A: The variant NC_000022.11:g.50698780_50698785dup in gene SHANK3 is classified as 'Uncertain_significance' for Inborn_genetic_diseases. Molecular consequence: SO:0001820: inframe_indel,SO:0001821: inframe_insertion. Variant type: Duplication. Disease database links: MeSH:D030342,MedGen:C0950123. Review status: criteria provided, single submitter.