Compounds are disclosed according to structural diagram (I), wherein R<1>, A, D and E are as defined in the specification. Also disclosed are methods for the treatment of pain and pharmaceutical compositions comprising a pain-ameliorating effective amount of a compound in accord with structural diagram (I).
1,2,5,10-TETRAHYDROPYRIDAZINO 4,5-B QUINOLINE-1,10-DIONES AND THEIR USE FOR THE TREATMENT OF PAIN