PROBLEM TO BE SOLVED: To provide, especially, mammals except human-beings in which a gene of GIT1 (G protein-coupled receptor kinase interacting protein 1) which is neural synapse protein of the brain is knocked out, as an attention deficiency hyper activity disorder model, and to provide a new screening method of medicine for administering medicine which is an ADHD candidate substance to induce recovery by using a GIT1 knockout mouse.SOLUTION: Regarding molecular-biological, cytobiological, electrobiological, and zoological analysis to a GIT1 knockout mouse, hyperactivity which is attention deficiency hyperactivity disorder and recover of theta waves in the frontal lobe are observed by administration of medicine which is a candidate substance, and screening of a new medicine for inducing recovery of the attention deficiency hyperactivity disorder is performed.
GIT1 KNOCKOUT MOUSE AND MEDICINE SCREENING METHOD USING THE SAME