A: The variant NC_000021.9:g.42380140C>T in gene TMPRSS3 is classified as 'Likely_pathogenic' for Rare_genetic_deafness. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C5680250,Orphanet:96210. Review status: criteria provided, single submitter.