A system and method control prostheses (200), other devices with signals received by sensors, implanted directly in the brain or other parts of the nervous system of a subject, and transmitted to an external receiver. Included in the system are sensors (5) in the form of bundles of small, insulated, flexible wires (10), configured in a parallel or twisted array, which are used to receive multicellular signals from small clusters of neurons. A new 'calibration/adaptation' system is developed, in which the neural signals are cross-correlated with the parameters of a set of standardized or model movements as the subject/patient attempts to emulate the model movements, and on the basis of the correlations the neural signals that are best suited for control of the corresponding movement or movement parameter of the external devices are selected.
SYSTEM AND METHODS FOR CONTROLLING DEVICES BY BRAIN SIGNALS