Volume 3, Issue 1, March 2019, Page: 6-9
The Short-Term and Long-Term Effects of Cardiac Resynchronization Therapy in Heart Failure Patients
Xuefang Zhang, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Ying Qin, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Gaoxing Zhang, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Weidong Gao, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Yucheng Peng, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Qiang Ren, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Gang Sun, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Jinxue Liu, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Bin Zhang, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Juan Wu, Department of Cardiology, Jiangmen Central Hospital, Affiliated to Sun Yat-Sen University, Jiangmen, China
Received: Dec. 14, 2018;       Accepted: Jan. 11, 2019;       Published: Feb. 19, 2019
DOI: 10.11648/j.ccr.20190301.12      View  173      Downloads  39
Abstract
Objective to evaluate the short-term and long-term effects of cardiac resynchronization therapy in heart failure patients. Methods We continuous assessed forty-eight heart failure patients who underwent CRT implantation in our hospital from January 2008 to December 2012, evaluate/measure NYHA grade, left ventricular diastolic diameter (LVEDd), left ventricular ejection fraction (LVEF) and B-type natriuretic peptides (BNP) before cardiac resynchronization therapy and half year, one year, two years after cardiac resynchronization therapy. Results Compared to the results before cardiac resynchronization, half year, one year and two years later, NYHA grade, LVEF, LVEDd, BNP improved significantly (P <0.05); Compared to the results of half year after cardiac resynchronization therapy, one year and two years later, NYHA grade, LVEF, LVEDd, BNP also improved significantly (P<0.05); However, compared the results between one year and two years later after cardiac resynchronization therapy, there were no difference as to NYHA grade, LVEF, LVEDd and BNP (P>0.05). Conclusions CRT could improve cardiac function in patients with congestive heart failure, however, when we followed up the patients for two years, cardiac function did not improve further.
Keywords
Cardiac Resynchronization Therapy, Cardiac Function, B-Type Natriuretic Peptides
To cite this article
Xuefang Zhang, Ying Qin, Gaoxing Zhang, Weidong Gao, Yucheng Peng, Qiang Ren, Gang Sun, Jinxue Liu, Bin Zhang, Juan Wu, The Short-Term and Long-Term Effects of Cardiac Resynchronization Therapy in Heart Failure Patients, Cardiology and Cardiovascular Research. Vol. 3, No. 1, 2019, pp. 6-9. doi: 10.11648/j.ccr.20190301.12
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject", "taguida PL, Don-Wauchope AC, Oremus M, McKelvie R, Ali U, Hill SA, et al. BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review. Heart Fail Rev, 2014, 19 (4):453\u201370.\n[18]\nBakos Z, Chatterjee NC, Reitan C, Singh J P, Borgquist R. Prediction of clinical outcome in patients treated with cardiac resynchronization therapy - the role of NT-ProBNP and a combined response score. BMC Cardiovascular Disorders, 2018, 18:70.\nBrowse journals by subject"]}