To provide light-activated two-component protein binding matrix.SOLUTION: A binding pair comprises: a first binding member being a spiropyran molecule, which is in a first isomer configuration under a first condition and in a second isomer configuration under a second condition; and a second binding member being an isomer-specific peptide aptamer. The first binding member and the second binding member reversibly associate with or disassociate from each other when the spiropyran molecule changes the isomer configurations. The second binding member has a binding affinity for the first isomer configuration of the spiropyran, and a lower binding affinity for the second isomer configuration of the spiropyran. The second binding member associates with one of the isomer configurations and does not associate with the other of the isomer configurations. The spiropyran molecule in the first isomer configuration is represented by a prescribed structural formula, and the spiropyran molecule in the second isomer configuration is represented by a prescribed structural formula.SELECTED DRAWING: None
LIGHT-ACTIVATED TWO-COMPONENT PROTEIN BINDING MATRIX