PROBLEM TO BE SOLVED: To provide cells exhibiting neuronal progenitor cell characteristics, and a method for making them from a marrow adherent stem cells by regulating cellular pathways in the marrow adherent stem cells that are associated with glial transdifferentiation of the marrow adherent stem cells.SOLUTION: The method for producing cells in vitro for treating central or peripheral nervous system diseases is obtained by the following step of: incubating marrow adherent stem cells (MASCs) with inhibitors of JAK/STAT signal transduction, wherein the MASCs are not transfected by polynucleotides that encode notch intracellular domain.
CELL EXHIBITING NEURONAL PROGENITOR CELL CHARACTERISTIC