A: The variant NC_000022.11:g.40366567A>T in gene ADSL is classified as 'Uncertain_significance' for Adenylosuccinate_lyase_deficiency. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001624: 3_prime_UTR_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007068,MedGen:C0268126,OMIM:103050,Orphanet:46. Review status: criteria provided, single submitter.