A: The variant NC_000019.10:g.49836226C>A in gene MED25 is classified as 'Conflicting_classifications_of_pathogenicity' for Tip-toe_gait|Charcot-Marie-Tooth_disease_type_2|not_provided|Charcot-Marie-Tooth_disease. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0002394,Human_Phenotype_Ontology:HP:0030051,Human_Phenotype_Ontology:HP:0040083,MedGen:C0427144|MONDO:MONDO:0018993,MedGen:C0270914,Orphanet:64746|MedGen:C3661900|MONDO:MONDO:0015626,MedGen:C0007959,OMIM:PS118220,Orphanet:166. Review status: criteria provided, conflicting classifications.