To provide an animal showing chronic abnormality in cognitive behaviors closely similar to schizophrenia, an animal showing schizophrenia-like abnormality in cognitive behaviors is constructed by administering a specifi c protein factor inhibiting the brain function development to an immature anim al in the development stage. The abnormality in cognitive behavior observed in this animal, which is closely similar to schizophrenia, is useful in developing remedies and diagnostics for schizophrenia.
A SCHIZOPHRENIC MODEL ANIMAL WITH SENSORIMOTOR AND BEHAVIORAL ABNORMALITIES AND A METHOD FOR PREPARING THE SAME