A: The variant NC_000019.10:g.40395739dup in gene PRX is classified as 'Uncertain_significance' for Charcot-Marie-Tooth_disease,_type_I. Molecular consequence: SO:0001589: frameshift_variant,SO:0001624: 3_prime_UTR_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0019011,MedGen:C0751036,Orphanet:65753. Review status: no assertion criteria provided.