"i was suffering extreme anxiety, weight loss and insomnia due to a diagnosed medical condition.  i tried several sleep aids and ssris.  nothing worked.  because of the weight loss i was prescribed remeron.  it was a miracle for me!  i slept through the night for the first time in months, relieved anxiety and i started gaining weight.  over time, my anxiety went away, but i stayed on because i loved having an appetite (i had no appetite for years).  i guess i stayed on too long.  after 6 years i decided i should get off.  i was dependent. i suffered flu like symptoms for weeks--nausea, exhaustion, gastrointestinal upset, feeling like low-grade fever.  i finally got rid of the nausea, but if i&#039;m off for 2 weeks, the gastrointestinal upset creeps in.  i now take 3.25mg 1x week."