Systems and methods are provided for controlling predictive medical monitoring. A non-linear-predictive-guide model estimates a patient parameter that is used as a guide in a deep neural network for improving accuracy of estimation by the deep neural network. The guide model generates a guiding first estimated patient parameter based on the guide model and patient input data. The deep neural network generates a second estimated patient parameter based on the deep neural network, the patient input data, and the guiding first estimated patient parameter. The deep neural network includes an input layer that receives the guiding first estimated patient parameter, and hidden layers including respective artificial neurons configured to perform a linear or nonlinear transformation on output of at least one artificial neuron from an adjacent layer in the deep neural network. An output layer receives at least one output from a hidden layer.
MODEL GUIDED DEEP LEARNING APPROACH TOWARDS PREDICTION OF PHYSICAL SYSTEM BEHAVIOR