"i was put on 45mg of this drug a couple of weeks ago and all is going well. i was given norco 10/325 to help with the breakthrough pain. the morphine combined with norco are hard for me to take together. i am taking 15mg every 8 hours, and it seems to be doing the job.  there are times i feel fine when the 8 hours is up but it says not to miss a dose."