['FIRST', 'DRAFT', "'", 'The', 'mean', 'daily', 'number', 'of', 'puffs', '(MPD)', 'made', 'by', 'the', 'animals', 'was', 'signi-', 'ficantly', '(F', '=', '41.89,', 'df', '=', '1,9,', 'p', '<', '.001)', 'greater', 'when', 'they', 'were', 'smoking', '1A3', 'cigarette', '(413)', 'than', 'it', 'was', 'when', 'they', 'were', 'smoking', 'the', 'Code', '14', 'cigarette', '(230).', 'The', 'MPD', 'was', 'also', 'significantly', '(F', '=', '35.95,', 'df', '=', '1,9,', 'p', '<', '.001)', 'greater', 'when', 'the', 'animals.', 'used', 'the', '1.27', 'cm', 'switch;', 'the', 'mean', 'MPD', 'values', 'were', '408', 'for', 'the', '12.7', 'cm', 'suieeh', 'and', '235', 'for', 'the', '2.54', 'cm', 'switch.', 'These', 'effects', 'are', 'primarily', 'due', 'to', 'the', 'difference', 'in', 'draw', 'resistance', 'of', 'the', 'two', 'cigarettes', 'since,', 'for', 'any', 'given', 'puff', 'volume', '(i.e.,', 'switch', 'sensitivity', 'x', 'duration', 'combination),', 'the', 'Code', '14', 'cigarette', 'is', 'consumed', 'in', '39%', 'fewer', 'puffs', 'than', 'is', 'the', '1A3', 'cigarette.', 'As', 'would', 'therefore', 'be', 'expected,', 'the', 'mean', 'daily', 'water', '(MDW)', 'intake', 'was', 'also', 'significantly', 'affected', 'by', 'both', 'switch', '(F', '=', '57.77,', 'df', '=', '1,9,', 'p', '<', '.001)', 'and', 'cigarette', '(F', '=', '35.73,', 'df', '=', '1,9,', 'p', '<', '.001)', 'type.', 'The', 'animals', 'received', 'an', 'average', 'of', '314', 'ml', 'per', 'day', 'while', 'smoking', 'the', '1A5.', 'and', '178', 'ml', 'per', 'day', 'while', 'smoking', 'the', 'Code', '14;', 'they', 'also', 'averaged', '309', 'ml', 'per', 'day', 'while', 'on', 'the', '1.27', 'cm', 'swireh', 'and', '184', 'ml', 'when', 'on', 'the', '2.54', 'cm', 'switch.', 'Finally,', 'as', 'would', 'also', 'be', 'expected,', 'the', 'body', 'weight', 'of', 'the', 'animals', 'was', 'significantly', 'influenced', 'by', 'these', 'large', 'differences', 'in', 'water', 'intake.', 'The', 'switch', 'x', 'cigarette', 'inter-', 'action', 'term', 'was', 'significant', '(F', '=', '75.73,', 'df', '=', '1,9,', 'p', '<', '.001),', 'and', 'the', 'four', 'cell', 'means', 'are', 'presented', 'in', 'Figure', '9.', 'The', 'mean', 'body', 'weight', 'while', 'smoking', '1A3', 'cigarettes.', 'was', '13.75', 'kg.', 'However,', 'the', 'combination', 'of', 'the', 'low', 'draw', 'resistance', '(i.e.,', 'few', 'puffs', 'and', 'therefore', 'little', 'water)', 'Code', '14', 'and', 'the', '2.54', 'cm', 'threshold', '(i.e.,', 'large', 'puffs)', 'pressure', 'switch', 'led', 'to', 'very', 'low', 'water', 'intakes,', 'and', 'a', 'drop', 'in', 'body', 'weight', '(from', '13.75', 'kg', 'to', '13.17', 'kg)', 'occurred', 'as', 'the', 'animals', 'worked', 'the', 'Code', '14', 'cigarette', 'with', 'the', '1.27', 'and', '2.54', 'cm', 'switches,', 'respectively.', '63', 'F680200000']