"i was prescribed seroquel after i got out of one of those psychiatric hospitals and after a terrible bout with abilify (extremely jittery and restless). unfortunately, seroquel affected me in just the opposite way. i consistently went up in dose, peaking at 600 mg for 2 days, then dropping back down to 300 mg. i was on it for almost a month but i was living in my own little world. i was very muted. it may have stopped the manic episodes, but the depression became worse, almost landing me back in a hospital after i went &quot;cold turkey.&quot; the good thing though was that i slept so peacefully every night. no racing thoughts."