A: The variant NC_000021.9:g.36937076C>A in gene HLCS is classified as 'Likely_benign' for Holocarboxylase_synthetase_deficiency. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009666,MedGen:C0268581,OMIM:253270,Orphanet:79242. Review status: criteria provided, single submitter.