A: The variant NC_000019.10:g.15529722A>G in gene CYP4F22 is classified as 'Likely_pathogenic' for Autosomal_recessive_congenital_ichthyosis_5. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Gene:50992,MONDO:MONDO:0011485,MedGen:C1858133,OMIM:604777,Orphanet:313. Review status: criteria provided, single submitter.