The present invention is a method of diagnosing the presence of a persistent occlusion in a myocardial infarct patient undergoing thrombolytic therapy. The method comprises detecting a series of three variables from the patient and then generating the probability of the presence of a persistent occlusion from those variables. The first variable comprises a serum create kinase MB (CK-MB) level from a patient at the onset of thrombolytic therapy (10). The second variable comprises a second CK-MB level in the patient at a predetermined time after the onset of thrombolytic therapy (20). The third variable comprises the presence or absence of chest pain a predetermined time after the onset of thrombolytic therapy (30). In a preferred embodiment of the present invention, the second and third variables are detected within thirty minutes of each other and within about one to about three hours after the initial variable is detected. In an alternate embodiment, a fourth variable reflecting the time from onset of chest pain (40) to the beginning of thrombolytic therapy is included in the regression model.
METHOD OF ASSESSING REPERFUSION AFTER THROMBOLYTIC THERAPY