A: The variant NC_000022.11:g.31754865G>C in gene DEPDC5 is classified as 'Pathogenic' for Self-limited_epilepsy_with_centrotemporal_spikes. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0007295,MedGen:C0376532,Orphanet:1945. Review status: no assertion criteria provided.