The present invention provides methods for identifying genes involved in memory consolidation, and for identifying agents which effect memory consolidation in a mammal. These methods preferably use (1) non-human mammal s which have been manipulated to create at least partial disruption of fornix- mediated afferant signalling to the hippocampus, said disruption affecting memory consolidation or (2) non-lesioned mammals which have been subjected t o a learning and memory test to provide a learned behavior in the mammal.</SDO AB>
METHODS AND COMPOSITIONS FOR REGULATING MEMORY CONSOLIDATION