"i have taken bontril on and off for 5 years now.  a year on, a year off.  i would actually get up to one 105 mg a day, plus 3-35mg tabs each day.  i am 49 years old.  i have always had very good blood pressure/even a little on the low side.  my last experience with bontril has not been good.  my blood pressure has shot up to 152/104.....when i would have 110/70 readings.  i have tried to cut back on the dosage to no avail.  i will have to go off it completely.  i&#039;m disappointed, because i do think it is a great medicine to manage your weight.  i guess the moral to this story is you eventually will reach a point where your body can no longer tolerate it.  i guess weight watchers is my next step."