A: The variant NC_000021.9:g.31667298G>A in gene SOD1 is classified as 'Pathogenic' for Amyotrophic_lateral_sclerosis_type_1|SOD1-related_disorder. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007103,MedGen:C1862939,OMIM:105400,Orphanet:803|.. Review status: criteria provided, single submitter.