Methods of predicting the level of symptom severity in individuals with autism spectrum disorders (ASD) that may include autism disorder, Asperger syndrome, and pervasive developmental disorder not otherwise specified. Therapeutic methods of delivering DUF1220 domain CON1 subtype domain protein products or fragments or mimetics thereof or antagonists thereof to treat ASD or ameliorate symptoms of ASD in an individual.
Diagnosis and prognosis of severity of autism spectrum disorders