"i started on cymbalta 30 mg and it improved my mood so my prescriber increased to 60 mg.  60 mg caused increased irritability and negative thinking so i decided to taper off.  this caused flu-like symptoms and &quot;the shakes&quot; so started researching cymbalta withdrawal.  surprisingly, a lot of people have similar symptoms when coming off cymbalta.  the only way to avoid it is to open the capsules and divide the pellets to take a gradually reduced dose over several weeks.  my prescriber suggested returning to 30 mg to alleviate the withdrawal symptoms and i have stayed there for the past 2 months.  i am back to experiencing positive effects - i feel like i am coming out of a fog i didn&#039;t realize had been surrounding me for years."