A: The variant NC_000020.11:g.58910740G>T in gene GNAS is classified as 'Pathogenic' for PSEUDOHYPOPARATHYROIDISM,_TYPE_IA,_WITH_TESTOTOXICOSIS. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C4016140. Review status: no assertion criteria provided.