"i was having severe menstrual cramps, and took this.  though it did nothing for my pain, the effect it had on my mood was amazing.  i have suffered with severe mood issues most of my adult life, and none of the many antidepressants i have tried did anything to help.  within an hour of taking it, i felt normal for the first time in 15 years.  i talked to my physician, and she agreed to prescribe it off label to treat my mood disorder. i have been taking the same dose of 50 mg, three times a day for the last three years, and i am doing great."