A: The variant NC_000019.10:g.45361519C>G in gene ERCC2 is classified as 'Uncertain_significance' for Xeroderma_pigmentosum. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0019600,MedGen:C0043346,Orphanet:910. Review status: criteria provided, single submitter.