A: The variant NC_000019.10:g.49861634G>T in gene PNKP is classified as 'Conflicting_classifications_of_pathogenicity' for Developmental_and_epileptic_encephalopathy,_12|Microcephaly,_seizures,_and_developmental_delay|Ataxia_-_oculomotor_apraxia_type_4|not_provided|Inborn_genetic_diseases|not_specified. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013389,MedGen:C3150988,OMIM:613722|MONDO:MONDO:0013254,MedGen:C3150667,OMIM:613402,Orphanet:1934|MONDO:MONDO:0014557,MedGen:C4225397,OMIM:616267,Orphanet:459033|MedGen:C3661900|MeSH:D030342,MedGen:C0950123|MedGen:CN169374. Review status: criteria provided, conflicting classifications.