Has anyone here done any benchmarking of Chameleon versus Jinja2, in respect to performance? I'm more used to the Jinja syntax, since I come from Django, but as Pyramid suggests to use Chameleon, I'm thinking if it would be nice to give it a try - despite having an awkward syntax, IMO.
Template engines are rarely the cause of performance problems, even if chameleon is slightly faster than Jinja2 I doubt the effort of learning a new template language etc. is worth it. 
Optimization of database queries and caching will probably result in more performance than you could gain by switching the template engine and take little effort.
Speed comparisons between Chameleon and Jinja2