PCT No. PCT/DK85/00071 Sec. 371 Date Mar. 31, 1986 Sec. 102(e) Date Mar. 31, 1986 PCT Filed Jul. 25, 1985 PCT Pub. No. WO86/00902 PCT Pub. Date Feb. 13, 1986.The present invention relates to hitherto unknown compounds of the formula I <IMAGE> (I) in which R1 is a straight or branched, saturated or unsaturated aliphatic or alicyclic C1-C10 hydrocarbon radical, an aryl or an aryl-C1-C4-alkyl radical, R1 if desired being unsubstituted or substituted with straight or branched C1-C4-alkyl, amino, C1-C4-alkamino, di-(C1-C4-alkyl)-amino, carboxy, C1-C4-alkoxycarbonyl, hydroxy, C1-C4-alkoxy, phenoxy, mercapto, C1-C4-alkylthio, phenylthio, halogen, trifluoromethyl; R2 stands for hydrogen, C1-C8-alkyl, aryl-C1-C4-alkyl or halogen; X is O or S, and n is an integer from 0 to 2; with the proviso that R2 cannot be hydrogen or methyl if n=O and R1 is methyl. The compounds of the invention are valuable in the human and veterinary practice.
Bisphosphonic acids and esters