A: The variant NC_000019.10:g.38459264del in gene RYR1 is classified as 'Likely_pathogenic' for Hydrops_fetalis. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: Human_Phenotype_Ontology:HP:0001789,MONDO:MONDO:0015193,MedGen:C0020305,Orphanet:1041. Review status: criteria provided, single submitter.