The compounds of formula (I) may be used in medicaments for use as serotonin-reuptake inhibitors in the treatment of depression, obsessive-compulsive disorders, phobias, impulsive disorders associated with drug abuse, bulimia nervosa and anxiety. In formula (I): R1 and R2 are independently H or a linear or branched (C1-C6)alkyl group; A represents a linear or branched (C1-C6) alkylene group, a linear or branched (C2-C6)-alkenylene group or a linear or branched (C2-C6)alkynylene group; and G1 represents a grouping -N(R3)(R4), wherein R3 and R4 are independently H, a linear or branched (C1-C6)alkyl group, a (C3-C8)cycloalkyl group, a (C3-C8)cycloalkyl-(C1-C6)alkyl group in which the alkyl moiety is linear or branched, an optionally substituted aryl group, an optionally substituted aryl-(C1-C6)alkyl group in which the alkyl moiety is linear or branched, an optionally substituted heteroaryl group, or an optionally substituted heteroaryl-(C1-6) alkyl group in which the alkyl moiety is linear or branched; or G1 represents a heterocycloalkyl group, bonded to A by any one of the ring junctions and optionally substituted at any one of the ring positions by a linear or branched (C1-C6)alkyl group, a (C3-C8)cycloalkyl group, a (C3-C8)cycloalkyl-(C1-6)alkyl group in which the alkyl moiety is linear or branched, a nitrile group, a carboxy group, a linear or branched (C1-C6)alkoxy-carbonyl group, a carbamoyl group (optionally substituted by one or two substituents: linear or branched (C1-C6)alkyl, (C3-C8)cycloalkyl, optionally substituted phenyl and/or optionally substituted benzyl), an optionally substituted aryl group, an optionally substituted aryl(C1-C6)alkyl group in which the alkyl moiety is linear or branched, an optionally substituted heteroaryl group, or an optionally substituted heteroaryl-(C1-C6)alkyl group in which the alkyl moiety is linear or branched.
Cyano-indole serotonin-reuptake inhibitor compounds