PROBLEM TO BE SOLVED: To provide methods for use of and formulations of amisulpride, which is an atypical antipsychotic D2 receptor antagonist in the therapy of nausea, vomiting or retches.SOLUTION: For post-operative nausea and vomiting, or nausea and vomiting caused by chemotherapy, radiation or the like, the formulations are administered to a subject by various methods such as intravenous injection, intramuscular injection, subcutaneous injection, rectal administration, intranasal administration, buccal administration, oral administration, transdermal administration, sublingual administration or inhaled administration. Particularly utilized is an injectable formulation in a unit dosage form, comprising less than 50 mg of amisulpride {4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide}.SELECTED DRAWING: None
USE OF AMISULPRIDE AS ANTI-EMETIC