"i am triating up to a dose of 300mg for ptsd.  i&#039;ve had no fuzziness or other issues, i&#039;m sharp as ever and i&#039;ve lost about 15 lbs so far,  i was a muscular 140 lbs at 5&#039;1&quot;, about a size 8 and now i&#039;m about 126, still losing and down to a 6.  i&#039;m about to make the step up to 200mg.  i went up in weekly steps of 25mg.  my doctor told me this was best and that there is a serious skin condition and an eye disease that can result from jumping up to a high dose too quickly, so i suggest asking your doctors about a slow triation to achieve maximum benefit and avoid fogginess."