"i have been on my antidepressants (celexa, lexapro, effexor, prozac, lithium, lamictal just to name a few) lexapro seemed to work best for me, however after a couple years its effects have reduced and i started to get angry, easily annoyed, and i always get tired around 3 or 4 pm and need a siesta so to speak. my dr put me on wellbutrin sr hcl 100mg once a day to try and combat the tiredness from the lexapro. it was filled with the generic version. i must say both my wife and i notice it has worked wonders for my anger and agitation, however i am twice as sleepy and groggy on it and have to take it before i go to sleep and when i get up i&#039;m exhausted. its doing the opposite of what almost every review i&#039;ve seen for me. im going off of it asap."