"i started on 50mg of zoloft around 8 or 9 months ago, and it helped me a lot. recently i went and got my dosage upped to a 100mg due to a few traumatic things, i became very, very depressed. that was about three months ago and i feel a lot better, not 100% but better none the less. i never really noticed any side effects, except gritting my teeth at night, and i do think it makes me a little drowsy. as far as sexual side effects i&#039;ve had none, unlike the previous two medications i tried."