A: The variant NC_000019.10:g.42370360G>T in gene MEGF8 is classified as 'Likely_pathogenic' for Carpenter_syndrome. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0019012,MedGen:C1275078,OMIM:PS201000,Orphanet:65759. Review status: criteria provided, single submitter.