"when i first went on this medication 300mg i did not like it at all. i had side effects of a type of floating- my head wasn&#039;t attached to my body- i&#039;d be disorientated, only for a short time, but frequently at first. i don&#039;t really remember any other side effect.  i wanted to stop taking this. i was 300 sr then went to normal seroquel.  being on standard seroquel helped.  i asked to change off seroquel and was told its a good medicine and just give it time- 6 weeks. wow, i didn&#039;t like that idea.  i did give it time,  i was tried of a day, so went back to 150mg- over time i&#039;ve been on 200mg also and now 300mg.  i am so grateful to myself for hanging in there.  i choose to be on seroquel,  i sleep a deep sleep, for me, i am happy. very happy."