"i have been on lo loestrin for about 2 years. when i first started, i had pregnancy symptoms for about the first week: sore breasts, nausea, etc. - however that subsided. i no longer have my period which my gynecologist informed me is very common. every now and then i&#039;ll have a month where i get cramps during the &quot;reminder pill&quot; portion of the pack but it&#039;s not common. i take my pill every day at the same time (before bed - set an alarm!) and always keep an extra pack in my purse in case. no weight gain, no acne. i&#039;m very happy."