A: The variant NC_000019.10:g.29708290C>T in gene C19orf12 is classified as 'Conflicting_classifications_of_pathogenicity' for Hereditary_spastic_paraplegia|Brain_iron_accummulation|Neurodegeneration|Hereditary_spastic_paraplegia_43|Neurodegeneration_with_brain_iron_accumulation|not_provided. Molecular consequence: SO:0001583: missense_variant,SO:0001623: 5_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0019064,MedGen:C0037773,OMIM:PS303350,Orphanet:685|MedGen:CN228270|Human_Phenotype_Ontology:HP:0002180,MONDO:MONDO:0005559,MedGen:C0027746|MONDO:MONDO:0014024,MedGen:C2680446,OMIM:615043,Orphanet:320370|MONDO:MONDO:0018307,MedGen:C2931845,OMIM:PS234200,Orphanet:385|MedGen:C3661900. Review status: criteria provided, conflicting classifications.