A: The variant NC_000020.11:g.4699856G>A in gene PRNP is classified as 'Likely_benign' for Huntington_disease-like_1|Inherited_Creutzfeldt-Jakob_disease|Gerstmann-Straussler-Scheinker_syndrome|Fatal_familial_insomnia|Spongiform_encephalopathy_with_neuropsychiatric_features|Kuru,_susceptibility_to. Molecular consequence: SO:0001624: 3_prime_UTR_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011299,MedGen:C1864112,OMIM:603218,Orphanet:157941|MONDO:MONDO:0007403,MedGen:C0751254,OMIM:123400,Orphanet:204,Orphanet:282166,Orphanet:454700|MONDO:MONDO:0007656,MedGen:C0017495,OMIM:137440,Orphanet:356|MONDO:MONDO:0010808,MedGen:C0206042,OMIM:600072,Orphanet:466|MONDO:MONDO:0011703,MedGen:C1847650,OMIM:606688|MONDO:MONDO:0009500,MedGen:C1855588,OMIM:245300,Orphanet:454745. Review status: criteria provided, multiple submitters, no conflicts.