"i have been taking sertraline 50mg for the past 4 months or so. at first i utterly hated the medication. half an hour after i took my first dose, i had the worst panic attack of my life. i started to cry, i was shaking, my bpm sky rocketed, &amp; i wanted to die. i also completely lost my appetite, in the first two weeks i lost about 6-7 pounds, &amp; i am small to start. eating became a chore. i kept reading this drug was successful when you stuck with it. my appetite eventually came back, but i still needed the edge off. went to my psychiatrist, he added propanonol 10mg 2x/day &amp; i feel so good now all the time. my depression is gone it seems, my aniexty has drastically faded, &amp; my self confidence is restored. it was a rough start, but worth it."