Drugs and other substances demonstrated to be CYP 3A inhibitors on the basis of clinical studies involving benzodiazepines metabolized similarly to alprazolam or on the basis of in vitro studies with alprazolam or other benzodiazepines (caution is recommended during coadministration with alprazolam): Available data from clinical studies of benzodiazepines other than alprazolam suggest a possible drug interaction with alprazolam for the following: diltiazem, isoniazid, macrolide antibiotics such as erythromycin and clarithromycin, and grapefruit juice.
<alprazolam, int, diltiazem>, <alprazolam, int, isoniazid>, <alprazolam, int, macrolide antibiotics>, <alprazolam, int, erythromycin>, <alprazolam, int, clarithromycin>