A method is disclosed for detecting polypharmacy in a subject that involves assaying a urine sample from the subject for a plurality of drugs or drug metabolites. The disclosed methods can further involve detecting potential adverse drug reactions in the polypharmacy of the subject. In addition, the method can further involve selecting a drug for treating the subject that does not interact with any drugs in the polypharmacy of the subject.
METHODS AND SYSTEMS FOR DETECTING POLYPHARMACY