"i&#039;ve been on cryselle for about 6 years, never had a problem. no side effects never experienced a headache (but i never get headaches prior) periods always come on the 3rd placebo pill day and last 2 days and the 3rd day is spotting. no crazy hormones and no acne at all. the first pack u will experience nausea as any birth control pill because the hormones but should subside by the second pack. i did stop taking the pills after about 5 1/2 years when i noticed my vaginal mucus started smelling funky for about 2 months, when i stopped birth controll completely it went away and then i had a baby, just finished my first pack of cryselle post pregnancy and the same smell is back. maybe i was on it for too long though! hope this helps"