A: The variant NC_000021.9:g.44531087G>A in gene TSPEAR is classified as 'Pathogenic/Likely_pathogenic' for TSPEAR-related_disorder|Inborn_genetic_diseases|not_specified|Ectodermal_dysplasia_14,_hair/tooth_type_with_or_without_hypohidrosis|TSPEAR-related_disorder_of_tooth_and_hair_follicle_morphogenesis|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: .|MeSH:D030342,MedGen:C0950123|MedGen:CN169374|MONDO:MONDO:0032584,MedGen:C4748560,OMIM:618180|.|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.