ANTIPSYCHOTIC COMPOSITIONS CONTAINING DIOXOPIPERIDINE DERIVATIVES Phenyl-3-aminoalkyl-4-methyl-2,6-dioxopiperidines of the Formula I <IMG> (I) wherein: R1 represents hydrogen or C1-C4 alkyl; n is 1 or 2; R2 represents hydrogen or methyl, provided that one R2 is hydrogen when n is 2; R3 represents hydrogen or C1-C2 alkyl; R4 represents C1-C2 alkyl; R5 and R6 independently represent hydrogen or methyl; m is 0 to 3; and each Y is in a meta or para position and independently represents hydroxy, C1-C2 alkoxy, C1-C2 alkyl, C1-C2 hydroxyalkyl, halogen, or trifluoromethyl, provided that hydroxy and alkoxy are not in the para position, and pharmacologically acceptable salts thereof have antiposychotic activity without sedative side effects. They are particularly useful in the treatment of schizophrenia. The presently preferred compound is 3-(3'methoxyphenyl)-3-(3'-N,N-dimethylaminopropyl) -4,4-dimethyl-2,6-dioxopiperidine (AGN 2979).
ANTIPSYCHOTIC COMPOSITIONS CONTAINING DIOXOPIPERIDINE DERIVATIVES