A: The variant NC_000019.10:g.15548182T>C in gene CYP4F22 is classified as 'Uncertain_significance' for Atopic_eczema|Ichthyosis. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0001047,Human_Phenotype_Ontology:HP:0007533,Human_Phenotype_Ontology:HP:0007564,MONDO:MONDO:0004980,MedGen:C0011615,OMIM:PS603165|Human_Phenotype_Ontology:HP:0000955,Human_Phenotype_Ontology:HP:0007547,Human_Phenotype_Ontology:HP:0008064,MONDO:MONDO:0019269,MedGen:C0020757,Orphanet:79354. Review status: criteria provided, single submitter.