I'm trying to get a wxPython app working as an exe. I've heard that PyInstaller is now superior to py2exe. I'd like to include my .ico and two .png files that the script requires to run. What would the spec file for this look like? I can't seem to find a decent example anywhere. I have PyInstaller installed, but I can't find this "makespec" anywhere.
Checking for sys.frozen is a really good approach.  You can also look into img2py which will let you load the binary data for images into a .py file.  Later, instead of having to open files, they can be imported.
wxPython to exe with PyInstaller?