"i started taking phentermine just a little over a month ago weighing in at 307. my doctor started me out with half a 37.5 mg pill 2x a day. i immediately felt the medicine start working, the jittery jumping out of your skin feeling and i had a lot of energy the first few days. i sweated profusely and had to have water by my side at all times.  i felt the meds even out and by the 5th day i was asking my doctor to let me take a whole pill once a day. i make sure i take my dose early when i first wake up. so in about 5 weeks i have dropped down to 293. this drug is life changing for me. i should be on disability and i&#039;m in chronic pain but this medicine has seemed to help me beyond the appetite suppressant. i&#039;m a 40 year old female with hope!"