A: The variant NC_000019.10:g.50688867G>A in gene SHANK1 is classified as 'Pathogenic/Likely_pathogenic' for SHANK1-related_Neurodevelopmental_Disorder|See_cases. Molecular consequence: SO:0001587: nonsense. Variant type: single_nucleotide_variant. Disease database links: .|.. Review status: criteria provided, multiple submitters, no conflicts.