A: The variant NC_000020.11:g.35434276C>T in gene GDF5 is classified as 'Pathogenic/Likely_pathogenic' for Grebe_syndrome|Type_A2_brachydactyly|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0008703,MedGen:C0265260,OMIM:200700,Orphanet:2098|Human_Phenotype_Ontology:HP:0009372,MONDO:MONDO:0007216,MedGen:C1832702,OMIM:112600,Orphanet:93396|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.