A: The variant NC_000019.10:g.35658644C>G in gene COX6B1 is classified as 'Uncertain_significance' for Mitochondrial_complex_4_deficiency,_nuclear_type_7. Molecular consequence: SO:0001583: missense_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0033637,MedGen:C5436685,OMIM:619051. Review status: criteria provided, single submitter.