A: The variant NC_000022.11:g.20997262A>G in gene LZTR1 is classified as 'Uncertain_significance' for LZTR1-related_schwannomatosis|not_provided|LZTR1-related_disorder|Cardiovascular_phenotype|Hereditary_cancer-predisposing_syndrome. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0014299,MedGen:C3810283,OMIM:615670,Orphanet:93921|MedGen:C3661900|.|MedGen:CN230736|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162. Review status: criteria provided, multiple submitters, no conflicts.