A: The variant NC_000020.11:g.25076320C>A in gene VSX1 is classified as 'Uncertain_significance' for not_provided|Keratoconus_1|Craniofacial_anomalies_and_anterior_segment_dysgenesis_syndrome. Molecular consequence: SO:0001587: nonsense,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0007851,MedGen:C1835677,OMIM:148300|MONDO:MONDO:0013618,MedGen:C3280099,OMIM:614195. Review status: criteria provided, multiple submitters, no conflicts.