A: The variant NC_000021.9:g.45456745G>C in gene COL18A1 is classified as 'Likely_benign' for COL18A1-related_disorder. Molecular consequence: SO:0001627: intron_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: .. Review status: no assertion criteria provided.