A: The variant NC_000019.10:g.35904415A>G in gene TYROBP is classified as 'Uncertain_significance' for Polycystic_lipomembranous_osteodysplasia_with_sclerosing_leukoencephalopathy_1. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0020749,MedGen:C4721893,OMIM:221770,Orphanet:2770. Review status: criteria provided, single submitter.