"i was very reluctant when my doctor suggested seroquel for my condition. i had been on it before as a sleep aid and while it did improve my sleep greatly, i was miserable the next day. this time he wanted me on it round the clock, and it has made a huge difference. it would seem strange that something which makes you drowsy would help depression too, but for me, this seems to have been the case. i&#039;ve had very little depression since we got up to the full dose. i&#039;m now on seroquel xr 200mg."