Since apraclonidine may reduce pulse and blood pressure, caution in using drugs such as beta-blockers (ophthalmic and systemic), antihypertensives, and cardiac glycosides is advised.
<apraclonidine, advise, beta-blockers>, <apraclonidine, advise, antihypertensives>, <apraclonidine, advise, cardiac glycosides>