If desipramine hydrochloride is to be combined with other psychotropic agents such as tranquilizers or sedative/hypnotics, careful consideration should be given to the pharmacology of the agents employed since the sedative effects of desipramine and benzodiazepines (e.g., chlordiazepoxide or diazepam) are additive.
<desipramine hydrochloride, effect, psychotropic agents>, <desipramine hydrochloride, effect, tranquilizers>, <desipramine hydrochloride, effect, sedative>, <desipramine hydrochloride, effect, hypnotics>, <desipramine, effect, benzodiazepines>, <desipramine, effect, chlordiazepoxide>, <desipramine, effect, diazepam>