The invention relates to the identification of flt1 gene function in zebrafish, which is required for sprouting angiogenesis, and uses of flt1 mutant zebrafish in genetic and compound screens to identify members of the flt1 signaling pathway and compounds that affect sprouting angiogenesis.
IDENTIFICATION OF THE FLT1 GENE REQUIRED FOR ANGIOGENESIS IN ZEBRAFISH, AND USES THEREOF