"i have been on minastrin for about 5 months and have had no real negative physical side effects. my boobs grew a half of a cup side but that was it for physical effects. i did, however, experience emotional and psychological side effects. i noticed that i rarely wanted to leave the house and had no desire to see friends. it made me extremely overdramatic and moody. i just switched to another bc because i was beginning to feel too depressed. i&#039;m not certain that this depression is coming from minastrin but it began around the time i started this pill."