Sure, here are five significant events that happened before the year 1000:

1. 476 CE: The fall of the Western Roman Empire, which marked the end of the ancient world and the beginning of the Middle Ages.
2. 527-565 CE: The reign of Justinian I, during which the Byzantine Empire reached its height of power and influence.
3. 732 CE: The Battle of Tours, in which Frankish forces under Charles Martel defeated a Muslim army, halting the spread of Islam into Western Europe.
4. 800 CE: The coronation of Charlemagne as Holy Roman Emperor, which marked the beginning of the Carolingian Empire and the revival of the Western Roman Empire.
5. 843 CE: The Treaty of Verdun, which divided the Carolingian Empire into three parts, laying the foundation for the modern nation-states of France, Germany, and Italy.
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