A: The variant NC_000019.10:g.40395740A>G in gene PRX is classified as 'Uncertain_significance' for Charcot-Marie-Tooth_disease,_type_I|Charcot-Marie-Tooth_disease|Distal_spinal_muscular_atrophy. Molecular consequence: SO:0001583: missense_variant,SO:0001624: 3_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0019011,MedGen:C0751036,Orphanet:65753|MONDO:MONDO:0015626,MedGen:C0007959,OMIM:PS118220,Orphanet:166|MONDO:MONDO:0018894,MedGen:C0393541,Orphanet:53739. Review status: no assertion criteria provided.