"i have suffered from severe depression for over 20 years. cymbalta the only one thing that has kept me going and feeling normal. i still have a little depression but by far i am way better less breakdown and crying and sadness. just make sure you have your doctor check your liver. i have not had any liver issues but some people have reported it. give it a try it is work for me and i know some people out there saying it&#039;s the worst but for me it has been a lifesaver"