In accordance with the invention, a compound with a protective action for nerve cell can be reselected by adding PPARdelta agonist to a culture cell system where toxic substances such as thapsigargin, MPP<SUP>+</SUP> and staurosporine are preliminarily allowed to react and reselecting a compound improving the survival rate. The compound selected by such method can be used as an active ingredient of a therapeutic agent for neurodegenerative diseases such as cerebral infarction and Parkinson's disease. Thus, the invention is very useful for research works for creating novel pharmaceutical agent.
Remedy for cerebral neurodegenerative diseases using ppar agonist