"i rated this medication once before, i felt a need to update my review. i&#039;ve taken saphris since &#039;13 @ 30 mg. nightly and over the past 5 months i&#039;ve slowly tapered down to 10 mg. with high hopes of discontinuing. saphris got me out of a bad spot, i remember being horrified of answering the door let alone leaving the house i was so delusional. i got out of that spot, slowly got on my feet and some what rejoined society. my positive manic spirit is gone, i&#039;m always tired &amp; feel like life goes on around me, not with me. its very hard to discontinue, i have panic attacks daily now and am beyond stressed. i feel like i&#039;m trapped, no worse--or better--on or off after all these years."