A: The variant NC_000019.10:g.16482518C>T in gene CALR3 is classified as 'Benign/Likely_benign' for not_specified|Hypertrophic_cardiomyopathy|Cardiomyopathy|Cardiovascular_phenotype|not_provided|Hypertrophic_cardiomyopathy_19. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|Human_Phenotype_Ontology:HP:0001639,MONDO:MONDO:0005045,MeSH:D002312,MedGen:C0007194,Orphanet:217569|Human_Phenotype_Ontology:HP:0001638,MONDO:MONDO:0004994,MedGen:C0878544,Orphanet:167848|MedGen:CN230736|MedGen:C3661900|MONDO:MONDO:0013476,MedGen:CN077603. Review status: criteria provided, multiple submitters, no conflicts.