A: The variant NC_000019.10:g.48230620C>A in gene CARD8 is classified as 'Uncertain_significance' for not_provided|Inflammatory_bowel_disease_30. Molecular consequence: SO:0001587: nonsense,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0033643,MedGen:C5436750,OMIM:619079. Review status: criteria provided, multiple submitters, no conflicts.