A: The variant NC_000020.11:g.36951530G>C in gene SAMHD1 is classified as 'Likely_benign' for Aicardi-Goutieres_syndrome_5|Aicardi_Goutieres_syndrome|SAMHD1-related_disorder. Molecular consequence: SO:0001819: synonymous_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0013059,MedGen:C2749659,OMIM:612952,Orphanet:51|MONDO:MONDO:0018866,MedGen:C0393591,OMIM:PS225750,Orphanet:51|.. Review status: criteria provided, single submitter.