The invention relates to tetrahydropyridinyldibenzazepine derivatives of the formula I <IMAGE> (I) wherein R1 is a substituent selected from the group consisting of hydrogen, halogen, and lower alkyl; R2 is selected from hydrogen, and unsubstituted or hydroxy substituted lower alkyl or lower alkenyl; X is O, S, or CH2; Y is HC=CH or S; or a pharmaceutically acceptable salt thereof. These compounds are dopamine antagonists and are therefore useful for the treatment of psychotic disorders such as schizophrenia, schizophreniform disorder, delusional disorder, acute manic states, senile and presenile psychotic states, toxic psychoses, psychoactive-substance induced psychoses, symptoms of severe restlessness, hyperexcitability and anxiety, motor disorders, among which Tourette's disorder and Huntington's chorea, nausea and vomiting, hiccup and dizziness.
Tetrahydropyridinyldibenzazepine derivatives