THE INVENTION IS DIRECTED TO SUBSTITUTED BENZIMIDAZOL-2-ONES OF FOMULA I,WHEREIN A,X,Y, M, N,R1,R2,R3,R4,AND R5 ARE AS DESCRIBED IN THE SPECIFICATION,WHICH ARE USEFUL AS VASOPRESSIN RECEPTOR ANTAGONISTS OR NEUROPEPTIDE Y MODULATORS FOR TREATING CONDITIONS SUCH AS AGGRESSION,OBSESSIVE-COMPULSIVE DISORDERS, HYPERTENSION,DYSMENORRHEA,CONGESTIVE HEART FAILURE/CARDIAC INSUFFICIENCY,CORONARY VASOSPASM,CARDIAC ISCHEMIA, LIVER CIRRHOSIS,RENAL VASOSPASM,RENAL FAILURE, EDEMA,ISCHEMIA,STROKE,THROMBOSIS,WATER RETENTION,NEPHROTIC SYNDROME,CENTRAL NERVIOUS INJURIES,OBESITY.ANOREXIA,HYPERGLYCEMIA,DIABETES,ANXIETY,DEPRESSION,ASTHMA,MEMORY LOSS,SEXUAL DYSFUNCTION, DISORDERS OF SLEEP AND OTHER CIRCADIAN RHYTHMS,AND CUSHING'S DISEASE.
NOVEL SUBSTITUTED BENZIMIDAZOL-2-ONES AS VASOPRESSIN RECEPTOR ANTAGONISTS AND NEUROPEPTIDE Y MODULATORS