A: The variant NC_000020.11:g.25418112C>T in gene GINS1 is classified as 'Conflicting_classifications_of_pathogenicity' for Combined_immunodeficiency_due_to_GINS1_deficiency|not_provided|GINS1-related_disorder. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0044725,MedGen:C5568132,OMIM:617827,Orphanet:505227|MedGen:C3661900|.. Review status: criteria provided, conflicting classifications.