"i am fused from c3 to c7 and from l1 to s1. i have nerve damage because of a botched operation. i have taken this medicine for 3 years. it is the only drug i have been able to take for this length of time and not have to titrate it up. i would take it forever but my insurance company has decided that i only need two tablets a day. i currently take 2 x 40mg er tabs 3 times a day. this was a great medicine for me and anyone on long term use should at least try it."