A: The variant NC_000019.10:g.43526626G>C in gene ETHE1 is classified as 'Uncertain_significance' for Ethylmalonic_encephalopathy|Inborn_genetic_diseases|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001623: 5_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011229,MedGen:C1865349,OMIM:602473,Orphanet:51188|MeSH:D030342,MedGen:C0950123|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.