A: The variant NC_000023.11:g.12920335C>T in gene TLR8 is classified as 'Uncertain_significance' for TLR8-related_condition|Immunodeficiency_98_with_autoinflammation,_X-linked|INFLTR8|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: .|MONDO:MONDO:0024777,MedGen:C5676883,OMIM:301078,Orphanet:675628|.|MedGen:C3661900. Review status: criteria provided, single submitter.