A system and method for imaging includes applying an RF excitation pulse to a region-of-interest (ROI) in the presence of a first slice selective gradient and applying a readout gradient to acquire a echo signal from the ROI, wherein a time between the RF excitation pulse and the echo signal define an echo time (TE). A saturation module is applied to the ROI including an RF pulse configured to provide a TE-independent steady state and enforcing a predetermined time period (TR0) selected to elapse between the RF pulse of the saturation module and a subsequent application of the RF excitation pulse during repetitions of the above-described portions of the process. An image of the ROI is reconstructed using the acquired echo signals, for example, a T2-weighted image having reduced underestimations of T2 that plague traditional T2-weighted imaging processes using a short TR with a spin-echo (SE) pulse sequence.
System and method for controlling apparent timing dependencies for T2-weighted MRI imaging