A: The variant NC_000022.11:g.20779633dup in gene SERPIND1 is classified as 'Pathogenic' for Heparin_cofactor_II_deficiency. Molecular consequence: SO:0001589: frameshift_variant,SO:0001627: intron_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0012876,MedGen:C0398626,OMIM:612356. Review status: no assertion criteria provided.