A: The variant NC_000019.10:g.35730004G>A in gene KMT2B is classified as 'Uncertain_significance' for Poor_motor_coordination|Generalized_dystonia|Dysarthria|Dystonia_28,_childhood-onset. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: Human_Phenotype_Ontology:HP:0002275,MedGen:C1848453|Human_Phenotype_Ontology:HP:0007325,MONDO:MONDO:0000476,MedGen:C1848954,Orphanet:376724|Human_Phenotype_Ontology:HP:0001260,Human_Phenotype_Ontology:HP:0002327,MedGen:C0013362|MONDO:MONDO:0015004,MedGen:C4310633,OMIM:617284,Orphanet:589618. Review status: criteria provided, single submitter.