Gallbladder cancer | Ireland| PDF | PPT| Case Reports | Symptoms | Treatment

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Gallbladder Cancer

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  • Introduction
    Gallbladder cancer is cancer that begins in the gallbladder. Gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder stores bile, a digestive fluid produced by your liver. But most gallbladder cancers are discovered at a late stage, when the prognosis is often very poor. Gallbladder cancer is difficult to diagnose because it often causes no specific signs or symptoms.

  • Pathogenesis
    Gallbladder cancer arises in the setting of chronic inflammation. In the vast majority of patients, the source of this chronic inflammation is cholesterol gallstones. The presence of gallstones increases the risk of gallbladder cancer 4 to 5 fold. These causes include primary sclerosing cholangitis, ulcerative colitis, liver flukes, chronic Salmonella typhi and paratyphi infections, and Helicobacter infection.

  • Treatment
    Surgery is an important treatment for gall bladder cancer. If you have early gall bladder cancer, it may be removed using an open cholecystectomy or a laparotomy. Radiotherapy treats cancer by using high energy x-rays to destroy the cancer cells. Chemotherapy is the use of anti-cancer drugs to destroy the cancer cells. Chemotherapy may occasionally be used after surgery if all the cancer couldn't be removed by the operation.

  • Statistics
    Gallbladder cancer causes the significant morbidity and mortality throughout the world. The incidence and the prevalence of this disease vary among the different population throughout the world. A study revealed that, in Ireland, Gallbladder cancer affects 1-5% of the entire community. Age group between 60-70 years are mostly been affected by this disease.

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