A: The variant NC_000022.11:g.25205359G>A in gene CRYBB3 is classified as 'Pathogenic' for Cataract|Microphthalmia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000518,MONDO:MONDO:0005129,MeSH:D002386,MedGen:C0086543,OMIM:PS116200|Human_Phenotype_Ontology:HP:0000568,Human_Phenotype_Ontology:HP:0007996,MONDO:MONDO:0021129,MedGen:C0026010. Review status: criteria provided, single submitter.