A: The variant NC_000021.9:g.43066279C>T in gene CBS is classified as 'Conflicting_classifications_of_pathogenicity' for not_specified|Homocystinuria,_pyridoxine-responsive|HYPERHOMOCYSTEINEMIA,_THROMBOTIC,_CBS-RELATED. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MedGen:C3502110|MedGen:C3150344. Review status: criteria provided, conflicting classifications.