A: The variant NC_000019.10:g.49167957A>G in gene TRPM4 is classified as 'Conflicting_classifications_of_pathogenicity' for Progressive_familial_heart_block_type_IB|Brugada_syndrome|not_provided|Cardiovascular_phenotype|TRPM4-related_disorder|not_specified. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871|MONDO:MONDO:0015263,MedGen:C1142166,OMIM:PS601144,Orphanet:130|MedGen:C3661900|MedGen:CN230736|MedGen:CN239424|MedGen:CN169374. Review status: criteria provided, conflicting classifications.