"i have bipolar disorder i, with rapid cycling and mixed states. i tried saphris when i was recovering from a hospitalization which was very unpleasant and ended very badly. so i was a bit manic and terribly anxious going on it. i took it for 6 days. it seemed to work almost right away. i was shakey and anxious throughout the 6 days. extremely sleepy and dizzy after my 5mg at bedtime. but that wore off after 4 days. mood-wise, it seemed to completely stall my cycling. miracle! and i was much calmer and less reactive, but definitely awake during the days. then after my 6th dose i noticed my lips were puffy, and my tongue was fatter, then my throat got tight = allergic reaction. worked great until that!"