"i was surprised to see that there were some reviews that showed it wasn&#039;t helping some people. i&#039;m very sorry for that. depression runs in my family. i&#039;ve been on over 20 different antidepressants throughout my life. nothing has ever worked. i don&#039;t recall any improvement from anything. i started fetzima about 2 years ago. i felt relief within 1 week. i couldn&#039;t believe the difference within 2 weeks. i have experienced some rough times. i&#039;ve had a few suicide attempts and woke up in icu 3 times. i&#039;m not trying to say i&#039;ve had it worse than anyone. i&#039;m just saying that was the place i was in. this was the only med that worked. the only drawback is the cost. it&#039;s very expensive without a savings card."