A: The variant NC_000020.11:g.5302255C>T in gene PROKR2 is classified as 'Uncertain_significance' for Hypogonadotropic_hypogonadism_3_with_or_without_anosmia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009482,MedGen:C3550478,OMIM:244200,Orphanet:478. Review status: criteria provided, single submitter.