A: The variant NC_000020.11:g.58903707del in gene GNAS is classified as 'Pathogenic' for not_provided|Pseudohypoparathyroidism|Progressive_osseous_heteroplasia. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Deletion. Disease database links: MedGen:C3661900|Human_Phenotype_Ontology:HP:0000852,MONDO:MONDO:0019992,MedGen:C0033806,Orphanet:79443,Orphanet:97593|Human_Phenotype_Ontology:HP:0025027,MONDO:MONDO:0008153,MedGen:C0334041,OMIM:166350,Orphanet:2762. Review status: criteria provided, single submitter.