Disclosed in the present invention are a method and device for non-mark all-optical nerve regulation and imaging. Infrared laser pulses are used for stimulating nerve activity, and OCT is used for collecting an optical scattered signal triggered by the nerve activity, so as to implement non-mark all-optical nerve regulation and imaging. The method specifically comprises: aiming an infrared laser at a brain target region; injecting laser pulses of a certain time sequence; performing synchronous scanning imaging on the target region by using OCT; analyzing a relative change of an OCT scattered signal compared with the condition prior to laser stimulation; and obtaining a brain function signal based on OCT to synchronously implement nerve regulation and imaging. According to the present invention, nerve regulation and imaging can be synchronously developed, a crosstalk phenomenon of a regulation/imaging channel is avoided, a contrast medium and virus transfection are not needed, and regulation and imaging of a tissue deep region can be implemented by means of a near infrared band.
METHOD AND DEVICE FOR NON-MARK ALL-OPTICAL NERVE REGULATION AND IMAGING