A: The variant NC_000019.10:g.16496127_16496144del in gene CALR3 is classified as 'Uncertain_significance' for Hypertrophic_cardiomyopathy_19. Molecular consequence: SO:0001582: initiator_codon_variant,SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MONDO:MONDO:0013476,MedGen:CN077603. Review status: criteria provided, single submitter.