[' ', ' ', 'ay', 'G.', 'Saccomanne', '$0.05', '3.26', 'Renge', '37.26', 'to', '70.50', 'years', ':', '(33cases', '}:', '57', '56.79', '56', '56.57', '(yu', '1.22.', 'Range', '38.66', '1070.34', 'years', '4.24:', 'Range:', '34.18', 'tip', '62.66years', '$1.33', '   ', 'Age', 'w', '°', 't', '2.89', 'Range', '33', '85', 'to', '59.58', 'years', '68.44:', '[Squamous', 'cell', 'Metaplasia-mild', 'atypia', 'Wt', 'wee', 'tt', 'Moderate', 'atypic', '4', 'H—', 'I', 'U', 'markedi', 'atypia', 'WH', 'Carcinoma', 'inisity', '[J]', 'Invasive', 'carcinoma', 'Fig.', '4.', 'Development', 'of', 'carcinoma', 'of', 'the', 'lung.', 'Average', 'case', '(epidermoid', 'carcinoma)', 'Gross', '(personal', 'communication),', 'using', 'the', 'T', 'cell', 'analysis.', 'rosette', 'inhibition', 'test.', 'and', 'phytohemagglutinin', 'test', 'in', 'patients', 'with', 'squamous', 'cell', 'metaplasia.', 'showed', 'thatisome', 'degree', 'of', 'immunological', 'impairment', 'was', 'evident.', 'in', 'moderate', 'atypia,', 'but', 'more', 'pronounced', 'in', 'marked', 'atypia.', 'carcinoma', 'in', 'situ,.and', 'invasive', 'carcinoma.', 'The', 'cellular', 'change', 'noted', 'in', 'the', 'Progression', 'of', 'atypia', 'to', 'neoplasia', 'is.', 'probably', 'a', 'complex', 'mechanism', 'visible', 'cytologically', 'in', 'shed', 'metaplastic', 'cells', 'from', 'the', 'lung,', 'and', 'is', 'possibly', 'the', 'product', 'of', 'an', 'altered', 'systemic', 'immunological', 'surveillance', 'Process:', 'This.certainly', 'necessitates', 'more', 'in-depth', 'research,', 'notionly', 'into', 'the', 'chemistry', 'of', 'these', 'abnormal', 'cell:', 'changes,', 'but', 'also', 'into', 'how', 'this', 'relates', 'to', 'the.', 'body’s', 'immune', 'system.', 'Further,', 'studies', 'on', 'the', 'significance', 'of', 'squamous', 'cell', 'metaplasia', 'are', 'presently', 'in', 'Progress.', 'A', 'retrospective', 'computerized', 'study', 'is', 'under', 'way.', 'which', 'will', 'assess', 'the', 'significance', 'of', 'moderate', 'atypical', 'squamous', 'cell', 'metaplasia', 'when', 'found', 'in', 'uranium', 'miners.', 'The', 'computer', 'analysis', 'will', 'relate', 'this', 'degree', 'of', 'atypia', 'to', 'numerous', 'factors', 'such:', 'as', 'age.', 'mining', 'experience', '(WLM', 'accumulation),', 'smoking', 'history,', 'and', 'other', 'ej', 'OfTEIzpz0,']