"i just started taking tri sprintec after my last period, and i&#039;m now on the week of placebo pills.  i was really worried that i was going to have all the terrible side effects everyone mentions.  so far i had have had no negative side effects, aside from some spotting during the 3rd week of pills that got heavier the closer i got to the placebo pills week.  i&#039;ve had no weight gain, no nausea, no mood swings, and the best part is i don&#039;t have near the cramps i used to. my acne is a little bit better, but i read that it may take a few months for it to help my skin. i also read that the breakthrough bleeding is normal when you first start taking any form of birth control, so i&#039;m going to continue taking it and hope that it decreases with time."