Systems and methods for serial analysis of electrocardiograms are presented, wherein serial electrocardiographic (ECG) assessment is incorporated with three-dimensional vectorial analysis of the cardiac electrical signal, using changes in novel 3D-based vectorial markers over time to improve diagnostic sensitivity for acute coronary syndromes (ACS), and improve differentiation of ACS from the broad range of heart diseases that resemble ACS on ECG.
System and methods for serial analysis of electrocardiograms