I installed Python 2.6 for one user on Windows Vista.  Python works okay, but when I try: import Tkinter, it says the side-by-side configuration has errors.  I've tried tinkering with the Visual Studio runtime, with no good results.  Any ideas on how to resolve this?
It seems this is a one of the many weird Vista problems and some random reinstalling, installing/upgrading of the visual studio runtime or some such seems sometimes to help, or disabling sxs in the system configuration or writing a manifest file etc.
Though I think you should downgrade to windows XP.
How do I use Tkinter with Python on Windows Vista?