The invention discloses an application of an isoflavone compound to preventing or treating neurodegenerative diseases. The isoflavone compound J37941 can dose-dependently inhibit the activity of acetylcholin esterase of the cell at the safe dose, protects the nerve cell, alleviates the oxidative stress injury of the nerve cell, regulates the neuroinflammation, and has stronger effects of inhibiting the activities of both acetylcholinesterase and butyrylcholine esterase; the result of the animal experiment proves that the J37941 is relatively low in toxicity, can penetrate through the blood brain barrier, obviously improve the mouse dementia caused byscopolamine, and strengthens the learning and memorial functions. A large number of preclinical study results prove that the J37941 is expected to become a medicine for preventing and/or treating learning and memory disorder and the alzheimer disease.
Application of isoflavone compound to preventing or treating neurodegenerative diseases