"24 hr medicine for pain, i only got 6 hours of minimal relief.  started on the 20 mg for 1 month, then dr switched me to 40 mg for 1 months, then 30 mg for 1 month.  it always seemed to start working long after i took it, about 12 hrs and made me extremely sleepy and tired, along with pain.  in the 3 months i took it, i gained 15 pounds without even eating more or differently because i was constantly nauseous with it.  who wants food when queasy?  i have been prescribed and instant release pain med and have been on 2 days.  it works great with no side effects and i have lost the 7 lbs of the 15 the hysinglia  made me gain.  hopefully the other 8 lbs will come off quickly too because the weight gain from the drug caused my a1c to go"