A: The variant NC_000021.9:g.45176110_45176112del in gene ADARB1 is classified as 'Uncertain_significance' for Neurodevelopmental_disorder_with_hypotonia,_microcephaly,_and_seizures. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001820: inframe_indel,SO:0001822: inframe_deletion. Variant type: Deletion. Disease database links: MONDO:MONDO:0030025,MedGen:C5394312,OMIM:618862. Review status: criteria provided, single submitter.