A: The variant NC_000022.11:g.50526646C>T in gene TYMP is classified as 'Conflicting_classifications_of_pathogenicity' for TYMP-related_disorder|not_provided|Mitochondrial_DNA_depletion_syndrome_1|Mitochondrial_neurogastrointestinal_encephalomyopathy. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: .|MedGen:C3661900|MONDO:MONDO:0011283,MedGen:C4551995,OMIM:603041,Orphanet:298|MONDO:MONDO:0017575,MedGen:C0872218,Orphanet:298. Review status: criteria provided, conflicting classifications.