A: The variant NC_000019.10:g.17581404T>C in gene COLGALT1 is classified as 'Uncertain_significance' for Brain_small_vessel_disease_3. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0100105,MedGen:C5193053,OMIM:618360. Review status: criteria provided, single submitter.