Generalized pain syndrome is a disease of which a causal factor has not been defined yet and for which a therapeutic method has not been established yet.  Disclosed is a therapeutic or prophylactic agent for generalized pain syndrome.  The therapeutic or prophylactic agent for generalized pain syndrome comprises an LPA1 antagonist or an autotaxin inhibitor as an active ingredient.  The agent is preferably administered to the central nerve system.  Generalized pain syndrome is preferably fibromyalgia, chronic fatigue syndrome or irritable bowel syndrome.
THERAPEUTIC OR PROPHYLACTIC AGENT FOR GENERALIZED PAIN SYNDROME