A: The variant NC_000019.10:g.15243267_15243275del in gene BRD4 is classified as 'Uncertain_significance' for not_provided|De_Lange_syndrome. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MedGen:C3661900|MONDO:MONDO:0016033,MedGen:C0270972,OMIM:PS122470,Orphanet:199. Review status: criteria provided, multiple submitters, no conflicts.