The present invention relates to the development of an active nanowire-based waveguide probe, and the quantitative probing of Cu2+ ions naturally present in living single neurons on the basis thereof. Specifically, the present invention allows intracellular Cu2+ ions to be quantitatively measured through the direct observation of photoluminescence (PL) quenching by the Cu2+ ions within the nanowire by inserting a nanowire waveguide probe into living single cells.
METHOD FOR QUANTITATIVELY PROBING METAL ION WITHIN LIVING SINGLE CELL, AND NANOWIRE-BASED WAVEGUIDE PROBE FOR USE THEREIN