A: The variant NC_000019.10:g.40705134G>A in gene COQ8B is classified as 'Uncertain_significance' for Focal_segmental_glomerulosclerosis|Nephrotic_syndrome,_type_9. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0000097,Human_Phenotype_Ontology:HP:0004747,MONDO:MONDO:0100313,MedGen:C0017668|MONDO:MONDO:0014257,MedGen:C3809965,OMIM:615573,Orphanet:656. Review status: criteria provided, multiple submitters, no conflicts.