A: The variant NC_000019.10:g.38444211C>T in gene RYR1 is classified as 'Pathogenic|drug_response' for succinylcholine_response_-_Toxicity|sevoflurane_response_-_Toxicity|methoxyflurane_response_-_Toxicity|isoflurane_response_-_Toxicity|halothane_response_-_Toxicity|desflurane_response_-_Toxicity|enflurane_response_-_Toxicity|RYR1-related_disorder|not_provided|Malignant_hyperthermia,_susceptibility_to,_1|Central_core_myopathy|Malignant_hyperthermia_of_anesthesia. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: .|.|.|.|.|.|.|MedGen:CN239331|MedGen:C3661900|MONDO:MONDO:0007783,MedGen:C2930980,OMIM:145600,Orphanet:423|MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|Human_Phenotype_Ontology:HP:0034733,MONDO:MONDO:0018493,MedGen:C0024591,Orphanet:423. Review status: reviewed by expert panel.