Prevention or treatment of pain (especially pain associated with prostate cancer) by administration of an endothelin antagonist, more particularly of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide or a salt thereof, optionally in combination with a narcotic.
METHOD FOR PREVENTING OR TREATING PAIN BY ADMINISTERING AN ENDOTHELIN ANTAGONIST