"i started contrave last saturday may 6, 2017.  the first couple of days i felt depressed, my head felt a little weird, and i was mildly nauseous. by monday, i felt a lot better. i&#039;m still on just one pill a day.  the only issue i&#039;m having is at night when i go to bed i kinda feel like my heart is racing a little bit.  has anyone else experienced that?  so far that&#039;s my only concern.  i have had dry mouth but that&#039;s tolerable.  my starting weight was 184ish and this morning i weighed 180.4 which was encouraging."