A: The variant NC_000019.10:g.45494278_45494279dup in gene RTN2 is classified as 'Pathogenic' for Neuronopathy,_distal_hereditary_motor,_autosomal_recessive_11,_with_spasticity. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0971150,MedGen:C5935630,OMIM:620854. Review status: no assertion criteria provided.