A: The variant NC_000022.11:g.35410821C>A in gene MCM5 is classified as 'Uncertain_significance' for not_provided|Meier-Gorlin_syndrome_8. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0033046,MedGen:C4479655,OMIM:617564. Review status: criteria provided, multiple submitters, no conflicts.