"well, i started taking it back in 2011 in june after getting horrible side effects from loseasonique. it caused me to breakout (even on my thighs) and i retained water like no other. so, my doctor put me on ortho tri-cyclen lo.  when i first started it, there were not any side effects for the first few weeks. after the first pack, that&#039;s when i got side effects. my face broke out. but i stuck to it. it has to get worse before it can get better right? i do occasionally have a breakout still to this day. but i have not gained weight. i haven&#039;t been sexually active while on it so i cannot say it helps keep me from getting pregnant. i was put on it for my severe cramps i get. it does make my periods lighter and no cramps!"