"i have extreme anxiety and major depression. for me, all ssri&#039;s, ssnri&#039;s make me feel extremely weird. almost as if my body feels &quot;too good&quot; but not in a good way. the only way to describe it is like jolts of electric shocks throughout my body that feel good. also when i yawn or take a deep breath my teeth start to chatter. it also creates extreme erectile dysfunction for me to the point where it burns when i urinate. unfortunately these are symptoms i cannot put up with, even though it does work."