cDNAs encoding novel G protein-coupled receptor proteins originating in huma ns have been successfully isolated by uniquely extracting regions highly conserved in known G protein-coupled receptor proteins and effecting a screening with the use of probes corresponding thereto. Use of these G prote in- coupled receptor proteins makes it possible to screen ligands or candidate compounds for drugs capable of regulating the signal transduction from receptors.
NOVEL GUANOSINE TRIPHOSPHATE (GTP)-BINDING PROTEIN-COUPLED RECEPTOR PROTEINS, BG3