"i am 65 and have ptsd from the loss of my son. i was prescribed xanax and klonipin for a few yrs but they did not deal with the panic attacks that i was experiencing. i cannot take ssris due to side effects, so i mentioned the seroquel to my doctor who said it did have a mild anti depressant effect. i take .25 mg in the morning, and 3 of them at  night . no weight gain, i am very active. if anything, my appetite has fallen. i sleep 8 hrs rem sleep and don&#039;t really need as much of the xanax or klonipin now. the seroquel has helped me function greatly and won&#039;t allow the panic to set in. so, i am happy with it."