A: The variant NC_000020.11:g.59300565G>A in gene EDN3 is classified as 'Benign/Likely_benign' for Hirschsprung_Disease,_Dominant|not_provided|not_specified. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN239304|MedGen:C3661900|MedGen:CN169374. Review status: criteria provided, multiple submitters, no conflicts.