"i have been taking spiro for about a month now and so far so good. i am noticing a bit of a break out right now but nothing crazy like my normal acne. the only side affects i am noticing is the muscle weakness and light headedness... i dropped a cookie sheet of calzones, using both hands. i literally couldn&#039;t pick it up. the muscle weakness comes and goes though so i can deal! same with the lightheadedness. :) i am so happy! i have gone from having really bad cystic acne, to little tiny red bumps. i can deal with this, i am starting to feel beautiful again! i am only on 50mg at the moment, so we&#039;ll see how the next few months go."