A: The variant NC_000021.9:g.42486421G>C in gene RSPH1 is classified as 'Pathogenic' for Primary_ciliary_dyskinesia_24. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014202,MedGen:C3809634,OMIM:615481,Orphanet:244. Review status: criteria provided, single submitter.