A: The variant NC_000021.9:g.33345322T>G in gene IFNAR1 is classified as 'Pathogenic/Likely_pathogenic' for not_provided|Immunodeficiency_106,_susceptibility_to_viral_infections. Molecular consequence: SO:0001587: nonsense,SO:0001623: 5_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0030970,MedGen:C5677009,OMIM:619935. Review status: criteria provided, multiple submitters, no conflicts.