A: The variant NC_000022.11:g.35386827G>A in gene HMOX1 is classified as 'Conflicting_classifications_of_pathogenicity' for Chronic_obstructive_pulmonary_disease|Heme_oxygenase_1_deficiency|not_provided. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0006510,MONDO:MONDO:0005002,MedGen:C0024117,OMIM:606963|MONDO:MONDO:0013536,MedGen:C1841651,OMIM:614034,Orphanet:562509|MedGen:C3661900. Review status: criteria provided, conflicting classifications.