A: The variant NC_000019.10:g.54145938dup in gene CNOT3 is classified as 'Pathogenic/Likely_pathogenic' for Intellectual_developmental_disorder_with_speech_delay,_autism,_and_dysmorphic_facies|Inborn_genetic_diseases|CNOT3-related_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Indel. Disease database links: MONDO:MONDO:0032864,MedGen:C5231456,OMIM:618672|MeSH:D030342,MedGen:C0950123|.. Review status: criteria provided, multiple submitters, no conflicts.