The mathematical and physical principles introduced during the 16th and 17th centuries, such as those of Galileo Galilei and Isaac Newton, have not been completely superseded, but rather have been refined and extended over time.

Many of the mathematical principles developed during this time, such as calculus, continue to be fundamental tools for understanding the natural world and for solving complex physical problems.

Newton's laws of motion and law of universal gravitation, which were introduced in the late 17th century, remain cornerstones of classical mechanics and continue to be widely used to this day. However, these laws have been refined and extended, particularly in the 20th century with the development of Einstein's theory of general relativity and quantum mechanics.

Our understanding of physical phenomena has continued to expand and improve over time, and today we have a much more complete and accurate understanding of many physical processes, including the nature of light, the behavior of subatomic particles, and the behavior of the universe on the largest scales.

So while the mathematical and physical principles introduced during the 16th and 17th centuries have been refined and extended, they still form the basis of our modern understanding of the natural world.
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