The invention relates to a device for stimulating neurons, comprising - a non-invasive stimulation unit for generating stimuli in a plurality of stimulation channels, the stimulation unit being designed such that the stimuli stimulate a neuron population in the brain and/or spinal cord of a patient via the stimulation channels in different locations, and - a control unit, which controls the stimulation unit during a first time interval and during a second time interval following the first time interval in different stimulation modes. The control unit controls the stimulation unit during at least 75% of the duration of the first time interval in a first stimulation mode such that the stimulation unit repeatedly generates sequences of stimuli and the order of the stimulation channels in which stimuli are generated within a sequence is constant for not more than 5 successively generated sequences and is then varied. The control unit controls the stimulation unit during at least 75% of the duration of the second time interval in a second stimulation mode such that the stimulation unit repeatedly generates sequences of stimuli and the order of the stimulation channels in which stimuli are generated within a sequence is constant for at least 25 successively generated sequences and is then varied. The intensity of stimuli in the first stimulation mode is lower than or equal to a predetermined stimulus intensity and the intensity of stimuli in the second stimulation mode is at least 1.3 times the predetermined stimulus intensity.
DEVICE AND METHOD FOR EFFECTIVE NON-INVASIVE TWO-STAGE NEUROSTIMULATION