A: The variant NC_000019.10:g.38561398_38561406del in gene RYR1 is classified as 'Uncertain_significance' for not_provided|Central_core_myopathy|RYR1-related_disorder. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MedGen:C3661900|MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|MedGen:CN239331. Review status: criteria provided, multiple submitters, no conflicts.