None
194, 196 (footnote), 216 (footnote) Cata. polyneuritis in, 119, 207 Celiac diwaae doe to lack of vitamiDS. 172 Central nenroua system, effect of lack of vitamins on, 171, 172 Cereal diet, xerophthalmia resulting from restriction to. 235 CePBttl germ, content of B in, 78, 79 Cereal grains, dry, content of C in, 83 Cereal grains, relative values of proteins in, 55 Cereals, sprouted, antiscorbutic value of, 232 CerMls. sprouted, thermostability of C in, 100 Cerealfl, vitamin index of, 132 Cerebellar symptoms in avian poly- Oiard. eoAtcBt of ^ in, 72 CWrd, limiiMliliili^ of j1 in, 03 fV—i, fitamm eontant of. 302 TVmii«I | «o|wr ti a» of B. 130, 131 Chawed stnKtvre of vitunios. 128. 129 CkscksBi. cDmimBUa with cuotinoid- frae Aet for. 70 B M tiili re requiremetils of, 21 , ^ynliieais of ritamina by. 167, 221 ChiAena^ vitality influenced by vitamin eantCBt cf moiber's diet, 88 Otifkpnw, xenphllialmia in. 235 Oifldmi's diwaiwa, relation to vitamin dtficieory, 172, 292. 310, tl OiinM*, beHberi among. 201 Chlorine metabolism in acunry. 228 ClUorafann, solubility of ^ in. 111 Chloro fo r m , solubility of fi in from horaeflesfa in. 117 Chlorosia, deficiency of vitamins a factor in. 174 Cbooolate y^st. 148 Cboof^te, vitamin. 148 Cholesterol, 7, 8, 15, 113 Choline, 122, 123, 183 Choline-likc bases from rice, anti- neuritic propcrtiea of, 127 Chronic polyneuritis, 208 Cider, antiscorbutic value of, S3, ^9, 230 Cinchonine, antineuritic properties of. 128 Circulatory disturbances in latent scurvy, 218, 219 Circulatory disturbances, relation of vitamins to, 309 Citnuinic acid, 128 Citric acid, effect on thermostability of C, 100, 134, 135 Citrus juices, minimum anUscorbutic doec for guinea-pig, 232 Clover, content of A in, 72, 73, 136 Clover, content of B in, 81 Clover, dried, as source of A, 137 Cochlearia officinalis, 232 Cod liver oil, effect on calcification of bonc«, 17?, 195 Cod liver oil, remedial effect in ricketa, 194, 195, 198, 199 Cod liver oil, thermostability of >1 in. 00 Cod liver oil, vitamin content of . 68, 69 SUBJECT INDEX 371 ^| Colon, relation of ritamm deSciency to Cooking of vegetables, effect of acids and ^^H inflammation of, 311 alkalis in, 134, 135 ^^1 Colon, eflfect of lack of B in, 173 Com, biological value of protein of, 258 ^^^| Colostrum, content of .4 in, 74 Com embryo, antineuritic properties of, ^^^H Commercial vitamin preparations, 147, ^^H 148, 149 Com endosperm, antineuritic value of, ^^^| Complex of A existing in plant tissues. ^^M 111 Cora gluten, lactalbumin as supplement ^^^| Compound lard, 114 to, 268 ^^H Concentration of B from animal tissue, Com in antiscorbutic ration, 83 ^^^| method of VopRtJin, 138 Com, kaffir, in antitucorbutic ration, 83 ^^^| Concentration of B, method of Funk, Com meal, ether extraction of A from, ^^^H 139 ^^M Concentration of B, method of Gams, Com meal, nutritive deficiency of, 47 ^^^| 140, 141 Com, milk-producing value of, 265 ^^^H Concen tra tion of B from pancreatic Com oil, rclati(m between color and ^^^| extract, 141, 142 content of v4, 76 ^^^| Concentration of B, method of Fraenkel Com protein, nutritive value of, 47, 258 ^^^| and Schwars, 142 Com, variation in craitent of A in, 75 ^^^| Concentration of B from wheat Berm, Com, vitamin index of, 80 ^^^| 142, 143 Com, white, content of A in, 75 ^^^H Concentration of B, method of Boeshard Com, yellow, thermostability of A in, 92 ^^^H and Hefti, 137, 138 Com, yellow, content of A in, 75 ^^^H Concentration of C from fruit juices, Correlation of vitamin content with ^^^| 143 and S function, 74, 75 ^^^| Concentratiou of C from fruit juices, Cortex, adrenal* degenerative changes ^^^| McClendon's method, 146, 147 caused by lack of C, 177 ^^H Condensed milk, antiscortubic vnlue of, Cottonseed oil, relation between color ^^^| 104, 165 (footnote) and content of A, 76 ^^^| Condensed milk in infant feeding, 295 Cotton seed, toxicity of, 32 ^^^H Condensed milk, nutritive value of, 282, Cows, effect of ration on vitamin content ^^^| 283, 286 of milk, 165 ^^M Condiments, 6 Cows, feeding experiments with, 274, 275 ^^^| Congestion, intestinal, relation of vita- Creatinine in milk, 262 ^^^| min deficiency to, 173, 311 Crcatinuria on diets deficient in B, 180 ^^^| Conjunctivitis, 234 and ff (See also Crisco in basal diet, 237 ^^^| Xerophthalmia) Critirt.'<m uf vitamin research, 'M ^^^H Conjunctivitis, effect of yeast on, 311 Crystalline preparations of antineuritio ^^^H Constipation, efre<*t of yeast cm, 311 substances, 121 and ff ^^^| Constipation, relation of scurvy to, CururbitouH vegetables, thermostability ^^^H 226, 227 of A in, 92 ^^H Constipation, relation of vitamins to, Curd of mUk, 263 ^^B 309 Curve, time, of destruction of Cin tomato ^^^| Consumption of food cm deficient diets, juice, 102 ^^H 175 "C-Y/' 148 ^^M Control diets, 22 Cyclic compounds, influence of vitamins ^^^| Convicts, feeding experimenls to produce in syntheses of, 187 ^^^| beriberi in, 303, 204 "Cyclokeiasee," 187 ^^M Cooked food, necessary data in experi- C^'stine, xi, 54 ^^^| ments with, S9 Cystine as supplement to caAcin, 54, 2€6 ^^^| Cooking, effect on antiscorbutic value Cystine as supplement to lactalbumin, ^^^H of food, 232 ^^M Cooking, effect on antiscorbutic value ^^^M of potatoes. ^^1 Dextrin in bnsnl diets, 57 McClendon's, 144, 145, 146 ^H Dialysis of B, 117, 134 Drying, destruction of C in beef by, 109 ^H Dialysis of C, 132, 134 Drying destruction of C in cabbage bv, ^^M Diet, antineuritic, 215 100 ^^M Diet influencing vitamin content of milk, Drying, destruction of C in potatoes by, ^H 74, 82 107 ^^M Diet, modified, for prevention of beri- Drying, effect on antiscorbutic value of ^^M beri in Japanese navy, 203 foods, 90, 105 and ff ^^M Diet, neurilic, used at Kut-el-Amara, 206 Dn-ing, effect on antiscorbutic properliea ^^M Diet, nouritic, used In Japanese navy, of food, 232 ^m 203 Dr>'ing, effect on antiscorbutic value of ^^M Diet, neuritic, used in Javanese prisons, tomatoes, 108 ^M 204 Drying, effect on antiscorbutic value of ^H Diet, neuritio, used in lunatic asylum. vegetables, 106 ^m ^^ Dr>>ing, effect on content of ^ in foods. ^^M Diet, neuriUo, used in Philippines, 205 93 ^H Diet, sterilized, effect on human beings, Drying, effect on content of B in foods, ^M 203, 204 94, 96 ^V DietA, beriberi-pToducLng, 203, 204, 205, Drying, effect on vitamin content of ' 206 foods. 307, 308 Diets, control, 22 Drying of fruit juices, commercial proc- Diets deficient in fat, effect on children ess for, 109 of, 235, 236 Drying of milk, commercial prooeaaes Diets in rachitic families, 195 for, 146, 147, 286, 287 Diets, MeUanby's rachitic, 196, 197, 198 Drying of vegetables, optimum temr Digestion, effect of lack of B on, 171, peratures for, 107 172, 173 Duodenal ulcer, effect of yeast on, 311 Digestion of foodstuffs, x Duodenitis in beriberi, 206 Digestive glands, function of vitamitks in stimulating, 184 and ff £k!iemas, effect of yeast on, 31 1 1 Dilation, intestinal, relation of vitamin Kdestin, bacterial growth-stimulant in. ^^^ deficiency to, 311 160 ^^B Diphtheria, relation of vitamin deficiency JBdestin, biologic value of, 266 ^m to, 310 Edestin, retention of B by, 130 ^^L^^ Dogs, feeding e3q>eriments with, 97, 110, Eel fat as cure for xerophthalmia, 235 SUBJECT INDEX 373 Efficiency of aninml body, ix Eggfl, antiscorbutic value of, 86 Eggs, aDtlDcuritio value of, 82 Eggs aa supplement to wheat flour, 55 Eggs, earottnoid free, as source of ^4, 77 Eggs, content of B in, 82 Eggs, dried, a« source of B, 81 EggR, variation in antiscorisutic value due to diet of hens, 88 Eggs, vitamin content of, 302 Egg-yolk, antineuritic value of, 83, 215 Egg-yolk, antineuritic and growth-pro- moting power compared, 152 Egg-yolk an ingredient of experimental dieta, 8, 12 Egg-yolk fat, vitamin content of, 68 ^gg-yolk, growth-promoting value of, 3, 12, 15 Egg-yolk, ether extraction of A from, HI Egg-yolk, ether extraction of B from, 1 16 Egg-yolk, thermofitahiiity of A in, 90 Elizabeth, N.J., outbreak of beriberi at, 206 Emaciation, lack of ^4 a cause of, 167, 170 Emanation, radium, effect on B in yeaat, 98 Embr>'o, animal, content of B in, 182 Embryo, com, content of B in, 78 Embryo, wheat, content of B in, 78 Endocrine function, relation of vitamins to (See Internal secretion) Endocrine glands, content of vitamin B in, 82, 185 Endocrine glands, relation of vitamin deficiency to disturbance of, 171| 172, 185, 186, 187, 311 Endoapcnn, com, lack of B in, 150 Endosperm, distribution of vitamin B within, 791 Endosperm, grain, lack of B in, 78, 150 Endosperm of aeeds, composition of, 75 Endosperm, wheat, as source of B^ 78, 150 Energy of body, xl Energ>' value of food, xi Energy of muscular work, xii Energy requirement, xiii "Enriched" milk in infant feeding, 296 Ensiling, effect on content of vl in fodder, 92 Ezuymes, 185 En^rme action a factor in the destruction of antiscorbutic power of orange juice, 109 Enaymes, effect on thermostability of antuoorbutic vitamin, 107, 108, 109 Erythema, effect of yeast on, 311 Ether, solubility of A in, 111, 112, 136 Elher, solubility of B in, 116, 117 Ethyl acetate, solubility of B from horse-flesh in, 117 Evaporated milk in infant feeding, 295 Eva]>orated milk, nutritive value of, 282, 283, 286 Ewe milk fat aa food for rats, 77 Ewe milk fat as source of .4, 115 Ewe milk fat, carotin content of, 77, 115 Exercise, beneficial effects in ricketa, 196, 198 Exogenous hormones, 180 £Ixpcrimental animals, advantage of small, 18 Experimental animals, considerations governing selection of, 44 Experimental animals, treatment of, 21, 22, 23, 24, 45 Extraction of A from plant tissues, 111, 112, 136 Extraction of A from plant tissues by solvents, factors influencing, 111, 112 Extraction of A from plant tissues, McClendon's method for, 137 Extraction of A from saponified butter fat, 113 Extraction of B, 137 and ff Extracta of vitamins aa supplement to diet, 207, 302, 308 Eye diseases due to lack of A (See Xerophthalmia) Fat content of milk, variation in, 261, 262 Fat deficiency a factor in ricketa, 194, 196, (footnote), 199 Fat free diets, experiments with, 163, 179, 194, 196 (footnote), 199, 236, 237 Fat' metabolism, relation of vitamins to, 173, 179, 180 Fatrsoluble vitamin, 4 Fa^solubility of B, 117 Fat starvation in children, 235, 236 Fats, ix, X Fats, absorption of, x Fata, antirachitic value of, 194, 106, 197, 198 Fats, digestion of, x Fats, dispensability in diet, 179, 235, 236,237 Fats, function in diet, 236, 237 Fata, hydrogonatcd, 301 Fata, vegetable, content of A in, 71 Fata, Tegetabk, in infant feeding, 296 374 SUBJECT IM)EX Fats, vegcUhle. need in oleomargarine, 301 Ftttty acids, x Fatty infiltration due to lack of B, 173 Feces from oat diet, ohararler of, 4fl Ferric hydroxide, colloidal, as absorbent of B, US Fibrin, bacterial growth'Stiinulflnt in, 100 Fiah, biological value of protein of, 258 Fish, content of A in, 71 Fish, content of B in, 82 Fish oils, vitamin content of, 68 "F'lftsh" pasteurization, 277, 282 Flaxseed, content of A in, 73 Flaxseed protein, biological value of, fil, 52 Flavoring extracts, function in diet, 175 Flocculcnt precipitates as ab0orbcnts of B, 118 Flour, bolted, a cause of beriberi, 306 Flour milling, removal of vitamin in, 79 Fkmr, soya bean and wheat mixtures, 77 Flour, white, deficiency of, 70, 214 Folin-Macallum reagent, 131 FoUiculitiR, effect of yeast on, 311 Food consumption on deficient diets, 175 Food consumption, effect of milk on, 10 (See alflo Food intake) Food intjike, methods of determining, 22, 24, 33, 34 Food intake, necessity for data conoem- ing, 34 Food preservation, effect on antiscoi^ butJR value, 99 Foodstuffs, ix, X Fourth vitamin, evidence for, 150 and ff Fowls, feeding experiments with, 13, 25, 76. 88, 143 (footnote), ISO. 183, 203, 205, 208, 216 (footnote), 235. 254 Fowls, vitamin A requirement of, 76 Fractionation of acetic acid solution of B by alcohol, 115, 116, 119 Fro»en meat, antineuritic value of, 97 Frozen meat, antiscorbutic value of, 110 Fruit juices, commercial drying of, 100, 147 Fruit juices, concentration of C from, 144 and ff Fruit juices, dried, stability of C in, 144 and ff Fruits as antiscorbutics, S3 Fniite, content of A in, 74 Fruits, content of B in, 82 Fuller's eartb, activated, 141, 154 Fuller's earth, activated, antineuritic and growth-promoting power com- pared, 154 Fuller's earth an absorbent of viUunins, 113, 117, US Function of organs eorrelated with vitamin content, 74, 75 Ftmction, physiological, of vitamins, Iftl and ff Functioning cells, oorrelation of vitamin content with, 181, 182 Furunculoeis, effect of yeast on, 311 Gastric disttirbanoe in beriberi, 206 Gastric glands, stimulation by vitamins, 184 Gastric insufficiency, relation of vitamins to, 172 Gastrin, 186 Gastro-inteetinal catarrh, effect of yeast on, 311 Gastro-intestinal disorders, lack of vita* mins a cause of, 172, 173 Gastro-inlestinal tract, effect of lack of vitamins on, 173 Gelatin as supplement to oat kernel* 49 Gelatin, bacterial growtb^etimtilant in, 160 Georgia velvet bean, content of A in, 73, 74 (footnote) Georgia velvet bean, thermostability of A in, 92 Germ (See also Embryo) Germ, commercial wheat, as source of antineuritic, 215 Germ of seeds, composition of, 75 Germ, wheat, growth promoting and antineuritic power compared, 162 Germinating lentils, antiscorbutic value of, 84 Germinating peas, antiscorbutic value of, 84 Germinating seeds, antiscorbutic value of, 84 Germination of seeds for use as anti- scorbutics, 84 Glands, adrenal, effect of lack of C on, 177 Glands, intestinal, relation of vitamin deficiency to depressed activity of, 311 Glands, lymph, content of B in, 82 Glands of internal secretion (See Endo- crine glands) Glands, stimulation by vitaxnins, 184, 185, 186. 187 Glands, swollen, effect of yeast en, 311 SUBJECT INDEX 375 GUnduUr adipose tiseuc, effect of vita- min deficiency on, 180 Gt&ndular organs, value in the diet, 903 Glandular organs, vitamin content of, 303 Glucose, stimulating effect on yeast growth. 41, 42 Glucosides, hormones produced from, 180 Gluten feed, milk-producing value of, Gluten feed, nutritive deficiency of, 47 Glyoxalaee content of liver in poly- neuritis, 187 GoaU, feeding experiments with, 274, 276 GonococcuB, 317 Grains, distillera, milk-producing value of, 265 Grains, thermostability of ^4 in, 02 Grains, thermostability of B in, 96 Grape-fruit, content of A in, 74 Grape-fruit, content of B in, 82 Grape-fruit juice, dried, antiscorbutic value of, 109 Grap<vjuice, antiscorbutic value of, 83 Grape-juice, content of £ in, 82 Grasflcc) as souroc of A, 72, 73. 136, 137 Grasseii as source of B, 81 Gravimetric yeast test for B, 37 Grip infection, relation of vitamin de- ficiency to, 310 Ground nut (Sec Peanut) Growth and appetite, relation between, 175, 176 Growth, effect of A on, 167, 168 Growth, effect of B on, 175 Growth inhibition on diet containing vitamin, 152 Growth promoting and antineuritic factors, comparison of thermostability of, IM and ff Growth-promuting as distinct from anti- neuritic factor, 150 and ff Growth -promoting as distinct from anti- neuritic factor, distribution of, 150 Growth-promoting factor, properties of, 153 and ff Growth promoting factor, aeparation from antineuritic, 153, 154, ISO, 160 Growth-promoting factor from yeast, separation of, 152, 153 Growth-promoting function of A^ 168 Growth-promoting value of brewer's yeftst, 14 Growth -promoting value of butter-fat, 3, 12 Growth -promoting value of egg-yolk, 3, 12. 15 Growth-promoting value of meat, 197 Growth-promoting value of milk, 3, 9, 10, 11 Growth-promoting value of protein, numerical expression for, 55 Growth stimiiliition in children due to administration of vitamin, 290, 297 Guinea-pig, requirements for C, 166, 232, 233 Guinea-pigs, feeding experiments with, 18, 19, 25, 33, 83, 84, 85, 86. 99, 100, 101, 102, (footnote), la*?, 101, 105, 133, 147, 166, 178, 269, 271, 277, 284, 290 Guinea-pigs, symptoms of scurvy in, 221, 222, 223 Guinea-pig test for presence of C, value of, 232, 233 Hay, antiscorbutic value of, 104, 105, 290 Hay from immature grasses, content of B in, 81 Heart action, effect of vitamin extract on, 183 Heart, effect of lack of A on, 169 He^rt, effect of lack of B on, 171, 173 Heart muscle, effect of lack of B on, 173 Heart, effect of lack of C on, 228 (foot- note) Heart, ox, antineuritic and growth- promoting power compared, 152 Heart, ox, bacterial growth-etimulant in, 160 Heart, pig, dried, content of A in, 91, 92 Heart protein, content of B in. 82 Heat, factors influencing destruction of B by, 120 Heat, factors influencing destruction of C by. 107, 10«. 109 Heat, stability of A to, 90. 91 Heat, stability of B toward, 94, 119, 120, 155 and ff Heat, stobility of C to, 99, 100, 107, 133, 134. 135, 284, 285 Heating, effect on antiscorbutic proper- ties of food, 232 Heating, effect on nutritive value of milk. 277 and ff Hemiceiluloees interfering with extrac- tion of .4 from plant tii^sues, 112 Hemorrhage, intestinal, relation of vita- min de&cieDoy to, 311 375 SUBJECT INDEX Heredity in rickets, 193 Hippuric acid, excretion of by pellagriDS, 246 Histidine, 122, 126, 259 HistologjciLl changes of ribjunction due to lack of A, 99 Historical development of viiaouD theory, 6 "Hold" paateurixatton, 278, 283 Hormonee. 6. 185. 186, 187 Hone-flesh, antineuritic substance from, 117 Hydrochlonc acid, administration to peUa^ns of, 25S Hydrochloric acid, alcoholic, aa extrac- tive for B, 118 Hydrochloric acid, inoctivation of B by. U8 Hydrogen ton concentration of foods in relation to antiscorbutic power, 133, 134 Hydrogen ion concentration, influence on thermostability of C in tomato juice, 102 (footnote) Hydrogen peroxide, destruction of C by, 133 Hydrogeaated fats in diet, use of, 301 Hydrogcnnted oils in basal diets, fiK Hydrogenation, effect on vitamin con- tent of oils, 90, 113 Hydrolysis, acid, effect on rice polishings, 118, 119 Hydrolysis of carbohydrates, beriberi caused by abnormal, 211 Hydrox>'l ion, effect on C, 134 Hydroxy-nicotinic acid, antineuritic pro- perties of, 128 Hydroxy^yridines, antineuritic proper- ties of, 129, 182 Hydroxy-pyridine glutasine, 128 Hydroxy-pyriraidinea, 127, 128 H>'poradrcnalinemia due to lack of B, 171, 172 nium, effect of lack of B on, 173 Inoctivation of B by acids, 118 Inacttvation of vitamins, theory of, 129 Inanition, chronic, due to lacJc of B, 171,311 Index of cereals, vitamin, 132 Indican in beriberi, 172 "Indicator limit" of phosphorus pent- oxide, 80 Indole derivatives, antineuritic proper- ties of, 182 lofontUe scurvy, 219, 220 Infantile scurvy, secondary factors in, 285 Infection and nutritional disorders, relatioo between, 310 Infection, bacterial, relation of vitamin deficiency to, 311 Infection, relation between vitamin de- firiencv and susceptibility to, 167, 172, 173 Infection, relation of vitamin de6ciency and susceptibility to, 310 Infection, susceptibility of scorbutic auiinals to, 219 Infection theory* of beriberi, 202, 209, 210 Infection theory of pellagra, 245 (foot- note), 247, 248. 260 Infection theory of rickets, 193 Infection theory of xerophthalmia, 237, 238. 239 Infiltration, fatty, due to lack of B, 173 Influence of diet on vitamin-content of body fats, 70 Influenxa bacillus, 317, 318 Infusorial earth as absorbent of B, 118 Inorganic elements in nutrition, study of. 206 Labrador, outbreak of beriberi in, 206 Lactolbumin, 54, 262, 263 LactaJbumin an incomplete protein, 267 268 Lactalbumin and lactose, supplementary relation between, 267 Lactalbumin as supplement for maixe protein, 54, 208 Lactalbumin, biologic value of, 55, 266, 267, 268 Lactalbumin in the digestive tract, proc- ess of hydrolysis of, 267, 268 I>actation, diet during, 272, 273, 294, 295 LactatioD, undcrfoccding cause of failure in, 272, 273 Lactation, vitamin requirements during, 294, 295 Lactoglobulin, 202, 264 Lactose an ingredient of experimental diets, 15, 57 Lactose and lactalbumin, supplementary relation between, 267 Lactose compared with cane sugar, physiulofcical efficiency of, 262 Lactose, effect of heat on, 280 Lactose in milk, 2ti2 Lard, digestibility of, 69 Lard manufacture as influencing vitamin content of proiluct, 70, 71 Lard substitutes, digestibility of, 69, 70 Lard substitutes, vitamin content of, 113 Lord, vitamin content of, 69 Laxative diets, scurvy produced on, 227 Leaf, amino-acid content of, 52 Leaf and seed mixtures, biological value of, 52 Leaf OS supplement to food in diet, £2 Leaf, biological value of, 52 Leaf, mineral content of, 52 Leaf, protein content of, 52 Leaf tissue, thermostability of A in, 92 Leafy vegetables, antiscorbutic value of, 85, 232 Leaves, content of A in, 72, 73, 74 Leaves, extraction of A from, 77 Leaves, green, syntheMS of A by, 77 Lecithalbumin, 2f>4 Lecithin, 7, 8, 15, 112 Legume and cereal mixtures, biolo^cal value of, 50 Lemon juioe as antiscorbulto, 83 «^M ImmmhM, itfecte ok iiefa«% 64, CS LfBKcd oil, MtneUtk nkw «<, IM^ lf7 Lkb enU, feedi^ expoaBeati wi&, IM lipowfa, ■■ntiitkm of il wiOt, 131 lipOHK liMjH I— liflil J of, 8 lipocfarome*, 76, 112 T ipof hiwi i ri.w i nr mtionwithTitMBiD^, 7« Iqiochrome-like ■nhrtartrf in poric fircr, 77 lircr M core for xerophtluinua, 235 Lnrer, effect of lade of il on, 100 Lmr, effect of kek of A oo, 171, 173 Lnrer. ox, antineoritic vmhie of, 83 liver, piji^ dried, content of ^ in, 91 lAver, pork, cftrotiunds in, 7ft, 77 liver, rat, as antiscorbutic, 166 Liver, seal, as antiscorbatic, 230 Liver tissue, content of B in, 82 Liver, vitamin content oi, 182 Lloyd's reagent, 118, 142, 163 Lloyd'^ reagent, "activated," 142 Lloyd's reagent as absorbent of B, 118 Ixing-continued experiments, necessity for, 26, 27, 45 Lozenges, antiscorbutic, of Bassett- Bmitfa, 144, 145 fdaliaa daeyof a nd, 2K liah, aatiMortiatK vakie of, 84 Malt extnci, aatincUtie valoe of, 106 Man, aiaecptibaity to lack of tmti- ■eori witi e, 106 Mangel, eonteot of ^ in, 73^ 75 Maz«d, eontent of B in, 82 "Bfarmite," 215 Mastic as abaotbcnt of B, 117 "Matok" as antaeotbntie, 230 Heat, alcohol extnetion of B fran, 115 Meat, antiradkitic vahw of, 107 Meat, antiscorbutte vahie of, 80, 87, 228, 232 Meat as supplement to wheat floor, 65 Meat, biolopcal vahie of {xotein of, 258 Meat, cooked, vitamin content of, 303 Meat, content of ii in, 71 Meat, content of B in, 119 Meat, effect of alkali on B in, 110 Meat, ether extraction of B from, 116 Meat, extraction <rf B from, 115 Meat extracts, antiscorbutic value oS, 88 Meat, frozen, antineuritic value of, 07 SUBJECT INDEX 379 Meat, frosen, antiscorbutic value of, B8, 110 Meat, growth-promoting value of, 197 Meat juice, antiscorbutic value of, 88 Meat, preserved, antiflcorhiitic value of, 87 Meat, raw, aatineuritic value of, 97 Meat, Baited, antineuritic value of, 97 Meat, et«rili2ed, deficiency in anti- neuritic power, 97 Meat, gtimulattng effect of, 197 Meat, theraaoetabOity of B in, 97 Meat, thermostability of C in, 110 Meat, tinned, antiscorbutic value of, 87 Medulla, adrenal, degeneration due to lack of r, 177 Meningococcus, growth-etimulanl for, 317 Merrell-Soule proceaa for drying fruit juices, 147 MerrcII-Soule process for drying milk, 287 Metabolism, basal, xiii Metabolism, calcium in scurvy, 228, 229 Metabolism, calcium, relation of vita- mins to, 177 Metabolism, chlorine, in scurvy, 228 Metabolifim, fat, relation of vitamins to, 179. 180 Metabolism, function of hormones in, 186 Metabolism in pellagra, 245, 346 Metabolism, nitrogen, effect of hick of B on, 184 Metabolism, nitrogen, relation of vita- mins to, ISO Metabolism of nerve tiseuea, relation of tf to, 183 Mabolism, phosphorus, relation of vitaminji to, 179 Metabolism, protein, in scurvy, 218 Metabolism, relation between appetite and, 176 "Metagen," 149 Methods of concentration of vitamin B, 137 and ff Methyl alcohol, solubility of B in, 116 Mice, feeding experiments with, 2, 6, 8, 14, 16, 17, 18, 63, 181, 305 (footnote) Milk, albumin in dried, 287 Milk an ingredient of experimental diets, 3, 6, 8, 9, 10, U, 47, 86, 104 Milk, antineuritic value of, 269 Milk, antiscorbutic value of, 86, 232, 277 Milk as supplement to cereal graina 265, 266 Milk as supplement to oats and bran in guinea-pig rationa, 86 Milk as supplement to wheat flour, 55 Milk, autodaved, as constitutcnt of scorbutic diet, 104 Milk, biological value of protein of, 258 Milk, boiled, digestibility of. 279 Milk, boiled, nutritive value of, 279 Milk, breast, of pellagrins, 246 Milk, breast, of women with beriberi, 202 Milk, oalrium in dried, 2M7 Milk, caseinogen in dried, 287 Milk, composition of human compared with cow's, 261 and ff MUk, condensed, antiscorbutic value of, 104, 165 (footnote) Milk, condensed, in infant feeding, 295 Milk, condensed, nutritive value of, 282, 283, 286 Milk, condensing of, 165 (footnot«) Milk, constituenta of. 261 Milk, content of B in, 81, 82, 151, 269, 297 Milk, content of C In, 269, 270 Milk, cow's, in infant feeding, 395 MQk diet, growth on, 270, 271 Milk, dried, antiscorbutic value of, 104 271, 288, 290, 291 Milk, dried, in infant feeding. 295 Milk, dried, vitamin content of, 288 Milk drying, Just-Hatnmker process 286, 287 Milk drying, McClendon's method, 146 147 Milk drying. Merrell-Soule process, 287 Milk, effect of diet of lactating animal on composition of, 164, 165, 272^293, 294 Milk, effect of diet of lactating animal on nutritive vaiue of, 273, 274, 275, 276, 293, 294 Milk, effect of diet of lactating animal on vitamin content of, 82, 164, 165 Milk, effect of heat on nutritive value of, 277 and ff Milk, effect of heat on phosphorus con- tent of, 283 Milk, effect of heat on vitamin content, 283 Milk, effect of small quantities in the diet, 3 Milk, evaporated, in infant feeding, 295 Milk, evaporated, nutritive value of, 282, 286 Milk, factors influencing content of A in, 74 \m. Normality, criteria of, 25, 26 109 Nuclear fecundation a junction of vita- Orange juice, minimum antiscorbutic mins, 181 dose for guinea pig, 232 Nuclear material, correlation of vitamin Orange juice, thermostability of C in, content with, 182 103, 104, 100, 133 Nuclear starvation, lack of vitAmins a Orange peel as source of £, 171 (footnote) cause of, 181 Oranges, antiscorbutic value of, S3, Nuclear tissues, content of B in, S2 229, 230, 232, 298 Nucleate, sodium, an ingredient of Oranges, content of A in, 74, 197 synUictic diets, 7 Oranges, content of B in, 82, 151, 171 Nucleic acid, 127, 187 (footnote) "Nucleua" of vitjimins, 129 Orgamc foodstuffs, ix, x Nutramine, 215 (footnote) "Oriflamma,"217 Nutritive requirements of different Oridiiwt^l26 species. 20, 21 Orycifita^ bacterial growth-stimulant in, Nuts, content of vitamin A in, 74. 1 SUBJECT INDEX Orypttn, 311 OtTianin, 123, 124 OsteogBDeBis in rata on diets deficient in A, 170 Osteomalacia, acidosis a factor in, 193 Ovary, effect of lack of B on, 171, 173, 174 Orary, storage of vit&mins in, 164 Oxidation a factor in the destruction of A, M Oxidation a factor in the destruction of C, 100, 103, 133, 285 Oxidation a factor in the deterioration of heated milk, 2S5 Oxidation proceaaes, relation of anti- neuhtic vitamin to, 187 Oxygen, deterioration at A in oil throu^ contact with, W j "Paddy" rice, 212 Pal&tability a factor in nutrition, 7 Palm oil, deslructiun of .4 by steam, 92 PancreBB, content of B in, 82 Fancreaa, effect of lack of B on, 171, 173 Pancreatic extract, separation of B from^ 141, 142 Pancreatic insufficiency, relation of vita- mins to, 172 Pancreatic juice, stimulation of flow by, 186 Pancreatic secretin, resemblance of B t*j. 186 Paper pulp as roughage, 103 Paralytic s>'raptoms in iwlyneuritis, oauK of, 172 Puteurioation of milk, 277, 278, 282 Pasteurization, effect on antiscorbutic value of milk, 284, 285 Pasteurised milk as infant food, 235 Peanut butt<T as medium for administra- tion of vitamins, 148 Peanut, content of A, in, 74 Peanut me&l, antineuritic value of, 215 Pea protein, biological value of, 50, 51, 52 Peara, content of B in, 82, 171 (footnote) Peas, antineuritic value of, 77, 82, 215 Peas, antiscorbutic value of, 232 Peas as food for rats, 49, 50 Peas, dried, content of B in, 77 Peas, dried, thermostability of B in, 95 Peas, germinated, antiscorbutic value of, 84 Peas, germinated, thermostability of C in, 100 Peas, relation between color and content of vitamin ^1, 76 I I Pectins interfering with extraction of A from plant tissues, 112 Pellagraacommunicid>lediBeaae,248,249 M PeOagra, age of susceptibility to, 243 1 PeUarga among Turks in Egypt, 244, 257 Pellagra, <lietary hypothesis of , 249 and ff Pellagra-producing diets, 249 and ff Pellagra, etiologs- of, 120, 242 (footnote), 245 (footnote), 247 and ff Pellagra, extent in U.S.A., 242 Pellagra, feeding experiments in, 252, 253, 254 Pellagra, geographic distribution of, 242, 243 Pellagra, medication as compared with dietary treatment for, 255 Pellegra, periodicity of, 243 Pellegra, relation of moiie diet to, 242 (footnote). 204, 215 (footnote;, 216 (footnote). Pigeons, vitamin reqaitementa erf, 165 Figment in butter fat, relation <rf vita- min content and, 67 Figment, yelknr, in peas, 76 Pigments, hypothesis of leoeo com- pounds ol, 76 PSpnents, plant, correlation with vita- min A content, 75 FOocarpine, 128, 182, 183 Filoeaipine, antineuhtic pnq;wrties of, 128, 182 Pine needles, cure of scurvy by decocticni of, 217 Pituitary, effect of lack of B on, 171 Plant pigments, correlation with content of ^, 75 Plant structures, relative content of A in, 72 Plant structures, relative content of B in, 80, 81, 82 Plant tissues, complex of A eTisting in, 111 Plant tissues, content of B in, 80, 81, 82 Plant tissues, dried, as source of A, 136, 137 Plant tissues, extraction of A from. 111, 112, 136 Plants, hormones in, 186 HexuB, Auerbach's, relation of vitamin deficiency to degeneration of, 311 "Polished" rice, 212 Polyneuritis, 13, 14 Polyneuritis, cause of paralytic symp- toms in, 172 Polyiwuritis, chronic, 208, 209 Pohnnzritis. ikymji tjan of Madt nerve in. 150 Pot.iueuiiJts. defenmtkn of motor cells erf racd in. 130. 1S3 Polyneiiritis det^toped on diets contaxft- ing exeeas of vitamiiu. IM Poi_iueuiitis gaUinarium. 208 Po l iue miU a identical with bei ib e ii . 208, 2(M Polynetmtis. respintonr qnotient in. 216 ^footnote'* Polrneiiritis, grmpUmm in hinK 207, 206 Polvnenritisv sv1I^ltome in eats and dofs, 206 Poiyneuritis. time of raset in birds* 2C6 Potassium hydroxide, alcoholic, effect on extract of A, 112. 113 Potamium metabisulphite as predvm- tive for citrus fruit juices, 10^ vf<H>t- note.'- Potato, biological value of. 52. 53 Potato, contmt of vitamin £ in, $1, S3, 96, 151 Potato, dried, commereial, content of B, 96 Potato, mineral content of, 52, 53 Potato peel, content <rf B in, $1 Potato supplemented by seeds, nutritive value of, 53 Potato, thermostabiUty of B in. 96 Potatoes, antineuhtic value of« :iC3. 151 Potatoes, antiscorbutic value of, S3, ICCi 103, 135, 230. 2»S Potatoes as antiscorbutic for infants. 2^ Potatoes, content of .4, 73, 75 Potatoes, cooked, antiscorbutic value of, 85, 102, 103 Potatoes, effect of acid on stability of Cin, 135 Potatoes, effect of storing on anti*.N>r- butic value of, 105 Potatoes, sweet, content of A in. 75 Potatoes, sweet, content of B in, S2 Potatoes, swtxn, thermostability of A in, 92 Prairie dog. antiscorbutic requirement of, IG6, 220 Preservation of foods, effect on vitamin content. 90. 307 Preservatives for C in citrus fruit juices, 103, lOS ifootnote) Fteserved food, commercial uselessncas of data concemiog, $9 Properties, chemical, of B, 1^, 131 Properties of C, 132 384 SUBJECT INDEX VnMn ft fsetor in pdhfim, 287 and ff notein-bee milk, 9, 10, 11, 14» 60^ 61, to, 161, 266, 367 Vn^an-ixtt mSSk m ■oaree cf B, 380 Rtit8iik4(M mlDc, effect of Imi on, 06,280 Pnrteiik-Crae miDc, utngBn eoBtart d, 60, 61, 62; 907, 366 Frotem-free miDc, imfMimtaoa of, 60^ 61, 63 nroteiii-6ee miDc, m^duir eonteni of, 368 Frateoi jntalce, inflnoiiee on growth, 47 VMtm in the diet, rdatiaii between Tttamine and, 178, 170, 180 ftotoin meteboliBt in acarry, 218 Rotrin, niUMrical eqsearion f or powtb* ptomoting vafaie of, 65 Pkotemi, xwiiiinnMnt in diet, z noteina, ix, x, xi, 136 Ktoteina, hiotegica] ▼aloe of, xi, 54, 257, 258, 260, 364, 365, 366, 367 noteina, dlytimi of , x, zi Roteina in nuixitiGn, x, xi Ftoteina, iaohted, baotcriaX powtb- atinmlanta in, 160 Roteina, tiMTimnin eflSdenpf of, 56 Ph>teina, milk, 363 and ff Proteins of cereal grains, relative nJuee of, 56 Proteins, purified, nutritive valiw of, 6, 7, 8, 11, 12 Proteins, relative value in animal hus- bandry, 265 Protein utilization in pellagra, 246 Proteoses, 262 Prunes, content of £ in, 82 Prunes, content of C in, 83 Pruritis, effect of yeast on, 311 Pseudo-betaine, 128 Faoriasis, e£fect of yeast on, 311 Pulses in antineuritic diet, 204 Pulses, thermostability of B in, 96 Purified protein as supplement to maise kernel, 49 Purine bases from rice, antineuritic properties of, 127 Purine bases, synthesis of in organism, 187 Purines, 126 Purines in the diet, 303 Putrefaction, abnormal intestinal, in beriberi, 173 Pyrimidine bases, synthesis of in organ- ism, 187 Pyrimidines, 122, 127 fifiiinidinei^ nntiuauritie prapertiee of^ ^ 127, 138, 18 3 ^ Fjnimidinee, hydnniy, antinenritie pn^ pertiea of, 127, 138 Qnaa liUU ve detennination ai anti- aeartmtie vHamin, 83 ^^oantitotive aepaimtion of B and C, 182 Qniniwa, auliueuilic pnnwti ee ol^ 127 Qninolmic acid, 128 BablHtB, feeding experimenta with, 88, 284, 268 (footnote) BabbitB, auaceptiMity to xarophthalmia of, 284 Bachitie diets, MeOanby'a, 196, 197, 198 Badiom emanation, effect en B, 98 Badium, nmilarity between effecta of ftvitaminoaia aiid, 188 BaapboRy juice, thennoetabiUty of C in, 108 Bat, antiaeofbutic reqniremoita of, 106^ 167 Bat feedm& methoda, 23, 24 Bata, effect of deficiency <tf ^ on, 166; leo Bate, experimental methods used with, 21 and ff Rats, feeding experiments with, 3, 6, 7, 8, 9, 11, 12, 14, 15, 18, 19, 23, 24, 25, 27, 47, 48, 49, 50, 51, 53, 54, 55, 58, 64, 65, 72, 77, 80, 91, 93, 95, 98, 101, 113, 115, 117, 119, 120, 137, 142, 153, 158, 159, 160, 163, 166, 168, 169, 171 (footnote), 174, 175, 177, 179, 180, 210, 211, 236, 237, 238, 239 Rats, life cycle of, 19 Rats, polyneiuitis in, 207 Rats, synthesis of C by, 166, 167, 221 Rats, value for experimental purposes, 19 Rats, vitamin requirements of, 165 Reconstructed milk, 297 (See also En- riched milk) Reduction, effect on il, 94 Refining of oils, effect on vitamin con- tent, 71, 113 Rennin, 263 Renovation of butter, effect on vitamin content of, 74 Reproduction, inadequacy of oat kernel for, 49 Reproduction, influence of mineral con- tent on diet of, 48 Reproduction, influence of potato diet on, 53 Reproduction on diets deficient in A^ 168 SUBJECT INDEX 385 Reproduction on carotinoid-frec diet, 115 Reproduction on dried milk diet, 370 RcquirenientB of ra.i8 var>'ing wth age, vitamin, 175 Resistance, lowering of on vitamin-de- fieicnt diet, 172, 173, 237 R«^iralory quotient, effect of B on, 187 Respiratory quotient in polyneuritis, 216 Cfootnote) Rheumatic joints caused by lack of C, 179 RhizopuA nigricans, rrlation of vitamina to growth of, 315 Ribe, effect of lack of .4 on structure of, 99, 169, 170 Rice, biological value of protein of, 258 Rice bran, content of B In, 78 Rice, change in chemical composition due to poliahing. 212, 213 Rice embryo, analysis of, 213 (footnote) Rice embryo, separation of B from, 213 (footnote) Rice germ, antincuritic value of, 82 Rice grain, antineuritic and growth- promoting power compared, 154 Rice grain, structure of, 212 Rice, "paddy," 212 Rice, "polished." 78, 212 Rice, polished, a factor in beriberi, 204 and ff Rice, polished, nutritive deficiencies of, 15, 48, 213, 258 Rice, polished, starvation on diet of, 184 Rice polishings, antincuritic value of, 215 Riee polishings, effect of acid hydrolj-sis on, 118. 119 Rice polishings, effect of sodium hydrox- ide on B m, 1 19 Rice poliKhingH, extract of antincuritic, 205 Rice polishings, extraction of B by alcohol from, 116 Rico poliahingx, isolation of B from, 121, 122, 125 Rice protein, amino acids of, 55 Rice starch in basal diet£i, 57 Rice, thermuutabilitv of B in, 95 Rice toxin, 15, 210, "311 Rice, tmhuaked, antineuritic value of, 150 Rice, unmilled, thermostability of B in, 94 159 Rickets, 168, 170 Ricketa, acidoaia a factor in, 193, 194 Ricketa, beneficial effects of exercise in, 196, 198 Ricketa, calcium deficiency a factor in, 193, 195, 197, 199 Rickets, conditions predisposing to, 198, 199, 200 Rickets, deficient intenuU secretion, a factor in, 193 Rickets, domcJittcation theory of, 195, 199, 200 Rickets, effect of phosphates and lime salts on, 04. f>5 Rickets, etiology of, 193, 194, 195, 196, um, 200 Rickets, fut deficiency a factor in, 194, 190 (footnote), 199 Rickets, geographic distribution of, 192 Rickets, heredity and, 193 Ricketa, infection theory of, 193 Rickets, influence of phosphorus de- ficiency on, 65 Ricketa, relation to breast-feeding, 193 Rickets, several types of, 199 RickeU^. similar condition produced by phosphorus deficiency, 65 Rickets, social and ectmouiic factors in, 195 Ricketa, symptoms of, 190 and IT Ricketa, treatment by Vitaphos, 148 Ricketa, vitamin X as a factor in, 194 (footnote) IQG (footnote), 198, 199 Rind oil as preservative for orange and lemon juice, 103, 108 (footnote) Rolled oats in the diet, 51, 52 Roots and tubers, variation in content of A, 75 Roots, colored, content of A in, 75 Roots, colorless, content of A in, 75 Roots, content of A in, 73 Roots, content of C in, 85 Roots, thermostability of A in, 92 Roughage, 22, 23. flbvfj dOB to ofWBOikfas if food. ■ holiB ii. IM fltawfy, •tfokff 01^ 3tt and ff IPCBUlutiBg, '■'T*"'" Mlti is, SI , tLermiKlAhfi^ of ir M, M, «8^ » JrfKtHm df bimfiiCalock, S^ 99 flipiiiii III of aaUBflanCaB aad ma^ aofbutic Cbcign^ US llH»niiaii of J iBlM Wil iii aad gm w th pnmDtiiui; f A4tai% ISl; 15^ IM^ m of Sbammm 0Km, wmihai iCfltaunira, SU (iwtMto) rdalOam Utmaa iMdk «( Aod flHBvtibfily ta^ ITS „ IB , ^-v— <4 ». 933,20 fly I J M difldnB ok dfat for tabw* Mdoifa^SaS fleiffTjr, iiiiiatlle, ■yfloplom cf, 11% SIS 8eunry> latent, in children, 219, 230 Scurvy, relation between calcium meta- boliam and, 228 Scurry, noondavy (acUm in infantile, 285 Scurry, euaceptibility erf diffeient qiecioa ^ to, 220, 221 Scurvy, aymptoms of in adults, 217, 318, 219 Scurry, treatment in 18th century, 229, 230 Scutellum of com, B in, 78 Seal liver, antiscorbutic value of, 230 Seasonal variabilis of ejqjerimfmtal animals, 31 Seasonal variation in vitamin-content of milk, 276, 277 Secretin, 135, 186 Seed and leaf mixtures, biological value of, 52 Seed and tuber mixtuiee, biological value of, 53 Seed, distribution of B within, 78, 79 Seed proteins, biological value of, 60, 61, 62, 63 Seeds, content of il in, 73, 74, 75 Seeds, content of B in, 77 and ff Seeds, dry, content of A in, 77 Seeds, dry, content of C in, 83 of A,nktMa dnetokekflf laMlOvan^ lof peli^m,Sff 301^ 313 botnan, 7S vkKBtim, 308 SimmI awl MOMnie fiMtan m 4 qf nchBt^l 9B Soda lMHail% Mtritiw ina^wiiul witt bnad^ 130 Soda, effect on A in oOi, 00^ 112 Soda, effect on B in navy beans, 06 Sodium bicarbonate, effect on B in cabbage, 120 Sodium bicarbonate, effect <» B in navy beans, 120 Sodium hydroxide, effect on B in yeast, 120 Sodium hydroxide, effect on C, 133 Sodium hydroxide, effect on B, 119 Solubility of A, 111 and ff SolubUity of B, 115 and ff Soy bean, content of B in, 77, 81 Soy beans, thermostability of B in, 98 Soy bean, wheat flour as supplement tOw 77 SpermatogenesLB, effect of Lack of vita- mins on, 171 Spinach, content of vitamin A in, 72, 73, 136, 137 Spinach, content of B in, SI Spinach, content of C in, 85 Spinal cord, content of B in, 14, 152 Spinal cord, occurrence and function of vitamin in, 182 Spinal cord, condition of motor cells in poI>'neuritis, 1S3 Spinal cord, growth-promoting value <rf 14 qen, effect of lack of A on, 169 SUBJECT INDEX 387 Spleen, effect of lack of B on, 171, 173 Spleen, storage of vitamins in, 164 Spray process for dr\'ing of milk, 287, 291 Sprouted seeds, antiscorbutic value of, S3, S4, 232 Spruce beer, antiscorbutic value of, 84 Squash, thermoetability of A in, 02 StabiltKer of vitamins, 129 Standardization of methods of vitamin raaearch, 44 Standardization of vitamin dosage, 131 Starch as supplement to milk, 270, 271 Starch in basal diets, 57 Starch, relation between vitamins and, 173 Starvation on rice diet, 1H4 Stasis, intcittinal, relation of vitamin de- ficiency to, 172, 311 Stasis, venous, relation to oedema of, 172 Steam, destruction of yi in palm oH by, 92 Sterility, lack of vitamins a factor in, 174 Sterilization of foods without lose of antiHcorbutir value, 103, 104 Sterilisation of milk, 278, 279 Sterilized cereals, feeding experiments with fowls on, 208 Sterilized diet, effect on human beings of, 203, 204 Sterilized foods, content of B in, 9S Stimulants of gastric secretion, 6, 7 Stomach, effect of lack of B on, 171 Stomach, effect of lack of vitamins on, 171, 173 Storage, effect on antiscorbutic value of cobbage, ia5, 100 Storage, effect on antiscorbutic value of carrots, 105 Storage, effect on antiscorbutic value of dandelion leaves, 105 Storage, effect on antiscorbutic value of foods, 105 Storage, effect on antiscorbutic value of potatoes, 105 Storage influcnrc of on vitamin content of butter, 74 Storage of vitamins iu animal body, 5S, 164, 167, KfH Streptococci, growth-stimulant for, 160 String beans, variation in anti^orbutic value of, 84 Structure of vitamin A, 112 Structure of vitamin B, 128 (footnote), 129 Suhrutaneoua administration of vita- mins, 184 Sugar an ingredient of experimental diets, 6, 8, 10, 14 Sugar beet, content of A in, 73 Sugar cane products a factor in pellagra, 247 Sugar in blood, predisposition to beri- l>eri caused by excess of, 202 Sulphur a constituent of B, 132 Sulphur in laotalbumin, 263 Sulphur in protein-froc milk, 268 Sulphuric acid, inaotivation of B by, 118 Summary of phj'siological function of vitamins, 188 Sunlight a factor in onset of pellagra, 247 Sunlight, remedial effect in rickets, 195 Susceptibility of scorbutic animals3[to infection, 219 Susceptibility to infection, effect of lack of vitamins on, 172, 173 Sufito, 149 Sweat glands, stimulation by vitamins, 184 Swedish turnip, content of C in, 85, 232 Swedish turnip juice, thermostability of C in, 101 Swcetwort, antiscorbutic value of, 84 Swine, feeding ejcpenments with, 25, 47, 48, 70, 194 (footnote), 221, 265 Swine, nutritive requirements compared with those of rats, 20 Swine, poIjTicuritis in, 207 Swine, scurvy in, 221 SjTnptoras of beriberi, 206, 207 Symptoms of deficiency of A, 167 and ff Symptoms of deficiency of B, 170 and ff Symptoms of deficiency of C, 177, 178 S>-mptoms of guinea-pig Bcurv>', 221, 222, 223 Symptoms of pellagra, 243 and ff Sj-mptoms of pol>-neuriU8 in birds, 207 Symptoms of polyneuritis tu cat*, 208 Symptoms of polyneuritis in dogs, 20S Symptoms of rickets, 190 and ff Symptoms of scurvy in adults, 217, 218, 210 Synthesis of vitamins, 77, 164, 166, 167, 316 SyntheMis of B by bacteria, 160, 101 Synthesis of B by yeast, 43, 314, 315 Synthesis of C by chickens, 221 Synthesis of C by rati*, 166, 221 Synthetic dieU, 2, 6 and ff Syphilis, relation of riuketa to, 193 SUBJECT INDEX TiblBli, Titamin, 148 Tadpolen, vitemia raqpiirament of, 168 TBohniquB of ▼itamm iatlU, 25, 38 Teeth, effect of Titamiiit on oaldfie*- tkm of, 177, 178 Tempentun oopdi ti oM, reguktion of in feeding eiperiment^ 22, 28 Tempenture, inflwrnne on destruction oiBbk OAbbftgB, 99, 100 Tempenture meMoramente, emm in, 80 Tempentuie, nUtioa between E»te of deatnifitiTe of C and, 185 Teetao, degeneratiQn on vitnmin^fiea diet, 162 (footnote), 169, 174 Teeticlee, effect of lack of B on, 171, 173, 174 TeatideB, atorage of vitamins in, 164 Tosts for B, oobv, 131 Test for C, 135 Tetbelin, antinearitie properties of, 128y 182 Tetrahydrozy pyridine, 128 Tlieoty of ntamin action, 129, 130 TlwrmostabiUty of A, 90^ 01 Tliennostahility of antineuritie and growth^iroinoting fsctor cmqiaied, 164 and ff lliermostability of S, 04 and ff Thermoatability of B in presence of alkalis, llO, 130 Thermostability of C, 133 Thermostability of C in absence of oxidizing agents, 133 Thermostability of C in milk, 284, 285 Thermostability of C in orange juice, 133 Thermostability of vitamin C in presence of acids, 134, 135 Thermostability of C in presence of alkalis, 134 Thymin, 123, 127 Thymus, content of £ in, ^ Thymus, effect of lack of B on, 171, 173 Thymus, concentration of B from, 138, 139 Thymus, storage of vitamins in, 164 Th3maus, vitamin content of, 182 Thyroid, desiccated, antineuritie pro- perties of, 128 Thyroid, effect of lack of B on, 171, 173 Thyroid, effect of lack of C on, 177 Thyroid, concentration of B from, 139 Thyroxin, antineuritie properties of, 128, 182 Time curve of destruction of C in tomato juice, 102 Tikitiki extnuit, 235 T!mothy,ocmtsntof A in,73, 7S, 186, 117 Timothy, eontsat of B in, 81 Timothy, dried, as source of A^ 187 Tissues, effect of lack of A on, 167, 169 Tissues, effect of lack of Bon, ITlaadff Tissues, effect of lack of C on, 177 TisBosa, moseuiar, effect of lack of vita- mina on, 172 Tissues of polynieuiitio birds aa aouree of antineuritie, 167 Tomato, antiaoatbutie value of, 88» 382 Tomato as aatisoorbutae for infanta^ 306 Tomato, content of B in, 81 Tomato, cooked, antisoorbotio vafaw «^ 101 Tomato, dried, as aouree of A, 186 Tbmatoes, canned, aatineuzitio valna vi, 101 Tomatoei^ oanned, aatiMiorbatiB valna of, 101 Tomatoes, oanned, vitamin oontent o^ 102 Tomatoes, content <rf A in, 74 Tomatoes, dried, aa aouree of C, 108 Tomatoes, firesfa, doascs for proteetion agsinst scurvy, 101 Tomatoes, thermostability of B in, 06 Tomatoes, thermostability of C in, 101, 102 Tomato juice, canned, use in infant feed- ing, 102 Tomato juice, dried, antiacorbutus nlue of, 109 Tomato juice, thermostability of C in- fluenced by hydrogeoation conoentra- tion, 102 (footnote) Tomato-eeed, content of A in, 73 (foot- note) Tooth defects due to lack of vitamins, 178, 292 Tooth defects in scurry, 217, 218, 222, 223 Tooth defects, relation of vitamins to, 309 Tooth-formation and vitamin supj^, relation between 177, 178 Torulm, 122 Toxicity of common foodstuffs, 33 Toxicity of cotton seed, 32 Toxicity of magnesium, 32 Toxicity of peas, 50 Toxicity of rice, 15, 210, 211 Toxicity of wheat embryo, 48 Toxin a factor in pellagra, 258 (footnote) Toxin, beriberi, 210, 211 ^ SUBJECT INDEX 389 ] ^P Toxinfi ia yeast test for B, 3S Uric acid reagent, 131 ^^^| Trihydroxy pyridines, antineuritic prop- Urethritis, effect of j'east on, 311 ^^^| erties of, 128 Urtirraria, effect of yeast on, 311 ^^H Triolein an ingredient of synthetic diets, Utilization of nitrogen, effect of lock of ^^^| 8 vitamins on, 180 ^^H Tripalmitin an ingredient of fiynthetic ^^H diet.s, 8 Valine, xi, 125 ^^| Tritttearin an iogredieot of synthetic Variability of B in tissues of the same ^^^| diett, 8 type, 81,82 ^^M Trophic exchanges, regulation by vita- Variabilitv of experimental nnimaln, 27, ^^H mtna, 162 (footnote) 28, 29, 30, 31 ■ Trunitik, 287 Variation In development of cbildreDt ^^^| Trjptophane, xi, 54, 55, 258, 259 cause of, 299 ^^^| Tubcrcutoeiit a result of vitamin defi- Variation in nutritive value of vegetables ^^^B cicDcy, 310 with Bge, 101 ^ Tuberculosis, influence of lack of vita- Variation in vitamin requirements of M mins on susceptibility to, 172 individuals, 30, 31, 58 1 Tubercndosis, pellagra in patients on Variation of vitamin requirements with ^^^^ diet for, 260 age, 175 ^^H Tuberculofii'^, scurvy in children on diet Vasoconstriction, 173 ^^^H for, 232 Vasodilation, 174 ^M Tubers, amino acids in, 54 Vasomotor disturbances, lack of vitamins H Tubers, and roots, variation in content a factor in, 174 H of A, 75 V'egetable as compared with animal ^^H Tubers and seed mixtures, biological protein, biological value of, 258 ^^^| value of, 53 Vegetable fats, antirachitic value of, ^^^| Tubers, biological value of, 52, 53 198 ^H Tubers, content of A, 73 Vegetable fata and oils, content of A ^^H Tubers, mineral content of, 52, 53 in, 71 ■ Tumors, relation of vitamins to, 181, Vegetable foods as source of vitamins in ^^^| 309 (footnote) tlie diet, 304, 305 ^^1 Tumors, vitamin content of, 182 Vegetable oils, 12 ^^H Turnip, content of B in, 31, 82 Vegetable oils, effect of hydrogcnation V Turnip, content of C in, 85, 221, 232 on vitamin content of, 113 ^^fl Turnip jui(% as source of C for infant Vegetable oils, processed, investigations ^^H feeding, 296, 298, 299 114 ^H Turnip juice, Swedish, thermostability Vegetables, antiacorbutic value of, 84, ^^H of C in, 103 85,86 ^H Turnip, sH-edisfa, thermostability of C Vegetable soup as milk diluent in infant ^^H in, 101 feeding, 296 V Turtle soup, antiscorbutic value of, 86 Vegetables, scurvy developing on a diet Typhoid bacillus, vitamin content of, route ining, 86 317 Vegetables, variation in nutritive value Tyrosine as supplement to lactalbumin, with age, 101 267, 268 Velvet bean, C!corgia, content of A in, 73, 74 (footnote) Ultraviolet rays, effect on .4, 91 Velvet bean, Georgia, content of B in, 74 Unbalanced diet a factor in pellagra, 257 (footnote) Unbalanced diets, vitAmin requirement Velvet bean, Georgia, thermostability of on, 257 A in, 92 UniTenity cream, 296 Venous stasis, relation to oedema of. 172 Unpalatability of synthetic diets, 7 Vitamin .4 in fats, distribution of, 06 Uracil, 123, 127 and ff ^^H Urea in blood, effect of lack of B oc^ 174 Vitamin A in leaf, 52 ^^^| Urea in milk, 2G2 Vitamin A in infant feeding, sources of, V Uric acid in milk, 263 290 ^M 390 SUBJECT INDEX Vit&mJn Af requirement of in human nutrition, 108 Vitamin A, atructure of, 112 Vitamin A, syntbests by pl&nts, 77 ViUmin action, theory of, 129, 130 Vitamin B, color teeta for, 131 Vitamin B, discovery of, IS Vitamin B, dijstribution within seed, 78, 70 Vitamin B, effect in infant feeding, 296 Vitamin B in foodituffs, 77 and ff Vitamin B, relative amounU in plant tianios, 80, 81 Vitamin B, symptonu of deficiency of, 170 and ff Vitamin B, variability of in tiflmiee of tbe lame type, 81, 82 Vitamin-chocotat«, 148 Vitamin content, correlation vrilh func- tion. 74, 75 Vitamin D, 159. 314 Vitamin D, separation from autolysed yeast, 159, 100 Vitamin deficiency in children, symp- toms of, 292 Vitamin hyiMthosis of Funk, 13, 10 Vitamin index, 80, 162 (footnote) Vitamin, nomenclature, 3, 4, 13 Vitamin requirements for maintenance and growUi, 162, 163 Vitamin requirements of adults, 300 Vitamin roquirements of diiTcrent ^lecies 165, 166 Vitamin requirements of pigeons, 165 Vitamin requirements of rats, !05 Vitamin requirements, variation in, 30, 31, 32 Vitamin research, criticism of, 34 Vitamin reserve in infanta, 399 Vitamin t«sts, technique of, 25, 33 Vitamin tfacor>', historical development of. 6 Vitamins, chemical structure of, 129 Vitamins, pharmacological action of, 129, 130 Vitamon, 149 ViUphoa, 147 Vitellin, 204 Walnut, content of A in, 74 War antem»rrhea, 174 Water in diet, ix Water, loss from the body, ix Water, solubility of A in, 112 Water, solubility of B in, 115, 153 Water-«oluble C, 16 Water-soluble vitamin, 4. 15, 16 Waxes extracted from plant leaTes by solvents, 111 Waxes in plant extracts interfering in feeding experiments. 111 Weakness of women, effect of B on, ' 311 Wet beriberi, 206, 207 Whale oil, thermostability of ^ in, 00 Whale oil, vitamin content of, 68 Wheat, biological analyns of, 46, 47 Wheat bran, content of ^ in. .^ SUBJECT INDEX 301 Xerophthalmia, resistance of mature animals to^ 240 Xerophthalmia, species susceptible to, 234,235 Xerophthalmia, symptoms of, 234, 235 Xerophthalmia, treatment for, 235, 230 Xot>phtfaalmia, two forms of, 238 X rays, siniularity between effects of avitaioinoHa and, 183 Yeaflt, antineuritic value of, 14, 77, 215, 216. 305 Yeast, antineuritic and growth-promot- ing power compared, 152 Yeaat, antirachitic value of, 196 Teaat as addition to food, 148, 305 Yeast as cure for xerophthalmia, 233, 239 Yeast, autolyzcd, antineuritic value of, 77 Yeast, autolysed, bacterial growth- stimulant in, 160 Yeast, autolyzed, effect of drying on vitamin from, 96 Yeast compared with milk as source of B, 269 Yeast compared with protein-free milk as supplement to diet, 266 Yeast, dried, as source of J9, 81 Yeast, effect of alkali on B in, 120 Yeast, effect of radium emanation on B in, 98 Yeast, growth-promoting factor in, 152 163 Yeast, isolation of B from, 122, 123, 125, 126, 127 Yeast, pressed, content of B in, 77, 82 Yeast, process for increasing edibility of, 143 Yeast, proliferation of, 313 (footnote) Yeast stimulant as distinct from B^ 169, 160 Yeast, stimulant for invertaso activity of, 160 (footnote) Ye&Ht, stimulation by viUmiiis, 31 i, dl6 Yeast test for B, 36 and ff, 120, 161, 159 Yeast test for £, comparison with rat test«, 39, 41, 42 Ye&st test for ^, .Vitamin C a confusing factor in, 39 Yeast, thermoetabOity of B in, 96 Yeast, vitamin requirements of aerobio and anaerobic varieties compared, 187 Zein, 258 Zein, bacterial growth-stimulant in, 160 Zone distribution of pellagra, 248, 249 Ui t Ri. LITERATURE OF THE CHEMICAL INDUSTRIES On our shelves is the most complete stock of technical, industrial, engineering and scientific books in the United States. The technical liter- ature of every trade is well represented, as is also the literature relating to the various sciences, both the books useful for reference as well as those fitted for students* use as textbooks. A large number of these we publish and for an ever increasing number we are the sole agents. ALL INQiriRIES MADE OF TJ3 ARE CHEER- FULLY AND CAREFULLY ANSWERED AND COMPLETE CATALOGS AS WELL AS SPECIAL LISTS SENT FREE ON REQUEST D. VAN NOSTRAND COMPANY Publishers and Booksellers 8 WARREN STREET' NEW YORK .x^^ LANE MEDICAL LIBRARY STASFORO rXIVKBSITV This book should be returned on or before the date last stamped below. B)r 1^*^^*^^^ /IM- 1-ia iiiAr. 