A: The variant NC_000019.10:g.35720455_35720456del in gene KMT2B is classified as 'Uncertain_significance' for Castleman-Kojima_disease. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0018702,MedGen:C4552543,Orphanet:457077. Review status: no assertion criteria provided.