"i have had acne since i was 13.now at 18 i have been using epiduo for five weeks now. like most of the people on here i too experienced extreme burning. i actually even got a rash by my lip area. i also had puffiness around my eyes. i almost gave up on it, but my dermatologist told me to slow down the use of it and reminded me to only use half a pea-sized amount. my skin is completely clear. i do have blemishes. they are slowly fading away. i am using my eczema medication (pandel) for the rash. she informed me it should be gone in about 5-7 days(hopefully). i am currently using hydroquinone 4% for the blemishes. i just started 3 days ago and i am already noticing an improvement. i highly recommend epiduo. way more advantages than disadvantages"