"i was on sprintec for 4 years. for the first 2 years i had no problems, but then i got sick and i think my body changed after that. i became irritable/depressed, no libido at all, and my face began to break out when i&#039;ve never had skin problems. i am starting to believe that the pill is making me feel this way. as far as preventing pregnancy it&#039;s great, i&#039;ve missed a day or 2 and have never had any problems. i am switching and hoping that helps"