A: The variant NC_000021.9:g.37490215_37490217delinsAC in gene DYRK1A is classified as 'Pathogenic' for Complex_neurodevelopmental_disorder|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: Indel. Disease database links: MONDO:MONDO:0100038,MedGen:C5568766,Orphanet:528084|MedGen:C3661900. Review status: criteria provided, single submitter.