"i&#039;ve been on generic wellbutrin xl 300 for 12 years . i was trying to quit smoking &amp; this was recommended as it was also being marketed as zyban at the time. for me, it helped with cravings and depression and i&#039;ve never picked up another cigarette.  there are 2 things that bother me.  i cannot sleep without also taking trazodone. i just drift in and out of a light sleep otherwise. the other thing that may or may not be related to wb is that i have chronic constipation.  i say may or may not because i&#039;m scared to get off of wb to see if that&#039;s what&#039;s causing it.  different drugs work differently on different people of course but, like another person suggested, it also kept me from gaining weight until menopause. hope this helps."