A: The variant NC_000019.10:g.55661173C>T in gene U2AF2 is classified as 'Likely_pathogenic' for Leukodystrophy. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0002415,Human_Phenotype_Ontology:HP:0006926,Human_Phenotype_Ontology:HP:0007079,MONDO:MONDO:0019046,MedGen:C0023520,OMIM:PS312080,Orphanet:68356. Review status: no assertion criteria provided.