 

Date of this Version

8-6-2014

Document Type

Article

Abstract

Serum and urine samples were collected from 33 NCC patients before the albendazole treatment, 3–6 and 12 months PT. At 3 months PT, 24 (72.7%) patients had no detectable CT/MRI lesions and 9 (27.2%) patients had persistent lesions. Antibody response to crude soluble extract (CSE), excretory secretory (ES), and lower molecular mass (LMM) (10–30 KDa) antigenic fraction of T. solium cysticerci was detected in serum and urine samples by ELISA. Before the treatment, out of 33 NCC children, 14 (42.4%), 22 (66.6%), and 11 (33.3%) serum samples were found positive with the use of CSE, ES, and LMM antigen, respectively. At 3–6 months PT, positivity rate was 5 (15.1%), 2 (6%), and 4 (12.1%) and at 12 months PT, positivity rate was 5 (15.1%), 0, and 3 (9%) with the use of CSE, ES, and LMM antigen, respectively. There was no significant difference in the positivity with the use of three antigens in pretreatment and PT urine samples. The study suggests that the use of ES antigen to detect antibody in serum samples may serve better purpose to evaluate the therapeutic response in patients with NCC.

Identifier

FIDC000611

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{"cc_re__cc_re__cc_by_3_0": ["nded Citation</h4>\n<p class='citation'>Venkata Subba Rao Atluri, Venkateswara Reddy Gogulamudi, Pratibha Singhi, Niranjan Khandelwal, Lakshmana Swamy Parasa, and Nancy Malla, \u201cPediatric Neurocysticercosis: Usefulness of Antibody Response in Cysticidal Treatment Follow-Up,\u201d BioMed Research International, vol. 2014, Article ID 904046, 8 pages, 2014. doi:10.1155/2014/904046</p>\n</div>\n<div class='clear'></div>\n<div id='distribution_license' class='element'>\n<h4>Creative Commons License</h4>\n<p><a href=\"http://creativecommons.org/licenses/by/3.0/\"><img alt=\"Creative Commons Attribution 3.0 License\" src=\"http://i.creativecommons.org/l/by/3.0/88x31.png\" /></a><br />This work is licensed under a <a href=\"http://creativecommons.org/licenses/by/3.0/\">Creative Commons Attribution 3.0 License</a>.</p>\n</div>\n<div class='clear'></div>\n</div>\n    </div>\n    <div id='beta_7-3'>\n<!-- FILE: /main/production/doc/data/assets/site/info_box_7_3.inc --><!-- FILE: /main/production/doc/data/assets/site/openurl.inc -->\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n<!-- FILE: /ma", "osis: Usefulness of Antibody Response in Cysticidal Treatment Follow-Up,\u201d BioMed Research International, vol. 2014, Article ID 904046, 8 pages, 2014. doi:10.1155/2014/904046</p>\n</div>\n<div class='clear'></div>\n<div id='distribution_license' class='element'>\n<h4>Creative Commons License</h4>\n<p><a href=\"http://creativecommons.org/licenses/by/3.0/\"><img alt=\"Creative Commons Attribution 3.0 License\" src=\"http://i.creativecommons.org/l/by/3.0/88x31.png\" /></a><br />This work is licensed under a <a href=\"http://creativecommons.org/licenses/by/3.0/\">Creative Commons Attribution 3.0 License</a>.</p>\n</div>\n<div class='clear'></div>\n</div>\n    </div>\n    <div id='beta_7-3'>\n<!-- FILE: /main/production/doc/data/assets/site/info_box_7_3.inc --><!-- FILE: /main/production/doc/data/assets/site/openurl.inc -->\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n<!-- FILE: /main/production/doc/data/assets/site/info_box_7_3.inc (cont) -->\n<!-- FILE: /main/production/doc/data/assets/site/ir_download_link.inc -->\n\n\n\n\n\n\n\n\n\n\t\n\t\n\t\n    \n    \n    \n\t\n\t\t\n\t\t\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\n\n<!-- FILE: "], "copyright__copyright__copyright": [" with NCC.\n\nIdentifier\n\nFIDC000611\n\nCreative Commons License\n\n\nThis work is licensed under a Creative Commons Attribution 3.0 License.\n\nShare\n\nCOinS\n\u00a0\n\nRights Statement\n\nIn Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/\nThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).\n\n\u00a0\n\u00a0", " with NCC.\n\nIdentifier\n\nFIDC000611\n\nCreative Commons License\n\n\nThis work is licensed under a Creative Commons Attribution 3.0 License.\n\nShare\n\nCOinS\n\u00a0\n\nRights Statement\n\nIn Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/\nThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).\n\n\u00a0\n\u00a0", " with NCC.\n\nIdentifier\n\nFIDC000611\n\nCreative Commons License\n\n\nThis work is licensed under a Creative Commons Attribution 3.0 License.\n\nShare\n\nCOinS\n\u00a0\n\nRights Statement\n\nIn Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/\nThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).\n\n\u00a0\n\u00a0", " with NCC.\n\nIdentifier\n\nFIDC000611\n\nCreative Commons License\n\n\nThis work is licensed under a Creative Commons Attribution 3.0 License.\n\nShare\n\nCOinS\n\u00a0\n\nRights Statement\n\nIn Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/\nThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).\n\n\u00a0\n\u00a0", " with NCC.\n\nIdentifier\n\nFIDC000611\n\nCreative Commons License\n\n\nThis work is licensed under a Creative Commons Attribution 3.0 License.\n\nShare\n\nCOinS\n\u00a0\n\nRights Statement\n\nIn Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/\nThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).\n\n\u00a0\n\u00a0", " with NCC.\n\nIdentifier\n\nFIDC000611\n\nCreative Commons License\n\n\nThis work is licensed under a Creative Commons Attribution 3.0 License.\n\nShare\n\nCOinS\n\u00a0\n\nRights Statement\n\nIn Copyright. URI: http://rightsstatements.org/vocab/InC/1.0/\nThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).\n\n\u00a0\n\u00a0"]}