A: The variant NC_000019.10:g.50667617_50667623dup in gene SHANK1 is classified as 'Likely_pathogenic' for Neurodevelopmental_disorder. Molecular consequence: SO:0001589: frameshift_variant. Variant type: Duplication. Disease database links: MONDO:MONDO:0700092,MeSH:D065886,MedGen:C1535926. Review status: criteria provided, single submitter.