The present invention relates to a sensor for the detection of Neurotrophic Factor (NF). The sensor, preferably a Screen Printed Electrochemical sensor (SPE), has a working electrode coated by a Molecularly Imprinted Polymer (MIP) imprinted by a NF. The invention also relates to a method for preparing such a sensor and comprising the steps of 1) formation of a cleavable linking layer on the working electrode of the sensor; 2) immobilization of NF molecules on the cleavable linking layer; 3) polymerization of m-PD on the working electrode of the sensor; and 4) cleavage of the cleavable linking layer, thereby removing the NF molecules from the MIP layer.
Molecularly imprinted polymer based electrically conductive surface, method of its preparation and sensor for neurotrophic factors