A: The variant NC_000020.11:g.35654277T>A in gene CPNE1 is classified as 'Uncertain_significance' for Neurodevelopmental_delay. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0012758,MedGen:C4022738. Review status: criteria provided, single submitter.