A: The variant NC_000019.10:g.29702917G>C in gene C19orf12 is classified as 'Uncertain_significance' for Hereditary_spastic_paraplegia_43|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014024,MedGen:C2680446,OMIM:615043,Orphanet:320370|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.