I hope my title was clear. I'm using wxpython for making a GUI and I want it to be able to be opened, extracted, and have it work on all operating systems. I was able to include twill by finding a folder called twill inside the twill archive, which worked fine. However, I'm unable to figure out how to correctly package wxpython.
EDIT: I'm not using either. py2exe is only for windows, and bbfreeze doesn't seem to work on mac (so it's not cross platform)
Unfortunately, there's just no one stop solution so that a single installable executable will work across all operating systems.  The right solution is really to provide a different installer or executable for each OS;  For windows, use py2exe, for mac, py2app is a good choice, and for linux you should just provide a tarball with a reasonable setup.py (that you will need for the first two, anyway).
How can I package my python application with external python libraries?