A: The variant NC_000021.9:g.25592807C>T in gene MRPL39 is classified as 'Pathogenic/Likely_pathogenic' for Combined_oxidative_phosphorylation_deficiency_59|Leigh_syndrome. Molecular consequence: SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0957992,MedGen:C5882730,OMIM:620646|MONDO:MONDO:0009723,MedGen:C2931891,OMIM:256000,Orphanet:506. Review status: no assertion criteria provided.