A: The variant NC_000022.11:g.18921419_18921420inv in gene PRODH is classified as 'Uncertain_significance' for not_provided|Proline_dehydrogenase_deficiency. Molecular consequence: SO:0001583: missense_variant. Variant type: Inversion. Disease database links: MedGen:C3661900|MONDO:MONDO:0009400,MedGen:C0268529,OMIM:239500,Orphanet:419. Review status: criteria provided, single submitter.