The present invention provides a process of producing an immortalized hybrid neuronal cell comprising the steps of transducing a primary embryonic brain cell from a specific brain region with a temperature-sensitive oncogene to produce a transductant cell, and fusing the transductant cell with a mature primary neuron from the same brain region to produce the hybrid cell. Hybrid cells produced by such a process are also provided.
HYBRID NEURONAL CELL LINES COMPOSITIONS AND METHODS