A: The variant NC_000021.9:g.43416922C>T in gene SIK1 is classified as 'Likely_benign' for Developmental_and_epileptic_encephalopathy,_30. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014595,MedGen:C4225360,OMIM:616341. Review status: criteria provided, single submitter.