A method and apparatus for automatic spinal canal segmentation in medical image data, such as computed tomography (CT) image data, is disclosed. An initial set of spinal canal voxels is detected in the 3D medical image using a trained classifier. A spinal canal topology defined by a current set of spinal canal voxels is refined based on an estimated medial line of the spinal canal. Seed points are sampled based on the refined spinal canal topology. An updated set of spinal canal voxels is detected in the 3D medical image using random walks segmentation based on the sampled seed points. The spinal canal topology refinement, seed points sampling, and random walks segmentation are repeated in order to provide cascaded random walks segmentation to generate a final spinal canal segmentation result.
Automatic spinal canal segmentation using cascaded random walks