"i have bipolar1, general &amp; social anxiety, post traumatic stress disorder and borderline personality disorder. i&#039;ve been on pretty much everything over the last 14 years. seroquel worked well for over a year but the weight gain was awful. regular exercise and healthy eating. lithium and lamictal replaced the seroquel and seemed efficient, couldn&#039;t handle the nausea anymore after 2 yrs. 5 weeks ago i decided i wanted try saphris. psych agreed, decided to start low and slow as i tend to have allergic or increased anxiety with most medicines. started on 2.5mg for a week. i literally felt better the next morning. i had increased energy and felt happy for the first time in over 10yrs. i&#039;m up to 5mg pm, 2.5mg am. anxiety decreased, and down to 1.5mg of klonopin daily from 3mg. this is a miracle for me! "