"iv&#039;e been on over 6 srris along with the combination of benzodiazepines over the past 7 years for the treatment of depression/ptsd/ocd. nothing has been so life changing and effective as clomipramine. its the most expensive prescription i&#039;ve had had ($40/mo), but its also the most helpful. i noticed the benefits within 2 weeks, with its effects continuing to increase over time. i&#039;ve been able to wean off of the benzo, and my anxiety has stayed at a manageable level. my ocd has subsided immensely, but more importantly this medication helped pull me out of a deep depression i had been stuck in for years. i couldn&#039;t be more grateful that my psychologist had the idea to try this medication, as i hear it is an older drug.try it! :)"