Substituted 1-(alkoxyphenyl)piperazines are disclosed as partial dopamine agonists useful in the treatment of dopaminergic dysregulation. The compounds 1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-3-phenyl-2-imidazolidinone and 1-(3-chlorophenyl)-3-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-2-imidazolidinone, are preferred in the treatment of Parkinsonism, schizophrenia, and drug addiction.
Substituted 1-(alkoxyphenyl)piperazines with cns and antihypertensive activity