A: The variant NC_000019.10:g.50407054G>C in gene POLD1 is classified as 'Likely_benign' for Hereditary_cancer-predisposing_syndrome. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162. Review status: criteria provided, single submitter.