Cortical seizures can be suppressed with low frequency stimulation of the corpus callosum. An electrical stimulation signal with a frequency of less than 20 Hz can be applied to the corpus callosum in a patient's brain for a time. Hyper-excitability (indicative of seizure activity) of a target neural tissue within a cortex of the patient's brain that is activated by the corpus callosum can be suppressed. In fact, the hyper-excitability is reduced based on the stimulation.
SUPPRESSING SEIZURES WITH LOW FREQUENCY STIMULATION OF THE CORPUS CALLOSUM