A: The variant NC_000021.9:g.31667343G>C in gene SOD1 is classified as 'Uncertain_significance' for Amyotrophic_lateral_sclerosis_type_1|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.