Behavioral sensitization to psychostimulants involves neuroadaptation of stress-responsive systems. The present invention provides glucocorticoid-induced receptor nucleotides and proteins belonging to G protein-coupled receptor superfamily. The present invention also provides methods methods for determining susceptibility of psychogenic disorders such as depression, anxiety and addiction as well as the development of treatments for central nervous system disorders through glucocorticoid-induced receptor expression modulation.
GLUCOCORTICOID-INDUCED RECEPTOR AND METHODS OF USE