I am planning on using IronPython to develop a GUI interface for some python code. Do I need to know any other programming languages other than python. Also if not are there any other GUI packages/addon's to python that only use python to implement and get the final product working?
You don't need to know any other languages - modulo a few implementation differences, Python is Python is Python. You will, however, need to know the Microsoft windowing library, with which I believe you will have to interface to build a GUI.
Does IronPython just use Python or to use IronPython do I need to know other programming languages other than python?