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1) Post-Apollo budget cuts: After the success of the Apollo program, NASA's budget was reduced, leading to the cancellation of several planned missions to the Moon and beyond.

2) Space Shuttle development: The development of the Space Shuttle program faced numerous cost overruns and delays, which resulted in the reduction of the program's scope and capabilities.

3) International Space Station: The development and operation of the International Space Station (ISS) have faced numerous budgetary constraints over the years, including delays and cost overruns.

4) Constellation program cancellation: In 2010, the Obama administration canceled the Constellation program, which aimed to return humans to the Moon and eventually send them to Mars. This decision was made in part due to budgetary constraints.

5) NASA's overall budget: NASA's budget has remained relatively flat in recent years, which has made it difficult for the agency to undertake ambitious new programs and missions.
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