"i am a female, 44 yo, took pristiq over 9 months up to 100mg. it gave a little relief to my depression but did nothing for anxiety and panic attacks. i left my job on disability while on it, unable to cope anymore!  i am still trying to find the right antidepressant.  tried zoloft, manerix, celexa,cymbalta, wellbutrin without noticeable success or just bad side effects!  note i had no major side effects with pristiq."