"this is my second review for orlistat. i left my first review on feb 11, 2016 just a few days after starting the pills. i was taking them three times a day. one with every meal. i had been on a super low cal/fat diet since december of 2015 and since then i have lost 52lbs in about 4 months. orlistat made me lose 10lbs the first week i was on it but after that i found it really slowed down. i decided to rely mostly on my diet and exercise more then taking the pills. my doctor still prescribes them to me and said he will continue to do so until i stop losing weight. however i now will only take them with a meal that has a higher fat content as i eat so little fat most of the time. however definitely worth trying to amp up weight loss!"