A: The variant NC_000020.11:g.59024172G>C in gene TUBB1 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Macrothrombocytopenia,_isolated,_1,_autosomal_dominant|TUBB1-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0800047,MedGen:C5676892,OMIM:613112,Orphanet:140957|.. Review status: criteria provided, conflicting classifications.