"i have been on numerous antidepressants that seem to wear out over time.  i last had this experience with paroxetine.  my doctor suggested ritalin as an aid to make the paroxetine work better.  what a world of difference!  there&#039;s not much information out there about this, and i am sure there must be downsides.   this works for me like nothing else.  i am very careful with it, but i feel there are more upsides than otherwise."