A: The variant NC_000020.11:g.63361112_63361117dup in gene CHRNA4 is classified as 'Uncertain_significance' for not_provided|Autosomal_dominant_nocturnal_frontal_lobe_epilepsy. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant,SO:0001821: inframe_insertion. Variant type: Duplication. Disease database links: MedGen:C3661900|MONDO:MONDO:0020300,MedGen:C3696898,Orphanet:98784. Review status: criteria provided, multiple submitters, no conflicts.