The present invention relates to a method of modulating activity by targeting a specific inhibitory neuron as a novel therapeutic target through an optogenetic technique, and a method of screening the novel therapeutic target. The present invention is based on a patch clamp technique in the field of electrophysiology which can measure electrical signals of brain nerve cells. The present invention can increase treatment efficiency by clarifying a treatment target.
Methods for recovery of synaptic plasticity using optogenetic technique in Alzhimers disease