Induction of neuronal fate in neural stem cells or neural progenitor or precursor cells, or other stem cells, and enhancement of induction of a specific neuronal phenotype, and particularly to induction and enhancement of induction of a midbrain dopaminergic neuronal phenotype. Expressing a nuclear receptor of the Nurr1 subfamily above basal levels within the cell, and regulating GSK-3beta inhibition within the cell other than by means of a ligand for a Frizzled receptor.
METHODS AND MATERIALS RELATING TO ENHANCED PRODUCTION OF DOPAMINE NEURONS