A: The variant NC_000021.9:g.34792488_34792494del in gene RUNX1 is classified as 'Likely_pathogenic' for Hereditary_thrombocytopenia_and_hematologic_cancer_predisposition_syndrome|Myelodysplasia. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0011071,MedGen:CN281654,Orphanet:71290|Human_Phenotype_Ontology:HP:0002863,Human_Phenotype_Ontology:HP:0004832,Human_Phenotype_Ontology:HP:0006730,MedGen:C0026985. Review status: reviewed by expert panel.