A: The variant NC_000020.11:g.58903569del in gene GNAS is classified as 'Pathogenic' for Pseudohypoparathyroidism_type_1B. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0011301,MedGen:C1864100,OMIM:603233,Orphanet:94089. Review status: criteria provided, single submitter.