A method for improving cognitive function in a subject suffering from or susceptible to MCI, Alzheimer's disease or other dementias, which subject is not homozygous for the APOE4 allele, comprising the steps of: (i) screening the subject to determine that the subject is not homozygous for the APOE4 allele; and then (ii) administering a safe and effective amount of a PPAR-gamma agonist to said subject.
PPAR-GAMMA AGONISTS FOR IMPROVEMENT OF COGNITIVE FUNCTION IN APOE4 NEGATIVE PATIENTS