A: The variant NC_000020.11:g.2399579C>T in gene TGM6 is classified as 'Uncertain_significance' for not_specified|Spinocerebellar_ataxia_type_35|Polyneuropathy|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0013485,MedGen:C3888031,OMIM:613908,Orphanet:276193|Human_Phenotype_Ontology:HP:0001271,Human_Phenotype_Ontology:HP:0006941,Human_Phenotype_Ontology:HP:0007287,MONDO:MONDO:0001824,MedGen:C0152025|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.