An ultrasound deep brain stimulation (DBS) method and system, the ultrasound DBS method comprising: conducting medical imaging on the head of animal or human being, and generating image data; according to the image data, establishing a three-dimensional digital model of the head; according to a structure, a density, and acoustic parameter information of an ultrasound transducer array (607), establishing a three-dimensional digital model of the ultrasound transducer array (607); according to the three-dimensional digital model of the head, the three-dimensional digital model of the ultrasound transducer array (607), the structure, density, and acoustic parameters of skull and brain tissue, and the structure, density, and acoustic parameter of the ultrasound transducer array (607), generating a first ultrasound transmission sequence; controlling the ultrasound transducer array (607) to transmit an ultrasonic wave according to the first ultrasound transmission sequence, and implementing the ultrasound DBS with respect to a brain nerve nucleus to be stimulated. In the method and system, ultrasound noninvasively penetrates the skull and is focused on a deep brain region. Different ultrasound transmission sequences can realize ultrasound neural regulation and research into the mechanism of action thereof can be performed.
ULTRASOUND DEEP BRAIN STIMULATION METHOD AND SYSTEM