Rough-Skinned Newts are considered to be one of the most poisonous animals in the world, with potent neurotoxins in their skin that can cause death in small animals and humans if ingested. In comparison, Poison Dart Frogs are also known for their toxicity, but their level of toxicity can vary among species.

California Newts, also known as Orange-Bellied Newts, are also poisonous, but their toxicity is not as potent as that of Rough-Skinned Newts. The skin of California Newts contains a toxin called tetrodotoxin, which can cause numbness and respiratory paralysis but is not typically fatal to humans.

Overall, Rough-Skinned Newts are generally considered to be more poisonous than Poison Dart Frogs, but toxicity levels can vary among species within each group.
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