A: The variant NC_000022.11:g.18922933G>A in gene PRODH is classified as 'Uncertain_significance' for Proline_dehydrogenase_deficiency|not_specified. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009400,MedGen:C0268529,OMIM:239500,Orphanet:419|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.