A: The variant NC_000021.9:g.43063107_43063108insCCCAGCAAAAGCCCCACCTGGATGATCCACCCCAGTGATCTGCAGAGGGCGCGGCTTCAGGGCTCAAG in gene CBS is classified as 'Benign/Likely_benign' for Classic_homocystinuria|Familial_thoracic_aortic_aneurysm_and_aortic_dissection|not_specified|CBS_POLYMORPHISM|HYPERHOMOCYSTEINEMIA,_THROMBOTIC,_CBS-RELATED|not_provided. Variant type: Insertion. Disease database links: MONDO:MONDO:0009352,MedGen:C0751202,OMIM:236200,Orphanet:394|MONDO:MONDO:0019625,MedGen:C4707243,OMIM:PS607086,Orphanet:91387|MedGen:CN169374|.|MedGen:C3150344|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.