A: The variant NC_000021.9:g.36937408GA[4] in gene HLCS is classified as 'Conflicting_classifications_of_pathogenicity' for Holocarboxylase_synthetase_deficiency|not_specified. Molecular consequence: SO:0001627: intron_variant. Variant type: Microsatellite. Disease database links: MONDO:MONDO:0009666,MedGen:C0268581,OMIM:253270,Orphanet:79242|MedGen:CN169374. Review status: criteria provided, conflicting classifications.