"i was off meds for awhile and thought i was fine - nope!  had a manic episode.  i take 100 to 150mg of seroquel at night.  before this, i took geodon and lost weight, but i had uncontrollable muscle movements, i didn&#039;t want to switch but my family was embarrassed by my non stop hand movements.  i switched to seroquel and feel a million times better.  i sleep great (used to not sleep for days).  but, i have gained 40 lbs.  i wake up the next morning and see what i ate the night before and get so irritated with myself.  it makes me want to eat everything bad for me.  if i don&#039;t eat, it&#039;s like an itch i can&#039;t scratch. i don&#039;t feel foggy, but well rested...then again, i sleep till 8 or 9am. to me, it&#039;s worth the weight gain to feel stable."