A: The variant NC_000022.11:g.18078410dup in gene PEX26 is classified as 'Pathogenic' for Peroxisome_biogenesis_disorder|not_provided|Peroxisome_biogenesis_disorder_7B|Peroxisome_biogenesis_disorder_7A_(Zellweger). Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0019234,MedGen:C1832200,OMIM:PS214100,Orphanet:79189|MedGen:C3661900|MONDO:MONDO:0013939,MedGen:C3553951,OMIM:614873,Orphanet:44|MONDO:MONDO:0013938,MedGen:C3888385,OMIM:614872,Orphanet:912. Review status: criteria provided, multiple submitters, no conflicts.