A: The variant NC_000019.10:g.49016635_49016643del in gene LHB is classified as 'Pathogenic' for Isolated_lutropin_deficiency. Molecular consequence: SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MONDO:MONDO:0009223,MedGen:C0271582,OMIM:228300,Orphanet:325448. Review status: no assertion criteria provided.