A: The variant NC_000020.11:g.4699933C>T in gene PRNP is classified as 'Uncertain_significance' for Vascular_dementia. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0004648,MeSH:D015140,MedGen:C0011269. Review status: no assertion criteria provided.