A method and a system create an age-specific quantitative atlas for a biological object. The method includes obtaining a quantitative map of the biological object for each subject of a healthy subject population, generating an age-specific initial map for the biological object using a weighted mean, and spatially registering each of the quantitative maps on the age-specific initial map. The generating and registering steps are repeated iteratively until reaching a first predefined alignment threshold between all spatially registered quantitative maps. The new age-specific initial map obtained is stored at the end of the iterative process of the repeating step as the age-specific quantitative atlas for a biological object characterized by the specific age.
AGE-SPECIFIC IMAGE ATLAS