A: The variant NC_000022.11:g.41520176G>A in gene ACO2 is classified as 'Likely_benign' for not_provided|ACO2-related_disorder|Optic_atrophy_9|Infantile_cerebellar-retinal_degeneration. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|.|MONDO:MONDO:0014571,MedGen:C4225384,OMIM:616289|MONDO:MONDO:0013802,MedGen:C3281192,OMIM:614559,Orphanet:313850. Review status: criteria provided, multiple submitters, no conflicts.