A: The variant NC_000022.11:g.25207123G>T in gene CRYBB3 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Cataract_22_multiple_types|CRYBB3-related_disorder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0012336,MedGen:C1857853,OMIM:609741,Orphanet:91492|.. Review status: criteria provided, conflicting classifications.