A: The variant NC_000022.11:g.40266991C>T in gene TNRC6B is classified as 'Likely_pathogenic' for Global_developmental_delay_with_speech_and_behavioral_abnormalities. Molecular consequence: SO:0001587: nonsense,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030995,MedGen:C5543226,OMIM:619243. Review status: criteria provided, single submitter.