The disclosure relates to methods of diagnosing psychiatric disorders (e.g., schizophrenia, bipolar disorder), methods of classifying a sample as derived from an individual having a psychiatric disorder, methods of identifying compounds for use in modulating psychiatric disorders, methods of modulating psychiatric disorders and methods of assessing efficacy of treatment of psychiatric disorders. The disclosure also relates to oligonucleotide microarrays containing probes for genes which are differentially expressed between schizophrenic individuals and normal individuals and to oligonucleotide microarrays containing probes for genes which are differentially expressed between bipolar individuals and normal individuals. The disclosure also relates to methods of classifying a sample as a pre-frontal cortex and/or cerebellum sample, as well as to oligonucleotide microarrays containing probes for genes which are differentially expressed in pre-frontal cortex and cerebellum.
Gene expression associated with psychiatric disorders