I'm using a C++ DLL with python which makes use of COM objects. 
I'm loading it with cdll.LoadLibray.
My application was working fine with python 2.7. Now that I'm moving to Python 3.7 my C++ DLL fails when I call: CoInitializeEx(NULL,COINIT_MULTITHREADED)
 with  error 0x80010106: Cannot change thread mode after it is set. 
By googling a bit I found some references on sys.coinit_flags = pythoncom.COINIT_MULTITHREADED but this pieces of code does not solve the issue.
It seems Python 3 is initializing COM by itself and now I cannot change the COM concurrency model.
How can I enable COINIT_MULTITHREADED?
Ok... for whoever will have this issue, after googling and trying to understand how to get Python 3 not to initialize COM or initialize it for MTA (i.e. COINIT_MULTITHREADED) I gave up and simply put CoUninitialize() in my C++ code just before calling CoInitializeEx(NULL,COINIT_MULTITHREADED) needed by my DLL.
My DLL using COM objects with COINIT_MULTITHREADED is no more working on Python 3.7