"i have had recurrent depression for over 35 years, tried loads of different antidepressants over that time. never fully recovered from last bout 2 years ago, and became sensitive to four different drugs since then. 
at last saw a consultant psychiatrist who prescribed mirtazapine on top of the 60mg duloxetine i was already on. in 2 days i feel better than i have for several years, so much energy and return of old concentration skills. i am on 15mg, then will up to 30mg in 2 weeks, and 45mg if need be. 
yes, i am very sleepy, and yes the dreams are mind blowing if the only downside is i gain weight i can live with that. i would rather have my brain back functioning as it ought to and enjoy my life. for me, this has been a miracle so far!"