Provided is a CD24 protein for repressing host response to the danger-associated molecular patterns (DAMP) in a subject, wherein an amino sequence of the CD24 protein consists of a mature human CD24 polypeptide fused to a Fc portion of a human immunoglobulin (Ig) protein, wherein a sequence of the mature human CD24 polypeptide consists of the sequence of SEQ ID NO: 1, and wherein the CD24 protein is free of alanine or valine in a position directly C-terminal relative to SEQ ID NO: 1.
CD24 PROTEIN TO SUPPRESS HOST RESPONSE TO DAMP