"ok i&#039;m 51 yrs female. suffered along thru life with anxiety. when younger it was manageable.  until the last 5 years after loss and my fair share of medical issues leaving me overcome with severe anxiety and depression. fast forward today my physian petscribed effexor 25mg. in the past 5 years have tried others with side effects. i&#039;m only on day  5  and feeling so tired and have mild diareeha and some little anxious feeling. the tiredness is profound. will update in a week."