A: The variant NC_000019.10:g.38580039_38580040inv in gene RYR1 is classified as 'Uncertain_significance' for RYR1-related_disorder|Malignant_hyperthermia_of_anesthesia|not_provided. Molecular consequence: SO:0001583: missense_variant. Variant type: Inversion. Disease database links: MedGen:CN239331|Human_Phenotype_Ontology:HP:0034733,MONDO:MONDO:0018493,MedGen:C0024591,Orphanet:423|MedGen:C3661900. Review status: reviewed by expert panel.