"been on many ssris, a few snris, and some of the tcas. i took tofranil (imipramine) for about 6 months on a starting dose of 25 mg and eventually increased slowly to 125mg. over the course of those 6 months, my anxiety was under control for the most part, but i developed myoclonus and had to stop taking the drug. i switched to sinequan (doxepin) 25 mg, increased to 75 mg, divided into 25mg three times a day and have done well, without any side effects besides mild fatigue. no bad thoughts, lingering anxiety or panic attacks. very successful drug (doxepin) for me so far. been about 3 months now."