A: The variant NC_000019.10:g.16482788dup in gene CALR3 is classified as 'Conflicting_classifications_of_pathogenicity' for Hypertrophic_cardiomyopathy_19|Cardiomyopathy. Molecular consequence: SO:0001574: splice_acceptor_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0013476,MedGen:CN077603|Human_Phenotype_Ontology:HP:0001638,MONDO:MONDO:0004994,MedGen:C0878544,Orphanet:167848. Review status: criteria provided, conflicting classifications.