None
See Gardiac impulse Heart murmurs, 74-76 Heart muscle, effect of degenerations of upon function, 41, 42, 43 Heart, palpitation of, 76 Heart poisons, accelerating, 54 causing irregularities, 70 effect of, on heart action, 4^ 43 slowing, 60 Heart sounds, 71-74 Digitized by Google INDEX 501 Beartt Talvular disease of» 8 arteriosclerotic, lo causes of, 9 combined, 19 compensation in, 33 congenital, of the right side, 18 due to tearing of valves and chordae, 10 extracardial effects of, 34 heart muscle in, 32 left sided, 12-18 pathology of, 9 right sided, 19 syphilitic, 10 Heart weakness, as a cause of asys- tole, 33^ causes of, 3S~38 of primary, 40 effect of, on secretioa of urine, 4i7f 423 functional, 44 of both ventndes, 46 of the left ventricle, 20, 37» 47 of the right ventricle, 37* 48 primary, 40 pulse in, 52, 55 relation of, to angma pec- toris, 78 results of, 46 symptoms of, 49-52 Heart, work of, factors determining, 2 in conservation of accommo- dation, 2-6 increased, of the left ventri- cle, 21-24 of the right ventricle, 18,19 in the pulmonary circula- tion, I in the systemic circulation, 2 in varying demands on circu- lation, 2-6 on exertion, 6, 7, 8, 29, 30 quantitative factors in, 6 relation of, to hypertrophy, 6-8 to subjective sjmtiptoms, 76 Heat regulation, in fever, 391 heat losses in, during rise of temperature, 394 during fall, 396 heat {production in, 392 site of, 399 mechanism of, 400 experimental factors bearing upon, 385- 388 Heat regulation, in health, regulation of, chemical and physi- cal, 389 mechanism of, 388 in obesity, 314* 389 Heat stroke, 390 Hemic murmurs, 75 Hemiplegia, cerebelUr, 450 contractures in, 41^ muscular atrophy m, 479 Hemisystoles, 66 Haemoglobin, changes in bile from hberation of, 261 conversion of, into methaemoglo- bin, 116, 117 by entrance of poisons into red cells, 117* 120 importance of, in respiration, 116, 120, 219, 220 in the anarmias, 102, I03» 105, 107, III in changes of atmospheric pres- sure. 14^ 144 in chlorosis, 107 in polycythemia, 142 solution of, in blood, 103, 116-118; 168 Hsemoglobinaemia, 116 Haemoglobinuria, 116 paroxysmal, 118 Hsemolysins, 118, 168 Haemolysis, by the blood serum, 168, in paroxysmal haemoglobinuria, 118 inhibition of, in the Wassermann reaction, 173 relation of, to bactericidal proc- esses, 168, 169 substances active in, 168, 169 Haemophilia, 136, 375, 376 Hemorrhages, as a cause of anaemia^ 103, 109 of hydraemia, 140 of leucocytosis, 125 into the organs, in leukaemia, 132 in pseudoleukacmia, 132 Hepatic toxaemia, see Liver Hernia, 291 Herpes zoster, 482 Hiccough, 256 High dtitudes, blood in, 143 metabolism in, 218 pulmonary gas interchange and respiratory movements in, 215-218 Hodgkin's disease, 133. See also Pseudoleukaemia Homogentisic acid, in urine, 334 Digitized by Google 502 INDEX Hormones, action of, 304, 37a origin of, 304 tdmuladng effect of, on cellt, i Hunger, 257, 258 gastric contraction waves under- lying. 257 appetite and, 257 HydrsBmia, causes of, 139-141 relation of, to oedema, ga with retention of water, 140, 141 without retention of water, 140 Hydrobilirubin, origin of, 272 Hydrocephalus, chronic, 444 Hydrochloric add of the gastric juice, 236, 237. 240 absence of, 244 action of, upon microorganisms, 154, 245, 246 diminution of, 243-246 increased, 241-^243 in gastric carcinoma, 244-245 Hydrocyanic add poisoning, as a cause of respiratory spasm, 210 effect of, on internal res- piration, 225 Hydronephrosis, mechanism of pro- ducticm of, 418 Hydrophobia, oesophageal spasm in, a33 Hydrops, in acute and dironic nephritis, 91 in cachexias and nervous dis- easeS; 94 Hyperalgesia, 473 Hyperaemia, active, in inflammations, venous, m cardiac stasis, 5Q-52 Hyperaesthesia, nature and causes of, 473 Hyperglycaemia, alimentary, 344 diabetic. 349.350. Immune bodies, 166 diverse, 166, 160 isolation of, 166 normalty in blood, 171 production of, in active immunity, 161, 163 Immune-ferment reaction (Abderhal- den), 186 Immune sera, 162 antibody content of, 176, 177 haemo]>tic action of, 160 Immunity, acquired, 161, 16^ 189 basis of, in infections with organ- isms not forming soluble toxins, 176 epidemiologic and experimental, 156 histo^enic, 194 inherited, 161, 164 Schick's method of determining, 177 relation of, to bacteriddal powers of blood, 164 theories of, 166^ 188 Immunization, active, 161, 178 active-passive, 162, 178 antitoxic 176, 177, 191 duration of, 162, 177 passive, 162, 176, 177 reaction in, 178 Inanition, as a cause of anaemia, ixo as a cause of hydraemia, 140 as predisposing to infections, 159 Digitized by Google INDEX 508 Inanitioii, causes of, 308 complete, 309 formation and excretion of adds in, 329 m fever, 397, 35*, 404 nitrogen excretion m, 318 partial, 309 results of, 309 types of, 308 Incoordination, 453 Indol, toxic effect of, 282 Indophenol rtoction, 122 Infection, and immunity, 151 effect of portal of entry upon character and course of, I57 factors influencing character of, 156 general, of gastro-intestinal origin, 155, 280 of pulmonanr origin, 154 of vaginal origin, 156 manifestations of, in affected organism, 156 protective barriers against; 151-156 resistance of organism to, iSp, 161, 278 significance of epithelial lesions, in acute, 151 Infectious diseases, albuminuria in, anaemia m, 109, 116 bacillus carriers caused by, 191, colkpse in, 86, 87 fever course in, 381 heart complications in, 9, 25, 36^ 39, 41, 4^3 .. haemoglobinaemia in, 117 hydrsemia in, 140 immunitjT after, 164 intoxications in, 157 leucocytosis in, 125 metabolism in long-standing, 319^ 396 proteid destruction in, 319 pulse in, 61, 70 recovery in, 194 saliva in, 230 Inflammations, blood- and lymph- vessel changes in, 91 collateral oedema in, 91 leucocytosis in, 125 purulent exudates in, 91 Inspiratory disturbances, from loss of pulmonary elasticity, 207 in paralysis of vocal cords, 203 in spasm of vocal cords, 200 Inspiratory disturbances in stenosis of upper air passages, 201, 202 Insufficiency, of heart valves, aortic, 12 in hypertroi^hied hearts, 35, 36, 37,. ,38» 39 mitral, 17 muscular, 11 primary, 40 relative. 11 tricuspid, 18 Intermediary bodies. See Ambocep- tors Intermittent claudication, 79, 4^1 Internal secretions, interrelationship of, 572. 37? Intestinal crises of tabes, 286 Intestinal diseases, absorption in, 282 as a cause of anaemia, 109, 113 of digestive disturbances, 282 due to absence of bile, 265 of pancreatic secre- tion, 273, 274 to bacterial processes in bowel, 277 to bacteriaa toxins, 281 to disorders of motility, 284 to protozoa, 282 to secretory disorders, 283 to toxic substances, 276 effect of, on heart, 60 inflammatory, 291 pain in, 297 Intestinal epithelium, behavior of to- ward bacteria and their products, 154.. 277, 278 Intestinal gases, effect of, on intes- tinal movements, 287 in intestinal stenosis, 294 origin of, in health, 296 in diseases of the gastro- intestinal canal, 296 Intestinal movements, antiperistaltic, in ileus, 294 associated with pain, 295, 297 cessation of, in complete sten- osis, 294, 29s decreased, by central nervous influences, 289 by diminished irritability of bowel wall, 289 by muscle spasm, 290 by paralysis of circum- scribed bowel seg- ments, 291 Digitized by Google M4 INDEX Intestinal movements, Increased, by cooling of the skin, 286 by inflamniatOf7 condi- tions, a68 by irritation of abnormal contents, 267 by nervous influences, a86 local nervous mechanism for, normal, of the colon, 265 of the jejunum and ileum, 284 Intestinal musculature, paralysis of, 289, 201 spasm of. 290^ 293, 394. 297 condition of abdominal wan in, 290 Intestinal obstruction, causes of, 291, 292 course of, 295 mechanism of, different types of. 291, 292 results of, 293. 294, 295, 296 Intestinal parasites, as a cause of anaemia, 11^, 114 of eosinophilia, 126 Intestinal secretions, anomalies of, 383, 284 Intestines, spasm of, as a cause of constipation, 290 in obstruction, 293, 294, 297 Intoxication, after operation in echinococcus disease (anaphy- laxis), 185, i85 in diabetes, 358 in fever, 382 in hepatic disease with chronic biliary stasis, 271 in intestinal affections, 276 in nephritis, 429 Invagination (intussusception), mech- anism of, 292 Iron, increase of, in the liver, due to excessive destruction of ery- throcytes, 104, 114, 143 lade of, as a cause of anaemia, no value of, in chlorosis, 108 Irritative phenomena in cerebral anae- mia, 442 Islands of Langerhans in diabetes, 356,360^ Ipolysms, m anaemia, 119 Isoprecipitins^ 172 Itching, in diseases of sensory cuta- neous end-organs, 473 Jaundice, 266 heart acticm in, 60^ 270 haemolytic. 269 in anaemia, 114 Joint disease, as a cause of nrascolar atrophy, 479 nutritional disturbances in, 481 Jugular veins, murmurs in, 89 pulsations in^ in auricula^' fibrillation, 52, 65, 66 in nodal rhythm, 52 in paroxysmal tachycar- dia, 52, 57 negative, 51 positive. 52, 57, 65, 66 Keith-Flack node, 52, 53. 54» 58 Keto-adds, function of in metabolism, 311, 330, 357 Kidneys (see also Renal), atrophy of, due to occlusion of urinary pas- sages, 419 calculi in, and in renal pelvis, 434 function of, 413 ais regulators of composition of blood. 426 h3rpertrophy of, 418 relation of lesions of, to albu- minuria, 422, 423, 424 to glycosuria, 343. 344. 346, 347, 349, 3S0» 35p to haemo^lobinaemia, 121 to uraemia, A2g secretion of, with diminished cir- culation, 416 with increased circulation, 413 Kidneys, inflammation of, albumin- uria in, 423 cardiac dilatation in, 31 cardiac weakness in, ^i, 37, 39 composition of blood in, 100 (anaemia), 139 (hydraemia) oedema in, 91 functional disturbances in, 424, 428 increased blood-pressure and heart hypertrophy in, 25-29^ 81,84 in diabetes, 359 non-coagulabie nitrogen in, 430, 431 phenolsutphonephthalein test in. 431 pulse in, 59 types of, accordinp^ to disturb- ance of function present, ,438 uraemia in, 429 urine in, 414, 417. 423. toxaemia m, 271 urine in, 326, 33^ Liver, role of, glycogemc, 543. 35^ in combating poisons ab- sorbed from intestines, 281 in conversion of carbohy- drates into fats, 312 in diabetes, 352 in fever, 387 in haemoglobinaemia, 116 in urea formation, 333 Local pathology as contrasted with constitutional, 374 Luetin reaction as an index of the constitutional nature of syphilis, 375 Lungs (see also Pulmonary), anti- • septic action of, IS3 brown induration of, 34 diseases of, cardiac dilatation in, 37 cardiac hypertrophy in, 20, 21 cardiac insufficiency in, 37, 47, 48 gaus interchange in the lungs in, 221, 222 distention of, in bronchial asthma, 205, 206 in paroxysmal tachycairdia, 57 oedema of, 95 infections of, 153, 154 loss of elasticity of, 207, See also £mph3rsenia mechanisms for protection of, loij Lymph, bactericidal properties of, 163, 164 circulation of, 89 in central nervous system, 442, 443 composition of, 8^ 94 m inflammations, 91, 94 excessive accumulation of, in lymph spsices, 89 obstruction to flow of, 89, 90, 91 Digitized by Google 006 n^EX Lymphatics, ocdusion of, 91 pressure conditions in, 89, 90 pressure difference between capil- Uries and, 8a 90 Lymph-nodes, leukemic hyperplasia of, 137, 128 genetic significance of, 133 Lymphocytes, in normal blood, lai m pathological blood, 124, 126^ 130 Lymphosarcoma, Kundrat's, I37» 134 Macrocytase, 188 Macrocytosis and microcytosis, 105 Macrophages, 188 Malaria, blood in, 109, 116, 118 (par- oxysmal hxmoglobinuria) fever in, 381 Malnutrition (see also Inanition), effect of previous state of nu- trition upon, 309 effect of exercise upon, 309 factors in, 308, 318 in various diseases, 309 results of, 309 Mediastino-pericardids, heart hyper- trophy in, 24 pulsus paradoxus in, 70 Megaloblasts, 106, 107, in, 113, ii5 Meni^re*s disease, 472 Meningitis, cerebral pressure in, 444 serum therap:^ in, 177 Mercury, absorption of, through the skin, 151 ptyalism and stomatitis f rom» 231 Metabolism, ammonia formation in» 327 course of, with dietetic sufficiency, 310 formation and excretion of purin bases in, 36^ of or^nic acids in, 328-333 of poisons in, and their effect upon heart, 42, 43 in constitutional diseases, 372 in fever, 396 influence of cellular activity upon, 3" of thyroid gland upon, 320 intermediary, 372. of carbohydrates : quantitative disturbances of, 343 of the fats, ^, 3ii~3i8 of the proteids, 318, 325 proteid needs in, 306 Meteorism, 296 Microcytase. 188 Microorganisms, behavior of animal body towards, 151, 159, 161 Biicroorgantsms, cohttral media for, and their importance, 163 oxygen tension of, 163 in affections of the mouth, 229^ 230 of the intestines, 277 of the urinary passages, 433 in the bile, 262, 2^, 264. 268 in nephritis and albuminuria, 424, 427 in valvular lesions, 9 metabolic products of : action of, on heart, 42, 43 numbers of, in fatal infections, 157 obstacles to entrance of, into body, 151 role of, in hydrolytic cleavage of proteids, 326 significance of the normal intes- tinal, 277, 278 of the pathological intestinal, 279, 280, 281 virulence of, 156 Micturition, disturbances of, 459 Milk, antitoxin content of, 171 as a cultural medium for B. ty- phosus, 159 h}ri>otensive action of, 28 Mitral insufficiency, 17 circulatory disturbances due to, 17 combined with other lesions, 16, 19 compensation in^ 17 heart murmurs in, 74, 76 heart sounds in, 72, 73 Mitral stenosis, 15 and insufficiency, 16, 19 compensation in^ 15 heart murmurs m, 75 heart sounds in, 72, 73 relation of, to auricular fibril- lation, 66 Mixed infections, 160 Monosodium urate, in ^out, 366, 3^ in the formation of vesical calculi, 435 Morbus caeruleus, 50 Motility, disturbances of, atactic, 452- 458 choreiform, 466 due to anonialies of sensation, 455 to abnormal imtabihty of the cerebral struct- ures, 467 to contractures, 463 to disturbances of re- flexes, 460 Digitized by Google INDEX 507 Motility, distttrbancet of due to inco- ordinatioii, 452 to muscle disease. 451 from intermittent aandica- tion, 4^1 from lesions of motor tracts, 451 from psychic paralyses, 450 Mountain sickness, diminished oxygen tension in. myotonic reaction m, 452 Myxocdema, thyroid function in, 322 Nephritis. See Kidneys, inflamma- tion of Nerve cells, degeneration of, 476 inaependence of, 475 Nerves, degeneration of, primary, due to poisons and disturbed blood-supply, 451 secondary, 474 Nervous diseases, anaemia in, 109 constipation in, 269 diarrhoea in, 286 cedema in,^ fever in, 385, 386 from gastric dilatation, 255 Nervous system, effect of, on regiua- tion of vascular diameter, 80, 88 functional disorders of, 441 contractures in, 463 general symptoms in, 441 in acidosis, 332 focal symptoms in, 441 motor disturbances in, 449 reflex disturbances in, 458,460 sensory disturbances in, 468 influence of, on the heart- beat, 45 Digitized by Google 508 INDEX Nervous system, infloence of, on tem- perature rc^^ulation, 3S4, 400 on tissue nutrition, 474 influence of diphtheria and tetanus toxins upon, 158, 46a motor system affections of, 476 of the intestines, disturbed motility due to, 269 patholo^ of, in pernicious anaemia, 112 relation of, to diabetes, 347, 357, 361 sympathetic : centres for defecation and urination. Neuralgia of the stomach, 259 Neurasthenia, constipation in, 189 diarrhoea in, a86 heart-beat in, 56, 58^ 61, 69 Neuritis, 475 Neuron theory, 474, 475 Newborn, antitoxin in blood of, 171 jaundice of, 269 ieuco^osis of, 123 renal infarcts in, 366, 435 Nitrogenous equilibrium, 310, 318^ Nitrogen excretion in the urine, in- creased, in disease, 3ia-j2o, 327 (wn- moma) in health, due to diet, 327 influence of carbohydrates upon, 319. yi^ in fever, 397. ?98 ^ ^ ^ Noa mipulses m relation to shock, 87 Nodal rhytl m, 52, 64, 66 Node of Aschoff-Tawara, 5^ 53* 67 of Keith-Flack, » S^ 54. 58 Non-coagulable nitrogen, m the blood, 138 in uraemia, 430, ^i NoscL diseases of, relation of to asthma, 205 Nourishment in relation to albu- minuria, ^i Nursing infant, effect of food upon intestinal flora of, 278 e£Fect of nasal obstruction upon nutrition of, 200 Nutrition, caloric needs of body in, 305 essential substances in mainten- ance of, 304, 305 metabolism of proteids and fats in, qualitative, 324 quantitative, 304, 318 nitrogen equilibrium in, jio undemounshment in, 3G8 Nutritional disturbances, as a resuH of nervous lesions, 474*483 effect of, upon the blood, no upon the heart muscle, 41 from abnormal proteid de- struction, 318-320 due to toxic substances, in hyperthyroidism, 320 from destruction of fats, 319^ 321 from obesity, 313 in anaemia, no in o^stinuria, 336 in diabetes, 357, 358 in fever, 397, 398. 404 in the muscles, 477 of the bones and joints, 481 of the nerves, 474*476 of the sldn, 482 Obesity, 314 associated with anaemia, 315, 316^ 317 cardiac disturbances in, 43, 44, 315 causes of, 3i5"3i8 constitutional, 316, 378 diminished efficiency due to, 314, 315 hereditary influences in, 316 in childhood, 316 oxygen consumption in, 317 relation of, to diabetes, ^57 significance of h3rpophysis in, 318 Ocdusion of the bowel« causes of, 291 course of, 295 (strangulation) Ochronosis, relation of, to alkapto- nuria, 335 Oligemia, 146 Oligocythemia in chlorosis, 107 in nephritis, 109 Ophthalmoplegia as a cause of dizzi- ness, 472 Opsonins, 189 in therapy (Wright), 190 Optic neuritis, in cerebral pressure. See Choked Disk Orientation of the body in space, 471 loss of, dizziness in, 472 due to labjrrinthin disease, 472 due to ocular palsies, 472 mechanism of, 471 Orthotic albuminuria, 421 theories as to cause of, 421 Oxalate calculi, 436 Oxidative processes in fever, 396 Oxyadds, origin of, in intermediary metabolism, 328* 335 Digitized by Google INDEX 509 Ozjrdase reaction, in cells of bone- marrow origin, 122 Oxygen tension, intraalveolar, res- piratory movements in diminished, 215, 216^ 218 03cvgen supply to tissues m, 215-218 of the tissues, in relation to bacterial growth, 163 Pain, causes of, 474 delayed perception of, 468 in angina pectoris, 79 in diseases of the mouth, 229^ 230 in cesophageal disease, 233, 235 in gall-stones, 263, 264 in f^tric disturbances, 243, 259 in mtestinal diseases. 298, 299 in the precordium, 75 in respiratory disturbances, 226 in urinary calculi, 437 on urination, 437 origin of, 474 psychic ^74 ^ ^ Palpitation of the heart, 70 Pancreatic diabetes, 355^57* 360, 361 acidosis in, 330, 358 Pancreatic juice, effect of absence of. upon f^tric and intestinal digestion, 273, 274 effect of penetration of, into abdominal cavity, 275 secretion of, 273 Paralyses, 449"452 Brown-S6quard, 470 cerebral, contractures in, 464 in uraemia, 429 psychic, 450 sensory, 456 (in ataxia), 468 Paraplegia dolorosa, .469. Pararrhythmias, cardiac, 63, 65 due to extrasystolcs, 63 Parathyroid glands, effects of re- moval of, 324 Pareses, motor disturbances in, 450 of the gastric musculature, effects of, 251, 254 . ^. ^ Paraesthesias, due to gastric disorders, 259 due to disease of the peripheral and spinal sensory paths, 473 Paroxysmal tachycardia, si5 methods for ending paroxysm in, 58 pathogenesis of, 58 Pericardial adhesions, as a cause of heart hypertrophy, 24 as a cause of pulsus para- doxus, 70 Periosteal reflexes, 460 Peristaltic hormone, 285 Peristaltic rush, 284 Peritonitis, bradycardia in, 60 constipation in, 289 exudates in, 94 tympany in, 2^ vascular changes in fatal cases of, 86 Pernicious anaemia, 11 1 indication for splenectomy in, "5 Perpetual arrhythmia, 39» 5^, 6$ Pertussis, nature of paroxysms in, 201 Phagocytosis, theory of, 187 Pha^fysis, 165, 188 Phlorhizin glycosuria, acidosis in, 329 causes of, 345, 34^ in starvation, 340 Phosphatic calculi, 430 Phosphaturia, calcium elimination in, 436 Phosphorus poisoning, acidosis in, ''329 bile in, 261 blood in, 145 (polycythemia) hydrolytic cleavage of pro- teids in, 325* ^ Internal respiration in, 225 jaundice in, 268 metabolism in, 325, 326 urine in. 325. 3». 345 ^. Pigmentation, cutaneous, in jaundice, 267, 270 ,.. of the bone-mairrow, hver and spleen in pernicious anaemia, 114 Pineal gland disease, ^3 Pirquet test, as indication of the constitutional nature of tubercu- losis, 375 Plethora, behavior of heart in, 30, 31 genuine, 14S with hyperglobulism and hy- pertension, 146 serous in hydraemia, 141 Pleuritis, exudative, effect of, on gas interchange in lungs, 221 on respiration, 211 on vena cava, 211 obliterative, as a cause of heart hypertrophy, 21 Pneumococcij in endocarditis, $> Pneumonia, bradycardia following, 61 hypertrophy of right ventricle in, 21 interchange of gases in the lungs in, 222 respiration in, 211 Digitized by Google 510 INDEX Pneumothorax, artificia], 21.') behavior of healthy hing and me* diastinum in, 213 circulatory disturbances in, 213 interchange of gases in lungs in, 221 pressure relations in closed and open, 212 Poildlo^osis, in amemia, 105 in chlorosis, 107 in pernicious anaemia, 11 1 in secondary anaemia, 11 1 Poisons, action of, upon the bile, 261 upon the blood, 104, I09» ii3$ 117, 120 upon the heart, 25, 42, 54f ^» 70, 70 (nicotin) upon the intestinal processes* 276 upon metabolism, 319, 320 upon the nervous system, 451, upon respiration, when mixed with inspired air, 218 as a cause of albuminuria, 423 of anaemia, 109, 113 of jaundice, 268 effect of, on proteid decomposi- tion, J19, 320 on respiration, 218, 224, 225 in leucopenia, 126 in methemoglobinaemia, 120 in polycythaemia, 145 resistance of parasites to (diemo- therapy), 191 Poisons, iS7"i59 bacterial, action of, upon the heart muscle, 43 protective forces of the body a^inst, 169 Polyarthritis rheumatica, heart com- plications of, 9, 39, 41 Polychromatophilia, 105, 11 1 Polycythaemia, 142 Polydipsia of psychic origin^ 414, 415 Polyuria, following cathetenzation of ureters, 416 from drinking of excessive fluids, 425 in diabetes insipidus, 4x4 in diabetes mellitus, 359 in epileptic attadcs, 416 in nephritis, 414 in paralysis of renal nerves, 414 Portals of entry, in infections, 151 Posture, effect of, on albuminuria, 421 Potassium dilorate, action of, on red blood-corpuscles, 120 Potassium salts, in their relation to uraemia, 431 Precipitins, 171 importance of, in medico-legal conditions, 173 Pregnancy;, blood in, 123 heart in, 31, 38, 62 urine in, 423 (albuminuria) Premature contractions of the heart, 63 Propionic add in the urine in metabo- lic disorders, 329 Proteids, bacterial, as a cause of fever, 383 Protdds, pathological destruction of : causes of, 318-320 course and products of, 325-327 dangers of, 320 hydration products of,. 325-327 m anaemias, 223, 319 in cardnoma, 319, 320 in diabetes, 358 in fever, 319, 382, 397, 398 in intermediary metabo- lism, 324, 325 ammonia formation in, 327 significance of liver in, 333 (excretion of ammonia) of thyroid substance in, 321 Proteid needs of the body, 306 Protdds, of the blood serum, 137 amount of, 137 occurrence of, in the urine, 422, ^ proteid ratio m, 137 of the food, chemotactic action of, on leucocytes, 124 qualitative metabolism of, 324 quantitative metabolism of, 304, 311, 318 of the urine, source of, 424 total daily excretion of, 425 types and chemistry of, 422, 424, 42s, 4^ 427 produced by bacterial processes in the intestines, 281 significance of, in heat productioi^ ^ 383. ^. , Protozoa, intestinal^ as causes of anaemia, 109 of dysentenr, 282 of fever, 383 Digitized by Google INDEX 511 Psetidocrcmp, 200 Pseadokuksemia (see also Hodgkin's disease), 127, 133 blood changes in, 128, 130, 133 definition of, broad, 133 strict, 137 di£Ferentiation of, from tubercu- lous and sarcomatous processes^ 127, 134 fever and hemorrhages m, 133 lymph glandular hyperplasia tn^ 137, ia8, 133. 135 pathogenesis of, 132, 135 relation of, to leukaemia, 137, 138^ 139, IJ2, 133, 13s types of, 133 Ptomains, toxic symptoms due to m- troduction of, into intestines, 376 Ptyalism, 231 Puberty, albuminuria in, 431 sinus arrhythmia in, 70 Puerperium, bradycardia of, 62 Pulmonary circulation, i condition of, in compensated heart lesions, J4 disorders of and their effect on right heart, 19-31,. 39 in cardiac asthma. 78 in valvular disease, 13, id^ Pulmonary diseases. See Lungs Pulmonary insufficiency, 18 Pulmonary rigidity, in cardiac asthma, 77 Pulmonary stenosis, 18 Pulmonary tuberculosis, gas inter- change in lungs in, 223 heart hypertrophy in, 21 in diabetes, 359 transmission of, by moist droplets, 154 Pulmonic second sound, accentuation of, 7h 72. ^ character of, m aortic msuffi- ciency, 13 in mitral insufficiency, 17 in mitral stenosis, 16 in pulmonary tubercu- losis, 21 reduplication of, 73 Pulse, arterial, acceleration of, 54~S9 behavior of in cardiac asthma, 78 in Cheyne-Stokes breathing, 309 bigeminy of, 64, 66, 67, 69 effect of cerebral influences upon, 55. 59. 60 Pnlse» arterial, effect of reflex in- fluences upon, $6, 60, 70 in aortic instiffiaency. m tricuspid msufficiency, 52 Pulsus, altemans. 66 bigeminus, 64, 66, 67, 69 celer, in aortic insufficiency, 35 irregularis perpetuus, 65 paradoxus, 70 pseudoaltemans, 59 Puncture of the brain, as a cause of fever, 386, 400 of glycosuria, 347 Pupils in Cheyne-Stokes breathing, 209 Purin bodies, 364 as a cause of fever, 384 Pyaemic processes due to mixed mfec- tions, 160 Pyloric reflex, 249 stenosis, 250, 252, 254, 355 Pyogenic organisms, action of, intro- duced subcutaneously and intravenously. 157 as a cause of valvular disease^ 9 Pyrosis, 356 Raynaud's disease, vascular reflexes in, 88 Reaction of degeneration, 477"479 partial, 479 Digitized by Google AIS INDEX Receiptors, 167 (side-chains), 170, iga Rectum, disturbed emptyiiu: of, due to nervous causes, 459^ 400 Reflexes, absence of, 458 disturbances of deep and super- ficial, 460r'^ effect of, on defecation and urina- tion, 459 on the heart-beat, 56, 60^ 70 on respiration, 211 on the secretion of saliva, 33a on vessel tonus, 80 on voluntary movements, 453, 458 increased, 459 in strychnin poisoning and teta- nus, 462 origin of, 460 Regeneration oif red blood-corpusdes, los, "5 Relapsing fever in Hodgkin's disease, 132 Renal diabetes, 3^ Renal function, disturbed, localization of, 427. 430 phenolsulphonephthalein test in, 431 Renal vessels, effect ot diameter of, on the secretion of urine, 413, 416^ 423, 424 Rennin, secretion of, as an index of pepsin secretion, 238 Residual nitrogen, in the blood, 138 in uraemia, 430^ 43i Resistance, against infection, artificial, 161, 162, 17s (typhoid vaccination), 178 natural, 161, 177 (Sdiidc test) bacterial, increased, 191 Respiration, accelerated, 204, 214 automatic regulation of, 202 Cheyne-Stokes phenomenon in, 209 deep, 203, 210^ 214 effect of atmospheric pressure upon, 215, 218 of changes in the alveolar membranes upon, 215 of composition of air upon* 215 of the blood upon, 120^ 219, 220 of stenoses of the air-pas- sages upon, 200-204 of temperature upon, 214 of the pulmonary circulatioa in, 220 Respiration, effect of uniform distri- bution of inspired air in the alveoli upon, 208^ 215 external, 197 importance of olfactory nerves in^ 198, 218 phases of, 202, 203 protective mechanisms for, 197- 200 regulation of the normal, 204, 209 slow, 2Q2, 203, 209 superficial, 204 undisturbed, conditions essential to, 197 Respiration, internal, 223 Respiratory apparatus, methods of re- moving foreign material from, 197- 200 Respiratory centre, alterations in the activity of. Toluntary movements in, 455- 457 Septic diseases, heart complications of, 9 hypinosis in, 136 in mixed infections, 160, 161 Septum defects, cardiac, 18 Serodiagnosis in gonorrhoea, echino- coccus disease and other condi- tions, 174 in syphilis, 173, 174 in typhoid fever, 174, 175 Serum disease, 178, 180^ 185 prevention of, 177 (Schidc test). 185 Serum of the blood (see also Blood Serum), agglutination in, 174 ammoadds in, 139 antitoxins of, 169 bacteriotropins of, 189, 190 cytolytic properties of, 162- 168,169 diminution of proteids in, 139^ If) fat m, 137 ferments and antiferments in, immunological characteristics of, 162-165 inactivation and reactivatioa of, 166 predpitins in, 171 proteids in, 137 watering of, 139^141 Shodc, anaphylactic, 87, 179 surgical, 87 acapnia in, 88 anod-assodation in, 87, 88 venous pressure in, 88 Side^chain theory, 166 Sinus arrhythmias, 70 tachycardias, 58 Skee runners, cardiac hypertrophy in, 8 l^dn, blood-vessels of, in fever, 394* . 395. 396 m normal regulation of body temperature, 388, 389 in stasis dilatation of the heart, ^ nutritional disturbances of, 482 reflexes of, ^ water excretion of, in fever, 395, Sneezing, 198 Sodium chlorid, as a cause of fever, 3&I retention of, as a cause of oedema, 93 Spasm, of the arterial musdes, 79 (angina pectoris), 81, 84, 452 Digitized by Google 5U INDEX Spafm of the oesophagus, 233 (cardio- spasm) of the intestinal musculature, 200 tonic, in occlusion of the bowel, 294f 397 of the pylorus, as a cause of gas- tric dilatation, 252, 253 Spasmophilia in children, ^79 Spinal cord, diseases of, m anaemia, ^ 112 injuries of, and temperature regulation, 385, 3S7, 4fio Spleen, hyperplasia of, in leukaemia and pseudoleukaemia, 127, 128. 130, 133. in polycythaemia, 142 Splenectomy m pernicious anaemia, "5 in haemolytic icterus, 269 Sputum in asthma, 205 Staphylococci, in the etiology of endocarditis, 9 Stasis, cardiac, secretion of urine in, oedema from, 90, 95, 96 (pul- monary oedema) in aortic insufficiency, 13 in decompensated hearts, 34, 47, 48. 49. SO. 51 m paroxysmal tachycardia, 57 venous, manifestations of, 50, .142 (polycythemia) Stenocardia. See Angina pectoris Stenosis, of the bowel, 291-296 of the cardiac orifices, 10, 15, 18 of the oesophagus, 233 of the pylorus, 252, 254 of the respiratory passages, 200, 204 Sternberg's peculiar form of tubercu- losis, 134 Stomach (see also Gastric) affections of, absence of free acid in chronic, 244 as a cause of secondary anae- mia, 109 as a cause of cardiac arrhyth- mia, 70 as a cause of pernicious anae- mia, 113 bradycardia in, 60 paroxysmal tachycardia and, 57 Stomach, atony of, 253 Stomach, dilatation of, 248, 251, 252, 254 acute, 253 atonic, 253 Stomach, dilatation of, bacterial de* composition in, 248, 254 disturbed resorption in, 254 due to anomalies of position and form, 252 fulness and pressure in, 258 in hyperaddity and hyperse- cretion, 243 in pyloric stenosis, 252 nervous S3rmptoms of, 255 without pyloric stenosis, 253 Stomach, emptying of, delayed, 251, 252, 2M effect of, on gastric flora, 2^ of character of gastric contents upon, 250 hurried, 250 pyloric reflex in, 249 through the cardia, 255 Stomach, movements of, 248 hunger contraction waves in, 257 Stomach, secretions of. See Gastric juice Stomatitis, 229 in acute leukaemias, 230 Strangulation of the intestines, 295 Streptococci, in focal infections, 153 in mixed infections, 160, 161 on the heart valves, 9 mutation of, 1^3 Struma, cardiac disturbances due to, 55. 56, 323> 324 (exophthalmic goitre) respiratory disturbances due to, 200 Strychnin poisoning, arterial spasm in, 8ij 84 convulsions in, 462 urine in, 416 Substance sensibilisatrice (Bordet), 166 Subjective disturbances, cardiac, 76^ 77. 78 dyspeptic, 257^-260 intestinal, 297-299 respiratory, 225 urinary, 437 Sugar content, of the blood, 343 after phlorizinization, 345,346 in diabetes, 349 in renal diabetes, 346 in transitory glycosurias, 348 of the urine, in hypergly- caemia, 344. 348* 349 Surgical shock. in disturbances of the reflex arc, 460 in dissociation of brain and reflex centres, 461 Tenesmus, rectal, 299 " vesical, 437 Tetanus, action of spores of, in mixed infections, 160 antitoxin content of blood in, 170, 171 causes of insusceptibility to, 170 convulsions in, 462 Tetanus, hsemolytic action of bacillus of, 159 spread of toxin in, 158^ 462 treatment of, 158 Tetany, relation of, to gastric dilata- tion, 255 Throat affections of, 229, 232 Thrombokinase, in coagulation of blood, 136, 375 Thymus, importance of, in bodily de- velopment, 373 in sudden deaSfi, 373 Thyroid gland (see also Hyperthy- roidism), effect of, upon the heart, 55, S^ 323, 324 upon metabolism, 320 function of, ^i, ^ results of extirpation of, 322 Tobacco, as a cause of angina pec- toris, 79 of arrhythmia, 70 of intermittent claudication* 79 of palpitation, 77 Toluylendiamin, action of, on secre- tion of bile, 261 Tongue, diseases of and disturbances of chewing, 229 paralysis of, as a cause of - „ . dysphagia, 229, 233 lonsils, importance, as portals of en- try for microorganisms, 152 in focal infections, 152, 153 Tonus of the arteries, 26-29, 80, 81 effect of, on blood-pressure, 27- Tophi, 566 Toxic albuminurias, 423 Toxic symptoms. See Intoxication Toxins, bacterial, 157-IJ9 action of blooa serum upon, J^ ... of gastric juice upon, 245 as a cause of albuminuria, 423 of cardiac disease, 0, 43 of haemoglobinaemia, 117 of intestinal disorders, 276 minimum lethal dose of, 157 Tracheal stenoses, effect of, on res- piratory movements, 201 Transfusion in anaemia, dangers of, 119 Transudate formation, due to venous stasis, 51, 90 Trauma, as an etiological factor in infections, 159 Tremor, 466 Digitized by Google 516 INDEX Tricuspid lesions, i8 venous pulse in, 51 Trigeminal nerve, relation of, to trophic disturb^ces in eyes and face, 483 Trvpanosomes, destruction of (chemotherapy), 191 Tubercle bacillus, passage of, through intestinal wall, 155 Tuberculosis, as a cause of anaemia, 109 of cardiac hvpertrophy, 21 of valvular lesions, 9 general bodily chan^ in, 375 proteid destruction m, 319 serodia^jnosis of, 174 Tuberculosis glandular, resemblance of, to pseudoleukaemia, 127, 134 Tumor4» malignant, as a cause of anae* mia, 109, 113 ., , of mcreased proteid de- struction, 319 Tympanites, 296 Typhoid fever, blood in, 126 bradsrcardia following, 61 dissemination of, by bacillus carriers, 191, 270 immuni^r after, 164 local allergy in (Chant»- messe), 186 prophylsu^ic vacdnadoa ia, 175 serodiagnosis of, 174 vaccine and serum then^iy of. 178 Tjrrosin, relation of to alkaptonuria, 335 Ulcer, gastric complications of, 243, 353 etiology of chronic, 242 hyperacidity in, 241 infection in the etiology of, 242 intestinal, effect of, on peristalsis, 268 Urea, elimination of, in fever, 398 significance in functional tests, 428 formation of, 333 in uraemia, 431 Uraemia, 4^9-433 heart action in, 60, 70, 429 hypertension in, 28 in chrcmic infections of renal pelves, 26 Ureteral stenosis, secretion of urine in, 418, 419 Urethral fever, 387 Uric add, excretion of, in the nrine^ 364 in «>ut, 369 m leukaemia, 365 in the new-bom, 366 in the blood, in gout, 368 in calculi, 4^5 origin of, 364, 365 Uric aad infarcts of the new-bom. Urinary bladder, relation of, to renal pelves, 433 Unnairy calculi, 4^ Urinary fermentation, ammoniacal in urinary stagnation in the bladder, 433 Urinary passa^s, formation of cal- cuH m, 434 inflammations of, 433 ocdusion of, 418 painful sensations in, 4^7 Urine, diaracteristics of, in aadosis, . 327,339 in bums, 11^ in diabetes insipidus, 414 in diabetes melutus, 330, 332, in dyspnoea, 223 in fever, ^495. in hsemo^lobinaemia, 118, 121 in hepatic disease, 334 in hyperglycaemia, 344 in infections of the urinary passages, 433. 434. in intestinal obstruction, 293 in jaundice, 267 in pemidous anaemia, 114 in phosphorus poisoning, 345 in renal oedema, ^ in urinary retenticm, 433, 434 Urin^ secretion of, diminished, 416, 417 disturbed, sequelae of, 428 functional disturbances and thdr localization in rda- tion to, 427 increased, 4i3'4i6 influence of drculation in kidnesrs upon, 41J, 416 of composition of tiie blood ui>on, 425 of diuretic substances upon, 426 in disturbances of innerva- tion. 459 of elimination of formed elements (casts), 425 of urinary solids, 430, 426 Digitized by Google INDEX 517 Urine, secretion of^ in disturbances of elimination of water, 419^ 426, 427 in lesions of the secreting membranes, ^19 in obstruction in the kidneys by blocking of the tubules^ 418 outside the kidneys (uni- lateral), 41B mechanism of, 413, 427 Urobilin and urobilinogen in urine and faeces, diagnostic significance of, 272 ^ formation and circulation of, 272 Vaccines^ immunization with, 175, 178 Vagina, mfections in, 156 Vagotonus, in old age, 52 in the puerperium, 62 Vagus, relation of, to arrhythmia, 6ft to asphyxia, ^9, 223 to bradycardia, 59-61, 62 to heart block, 45, (fj to paroxysmal tachycardia, 58 to respiration, 202, 204 Vascular crises, 81, 84 Vascular disease, as a cause of dis- turbances of motility, 451 Vascular spasm, in angina pectoris^ 79 in intermittent claudication, 79,451. Vasomotor paralysis, as a cause of tachycardia, 55 in the infectious diseases, 86 Veins, circulatory disturbances of, due to anomalous heart action, 50, 88 to disorders of the lungs, 116 to pressure upon the great veins, 116 Veins, increased blood-pressure in, 47, 88,90 lymph transudation from, in venous stasis, 90 murmurs in, 89 pulsations in, in cardiac stasis, 51 Venous hum, 89 Vesica] tenesmus, 437 Vocal cords, paralysis of, 203 / spasm of, 200, 201 Volumen pulmonum auctum, effect of, on respiration, 200, 207 Volvulus, 292 Vomiting, 255 Wandering celb, role of, in the pro^ ess of immumty, 187, 193 Wassermann reaction, in syphilis, 174 as an indication of the constitu- tional nature of syphilis, 375 Water, absorption of, through the inn testines, 283, 288 effect of, on the storage of fat^ 312 elimination of, in fever, 388, 395, 405 through the kidneys, 413, 414, 416, 419, 4^ 425, 4^6, 427 retention of, in nephritis, 92, 140^ 141 Water content of the serum, 137 in chlorosis, 107 Whooping cough, 201 Wright's metiiod of vaccination against typhoid fever, 175 Xanthin, in the urine, 364 in urinary calculi, 437 X-rays in leukaemia, 12ft 131 Zymogens. See Enzymes Digitized by Google Digitized by Google INDEX OF DIAGNOSTIC SYMPTOMS AND SIGNS* a- wave, absence of, in jugular trac- ing in auricular fibrillation, 66 Abderhalden reaction, in pregnan<7 and other conditions, 180, 187 Abdominal angina, 259 a-c interval in extrasystolic condi- tions, 64 Accentuation of pulmonic second sound. See Pulmonic second sound, accentuation of. Acetone bodies, occurrence of, in urine, 3asr333 Achylia gastrioL 237, 238 effect ot, on gastric motility, 250 Acidity of gastric juice^ 236, 240 (pure) in relation to bacterial de- composition in conditions of gastric stasis, 246-248 Acidosis, 224, 225 as indicated by an increased am- monia excretion, 327-328, 334 in diabetes mellitus, 358 in children, associated with pro- fuse diarrhoeas, 330 occurrence of, 329^333 Adds, accumulation of, in tbsues, in relation to nephritic oedema (increased hydration capacity of colloids), 93 organic, occurrence of, in nrine, 328-333 Activation of serum, 166 Active contractures, 464 Active immunity, 161, 162 Active-passive immunization, 162 Acute dilatation of the heart, 44*45 in myocardial disease, 36 Adams-Stokes symptom-complex, 68 Adductor spasm of vocal chords, 200^ 201 Agglutination (and agglutinins), 174- 176. 180 Air-hunger in Cheyne-Stokes breadi- ing, 209 in various autointoxications and acidoses, 210 Albumin content, of exudates, 94 of the unne, in pathological proc- esses, 425 under normal conditions, 420 Albuminuria, 420-425, 427 due to constipation, 290 due to extensive destruction of er^rocytes, 121 in diabetes, 359 in paroxysmal hemoglobinuria, 118 in paroxysmal tachycardia, 57 in serum disease, 185 Albumosuria, in fever and other conditions, 326, 427 Alcoholism, in its effect upon resist- ance of individual, 160 Aldehyde reaction, in the recognition of urobilinogen, 273 Alexin. See Complement Alimentary glycosuria, 343-345 relation of, to diabetes melli- tus, 344 Alkaptonuria, 334""33S Allergy. See Anaphylaxis. Amboceptors, 165, 166, 167, 168, 189 action of, according to Ehrlich's side-chain theorv, 166 according to Metchnikoff, 189 effect of cold upon, 118, 160 relation of, to alexins, 165, 166 Amino-acids, in the blood, 138, 139 in the urine, in cystinuria, 336 in gout, leukaemia and infec- tious diseases, 327 in health, 326 variable presence of, in acute yellow atrophy and ^ pihosphorus poisoning, 325, 326 Ammonia, formation and excretion of, 327-328 increased elimination of, in urine, at the expense of urea, in hepatic disease; 333-334 in diabetes, 358 Ammoniacal decomposition of nrine, 433 *rhi8 index is intended as supplementary only to the General Index. As its name Implies, it la^s stress in particular npon diagnostic signs and S3rmptoms, hi this way emphasizmflr again the relationdiip of tiie contents of the volume to cHnical medicine— Bd. 510 Digitized by Google StO INDEX OF DIAGNOSTIC SYMPTOMS AND SIGNS Aiuemia, aplaitic, ii6 associated with obesity, 3x5 chronic forms of, 104-110 due to acute hemorrhage^ IQ3» XQ4 acute asphyxia in, 10$ in Addison's disease, 3^7 local, in Raynaud's disease, 88 •econdaiy, blood picture in, iio^ III causes of, los^ 1x0 Tenous murmurs in, 89 Anaphylaxis, 178-187 m relation to brondiial asthma, 20$ relation of, to fever, 404 relation of, to hay fever, eclamp- sia, etc, 186 Anaphylactic shock. See Shock. Angina pectoris, 799 80 vasomotoria, 80 Anisocytosis, in chlorosis, X07 in chronic anaemias, 105 Ankle oedema, in general statis, 90 in nephritis, 91 in thoracic duct obstruction, 91 Anomalies in form and position of stomach as a cause of dilatation, 25a Antianaphylaxis, i8j Antibodies, action of, widi antigen, 173 content of, in immune sera, 176 effect of high temperatures on formation of, 408 immunization with prepared, 163 increase of, in the body, 162 persistence of, in the blood, 161, 163, 171 source of, 167. 170 Antiferments in the blood, 138 Antiperistalsis, in gastric dilatation and pyloric stenosis, 2^5 inhibition of /colonic, in diarrhoeal conditions, 285 in intestinal obstruction, 294 intestinal, 285 relation of, to regurgitation of food, in cesophageal stenosis^ Antitoxms, action of, 170^ 176 origin of, 162, ITO union of, with oie protdds of the blood, 170 Antitrypsin, in cachexias, 138 Anxiety, sensation of excessive; in cardiac asthma, 78 in disease of tiie coronary artery, 78 Anuria, in renal circulatory disturb- ances of nervous origin, 416 i^ptoms of, 431 Aortic second sound, significance of accentuation of, 72 Apathv, in uraemia, 420 Apex-heat, cardiographic tradngs in ^e examination of, 71 character of, in paroxysmal tachycardia, 57 data derived from study of, 71 Apnoea, in Adams-Stokes syndroms 68 in Cheyne-Stokes breathh^^, 209 Appetite^ increased, in conditions of high atmospheric pressure^ 218 in diabetes insipidusn 414 in relation to secretion of gastric juice, 238 k>ss of, in abnormal fermentative processes in stomach, 248 in fever, 397, 404 in stomatitis, 230 relation of, to hunger, 257, 258 Apraxia, 450 Ameth's dassification of the polynu- dear leucocytes, 121, 122 Arrhythmia, cardiac, associated with bradycardia, 60 causes of, 68, 69 in coronary artery ocdusion, 40 in gastric disorders, 259 in infectious diseases, 41 in jaundice, 270 in neurasthenia, 45 perpetua. See Auricular fibril- lation, sinus, 45 true, 65 Arsenic a^on of, in dilorosis, 109 Arterial pressure. BlcxHi-oorpusdes, white. See Leu- coses. Blooa-cultures, in the diagnosis of infectious diseases, 159 Blood-platdets, increased, in chronic mydoid leukaemia, 127 reduced, in pemidous anaemia, 127 rdation of, to coagulation of blood, 126^ 127 Blood-pressure, arterial, diastolic, 82 diminished, as a cause of oliguria, 416^ 417, 420 associated with increased venous pressure, as a cause of oliguria, 417 in Addison's disease : re- lation to epinephrin defidency, ^^ in bradvcardial condi- tions, 62 in cardiac weakness, 46^ 47 in collapse, 409 in jaundice, 270 in occluskm of coronary artery, 40 in cardiac asthma, 78 increased, as a cause of polyuria, 29^ 413-414 as a cause of brady- cardia, 59 dangers of, 6 following cerebral hemorrhage^ 447 in asphjTxia, 223 in beer drinkers, 30 relation of, to ple- ^ora, 31 in broken cardiac com- pensation, 40 in nephritis. 25 in polycytnaemia hy^ pertonica, 146 in poly^thaemia vera, 142 in relation to arterio- sclerosis and hy- pertrophy of left ventride, 27 to conditions of chronic dysp- noea and hyper- trophy of left ventnde, 24 Digitized by Google 5M INDEX OP DIAGNOSTIC SYMPTOMS AND SIGNS Blood-pressure, increased, in relation to extras^stoles, 63 to retention of ab- normal sub- stances, 439 reduction of, by milk diet, 28 relation of, to viscosity of blood, 26 to apoplexy, 448 in heart weakness, 48 in hsrperthyroidism, 43 in paroxysmal tachycardia*. Cardiac hypertrophy. See Hyper- trophy. Cardiac insufficiency, due to perfora- tion of large brondius into mediastinum, 213 in hyperthyroidism, 43 Cardiac murmurs, 74"76 Cardiac pain. See Pain, cardiac Cardiac weakness, as evidenced by pulsus alterans, 67 cyanosis and dyspnoea in, 50 £minished arterial pressure in, 46, 47 faicreased venous pressure in, 47 oedema in, 51 tachycardia in, 55 transudation into body cav- ities in, 51 venous pulsations in, 51, 5^ venous stasis and swelling of the organs in, 50 Cardialgia, 259 Cardiospasm, 2^, 234, 235 Casts in the urine, 425 Cataract in diabetes, 358 Catheter fever, 387 Central nervous system, degenerative changes in, in leukaemias, 135 Cerebellar ataxia, 458 Cerebral concussion, 447^448 pressure, increased, 443*447. as a cause of bradycardia, 59 relation of, to apoplexv, 448 Cerebrospinal fluid, pressure of, in re- lation to arterial blood-pressure, 443 Charcot-Leyden crysuU, in the blood in myeloid leukaemia, 131 in bronchial asthma, 205 Chemotherapy, I9I"193 Chewing, in relation to secretion of gastric juice, 238 Cheyne-Stokes breathing, 209^ 210 in uraemia, 429 Chill, at onset of acute infections, in- creased heat production during, 392, 394 fai paroxysmal baemoiflobinuria, 118 Choked disk, 444* 445 Choreiform movements, 466 Chylous and diyliform ascites. See Ascites. Circulation, in aortic insufficiency, 35 Circulation, effect of pleural efiFusions and pneumothorax upon, 211 Circulatory conditions in granular kidney, 37 failure, in infectious diseases, 409 symptoms, in asphyxia, 222, 223 day-colored stools, in absence of bile from intestines, 265 Qinical picture of scarlatina, diph* ^eria, etc., as altered by secondary infections, 160^ 161 Qubbed fingers, associated with con- genital hearts, 50 Coagulation of blood, accelerated by ^inephrin discharge, 339 in haemophilia, 136^ 375 retarded, in cases of severe bums, 120 Coagulins, 180 Cocain, injection of, as a cause of fever, ^5 Cold baths, effect of, on excretion of albumin, 421 on the leucocytes, 123, Colic, due to bacterial decompositioiis in bowel, 281 in colica mucosa, 287 in intestinal diseases, 297, 298 in intestinal obstruction,2g4 in spastic constipation, 290 Colica mucosa, 287 Collapse, as a manifestation of the idiosyncrasy of children to cow's milk, 184, 185 in acute pneumothorax, tnetfaod of prevention of, 212 in fever, 393 in infectious diseases, 86 in intestinal obstruction, 29$, 296 in motor insufficiency of stomach, temperature in, 408^ 409 Colloids, relation of, to agglutination, to precipitation, 172 to toxm-antitoxin interac- tion, 170 variations in, in relation to nephritic hydraemia, 141 Color index, in pernicious anaenUa, III, 113 ConuL, in add intoxications, 332-333 in anuric conditions, 431 in heat-stroke, 391 in uraemia, 429 Compensation, cardiac, disturbed, 38 Complement 165, 188 action of, 118, 166, 167, 173^74 Digitized by Google 5M INDEX OF DIAGNOSTIC SYMPTOMS AND SIGNS Complemetit, source of, 165 varieties of, 169 Complement fixation, I73ri74 in conditions other than syphilis, 174 Concentric hypertrophy of the heart, 32 Constipation, 288-391 due to use of saline cathartics, 284 effect of, on output of ethereal sulphates in urine, 282 in abdominal angina, 259 in gastric hyperacidity, 243 in stenosis of bowel, 293, 294 Constitutional diseases, 37^"^ tendency to obesity, 316 Contagiousness, in relation to riru- lence of microorganisms, 157 Contractures, types and causes of, 463-466 Convulsions, 467 as manifestation of idios^crasy of children to cow's milk, 184, 185 •damptic and epileptic, oliguria in, 416 epileptiform, in increased intra- cranial pressure^ 446 in motor insufficiency of stomach, 255 general, as a cause of fever, 386 in asphyxia, 223 in epilepsy, 467^468 in hepatic toxaemias, 271 in jaundice, 270 in strychnin pdsoning and tet- anus, 463-463 in uremia, 4291 432 Coordination, mechanism of, 45^455 Coronary embolism, symptoms of, 40 Cou^h, in bronchial asthma, 205 m gastric disorders, 259 Coughing, action of, in removing for- eign material from respiratory passages, I98r200 as a cause of emphvsema, 207 dangers of diminished, 199 due to entrance of food into nose, 233 undesirability of, 200 Cramps in the stomach, relation of, to gastric spasm, 258 Critical fall of temperature, heat losses in, 396 Curschmann spirals, in bronchial asthma, 205 Cutaneous vasoconstriction, in angina pectoris, 80 Cyanosis, at onset of febrile diseases, 394 m bronchial asthma, 20S in cardiac weakness, 50 in congenital heart disease, 50 in heat-stroke, 391 in respiratory diseases, 224 Cyclic albuminuria in association with paroxysmal hemoglobinuria, 118 Cylindruria, due to constipation, 290 Cystinuria, 336 Cytase. See Complement Cytodiagnosis, 94 Death, due to loss of functioning haemoglobin, in potassiimi chlo- rate poisoning, 129 sudden, in angina pectoris and coronary embolism, 80 relation of thymus to, 373 Decompositions, bacterial, in absence of bile from intestines, 266 Defecation, 290 nervous disturbances of, 459-460 Delayed sensation, in tabes, 408 Delirium, in heat-stroke, 391 in hepatic toxaemias, 271 Dental caries, in diabetes, 359 Diacetic acid, in the urine, 328-333 Diaminuria, associated with cystir nuria, 336 Diarrhoea, 28^-288 as a manifestation of the idiosyn- crasy of children to cow's milk, 184, 185 in diildren, associated with aci- dosis, 330 in intestinal obstmctkMi, 294 in uraemia, 429 Diastolic murmurs, 74, 75 Diastolic pressure, in aortic insuffi- ciency, 14 in relation to blood-flow, 49 Diatiieses and dyscrasias, 372-^^ Digestion, disturbances of, in chloro- sis, 108 eflFcct of, on leucocytes, 123 Digitalis, in relation to increased blood-pressure, 85 Dilatation, of auricles, in auricular fibrUtation, 65 of oesophagus, in oesophageal ste- nosis, 234 acute forms of, 235 of heart, acute, 447-45 cardiac irregularity in, 69 in myocardial disease^ 36 Digitized by Google INDEX OF DIAGNOSTIC SYMPTOMS AND SIGNS £25 Dilatation, of heart, associated witU hypertrophy, 50 compensatory, 12 continual, 50 in heart weakness, 49 in hypertrophied hearts, 50 temporary, 50 of left auricle^ in mitral insof- ficienar, 17 in mitral stenosis, 16 of left ventricle, in aortic insof- fidency, 12 in aortic stenosis, 15 of stasis, in cardiac weakness, 49 of stomach, associated with con- stipation, vomiting and hy- persecretion, 289 acute, 253 atonic, 253. 254 causes and effects of, a5i"355 due to hypersecretion, 243 in cases of abnormal gastric fermentation, 248 Diminution in size of heart following exertion, 30 Diphtheroid bacillus in Hodgkms disease, 134 Distention, of lungs, acute, in parox- ysmal tachycardia, 57 in bronchial asthma, 205, 206 of stomadi, in cases of abnormal fermentative processes, 248 Direct symptoms of cerebral press- ure, 44JS Dislocation of mediastinum, in pleu- ral effusions and pneumothorax, 211, 212. 213 Diurnal variations of fever, 381 Dizziness, 473. See also Vertigo, in relation to cerebral anasmia, 44a Dysphagia, 2337336 I^pnoea, cardiac, 77, fS paroxysmal (cardiac asth- ma), symptoms of, 78 periodic 77 sensation of oppression and anxiet:^ in, 77 chronic, in its relation to hi^ blood-pressure and hypertrophy of left ventricle, 24 definition of, 225, 226 due to tympanites, 297 expiratorv, due to membranes and polyps below glottis, 203 explanation of, in emphysema, 206 in aortic insufficiency, 13 in bradycardia! conditions, 6i Psrspnoea, in bronchial asthma, 204, 205, 206 in cardiac decompensation, ex- planation of, 215 in cardiac weakness, 50 in Cheyne-Stokes breathing, 209 in hysteria, 211 in membranes and polyps above glottis, 203 in mountain sickness, 316 in pemidotts anaemia, 112 inspiratory, in paralyses of pos- terior crico-arytenoid muscles, 203 in stout individuals, 315 in weakness of the ventricles, 48 CEdema, 89796 in cardiac weakness, 51 in paroxysmal tachycardia, 57 in relation to retention of abnor- mal substances, 429 of skin, in cachexia, 378 Electrocardiographic studies, applica- tion of, to anaphylactic shodc,87 in auricular fibrillation, 66 in conditions of over-exer- tion, 30 in pulsus alteransj 66, 67 Emaciation, due to administration of iodin compounds, 322 in chlorosis, 107 in conditions of high atmospheric pressure, 218 in fever, 40^ in thyroid disease, 320 Embolism of coronary artery, in rda« tion to heart wealoiess, 40 Embryocardia, in. 