"i have taken asenapine for about 3 weeks now. before i took olanzapine depot injections but i gained about 100 pounds. too bad cause it had good effect on me. the first days on asenapine i did not notice much. but the last two weeks i have been more unstable then without meds. my mood swings are extreme several times a day! i become really angry and scared at the same time and i get panic attacks from hell. it got so bad i was admitted to acute psychiatric ward 5 days ago. i have to take large amounts of valium to help with the panic attacks. tomorrow my doctor comes for a meeting and they will probably take away the asenapine. at least i hope so. i also take fluoxetine and wellbutrin but i don&#039;t think there are interactions"