A: The variant NC_000019.10:g.16485172G>T in gene CALR3 is classified as 'Benign' for not_provided|not_specified|Hypertrophic_cardiomyopathy_19|CALR3-related_disorder. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MedGen:CN169374|MONDO:MONDO:0013476,MedGen:CN077603|.. Review status: criteria provided, multiple submitters, no conflicts.