PROBLEM TO BE SOLVED: To provide use of PDE7 inhibitors for treating movement disorders.SOLUTION: The invention provides a method for a treating motility abnormality associated with the pathology of a neurological movement disorder such as Parkinson's disease or Restless Leg Syndrome by administering a therapeutically effective amount of a PDE7 inhibitor. One aspect of the invention provides administration of a PDE7 inhibitor in combination with a dopamine agonist or precursor thereof such as levodopa. In another aspect of the invention, the PDE7 inhibitor may be more selective to PDE7 than to other molecular targets (i) that are known to be participating with pathological conditions of Parkinson's disease or (ii) that are targeted by other drugs being therapeutically effective to treat Parkinson's disease.SELECTED DRAWING: None
USE OF PDE7 INHIBITORS FOR TREATING MOVEMENT DISORDERS