A: The variant NC_000020.11:g.58389262GCCCTC[3] in gene VAPB is classified as 'Uncertain_significance' for Amyotrophic_Lateral_Sclerosis,_Dominant|Spinal_Muscular_Atrophy,_Dominant. Molecular consequence: SO:0001619: non-coding_transcript_variant,SO:0001623: 5_prime_UTR_variant. Variant type: Microsatellite. Disease database links: MedGen:CN239175|MedGen:CN239253. Review status: criteria provided, single submitter.