To provide an in-vitro early detection method of potential inflammation especially related to implantation rejection reaction.SOLUTION: An in-vitro detection and/or observation method of neurodegenerative disease for measuring a kynurenine level in salvia or plasma. An in-vitro detection and/or observation method of neurodegenerative disease for quantitatively measuring a kynurenine level in salvia. An in-vitro detection and/or observation method of neurodegenerative disease in which the neurodegenerative disease is selected from a group made up of Alzheimer disease, blood vessel type dementia, Parkinson disease, postoperative cognitive impairment, and depression.SELECTED DRAWING: None
IN-VITRO EARLY DETECTION METHOD FOR POTENTIAL INFLAMMATION ESPECIALLY RELATED TO IMPLANTATION REJECTION REACTION, NEURODEGENERATIVE DISEASE, OR DEPRESSION