A system and method to detect abnormality of subjects directly from MRI k-space data are provided. The system includes: at least one computer hardware processor, at least one non-transitory computer-readable storage medium, and at least one computer program stored in the at least one non-transitory computer-readable storage medium and executable on the at least one computer hardware processor, wherein the at least one computer program includes: an acquisition module, configured to obtain target MRI k-space data by scanning a subject, wherein the target MRI k-space data are fully-sampled or undersampled or sparse MRI k-space data; a detection module, configured to obtain and output detection outcome from the target MRI k-space data using detection models; and a model training module, configured to train the detection models based on training data. Hence, the MRI scan time and related cost are reduced, and the accuracy of the detecting results is increased.
SYSTEM AND METHOD TO DETECT ABNORMALITY OF SUBJECTS DIRECTLY FROM MRI K-SPACE DATA