Inhibitors of this isoenzyme (e.g., macrolide antibiotics, azole antifungal agents, protease inhibitors, serotonin reuptake inhibitors, amiodarone, cannabinoids, diltiazem, grapefruit juice, nefazadone, norfloxacin, quinine, zafirlukast) should be cautiously coadministered with TIKOSYN as they can potentially increase dofetilide levels.
<macrolide antibiotics, advise, TIKOSYN>, <azole antifungal agents, advise, TIKOSYN>, <protease inhibitors, advise, TIKOSYN>, <serotonin reuptake inhibitors, advise, TIKOSYN>, <amiodarone, advise, TIKOSYN>, <cannabinoids, advise, TIKOSYN>, <diltiazem, advise, TIKOSYN>, <nefazadone, advise, TIKOSYN>, <norfloxacin, advise, TIKOSYN>, <quinine, advise, TIKOSYN>, <zafirlukast, advise, TIKOSYN>