A: The variant NC_000022.11:g.46353755_46353758del in gene TRMU is classified as 'Conflicting_classifications_of_pathogenicity' for Acute_infantile_liver_failure_due_to_synthesis_defect_of_mtDNA-encoded_proteins|not_specified|not_provided|TRMU-related_disorder. Molecular consequence: SO:0001627: intron_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0013111,MedGen:C3278664,OMIM:613070,Orphanet:217371|MedGen:CN169374|MedGen:C3661900|.. Review status: criteria provided, conflicting classifications.