FIELD: pharmacology.SUBSTANCE: invention relates to derivatives of 1,4-benzothiazepine (I),as well as to pharmaceutical compositions and application.EFFECT: new compounds are obtained that can be used to treat or prevent RyRs-associated diseases and states, namely cardiac disorders, musculoskeletal disturbances and central nervous system disturbances.27 cl, 11 dwg, 3 tbl
MEANS FOR TREATMENT OF VIOLATIONS INVOLVING RIANODIN RECEPTORS MODULATION