Supplementary Figure 4 from Mammalian Target of Rapamycin Activator RHEB Is Frequently Overexpressed in Human Carcinomas and Is Critical and Sufficient for Skin Epithelial Carcinogenesis
Supplemental Figure 4, Lu et al. Supplemental Figure 4, Lu et al. Supplemental Figure 4, Lu et al. Rheb
WT
A
Rheb
WT
B Supplemental Figure 4, Lu et al. Rheb
WT
A
Rheb
WT
C
WT
Rheb
B
D
80
100
a- A Rheb
WT
A Rheb
WT
Rheb
WT
C
WT
Rheb
B
D
0
5
10
15
20
25
30
35
40
0
20
40
60
80
100
Age (week)
Percent Papilloma-
bearing mice (%)
K14-Rheb, N=42
Wild-type, N=36 Rheb
WT
B B C
WT
Rheb C D
0
5
10
15
20
25
30
35
40
0
20
40
60
80
100
Age (week)
Percent Papilloma-
bearing mice (%)
K14-Rheb, N=42
Wild-type, N=36 D D