PROBLEM TO BE SOLVED: To provide an analysis method for comprehensively and quantitatively evaluating intercell protein interactions in a system in which cells derived from different individuals coexist, and identifying significant interactions and strongly interdependent signals.SOLUTION: The method for analyzing intercell protein interactions in the cells derived from two or more individuals, includes: a step for obtaining, and grouping by individual, expression profiles of genes in the micro-environment in which the cells derived from two or more individuals coexist; a step for selecting combinations of two proteins that may interact intercellularly; and a step in which, out of these protein combinations, when, in one individual of the two or more individuals, the expression level of the gene encoding one of the proteins is higher than in the other individuals, and when, in the individual other than the individual, the expression level of the gene encoding the other of the proteins is higher than the other individuals, then the interaction resulting from the protein combination is estimated, on the basis of the expression profiles, to be an interaction more significant than between the cells derived from the two or more individuals.
METHOD FOR ANALYZING INTERCELL INTERACTIONS