A: The variant NC_000019.10:g.45552543del in gene OPA3 is classified as 'Benign' for Optic_Atrophy,_Dominant|3-Methylglutaconic_aciduria_type_3. Molecular consequence: SO:0001624: 3_prime_UTR_variant,SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MedGen:CN239213|MONDO:MONDO:0009787,MedGen:C0574084,OMIM:258501,Orphanet:67047. Review status: criteria provided, single submitter.