A: The variant NC_000021.9:g.31659683G>A in gene SOD1 is classified as 'Uncertain_significance' for Amyotrophic_lateral_sclerosis|Amyotrophic_lateral_sclerosis_type_1. Molecular consequence: SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0007354,MONDO:MONDO:0004976,MedGen:C0002736,Orphanet:803|MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803. Review status: criteria provided, multiple submitters, no conflicts.