A: The variant NC_000022.11:g.20055980C>T in gene TANGO2 is classified as 'Pathogenic' for Metabolic_crises_with_rhabdomyolysis,_cardiac_arrhythmias,_and_neurodegeneration|Recurrent_metabolic_encephalomyopathic_crises-rhabdomyolysis-cardiac_arrhythmia-intellectual_disability_syndrome|not_provided. Molecular consequence: SO:0001587: nonsense,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: .|MONDO:MONDO:0018820,MedGen:C5567524,OMIM:616878,Orphanet:480864|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.