A: The variant NC_000021.9:g.31663812T>C in gene SOD1 is classified as 'Conflicting_classifications_of_pathogenicity' for Spastic_tetraplegia_and_axial_hypotonia,_progressive|not_provided|Amyotrophic_lateral_sclerosis_type_1. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0032828,MedGen:C5231422,OMIM:618598|MedGen:CN517202|MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803. Review status: criteria provided, conflicting classifications.