A: The variant NC_000020.11:g.23048006G>A in gene THBD is classified as 'Uncertain_significance' for Atypical_hemolytic-uremic_syndrome_with_thrombomodulin_anomaly|Thrombomodulin-related_bleeding_disorder|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013044,MedGen:C2752036,OMIM:612926|MONDO:MONDO:0013775,MedGen:C3280976,OMIM:614486,Orphanet:436169|MedGen:C3661900. Review status: criteria provided, multiple submitters, no conflicts.