"i was prescribed this cream by my dermatologist years ago and have been using it ever since. i suffer on and off from large, cyst-like pimples on my chin that haven&#039;t surfaced from the skin, and epiduo clears them before they even have a chance to surface! it&#039;s also great for the occasional pimple. i notice results in as little as 1-2 days. my only problem is makeup application; as others have said, it can dry out and flake the skin. however, a little cream goes a long way and i would strongly suggest not to lather a large amount of the product on your face."