Django -vs- Grails -vs-?
You asked for someone who used both Grails and Django. I've done work on both for big projects. Here's my Thoughts:
IDE's:
Django works really well in Eclipse, Grails works really well in IntelliJ Idea.
Debugging:
Practically the same (assuming you use IntelliJ for Grails, and Eclipse for Python). Step debugging, inspecting variables, etc... never need a print statement for either. Sometimes django error messages can be useless but Grails error messages are usually pretty lengthy and hard to parse through.
Time to run a unit test:
django: 2 seconds.
Grails: 20 seconds (the tests themselves both run in a fraction of a second, it's the part about loading the framework to run them that takes the rest... as you can see, Grails is frustratingly slow to load).
Deployment:
Django: copy & paste one file into an apache config, and to redeploy, just change the code and reload apache.
Grails: create a .war file, deploy it on tomcat, rinse and repeat to redeploy.
Programming languages:
Groovy is TOTALLY awesome. I love it, more so than Python. But I certainly have no complaints. 
Plugins:
Grails: lots of broken plugins (and can use every java lib ever).
Django: a few stable plugins, but enough to do most of what you need.
Database:
Django: schema migrations using South, and generally intuitive relations.
Grails: no schema migrations, and by default it deletes the database on startup... WTF
Usage:
Django: startups (especially in the Gov 2.0 space), independent web dev shops.
Grails: enterprise
Hope that helps!
I'm wondering if there's such a thing as Django-like ease of web app development combined with good deployment, debugging and other tools? 
Django is a very productive framework for building content-heavy sites; the best I've tried and a breath of fresh air compared to some of the Java monstrosities out there. However it's written in Python which means there's little real support in the way of deployment/packaging, debugging, profilers and other tools that make building and maintaining applications much easier. 
Ruby has similar issues and although I do like Ruby much better than I like Python, I get the impression that Rails is roughly in the same boat at Django when it comes to managing/supporting the app. 
Has anyone here tried both Django and Grails (or other web frameworks) for non-trivial projects? How did they compare?