Method for identification of treatments and preventative agents for brain aging, subjective cognitive impairment, mild cognitive impairment, Alzheimer's disease and other degenerative dementias. Method includes (a) identification of diagnosis and stage of subject, (b) identification of the duration of stage, condition and/or disorder, (c) identification of prognostic markers based upon a formula incorporating the duration of condition and/or stage, (d) prospective separation of prognostic subgroups based upon outcome which is defined in these conditions as progression to subsequent stage(s), (e) employment of a putative prognostic marker for an appropriate time period, based upon the formula incorporating the duration of condition and/or stage, (f) application of in vivo, methodology specific techniques, in conjunction with stage specific prognostic subgroups, for the appropriate time period, for identification, prospectively, of useful markers, and (g) employment of these markers to identify useful therapeutic agents for prevention and treatment.
STAGE SPECIFIC PROGNOSTIC IN VIVO MARKERS OF BRAIN AGING AND DEMENTIA