A: The variant NC_000020.11:g.58910393_58910395dup in gene GNAS is classified as 'Uncertain_significance' for Pseudohypoparathyroidism_type_1B. Molecular consequence: SO:0001624: 3_prime_UTR_variant,SO:0001821: inframe_insertion. Variant type: Duplication. Disease database links: MONDO:MONDO:0011301,MedGen:C1864100,OMIM:603233,Orphanet:94089. Review status: criteria provided, single submitter.