Although specific studies have not been performed, coadministration with drugs that are mainly metabolized by CYP3A4 (eg, calcium channel blockers, dapsone, disopyramide, quinine, amiodarone, quinidine, warfarin, tacrolimus, cyclosporine, ergot derivatives, pimozide, carbamazepine, fentanyl, alfentanyl, alprazolam, and triazolam) may have elevated plasma concentrations when coadministered with saquinavir;
<calcium channel blockers, mechanism, saquinavir>, <dapsone, mechanism, saquinavir>, <disopyramide, mechanism, saquinavir>, <quinine, mechanism, saquinavir>, <amiodarone, mechanism, saquinavir>, <quinidine, mechanism, saquinavir>, <warfarin, mechanism, saquinavir>, <tacrolimus, mechanism, saquinavir>, <cyclosporine, mechanism, saquinavir>, <ergot derivatives, mechanism, saquinavir>, <pimozide, mechanism, saquinavir>, <carbamazepine, mechanism, saquinavir>, <fentanyl, mechanism, saquinavir>, <alfentanyl, mechanism, saquinavir>, <alprazolam, mechanism, saquinavir>, <triazolam, mechanism, saquinavir>