"this medication has worked very well for helping to control my break through pain of rsd/crps which is the most painful chronic pain disease there is.  i have been on 10/650 for a long time but now my doctor is concerned that i am getting too much tylenol in my dosage - i am going to try to get her to move me to 10/325.  the max dosage of tylenol should be 2650 mg a day, not 4000 as it has been updated.  i am not worried about becoming addicted as i take my dosages as directed.  there is a huge difference between addiction and dependence of your pain medications.  i also take opana er 40mg 2 x day.  these two medicines work well for me."