A: The variant NC_000019.10:g.49390787_49399755del in gene KASH5 is classified as 'Pathogenic' for Spermatogenic_failure_88. Molecular consequence: SO:0001574: splice_acceptor_variant,SO:0001575: splice_donor_variant,SO:0001582: initiator_codon_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0957821,MedGen:C5882706,OMIM:620547. Review status: no assertion criteria provided.