NON-NEURONAL SNARE-CLEAVING BOTULINUM NEUROTOXINS 5 The present invention provides a modified botulinum neurotoxin A (BoNT/A) L-chain protease that demonstrates enhanced cleaveage of human SNAP-23 (hSNAP-23) relative to unmodified (wild-type) BoNT/A L-chain protease, together with the use thereof for cleaving hSNAP-23. 18139585 1 (GHMatters) P46034AU01
Non-neuronal snare-cleaving botulinum neurotoxins