The invention relates to spatial distribution of pathological image patterns in 3D image data. A method and for quantifying a three-dimensional medical image volume are provided. An embodiment of themethod includes: providing a two-dimensional representation image (RI) based on the medical image volume (IV); defining a region of interest (ROI) in the two-dimensional representation image (RI); generating a feature signature (fROI) for the region of interest (ROI); defining a plurality of two-dimensional image patches (P) in the medical image volume (IV); calculating, for each of the image patches, a degree of similarity (S) between the region of interest (ROI) and the respective image patch (P) on the basis of the feature signature (fROI); visualizing the degrees of similarities (S).
SPATIAL DISTRIBUTION OF PATHOLOGICAL IMAGE PATTERNS IN 3D IMAGE DATA