A: The variant NC_000019.10:g.35746726_35746741del in gene PSENEN is classified as 'Uncertain_significance' for Acne_inversa,_familial,_2. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0013397,MedGen:C3151037,OMIM:613736. Review status: criteria provided, single submitter.