A: The variant NC_000019.10:g.49168029del in gene TRPM4 is classified as 'Uncertain_significance' for not_provided|Progressive_familial_heart_block_type_IB. Molecular consequence: SO:0001589: frameshift_variant,SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MedGen:C3661900|MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871. Review status: criteria provided, multiple submitters, no conflicts.