A method for the detection of autoantibodies comprises detecting autoantibodies in a sample from an individual using label free electrochemical impedance spectroscopy. In one aspect, the method is a method for the diagnosis or monitoring of Parkinson's disease comprising detecting alpha-synuclein autoantibodies in a sample from an individual using electrochemical impedance spectroscopy. We also describe electrodes for use in these methods.
Method For Detecting Autoantibodies