Concurrent administration of drugs possessing nephrotoxic (e.g., aminoglycosides, indomethacin), myelotoxic (e.g., cytotoxic chemotherapy), cardiotoxic (e.g., doxorubicin) or hepatotoxic (e.g., methotrexate, asparaginase) effects with PROLEUKIN may increase toxicity in these organ systems.
<aminoglycosides, effect, PROLEUKIN>, <indomethacin, effect, PROLEUKIN>, <cytotoxic, effect, PROLEUKIN>, <doxorubicin, effect, PROLEUKIN>, <methotrexate, effect, PROLEUKIN>, <asparaginase, effect, PROLEUKIN>