A: The variant NC_000020.11:g.10292909del in gene SNAP25 is classified as 'Likely_pathogenic' for Presynaptic_congenital_myasthenic_syndrome. Molecular consequence: SO:0001589: frameshift_variant,SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MedGen:C0751884,Orphanet:98914. Review status: criteria provided, single submitter.