The present invention provides medicinal agents that are useful for the prevention or treatment of neuropathic pain which comprises as an active ingredient a ²2 adrenoceptor stimulant. In addition, the present invention provides formulations for the prevention or treatment of neuropathic pain such as painful diabetic neuropathy, postherpetic neuralgia, trigeminal neuralgia, or postoperative or traumatic chronic pain, that are characterized by the use in combination of an ± 2 -adrenoceptor stimulant and a ² 2 -adrenoceptor stimulant, or by containing a compound that has both ± 2 -adrenoceptor stimulation and ² 2 -adrenoceptor stimulation activities as an active ingredient or the like.
PREVENTIVE OR THERAPEUTIC AGENT FOR NEUROPATHIC PAIN