Antidopaminergic agents having selective limbic activity, comprising (S)-enantiomers of aporphine compounds of either the following structures: <IMAGE> +TR <IMAGE> wherein R1 is lower alkyl, alkyl substituted lower alkyl, alkyl substituted cycloalkyl, lower alkenyl, alkyl substituted lower alkenyl, lower alkynyl, alkyl substituted lower alkynyl, phenyl lower alkyl, phenyl lower alkenyl, and phenyl lower alkynyl, and the following structure where R1 is above and R2 and R3 are hydrogen, methyl, or R1 <IMAGE> +TR <IMAGE> R1 is as above R4 is H, CH3 lower alkyl, or R1C0-where R1=CH3 or lower alkyl.
(+)-N-N-propylnorapomorphine and selective limbic activity