"just a quick note to maybe help a few folks. when i change patches i thoroughly clean the skin for the new patch and after sticking it on i press it firmly against the skin for 1 minute and the press each end of the patch for an additional 30 seconds or longer. i have not had a patch come off early in well over a year. currently use the sandoz generics at 100 mcg every 2 days.  hope this info is able to help anyone."