"it took a month at 60mg a day to notice a big change. after two months of treatment with parnate i am feeling wonderful! i&#039;m able to go out in public without panic, i&#039;m more social, i&#039;m dating again, and my energy level is up. i&#039;ve lost over 30 pounds in the first 7 weeks of treatment- which is great for me since other meds i have been on made me gain a lot of weight.  this medication is wonderful, but takes time to fully kick in."