A: The variant NC_000022.11:g.20997307_20997308del in gene LZTR1 is classified as 'Uncertain_significance' for not_provided|Cardiovascular_phenotype|Hereditary_cancer-predisposing_syndrome. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MedGen:C3661900|MedGen:CN230736|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162. Review status: criteria provided, multiple submitters, no conflicts.