"i have only been on lamotrigine for three weeks now but it is starting to work for me already. i started at 25 mg for the first two weeks, then increased to 50mg last week, as directed by my np. i was misdiagnosed for 13 years with major depression before this. i tried several different antidepressants that did not work in the long run. when i was rediagnosed by my np and a clinician at the local mental health institute, i went on an anti-seizure med that also treats bipolar (can&#039;t remember which one) but it made me sleep for over 12 hours each night and i was extremely groggy the day day. so i was put on lamotrigine. so far, the only side effects i have are increased hunger and worsened insomnia (already have insomnia no matter what."