The invention provides methods of identifying biomarkers associated with autism or autism spectrum disorder based upon quantitative trait association analyses using genome-wide genotype data combined with ease-control association analyses using distinct ASD phenotypes identified on the basis of symptomatic profiles, including deficits in language usage, non-verbal communication, social development, play skills, and insistence on sameness and rituals. Also provided are compositions identified using the methods of the invention and use thereof.
SINGLE NUCLEOTIDE POLYMORPHISM BIOMARKERS FOR DIAGNOSING AUTISM