Macrolide Antibiotics (e. g. erythromycin and troleandomycin): Agents of the ergot alkaloid class, of which D.H.E. 45  (dihydroergotamine mesylate) Injection, USP is a member, have been shown to interact with antibiotics of the macrolide class, resulting in increased plasma levels of unchanged alkaloids and peripheral vasoconstriction.
<ergot alkaloid class, mechanism, macrolide class>, <D.H.E. 45, mechanism, macrolide class>, <dihydroergotamine mesylate, mechanism, macrolide class>