"i have anxiety and depression. i was really against taking medication so i tried to resolve my issues myself. needless to say, it never worked. i had been going through periods of depersonalization, feeling extremely down, suicidal and hopeless. i really thought life wasn&#039;t worth living anymore. it got so bad that i ended up in the hospital. i started taking 50 mg zoloft and honestly it has been a life changer. i don&#039;t experience depersonalization anymore. my mood has been lifted so much that i don&#039;t feel down anymore, suicidal or hopeless. if you&#039;re afraid to take medicines please just give it a try. you won&#039;t regret it. celexa didn&#039;t work for me, but i was determined to find a medicine that would. the key is to be patient."