A: The variant NC_000019.10:g.45028920C>T in gene RELB is classified as 'Likely_pathogenic' for Immunodeficiency_53. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0054696,MedGen:C4539811,OMIM:617585. Review status: criteria provided, single submitter.