A: The variant NC_000022.11:g.17181862_17181868del in gene ADA2 is classified as 'Pathogenic/Likely_pathogenic' for Sneddon_syndrome|Vasculitis_due_to_ADA2_deficiency|not_provided|Autoinflammatory_syndrome. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0008436,MedGen:C0282492,OMIM:182410,Orphanet:820|MONDO:MONDO:0014306,MedGen:C3887654,OMIM:615688,Orphanet:404553|MedGen:C3661900|MONDO:MONDO:0019751,MedGen:C3890737,Orphanet:93665. Review status: criteria provided, multiple submitters, no conflicts.