The present invention relates to novel benzazepine derivatives of formula (I); wherein: R<SUP>1 </SUP>represents -C<SUB>3-7 </SUB>cycloalkyl optionally substituted by C<SUB>1-3 </SUB>alkyl; R<SUP>2 </SUP>represents -aryl, -heterocyclyl, heteroaryl, -aryl-X-C<SUB>3-8 </SUB>cycloalkyl, cycloalkyl, -aryl-X-aryl, -aryl-X-heteroaryl, -aryl-X-heterocyclyl, -heteroaryl-X-C<SUB>3-8 </SUB>cycloalkyl, -heteroaryl-X-aryl, -heteroaryl-X-heteroaryl, -heteroaryl-X-heterocyclyl, -heterocyclyl-X-C<SUB>3-8 </SUB>cyclooalkyl, -heterocyclyl-X-aryl, -heterocyclyl-X-heteroaryl or -heterocyclyl-X-heterocyclyl; X represents a bond, O, CO, -CH<SUB>2</SUB>O-, -COCH<SUB>2</SUB>-, -COCH<SUB>2</SUB>O-, -CONR<SUP>2b</SUP>-, -COCH<SUB>2</SUB>NR<SUP>2b</SUP>CO-, -CSNH-, SO<SUB>2</SUB>, -SO<SUB>2</SUB>C<SUB>1-3 </SUB>alkyl-, -SO<SUB>2</SUB>C<SUB>2-3 </SUB>alkenyl-, -COC<SUB>2-3 </SUB>alkenyl-, -CO-C(R<SUP>2a</SUP>)(R<SUP>2b</SUP>)- or -CO-C(R<SUP>2a</SUP>)(R<SUP>2b</SUP>)CH<SUB>2</SUB>-; having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.
Benzazepine derivatives for the treatment of neurological and psychiatric disorders