The present invention provides a real time closed circuit brain-artificial neural network interface device which generates an artificial neural network reproducing an input received from a brain-neural network by a real nerve cell in a real brain information processing and can connect the artificial neural network and a real brain, and a method thereof. A brain nerve stimulation interface device comprises: a signal acquiring part acquiring a nerve signal through at least one fine electrode; an analyzing part analyzing an acquired nerve signal potential to generate a trigger according to at least one of a synapse stimulation type and an ignition activity; an artificial neural network model part generating different synapse stimuli based on an artificial neural network model according to the generated trigger; and a signal delivering part delivering the generated synapse stimulation to the nerve cell.
- Real-time closed-loop brain-artificial neural network interface apparatus and method