A: The variant NC_000022.11:g.20994257T>C in gene LZTR1 is classified as 'Uncertain_significance' for Hereditary_cancer-predisposing_syndrome|Cardiovascular_phenotype. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MedGen:CN230736. Review status: criteria provided, single submitter.