PURPOSE: To use bretazenil, which is useful as an anticonvulsant, an anxiety- relieving agent, etc., as a somnifacient capable of inducing sleeping near to natural sleep at a low dose. CONSTITUTION: Bretazenil of the formula, i.e., t-butyl(S)-8-bromo-11,12,13,13a- tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1- carboxylate is used for treating sleep disorder. That is, a medicine which can induce sleep near to natural sleep is produced from an effective dose of bretazenil and a therapeutically inert support. Bretazenil can shorten the inducing time for sleep and keep it in a long stable state.
TREATING AGENT FOR DISTURBANCE OF SLEEPING