None
tumors of, 807 Lupus cancer, 823 Lusitanus' theory of cancer, 18 Lutein-cell tumors, 585 Lymphadenia ossium, 378 Lymphadenitis, chronic, 313 hyperplastic, 350 Lymphadenoma, 350, 352, 367 Lyfnphangiofibroma, 149 Lymphangioma, 233 cavernosum, 234, 237 clinical forms, 235 cutis circumscripta, 236 cystic, 983 cysticum, 238 cystoides, 235 development of, 235 histological structure, 234 mesenteric, 238 of eye, 237 of ovary, 239 of salivary glands, 736 origin of, 235 retro peritoneal, 238 simple, 236 simplex, 234 tuberosum, 303 multiplex, 236, 328 Lymphangitis carcinoma- tosa, 306 Lymphatic extensions in cancer of prostate, 783 invasion by sarcoma, 80 in cancer of uterus, 559 permeation, metastasis from, 76 tuberculosis, 366 Lymphatics involved in can- cer of stomach, 668 of stomach, 647 Lymph-epithelioma, 643 Lymph-nodes, endothelioma .of, 3«9, 335 clinical types, 336 etiology, 341 frequency, 336 gross anatomy, 337 histogenesis, 339 localized, 336 metastases in, 337 structure, 338 systemic form, 336 in leukemia, 354 in lymphemia, 354 metastases in, 77 Lymphogranuloma, 367 Lymphoid tissue, tumors of, 348 classification, 348 Lymphoid-cell leukemia, 362 Lymphoma, 27, 348 leukemic, 353 malignant, 380 simple, 350 etiology, 352 Lymphomatosis, systemic aleukemic, 376 Lymphomatous tumors of intestine, 260 of stomach, 260 Lymphosarcoma, 348, 380 aggressive qualities, 383 anatomic features, 381 clinical features, 381 subvarieties, 384 congenital, 390 cutaneous, 387 duration, 382 etiology, 388 extension, 382 histological character, 383 metastases in, 387 of gastro-intestinal tract, 385 of intestine, 387 of kidney, 388 of larynx, 856 of lung, 817 of prostate, 789 of spleen, primary, 391 of stomach, 386 of testis, 388, 804 etiology, 804 of thymus gland, 917 structure, 919 of tongue, 387 origin, 382 primary lesions, 383 pharyngeal, 385 regressive changes in, 383 relation of syphilis to, 246 of tuberculosis to, 246 retro peritoneal, 387 round-cell, large, 382 structure, 382 tuberculosis in, 389 types, 382 MACROCHEILIA, 238 Macroglossia, 238 Macromelia, 238 Mai perforant, 984 Maladie de Reclus, 477, 489 kystique, 485, 486 noueuse, 486, 489 Malignancy, diagnosis of, 63 effects on body, 65 on organism, 62 formation of metastases in, 62 general intoxication in, 63 infiltrative growth in, 62 Malignancy, significance of, 62 Malignant adenoma, 453, 455 of thyroid gland, 898 cystadenoma, 742 lymphoma, 380 neuroma, 431 tumors. See Cancer. Marantic type of cancer, 67 Marchand's atypical chori- oma(i 575 Mastitis, chronic glandular, 489 cyst contents in, 489 development, 489 of benign or ma- lignant process in, 491 predisposition to can- cer in, 492 progress, 489 structure, 489 treatment, 493 interstitial, 488 productive, 485 etiology, 486 glandular, 486 interstitial, 486 senile, 486 cystic, 489 Maxillae, osteoma of, 199 Maxillary antrum, carci- noma of, 721 cysts of, 721 epithelial papilloma of, 721 tumors of, 720 sinuses, tumors of, 720 tumors of dental origin, 707 Mediastinal dermoid cysts, 969 hpoma, 184 tumors in Hodgkin's dis- ease, 370 Medullary cancer of breast, 532 tumors of adrenal gland, 771 chromaffin cell, 776 with adrenalin con- tent and neph- ritic symptoms, 776 Medullocelles, 269 Meiostagmin reaction in cancer, 92 Melanocarcinoma, 872 Melanoma, 871 clinical characters, 872 course, 873 diffuse, of meninges, 439 histogenesis, 887 histology, 874 history, 871 malignant changes in, 877 modes of origin, 872 INDEX 1045 Melanoma of adrenal gland, 778, 890 of brain, 885 of breast, 505 of glans penis, 870 of intestine, 886 of liver, primary, 693 of rectum, 674 of spinal cord, 885 of uncertain origin, 887 orbital, 882 etiology of, 885 structure of, 884 pigmentation of, 879 Melanosarcoma, 872 Melanotic whitlow, 873 Meningeal pseudoneo- plasms, 443 Meninges, diffuse melanoma of, 439 endothelioma of, 315 sarcoma of, 424, 437 diffuse, 424 gross anatomy, 424 structure, 425 sarcomatosis of, diffuse, 438 multiple, 438 Meningitis arenosa, 315 serosa circumscripta, 443 Mesenteric cysts, 975 lymphangioma, 238 Mesentery, chylangioma of, 238 Mesobranchial dermoids, 967 Mesodermal elements in te- ratoma of ovary, 618 tumors of breast, 499 Mesonephric adenomyoma, 214 tumors, 610 Mesothelioma, 768 Metastasis, 76 cerebral, in cancer of breast, 531 formation of, 62 from lymphatic permea- tion, 76 implantation, in serous cystadenoma of ovary, 588 _ in chorio-adenoma, 569 in choriocarcinoma, 575 in primary epithelial tumor of liver, 680 in syncytioma, 576 in teratoma of ovary, 618 lymph-node, 77 of benign tumor, 84 ovarian, in cancer of stomach, 649 preservation of structural type in, 86 pulmonary embolism from, 84 paradoxic, 84 secondary, 84 Metastasis, pulmonary em- bolism from, tertiary, 84 susceptibility of tissues to, 86 visceral, in cancer of uterus, 561 Microorganisms in cancer, .IJ5. Mikulicz's disease, 371 Miliary carcinosis, 464 Mixed tumors, 962 of testis, 794 special forms, 965 Mixed-cell leukemia, 361 Mole, congenital, 874 pigmented, 872 of adults, 875 Mollities ossium, 292 Molluscum contagiosum, 451 Monsters, double, 955 asymmetrical, 956 symmetrical, 955 Mouth, cancer of, epider- moid, 840 Mucoid carcinoma of breast, 513 Mucous adenocarcinoma of cervix uteri, 549 degeneration in tumors, 44 glands, bronchial cancer arising from, 8li Muller's tailed corpuscles, 21 Multicentric growth of tu- mors, 36 Multiple adenocarcinoma in sclerotic kidneys, 746 hemorrhagic sarcoma, 252 neurofibroma of spinal cord, 441 sarcomatosis of meninges, 438. Muscle tissue tumors, 27 Muscles, angioma of, 225 sarcoma of, 258 voluntary, rhabdomyoma of, 222 Mycetozoa in cancer, 116 Myelogenous lipoma, 184 pseudoleukemia, 292 Myeloid pseudoleukemia, 379 Myeloma, 256 endothelial, 323 of bone, 292 albumosuria in, 293 classification, 298 clinical course, 293 erythroblastic origin, 298 etiology, 298 gross anatomy, 293 histogenesis, 297 structure, 295 of bone-marrow, multiple, 292 Myoma, 27, 203 malignum, 205 of alimentary tract, 216 of bladder, 216 of kidney, 217 of skin, 216 of stomach, 216 of testes, 217, 802 of urinary organs, 216 of uterus, 20 degenerative changes in, 210 etiology, 212 form, 208 gross appearance, 210 location, 208 microscopical structure, 211 recurrent, 265 Myosarcoma, 27, 207 spindle-cell, of stomach, 259 Myositis ossificans, 202 Myxochondrocarcinoma of salivary glands, 735 Myxochondroma, 188 Myxoglioma, 401 Myxoma, 27, 170 anatomical characters, -1?1 clinical course, 172 forms, 173 combined with lipoma, 176 congenital, of navel, 175 etiology, 177 fibromatosum of kidney, 165 location, 173 matrix, 171 of bones, 174, 175 of heart, 175 of nervous system, 173 of optic nerve, 173 of renal hilus, 766 origin, 176 , primary, 170 structure, 171, 176 Myxosarcoma of navel, 175 of ovary, 262 of renal hilus, 766 NARES, fibroma of, 1 66 melanoma of, 723 Nasal glioma, 411 polyp, 1 66 sinuses, tumors of, 720 Nasopharyngeal fibroma, ju- venile, 168 course, 169 Nature of cancer, theories of, 94 Navel, congenital myxoma of, 175. Necrotic tissue, osteoma of, 202 1046 INDEX Neoplastic hyperplasia, morphology of, 41 versus inflammatory hyperplasia, 40 Nephrogenic origin, intra- peritoneal cysts of, 976 Nerve nevus, 159 optic, neuromyxoma of, 434 Nerve-trunks, endothelioma of, 318 neurofibroma of, 155 tumors of, 427 Nervous system, myxoma of, 173 osteoma in, 200 tumors of, 27 Neurinoma, 155 Neurocytoma, 414 of adrenal gland, 772 clinical types, 774 Neuro-epithelioma, 27, 399, 405 of retina, 422 Neurofibroma, 149 / acoustic, 432 cirsoid, 156 cutaneous, 153 multiple, of spinal cord, 441 of deeper nerve trunks, 155 plexiform, 156 visceral, 155 Neurofibroma tosis, 152 visceral, 157 Neurofibrosarcoma, 155 clinical course, 156 Neuroglioma of pineal gland, ependymal, 951 Neuroma, 27, 427 amyelinicum, 427 ganglionare, 27, 427, 771 ganglionic, 430 etiology, 432 malignant, 431 myelinicum, 427 plexiform, 427 traumatic, 427 Neuromyxoma of optic nerve, 434 Neuropathic papilloma, 159 Nevus, 872 bathing trunk type, 873 cellular. cavernous angioma of, 232 chondrosarcoma of, 262 cystadenoma of, pseu- domucinous, 591 serous, 586 cystoma of, simple serous, 583 cysts of, 582. See also Cysts of ovary. dermoids of, 613. See also Dermoid cysts of ovary. endothelioma of, 309 appearance, 333 clinical course, 333 diagnosis, 333 structure, 333 fibroma of, 166 fibrosarcoma mucocellu- lare carcinomatodes of, 262, 603 lymphangioma of, 239 myxosarcoma of, 262 perithelioma of, 346 round-cell sarcoma of, 261 sarcoma of, 260 spindle-cell sarcoma of, 261 teratoma of, 613. See also Teratoma. tumors of, adrenal, 610, 762 age in etiology, 606 epithelial, 582 etiology, 606 histogenesis, 606 origin, 608 PACHYDERMATOCELE, 159 Pachydermia, 159 laryngis, 851 Pachymeningitis cervicalis hypertrophica, 443 interna sarcomatosa, 425 Paget's cells, 827 INDEX 1047 Paget's disease of nipple, 826 origin, 828 structure, 827 Pancreas, adenoma of, 702 cancer of, 702. See also Cancer of pancreas. sarcoma of, 706 tumors of, 702 Papillary adenocarcinoma of chroid plexus, 418 of kidney, 742 with granular cells, 746 adenoma of kidney, 739 of ovary, everted, 597 cancer, 464, 470 of kidney with clear cells, 743 cystic adenoma, 455 endothelioma, 305 epithelial tumors, 899 epithelioma of lip, 837 fibroma, 149 intracystic fibre-adenoma of breast, 496 pseudomucinous cystad- enoma, 592 serous adenocarcinoma of ovary, 589 Papilloma, 28, 446 bronchial, 813 clinical course, 447 development of malig- nancy in, 448 neuropathic, 159 of bladder, 860 allantoid type, 863 structure, 863 of breast, 505 of larynx, 847 structure, 847 of maxillary antrum, epi- thelial, 721 of renal pelvis and ureter, 763 of tongue, 452 of ureter, 763 structure of, 448 Papillomatosis, diffuse buc- cal, 452 Paraffin cancer of scrotum, 870 Paraganglioma, 777 Paranuclein, 46 in tumor-cells, 46 Parasites, scope of relation to cancer, 122 Parasitic fetus, 958 theory of cancer, 113 theoretic objections to, 120 Parathyroid gland, cysts of, 910 tumors of, 909 Parenchymatous goiter, 894 acquired, 895 Parosteal exostosis, 198 Parosteal sarcoma, 275 Parovarium, tumors of, 609 Pars intermedia, tumors of, 938 Pavement tumors, 28 Pelvic connective tissue, dermoid cysts of, 978 lipoma, 184 Pelvis spinosa, 185 Penis, epithelioma of, 866 course, 869 established disease, 867 extensions, 868 initial lesion, 867 structure, 869 osteoma of, 202 tumors of, 866 Pepper's type of congenital sarcoma of adrenal gland and liver in infants, 775 Peptic ulcer, cancer follow- ing, 630 Peribronchial sarcoma of lung, 817 Peri-endothelioma, 345 Periosteal sarcoma, 270 Periosteum, fibroma of, 163 Peripheral nervous system, tumors of, 152 Perirenal lipoma, 184 Perithelioma, 304, 317, 341 clinical types, 344 gross appearance, 343 of bones, 345 of breast, 345 of carotid gland, 346 of cervix uteri, 550 of kidney, 346 ' of ovary, 346 of pia mater, 344 of subcutaneous tissue, 344 orbital, 885 secondary, 342 structure, 343 Peritoneal endothelioma, 320 invasion in cancer of breast, 530 teratoid tumors, 976 Peritoneum, cysts of, 975 dermoid, 975 Perivascular endothelioma, 30.5, 339. Petrified epithelioma, 820 Phagocytosis by tumor- cells, 47 Pharyngeal dermoid cysts, 970 teratoma, 970 Pharynx, lymphosarcoma of, primary, 385 Phosphorus in tumors, 90 Physaliden of Virchow, 43, 187 Pia mater, perithelioma of, 344 Pial glioma, 414 Pigmented mole, 872 of adults, 875 Pineal gland, 948 cysts of, 949 general pathology, 948 glioma of, ependymal, .950 histology, 948 neuroglioma of, epen- dymal, 951 teratoma of, 949 tumors of, 948 classification, 949 clinical features, 951 occurrence, 948 structure, 951 symptomatology, 951 Pituitary gland, adenocar- carcinoma of, 932 metastases, 933 structure, 933 adenosarcoma of, 934 anatomy, 925 angiosarcoma of, 934 cancer of, atypical, 934 functional changes in, 928 histology of, 927 hyperplasia of, diffuse, 93° posterior lobe, glioma of, 939 lipoma of, 939 tumors of, 924 anatomy, 929 cephalic, 939 dystrophic, 940 etiology, 924 miscellaneous, 939 relation of type with symptom complex, 945 symptomatology, 939 glandules, accessory, an- atomy of, 927 Placenta, angioma of, 232 myxoma of, 173 Plasma-cell leukemia, 364 tumors, extramedullary, 388 Plastin, 46 in tumor-cells, 46 Pleura, endothelioma of, 319 involvement in cancer of breast, 529 Plexiform angioma, 224 endothelioma, 305, 339 epithelioma, 475 fibroma of spermatic cord, 80 1 neurofibroma, 156 neuroma, 427 Polyp, choanal, 167 nasal, 1 66 Polyposis, intestinal, 673 cancer following, 662 Porphyry spleen, 368 Port-wine stain, 224 1048 INDEX Post-generation of embryos 957 Postnatal tumors, 26 Precancerous changes cervix uteri, 550 _ in corpus uteri, 556 diseases, 476 lesions, 475 Pregnancy, effect of, 144 on cancer of uterus, 560 Presarcomatous lesions, 246 Presternal dermoid cysts 970 Primary acinar carcinoma of breast, 522 splenomegaly, 313 Prostate, adenocarcinoma of, 787 adenoma of, 786 cancer of, 781. See also Cancer of prostate. epithelioma of, squamous 788 hypertrophy of, 459, 779 adenomatous, 780 carcinomatous, 780 etiology, 780 productive inflamma- tion in, 779 structure, 779 lymphosarcoma of, 789 rhabdomyosarcoma of, 789 sarcoma of, 788 spindle-cell, 789 tumors of, 779 Proteins, tumor, constitu- tion of, 89 febrile destruction of, 66 toxic destruction of, 66 Protozoa in cancer, 115 Pruritus in cancer of vulva, 563 Psammocarcinoma, 591 Psammoma, 305 endothelial, of skin, 331 of spinal cord, 440 Pseudoleukemia, 366, 367 gastro-intestinal, 378 myelogenous, 292 myeloid, 379 true, 376 blood in, 377 clinical features, 377 general features, 376 histology, 376 Pseudomucinous adenocar- cinoma of ovary, 595 cystadenoma of ovary,59i Pseudomyxoma peritonei, 464, 595 rseudoneoplasms, menm- geal, 443 Psoriasis preputialis, 867 Pulmonary alveoli, cancer arising from, 812 Pulp tumors, 29 Pylorus, sclerosing fibro • carcinoma of, 639 RADICULODENTAL cysts, Rankenneurome, 156 Ransohoff's test in cancer 93.. Rapidity of growth in ma lignancy, 62 Rat, experimental cancer o stomach in, 133 Rathke's pouch, 927 Recklinghausen's disease 153 Rectum, melanoma of, 674 Recurrent myoma of uterus 265 Regeneration of blood in cancer, 69 Regenerative hypertrophy cancer from, 478 Regressive changes in tumor-cells, 43 Renaissance period, cancer in, 1 8 Renal hilus, lipoma of, 766 myxoma of, 766 myxosarcoma of, 766 sarcoma of, diffuse, 767 tumors of, 766 lipoma, 183 pelvis, epithelial tumors of, 763 epithelioma of, papil- lary, 763 papilloma of, 763 sarcoma of, diffuse, 767 Replacement lipomatosis, 181 Respiratory tract, chon- droma of, 192 Retention cysts, 32 Reticulated epithelioma, histogenesis, 833 of skin, 830 osteoma, 201 Reticulosplenome nodulaire, 391 Reticulum-cell sarcoma, 340 Retina, glioma of, 421 etiology, 423 structure, 422 neuro-epithelioma of, 422 Retrograde transport in dis- semination of tumors, 83 ^.etroperitoneal dermoids, 977 lymphangioma, 238 lymphosarcoma, 387 teratoids, 977 tumors of adrenal rests, lateral, 762 lhabdomyoma, 27, 203, 217 appearance, 217 clinical forms, 220 course, 219 form, 217 Rhabdomyoma, miscellane- ous, 222 of bladder, 866 of heart, congenital, 222 of testis, 221 of urinary bladder, 220 of voluntary muscle, 222 structure, 217 uteri, 220 Rhabdomyosarcoma of prostate, 789 Ribbert's chromatopho- roma, 872 Riedel's struma, 908 Rodent ulcer, 830 crateriform, 831 histogenesis, 833 structure, 832 Round-cell cancer of sali- vary glands, 727 sarcoma, 243, 244 of breast, 503 of lung, 817 of ovary, 261 SABER-SHEATH veins in tu- mors, 57 Sacral cystic lymphangioma, 983 hygroma, 239, 983 mixed tumors, congenital, origin of, 984 teratomas, 982 Sacrococcygeal dermoids, 979 mixed tumors, 979 teratoid tumors, 981 teratomas, 979 Salivary glands, adenoma of, 725 cancer of, 725 round-cell, 727 chondroma of, 193 lymphangioma of, 736 myxochondrocarcinoma of, 735 tumors of, epithelial, 725 mixed, 727 Sarcoma, 20, 27 alveolar, 983 alveolare epithelioides, 335 benign giant-cell, of bone, 280 capsular, 275 character of growth, 241 clinical types, 249 deciduocellulare, 566 endometrial, structure, 267 endothelioma and, com- bination of, 311 epithelioides, 303 etiology, 245 fasciculatum, 250 INDEX 1049 Sarcoma, fibroblastic, 249 general characters, 240 giant-cell, 250 benign, of bone, 280 of tendon-sheaths and aponeuroses, 256 gross anatomy, 240 Hodgkin's, 373 invasion of lymphatics by, 80 lamellosum, 250 multiple hemorrhagic, 252 histological struc- ture, 253 of adrenal gland in in- fants, congeni- tal (Pepper type), 7.75 with cranial met- astases (Hutch- inson type), 774 of bladder,. stroma of, 244 structure, 242 telangiectatic, of bone, 278 trabeculare, 250 Sarcomatoid structures in cancer of cervix uteri, 550 Sarcomatosis of meninges, diffuse, 438 multiple, 438 Sarcomatous struma, 934 Sarcome angioplastique, 797 Scapula, chondroma of, 190 Schimmelbusch's disease, 489 Scirrhous cancer of breast, 534. of cervix uteri, 549 of prostate, 788 of stomach, clinical fea- tures, 659 diffuse, 637 Scirrhus pustuleux, 534 Sclerosing fibrocarcinoma of stomach, clinical fea- tures, 659 osteogenic sarcoma, 275, 278 Sclerosing pyloric fibrocar- cinoma of stomach, 639 Sclerosis, multiple adeno- carcinoma of kidneys in, 746 Scrotum, cancer of, 870 paraffin, 870 Sebaceous cysts of breast, 505 Secondary osteoma, 200 Seminal vesicles, sarcoma of, 789 Seminome, 795 Senile involution of breasts, 487 osteomalacia, 292 Sennert's theory of cancer, 18 Serology, 89 Serous adenocarcinoma of ovary, papillary, 589 cavities, invasion of, by cancer, 80 cystadenoma of ovary, 586 cysts, 975 membranes, endothehoma of, 319 Simple cystoma, 582 lymphoma, 350 etiology, 352 mixed tumors, 28 Singer's nodes, 847 Skin, acanthoma of, 818. See also Acanthoma of skin. angio-endothelioma of, 331 cancer of, epidermoid, 818 cysts of, atheromatous, 965. epithelial, 965 endothelial psammoma of, 331 endothelioma of, 309, 328 epithelioma of, adenoid, 834 cystic, 834 simple, 835 basal-cell, 830 reticulated, 830 invasion in cancer of breast, 525 lesions in Hodgkin's dis- ease, 371 myoma of, 216 osteoma of, 202 sarcoma of, 252 spindle-cell sarcoma of, 255 Skull changes in brain tumors, 398 Small alveolar carcinoma, 47.1. cystic adenocarcinoma ot breast, 517 duct carcinoma of breast, 517 Solid ovarian adenoma, 596 1050 INDEX Solitary diffuse endotheli- oma of bones, 326. Soot-wart, 870 Spermatic cord, fibrolipoma of, 80 1 fibroma of, plexiform, 801 tumors of, adrenal, 762 Spina bifida occulta, 984 tumors associated with, 983 Spinal cord and meninges, sarcoma of, 437 angioma of, 441 degeneration of, in brain tumors, 398 glioma of, 411 lipoma of, 441 melanoma of, 885 neurofibroma of, multi- ple, 441 psammoma of, 440 sarcoma of, central, 440 metastatic, 442 solitary, 438 tumors of, 436. See also Tumors of spi- nal cord. secondary changes in, 442 symptomatology, 443 xanthochromia in, 442 membranes, relation of tumors to, 444 Spindle-cell myosarcoma of stomach, 259 sarcoma, 249 blood-vessels of, 250 diagnosis, 250 histogenesis, 251 of bone, 277 of breast, pure, 504 of intestine, 260 of lung, diffuse, 816 of ovary, 261 of prostate, 789 of skin, 254 etiology, 256 histogenesis, 255 structure, 254 of spleen, 390 rate of growth, 249 secondary changes in, 250 structure, 249 Spirochetae in cancer, 116 Spleen, lesions in, in leu- kemia, 354 lymphosarcoma of, pri- mary, 391 porphyry, 368 sarcoma of, 390 endothelial, 390 spindle-cell, 390 Splenic Hodgkin's disease 368 Splenomegaly, primary, 31^ Spontaneous cure in tu- mors, 60 regression in tumors, 40 Spotted kidneys, 741 Squamous epithelioma of prostate, 788 Squamous-cell cancer of choroid plexus, 419 of large intestine, 674 Stain, port-wine, 224 Stammler's reaction in can- cer, 93 Stenosing fibrocarcinoma of large intestine, 670 Sterility in etiology of uter- ine tumor, 212 Sternberg's disease, 367 Stomach, adenocarcinoma of, 627 occurrence, 656 adenoma of, simple, 629 athletic, 652 cancer of, 625. See also Cancer of stomach. endothelioma of, 335 fibrocarcinoma of, dif- fuse, 639 sclerosing, clinical fea- tures, 659 pyloric, 639 leather-bottle, in linitis plastica, 644 lymphatics of, 647 lymphomatous tumors of, 260 lymphosarcoma of, 386 myoma of, 216 sarcoma of, 259 miscellaneous, 260 spindle-cell myosarcoma of, 259 tumors of, lymphomat- ous, 259 ulcerocancer of, 658 Stools, blood in, in cancer, 72 Stroma of tumors, 53 regressive changes in, 55 reactions, experimental analysis of, 55 Struma adrenalis, 461 colloid, 460 hypophysis, 461 ovarii, 615, 621 postbranchialis, 901 Riedel's, 908 sarcomatous, 934 suprarenalis, 183, 758 Strumae suprarenales aber- ratae renalis, 738 Subcutaneous lipoma, 182 tissues, perithelioma of, 344 Sublingual dermoids, 967 Submaxillary gland, epithe- lial tumors of, 737 Superficial adenoma ol ovary, 597 Sweat-glands, tumors of, 836 Syncytial endometritis, 566, 575, 577 wandering cells, 568 Syncytioma, 575 clinical course, 578 metastases in, 576 Synovial lipoma, 182 Syphilis, relation of, to lym- phosarcoma, 246 to tumors, 123, 124 Syringomyelia associated with gliosis, 412 Systemic aleukemic lympho- matosis, 376 TAIL, false, 984 Teeth, tumors of, 707 Telangiectasis, 224 Telangiectatic angio-endo- thelioma of bones, 323 bone-sarcoma, 273 sarcoma, 224 of bone, 273, 278 prognosis, 286 Tendon-sheaths, giant-cell sarcoma of, 256 Teratoblastomas, 962 Teratogenic termination period, 954, 973 Teratoid chondroma, 193 Teratoids, 959 cervical, 969 intracranial, 974 of breast, mixed, 499 of hypophyseal duct, 935 of testis, 794 peritoneal, 976 retro peritoneal, 977 sacrococcygeal, 981 Teratology, 954 Teratoma, 28, 959, 975 abdominal fetal, 977 causes, 961 cervical, 969 intracranial, 974 morphogenesis, 960 of orbit, 970 of ovary, 613 anatomy, 613 atrophic bidermal, 619 clinical course, 613 contents, 615 dermoids and, differ- entiation, 615 etiology, 623 mesodermal elements in, 618 metastases in, 618 multiple, 619 prognosis, 613 relation to simple tu- mors, 622 with cystoma, 614 of pineal gland, 949 of testis, 790 INDEX 1051 Teratoma of testis, adult, clinical course, 794 derivatives, 790 historical note, 790 metastases in, 800 relation to miscellane- ous tumors, 801 structure, 797 varieties, 790 pharyngeal, 970 sacral, 982 sacrococcygeal, 979 source, 960 special forms, 965 tridermal, 977 Teratomatous glioma, 415 Testicular adenoma of ovary, 610 Testis, adenoma of, 802 cancer of, embryonal, with lymphoid stroma, 795 chondroma of, 801 chorioma of, 797 embryoma of, adult, 790 complex, 790 endothelioma of, 308 fibroma of, 165, 801 interstitial cells of, hyper- plasia of, 803 lymphosarcoma of, 388, 804 etiology, 804 myoma of, 217, 802 rhabdomyoma of, 221 sarcoma of, 795, 802 teratoma of, 790. tumors of, adrenal, 762, 803 embryoid, 794 embryonal, 795 miscellaneous, relation to teratoma, 801 mixed, 794 teratoid, 794 Theory of cell autonomy, 97 Thiersch's theory of cancer, 23 Thoracic duct, invasion of, by cancer, 79 Thoracopagi, 955 Thymoma, 917 interpretation, 922 Thymus gland, anatomy, 912 cancer of, 920 cysts of, 915 gemeral pathology, 914 hypertrophy of, simple, 914 lymphosarcoma of, 917 structure, 919 sarcoma of, 921 tumors of, 912 classification, 917 clinical course, 923 primary, 916 Thyroglossal duct, cysts of, 969 Thyroid gland, adenocarci- noma of, 898 small alveolar, large cell, 901 adenoma of, fetal, 895 interacinous, 894 malignant, 898 cancer of, 901 . See also Cancer of thyroid gland. cysts of, 910 granuloma of, benign, 908 hypertrophy of, con- genital, 459 sarcoma of, 906 tumors of, 891 papillary epithelial, 899 structure, 900 Tibia, adamantinoma of , 7 1 5 Tissue tension theory of cancer, 98 Tongue, cancer of, epider- moid, 840 cavernous, angioma of, 231 lymphosarcoma of, 387 papilloma of, 452 Trachea, exostosis of, 198 Transplantable tumors, adaptation of, 139 fate of, 139 nature and origin of, 136 problems of, 136 Transplantation of tumors, 134 acquired resistance to, 144 between animals of dif- ferent species, 134 between lower animals of same species, 135 between man and man, 134 between related species of lower animals, 134 hypersusceptibility to, H7 influence of variations in soil, 140 natural resistance, 143 nature of factors in re- sistance, 145 passive resistance to, H5 uniformity of technic in, 140 Transplanted tumors, in- fluence of diet on, 140 resistance to, 143 spontaneous absorption of, 141 structural changes in, 141 Trauma in etiology of tu- mors, 109, no frequency, 112 mechanism, in medicolegal aspects, 112 Traumatic exostoses, 198 neuroma, 427 tumors, 26 Tridermal teratomas, 977 True fibroneuroma, 427 osteoma, 199 pseudoleukemia, 376 Tuberculosis cutis verru- cosa, 823 Hodgkin's disease and, 375 in lymphosarcoma, 389 lymphatic, 366 relation of, to lympho- sarcoma, 246 to tumors, 123, 124 Tuberculum impar, 910 Tubo-ovarian cysts, 584 Tubular acanthoma, 819 adenocarcinoma of kid- neys, 750 adenoma, 455 of kidney, 741 carcinoma, 471 epidermoid carcinoma, 474 Tumeur a medullocelles, 269 a myeloplacques, 269 Tumor-cells, anaplasia of, 101 miscellaneous, peculiari- ties of, 46 phagocytosis by, 47 regressive changes in, 43 Tumor-like hyperplasia of endothelium, 313 Tumors, adrenal, hepatic, 762 of female genital organs, 762 of spermatic cord and testis, 762 rest, 755 carcinomatous, 759 gross appearance, 757 lateral retroperito- neal, 762 occurrence, 756 peritheliomatous, 759 renal tumors and, differentiation, 760 sarcomatous, 759 structure, 758 trabecular, 759 adult, 26, 48 alveolar, 346 amitosis in, 39 amyloid, 167 associated with spina bi- fida, 983 autogenous antigen of, complement deviation with, 91 1052 INDEX Tumors, benign, malignant transformation in, 64 metastasis of, 84 blood-vessel lesions in, 57 cell division in, 38 central growth in, 31 chemistry of, 89 classification, 26 collateral hypertrophy in, 37. colloid degeneration of, 45 color of tissue, 29 complex tissue type, 28 congenital, 26 connective-tissue type, 27 consistence, 30 course, 59 cystic, 464 of carcinomatous struc- ture, 464 cysts in, 31 definition, 25 desmoid, 164 effects on body, 65 emaciation from, 65 embryonal, 26, 49 encephalpid, 511 endothelial type, 27 epithelial type, 28 general pathology, 446 etiological classification, 26 etiology of, special, 109 expansive growth, 25 experimental production of, 126 by x-ray, 132 chronic inflammation in, 131 effect of extract of human tumors, 132 study of, 118 extensive growth, 25 fats in, 90 fatty degeneration in, 43 febrile destruction of pro- teins in, 66 ferments in, 67, 90 heterolytic action of, 67 functional activity in, 53 gametoid mitosis in, 39 general morphology, 29 glandular, 28 glycogenic degeneration of, 44 growth of, 31, 48 hereditary, 26 histioid, 48 histological classification, 26, 27 histopathology, 34 homologous, 48 homotypic, 48 hyaline changes in, 45 hydropic degeneration in, 43 infiltrative growth, 25, 31 Tumors, inflammatory reac- tion in, 50 intermittent periods of growth of, 59 lactic acid in, 89 local circumscription of, 29 extension of, 50 lutein-cell, 585 lymphomatous, of intes- tine, 260 of stomach, 260 malignancy in, signifi- cance of, 62 markings of, 30 maxillary, of dental ori- gin, 707 mesonephric, 610 mixed, 962 sacral congenital, ori- gin, 984 special forms, 965 modes of origin, 36 mucous degeneration in, 44. multicentric growth of, 36 muscle tissue type, 27 natural limit in course of, 59 nervous system type, 27 nomenclature, 26 of adrenal gland, 768 classification, 768 medullary, 771 chromaffin cell, 776 with adrenalin con- tent and neph- ritic symptoms, 776 of bile-ducts, 689 of bladder, epithelial, 860 miscellaneous, 865 of brain, 393 age incidence, 393 anatomical classifica- tion, 398 choked disk in, 398 circulatory disturb- ances in, 398 destruction of tissue in, 397. duration, 396 edema in, 397 general considerations, .393 distribution, 395 heredity in, 393 meningeal complica- tions, 398 occurrence, 393 operability, 395 relative frequency, 394 secondary effects of, 3?6 sex in, 393 skull changes in, 398 spinal cord degenera- tion in, 398 Tumors of brain, trauma in etiology, 393 of breast, ectodermal mixed, 500 epithelial, 484 mesodermal, 499 miscellaneous, 505 mixed, 494 teratoid mixed, 499 of choroid plexus and ependyma, 415 etiology, 416 gross appearance, 416 structure, 416 of epoophoron, 609 of extrarenal adrenal rests, 761 of Fallopian tubes, 612 adrenal, 762 of Gasserian ganglion, 434 of hypophyseal duct, 935 of hypophysis, 924 of infundibular ependy- ma, 420 of intestine, multiple be- nign embryonal carci- noid, 663 of kidney, 738 adrenal tumors and, dif- ferentiation, 760 epithelial, 738 classification, 739 of lacrimal gland, 319, 725 of larynx, 847 benign, 850 of liver, 675 classification, 675 primary epithelial, 678 anatomical varie- ties, 681 clinical course, 680 varieties, 68 1 etiology, 678 histogenesis, 679 metastases in, 68 1 relation to cirrho- sis, 678 of lung, 807 of lymphoid tissue, 348 classification, 348 of maxillary and nasal si- nuses, 720 of nerve trunks, 427 of ovary, adrenal, 610, 762 age in etiology, 606 epithelial, 582 etiology, 606 histogenesis, 606 origin, 608 simple, relation to tera- toma, 622 of pancreas, 702 of parathyroid gland, 909 of parovarium, 609 of pars intermedia, 938 INDEX 1053 Tumors of penis, 866 of peripheral nervous sys- tem, 152 of pineal gland, 948 classification, 949 clinical features, 951 occurrence, 948 structure, 951 symptomatology, 951 of pituitary gland, 924 anatomy, 929 cephalic, 939 dystrophic, 940 etiology, 924 miscellaneous, 939 relation of type with symptom complex, 945 symptomatology, 939 of placenta, 232 of prostate, 779 of renal hilus, 766 pelvis and ureter, epi- thelial, 763 of salivary gland, epi- thelial, 725 mixed, anatomy, ..734 clinical course, 733 etiology, 733 structure, 735 mixed, 727 of spinal cord and mem- branes, 436 age incidence in, ,437, classification, 437 duration, 445 etiology, 436 trauma in etiology of, 436 extradural, 444 extramedullary, 444 intramedullary, 444 level of, 443 relation of, to cord, membranes, and vertebrae, 444 secondary changes in, 442 symptomatology, 443 vertebral, 445 xanthochromia in, 442 of stomach, lymphomat- ous, 260 of submaxillary gland, epithelial, 737 of sweat-glands, 836 of teeth, 707 of testis, 790 adrenal, 803 embryoid, 794 embryonal, 795 mixed, 794 teratoid, 794 Tumors of thymus gland, 912 classification, 917 clinical course, 923 primary, 916 of thyroid gland, 891 epithelial papillary, 899 structure, 900 of uterus, adrenal, 762 of vulva, epithelial, 562 parasitic theory of, classi- fication by, 125 pavement, 28 peripheral growth of, 31 plasma-cell, extramedul- lary, 388 post-natal, 26 precancerous stage of growth, 34 progressive growth, 25, 59 proteins, constitution of, 89 pulp, 29 rate of growth, 59 recurrence of, 86 regional classification, 26 relation of blood-vessels to, 56 retrograde transport in dissemination of, 83 saber-sheath veins in, 57 sacrococcygeal, mixed, 979 simple mixed, 28 spontaneous cure in, 60 regression in, 40 stroma of, 53 retrogressive changes in, 55 structure, 48 teratoid. texture of, 30 total quantity of blood in, 69 toxic destruction of pro- tein tissues in, 66 transplantable, adapta- tion of, 139 fate of, 139 nature and origin of, 136 problems of, 136 transplantation of, 134 acquired resistance to, 144 between animals of dif- ferent species, 134 between lower animals of same species, 135 between man and man, 134 between related species of lower animals, 134 hypersusceptibility to, 147 influence of variations in soil, 140 Tumors, transplantation of, natural resistance, 143 nature of factors in re- sistance, 145 passive resistance to, uniformity of technic in, 140 transplanted, influence of diet on, 140 resistance to, 143 spontaneous absorption of, 141 structural changes in, 141 trauma in etiology of, 109, no frequency, 112 mechanism, in medicolegal aspects, 112 traumatic, 26 ulceration in, 33 unicentric growth of, 36 ULCER, peptic, cancer fol- lowing, 630 rodent, 830 crateriform, 831 histogenesis, 833 structure, 832 Ulceration in tumors, 33 Ulcerative infiltrating epi- thelioma of lip, 837 Ulcerocancer of stomach, 658 Unicentric growth of tu- mors, 30 Urea, percentage of, in cancer, 72 Ureter, cancer of, primary, 865 ^ epithelial tumors of, 763 epithelioma of, papillary, 763 papilloma of, 763 Urethra, cancer of, 870 Uric acid increase in cancer, 72 Urinary bladder, rhabdo- myoma of, 220 organs, myoma of, 216 Urine, changes in, in cancer, Urobilin in urine in cancer, 74. Uterine fibromyoma, 207 lipoma, 184 mucosa, sarcoma of, 266 Uterus, adeno-acanthoma of, 547 cancer of, 267, 543. See also Cancer of uterus. chondroma of, 192 endothelioma of, 334 myoma of, 208 1054 INDEX Uterus, myoma of, degenera- tive changes in, 210- etiology, 212 form, 208 gross appearance, 210 location, 208 microscopical structure, 211 recurrent, 265 rhabdomyoma of, 220 sarcoma of, 263 classification, 264 etiology, 266 metastases in, 263 mural, 263 structure, 264 tumors of, adrenal, 762 VAGINA, epidermoid cancer of, 564 Varicosities, chronic, 224 Vascular nevus, 224 Verruca plana juvenilis, 448 vulgaris, 448 Vertebral tumors of spinal cord, 445 Villous duct cancer, 510 Virchow's physaliden, 43, 187 theory of cancer, 22 Visceral metastases in can- cer of uterus, 561 neurofibroma, 155 neurofibromatosis, 157 Vocal cords, acanthoma of, 855 Vulva, epidermoid cancer of, 562 tumors of, epithelial, 562 WANDERING cells, syncytial, 568 Warts, cutaneous, 448 soot-, 870 Wassermann reaction in cancer, 91 Whitlow, melanotic, 873 XANTHELASMA, 162 Xanthochromia in spinal cord tumors, 442 Xanthoma, 162 diabeticorum, 162 generalized, 162 multiplex, 162 palpebrarum, 162, 163 planum, 162 structure of, 163 tuberosum, 162 vulgare, 162 Xanthomatosis, 163 Xanthosarcoma, 256 Xeroderma pigmentosum, 822 x-ray carcinoma, 102 dermatitis, cancer and, 823 clinical course, 824 structure, 824 experimental production of tumors by, 132 ZONA glomerulosa, 758 AN INITIAL FINE OF 25 CENTS WILL BE ASSESSED "FOR FAILURE TO RETURN THIS BOOK ON THE DATE DUE. 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