ISO-8859-1 Not working on IE
Yes, it is better to use UTF-8 instead.
Your question really cannot be answered unless you also provide the bytes that you are sending.
I am working on some programs in spanish, so I need to use accent marks. This is why I use 
 # -*- coding: iso-8859-1 -*- and <meta http-equiv="Content-Type" content="text/html; charset=ISO-8859-1"> on all my programs (python). I tested in chrome,firefox and safari and they all work puttin the accent marks. The only one that does not work is IE8. It does not apply the accent mark, and add some other character instead.
Does anyone know if there is a problem with IE8?
Is it better to use UTF-8 instead?