A: The variant NC_000020.11:g.58671287T>C in gene STX16 is classified as 'Uncertain_significance' for Pseudohypoparathyroidism_type_1B|Inborn_genetic_diseases. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011301,MedGen:C1864100,OMIM:603233,Orphanet:94089|MeSH:D030342,MedGen:C0950123. Review status: criteria provided, multiple submitters, no conflicts.