In patients receiving another serotonin reuptake inhibitor drug in combination with monoamine oxidase inhibitors (MAOI), there have been reports of serious, sometimes fatal, reactions including hyperthermia, rigidity, myoclonus, autonomic instability with possible rapid fluctuations of vital signs, and mental status changes that include extreme agitation progressing to delirium and coma.
<serotonin reuptake inhibitor drug, effect, monoamine oxidase inhibitors>, <serotonin reuptake inhibitor drug, effect, MAOI>