Disclosed embodiments include a system and a method for determining intracranial pressure (ICP) of a subject that comprises: (a) applying transcranial Doppler (TCD) to determine the middle cerebral artery (MCA) velocity of the subject and estimating changes in the ICP continuously based on a functional mapping that relates arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV) to ICP, resulting in an estimated ICP trend; (b) generating a flash visual evoked potential (FVEP) on the subject, processing a detected FVEP signal and obtaining an estimated ICP; and (c) combining the estimated ICP trend from TCD CBFV and ABP with the estimated ICP obtained by signal processing of the detected FVEP signal to periodically correct the trend and obtain a non-invasive measure of ICP.
Method and system for non-invasive intracranial pressure monitoring