A: The variant NC_000022.11:g.28703533C>T in gene CHEK2 is classified as 'Uncertain_significance' for Malignant_tumor_of_breast. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007254,MedGen:C0006142. Review status: no assertion criteria provided.