"i have been taking latuda for about 6 months for bipolar disorder. i was taking just seroquel but had breakthrough anxiety and depression, so my psychiatrist added latuda. it definitely has helped with my depression and anxiety. my big issue is i can only tolerate 10mg/day. anything more than that and i have severe insomnia. also, having to take it with 350 calories is a pain. i take it at lunch time. 10mg dose does not make me sleepy. i would warn anybody taking this medication to be careful when stopping it. i abruptly stopped it a few weeks ago and sunk into the worst, deepest, most god awful depression of my life. after a week, i started back on the latuda and 6 days back on it, i&#039;m feeling better."