A: The variant NC_000019.10:g.45369132C>A in gene ERCC2 is classified as 'Pathogenic' for Xeroderma_pigmentosum,_group_D. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0010212,MedGen:C0268138,OMIM:278730. Review status: no assertion criteria provided.