A: The variant NC_000022.11:g.28687924del in gene CHEK2 is classified as 'Uncertain_significance' for Familial_cancer_of_breast|Gastric_cancer. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0016419,MedGen:C0346153,OMIM:114480,Orphanet:227535|Human_Phenotype_Ontology:HP:0012126,MONDO:MONDO:0001056,MeSH:D013274,MedGen:C0024623,OMIM:613659. Review status: criteria provided, single submitter.