I am testing Python 3.6 on Windows iis 10.0 and get the error 401 from browser when I call a .py file.

I have iis working on ASP pages and HTML
I have phyton.exe installed and working
I have added a .py handler in iis
I have tried to allow anonymous access and set up authorization as IUSR in iis
( And I allowed IUSR and IIS_IUSR... Full access on application directory)

I looked on Google and tried out many suggetsions!
BUT No way to esecute the script!
You have to add %s %s at the end of the Python Interpreter address.
How can I eliminate 401 error on IIS when calling Python script?