"i have been taking propoxyphene for several years for severe arthritic pain in my shoulders.  i take it with either ibuprofen or aspirin, twice a day.  ibuprofen or aspirin don&#039;t do much to relieve the pain by themselves, but with propoxy, the results are amazing.  no bad side effects.  using propoxyphene allows me to keep up with my activities and maintain a sense of humor.  if i forget to take it, the pain comes back with a vengeance.  i&#039;m sorry it&#039;s going off the market &amp; don&#039;t know what i&#039;ll do for a substitute."