"i began sertraline 50 mg approximately four weeks ago. i wasn%u2019t sure weather to take it at night or in the morning so i experimented with both. i found that during the day i would become very lethargic and yawn constantly with little energy but would then wake up in the middle of the night stimulated regardless of the time i took it. this frustrated me as i have always had a good sleep schedule and am an active person during the day, but i had read that others had experienced similar side effects and the effects eventually ceased. i felt better for several days%u2014not as downcast, brooding, heavy. 

after three weeks of taking it, the effect seemed to even out and i found myself struggling with feelings of hopelessness and doubt again. i felt better, certainly, just still struggling%u2014i don&#039;t expect a pill to %u201ccure%u201d me of negative thoughts. i know i have control over my own thoughts, but it was that feeling of heaviness that tends to settle upon me%u2014like a dark cloud. when i went back to my doctor for the follow up, he increased it to 100 mg. i said let%u2019s try 75 mg first. he agreed. 

within a couple weeks of taking 75 mg i still yawned a lot but i wasn%u2019t having trouble with lethargy and sleep issues as much. my attitude was much better. for example, i found that i really am a funny and silly person! i forgot that i was funny being under depression. i didn%u2019t realize how serious i had become, how reclusive. i also found my creativity really opened up. i had forgotten how creative i was. i also have been going to the gym and eating well. i try and smile and interact with people more%u2014even if i don%u2019t feel like it. i may just greet people or hold the door for them but it%u2019s better than me avoiding people like i used to. some days are harder than others, but i can say that overall my experience with sertraline has been positive."