Human CNS receptor-encoding DNA is provided from which more than one form of the receptor protein, an edited form and an unedited form, is expressed <u>in vivo</u>. The edited and unedited receptor forms are functionally distinct, and appear to be selectively expressed. Thus, a CNS receptor-encoding gene that is subject to such editing has value in screening compounds for potential therapeutic utility.
GLUTAMATE RECEPTOR (OR EAA RECEPTOR) POLYNUCLEOTIDES AND THEIR USES