PURPOSE: A composition for treating and preventing liver diseases is provided to measure expression and phosphorylation level of TM4SF5 expression-associated signal transduction proteins. CONSTITUTION: A composition for diagnosing liver diseases contains a material for measuring TM4SF5(transmembrane 4 L six family member 5) or four-transmembrane L6 superfamily member 5 protein level. The material is an antibody which specifically recognizes TM4SF5. The TM4SF5 protein is a polypeptide having an amino acid sequence of sequence number 2. A kit for diagnosing liver diseases contains the composition. A pharmaceutical composition for preventing or treating liver diseases contains the materials.
Composition for Diagnosing, Treating and Preventing Hepatic Disease