"so i am 19 years old it is august (a month after my birthday) so i have been on depo for there years exactly. my first couple weeks i had nausea and headaches. after my third shot i had no menstrual cycle anymore. i will say for this form of birth control is awesome. i was with a guy for a long time and never used a condom and here i am three years later and never had a pregnancy scare. so yes as birth control it works perfectly. however, throughout the years i still had some mild cramps and horrid mood swings and my right knee seemed to gradually get worse. pains that came and went more when it rained. i am now in the middle of getting depo provera out of my system and i must say i feel like i am dying. horrible mood swings nausea headache"