Provided is a compound of a structure of formula (I) having a central nervous system disease treatment effect, which has the activity of a 5-HT2A receptor antagonist or an inverse agonist, has high 5-HT2A receptor selectivity, low cardiotoxicity, and good metabolic stability, and can be applied to treat some mental diseases (such as depression, anxiety disorders, psychiatric disorders, schizophrenia, insomnia, and autism) and central nervous system degenerative disorder (such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and dementia with Lewy bodies)-related or complicated mental disorders.
5HT2A RECEPTOR ANTAGONIST AND MEDICAL APPLICATION THEREOF