"my doctor recently prescribed pristiq for me when i went to see him for help with my mood swings. after a rather nasty incident at a family dinner, i decided that i needed help. my family has put up with these swings for years, and sometimes i cry when alone.  i did not realize that i was suffering long term depression.  i am only on day four of taking this medication, and already i can feel a difference. i don&#039;t feel as moody or down in the dumps.  i hope this effect continues, as my past self was breaking my family up. i do agree with other posts here that it decreases your appetite.  i do not feel like eating at all.  as for sleeping goes, i have always had a problem in this area due to being a shift worker. i take sleeping tablets."