A: The variant NC_000019.10:g.38510518C>T in gene RYR1 is classified as 'Pathogenic/Likely_pathogenic' for Central_core_myopathy|RYR1-related_disorder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|MedGen:CN239331. Review status: criteria provided, multiple submitters, no conflicts.