UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION

Keywords: uterine fibroids, early reproductive age, combined oral contraception, antigonadotropin releasing hormone, hormonal status

Abstract

The object of the study: Uterine fibroids (UF) in women of early reproductive age.

The problem to be solved: Improving the effectiveness of postoperative rehabilitation in women of early reproductive age with uterine fibroids based on the study of its morphological features and improvement of rehabilitation measures.

The main scientific results: It was found that in women of early reproductive age with UF the most common complaints are posthemorrhagic anemia (61.0 %, or 61 women). Regarding the menstrual cycle, the most common dysmenorrhea – 26.0 % (in 26 women). The importance of heredity in the development of such pathology in young women (32.0 %, or 32 women) was confirmed. The most common localization of fibroids is interstitial – 79.0 % (in 79 women).

Morphological study found that women of early reproductive age most often have a simple UF, namely 96 % (96 women). Uterine leiomyoma was present in 56 % (56 women).

A study of the hormonal status of women of early reproductive age found that the mean values ​​of hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, progesterone, prolactin and testosterone were higher before surgery than after. When comparing rehabilitation methods (combined oral contraceptives (COCs) or gonadotropin-releasing hormone agonists (GnRH agonists), it was found that postoperative rehabilitation by using COCs for 6-12 months provides significantly better indicators of recovery of hormonal status, indicating the effectiveness of rehabilitation method.

Scope of practical application of research results: Practical medicine specializing in the diagnosis, treatment and prevention of recurrence of uterine fibroids.

Innovative technological product: Improved algorithm of postoperative rehabilitation measures by applying COC for 6-12 months after myomectomy, which provides significantly better results in restoring hormonal status during rehabilitation.

Scope of application of innovative technological product: clinical medical practice related to the diagnosis, treatment and prevention of recurrence of uterine fibroids.

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Author Biographies

Serhii Vdovichenko, Shupyk National Medical Academy of Postgraduate Education

Department of Obstetrics, Gynecology and Perinatology

Ukrainian State Institute of Reproductology

Anna Bober, Shupyk National Medical Academy of Postgraduate Education

Department of Obstetrics, Gynecology and Perinatology

Ukrainian State Institute of Reproductology

Oleksandra Lubkovska, Shupyk National Medical Academy of Postgraduate Education

Department of Obstetrics, Gynecology and Perinatology

Ukrainian State Institute of Reproductology

Vitalii Strakhovetskyi, Kharkiv Medical Academy of Postgraduate Education

Department of Endoscopy and Surgery

References

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Published
2021-02-28
How to Cite
Vdovichenko, S., Bober, A., Lubkovska, O., & Strakhovetskyi, V. (2021). UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION. ScienceRise, (1), 55-61. https://doi.org/10.21303/2313-8416.2021.001680
Section
Innovative technologies in healthcare
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The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a <a href=\"https://creativecommons.org/licenses/by/4.0/\" target=\"_blank\" rel=\"noopener\">Creative Commons CC BY</a>, which allows others to freely distribute the published resea", "ibution 4.0 International License</a>.</p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Our journal abides by the <a href=\"https://creativecommons.org/licenses/by/4.0/\" target=\"_blank\" rel=\"noopener\">Creative Commons CC BY</a> copyright rights and permissions for open access journals.</p>\r\n<p>Authors, who are published in this journal, agree to the following conditions:</p>\r\n<p>1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a <a href=\"https://creativecommons.org/licenses/by/4.0/\" target=\"_blank\" rel=\"noopener\">Creative Commons CC BY</a>, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.</p>\r\n<p>&nbsp;2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of "], "copyright__copyright__copyright": ["", "R. (2018). Current medical treatment of uterine fibroids. Obstetrics & Gynecology Science, 61 (2), 192\u2013201. doi: http://doi.org/10.5468/ogs.2018.61.2.192\n\n\n\ud83d\udc41 188\n\u2b07 136\nPublished\n2021-02-28\nHow to Cite\nVdovichenko, S., Bober, A., Lubkovska, O., & Strakhovetskyi, V. (2021). UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION. ScienceRise, (1), 55-61. https://doi.org/10.21303/2313-8416.2021.001680\nSection\nInnovative technologies in healthcare", "R. (2018). Current medical treatment of uterine fibroids. Obstetrics & Gynecology Science, 61 (2), 192\u2013201. doi: http://doi.org/10.5468/ogs.2018.61.2.192\n\n\n\ud83d\udc41 188\n\u2b07 136\nPublished\n2021-02-28\nHow to Cite\nVdovichenko, S., Bober, A., Lubkovska, O., & Strakhovetskyi, V. (2021). UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION. ScienceRise, (1), 55-61. https://doi.org/10.21303/2313-8416.2021.001680\nSection\nInnovative technologies in healthcare", "R. (2018). Current medical treatment of uterine fibroids. Obstetrics & Gynecology Science, 61 (2), 192\u2013201. doi: http://doi.org/10.5468/ogs.2018.61.2.192\n\n\n\ud83d\udc41 188\n\u2b07 136\nPublished\n2021-02-28\nHow to Cite\nVdovichenko, S., Bober, A., Lubkovska, O., & Strakhovetskyi, V. (2021). UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION. ScienceRise, (1), 55-61. https://doi.org/10.21303/2313-8416.2021.001680\nSection\nInnovative technologies in healthcare", "R. (2018). Current medical treatment of uterine fibroids. Obstetrics & Gynecology Science, 61 (2), 192\u2013201. doi: http://doi.org/10.5468/ogs.2018.61.2.192\n\n\n\ud83d\udc41 188\n\u2b07 136\nPublished\n2021-02-28\nHow to Cite\nVdovichenko, S., Bober, A., Lubkovska, O., & Strakhovetskyi, V. (2021). UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION. ScienceRise, (1), 55-61. https://doi.org/10.21303/2313-8416.2021.001680\nSection\nInnovative technologies in healthcare", "R. (2018). Current medical treatment of uterine fibroids. Obstetrics & Gynecology Science, 61 (2), 192\u2013201. doi: http://doi.org/10.5468/ogs.2018.61.2.192\n\n\n\ud83d\udc41 188\n\u2b07 136\nPublished\n2021-02-28\nHow to Cite\nVdovichenko, S., Bober, A., Lubkovska, O., & Strakhovetskyi, V. (2021). UTERINE FIBROIDS IN EARLY REPRODUCTIVE AGE WOMEN: FEATURES OF MORPHOLOGY, HORMONAL STATUS AND REHABILITATION. ScienceRise, (1), 55-61. https://doi.org/10.21303/2313-8416.2021.001680\nSection\nInnovative technologies in healthcare"]}