"i take 25mg 5 times a day for chronic pain caused by degenerative joint disease in my knees, hips, ankles, and lower back. i feel i got slightly better relief from oxycontin but i really didn&#039;t like the loopy feeling and the extreme cravings i had, my sister who works in a vets hospital pharmacy said i should try methadone and that was the smartest thing i have ever done. methadone controls my pain very well and then i have endocet  10/325 for breakthrough pain as needed. the best thing is no cravings. i won&#039;t say that there are no withdrawal feelings when i don&#039;t have my methadone for a couple of days but nowhere near what i had with the oxycontin. overall i will say that methadone is a wonderful pain medicine and anyone with chronic pain should give it a go."