"i have never written a review for anything, however i felt it imperative that i comment here on what spironolactone has done for me, with the hope that it will help others. i read the reviews here before going on spiro and all the positive comments were my incentive for trying it. i truly felt like all hope was lost. spiro has been the only thing that has worked on my extreme, disfiguring cystic acne. for 2 years, i tried everything under the sun (proactiv, 2 different antibiotics, topical ointments, gels, creams...) none of it helped and a lot of it made my skin worse. (the antibiotics made me so naseous that i was vomiting, unable to drive, even fell over.) i have had no side effects which is unheard of for me. started working after 1week"