The present invention provides a method of increasing neural stem cell numbe rs or neurogenesis by using prolactin. The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neuron s or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural st em cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from neurodegenerative diseases or conditions. In addition, since neural stem cel ls are a source for olfactory neurons, the present invention also provides methods of increasing olfactory neurons and enhancing olfactory functions.</ SDOAB>
PROLACTIN INDUCED INCREASE IN NEURAL STEM CELL NUMBERS AND THERAPEUTICAL USE THEREOF