A: The variant NC_000022.11:g.42631422C>T in gene CYB5R3 is classified as 'Conflicting_classifications_of_pathogenicity' for Central_core_myopathy|Deficiency_of_cytochrome-b5_reductase. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007294,MedGen:C5830701,OMIM:117000,Orphanet:597|MONDO:MONDO:0009606,MedGen:C0268193,OMIM:250800,Orphanet:621. Review status: criteria provided, conflicting classifications.