"i used to only get a pimple here and there on my cheeks. when i started tri-sprintec my acne got significantly worse. i was getting deep cystic zits all over my cheeks. after 3 months or so my acne calmed down but it was still worse than before. a year later and my acne is still worse than when i started the medication but i&#039;m terrified to go off of it because i&#039;m scared of the breakout that will happen when i go off of it. wish i never started taking it, it&#039;s ruining my life."