A method of treating symptoms of schizophrenia includes enterically administering to a subject a pharmacological agent that inhibits presynaptic glutamate release, modulates postsynaptic glutamate response, or both. Embodiments herein relate to the use of dextromethorphan, and in particular dextromethorphan combined with quinidine, in reducing symptoms of schizophrenia.
METHOD OF TREATING SCHIZOPHRENIA