"i was diagnosed with bipolar one about a year ago and originally took abilify, until i realized it gave me severe anxiety.  my doctor changed me to seroquel which i take before bed.  it did take a while to adjust to how sedating it was but it relieved me of my insomnia. however, i have been gaining weight steadily since beginning seroquel with an insatiable urge to eat about an hour after i take my medication.  no matter what i do to lose weight - 15 pounds gained since seroquel - i can not lose the weight.  i love the fact that it seems to work well with my body and cures my insomnia, but there&#039;s got to be something better for me that doesn&#039;t cause me to gain so much weight."