Disclosed are amide compounds represented by general formula (I). An example of a compound of formula (I) is 4-tert-Butyl-N-(5-(methylsulfonyl)pyridin-3-yl)-2-(6-trifluoromethyl)pyridin-3-yloxy)benzamide. The compounds of formula (I) are used to treat acute, chronic, neuropathic, or inflammatory pain, arthritis, migraine, cluster headaches, trigeminal neuralgia, herpetic neuralgia, general neuralgias, epilepsy or epilepsy conditions, neurodegenerative disorders, psychiatric disorders such as anxiety and depression, dipolar disorder, myotonia, arrhythmia, movement disorders, neuroendocrine disorders, ataxia, multiple sclerosis, irritable bowel syndrome, incontinence, visceral pain, osteoarthritis pain, postherpetic neuralgia, diabetic neuropathy, radicular pain, sciatica, back pain, head or neck pain, severe or intractable pain, nociceptive pain, breakthrough pain, postsurgical pain, cancer pain, stroke, cerebral ischemia, traumatic brain injury, amyotrophic lateral sclerosis, stress- or exercise induced angina, palpitations, hypertension, migraine, or abnormal gastro-intestinal motility.
AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS