A: The variant NC_000019.10:g.38512356del in gene RYR1 is classified as 'Pathogenic' for Central_core_myopathy|RYR1-related_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|MedGen:CN239331. Review status: criteria provided, single submitter.