A: The variant NC_000019.10:g.45364251G>A in gene ERCC2 is classified as 'Pathogenic' for Malignant_tumor_of_urinary_bladder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0001187,MedGen:C0005684,OMIM:109800,Orphanet:157980. Review status: no assertion criteria provided.