A: The variant NC_000021.9:g.32681491T>C in gene SYNJ1 is classified as 'Uncertain_significance' for Developmental_and_epileptic_encephalopathy,_53|Early-onset_Parkinson_disease_20. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0033362,MedGen:C4479313,OMIM:617389|MONDO:MONDO:0014233,MedGen:C3809824,OMIM:615530,Orphanet:391411. Review status: criteria provided, single submitter.