A: The variant NC_000021.9:g.36990257T>C in gene HLCS is classified as 'Benign' for Holocarboxylase_synthetase_deficiency|not_provided. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0009666,MedGen:C0268581,OMIM:253270,Orphanet:79242|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.