"i was initially prescribed this medication to address both a mild sleep apnea problem and persistent depression.  initially, it was indeed like a miracle drug.  i felt better immediately and continued so for about a year.  however, the drug then quickly became less effective and actually began to make my depression much worse.  i very briefly switched to nuvigil, but i continued with the worsening depression and ended up having to stop the medication.  within a few days of discontinuing the medication, i felt considerably better.  i went on to other medications to help with the depression and fatigue.  provigil/nuvigil has been a blessing for many people.  however, as with many medications, their continued use can sometimes backfire."