A: The variant NC_000022.11:g.28796046C>A in gene XBP1 is classified as 'Uncertain_significance' for Major_affective_disorder_7. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0012881,MedGen:C2700438,OMIM:612371. Review status: criteria provided, single submitter.