"i take 3/4 of a 5mg saphris and 200mg epilim which helps to take the edge off of my anxiety and depression. i felt a difference within days of taking my first dose, like i could breathe again and didn&#039;t have the weight of the world on my shoulders. what i will say though is that medication is never the complete answer. my medicines have allowed me to get to a stable enough place where i am able to deal with the underlying issues causing my depression and anxiety. does help me feel more comfortable in my own skin."