"i started on 0.6 of saxenda on aug. 10th. i administer the shot in my inner thigh at 9:30pm every night.  the needle has only hurt once and only once did i have a bruise for a day. for the first week, i didn&#039;t experience any negative side effects. i did start to feel a slight decrease in appetite, though. a week later i doubled the dose to 1.2.  that night, i had severe abdominal pain and had to use the bathroom three times that night.  for 2-3 days i had an awful taste in my mouth, but that has gone away.   i&#039;ve seen a huge difference in my appetite.  i am a 47 year old female that weighs 184lbs.  i haven&#039;t gotten on the scale because i am afraid i&#039;ll be disappointed but i do feel &quot;lighter&quot;. i am eating much less and don&#039;t crave most foods"