A: The variant NC_000020.11:g.25077753G>C in gene VSX1 is classified as 'Conflicting_classifications_of_pathogenicity' for Keratoconus_1|Craniofacial_anomalies_and_anterior_segment_dysgenesis_syndrome|Polymorphous_corneal_dystrophy|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007851,MedGen:C1835677,OMIM:148300|MONDO:MONDO:0013618,MedGen:C3280099,OMIM:614195|Human_Phenotype_Ontology:HP:0007915,MONDO:MONDO:0020364,MedGen:C0339284,OMIM:PS122000,Orphanet:98973|MedGen:C3661900. Review status: criteria provided, conflicting classifications.