A: The variant NC_000023.11:g.12887637_12887640del in gene TLR7 is classified as 'Pathogenic' for Immunodeficiency_74,_COVID-19-related,_X-linked. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Deletion. Disease database links: MONDO:MONDO:0026767,MedGen:C5435745,OMIM:301051. Review status: no assertion criteria provided.