The multi-epitope SARS-COV2 Spike peptides are analyzed for their ability to form association or binding complex with HLA-DR1 and human TLR8 by using computer modeling and molecular docking experiments. These peptides are identified as candidates for vaccine development as well as antibody-based immunotherapy.
Identification of SARS-COV2 Spike glycoprotein epitope amino acid sequences recognized by Human class II antigen presenting determinant HLA-DR1 and innate immune responder Toll-like receptor 8 by using computer modeling and molecular docking methods.