A neural network electrical activity detection system and a screening method for neuropsychiatric drugs based on the system. The detection system mainly consists of a neural network system constructed in vitro, a photoelectric signal conversion system, and a monitoring and analysis system. On this basis, the detection system can also be used for theoretical research of a nervous system and early screening and testing of potential neuropsychiatric drugs. In the detection system, a neural network is constructed in vitro, which facilitates large-scale preparation; a pathological neural network model can be established, stimulation intervention is not required, the natural physiological working state of the neural network can be kept, network electrical activities can be regulated and controlled in a certain range, drug targets can be introduced by means of viruses, electric signals are converted into optical signals, a collection system is simplified, costs are reduced, high-throughput screening is easy to implement, high-throughput data analysis is performed by means of targeted software, labor costs are reduced, and the present invention has a very good prospect.
NEURAL NETWORK ELECTRICAL ACTIVITY DETECTION SYSTEM AND SCREENING METHOD FOR NEUROPSYCHIATRIC DRUGS BASED ON SYSTEM