A: The variant NC_000019.10:g.49865104T>A in gene PNKP is classified as 'Benign' for not_provided|Microcephaly,_seizures,_and_developmental_delay|Ataxia_-_oculomotor_apraxia_type_4|not_specified|Charcot-Marie-Tooth_disease_type_2B2. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0013254,MedGen:C3150667,OMIM:613402,Orphanet:1934|MONDO:MONDO:0014557,MedGen:C4225397,OMIM:616267,Orphanet:459033|MedGen:CN169374|MONDO:MONDO:0011570,MedGen:C1854150,OMIM:605589,Orphanet:101101. Review status: criteria provided, multiple submitters, no conflicts.