A: The variant NC_000022.11:g.20990410_20990430dup in gene LZTR1 is classified as 'Uncertain_significance' for Inborn_genetic_diseases|Hereditary_cancer-predisposing_syndrome|Cardiovascular_phenotype. Molecular consequence: SO:0001821: inframe_insertion. Variant type: Duplication. Disease database links: MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MedGen:CN230736. Review status: criteria provided, single submitter.