Provided are a marker gene for identifying and classifying dopaminergic precursor cells (DPC), a screening method therefor and use thereof. The marker gene is a combination of 12 genes having specific up-regulation expression in the DPC cells relative to the neural stem cells (NSCs). The screening of the marker gene is based on a high-throughput RNA sequencing technology. In the samples of the NSC cells and the DPC cells, genes of which the specific expression is significantly up-regulated in the DPC cells are detected, and by bioinformatic analysis, a group of candidate genes capable of regulating the differentiation process of neural stem cells to dopaminergic neurons are identified. The marker gene combinations provided can be used to identify and classify DPC cell products for clinical treatment and to control the quality of the DPC cell products for clinical application.
MARKER GENE FOR IDENTIFYING AND CLASSIFYING DPC CELL, SCREENING METHOD THEREFOR AND USE THEREOF