A magnetic resonance CEST imaging sequence and apparatus based on a frequency stabilization module. The sequence comprises the following steps: firstly, in a frequency stabilization module, exciting a target slice by means of a small-flip-angle radio-frequency pulse, and collecting three rows of non-phase encoding k-space data; secondly, obtaining, by means of calculating the phase difference between the first row of non-phase encoding k-space data and the second row of non-phase encoding k-space data, a fine estimation value of a main magnetic field frequency drift; then, obtaining, by means of calculating the difference between the phase difference between the second row and the third row and the phase difference between the first row and the second row, a coarse estimation value of the main magnetic field frequency drift; then, determining a value of the main magnetic field frequency drift by means of comparing the difference between the coarse estimation value and the fine estimation value with a threshold value; then, adjusting the center frequency of the radio-frequency pulse according to a calculation result of the main magnetic field frequency drift to realize real-time correction of the main magnetic field frequency drift; and finally, performing conventional magnetic resonance CEST imaging. According to the method, real-time correction of a main magnetic field frequency drift during magnetic resonance CEST imaging is realized, and effective suppression of fat signals is ensured, thereby improving the performance of magnetic resonance CEST imaging.
MAGNETIC RESONANCE CEST IMAGING SEQUENCE AND APPARATUS BASED ON FREQUENCY STABILIZATION MODULE