The present invention relates to a composition for diagnosing mild cognitive impairment for non-invasive in-vitro diagnosis and a kit including the same and, more specifically, to a biomarker composition for diagnosing mild cognitive impairment including S100A9 protein or a gene encoding the same using an isolated nasal discharge sample which is a non-invasive biological sample, a kit for diagnosing mild cognitive impairment including the same, and a method for providing information required for the diagnosis of mild cognitive impairment. According to the present invention, the biomarker composition and the kit can diagnose mild cognitive impairment even with a small amount of a nasal discharge sample, thereby being excellent in terms of simplicity and economy. In addition, the biomarker composition and the kit can discriminate between a patient group with Alzheimer's disease and patients with mild cognitive impairment, thereby being effectively used to establish a treatment plan for mild cognitive impairment.
Biomarker composition for diagnosis of Mild cognitive impairment using nasal samples and method of diagnosing Mild cognitive impairment using the same