A: The variant NC_000022.11:g.20990470C>T in gene LZTR1 is classified as 'Pathogenic/Likely_pathogenic' for Hypertrophic_cardiomyopathy_1|not_provided|Cardiovascular_phenotype|Hereditary_cancer-predisposing_syndrome|LZTR1-related_disorder. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0008647,MedGen:C3495498,OMIM:192600|MedGen:C3661900|MedGen:CN230736|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|.. Review status: criteria provided, multiple submitters, no conflicts.