"i have been on contrave since tuesday, 9/1/15 and i&#039;ve lost 2.6 pounds so far - not bad for only taking it for 4 days. i will say that i did experience very mild nausea the first day, but had some cheerios as someone else mentioned and it helped. i also have had diarrhea/loose stools every day - my boyfriend says that&#039;s why i&#039;m losing, which is probably true. i am not too concerned about it because i had been told years ago that i have irritable bowel and i do occasionally have this issue. my starting weight was 236.6 and today i weighed in at 234.0. i will report more in the coming weeks."