Apache mod_wsgi and python 2.7
To answer the specific question, no it is not possible to make a mod_wsgi installation compiled for one Python version to use a different version at run time.
Why don't you create a separate question for the actual problem you are having with compiling from source code. Better still ask it on the mod_wsgi mailing list where best people to help you can be found.
My WSGI installation uses python2.6 and my django project requires python 2.7 to work properly. Is is possible to relink the python version WSGI uses without recompiling wsgi? I've been having some odd errors trying to compile wsgi and I'd prefer to sidestep that whole troubleshooting process if possible. 
Thanks