A: The variant NC_000022.11:g.50526673C>T in gene TYMP is classified as 'Benign/Likely_benign' for Mitochondrial_DNA_depletion_syndrome_1|Mitochondrial_neurogastrointestinal_encephalomyopathy|Fatal_Infantile_Cardioencephalomyopathy|not_specified|Mitochondrial_complex_IV_deficiency,_nuclear_type_1|not_provided. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011283,MedGen:C4551995,OMIM:603041,Orphanet:298|MONDO:MONDO:0017575,MedGen:C0872218,Orphanet:298|MedGen:CN239235|MedGen:CN169374|MONDO:MONDO:0700250,MedGen:C5435656,OMIM:220110|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.