A: The variant NC_000020.11:g.49254578G>C in gene ZNFX1 is classified as 'Pathogenic' for Immunodeficiency_91_and_hyperinflammation. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0030491,MedGen:C5562073,OMIM:619644. Review status: no assertion criteria provided.