A: The variant NC_000019.10:g.38486104del in gene RYR1 is classified as 'Pathogenic/Likely_pathogenic' for Centronuclear_myopathy|RYR1-related_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0018947,MedGen:C0175709,OMIM:PS160150,Orphanet:595|MedGen:CN239331. Review status: criteria provided, multiple submitters, no conflicts.