"marplan did an amazing job of keeping my depression away from 2010 through 2017.  i&#039;d tried nardil &amp; parnate prior but had weight gain/hypomania w/ nardil and ridiculously high blood pressure after each dose of parnate.  marplan is sometimes said to be nardil&#039;s weak little sister (as it&#039;s also derived from hydrazine unlike parnate which is derived from amphetimine).  it worked great for me.  no weight gain, was able to perform sexually, and it kept me in a good place.  marplan always felt very clean, i never had a hypertensive issue, but it did the trick.  the cost though (looking at you validus) is robbery.  current insurance $160/month - jan 1st insurance won&#039;t cover so $1500 a month.  nope."