Django with PyPy
Depends.
PyPy does improve performance for all benchmarks that are in the PyPy's benchmark suite. This is only template rendering for now, but noone submitted anything else. It's however safe to assume that performance critical code will be faster (especially after some tuning).
Compatibility-wise databases are a bit of an issue, because only sqlite is working and it's slow (there is a branch to fix it though). People also reported pg8000 working with sqlalchemy for example, but I don't have a first-hand experience.
Cheers,
fijal
Are there some reasons of using Django with PyPy?
I read PyPy increases perfomance.