The present invention relates to an antibody or antigene-binding domain specifically-associated with polypeptide of potential-dependent voltage-gated ion channel, to use thereof for diagnosis of schizophrenia or bipolar disorder, to a set of anti-sense sequences inhibiting the ion channel expression, to a compound activating or inhibiting expression or activity of the ion channel of said polypeptide, to a pharmaceutical composition, comprising an antibody or a antigene-binding fragment, a set of anti-sense sequences or such compound and to a diagnostic kit for diagnosis of schizophrenia or bipolar disorder.
ANTIBODY OR ANTIGENE BINDING DOMAIN SPECIFICALLY ASSOCIATED WITH A POLYPEPTIDE OF POTENTIAL-DEPENDENT VOLTAGE-GATED ION CHANNEL