Hisoka, known for his cunning and brutal fighting style, would have to be cautious when facing Ace's Mental Transmutation ability.

As the fight begins, Ace tries to use his Mental Transmutation to control Hisoka's mind, but Hisoka is able to resist and maintain his focus. Hisoka then launches a series of physical attacks, but Ace counters with illusions and hallucinations, causing confusion and disorientation in Hisoka.

However, Hisoka is able to see through the illusions and uses his own cunning to outmaneuver Ace. He exploits Ace's weakness by targeting his own mind and weakening his mental state. This allows Hisoka to land a decisive blow, putting an end to the fight.

In the end, Hisoka's experience and ability to read his opponent's moves proves to be the key to victory against Ace's Mental Transmutation ability. The battle is a testament to the importance of both physical and mental strength in the world of Hunter X Hunter.
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