A bio-sensing nanodevice comprising a stabilized biologically-derived G-protein coupled receptor -the olfactory receptor- on a support is disclosed. A real time receptor-ligand binding detection method, an odorant delivery system and an odorant recognition program are further disclosed. The biologically-derived G-protein coupled receptor can be stabilized on nanotechnology using a surfactant peptide. Methods of fabricating hOR17-4 olfactory receptor are also provided.
BIO-SENSING NANODEVICE