"i&#039;ve been trying different combinations of medicines for a good 6 years. i was put on trintellex about a year ago, and that helped some, but my depression was still disabling. recently, i went to my psychiatrist and asked for a change in medication. she decided to add rexulti as an add-on to my trintellex. the result has been phenomenal. i feel better than i have in years. i have more energy, i&#039;m less anxious, and i&#039;ve been able to leave my house without feeling overhelmed at all. this medicine has is working very well for me."