Sorry about that, here is a more formal explanation:

STRIPAK complexes are multi-protein signaling complexes that play important roles in regulating cell growth and division. They function as tumor suppressors by inhibiting growth-promoting signaling pathways. STRIPAK complexes contain protein phosphatases and tankyrases that degrade and dephosphorylate signaling proteins, thereby inhibiting cell proliferation and growth.

When components of STRIPAK complexes are mutated or overexpressed in cancer, their normal tumor suppressive functions are disrupted. This leads to hyperactive growth signaling and a loss of cell cycle control, enabling unregulated cell growth and proliferation - hallmarks of cancer. Therefore, STRIPAK complexes are important regulators of signaling, and their disruption contributes to cancer development and progression.
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