A: The variant NC_000019.10:g.57235043C>G in gene AURKC is classified as 'Pathogenic' for Infertility_associated_with_multi-tailed_spermatozoa_and_excessive_DNA|Male_infertility_with_spermatogenesis_disorder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009461,MedGen:C0403812,OMIM:243060,Orphanet:137893|MedGen:C5681167,Orphanet:399775. Review status: criteria provided, multiple submitters, no conflicts.