"been on 150mg of venlafaxine for 12 years upped a year ago to 225mg and havent noticed a difference.
my daughter knows when i haven&#039;t taken it though....i either go manic or very low. i still have more lows than highs.
i am 51 years old now and was first put on valium at 2.5 years old.
i was told years ago it was clinical depression with manic tendencies...my eldest brother had the same (other 2 brothers...no mental illness) as me....he committed suicide a number of years ago."