A: The variant NC_000019.10:g.38467655G>A in gene RYR1 is classified as 'Likely_benign' for not_provided|Centronuclear_myopathy|Malignant_hyperthermia,_susceptibility_to,_1|Malignant_hyperthermia_of_anesthesia|Arthrogryposis_multiplex_congenita|RYR1-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0018947,MedGen:C0175709,OMIM:PS160150,Orphanet:595|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|Human_Phenotype_Ontology:HP:0034733,MONDO:MONDO:0018493,MedGen:C0024591,Orphanet:423|Human_Phenotype_Ontology:HP:0001389,Human_Phenotype_Ontology:HP:0001390,Human_Phenotype_Ontology:HP:0002759,Human_Phenotype_Ontology:HP:0002804,Human_Phenotype_Ontology:HP:0005188,Human_Phenotype_Ontology:HP:0005663,Human_Phenotype_Ontology:HP:0005809,Human_Phenotype_Ontology:HP:0005859,MONDO:MONDO:0015168,MeSH:D001176,MedGen:C5779613,OMIM:PS617468,Orphanet:1037|MedGen:CN239331. Review status: reviewed by expert panel.