"at 24 i started breaking out worse after discontinuing the pill and switching to an iud (i love it, btw). i had cystic acne along my jawline and on my neck, so i went to a derm and she prescribed me 25 mg daily for 2 weeks, then 50 mg daily. i broke out badly at the 2 week mark and again at the 4 week mark. i went back to the derm after 6 weeks of being on spiro and i was upped to 100 mg daily. i&#039;m finally starting to see results. i&#039;m on week 8 of being on spiro, and while my skin isn&#039;t completely clear, i definitely see a difference. i should also note i&#039;m using retin-a topically. i do experience side effects on spiro like increased thirst, breast tenderness, spotting, some cramping, &amp; increased urination, but i&#039;m willing to deal with this"