"my doctor switched me from loestrin fe to microgestin fe to help my endometriosis. i could not figure out why i have been so miserable (tender breasts, extreme cramping and bloating, weight gain, and depression) but after reading some of these reviews i can relate. the best oral contraceptive that i have tried is loestrin 24 but my insurance doesn&#039;t cover it! the only positive thing from this experience: i&#039;ve given up on it and my husband and i are trying for a baby!"