The present invention relates to a schizophrenia-like cognitive dysfunction animal model; a method of preparing the same; and a method of evaluating schizophrenia-like cognitive dysfunction by using said model. Specifically, the present invention relates to the preparation of a mammal showing continuous cognitive abnormality after sexual maturation, by allowing an excessive presence of interleukin 1 or an analog thereof and/or an intracellular signal transducer induced by interleukin 1 or an analog thereof in the body of young animal during the stages of brain function development; and a method of evaluating cognitive dysfunction by ethologically measuring the cognitive abnormality in the animal.
SCHIZOPHRENIA-LIKE MENTAL DISEASE MODEL ANIMAL, METHOD OF CONSTRUCTING THE SAME AND USE THEREOF