"i&#039;ve been on vyvanse at varying dosages (30-40 mg) for about 2 years. i&#039;ve never been on anything else really, so i can&#039;t speak to other drugs, but i feel like i got my life back. i did notice it would wear off for me around 3 in the afternoon though, and the doctor put me on a low dose of dextroamphetamine at 2:30 to supplement the rest of the day. so far, so good. i don&#039;t want to take higher and higher doses, so i try to stay where i&#039;m at and make that work. most days it does. great drug for me."