Two part question:
I have a 10x10 QTableWidget with QTableWidgetItem in each cell.
For some reason, clicking on a cell is not sufficient to edit it, I need to double-click the cell to enter it. 

Is there a way to change this behavior to single click 
Is there a way to have 2nd cell in 1st row selected and ready for editing by default when window is created?
You can also use setCurrentCell.
table.setCurrentCell(0,1)
QTableWidget.setCurrentCell (self, int row, int column)
QTableWidget how to have a cell selected for editing from code and/or with single click