"i&#039;ve struggled with moderate acne since the age of 11 or 12, and i&#039;m now 26. i&#039;ve tried benzoyl peroxide solutions, salicylic acid, tretinoin cream, doxycycline oral antibiotic on numerous occasions, clindamycin cream, and the list goes on and on. nothing ever worked, and i learned to live with acne - i learned how to cover it to the best of my abilities and to try to act like it didn&#039;t bother me. but honestly at any given point i had at least 8-10 pimples. by the time i turned 24, i had started with horrific large pimples on my chin and cheeks, and i pleaded with my dermatologist to start me on something different because i had just had enough. spironolactone was the best thing to ever happen to my skin!!! i started at 50mg daily, then after 2 weeks it was increased to 100mg daily. i noticed within 4-6 weeks that my skin was clearing up and i no longer was getting new breakouts.  i&#039;ve been on it now for 10 months, and honestly i don&#039;t think i&#039;ve even had one pimple in the past 2 or 3 months. this stuff is simply amazing. if you struggle with acne, i would recommend at least trying this. i never thought i would ever have clear skin, and i now have completely clear smooth skin. it&#039;s incredible. the only side effect i&#039;ve had is fatigue, so i do take it at night before bedtime, and i wake up very well-rested. in addition, i pee a lot more often as is to be expected from a diuretic, so i drink tons of water to make up for it. also as a side note, i&#039;ve lost about 10 pounds since starting it which is also a plus :)."