A: The variant NC_000021.9:g.42375728G>A in gene TMPRSS3 is classified as 'Conflicting_classifications_of_pathogenicity' for Autosomal_recessive_nonsyndromic_hearing_loss_8|not_specified|not_provided|TMPRSS3-related_disorder. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010987,MedGen:C1832827,OMIM:601072,Orphanet:90636|MedGen:CN169374|MedGen:C3661900|.. Review status: criteria provided, conflicting classifications.