I need to write python scripts to automate time configuration of Virtual Machines running on a ESX/ESXi host. 
I don't know which api to use...
I am able to find to python bindings for VMWare apis viz. PySphere and PyVmomi.
Could anyone please explain what is the difference between them, which one should be used?
Thanks!
Just as Josh suggested its a clean interface to VMWare API it also support a few versions of python which is nice as it will allow you to migrate from lets say python2.7 to python3.3.
What is the Difference between PySphere and PyVmomi?