A: The variant NC_000021.9:g.46227716_46227717del in gene LSS is classified as 'Benign' for Alopecia-intellectual_disability_syndrome_4|Cataract_44|not_provided. Molecular consequence: SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0030009,MedGen:C5394241,OMIM:618840|MONDO:MONDO:0014673,MedGen:C4225300,OMIM:616509,Orphanet:91492,Orphanet:98994|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.