A device to measure the state of biological metabolism comprises: a light source to generate ultrashort light pulses of two or more wavelengths; a light dividing means to divide the ultrashort light pulse generated by the light source into a reference light pulse and a sample light pulse; a reference light pass to guide the reference light pulse divided by the light dividing means; a sample light pass to guide the divided sample light pulse to a living body; a delay means to delay the reference light pulse; a converging means to converge the reference light pulse; a nonlinear optical crystal to generate second harmonic; a muliplier phototube to obtain the ave. of the counted values.
TISSUE METABOLISM MEASURING APPARATUS