Systems and methods for magnetic resonance imaging (MRI) using side information for improved reconstruction are disclosed. In one aspect, in accordance with one example embodiment, images obtained using heteronuclei, such as Fluorine-19 (19F), can be reconstructed using one or more methods to provide improved resolution and detail. The system can use anatomical proton MRI scans. The system can use multiple smoothing techniques to improve the signal-to-noise ratio (SNR). The system can also use weighted smoothing using information from anatomical proton MRI scans to improve resolution.
Systems and methods for regularized reconstructions in MRI using side information