Abstract The present disclosure provides an ultrafast dynamics imaging method and system based on single-molecule quantum coherence, which belongs to the cross field of quantum optics and medical science. An ultrafast dynamics imaging apparatus based on single-molecule quantum coherence includes four parts: preparation and control of a single molecule coherent state, femtosecond laser delay lock, excitation of a single molecule and fluorescence detection, and ultrafast dynamics imaging data extraction and processing. A relative delay of two laser beams is locked using a differential amplifier and a piezoelectric ceramic by monitoring an interferometric intensity of a combined laser beam. An electro-optic modulator is used to periodically change a relative phase of two laser beams to achieve the modulation of a population probability of a single molecule excitation state. A coherence factor is calculated to implement ultrafast dynamics imaging based on single-molecule quantum coherence. 106 107 129 -- ----- 112 108-- 11 1 10915 117 1 113 +- 2 :122 116 -.-- 120 31 1 101 102 103 - Laser light - Fluorescent emission - ---- Signal cable
Ultrafast dynamics imaging method and system based on single-molecule quantum coherence