The present invention relates to a brain plasticity control device to increase or suppress brain plasticity by applying theta-burst ultrasound stimulation, and a brain plasticity control method thereof. According to the present invention, the neural plasticity control device using theta-burst ultrasound and the method thereof can safely control the plasticity of the brain in a non-invasive way without surgical operation. In addition, unlike conventional transcranial magnetic stimulation or transcranial electrical stimulation, transcranial ultrasound stimulation has a high spatial resolution to control stimulation control in a required brain region and has the permeability, spatial resolution, and duration of the follow-up effect are significantly increased more than those of the conventional transcranial magnetic stimulation using theta-burst pulses so that the effect lasts up to 1 hour even after a few minutes of stimulation. Accordingly, the neural plasticity control device using theta-burst ultrasound and the method thereof increases or suppresses the plasticity of the brain according to an application pattern of theta-burst pulse, thereby being useful in brain function-related fields such as improvement of learning ability, memory, and the like through long-term strengthening and suppression of the brain, prevention and treatment of various neurological diseases such as depression and the like, and regulation of abnormally increased brain activity such as epilepsy and seizures. According to the present invention, a theta-burst ultrasound stimulation generation unit comprises a pulse generator, a function generator, and a transducer.
- Neural Plasticity Control Device and Method Using Theta-Burst Ultrasound