A: The variant NC_000022.11:g.50625260_50625270del in gene ARSA is classified as 'Pathogenic' for Metachromatic_leukodystrophy,_late_infantile_form|not_provided|Metachromatic_leukodystrophy. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0017729,MedGen:C0751278,Orphanet:309256|MedGen:C3661900|MONDO:MONDO:0018868,MedGen:C0023522,OMIM:250100,Orphanet:512. Review status: criteria provided, single submitter.