"this helped my moderate hormonal acne so much. at first i was scared to use it because of all the reviews i read saying how it causes you to purge before it gets better. luckily for me i did not have to go through that. it worked immediately! i was taking 50 mg doxy bid with tretinoin 0.05% gel applied topically at night. my face was smooth as butter. eventually i stopped using the gel and just the doxy and it cleared my skin right up. now i get a few pimples here and there around the time of my period."