A: The variant NC_000022.11:g.37978083G>A in gene SOX10 is classified as 'Pathogenic/Likely_pathogenic' for not_provided|Deafness_with_anatomical_inner_ear_anomalies|Waardenburg_syndrome_type_4C|PCWH_syndrome|Waardenburg_syndrome_type_2E. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|.|MONDO:MONDO:0013202,MedGen:C2750452,OMIM:613266,Orphanet:897|MONDO:MONDO:0012198,MedGen:C1836727,OMIM:609136,Orphanet:163746|MONDO:MONDO:0012698,MedGen:C2700405,OMIM:611584,Orphanet:3440. Review status: criteria provided, multiple submitters, no conflicts.