"was put on this by my pd for around the clock pain relief. at first it seemed to work fine with minimal sides. the er that i was on definitely didn&#039;t last anywhere close to what the company claims in their literature. could feel it wearing off after just 3 hrs. sides were minimal but the hot feeling that some have mentioned here started becoming very annoying, and that was only with the 100&#039;s. mentioned this to my pd and all she did was put me on a higher dose - something tells me she must be getting huge kickbacks from janssen, the mfr."