"my doctor wanted to try me on nucynta for my sciatica pain since ibuprofen and ultram did not work very well.  i tried one dose friday night 75mg, and woke up saturday morning with a horrible headache.  then an hour or so upon getting out of bed, it turned into the worst headache of my life and then had nausea and vomiting with it.  i wound up having to go to urgent care and they gave me a shot of toradol for the headache and a shot of phenergan for the nausea and vomiting.  i finally felt better after awhile.  these side effects were too horrible for me."