"i am a 57 year old male and struggled with anxiety and depression all my life but it peaked about 6 years ago.  i began taking the maximum dosage of wellbutrin 450mg.  i was better, but not 100%. i would still get that &quot;knot in my stomach&quot; when the anxiety would rise.  i asked my psychiatrist if i could try pristiq since my mother had good results.  he reduced the wellbutrin and put me on 50mg of pristiq.  i started feeling better after about the 3rd week and after a month, those negative thoughts, not being able to live in the present, lack of joy all changed dramatically for the better.  to me, it is a wonder pill - with no side effects at all.
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