"i have been on cymbalta for depression for 3 weeks now. i have had a wide range of side effects sleeplessness, stomach cramps, loss of appetite, sweating, nausea, a constant bad taste in my mouth and a total loss of libido. i spoke to my doctor about this and he said it may take a few weeks to really kick in. i hope it hurries up. i had been on other antidepressants a few years ago with no side effects. after 2 days i feel the medicine has lifted me slightly but not as much as i would have hoped."