None
178 cysts in, 175 etiology, 175 gastro-intestinal, 179 heterologous, 177 homologous, 177 intermuscular, 177 mediastinal, 179 microscopic structure, 1 74 molle, 173 multiple, 176 symmetrical, 176 Lipoma, myelogenous, 179 of breast, 488 of heart, 179 of larynx, 828 of posterior lobe of pitui- tary, 916 of renal hilus, 745 of spinal cord, 424 of uterus, 179 pelvic, 179 perirenal, 179 petrificum ossificans, 175 renal, 178 subcutaneous, 177 sy no vial, 177 telangiectaticum, 174 trauma as cause, 176 Lipomatosis, replacement, 177 Liposarcoma, 178 Liquefaction cysts in tumors, 32 Liver, adenoma of, multiple 665 solitary, 660 angioma of, cavernous, 227 angiosarcoma of, 672 cirrhosis of, cancer with, v 665 relation of primary epi- thelial tumors to, 657 hyperplasia of, fojal ade- nomatoid, 444 epithelial, 654 multiple nodular, 656 melanoma of, 672 regenerative powers of, 655 sarcoma of, 671 in infants, congenital (Pepper type), 753 tumors of, 654. Liver-cell cancer, multiple, 663 primary massive, 661 Localities, cancer, 114 Lung, cancer of, 785. See also Cancer of lung. extension to, in cancer of breast, 510 lymphosarcoma of, 796 reticulated osteoma of, 196 sarcoma of, 794. See also Sarcoma of lung. tumors of, 785 Lupus cancer, 802 Lusitanus' theory of cancer, 18 Lutein-cell tumors, 565 Lymph theory of cancer, 18 vessels in fibroma, 151 Lymphadenia ossium, 363 Lymphadenitis, chronic, 304 hyperplastic, 336 Lymphadenoma, 336, 352 Lymphangiofibroma, 149 1 Lymphangioma, 228 1018 INDEX Lymphangioma caverno- sum, 229, 232 clinical forms, 230 cutis circumscripta, 231 cysticum, 232 cystoides, 229 development, 229 histological structure, 229 mesenteric, 232 of ovary, 234 of salivary glands, 715 origin, 230 retropefitoneal, 232 sacral cystic, 960 simple, 229, 230 tuberosum, 294 multiplex, 231, 314 Lymphangitis carcinoma- tosa, 297 prolifera, 297 Lymphatic invasion in can- cer of uterus, 539 in sarcoma, 80 permeation, metastasis from, 76 tuberculosis, 352 Lymphatics involved in can- cer of large intestine, 647 of breast involved in can- ! cer, 508 Lymphemia, lymph-nodes l in, 339 lymphoplastic, 339 Lymph-nodes enJothelioma of, 321 clinical types, 321 etiology, 325 frequency, 321 gross anatomy, 322 histogenesis, 324 localized, 321 metastases in, 322 structure, 322 systemic form, 321 in leukemia, 339 in lymphemia, 339 metastasis in, 77 Lymphocytoma, malignant, 368 Lymphocytosis in cancer, 68 Lymphogranuloma, 352. See also Granuloma, Hodg- kin's. Lymphogranulomatosis cu- tis, 356 Lymphoid tissue, tumors of, | 334 classification, 334 Lymphoid-cell leukemia, 348 Lymphoma, 27, 334 leukemic, 337 simple, 336 Lymphomatosis, aleukemic systemic, 362 Lymphomatous tumors of intestines, 255 tumors of stomach, 255 Lymphoplastic lymphemia, 339 Lymphosarcoma, 366 agressive qualities, 368 anatomic features, 366 clinical features, 366 subvarieties, 369 congenital, 375 cutaneous, 373 duration, 367 etiology, 374 extension, 367 extramedullary plasma- . cell, 374 histologic character, 369 metastases in, 372 of gastro-intestinal tract, 372 of intestine, 372 of kidney, 374 of lung, 796 of prostate, 767 of spleen, primary, 377 of stomach, 372 of testis, 373, 782 of thymus gland, 894 structure, 895 of tongue, 373 origin, 368 primary pharyngeal, 371 lesions, 368 regressive changes in, 368 relation of syphilis to, 241 of tuberculosis to, 241 retroperitoneal, 373 round- cell, large, 368 structure, 367, 372 tuberculosis in, 375 types, 368 MACROCHEILIA, 232 Macroglossia, 232 Macro melia, 232 Maladie de Reclus, 472 kystique, 468 noveuse, 472 Malignancy, diagnosis, 63 infiltrative growth in, 62 potential, clinical course and, differentiation, 64 significance of, 62 Malignant adenoma of thy- roid gland, 876 chordoma, 189 lymphocytoma, 368 neuroma, 415 tumors. See Cancer. Marantic type of cancer, 67 Marchand's atypical chori- oma, 555 Mastitis, chronic glandular, 472 cyst contents in, 472 development, 472 of benign or malig- nant process in, 474 Mastitis, chronic glandular, predisposition t o cancer in, 476 progress, 472 structure, 473 treatment, 476 interstitial, 471 productive, 468 etiology, 469 glandular, 469 interstitial, 469 senile, 469 cystic, 472 Maxillae, osteoma of, 194 Maxillary antrum, cancer of, 700 clinical course, 702 deformation stage, 702 invasion stage, 703 latent stage, 702 cysts of, 700 epithelial papilloma of, 700 tumors of, 699 tumors of dental origin, 686 Mediastinal dermoid cysts,. 946 lipoma, 179 tumors in Hodgkin's dis- ease, 355 Medullary cancer of breast, 5i3 of stomach, 615 tumors of adrenal gland, 749 chromafline cell, .754 with adrenalin con- tent and nephri- tic symptoms, 754 Medullocelles, 264 Meiostagmin reaction in cancer, 92 Melanin in melanoma, 859 Melanoma, 849 clinical characters, 849 course, 851 extensions, 855 histogenesis, 865 histology, 852 history, 849 malignant change in, 855 melanin in, 859 modes of origin, 854 of adrenal gland, 756, 868 of brain and cord, 863 of breast, 488 of glans penis, 847 of intestine, 864 of liver, 672 of meninges, diffuse, 422 of nares, 702 of rectum, 652 of uncertain origin, 865 orbital, 860 etiology, 863 INDEX 1019 Melanoma, orbital, structure, 862 pigmentation in, 857 Melanotic whitlow, 851 Meningeal pseudoneo- plasms, 426 Meninges, endothelioma of, 305 melanoma of, diffuse, 422 sarcoma of, 408, 420 diffuse, 408, 422 structure, 409 sarcomatosis of, diffuse, 421 multiple, 421 Meningitis arenosa, 306 serosa circumscripta, 426 Mesenteric cysts, 952 lymphangioma, 232 Mesobranchial d e r m o i d cysts, 944 Mesodermal t u m o r s of breast, 482 Mesentery, dermoid cysts of, 953 Mesonephric adenomyoma, 210 tumors, 590 Metastasis, 76 formation of, 62 from lymphatic permea- tion, 76 lymph-node, 77 of benign tumors, 84 preservation of structural type in, 86 pulmonary embolism from, 84 paradoxic, 84 secondary, 84 tertiary, 84 susceptibility of tissue to, 86 Metastatic sarcoma of spinal cord, 425 Microorganisms in cancer, 116 Mikulicz's disease, 356 Miliary carcinosis, 447 Mitosis in tumors, 38 Mixed tumors, 938 special forms, 942 Mixed-cell leukemia, 346 Mole, congenital, 852 nbromatous regression in, 854 pigmented, of adults, 853 Mollities ossium, 283 Molluscum contagiosum, 434 Monsters, double, 932 symmetrical, 932 Mouth, cancer of, epider- moid, 819 Mucoid cancer of breast, 495, 5i5 Mucous adenocarcinoma of cervix uteri, 529 degeneration in tumors, 44 Mulberry cells in tumors, 45 Muller's tailed corpuscles, 21 Multicentric growth of tu- mors, 36 Multiple lipoma, 176 symmetrical lipomas, 176 Mural sarcoma of uterus, 258 Muscle tissue tumors, 27 Muscles, angioma of, 220 sarcoma of, 253 Mycetozoa in cancer, 117 Myelogenous lipoma, 179 pseudoleukemia, 283 Myeloid pseudoleukemia, 365 Myeloma of bone, 283 albumosuria in, 285 classification, 289 clinical course, 285 erythroblastic origin, 289 etiology, 289 gross anatomy, 284 histogenesis, 287 structure, 285 of bone-marrow, multiple, 283 Myeloplacques, 264 Myofibroma, 178 Myolipoma of kidney, 213 Myoliposarcoma, 178 Myoma, 27, 199 malignum, 201 of alimentary tract, 212 of bladder, 212 of kidney, 213 of renal hilus, 745 of skin, 212 of stomach, 212 of testes, 212, 780 of urinary organs, 212 of uterus, 203 degenerative changes in, 206 etiology, 208 form, 204 gross appearance, 206 microscopic structure, 207 recurrent, 260 | Myosarcoma, 27 of gall-bladder, 676 of stomach, spindle-cell, 254 ! Myositis ossificans, 197 Myxochondrocarcinoma of salivary glands, 714 Myxo-endothelioma, 168 Myxofibroma, 166 Myxoglioma, 386 Myxolipoma, 166 , Myxoma, 27, 166 anatomical characters, 167 clinical forms, 169 course, 168 combined with lipoma, 172 Myxoma, congenital, of navel, 170 etioiogy, 172 fibromatosum of kidney, 161 intiacanalicular, of breast, 480 location, 169 matrix, 167 of bones, 170 of heart, 170 of nervous system, 169 of renal hilus, 745 origin, 171 primary, 166 structure, 167, 171 Myxosarcoma, 168 of ovary, 257 of renal hilus, 745 NARES, fibroma of, 162 melanoma of, 702 Nasal glioma, 395 polyp, 162 sinuses, tumors of, 699 Nayopharyngeal fibroma, ju- venile, 164 course, 165 Navel, congenital myxoma of, T7o | Necrotic tissue, osteoma of, 197 Negroes, predisposition to keloid, 158 Neoplastic hyperplasia, mor- phology, 41 versus inflammatory hyperplasia, 40 Nerve nevus, 157 Nerve-trunks, endothelioma of, 309 tumors of, 411 Nervous system, myxoma of, 169 osteoma in, 196 tumors, 27 Neurinoma, 155 Neurocytoma, 398 of adrenal gland, 750 clinical types, 753 Neuro-epithelioma, 27, 384, 390 retinae, 406 Neurofibroma, 149 acoustic, 416 cirsoides, 154 of spinal cord, multiple, 424 optic, 418 plexiform, 154 Netirofibro matosis, pig- mented, 153 visceral, 154 Neuroglioma of pineal gland, ependymal, 928 Neuroma, 27, 411 amyelinicum, 411 gangliona, 27, 749 1020 INDEX Neuroma, ganglionic, 411, 414 etiology, 416 malignant, 415 myelinicum, 411 plexiform, 411 traumatic, 411 Neuropathic papilloma, 157 Nevus, bathing-trunk type, r 851- Imeans, 157 nerve, 157 results of study of, 866 unius lateris, 157 vascular, 219 vasculosus mollusciformis, 220 vinosus, 219 Nipple, Paget's disease of, 805 Nodes, singer's, 826 Nuclear fluid in tumor-cells, 46 Nuclein in tumor-cells, 46 Nucleus, cystic degeneration of, in tumors, 47 fragmentation of, in tu- mors, 47 ODONTOMA, 696, 697 etiology, 698 modes of origin, 699 soft, 698 Omental cysts, 952 Oncology, general, 17 special, 149 Oophoroma folliculare, 583 Optic neurofibroma, 418 Orbit, angioma of, 226 endothelioma of, 309 melanoma of, 860 etiology, 863 structure, 862 osteoma of, 194 teratomas of, 947 Orbitonasal fissures, dermoid cysts of, 947 Organization, influence of, on cancer, 100 Organoid tumors, 48 Osteitis fibrosa, 282 Osteochondroma, multiple, 185 Osteochondromyxosarcoma of breast, 487 Osteochondrosarcoma, 183 Osteodystrophia juvenilis, 282 Osteo-endothelioma, 296 Osteogenic sarcoma, 265 course, 270 sclerosing, 270 Osteoma, 27, 191 heteroplastic, 192 hyperplastic, 192 in nervous system, 196 of antra, 194 of eye, 197 Osteoma of facial bones, 194 of frontal sinus, 195 of lung, reticulated, 196 of maxillae, 194 of necrotic tissue, 197 of orbit, 194 of penis, 197 of skin, 197 secondary, 195 terminology, 191 true, 194 Osteomalacia, senile, 283 Osteophyte, 192 Osteosarcoma, 28 Ovarium gyratum, 162 Ovary, adenocarcinoma of, cystic, 577 papillary serous, 569 pseudomucinous, 575 adenofibroma of, 577 adenoma of, 566 everted papillary, 577 solid, 576 superficial papillary, 577 testicular, 590 adenomyoma of, 590 adrenal tumors of, 741 angioma of, cavernous, 227 cancer of, 577. dermoids of, 593. See also Dermoid cysts 'of ovary. endothelioma of, 317 appearance, 318 clinical course, 318 diagnosis, 318 structure, 319 fibroma of, 162 fibrosarcoma mucocellu- lare carcinomatodes of, 583 lymphangioma of, 234 metastases in, in gastric cancer, 629 myxosarcoma of, 257 sarcoma of, 256 round-cell, 256 teratoma of, 593. See also Teratoma. tumors of, adrenal, 590 age in etiology, 586 etiology, 586 histogenesis, 586 origin, 588 PACHYDERMATOCELE, 156 Pachydermia, 156 laryngis, 830 Pachy meningitis cervicalis hypertrophica, 426 interna sarcomatosa, 409 Paget's disease of nipple, 805 origin, 807 structure, 805 Pancreas, adenoma of, 68 1 cancer of, 68 1. See also Cancer of pancreas. cystadenoma of, 681 sarcoma of, 685 tumors of, 681 Papillary adenocarcinoma of choroid plexus, 402 of corpus uteri, 534 of kidney, histogenesis, 725 structure, 727 with granular cells, 725 of ovary, serous, 569 adenoma, cystic, 438 of kidney, 718 of ovary, everted, 577 superficial, 577 cancer, 447, 453 _ of kidney with clear cells, 722 epithelial tumors of thy- roid gland, 877 structure, 878 epithelioma of lip, 816 epithelioma of renal pelvis and ureter, 742 fibroma, 149 intracystic fibro-adenoma of breast, 479 Papilloma, 27, 429 bronchial, 791 clinical course, 430 development of malig- nancy in, 431 form, 430 neuropathic, 157 of bladder, 838 allantoid type, 842 anatomy, 839 course, 839 structure, 841 of breast, 488 of large intestine, villous, 651 of larynx, 825 structure, 826 of maxillary antrum, epi- thelial, 700 of renal pelvis and ureter, 742 of tongue, 435 Paraffin cancer of scrotum, 848 Paranuclein in tumor-cells, 46 Parasites, scope of relation to cancer, 123 INDEX 1021 Parasitic fetus, 935 theory of cancer, 114 classification by, 126 theoretic objections, 121 Parathyroid gland, cysts of, 887 tumors of, 886 Parenchymatous goiter, 872 acquired, 873 Parosteal exostosis, 193 sarcoma, 270 Parotid gland, hemangioma of, 7i5 Parovarium, tumors of, 589 Pars intermedia of pituitary, tumors of, 915 Pearls, enamel, 697 epithelial, in acanthoma, 457 Peau d'orange, 471 Pelvis, connective tissue of dermoid cysts of, 954 lipoma of, 179 renal, sarcoma of, diffuse, 745 spinosa, 180 Penis epithelioma of, 844 course, 846 established disease, 845 extension, 845 initial lesion, 845 structure, 847 osteoma of, 197 tumors of, 844 Pentose in tumors, 89 Pepper's type of congenital sarcoma of adrenal gland and liver in infants, 753 Peptic ulcer, cancer follow- ing, 610 Peribronchial sarcoma of lung, 795 Periosteum, fibroma of, 160 sarcoma of, 265 Perirenal lipoma, 179 Perithelioma, 219, 295, 307, .327 clinical types, 330 gross appearance, 328 of bones, 330 of breast, 330 of cervix uteri, 530 of kidney, 330 ofparotid gland, 331 of pia mater, 330 structure, 329 Peritoneum, cysts of, 952 dermoid, 953 endothelioma of, 310 invasion of, in cancer of breast, 511 teratoid tumors of, 953 Perivascular endothelioma, 323 Petrified epithelioma, 799 Phagocytosis by tumor-cells, 47 Pharynx, dermoid cysts of, 947 lymphosarcoma of, pri- mary, 371 teratomas of, 948 Phosphorus in tumors, 89 Physaliden of Virchow, 44, 182 Pia mater, perithelioma of, 330 Pial glioma, 397 Pigmented mole of adults, 853 neurofibromatosis, 153 Pineal gland, 925 cysts of, 926 glioma of, ependymal, 927 general pathology, 925 histology, 925 neuroglioma of, ependy- mal, 928 teratoma of, 926 tumors of, 925 classification, 926 clinical features, 929 occurrence, 926 structure, 928 symptomatology, 928 , Pituitary gland, adenocarci- noma of, 909 metastases, 909 structure, 910 anatomy of, 902 angiosarcoma of, 911 cancer of, atypical, 911 functional changes in, .905 histology of, 904 hyperplasia of, diffuse, 907 natural course, 923 posterior lobe, glioma of, 916 lipoma of, 916 tumors of, 901, 907, 916 anatomy, 906 cephalic, 916 dystrophic, 917 etiology, 901 relation of type with symptom complex, 922 symptomatology, 916 glandules, accessory, anat- omy of, 904 Plasma-cell leukemia, 350 lymphosarcoma, extrame- dullary, 374 Plastin in tumor-cells, 46 Pleura, endothelioma of, 309 involvement of, in cancer of breast, 510 Plexiform angioma, 219 endothelioma, 296, 323 epithelioma, 458 neurofibroma, 154 neuroma, 411 Polarity, loss of, in cancer, 452 Polyp, choanal, 163 nasal, 162 Polyposis, intestinal, 652 cancer following, 641 Porphyry spleen, 354 Port- wine stain, 219 Posterior lobe of pituitary, glioma of, 916 lipoma of, 916 Post-generation of embryos, 934 Postnatal tumors, 26 Precancerous changes in cer- vix uteri, 530 in corpus uteri, 536 lesions, 458 stage of tumor growth, 34 Pregnancy, effect of, on uterine cancer, 540 Presarcomatous lesions, 241 Presternal dermoid cysts, 947 Prostate, adenocarcinoma of, 765 adenoma of, 764 cancer of, 759. epithelioma of, squamous, 766 hypertrophy of, 757 adenomatous, 442, 758 carcinomatous, 758 etiology, 758 productive inflamma- tion in, 757 structure, 757 lymphosarcoma of, 767 rhabdomyosarcoma of , 767 sarcoma of, 766 spindle-cell, 767 tumors of, 757 Proteins, tumor, constitution of, 89 febrile destruction of,'66 toxic destruction of, 66 Protozoa in cancer, 116 Psammoma, 296 endothelial, 315 of spinal cord, 423 Pseudo-adiposis in tumors, 47 Pseudoleukemia, 351 gastro-intestinal, 363 myelogenous, 283 myeloid, 365 true, 362 blood in, 362 clinical features, 362 general features, 362 histology, 362 Pseudomucinous adenocarci- noma of ovary, 575 adenoma of ovary, 566 cystadenoma of ^ovary, 57i 1022 INDEX Pseudomyxoma p e r i t o n e i, 447, 575 Pseudoneoplasms, m e n i n- geal, 426 Psoriasis preputialis, 845 Pulmonary embolism, meta- static, 84 paradoxic, 84 secondary, 84 tertiary, 84 Pulp tumors, 29 Pylorus, sclerosing fibrocar- cinoma of, 619 RADICULODENTAL cysts, 694 Rankenneurome, 154 Ransohoff's test in cancer, 93 Rat, experimental cancer of stomach in, 133 Rectum, melanoma of, 652 Recurrent myoma of uterus, 260 Regenerative hypertrophy, cancer from, 461 Regressive changes in tu- mor-cells, 43 Renaissance period, cancer in, 18 Renal hilus, lipoma of, 745 myoma of, 745 myxoma of, 745 myxosarcoma of, 745 sarcoma of, diffuse, 745 tumors of, 745 lipoma, 178 pelvis, alveolar cancer of, 744. epithelial tumors of, 742 papillary epithelioma of, 742 papilloma of, 742 sarcoma of, diffuse, 745 squamous-cell cancer of, 743 Replacement lipomatosis, 177 Respiratory tract, chon- droma of, 187 Reticulated epithelioma of skin, 808 osteoma of lung, 196 Reticulosplenome nodulaire, 377 Reticulum-cell sarcoma, 325, 368 Retina, glioma of, 405 etiology, 407 structure, 406 neuro-epithelioma of, 406 Retroperitoneal d e r m o i d cysts, 954 lymphangioma, 232 lymphosarcoma, 373 teratoids, 954 tumors of adrenal rests, lateral, 741 Rhabdomyoma, 27, 199, 213, 217 appearance, 213 clinical forms, 214 course, 214 of heart, congenital, 215 of testis, 216 of urinary bladder, 214 of uterus, 214 structure, 213 Rhabdomyosarcoma of pros- tate, 767 Rickets in etiology of chon- droma, 184 Riga's disease, 435 Rodent ulcer, 808 crateriform, 840 histogenesis, 8n structure, 840 Round-cell cancer of salivary glands, 706 lymphosarcoma, large, 368 sarcoma, 238 of bone, 276 of breast, 486 of lung, 795 of ovary, 256 SABER-SHEATH veins in tu- mors, 57 Sacral cystic lymphangioma, 960 hygroma, 233, 960 mixed tumors, congenital, I origin, 961 teratomas, 958 Sacrococcygeal d e r m o i d j cysts, 956 mixed tumors, 956 teratoids, 958 teratomas, 956 Salivary glands, adenocarci- noma of, 705 adenoma of, 704 cancer of, 704 round cell, 706 chondroma of, 188 cylindroma of, 705 epithelial tumors of, 704 lymphangioma of, 715 myxochondro c a r c i- noma of, 714 tumors of, mixed, 706 Sand tumors, 30, 296 Sarcoma, 27, 235 alveolare epit helioides, 321 anatomy, 235 botryoides, 214 characters of growth, 236 clinical types, 244 combined with endothe- lioma, 302 deciduocellulare, 546 epithelioides, 294 etiology, 240 fasciculatum, 245 fibrd'blastic, 244 Sarcoma, general character, 235 glioma and, differentia- tion, 392 Hodgkin's, 359 lamellosum, 245 lymphatic invasion by, 80 multiple hemorrhagic, 247 histologic structure, 248 of adrenal gland, in infants with cranial metastases (Hutchinson type), 753 of bladder, 844 of bone, 264 capsular, 270 classification, 265 duration, 277 of life in, 277 etiology, 280 giant-cell, 273 benign, 271 prognosis, 278 histologic varieties, 268 historical notes, 264 prognosis, 276 rapidity of growth, 277 round-cell, 276 spindle-cell, 272 prognosis, 279 structures, 272 telangiectatic, 268 prognosis, 278 trauma in, 280 of bone-marrow, 264 primary multiple, 283 of brain, malignancy, 410 and meninges, 408 diffuse, 408 gross anatomy, 408 structure, 409 of breast, pure, 485 round-cell, 486 spindle-cell, pure, 487 of esophagus, 253 of fascia, 244, 253 of gall-bladder, 676 of intestine, 255 spindle-cell, 255 of larynx, 834 of liver, 671 and adrenal in infants, congenital (Pepper's type), 753 of lung, 794 classification, 795 diffuse spindle-cell, 795 peribronchial, 795 round-cell, 795 of meninges, clinical course, 422 of muscles, 253 of ovary, 256 round-cell, 256 of pancreas, 685 of prostate, 766 of renal hilus and pelvis, diffuse, 745 INDEX 1023 Sarcoma of, skin, 247 of spinal cord, central, 423 and meninges, 420 metastatic, 425 solitary, 421 of spleen, 376 endothelial, 376 spindle-cell, 376 of stomach, 254, 255 of tendon-sheaths and aponeuroses, giant-cell, 251 of testis, 773, 780 of thymus, 898 of thyroid gland, 884 of uterine mucosa, 261 of uterus, 258 etiology, 261 histogenesis, 261 metastases in, 259 mural, 258 structure, 258, 259 osteogenic, 265 course, 270 parosteal, 270 periosteal, 265 radiare, 245 reticulum-cell, 325, 368 round-cell, 238 sclerosing osteogenic, 270 spindle-cell, 244. structure, 237 telangiectatic, 219 trabeculare, 245 Sarcomatoid structures in cancer of cervix uteri, 530 Sarcomatosis of meninges, diffuse, 421 multiple, 421 Sarcomatous struma, 911 Sarcome angiolithique, 424 angioplastique of testis, 775 Schimmelbusch's disease, 4/2 multiple cystadenoma, 469 Scirrhus cancer of breast, of cervix uteri, 529 of prostate, 766 of stomach, clinical fea- tures, 638 diffuse, 616 Eustuleux, 515 jrosing fibrocarcinoma of stomach, clinical fea- | tures, 638 osteogenic sarcoma, 270 pyloric fibrocarcinoma, 619 Scrotum, cancer of, 847 paraffin, 848 Sebaceous cysts of breast, 488 Secondary epithelioma, 328 osteoma, 195 Seminome, 773 Senile chronic mastitis, 469 involution of breasts, 470 osteomalacia, 283 Sennert's theory of cancer, 18 Serology of tumors, 89 Serous adenoma of ovary, 566 cavities, invasion of, by cancer, 80 cystadenoma of ovary, 566 cystoma of ovary, 563 cysts, 952 membranes, endothelioma of, 309 Singer's nodes, 826 Skeletal chondroma, 185 location, 181 Skin, acanthoma of, 797. See also Acanthoma of skin. angio-endothelioma of, 316 cysts of, atheromatous, 942 epithelial, 942 endothelioma of, 314 epithelioma of, adenoid, 813 adenoid simple, 814 basal-cell, 808 reticulated, 808 invasion in cancer of breast, 506 lesions in Hodgkin's dis- ease, 356 myoma of, 212 osteoma of, 197 sarcoma of, 247 spindle-cell sarcoma of, 249 etiology, 251 histogenesis, 250 structure, 249 Skull changes in brain tu- mor, 383 Spermatic cord, fibrolipoma of, 779 fibroma of, plexiform, 779 hypernephroma of, 742 Spina bifida occulta, 961 tumors associated with, 960 Spinal cord, angioma of, 424 degeneration of, in brain tumors, 383 glioma of, 395 lipoma of, 424 melanoma of, 863 neurofibroma of, mul- tiple, 424 psammoma of, 423 relation of tumors to, j • 427 sarcoma of, 420 central, 423 metastatic, 425 Spinal cord, sarcoma, of, soli- tary, 421 tuberculosis of, 426 tumors of, 419. See also Tumors of spinal cord. secondary changes in, 425 symptomatology, 426 xanthochromia in, 425 membranes, relation of tumors to, 427 Spindle-cell myosarcoma of stomach, 254 sarcoma, 244 blood-vessels of, 245 diagnosis, 245 histogenesis, 246 of bone, 272 prognosis, 279 of breast, pure, 487 of intestine, 255 of lung, diffuse, 795 of ovary, 256 of prostate, 767 of skin, 249 etiology, 251 histogenesis, 250 structure, 249 of spleen, 376 rate of growth, 244 secondary changes, 245 structure, 244 Spirochetas in cancer, 117 Spleen, lesions in, in leuke- mia, 340 lymphosarcoma of, pri- mary, 377 porphyry, 354 sarcoma of, 376 endothelial, 376 spindle-cell, 376 Splenic Hodgkin's disease, 354 Splenoma, 377 Splenomegaly, primary (Gaucher type), 304 Spontaneous cure in tumors, 60 Spotted kidney, 720 Squamous epithelioma of prostate, 766 Squamous-cell adenocarci- noma of corpus uteri, 534 cancer of choroid plexus, 403 of gall-bladder, 676 of large intestine, 652 of renal pelvis and ureter, 743 Stain, port- wine, 219 Stammler's reaction in can- cer, 93 Stenosing fibrocarcinoma of large intestine, 649 Stomach, adenocarcinoma of, 607 1024 INDEX Stomach, adenocarcinoma of , occurrence, 636 structure, 609 adenoma of, simple, 609 cancer of, 605. See also Cancer of stomach. endothelioma of, 320 fibrocarcinoma of, diffuse, 619 sclerosing, clinical fea- tures, 638 leather-bottle, in, linitis plastica, 624 lymphosarcoma of, 372 mucosa of, in cancer, 624 myoma of, 212 myosarcoma of, spindle- cell, 254 relation of lymphatics in cancer, 626 sarcoma of, 254, 255 tumors of, lymphomatous, 255 ulcerocancer of, 637 Stools, blood in, in cancer, 72 Stroma of tumors, 54 regressive changes in, 55 Struma adrenalis, 444 colloid, 444 hypophysis, 444 ovarii, 595, 601 postbranchialis, 879 sarcomatous, 911 suprarenalis, 178 Subcutaneous lipoma, 177 Sublingual dermoid cysts, Q44 Submaxillary gland, epithe- lial tumors of, 716 Submucous cavernoma, 226 Subperiosteal chondroma, 181 Sweat-glands, tumors of, 814 Symmetrical double mon- sters, 933 Syncytial endometritis, 555 wandering cells, 548 Syncytioma, 555 clinical course, 558 metastases in, 556 Synovial lipoma, 177 Syphilis, relation of, to lymphosarcoma, 241 Syringomyelia associated with gliosis, 397 Systemic aleukemic lympho- matosis, 362 TAIL, false, 961 Telangiectasis, 219 Telangiectatic sarcoma, 219 of bone, 268 prognosis, 278 Tendon-sheaths, giant-cell sarcoma of, 251 Teratoblastomas, 939^ Teratoid chondroma, 188 Teratoids, cervical, 945 ' Teratoids, intrarranial, 951 of breast, mixed, 482 of hypophyseal duct, 912 ol testis, 772 peritoneal, 953 retroperitoneal, 954 sacrococcygeal, 958 Teratology, 931 Teratoma, 28, 936 abdominal fetal, 953 autochthonous, 949 causes, 938 cervical, 945 classification, 938 intracranial, 951 morphogenesis, 937 of orbit, 947 of ovary, 593 anatomy, 593 atrophic bidermal, 599 clinical course, 593 contents, 595 dermoids and, differen- tiation, 595 etiobgy, 603 mesodermal elements in, 598 metastases, 598 prognosis, 593 relation to simple tumors, 602 with cystoma, 594 of pineal gland, 926 of testis, 768 adult, clinical course, 772 derivatives, 768 etiology, 782 historical note, 768 metastases, 778 relation to miscellane- ous tumors, 779 structure, 775 varieties, 768 pharyngeal, 948 sacral, 958 sacrococcygeal, 956 source, 937 special forms, 942 Teratomatous glioma, 398 Testicular adenoma of ovary, 590 Testis, adenoma of, 780 chondroma of, 779 embryoma of, adult, 768 endothelioma of, 298 fibroma of, 162, 779 hypernephroma of, 742 interstitial cells of, hyper- plasia of, 781 lymphosarcoma of, 373, 782 myoma of, 212, 780 rhabdomyoma of, 215 sarcoma of, 780 teratoma of, 768. See also Teratoma of testis. tumors of, 768 Testis, tumors of, adrenal, 781 embryoid, 772 embryonal, 773 miscellaneous, relation to teratoma, 779 mixed, 772' teratoid, 772 Thiersch's theory of cancer, 23 Thoracic duct, invasion of, by cancer, 79 Thymoma, 894 interpretation of, 898 structure, 895 Thymus gland, anatomy, 889 anlage of, 889 cancer of, 897 cysts of, 892 general pathology, 891 hypertrophy of, simple, 891 lymphosarcoma of, 894 structure, 895 sarcoma of, 898 tumors of, 889 classification, 894 clinical course, 900 primary, 893 Thyroglossal duct, dermoid cysts of, 946 Thyroid gland, adenocarci- noma of, 876 small alveolar large- cell, 879 adenoma of, fetal, 873 interacinous, 872 malignant, 876 cancer of, 879. See also Cancer of thyroid gland. cysts of, 887 hypertrophy of, con- genital, 442 normal, metastases from, 882 sarcoma of, 884 tumors of, 869 papillary epithelial, 877 structure, 878 Tibia, adamantinoma of, 694 Tissue tension theory of cancer, 98 Tongue, angioma of, caver- nous, 226 cancer of, epidermoid, 819 lymphosarcoma of, 373 papilloma of, 435 Trachea, exostosis of, 193 Transplantable tumors, 136 adaptation of, 140 fate of, 139 nature and origin, 136 Transplantation of tumors, 127, 134 INDEX 1025 Transplantation of tumors, acquired resistance to, 144 between animals of dif- ferent species, 134 between lower animals of same species, 135 between man and man, between related species of lower animals, 135 hypersusceptibility to, 147 influence of variations in soil, 141 natural resistance to, 144 nature of factors in resistance, 145 passive resistance to, 145 Transplanted tumors, in- j fluence of diet on, 141 | resistance to, 143 spontaneous absorption, \ 141 structural changes in, , 142 Trauma in etiology of tu- | mors, 109, no frequency, 112 medicolegal aspects, 112 mechanism, in Traumatic exostoses, 193 neuroma, 411 tumors, 26 Tryptophan in tumors, 90 Tuberculosis, Hodgkin's dis- ease and, 360 in lymphosarcoma, 375 lymphatic, 352 of spinal cord, 426 relation of, to lympho- sarcoma, 241 Tubo-ovarian cysts, 564 Tubular acanthoma of skin, 798 adenocarcinoma of kid- ney, 729, 73i adenoma, 438 of kidney, 719 cancer of kidney, 729 structure, 731 Tumeur a medullocelles, 264 ' Tumeur a myeloplacques, 264 Tumor-cells amphipyrenin in, 46 anaplasia of, 101 desmoplastic, 54 fertilized, 102 linin in, 46 nuclear fluid in, 46 nuclein in, 46 paranuclein in, 46 peculiarities of, 46 phagocytosis by, 47 plastin in, 46 65 Tumor-cells, rapid and pro- gressive multiplication of, 59 regressive changes in, 43 relation to sex-cells, 102 Tumors, 25 adrenal, of female genital organs, 741 adrenal rest, 734 carcinomatous, 738 gross appearance, 736 lateral retroperito- neal, 741 occurrence, 735 peritheliomatous, 738 renal tumors and, dif- ferentiation, 739 sarcomatous, 738 structure, 737 trabecular, 738 adult, 26, 49 amitosis in, 39 anaplasia in, 39 associated with spina bi- fida, 960 asymmetric mitosis in, 39 autogenous antigen, com- plement deviation with, 9T benign, metastasis of, 84 malignant transforma- tion in, 461 blood-vessel lesions in, 57 cell division in, 38 central growth in, 3 1 chemistry of, 8,9 classification, 26 collateral hypertrophy in, 37 colloid degeneration in, 46 color of tissue, 29 complex tissue type, 28 congenital sacral mixed, origin, 961 connective tissue type, 27 consistence, 30- course, 59 cystic degeneration o f nucleus in, 47 of carcinomatous struc- ture, 447 cysts in, 34 definition, 25 effects on body, 65 emaciation from, 65 embryologic classification, 28 embryonal, 26, 49 endothelial type, 27 epithelial type, 27 etiological classification, 26 expansive growth, 25 experimental production of, 127 by .v-ray, 132 chronic inflammation in, 131 Tumors, experimental study, 119 extensive growth, 25 fats in, 90 fatty degeneration in, 43 febrile destruction of pro- tein in, 66 ferments in, 67, 90 heterolytic action, 67 fragmentation of nucleus in, 47 from chemical agents, 120 functional activity in, 53 gametoid mitosis in, 39 general morphology, 29 geotropism in, 53 glycogenic degeneration of, 44 growth, 31, 48 hereditary, 26 heterologous, 28, 49 heterotypic, 49 histioid, 28, 48 histological classification, 27 histopathology, 34 homologous, 28, 49 homotypic, 49 human, effects of injection of extract into animals, 132 hyaline changes in, 45 hydropic degeneration in, 43 infiltrative growth, 25, 31 influence of mechanical pressure in, 98 irritation group, 458 lactic acid in, 89 liquefaction cysts in, 32 local circumscription of, 29 lutein-cell, 565 malignant change in, 461 malignancy in, significance of, 62 maxillary, of dental 'oririn, 686 mesonephric, 590 mitosis in, 38 mixed, 739 special forms, 942 modes of origin, 36 mucous degeneration in, 44 mulberry cells in, 45 multicentric growth of, 36 muscle tissue type, 27 natural limitations of growth in, 40 limits to, 59 nervous system type, 27 nomenclature, 26 of adrenal gland, 746 classification, 746 medullary, 749 chromaffine cell, 754 1026 INDEX Tumors of adrenal gland, medullary, with adre- nalin content and ne- phritic symptoms, 754 tissue of kidney, 734 of antrum of Highmore, 699 of Bartholin's gland, 544 of bile-ducts, 667, 668 of bladder, 844 epithelial, 838 of brain, 378 age incidence, 378 anatomical classifica- tion, 383 choked disc in, 383 circulatory disturbances in, 383 destruction of tissue in, 382 duration, 381 edema in, 382 general distribution, 380 meningeal complica- tions, 383 occurrence, 378 operability, 380 relative frequency, 379 secondary effects, 381 sex in, 378 skull changes in, 383 spinal cord degenera- tion in, 383 trauma in etiology, 378 of breast, 488 ectodermal mixed, 483 epithelial, 467 mesodermal, 482 mixed, 477 teratoid mixed, 482 of choroid plexus and ependyma, 400 etiology, 400 gross appearance, 401 structure, 402 of congenital origin, 26 of epithelium, general pa- thology, 429 of epoophoron, 589 of extrarenal adrenal rests, 740 of Fallopian tube, 592 of Gasserian ganglion, 418 of hypophyseal duct, 912 of infundibular ependyma, 405 of intestine, lymphoma- tous, 255 multiple, benign, em- bryonal, carcinoid, 642 of kidney, 717 adrenal tumors and, dif- ferentiation, 739 epithelial, 717 classification, 718 Tumors of lachrymal gland, 309, 704 of larynx, 825 benign, 827 of liver, 654 classification, 654 primary epithelial, 657 anatomical varie- ties, 660 clinical course, 659 varieties, 660 etiology, 657 histogenesis, 658 metastases, 659 relation to cirrho- sis, 657 of lung, 785 of lymphoid tissue, 334 classification, 334 of maxillary and nasal sinuses, 699 of ovary, adrenal, 590 age in etiology, 586 etiology, 586 histogenesis, 586 origin, 588 simple, relation to tera- toma, 602 of pancreas, 68 1 of parathyroid gland, 886 of parovarium, 589 of pars intermedia, of pituitary, 915 of penis, 844 of pineal gland, 925 classification, 926 clinical features, 929 occurrence, 926 structure, 928 symptomatology, 928 of pituitary gland, 901, 907, 916 anatomy, 906 cephalic, 916 dystrophic, 917 etiology, 901 relation of type with symptom -complex, 922 symptomatology, 916 of postnatal origin, 26 of prostate, 757 of renal hilus, 745 pelvis and ureter, epi- thelial, 442 of salivary glands, epi- thelial, 704 etiology, 712 mixed, 706 clinical course, 712 gross anatomy, 713 theories of origin, 706 structure, 714 of spinal cord and mem- branes, 419 age incidence, 420 classification, 420 Tumors of spinal cord and membranes, etiol- ogy, 419 duration, 428 extramedullary, 427 intramedullary, 427 level of, 426 relation of, to cord, membranes, and vertebras, 427 secondary changes in, 425 symptomatology, 426 vertebral, 427 xanthochromia in, 425 of stomach, lymphoma- tous, 255 of submaxillary gland, epi- thelial, 716 of sweat-glands, 814 of testis, 768 adrenal, 781 embryoid, 772 embryonal, 772 miscellaneous, relation to teratoma, 779 mixed, 772 teratoid, 772 of thymus gland, 889 classification, 894 clinical course, 900 primary, 893 of thyroid gland, 869 epithelial papillary, 877 structure, 878 of vulva, epithelial, 542 organoid, 48 parasitic theory of, classi- fication by, 126 pentose in, 89 peripheral growth in, 31 phosphorus in, 89 precancerous stage, 34 progressive growth, 25 proteins of, constitution, 89 pseudo-adipose in, 47 pulp, 29 rate of growth, 59 recurrence, 86 regional classification, 26 relation of blood-vessels to, 56 retrograde transport of, 83 saber-sheath veins in, 57 sacrococcygeal, mixed, 956 sand, 30, 296 serology of, 89 simple mixed, 28 special etiology, 109 specific causes, 26 spontaneous cure in, 60 regression in, 40 stroma of, 54 reactions in, 55 regressive changes in, 55 INDEX 1027 Tumors, structure, 48 teratoid. toxic destruction of pro- teins in, 66 transplantable, 136 adaptation of, 140 fate of, 139 ] nature and origin, 136 transplantation of, 127, 134 acquired resistance to, 144 between animals of dif- ferent species, 134 between lower animals of same species, 135 between man and man, 135 between related species of lower animals, 135 hypersusceptibility to, 147 influence of variations in soil, 141 natural resistance, 144 nature of factors in resistance, 145 passive resistance to, 145 transplanted, influence of diet on, 141 resistance to, 143 spontaneous absorption, 141 structural changes in, 142 trauma in etiology, 26, 109, no frequency, 112 mechanism, in medicolegal aspects, 112 tryptophan in, 90 typical mitosis in, 38 ulceration in, 33 unicentric growth of, 36 ULCER, peptic, cancer fol- lowing, 610 rodent, 808 crateriform, 840 Ulcer, rodent, histogenesis, 8n structure, 840 Ulceration in tumors, 33 Ulcerative infiltrating epi- thelioma of lip, 816 Ulcerocancer of stomach, 63 7 Unicentric growth of tumors, 36 Urea, percentage of, in cancer, 72 Ureter, cancer of, alveolar, 744 primary, 843 squamous cell, 743 epithelioma of, papillary, 742 papilloma of, 742 tumors of, epithelial, 742 Urethra, cancer of, 847 Uric acid increase in cancer, 72 Urinary bladder, rhabdomy- oma of, 214 organs, myoma of, 212 Urine, changes in, in cancer, 72 Urobilin in cancer, 74 Uterus, adeno-acanthoma of, 527 adenomyoma of, 207 adrenal tumors of, 741 cancer of, 523. See also j Cancer of uterus, carcinosarcoma of, 262 chondroma of, 188 endothelioma of, 320 fibromyoma of, 203 lipoma of, 179 mucosa of, sarcoma of, 261 myoma of, degenerative changes in, 206 etiology, 208 form, 204 gross appearance, 206 microscopic structure, 207 recurrent, 260 rhabdomyoma of, 214 sarcoma of, 258. See also Sarcoma of uterus. VAGINA, epidermoid cancer of, 544 Varicosities, chronic, 219 Vascular nevus, 219 Vater, ampulla of, cancer of, 679 Verruca plana juvenilis, 431 vulgaris, 431 Vertebrae, relation of spinal tumors to, 427 Vertebral tumors of spinal cord, 427 Villous papilloma of large intestine, 651 Virchow's physaliden, 44, 182 theory of cancer, 22 Visceral neurofibromatosis, Vulva, epidermoid cancer of, 542 epithelial tumors of, 642 WANDERING cells, syncytial, 548 Warts, cutaneous, 431 Wassermann reaction in can- cer, 91 Whitlow, melanotic, 851 XANTHELASMA, 159 Xanthochromia in spinal cord tumors, 425 Xanthoma, 159 diabeticorum, 159 generalized, 159 multiplex, 159 palpebrarum, 159 planum, 159 structure, 160 tuberosum, 159 vulgare, 159 Xanthomatosis, 160 Xeroderma pigmentosum, 80 1 X-ra,y dermatitis, cancer and, 802 clinical course, 802 structure, 803 experimental production of tumors by, 132 RETURN TO the circulation desk of any University of California Library or to the NORTHERN REGIONAL LIBRARY FACILITY Bldg. 400, Richmond Field Station University of California Richmond, CA 94804-4698 ALL BOOKS MAY BE RECALLED AFTER 7 DAYS • 2-month loans may be renewed by calling (510)642-6753 • 1-year loans may be recharged by bringing books to NRLF • Renewals and recharges may be made 4 days prior to due date DUE AS STAMPED BELOW MAR 2 0 2007 lJUL 05 2007 DD20 12M 1-05 F; UNIVERSITY OF CALIFORNIA LIBRARY. 