A: The variant NC_000020.11:g.63530180G>T in gene PTK6 is classified as 'Uncertain_significance' for Keratoconus. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000563,MONDO:MONDO:0015486,MeSH:D007640,MedGen:C0022578,OMIM:PS148300. Review status: no assertion criteria provided.