"just started pristiq yesterday. i&#039;m taking it to replace cymbalta which i gained 10-15 lbs on in two months. 60 mg of cymbalta was awesome for my anxiety but the weight gain was antagonizing my depression. i also take 200 mg of wellbutrin sr and have taken that for a long time. 
i&#039;ve been a little jittery since starting the pristiq and spent some time in the bathroom last night. i&#039;m coming off cymbalta slowly over the next week so right now it&#039;s hard to judge how the pristiq will work. i take xanax as needed and took some today as i was feeling tense. i attribute this to the adjustments i&#039;m making. glad i picked labor day weekend to make the switch. i&#039;ll keep you posted on how it goes."