A: The variant NC_000023.11:g.15331789C>T in gene PIGA is classified as 'Uncertain_significance' for Paroxysmal_nocturnal_hemoglobinuria_1. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010438,MedGen:C3806670,OMIM:300818,Orphanet:447. Review status: no assertion criteria provided.