A: The variant NC_000019.10:g.49182889G>A in gene TRPM4 is classified as 'Conflicting_classifications_of_pathogenicity' for not_provided|Progressive_familial_heart_block_type_IB|not_specified|Cardiovascular_phenotype|Sudden_cardiac_death. Molecular consequence: SO:0001587: nonsense,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0011474,MedGen:C1970298,OMIM:604559,Orphanet:871|MedGen:CN169374|MedGen:CN230736|EFO:EFO_0004278,Human_Phenotype_Ontology:HP:0001645,Human_Phenotype_Ontology:HP:0005161,MeSH:D016757,MedGen:C0085298. Review status: criteria provided, conflicting classifications.