A method of stimulating a patient's brain comprising delivering an electrical stimulation to at least one electrode causing stimulation of a person's anterior cingulum bundle, or especially causing stimulation of a person's dorsal portion of an anterior cingulum bundle resulting in emotional change(s) in a patient comprising one or more of the following: anxiolysis, mirth, analgesia, improved affective tone, enhanced cognitive focus, increased well-being, engagement, or optimism. Further embodiments contemplate an apparatus. Further embodiments contemplate two implanted electrodes within the dorsal portion of the anterior cingulum bundle spaced between about 5 mm and 8 mm apart, having electrical stimulation parameters of between about 1.0 mA and about 3.5 mA, between about 100 Hz to about 150 Hz, and having a pulse width of between about 100 microseconds to about 200 microseconds.
Anxiolysis without sedation: awake craniotomy facilitated by continuous direct stimulation of cingulum bundle