A: The variant NC_000022.11:g.50064042_50064043insACCCCCACCCCACAGGCCACTCACCTCCCCGGC in gene MLC1 is classified as 'Benign/Likely_benign' for not_provided|Megalencephalic_leukoencephalopathy_with_subcortical_cysts_1|Megalencephalic_leukoencephalopathy_with_subcortical_cysts. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001821: inframe_insertion. Variant type: Insertion. Disease database links: MedGen:C3661900|MONDO:MONDO:0024555,MedGen:C5779875,OMIM:604004,Orphanet:2478|MONDO:MONDO:0011391,MedGen:C1858854,Orphanet:2478. Review status: criteria provided, multiple submitters, no conflicts.