A: The variant NC_000021.9:g.31668493T>A in gene SOD1 is classified as 'Pathogenic' for Amyotrophic_lateral_sclerosis_type_1. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803. Review status: no assertion criteria provided.