Antifungals: In vitro and/or in vivo data indicate that fluconazole, itraconazole, and oral ketoconazole markedly inhibit the metabolism of cisapride, which can result in an increase in plasma cisapride levels and prolongation of the QT interval on the ECG.
<fluconazole, mechanism, cisapride>, <itraconazole, mechanism, cisapride>, <ketoconazole, mechanism, cisapride>