Systems, methods, and program instructions for quantifying neurophysiologic activity of a subject. A set of subject data representing a time series of neurophysiologic activity acquired by each of a multiplicity of spatially distributed sensors arranged to detect neural signaling in the subject is received. A time series of data obtained from each of the sensors is associated with a corresponding neural population within the brain of the subject. Interaction sets among at least two neural populations in the brain of the subject are determined based on a statistical analysis of a plurality of time series of data from a corresponding plurality of sensors. A plurality of regional groupings of neural populations is stored, with each one of the plurality of regional groupings encompassing a plurality of neural populations having a predefined relationship. An aggregated representation of cross-regional interactions between the neural populations across a selected plurality of the regional groupings is produced based on a selected subset of the interaction sets.
METHODS AND SYSTEMS FOR REGIONAL SYNCHRONOUS NEURAL INTERACTIONS ANALYSIS