Methods and kits used for determining predisposition and/or diagnosis of schizophrenia, bipolar disorder, breast cancer and colorectal cancer using genotypes in the COMT locus are disclosed. Also disclosed are methods and drugs for treating these disorders. Further disclosed are methods and kits useful for prediction drug responsiveness towards mental disorders drugs, and more specifically towards schizophrenia drugs.
ASSOCIATION OF SNPS IN THE COMT LOCUS AND NEIGHBORING LOCI WITH SCHIZOPHRENIA, BIPOLAR DISORDER, BREAST CANCER AND COLORECTAL CANCER