A: The variant NC_000021.9:g.34880562C>T in gene RUNX1 is classified as 'Likely_pathogenic' for Hereditary_thrombocytopenia_and_hematologic_cancer_predisposition_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0011071,MedGen:CN281654,Orphanet:71290. Review status: reviewed by expert panel.