A: The variant NC_000020.11:g.4699524C>T in gene PRNP is classified as 'Likely_pathogenic' for Gerstmann-Straussler-Scheinker_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007656,MedGen:C0017495,OMIM:137440,Orphanet:356. Review status: no assertion criteria provided.