A deep brain stimulation apparatus according to the present invention comprises: a stimulation unit for applying an electric stimulus to a brain; a light source unit for injecting light in the brain; a plasmonic nono-particle which, when the brain releases a neurotransmitter by the electric stimulus, comes into contact with the neurotransmitter to enable surface-enhanced Raman scattering (SERS); an optical detection unit which includes the plasmonic nano-particle and, when the light injected by the light source is scattered by the neurotransmitter which has come into contact with the plasmonic nano-particle, detects the scattered light; a signal processing analysis unit for converting a light signal from the optical detection unit to an electric signal; and a control unit for receiving an analysis signal from the signal processing analysis unit so as to control the stimulation unit.
DEEP BRAIN STIMULATION APPARATUS AND DEEP BRAIN STIMULATION METHOD ON BASIS OF SURFACE-ENHANCED RAMAN SPECTROSCOPY