"i&#039;m writing this post because i spent a lot of time researching online about zoloft side effects before i finally decided to try it for my ocd/depression.  i made a mental note to let other people considering this drug know what it was like after i tried it as well.  i was worried that it might cause weight gain and that there may be sexual side effects.  i was on this medication for 2 years and did not experience weight gain or sexual side effects.  the first few months i was on it i had some stomach upset and trouble sleeping but that disappeared shortly after.  i have maintained a consistent body weight (within 5 lbs.) for years and zoloft did not seem to affect my weight at all.  i lost a few pounds at first because of the stomach upset"