I am trying to find a new method to cluster sequence data. I implemented my method and got an accuracy rate for it. Now I should compare it with available methods to see whether it works as I expected or not. 
Is it possible to tell me what are the most famous methods in bioinformatics domain and what are the packages corresponded to those methods in Python? I am an engineer and have no idea about the most accurate methods in this field that I should compare my method to them.
It also depends on the question for which tool you need(data reduction, otu clustering, making a tree, etc..). These days you see a shift in cluster tools that uses a more dynamic approach instead of a fixed similarity cutoff.
Example:

DADA2 
UNOISE
Seekdeep

Fixed clustering:

CD-HIT 
uclust
vsearch
bioinformatics sequence clustering in Python