A: The variant NC_000019.10:g.29702746T>G in gene C19orf12 is classified as 'Benign' for not_specified|not_provided|Hereditary_spastic_paraplegia_43|Hereditary_spastic_paraplegia|Neurodegeneration_with_brain_iron_accumulation_4. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MedGen:C3661900|MONDO:MONDO:0014024,MedGen:C2680446,OMIM:615043,Orphanet:320370|MONDO:MONDO:0019064,MedGen:C0037773,OMIM:PS303350,Orphanet:685|MONDO:MONDO:0013674,MedGen:C3280371,OMIM:614298,Orphanet:289560. Review status: criteria provided, multiple submitters, no conflicts.