A: The variant NC_000019.10:g.51024783C>T in gene KLK11 is classified as 'Pathogenic' for Ichthyosis_with_erythrokeratoderma. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957783,MedGen:C5882691,OMIM:620507. Review status: no assertion criteria provided.