"as a septic and someone who hasn&#039;t had good experiences with antidepressants i must say this medication has been amazing. i must have tried 6-8 different types and always felt they either didn&#039;t work or the side effects were too unbearable. i went to my gp to go back on to lexapro as it was the one i did best on (but lost all libido) and he suggested pristiq which is similar but not supposed to come with the same side effects. so far (8 weeks in) i&#039;m pleased to say it has been a blessing. as had a major impact on the my depression which was getting disturbing and i am feeling no immediate side effects."