A real-time quantitative fluorescent probe for detecting A1555G mutation in maternal inherited mitochondrial deafness gene and its usage are disclosed. Taqman mutant and wild-type probes and a pair of primers are designed. Genetype of A1555G mutation in maternal inherited mitochondrial deafness gene is analyzed through real-time quantitative Taqman probe method. Therefore maternal inherited mitochondrial deafness can be diagnosed.
PROBE FOR DETECTING MATERNAL INHERITED MITOCHONDRIAL GENETIC DEAFNESS A1555G MUTATION AND ITS USAGE