A: The variant NC_000019.10:g.38505980C>T in gene RYR1 is classified as 'Benign' for Congenital_multicore_myopathy_with_external_ophthalmoplegia|not_specified|King_Denborough_syndrome|not_provided|Central_core_myopathy. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0003789,Human_Phenotype_Ontology:HP:0003804,MONDO:MONDO:0009712,MedGen:C1850674,OMIM:255320,Orphanet:598,Orphanet:98905|MedGen:CN169374|MONDO:MONDO:0020485,MedGen:C1840365,OMIM:619542|MedGen:C3661900|MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597. Review status: criteria provided, multiple submitters, no conflicts.