PROBLEM TO BE SOLVED: To provide medicaments for treating pain, preferably neuropathic pain, more preferably neuropathic pain due to lumbar radiculopathy in subjects suffering from depression and/or anxiety.SOLUTION: Disclosed is tapentadol for use in treatment of pain in a subject suffering from depression and/or anxiety, and/or in treatment or prevention of depression and/or anxiety, with the proviso that tapentadol is not administered in combination with an AMPA receptor antagonist, and further tapentadol is administered as a sole pharmacologically active ingredient.SELECTED DRAWING: None
TAPENTADOL FOR PREVENTING AND TREATING DEPRESSION AND ANXIETY