I've developed a small write-only REST api with Flask Restful that accepts PUT request from a handful of clients that can potentially have changing IP addresses. My clients are embedded Chromium clients running an AngularJS front-end; they authenticate with my API with a simple magic key -- it's sufficient for my very limited scale. 
I'm testing deploying my API now and I notice that the Angular clients are attempting to send an OPTIONS http methods to my Flask service. My API meanwhile is replying with a 404 (since I didn't write an OPTIONS handler yet, only a PUT handler). It seems that when sending cross-domain requests that are not POST or GET, Angular will send a pre-flight OPTIONS method at the server to make sure the cross-domain request is accepted before it sends the actual request. Is that right?
Anyway, how do I allow all cross-domain PUT requests to Flask Restful API? I've used cross-domaion decorators with a (non-restful) Flask instance before, but do I need to write an OPTIONS handler as well into my API?
Just an update to this comment. Flask CORS is the way to go, but the flask.ext.cors is deprecated.
use:

from flask_cors import CORS
Flask RESTful cross-domain issue with Angular: PUT, OPTIONS methods