A: The variant NC_000022.11:g.35347137_35347145dup in gene TOM1 is classified as 'Uncertain_significance' for Immunodeficiency_85_and_autoimmunity. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001821: inframe_insertion. Variant type: Duplication. Disease database links: MONDO:MONDO:0030428,MedGen:C5561976,OMIM:619510. Review status: criteria provided, single submitter.