A: The variant NC_000019.10:g.45768818_45768829del in gene SIX5 is classified as 'Uncertain_significance' for Branchiootorenal_syndrome_2. Variant type: Deletion. Disease database links: MONDO:MONDO:0012575,MedGen:C1970479,OMIM:610896,Orphanet:107. Review status: criteria provided, single submitter.