"at the age of 24, i unfortunately developed severe acne on my lower face. tried everything the dermo suggested, antibiotics.. some prescribed creams...then epiduo. doctor told me i&#039;d have some irritation/dryness/redness and my acne might get worse before it got better for a few weeks... so for 12 weeks i patiently followed the doctors directions using the suggested cleanser/ moisturizer for the dryness and my nightly pea size application of epiduo. this product..*sigh*  made my acne worse.. for 12 weeks!!! more painful deep zits, bigger pores, more outbreaks... like i didn&#039;t even go out anymore it was so bad. i quit using it from frustration and oddly my acne cleared up 90%. maybe i had a reaction? who knows."