Is it more efficient to parse external XML or to hit the database?
It sounds like you essentially want to cache results, and are wondering if it's worth it. But if so, I would NOT use a database (I assume you are thinking of a relational DB): RDBMSs are not good for caching; even though many use them. You don't need persistence nor ACID.
If choice was between Oracle/MySQL and external web service, I would start with just using service.
Instead, consider real caching systems; local or not (memcache, simple in-memory caches etc).
Or if you must use a DB, use key/value store, BDB works well. Store response message in its serialized form (XML), try to fetch from cache, if not, from service, parse. Or if there's a convenient and more compact serialization, store and fetch that.
I was wondering when dealing with a web service API that returns XML, whether it's better (faster) to just call the external service each time and parse the XML (using ElementTree) for display on your site or to save the records into the database (after parsing it once or however many times you need to each day) and make database calls instead for that same information.