A: The variant NC_000021.9:g.26021867TGG[8] in gene APP is classified as 'Conflicting_classifications_of_pathogenicity' for APP-related_disorder|Early-onset_autosomal_dominant_Alzheimer_disease|not_provided|Alzheimer_disease|not_specified. Molecular consequence: SO:0001821: inframe_insertion. Variant type: Microsatellite. Disease database links: .|MONDO:MONDO:0015140,MedGen:CN043596,Orphanet:1020|MedGen:C3661900|Human_Phenotype_Ontology:HP:0002511,Human_Phenotype_Ontology:HP:0006878,Human_Phenotype_Ontology:HP:0007213,MONDO:MONDO:0004975,MeSH:D000544,MedGen:C0002395,Orphanet:1020|MedGen:CN169374. Review status: criteria provided, conflicting classifications.