"worked extremely well when i first started it at 20mg- i felt amazing good, started listening to music , became more affectionate and loving with friends and family , i was feeling so good that i started telling people out of the blue that i feel happy for first time in my life. but, that didn&#039;t last for very long. over the next 4-5 weeks it completely stopped working and my old depressive symptoms of my bipolar disease came back. my doc upped the dosage to 40mg to see if i could get back to the old positive state i had before at the beginning but no dice . the higher 40mg dose gave me horrible severe anxiousness, agitation , and restlessness. others have referred to this state of agitation as akathisia. i was climbing the walls!"