"i have been taking 300mg of lamotrigine each day for about 3 years.  when i first took it, it made me feel sick and anxious and gave me headaches, but after following some simple advice from my psychiatrist i now dont get any side effects at all!!  he told me to increase the dose slowly (25mg per week) and to always eat when i take the tablets.  i&#039;ve found this medication very effective as an antidepressant but not effective at controlling mania / hypomania.  despite this, i still rate it very highly because it is so much more bearable than any other psychiatric medication that i&#039;ve taken in the past."