A: The variant NC_000019.10:g.40403714_40403726dup in gene PRX is classified as 'Pathogenic/Likely_pathogenic' for Charcot-Marie-Tooth_disease_type_4|Charcot-Marie-Tooth_disease. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0018995,MedGen:C4082197,Orphanet:64749|MONDO:MONDO:0015626,MedGen:C0007959,OMIM:PS118220,Orphanet:166. Review status: criteria provided, multiple submitters, no conflicts.