The present invention provides,in a method of magnetic resonance imaging of cerebral blood flow using pulse sequence of rapid gradient-echo method, wherein the pulse is RF pulse having slice gradient, read gradient and phase-encode gradient, the improvement comprises giving the RF pulse with flip angle of between 45 and 60 degrees, and adding an additional gradient to each of the slice gradient, read gradient and phase-encode gradient, thereby diffusing and refusing proton spin in the cerebral blood flow. This method makes it possible to clearly image very slight changes in the blood flow in the brain, and permits diagnosis of diabetes by detecting the increase in the blood flow in a specific brain region after systemic administration of insulin.
MAGNETIC RESONANCE IMAGING OF CEREBRAL BLOOD FLOW AND DIAGNOSIS OF DIABETES