A: The variant NC_000020.11:g.36927231_36927232del in gene SAMHD1 is classified as 'Pathogenic/Likely_pathogenic' for Aicardi-Goutieres_syndrome_5|Chilblain_lupus_2|not_provided. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0013059,MedGen:C2749659,OMIM:612952,Orphanet:51|MONDO:MONDO:0013739,MedGen:C3280721,OMIM:614415|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.