['505693717', 'PRODUC]', 'An', 'Experiment', 'to', 'Determine', 'the', 'General', 'Relationship', 'Between', 'Cigarette', 'Smoke', 'Yields', 'using', 'an', 'Alternative', 'Puffing', 'Regimen', '(55/30/2)', 'and', 'the', 'Standard', 'FTC', 'Method', 'Summary', 'An', 'experiment', 'has', 'been', 'conducted', 'in', 'four', 'laboratories', 'to', 'determine', 'the', 'general', 'relationship', 'between', '(a)', 'smoke', 'yields', 'when', 'cigarettes', 'are', 'smoked', 'with', 'an', 'alternative', 'puffing', 'regimen,', 'and', '(b)', 'smoke', 'yields', 'when', 'cigarettes', 'are', 'smoked', 'with', 'the', 'standard', 'FTC', 'method', 'protocol.', 'The', 'alternative', 'regimen', 'consisted', 'of', 'a', 'larger', 'puff', 'volume', '(55', 'cc)', 'than', 'the', 'standard', 'method,', 'with', 'puffs', 'taken', 'more', 'frequently', '(a', 'puff', 'taken', 'every', '30s).', 'The', 'puff', 'duration', '(2', 's)', 'was', 'identical', 'for', 'both', 'regimens.', 'Smoke', 'yields', 'from', 'fifty', 'cigarette', 'brand', 'styles', '(46', 'commercial', 'brands', 'and', 'four', 'University', 'of', 'Kentucky', 'reference', 'cigarettes)', 'were', 'evaluated', 'in', 'each', 'laboratory.', 'Brand', 'styles', 'studied', 'were', 'selected', 'to', 'provide', '_', 'comprehensive', 'insight', 'into', 'the', 'smoke', 'yield', 'relationship', 'as', 'defined', 'by', 'the', 'current', 'marketplace.', 'A', 'wide', 'range', 'of', 'brand', 'styles', 'representing', 'different', 'cigarette', 'lengths,', 'circumferences,', 'filter', 'types,', 'price', 'tier,', 'pack', 'styles,', 'menthol', 'inclusion', 'and', 'FTC', '“tar”', 'yields', 'was', 'evaluated.', 'Based', 'on', '1,840', 'results', '(10', 'ports', 'each', 'of', '41', 'commercial', 'brand', 'styles', 'chosen', 'independently', 'by', 'each', 'laboratory,', 'plus', '10', 'ports', 'each', 'of', '5', 'commercial', 'brand', 'styles', 'provided', 'to', 'each', 'laboratory', 'from', 'a', 'single', 'purchase,', 'times', 'analysis', 'in', '4', '.', 'laboratories),', 'the', 'following', 'empirical', 'relationships', 'were', 'observed', 'between', 'smoking', 'regimens:', '55/30/2', '"Tar"', '=', '-0.0237*(FTC', '"Tar")*', '+', '2.5042*(FIC', '"Tar")', '+', '1.9394;', 'R’', '=', '0.9819', '55/30/2', 'Nicotine', '=', '-0.1192*(FTC', 'Nicotine)’', '+', '2.0529*(FTC', 'Nicotine)', '+', '0.2650', 'R?=0.9724', '©', '-', '§5/30/2', 'CO', '=', '-0.0051*(FTC', 'COS', '+', '1.4718*(FTC', 'CO)', '+', '6.6969', 'R2', '=', '0.9186', '.', '(Note', 'that', 'all', 'coefficients', 'are', 'expressed', 'with', 'a', 'generous', 'number', 'of', 'significant', 'figures.)', 'Regression', 'analysis', 'demonstrated', 'that', '“tar,”', 'nicotine', 'and', 'carbon', 'monoxide', 'data', 'from', 'the', 'two', 'puffing', 'tegimens', 'can', 'each', 'be', 'related', 'by', 'a', 'simple', 'quadratic', 'function.', 'These', 'quadratic', 'functions', 'can', 'be', 'used', 'to', 'predict', '55/30/2', 'smioke', 'yields', 'from', 'FTC', 'smoke', 'yield', 'data.', ' ', ' ', 'ED', 'FROM', 'BéW', 'WEB', 'SITE', ' ', ' ', ' ', ' ', ' ', ' ', ' ']