A: The variant NC_000020.11:g.10284751G>T in gene SNAP25 is classified as 'Likely_pathogenic' for Unilateral_Hypotonia|Epilepsy_with_generalized_tonic-clonic_seizures|Focal_epilepsy|Intellectual_disability|Early_infantile_epileptic_encephalopathy_with_suppression_bursts|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D009123,MedGen:C0751330|MONDO:MONDO:0005754,MeSH:D004830,MedGen:C0014549|MONDO:MONDO:0005384,MeSH:D004828,MedGen:C0014547|Human_Phenotype_Ontology:HP:0000730,Human_Phenotype_Ontology:HP:0001249,Human_Phenotype_Ontology:HP:0001267,Human_Phenotype_Ontology:HP:0001286,Human_Phenotype_Ontology:HP:0002122,Human_Phenotype_Ontology:HP:0002192,Human_Phenotype_Ontology:HP:0002316,Human_Phenotype_Ontology:HP:0002382,Human_Phenotype_Ontology:HP:0002386,Human_Phenotype_Ontology:HP:0002402,Human_Phenotype_Ontology:HP:0002458,Human_Phenotype_Ontology:HP:0002482,Human_Phenotype_Ontology:HP:0002499,Human_Phenotype_Ontology:HP:0002543,Human_Phenotype_Ontology:HP:0003767,Human_Phenotype_Ontology:HP:0006833,Human_Phenotype_Ontology:HP:0007154,Human_Phenotype_Ontology:HP:0007176,Human_Phenotype_Ontology:HP:0007180,MONDO:MONDO:0001071,MeSH:D008607,MedGen:C3714756|MONDO:MONDO:0100062,MedGen:C0393706,OMIM:PS308350,Orphanet:1934|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.