"i started qysmia on 3/1/16 weighing in at about 217 pounds / 5&#039;3&quot;. started on the lowest trial dose.  i&#039;m making a more conscious effort to get up and move, but i can not say that i &quot;work out.&quot;  i have a sedentary job working as a triage nurse.  i did a lot of homework prior to asking my pcp to prescribe it.  i have to say that i had many concerns, but i knew that i had to try something.  he had never prescribed it before.  i talk with people everyday whose medical issues were brought on by their weight and i am scared that i am headed in this direction too.  my caloric intake is about 1600/day.  no side effects so far.  today is 3/6/16 and i&#039;ve lost 1.5 pounds.  can&#039;t tell yet if it has changed appetite yet or not.  will update again."