A: The variant NC_000019.10:g.41332123C>T in gene TGFB1 is classified as 'Uncertain_significance' for not_provided|Inflammatory_bowel_disease,_immunodeficiency,_and_encephalopathy. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0032601,MedGen:C4748708,OMIM:618213,Orphanet:565788. Review status: criteria provided, multiple submitters, no conflicts.