Systems and methods for performing online spike recovery from multi-channel electrophysiological recordings in accordance with various embodiments of the invention are described. One embodiment of a method of performing online spike recovery from multi-channel electrophysiological recordings includes: determining a set of waveform templates; continuously obtaining multi-channel electrophysiological recordings using a multi-channel electrode; and automatically performing online spike recovery from the multi-channel electrophysiological recordings using a processing system that performs a method for sparse signal recovery that continuously adjusts a processing buffer size based upon newly obtained multi-channel electrophysiological recordings.
Systems and Methods for Online Spike Recovery for High-Density Electrode Recordings using Convolutional Compressed Sensing