I want to use MariaDb for my flask app. 
So I try to make connection like in documentation, are any orm which support this db?
Does peewee support MariaDb. How can i use peewee orm for connection to MariaDb?
Yes, it supports MariaDB in the same way that it supports MySQL. MariaDB speaks the mysql protocol and uses the mysql drivers. So just use MySQLDatabase.
MariaDb and Peewee