A: The variant NC_000022.11:g.26464127_26464131del in gene HPS4 is classified as 'Likely_pathogenic' for Hermansky-Pudlak_syndrome. Molecular consequence: SO:0001589: frameshift_variant,SO:0001619: non-coding_transcript_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0019312,MedGen:C0079504,OMIM:PS203300,Orphanet:79430. Review status: criteria provided, single submitter.