A: The variant NC_000023.11:g.12717851_12717854del in gene FRMPD4 is classified as 'Likely_pathogenic' for Neurodevelopmental_delay. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: Human_Phenotype_Ontology:HP:0012758,MedGen:C4022738. Review status: criteria provided, single submitter.