A: The variant NC_000019.10:g.42408113_42408114dup in gene LIPE is classified as 'Pathogenic' for LIPE-related_familial_partial_lipodystrophy. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0014431,MedGen:C4014869,OMIM:615980,Orphanet:435660. Review status: no assertion criteria provided.