A: The variant NC_000022.11:g.20988009G>A in gene LZTR1 is classified as 'Pathogenic/Likely_pathogenic' for LZTR1-related_schwannomatosis|not_provided|Noonan_syndrome. Molecular consequence: SO:0001574: splice_acceptor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014299,MedGen:C3810283,OMIM:615670,Orphanet:93921|MedGen:C3661900|MONDO:MONDO:0018997,MeSH:D009634,MedGen:C0028326,OMIM:PS163950,Orphanet:648. Review status: criteria provided, multiple submitters, no conflicts.