chromosomes_1,9_and_16_and_immunodeficiency|Immunodeficiency-centromeric_instability-facial_anomalies_syndrome_1|Facioscapulohumeral_muscular_dystrophy_4,_digenic|Inborn_genetic_diseases|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0000133,MedGen:C0398788,OMIM:PS242860,Orphanet:2268|MONDO:MONDO:0009454,MedGen:C4551557,OMIM:242860,Orphanet:2268|MONDO:MONDO:0030355,MedGen:C5561960,OMIM:619478|MeSH:D030342,MedGen:C0950123|MedGen:C3661900. Review status: criteria provided, conflicting classifications.