A: The variant NC_000021.9:g.32673369_32673372del in gene SYNJ1 is classified as 'Pathogenic' for Early-onset_Parkinson_disease_20|Developmental_and_epileptic_encephalopathy,_53. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0014233,MedGen:C3809824,OMIM:615530,Orphanet:391411|MONDO:MONDO:0033362,MedGen:C4479313,OMIM:617389. Review status: criteria provided, single submitter.