PROBLEM TO BE SOLVED: To provide methods of preventing or treating cardiac ischemia/reperfusion injury in a mammalian subject.SOLUTION: The methods provide administering aromatic-cationic peptides in effective amounts to prevent or treat an anatomic zone of no re-flow in mammalian subjects. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof.SELECTED DRAWING: Figure 1
METHODS FOR THE PREVENTION OR TREATMENT OF NO-REFLOW FOLLOWING ISCHEMIA/REPERFUSION INJURY