A: The variant NC_000019.10:g.49660741G>A in gene IRF3 is classified as 'risk_factor' for Multisystem_inflammatory_syndrome_in_children. Molecular consequence: SO:0001583: missense_variant,SO:0001619: non-coding_transcript_variant,SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C5391534. Review status: no assertion criteria provided.