Considering the 21st century, the following songs have won multiple Grammy awards:

1. "Clarity" by Zedd feat. Foxes - won the Grammy for Best Dance Recording in 2014 and Best Remixed Recording, Non-Classical in 2015.

2. "Don't Let Me Down" by The Chainsmokers feat. Daya - won the Grammy for Best Dance Recording in 2017 and Best Remixed Recording, Non-Classical in 2018.

3. "Where Are Ü Now" by Skrillex and Diplo with Justin Bieber - won the Grammy for Best Dance Recording in 2016 and Best Remixed Recording, Non-Classical in 2016.

4. "Strobe" by Deadmau5 - won the Grammy for Best Remixed Recording, Non-Classical in 2009 and Best Dance/Electronic Album in 2021.

If we were to consider only one EDM song, "Strobe" by Deadmau5 is the only one to have won multiple Grammy awards in the 21st century. The song is an instrumental piece and does not have lyrics. It is known for its hypnotic melody and has been described as a masterpiece of the progressive house genre. The song's title refers to the use of strobe lights in clubs and other dance venues.
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