A: The variant NC_000022.11:g.20987584G>C in gene LZTR1 is classified as 'Likely_pathogenic' for not_provided|Hereditary_cancer-predisposing_syndrome|Cardiovascular_phenotype|Schwannomatosis. Molecular consequence: SO:0001575: splice_donor_variant. Variant type: single_nucleotide_variant. Disease database links: MedGen:C3661900|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,Orphanet:140162|MedGen:CN230736|MONDO:MONDO:0008075,MeSH:C536641,MedGen:C1335929,OMIM:PS162091,Orphanet:93921. Review status: criteria provided, multiple submitters, no conflicts.