PROBLEM TO BE SOLVED: To provide computers employing biomolecules that can be compatible with biological environments, rendering them amenable for use in complex-disease diagnostics or even treatments.SOLUTION: Provided are nucleic acid translators capable of carrying out logic operations with improved efficiency, maximized output and reduced off-target effects, in particular in a biological system. Methods of using these translators to transduce signals are also provided.SELECTED DRAWING: None
ROTATIONALLY SEQUESTERED TRANSLATORS