A: The variant NC_000022.11:g.37725788dup in gene TRIOBP is classified as 'Pathogenic' for Autosomal_recessive_nonsyndromic_hearing_loss_28|Rare_genetic_deafness|not_provided. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0012355,MedGen:C1853276,OMIM:609823,Orphanet:90636|MedGen:C5680250,Orphanet:96210|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.