A: The variant NC_000019.10:g.46412768G>A in gene CCDC8 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|3M_syndrome_3|CCDC8-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0013627,MedGen:C3280146,OMIM:614205,Orphanet:2616|.. Review status: criteria provided, conflicting classifications.