A: The variant NC_000020.11:g.10413051C>T in gene MKKS is classified as 'Uncertain_significance' for McKusick-Kaufman_syndrome|Bardet-Biedl_syndrome_6|MKKS-related_disorder|Retinal_dystrophy|Inborn_genetic_diseases|Bardet-Biedl_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009367,MedGen:C0948368,OMIM:236700,Orphanet:2473|MONDO:MONDO:0011523,MedGen:C1858054,OMIM:605231,Orphanet:110|.|Human_Phenotype_Ontology:HP:0000556,Human_Phenotype_Ontology:HP:0007736,Human_Phenotype_Ontology:HP:0007910,Human_Phenotype_Ontology:HP:0007974,Human_Phenotype_Ontology:HP:0007982,MONDO:MONDO:0019118,MeSH:D058499,MedGen:C0854723,Orphanet:71862|MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0015229,MedGen:C0752166,OMIM:PS209900,Orphanet:110. Review status: criteria provided, multiple submitters, no conflicts.