The present invention provides a method for the treatment of depressive disorders in a patient comprising the step of pre-treating the subject with an antidepressant therapy comprising administration the patient modafinil and pharmacologically active selective serotonin reuptake inhibitors. According to the invention the method provides decreasing the onset time of an antidepressant in a subject and effective treatment of residual symptoms in such patients.
COMBINATION OF THE ANALEPTIC MODAFINIL AND AN ANTIDEPRESSANT FOR THE TREATMENT OF DEPRESSION