<P>PROBLEM TO BE SOLVED: To provide a method for diagnosing or predicting sensitivity to a mental disorder, by which the participation of disrupted-in schizophrenia-1 (DISC1) in the mental disorder can be elucidated. <P>SOLUTION: This method for diagnosing or predicting fragility to a mental disorder such as bipolar disorder in an individual comprises confirming the molecular diversity and/or intracellular distribution of the DISC1 in a cell from the individual. In addition, the risk haplotype of the DISC1 for the mental disorder is also provided. Thereby, the method can be utilized for screening a medicine for treating the mental disorder. <P>COPYRIGHT: (C)2005,JPO&NCIPI 
METHOD FOR DIAGNOSING OR PREDICTING SENSITIVITY TO MENTAL DISORDER