A: The variant NC_000021.9:g.44533797G>A in gene TSPEAR is classified as 'Pathogenic' for not_provided|Tooth_agenesis,_selective,_10. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0859339,MedGen:C5774277,OMIM:620173. Review status: criteria provided, multiple submitters, no conflicts.