"started taking bactrim about 3 weeks ago. it cleared alot of my acne in the first and second week but i started to break out in the third week. yesterday i noticed a bump on my neck just below the ear. turns out its a swollen lymphnode and its the size of a golf ball. that same day i got a severe headache and today my neck is extremely stiff so i&#039;m going to the er in the morning. bottom line is don&#039;t take it, the side effects probably aren&#039;t worth it just get a hold of accutane."