FIELD: chemistry.SUBSTANCE: invention relates to the novel compound of formula (1) and its enantiomer. Above compound has affinity binding properties for subunits αδ of potentially dependent calcium channels and can be used in treatment of neuropathic pain, in particular headache and migraine, in treatment of diseases of the central nervous system and/or peripheral nervous system, for example, selected from epilepsy, ischemic cerebrovascular disease, stroke, cerebral neoplasms, Alzheimer's disease, Peak's disease, Huntington's disease, dementia, Parkinson's disease and others. In formula (1)Formula 1 Rrepresents Calkyl group, Risor, and Ris hydrogen or Calkyl group. Also, the invention relates to methods for producing the compound of formula 1 by reducing the compound of formula 12.Formula 12Formula 2a. Above enantiomer of formula 2a can be obtained by separating a mixture of the enantiomers of formula 1. In the indicated compounds of the group, R, R, Rhave the above meaning. In addition, the invention relates to new intermediate compoundsFormula 16 andFormula 14, where Rhas the above values, Rrepresents -R, -CN, -CONH, -COOH, -(C=NH)NHOH.EFFECT: proposed analogues of gamma-aminobutyric acid (gaba) for treatment of pain and other disorders.19 cl, 1 tbl, 5 ex
GAMMA-AMINOBUTYRIC ACID (GABA) ANALOGUES FOR TREATMENT OF PAIN AND OTHER DISORDERS