A: The variant NC_000019.10:g.36007172del in gene SYNE4 is classified as 'Likely_pathogenic' for Autosomal_recessive_nonsyndromic_hearing_loss_76|Nonsyndromic_genetic_hearing_loss. Molecular consequence: SO:0001589: frameshift_variant,SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0014237,MedGen:C3147083,OMIM:615540,Orphanet:90636|MONDO:MONDO:0019497,MedGen:C5680182,Orphanet:87884. Review status: criteria provided, multiple submitters, no conflicts.