The method involves bringing an object into the magnetic field. Transverse magnetization is generated and refocused to produce an echo signal with echo time TE. TE is incremented in steps, to obtain 2D-data values in F1 bandwidth as the bandwidth of proton-proton J-coupling. The data values are processed to obtain chemical shift frequencies and J-coupling frequencies along F2 and F1 axes.
Quantitative in vivo spectroscopy method for brain using magnetic resonance 2-D spectroscopy