A: The variant NC_000019.10:g.16482685G>A in gene CALR3 is classified as 'Uncertain_significance' for not_specified|Hypertrophic_cardiomyopathy_19. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:CN169374|MONDO:MONDO:0013476,MedGen:CN077603. Review status: criteria provided, multiple submitters, no conflicts.