A: The variant NC_000021.9:g.33262691G>A in gene IFNAR2 is classified as 'Uncertain_significance' for Immunodeficiency_45. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014727,MedGen:C4225252,OMIM:616669. Review status: criteria provided, single submitter.