"i started this med after 8 yrs of methadone for chronic widespread pain. was originally started out with a very low dose of 10mg 2x daily and it didn&#039;t seem to help at all. was raised to 40 mg and for some strange reason after not feeling as though it was helping and going to 3x a day i was given the name brand instead of the genetic and within 24 hrs i noticed a measurable difference. now my insurance won&#039;t pay for the name brand and although in the same dose, 40 mg 3x daily i feel like i&#039;ve been given a placebo. the name brand works wonderfully as long as i take an instant release med with it but if i don&#039;t it is not effective enough to let me sleep without tossing and turning. i am taking a total of 120 mg per day."