"i have been taking wellbutrin 300 mg for about three years. i was taking zoloft for anxiety before that and absolutely hated it. the first couple years on wellbutrin was great. i wasn&#039;t having anxiety attacks and stress was normal. however, i think my body got too used to it and now the effects are minimal. i can feel some difference, but my anxiety has been an all time high this past year. since there&#039;s nothing higher than 300 mg, i&#039;m planning to try something different. i did like wellbutrin, no side effects. just doesn&#039;t work well for me anymore."