"i have been on depo-provera for almost four years. i have generally loved it! no periods and really no side effects. i never experience a lowered sex drive and i live life normally with the exception of no period. the only downsides are that i find myself constantly taking pregnancy tests because i&#039;m afraid i may be pregnant and not know it, and i&#039;ve gained about 60 lbs, although i can&#039;t say it was completely the shot&#039;s fault. i am now looking for another form of birth control so that i will not be kept from losing weight, just in case i gained because of the shot."