Methods and combinations relate to information obtained by using a brain imaging technique. In one example, there is a method of determining information reflecting impact of a product on skin sensitivity. Such a method includes causing at least one stimulus to be applied to skin of a subject, the stimulus being capable of provoking a brain reaction reflecting the presence of sensitive skin; receiving first information obtained using a brain imaging technique, the first information relating to the reaction of at least one brain region to the stimulus; causing a product to be applied or administered to the subject, the product being a product intended to impact skin sensitivity; receiving second information obtained using a brain imaging technique, the second information relating to behavior of the brain region after application or administration of the product to the subject; and determining third information as a function of the first and second information, the third information relating to the impact of the product on skin sensitivity.
Methods and combinations relating to information obtained using brain imaging techniques