The present invention provides polypeptides (termed 'egl-28 polypeptides') that modulate neurotransmitter- and psychostimulant-induced responses. The invention also provides methods of modulating such responses, as well as and anti-egl-28 antibodies. The invention encompasses related polynucleotides, vectors, host cells, production methods, and compositions. Moreover, the invention includes methods for prescreening or screening for test agents that modulate neurotransmitter and psychostimulant responses.
Novel mediator of neurotransmitter and psychostimulant responses