"after being in denial, i completely broke down with anxiety and depression. went to my doctor and prescribed me pristiq. after a week i took a big turnaround for the best, so happy! stick with it, give it a chance to work. side effects were nausea for the first few days stomach upset, but don&#039;t give up! i have been on celexa in the past but takes to long to kick in..plus 40lbs weight gain. pristiq cuts the appetite ,and you not hungry, at least if you needs a few lbs off this is the medicine to be on!"