"epiduo is fantastic. i&#039;ve only used it for 3 weeks but my skin is so much clearer (i had moderate acne). however it is a prescription treatment and you have to be careful with it: use it sparingly and just once a day, more won&#039;t work faster. the best way to do this is to buy a gentle cleanser and moisturiser (cetaphil and eucerin are fantastic as they&#039;re formulated for skin undergoing acne treatment). cleanse and moisturise morning and evening, and follow with a very thin layer of epiduo every evening. the dryness and flaking disappears after 10-14 days, so be patient. if your skin is sensitive, the best thing to do is to apply epiduo after your moisturiser has sunk in. this creates a barrier but the treatment works just as effectively."