Provided herein is a variant allele of a gene encoding a serotonin 1B receptor, A-161T, along with cloning vectors for replicating such variant alleles, and expressing vectors for expressing the variant alleles to identify alterations in the expression of serotonin 1B receptors, for identifying individuals predisposed to addictive, neurologic or psychiatric diseases.
Polymorphism of the human serotonin 1B receptor gene, diagnostic methods and methods of treatment based thereon