Methods and devices providing for bilateral stimulation of left and right splanchnic nerves. Some embodiments of the method increase satiety, reduce appetite, affect gastric motility, and/or reduce food intake, resulting in weight loss. Some methods provided take advantage of anatomy, physiology, and natural body time periods to change stimulation locations and patterns to prevent the body from ignoring the administered stimulation signals in order to continue to induce weight loss over long time periods.
EFFERENT AND AFFERENT SPLANCHNIC NERVE STIMULATION