A method for preparing a non-human mammalian model of neuronal dendritic dysplasia in extensive brain regions, comprising the following steps: exposing a non-human mammal in a low-oxygen condition for 30-40 min to obtain an animal model of neuronal dendritic dysplasia in extensive brain regions, wherein in the low-oxygen condition, the oxygen concentration (volume ratio) drops from 10-20% to 1-5%. The animal model can be applied to study neuronal dendritic dysplasia in extensive brain regions, and can be applied to screening and testing tests of particular drugs.
PREPARATION AND APPLICATION OF ANIMAL MODEL OF NEURONAL DENDRITIC DYSPLASIA IN EXTENSIVE BRAIN REGIONS