The present invention relates to a method for diagnosing brain tumor through a bacterial metagenome analysis. More specifically, the present invention relates to a method for diagnosing brain tumor by analyzing an increase or a decrease in the content of specific bacteria-derived extracellular vesicles by performing a bacterial metagenome analysis using samples of normal individuals and tested subjects. Extracellular vesicles secreted by bacteria present in the environment are absorbed into a body and may directly affect the occurrence of inflammation. Also, it is difficult to diagnose brain tumor early before symptoms appear, and thus it is difficult to perform effective treatment. Accordingly, according to the present invention, by diagnosing the risk of brain tumor in advance through the metagenome analysis of bacteria-derived extracellular vesicles using human body-derived samples, it is possible to diagnose and predict the risk group of autism early. In addition, proper management can delay or prevent the onset of disease. Moreover, an early stage diagnosis is possible even after the onset of the diseases, and thus the occurrence rate of brain tumor is reduced. Also, a therapeutic effect can be improved. Furthermore, by avoiding exposure to causative factors through a metagenome analysis in a patient diagnosed with brain tumor, the course of diseases can be improved, or recurrence can be prevented.
Method for diagnosis of brain tumor using analysis of bacteria metagenome