A: The variant NC_000022.11:g.37973785C>T in gene SOX10 is classified as 'Uncertain_significance' for PCWH_syndrome|not_provided|Waardenburg_syndrome. Molecular consequence: SO:0001583: missense_variant,SO:0001627: intron_variant. Variant type: single_nucleotide_variant. Disease database links: MONDO:MONDO:0012198,MedGen:C1836727,OMIM:609136,Orphanet:163746|MedGen:C3661900|MONDO:MONDO:0018094,MedGen:C3266898,OMIM:PS193500,Orphanet:3440. Review status: criteria provided, multiple submitters, no conflicts.