PROBLEM TO BE SOLVED: To provide use of gelsoline for therapies of neurologic diseases such as multiple sclerosis, and use of gelsoline for diagnosis and observation of neurologic diseases and evaluation of therapies of neurologic diseases.SOLUTION: A method to characterize a risk profile of developing neurologic diseases of a subject in the future includes obtaining a gelsoline level of the subject, comparing the gelsoline level with a predetermined value, and characterizing the risk profile of developing a neurologic disease of the subject based on the gelsoline level compared to the predetermined value. A gelsoline level equal to or lower than the predetermined level indicates that the subject has a high risk of developing the neurologic disease, while a gelsoline level equal to or higher than the predetermined level indicates that the subject does not have a high risk of developing the neurologic disease.
USE OF GELSOLINE FOR THERAPIES OF MULTIPLE SCLEROSIS AND DIAGNOSIS OF NEUROLOGIC DISEASES