"my doctor prescribed this to me for my depression as well as my insomnia, he started me on 50mg and ended being bumped up to 300mg. maybe i just have a strong tolerance for medication because i was also having to take 300 mg of seroquel. i stopped taking the trazodone for a while because while on both medications a bomb could go off next to me and not wake me up, but now i am just taking the trazodone due to the seroquel costing an arm a leg and a foot. but since i have done that now i get major migraines when taking it and have had to up my dose to 500mg. every now and then i will wake up with a migraine still and sometimes it makes me sick when i don&#039;t take it with a full glass and a half of milk."