Coming from a Perl 5 background, what are the advantages of moving to Perl 6 or Python?
You have not said why you want to move away from Perl*. If my crystal ball is functioning today then it is because you do not fully know the language and so it frustrates you.
Stick with Perl and study the language well. If you do then one day you will be a guru and know why your question is irrelevant. Enlightment comes to those to seek it.

You called it "Perl5" but there is no such language. :P
I know Perl 5. What are the advantages of learning Perl 6, rather than moving to Python?