Python quit unexpectedly while running Django
It looks like its the mysql-extension that crashes, if you have XCode you can try to make sure you have the latest one compiled locally and installed.
I'm running Python 2.7.1 on 64-bit Mac OSX Lion. Python keeps crashing while I'm running my local Django 1.3 development server. The error log is below. 
This is starting to get annoying. Any ideas?

Process:         Python [22917] Path:
  /System/Library/Frameworks/Python.framework/Versions/2.7/Resources/Python.app/Contents/MacOS/Python
  Identifier:      Python Version:         ??? (???) Code Type:
  X86-64 (Native) Parent Process:  Python [22635]
Date/Time:       2011-10-12 15:01:21.968 -0500 OS Version:      Mac OS
  X 10.7.1 (11B26) Report Version:  9
Interval Since Last Report:          293584 sec Crashes Since Last
  Report:           6 Per-App Crashes Since Last Report:   5 Anonymous
  UUID:                      AF6F3F62-2520-45F9-AD9C-B5D08053AE23
Crashed Thread:  1
Exception Type:  EXC_BAD_ACCESS (SIGSEGV) Exception Codes:
  KERN_INVALID_ADDRESS at 0x0000000000000058
VM Regions Near 0x58:
  --> 
      __TEXT                 0000000101d94000-0000000101d95000 [    4K] r-x/rwx SM=COW 
  /System/Library/Frameworks/Python.framework/Versions/2.7/Resources/Python.app/Contents/MacOS/Python
Application Specific Information: objc[22917]: garbage collection is
  OFF
Thread 0:: Dispatch queue: com.apple.main-thread 0
  libsystem_kernel.dylib            0x00007fff91c41386 close + 10 1
  libmysqlclient.18.dylib           0x00000001028330dc vio_close + 60 2
  libmysqlclient.18.dylib           0x00000001028329db vio_delete + 33 3
  libmysqlclient.18.dylib           0x0000000102818069 end_server + 50 4
  libmysqlclient.18.dylib           0x0000000102818174 mysql_close + 101 5 
  _mysql.so                         0x00000001028006a3 _mysql_ConnectionObject_close + 65 6   _mysql.so                         0x0000000102802274 _mysql_ConnectionObject_dealloc + 39 7
  org.python.python                 0x0000000101df1a85 0x101d9d000 + 346757
  8   org.python.python                 0x0000000101dd1caa 0x101d9d000 +
  216234 9   org.python.python              0x0000000101dd473a
  PyDict_DelItem + 186 10  org.python.python
    0x0000000101e5255c 0x101d9d000 + 742748 11  org.python.python
    0x0000000101da4d32 PyObject_Call + 97 12  org.python.python
    0x0000000101da4eed PyObject_CallFunctionObjArgs + 178 13 
  org.python.python                 0x0000000101df5818 0x101d9d000 + 362520
  14  org.python.python                 0x0000000101df5946
  PyObject_ClearWeakRefs + 246 15  org.python.python
    0x0000000101e51b61 0x101d9d000 + 740193 16  org.python.python
    0x0000000101dd1caa 0x101d9d000 + 216234 17  org.python.python
    0x0000000101e3e235 PyThreadState_Clear + 129 18  org.python.python
    0x0000000101e3e44c PyInterpreterState_Clear + 41 19 
  org.python.python                 0x0000000101e3fb7f Py_Finalize + 344 20
  org.python.python                 0x0000000101e3fd90 0x101d9d000 + 667024
  21  org.python.python                 0x0000000101e3fdc7 PyErr_PrintEx +
  41 22  org.python.python              0x0000000101e403f4
  PyRun_SimpleFileExFlags + 730 23  org.python.python
    0x0000000101e502af Py_Main + 2715 24  org.python.python
    0x0000000101d94e88 0x101d94000 + 3720
Thread 1 Crashed: 0   org.python.python
    0x0000000101e270dc PyEval_EvalFrameEx + 22922 1   org.python.python
    0x0000000101e27cd8 PyEval_EvalCodeEx + 1996 2   org.python.python
    0x0000000101e27e6c 0x101d9d000 + 568940 3   org.python.python
    0x0000000101e24e0a PyEval_EvalFrameEx + 14008 4   org.python.python
    0x0000000101e27cd8 PyEval_EvalCodeEx + 1996 5   org.python.python
    0x0000000101e27e6c 0x101d9d000 + 568940 6   org.python.python
    0x0000000101e24e0a PyEval_EvalFrameEx + 14008 7   org.python.python
    0x0000000101e27cd8 PyEval_EvalCodeEx + 1996 8   org.python.python
    0x0000000101dc5abf 0x101d9d000 + 166591 9   org.python.python
    0x0000000101da4d32 PyObject_Call + 97 10  org.python.python
    0x0000000101db36e9 0x101d9d000 + 91881 11  org.python.python
    0x0000000101da4d32 PyObject_Call + 97 12  org.python.python
    0x0000000101e20c40 PyEval_CallObjectWithKeywords + 180 13 
  org.python.python                 0x0000000101e5240d 0x101d9d000 + 742413
  14  libsystem_c.dylib                 0x00007fff8dfcb8bf _pthread_start +
  335 15  libsystem_c.dylib                 0x00007fff8dfceb75 thread_start
  + 13
Thread 2: 0   libsystem_kernel.dylib          0x00007fff91c40df2
  __select + 10 1   time.so                         0x00000001021ae030 0x1021ad000 + 4144 2   org.python.python
    0x0000000101e24d77 PyEval_EvalFrameEx + 13861 3   org.python.python
    0x0000000101e27cd8 PyEval_EvalCodeEx + 1996 4   org.python.python
    0x0000000101e27e6c 0x101d9d000 + 568940 5   org.python.python
    0x0000000101e24e0a PyEval_EvalFrameEx + 14008 6   org.python.python
    0x0000000101e27df7 0x101d9d000 + 568823 7   org.python.python
    0x0000000101e24e0a PyEval_EvalFrameEx + 14008 8   org.python.python
    0x0000000101e27cd8 PyEval_EvalCodeEx + 1996 9   org.python.python
    0x0000000101dc5abf 0x101d9d000 + 166591 10  org.python.python
    0x0000000101da4d32 PyObject_Call + 97 11  org.python.python
    0x0000000101db36e9 0x101d9d000 + 91881 12  org.python.python
    0x0000000101da4d32 PyObject_Call + 97 13  org.python.python
    0x0000000101e20c40 PyEval_CallObjectWithKeywords + 180 14 
  org.python.python                 0x0000000101e5240d 0x101d9d000 + 742413
  15  libsystem_c.dylib                 0x00007fff8dfcb8bf _pthread_start +
  335 16  libsystem_c.dylib                 0x00007fff8dfceb75 thread_start
  + 13
Thread 1 crashed with X86 Thread State (64-bit):   rax:
  0x00007fab51368e10  rbx: 0x0000000000000000  rcx: 0x00007fab5146dc90 
  rdx: 0x0000000101ecd670   rdi: 0x00007fab5146de28  rsi:
  0x0000000000000009  rbp: 0x0000000102dae630  rsp: 0x0000000102dae4c0
  r8: 0x00007fff784a50b0   r9: 0x0000000102dae458  r10:
  0x0000000000000081  r11: 0x0000000102c23064   r12: 0x00007fab51368e10 
  r13: 0x0000000103023f90  r14: 0x000000000000007c  r15:
  0x00000001023c4ddb   rip: 0x0000000101e270dc  rfl: 0x0000000000010246 
  cr2: 0x0000000000000058 Logical CPU: 2
Binary Images:
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         0x101d9d000 -        0x101eb8ff7  org.python.python (2.7.1 - 2.7.1)  /System/Library/Frameworks/Python.framework/Versions/2.7/Python
         0x1020ea000 -        0x1020edfff  strop.so (??? - ???) 
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         0x1020f2000 -        0x1020f5fff  operator.so (??? - ???) <59A152D0-52ED-354C-9C2D-D7390E3EC216>
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         0x10218f000 -        0x102195ff7  _socket.so (??? - ???) 
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         0x1021a7000 -        0x1021a8fff  cStringIO.so (??? - ???) 
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         0x1021ad000 -        0x1021aefff  time.so (??? - ???) 
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         0x1021b5000 -        0x1021b8fff  _collections.so (??? - ???) <62C1B5B7-654D-397A-8840-7EBB907DBCA1>
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         0x1021cd000 -        0x1021cdfff  _bisect.so (??? - ???) 
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         0x1021d1000 -        0x1021d2fff  _heapq.so (??? - ???) 
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         0x10221d000 -        0x10221dfff  _scproxy.so (??? - ???) 
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         0x102221000 -        0x10222cff7  datetime.so (??? - ???) <9EC1E3BD-3BD3-3B39-AE19-448CCEEA747A>
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         0x102322000 -        0x102327fff  math.so (??? - ???) 
  /System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/lib-dynload/math.so
         0x1023ad000 -        0x1023aefff  _hashlib.so (??? - ???) 
  /System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/lib-dynload/_hashlib.so
         0x1023b2000 -        0x1023b3ff7  _random.so (??? - ???) <3C7A7C17-1698-32D0-BF09-F50A19F75E4B>
  /System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/lib-dynload/_random.so
         0x102437000 -        0x102443fff  cPickle.so (??? - ???) 
  /System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/lib-dynload/cPickle.so
         0x102449000 -        0x10244bfff  select.so (??? - ???) 
  /System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/lib-dynload/select.so
         0x1024d1000 -        0x1024d2fff  fcntl.so (??? - ???) 
  /System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/lib-dynload/fcntl.so
         0x102596000 -        0x10259bfff  array.so (??? - ???) <177F1D09-ACEE-3E39-8F1E-3EE8BA8A7AC6>
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         0x102661000 -        0x102661fff  grp.so (??? - ???) <563EC9A6-F38F-3518-9BBB-912E9F01FDA1>
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         0x1026a5000 -        0x1026a6fff  termios.so (??? - ???) <578DA44F-17E3-3343-982F-BB543CBB49F1>
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         0x10276b000 -        0x10276dfff  zlib.so (??? - ???) <81E54FCE-EEAC-3E97-BB05-1143EB6AECA6>
  /System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/lib-dynload/zlib.so
         0x1027b2000 -        0x1027b8fff  pyexpat.so (??? - ???) <0E02E7DD-AC97-38B5-BB3B-856249DEBFF9>
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         0x1027ff000 -        0x102804fff +_mysql.so (??? - ???) <8B1F4F4C-09C5-33DC-9DA4-D611FF9E2AF4> /Users/USER/*/_mysql.so
         0x102810000 -        0x102aa0ff7  libmysqlclient.18.dylib (18.0.0 - compatibility 18.0.0) <6A688A2F-6420-D89A-A3BD-5F9605F6C4C2>
  /usr/lib/libmysqlclient.18.dylib
         0x102e31000 -        0x102e42fff  _io.so (??? - ???) <5451CA4B-98A0-3F70-9322-DBE6B7D93CF1>
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         0x102e51000 -        0x102e5dff7 +parser.so (??? - ???) <9384AA00-C2F8-3407-94F6-210FA55AFD70>
  /Library/Python/2.7/site-packages/http_parser/parser.so
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         0x102f8a000 -        0x102f8efff  _json.so (??? - ???) 
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      0x7fff88a3b000 -     0x7fff88a3cfff  libDiagnosticMessagesClient.dylib (??? - ???)
  <3DCF577B-F126-302B-BCE2-4DB9A95B8598>
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  /usr/lib/libz.1.dylib
      0x7fff939e7000 -     0x7fff939e8fff  libffi.dylib (??? - ???)  /usr/lib/libffi.dylib
External Modification Summary:   Calls made by other processes
  targeting this process:
      task_for_pid: 0
      thread_create: 0
      thread_set_state: 0   Calls made by this process:
      task_for_pid: 0
      thread_create: 0
      thread_set_state: 0   Calls made by all processes on this machine:
      task_for_pid: 206162
      thread_create: 1
      thread_set_state: 0
VM Region Summary: ReadOnly portion of Libraries: Total=62.8M
  resident=27.3M(43%) swapped_out_or_unallocated=35.5M(57%) Writable
  regions: Total=62.7M written=16.7M(27%) resident=22.3M(35%)
  swapped_out=0K(0%) unallocated=40.5M(65%)   REGION TYPE
  VIRTUAL
  ===========                      ======= MALLOC                             53.2M MALLOC guard page                    32K STACK GUARD                        56.0M Stack                              9232K VM_ALLOCATE                           8K
  __DATA                             2320K
  __LINKEDIT                         48.2M
  __TEXT                             14.6M
  __UNICODE                           544K shared memory                        12K
  ===========                      ======= TOTAL                             183.8M
Model: MacBookPro8,1, BootROM MBP81.0047.B0E, 2 processors, Intel Core
  i7, 2.7 GHz, 8 GB, SMC 1.68f96 Graphics: Intel HD Graphics 3000, Intel
  HD Graphics 3000, Built-In, 512 MB Memory Module: BANK 0/DIMM0, 4 GB,
  DDR3, 1333 MHz, 0x80CE, 0x4D34373142353237334448302D4348392020 Memory
  Module: BANK 1/DIMM0, 4 GB, DDR3, 1333 MHz, 0x80CE,
  0x4D34373142353237334448302D4348392020 AirPort:
  spairport_wireless_card_type_airport_extreme (0x14E4, 0xD6), Broadcom
  BCM43xx 1.0 (5.100.98.75.10) Bluetooth: Version 2.5.0f17, 2 service,
  19 devices, 1 incoming serial ports Network Service: AirPort, AirPort,
  en1 Serial ATA Device: APPLE SSD TS128C, 121.33 GB Serial ATA Device:
  OPTIARC DVD RW AD-5970H USB Device: hub_device, 0x0424  (SMSC),
  0x2513, 0xfa100000 / 3 USB Device: BRCM2070 Hub, 0x0a5c  (Broadcom
  Corp.), 0x4500, 0xfa110000 / 5 USB Device: Bluetooth USB Host
  Controller, apple_vendor_id, 0x821a, 0xfa113000 / 8 USB Device: Apple
  Internal Keyboard / Trackpad, apple_vendor_id, 0x0245, 0xfa120000 / 4
  USB Device: FaceTime HD Camera (Built-in), apple_vendor_id, 0x8509,
  0xfa200000 / 2 USB Device: hub_device, 0x0424  (SMSC), 0x2513,
  0xfd100000 / 2 USB Device: My Passport 0730, 0x1058  (Western Digital
  Technologies, Inc.), 0x0730, 0xfd120000 / 4 USB Device: IR Receiver,
  apple_vendor_id, 0x8242, 0xfd110000 / 3