"i started taking contrave for weightloss after the tremendous success of a family member. i&#039;m 56 y.o. woman 5&#039;5&quot;. 180lbs. i bike 3x/wk and eat a healthy diet. desserts are my downfall. the first week on contrave was great. no side effects, 3 lb weight loss. week 2 no noticeable weight loss. week 3 lethargy, slight nausea and headaches, dry mouth, thrust.  kept 3 pill/ a day for a couple of weeks. i decided to power through the side effects because people reported getting over them. 4 pills a day caused debilitating nausea, extreme lethargy, complete lack of appetite and migraines. cut back to 3 pill/ day, but was still sick. finally went to doc and gave up completely.  disappointed but just not for me."