A: The variant NC_000021.9:g.44509290G>A in gene TSPEAR is classified as 'Pathogenic' for Tooth_agenesis,_selective,_10. Molecular consequence: SO:0001587: nonsense,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0859339,MedGen:C5774277,OMIM:620173. Review status: no assertion criteria provided.