A: The variant NC_000019.10:g.42249415G>A in gene ERF is classified as 'Pathogenic' for Inborn_genetic_diseases|Craniosynostosis_4|not_provided|Noonan_Syndrome-like_developmental_disorder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|Human_Phenotype_Ontology:HP:0004443,Human_Phenotype_Ontology:HP:0004486,MONDO:MONDO:0010929,MedGen:C1833340,OMIM:600775|MedGen:C3661900|.. Review status: criteria provided, multiple submitters, no conflicts.