"was first prescribed tramadol as an addon drug with my vicoden due to a serious injury in a car accident. i also suffer from depression and acute anxiety most of my life with panic attacks. the vicoden worked at first and then made me sick. i would vomit from it sometimes then it quit working. i took the tramadol one a day usually in the morning and stopped after a month or so because i felt it wasn&#039;t doing anything. man was i wrong. my injuries healed and i stopped the vicoden. upon reading more about tramadol i discovered it acts as a serotonin and norepinephrine reuptake inhibitor. so it acts as a anti-depressant as well as a &quot;semi-opiate&quot; tramadol itself is not an opiate. you body converts it into one, similar to nucynta. great drug."