A: The variant NC_000019.10:g.50403104G>A in gene POLD1 is classified as 'Uncertain_significance' for Colorectal_cancer,_susceptibility_to,_10. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0012953,MedGen:C2675481,OMIM:612591,Orphanet:220460. Review status: criteria provided, single submitter.