A: The variant NC_000019.10:g.19516282dup in gene NDUFA13 is classified as 'Likely_pathogenic' for Mitochondrial_complex_1_deficiency,_nuclear_type_28|Hurthle_cell_carcinoma_of_thyroid. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0032632,MedGen:C4748827,OMIM:618249|MONDO:MONDO:0011836,MedGen:C0749424,OMIM:607464,Orphanet:146. Review status: criteria provided, single submitter.