A: The variant NC_000022.11:g.41515536G>T in gene ACO2 is classified as 'Pathogenic/Likely_pathogenic' for not_provided|ACO2-related_disorder. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|.. Review status: criteria provided, multiple submitters, no conflicts.