It is found that, in an Alzheimer's disease patient, an asparagine at position 279 of a tau protein is deamidated and modified by an aspartic acid. The Alzheimer's disease can be identified and diagnosed by using a reagent for specifically recognizing a peptide in which the asparagine at position 279 of the tau protein is modified by the aspartic acid.
SPECIFIC BINDING REAGENT FOR DETECTING QUALITATIVE DIFFERENCE OF 4-REPEAT TAU, AND DETECTION METHOD, DETECTION KIT, AND MEDICATION SCREENING METHOD USING SAME