The invention relates to novel oxabicycloheptane derivatives of the formula: <IMG> where D is a hydrogen or halogen atom, or a hydroxyl, alkoxy, arylalkoxy, acyloxy, dialkylcarbamoyloxy or amidoalkyloxy group; B is a substituted or unsubstituted phenyl, thienyl or furyl group; /A\\ is the group <IMG> (where ? is 0 or 1; m and n are each 1 or more, provided that m + n is an integer of 2 - 8; R1 is an alkylamino, dialkylamino, arylalkylamino, morpholino, thiomorpholino, 1-pyrrolidinyl, piperidino, N-alkyl-piperazinyl, N-hydroxyalkylpiperazinyl or pyrrolizidinyl group; and R2 is a lower alkyl or hydroxyl group), or the group <IMG> (where ?, m, n, R1 and R2 have the aforesaid meanings), or the group <IMG> (where R3 and R4 which may be the same or different each represents a hydrogen atom or a lower alkyl, alkoxy-carbonyl or acyl group), or the group <IMG> (where m, ?, n, R1 and R2 have the aforesaid meanings). The oxabicycloheptane derivatives of the invention are effective in ameliorating or eliminating the symptoms that appear either as a result of organic disorders in the brain or on account of pathergasia. These compounds also have antidepressant effects and are useful as psychopharmaceuticals.
OXABICYCLOHEPTANE DERIVATIVES