A: The variant NC_000019.10:g.49819266A>T in gene MED25 is classified as 'Likely_benign' for not_specified|Charcot-Marie-Tooth_disease_type_2|MED25-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0018993,MedGen:C0270914,Orphanet:64746|.. Review status: criteria provided, multiple submitters, no conflicts.