"i been diagnosed with depression, by every doctor i been in face to face contact...i always try to hide my depression from everyone, even doctors. i would go to the er about twice a year for anxiety attack. the doctors in the er would identify my depression right away even with me trying to hide it. i taken a hand full of antidepressants zoloft, exfexar, welbutrain, and paxel. took zoloft for 2 years and gained 115lb. i got prescribe tramadol for pain, i would stand all day. immediately did not have the need for zoloft. i was able to get a better job (still standing all day ) i lost 104lb (saggy skin now). i take 50mg twice a day... on an empty stomach is best. just like everyone else tramadol has gave me my life back!"