A: The variant NC_000022.11:g.41147866dup in gene EP300 is classified as 'Likely_pathogenic' for Microcephaly|intellectual_deficiency. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: Human_Phenotype_Ontology:HP:0000252,Human_Phenotype_Ontology:HP:0001366,Human_Phenotype_Ontology:HP:0005485,Human_Phenotype_Ontology:HP:0005489,Human_Phenotype_Ontology:HP:0005497,MONDO:MONDO:0001149,MedGen:C4551563|MedGen:CN228659. Review status: no assertion criteria provided.