A: The variant NC_000022.11:g.37143520C>T in gene IL2RB is classified as 'Uncertain_significance' for Immunodeficiency_63_with_lymphoproliferation_and_autoimmunity. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0032782,MedGen:C5193126,OMIM:618495. Review status: criteria provided, single submitter.