Concomitant administration of FACTIVE and calcium carbonate, cimetidine, omeprazole, or an estrogen/progesterone oral contraceptive produced minor changes in the pharmacokinetics of gemifloxacin, which were considered to be without clinical significance.
<FACTIVE, mechanism, calcium carbonate>, <FACTIVE, mechanism, cimetidine>, <FACTIVE, mechanism, omeprazole>, <FACTIVE, mechanism, estrogen>, <FACTIVE, mechanism, progesterone>, <FACTIVE, mechanism, contraceptive>