PROBLEM TO BE SOLVED: To provide methods of treating a patient suffering from non-24-hour disorders.SOLUTION: The invention relates to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light perception impaired patients, e.g., blind patients, and to methods of measuring the circadian rhythm. The invention also relates to methods for the melatonin agonist to agonize MT1R and MT2R.SELECTED DRAWING: Figure 6
TREATMENT OF CIRCADIAN RHYTHM DISORDERS