"i have battled depression, irritability, mood swings, crying at the drop of a hat for years. i have tried celexa and prozac and they did nothing for me.  last week i went on wellbutrin, i am taking 300 mg a day.  the only side effect i am noticing at this point is being thirsty all the time.  i can honestly say in one week&#039;s time i have really chilled out.  i used to obsess over things i could not control and now i am not as bad. i am sleeping better than i have in years despite what most people have said about wellbutrin causing sleep issues. it has also suppressed my appetite some and the urge to smoke a pack a day.  (i am down to about 5 cigarettes in a day, in 1 week).  i hope the benefits just continue to get better as my body adjusts to it."