['CONFIDENTIAL', 'PROJECT', 'NUMBER:', '2501', 'PROJECT', 'TITLE', ' :', 'Smoke', 'Chemistry', 'PROJECT', 'LEADER:', '_', 'R.', 'A.', 'Comes', 'PERIOD:', 'COVERED', ':', '=', 'March,', '1991', 'I.', 'SIDESTREAM', 'SMOKE', 'CHAMBER', 'A.', 'Objective:', 'Operate', 'an.', 'environmentally:', 'controlled.', 'chamber', 'to', 'measure:', 'selected!', 'components', 'of', 'sidestream', 'smoke.', 'B.', 'Results:', 'The', 'chamber', 'study', 'comparing', 'the', 'new', 'single', 'wrapped!', 'Super', 'Slims:', 'prototype:', 'with', 'the', 'current', 'production:', 'double', 'wrapped!', 'model', 'has', 'been:', 'completed.', 'Virginia', 'Slims.', 'Super', 'Slims.', 'and', 'Capri', 'cigarettes', 'saved', 'frozen:', 'since', 'they', 'were', 'investigated', 'in', '1989', 'were:', 'also:', 'run', 'in', 'the:', 'chamber.', 'Results', 'for', 'all', 'analyses', 'were', 'in’', 'very', 'good', 'agreement', 'between', 'all', 'Super', 'Slims', 'models.', 'Aerosol', 'data:', 'showed.', 'that', 'the:', 'sidestream', 'smoke', 'from', 'the', 'single', 'wrap', 'model', 'has', 'the', 'same', 'aerosol', 'properties', 'as', 'the', 'double', 'wrap:', 'model.', 'In', 'addition,.', 'the', 'sidestream.smoke:', 'from', 'the', 'Super', 'Slims.', 'models', 'have', 'smaller', 'size', 'distributions.', 'than', 'that.', 'from', 'the', 'sidestream', 'smoke:', 'of', 'the', 'Capri', 'and.', 'IM13', 'cigarettes.', 'Memos', 'have:', 'issued', 'detailing:', 'these', 'studies.', 'Also', 'included', 'is', 'the', 'data.', 'from', 'the', 'smokKings.', 'on', 'the', 'prototype', 'CORESTA', 'apparatus', 'to', 'generate:', 'mainstream:', 'and', 'sidestream', 'TPM', 'and', 'puff', 'count', 'for', 'the', 'two', 'Super', 'Slims:', 'models.', 'Multiple', 'chamber', 'runs', 'have', 'been', 'carried', 'out', 'in', 'conjunction', 'with', 'the', 'BCR', 'Division:', 'as!', 'a', 'continuation:', 'of', 'their', 'studies.', 'on', 'the', 'collection', 'and', 'quantitative.', 'analysis', 'of', 'compounds', 'of', 'interest.', 'Progress', 'has.', 'been', 'made', 'in', 'the', 'new', 'study', 'to', 'monitor.', 'analytical', 'sidestream', 'parameters:', 'in', 'the', 'sidestream', 'chamber', 'in', 'conjunction', 'with', 'sidestream', 'subjective', 'evaluations.', 'Engineering', 'drawings', 'are', 'nearing', 'completion', 'for', 'modification', 'of', 'the', 'chamber', 'door', 'to:', 'permit', 'subjective', 'evaluations.', 'simultaneous', 'with', 'the', 'analytical', 'data', 'collection.', 'New', 'ports', 'for', 'the', '30-port', 'Borgwaldt', 'smoker', 'have:', 'been', 'designed', 'and', 'fabricated', 'by.', 'the:', 'shop', 'to', 'accommodate', 'the', '24.0', 'mm:', 'circumference', 'cigarette', 'models', 'produced!', 'for', 'this.', 'work..', 'The', 'initial', 'subjective.', 'study', 'of', 'sidestream', 'smoke', 'being', 'carried', 'out.', 'with', 'ARD', 'and', 'PED', 'personnel’', 'has’', 'shown', 'considerable', 'promise', 'in', 'the', 'ability', 'of', 'untrained', 'panelists', 'to', 'detect', 'differences', 'between', 'the', 'gas:', 'phases', 'of', 'different', 'models', 'as', 'well', 'as', 'differences', 'between.', 'gas', 'phase', 'and.', 'whole.smoke.', 'These:', 'studies.', 'will', 'continue', 'until', 'chamber', 'modifications.', 'have', 'been', 'completed!', 'Additional', 'attempts', 'to', 'prepare:a', '3-vinylpyridine', 'release', 'agent', 'to', 'study.', 'this', 'compound', 'for', 'potential', 'use', 'as', 'a', 'marker', 'for', 'sidestream', 'gas:', 'phase.', 'constituents.', 'have', 'been', 'unsuccessful.', 'However,', 'it', 'has', 'been', 'determined’', '(by:', 'gc/ms):', 'that.', 'the.', 'compound.', 'is', 'present', 'in', 'sidestream:', 'smoke', 'as', 'one', 'of', 'the', 'larger', 'peaks', 'and', 'that', 'it', 'is:', 'present', 'in', 'both', 'concentrated', 'and', 'unconcentrated', 'XAD', 'chamber', 'nicotine.', 'extracts', 'of', 'sidestream', 'smoke.', 'Based', 'on.', 'the', 'known.', 'retention:', 'time', 'of', 'ethylpyridine', 'and', 'its', 'retention', 'time', 'relative', 'to', '3-vinylpyridine,', 'the', 'latter', 'should', 'be', 'quantifiable', 'using', 'NPD:', 'detection', 'in', 'the', 'same', 'analysis', 'as', 'for', 'chamber', 'nicotine.', 'C91-01657', 'ESTeceeco]e']