"i&#039;ve been under pain management since 2007 and was on 30 mg of morphine sulfate er 3 x per day supplemented with 15mg of percocet 4 x a day. after a couple of years of this regime i changed my pain management doctor and he suggested going to exalgo. i began taking 2 x 12 mg exalgo every mornings. it took about a week or 10 days to begin acting. exalgo is better than the morphine but, the 60 pills i need each month, after my insurance pays, is really expensive."