"suffered years from severe depression and anxiety.  ssris, snris naturally didn&#039;t work, and i tried every one i could!  with parnate (tranylcypromine) i&#039;ve felt normal for the first time in 15 - 20 years.  i actually enjoy the flavor of food again, the green of the grass, the freshness of a nice evening breeze, as well as my old hobbies and friends and family.  i still can&#039;t believe my luck.  also, haven&#039;t needed to change my diet at all.  fear of these drugs is overblown and usually irrational.  most psychiatrists today have no clue about them, so i would advise that you or a friend/relative self-educate before asking your psychiatrist about taking parnate or another maoi.  there are some internet sites that can help with this. don&#039;t quit!"