A: The variant NC_000019.10:g.40397504A>C in gene PRX is classified as 'Uncertain_significance' for Charcot-Marie-Tooth_disease_type_4F|Charcot-Marie-Tooth_disease|Charcot-Marie-Tooth_disease_type_4|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013959,MedGen:C3540453,OMIM:614895,Orphanet:99952|MONDO:MONDO:0015626,MedGen:C0007959,OMIM:PS118220,Orphanet:166|MONDO:MONDO:0018995,MedGen:C4082197,Orphanet:64749|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.