A: The variant NC_000021.9:g.34449623dup in gene KCNE1 is classified as 'Pathogenic' for not_provided|Long_QT_syndrome_5|Jervell_and_Lange-Nielsen_syndrome_2|Cardiovascular_phenotype|Long_QT_syndrome. Molecular consequence: SO:0001587: nonsense. Variant type: Duplication. Disease database links: MedGen:C3661900|MONDO:MONDO:0013372,MedGen:C1867904,OMIM:613695,Orphanet:101016,Orphanet:768|MONDO:MONDO:0012871,MedGen:C2676723,OMIM:612347,Orphanet:768,Orphanet:90647|MedGen:CN230736|MONDO:MONDO:0002442,MeSH:D008133,MedGen:C0023976. Review status: criteria provided, multiple submitters, no conflicts.