"was on ortho tri-cyclen lo 4 yrs ago for 2 years, kept a healthy diet and exercised. gained a little weight, but just on my girly parts! very mild pms, reg and moderate periods. had a baby last year and used the mini pill for 9 months. only been on tri sprintec for 6 weeks and right away i noticed side effects. it wasn&#039;t until i read some reviews that i realized i was getting hives from it. i have pretty bad allergies so i thought that was why. i am a very optimistic person and anytime i feel in a bad mood i do any/ everything to come out of it. it seemed like i was constantly trying to pull myself out of a funk. also, noticed a decrease in appetite and libido. the positive is clearer skin- except for one recent breakout, it&#039;s free and i&#039;m not pregnant."