A: The variant NC_000020.11:g.32796868G>A in gene DNMT3B is classified as 'Uncertain_significance' for Inborn_genetic_diseases|Immunodeficiency-centromeric_instability-facial_anomalies_syndrome_1. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MeSH:D030342,MedGen:C0950123|MONDO:MONDO:0009454,MedGen:C4551557,OMIM:242860,Orphanet:2268. Review status: criteria provided, multiple submitters, no conflicts.