"i started taking zoloft october of 2011. although it has helped me tremendously with anxiety, depression, and severe mood swings. it makes me very tired and withdrawn. and i&#039;ve gained 20 lbs since october 2011! i haven&#039;t seen a lot of reviews with this type of side effect for zoloft, but i know i&#039;m not over eating to that degree.  3lbs i gained since my dr visit last week. my dr lowered the dosage by 1/2. but needless to say the weight gain is more depressing then anything."