A: The variant NC_000019.10:g.42249293G>A in gene ERF is classified as 'Likely_benign' for TWIST1-related_craniosynostosis. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007399,MedGen:C4551902,OMIM:123100,Orphanet:63440. Review status: criteria provided, single submitter.