A: The variant NC_000019.10:g.49168309T>A in gene TRPM4 is classified as 'Likely_benign' for Progressive_familial_heart_block_type_IB|Cardiovascular_phenotype. Molecular consequence: SO:0001623: 5_prime_UTR_variant,SO:0001627: intron_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871|MedGen:CN230736. Review status: criteria provided, multiple submitters, no conflicts.