In one aspect, methods of treating major depressive disorder (MDD) employing transcranial alternating current stimulation are described herein. A method of treating MDD in a patient comprises reducing alpha oscillations in one or more frontal brain regions of the patient via administering transcranial alternating current stimulation (tACS) to the patient at a frequency within the alpha frequency band.
Targeting Alpha Oscillations with Transcranial Alternating Current Stimulation (tACS) for the Treatment of Major Depressive Disorder (MDD)