A: The variant NC_000021.9:g.25698786G>C in gene JAM2 is classified as 'Pathogenic' for Basal_ganglia_calcification,_idiopathic,_8,_autosomal_recessive. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0032938,MedGen:C5394199,OMIM:618824. Review status: no assertion criteria provided.