The invention provides application of N-linoleoyl tyrosine in preparation of a medicine with a neuroprotective effect. Action mechanism research finds that N-linoleoyl tyrosine (NITyr) can relieve H2O2-induced cell injury and oxidative stress in PC12 cells through autophagy, and in addition, NITyr effectively maintains ROS steady state in the cells through a CB1 receptor, reduces cell injury and enhances cell autophagy. The discovery shows that the compound can be applied to occurrence and development of cardiovascular diseases, Alzheimer's disease and other chronic degenerative diseases caused by oxidative stress rise and excessive accumulation of reactive oxygen species (ROS), and has comprehensive development and application prospects.
Application of N-linoleoyl tyrosine in preparation of medicine with neuroprotective effect