PROBLEM TO BE SOLVED: To provide therapeutic agents effective for CGRP related disorders, including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD).SOLUTION: Compounds having CGRP receptor antagonistic action represented, e.g., by the formulas in the figure are used as the therapeutic agents for the diseases.
CGRP RECEPTOR ANTAGONISTS