"have been on this medication for 4 yrs for anxiety disorder &amp; fibromyalgia. cymbalta has definitely helped with both conditions. without it, i&#039;d be in an almost constant state of anxiety &amp; the fibromyalgia flare-ups would be much worse. (found this out when i reduced the dose from 60 mgs a day to 30mgs every other day, after hitting the expensive medicare &quot;donut hole&quot; last year. that reduction also caused severe depression within a month and i&#039;ve never been diagnosed with depression!). my side effects include some gastrointestinal problems &amp; 30 lb. weight gain, despite daily exercise/diet. (all ssri&#039;s cause weight gain for me). hate the extra weight gain, but it&#039;s better than having anxiety/fibromyalgia pain."