In order to reduce computation time and provide more accurate solutions for bi-directional, multi-modal image registration, a learning-based unsupervised multi-modal deformable image registration method that does not require any aligned image pairs or anatomical landmarks is provided. A bi-directional registration function is learned based on disentangled shape representation by optimizing a similarity criterion defined on both latent space and image space.
Unsupervised deformable registration for multi-modal images