A: The variant NC_000022.11:g.17209540del in gene ADA2 is classified as 'Pathogenic' for Vasculitis_due_to_ADA2_deficiency|Sneddon_syndrome. Molecular consequence: SO:0001589: frameshift_variant,SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0014306,MedGen:C3887654,OMIM:615688,Orphanet:404553|MONDO:MONDO:0008436,MedGen:C0282492,OMIM:182410,Orphanet:820. Review status: criteria provided, multiple submitters, no conflicts.