"i&#039;ve taken effexor for 7 years, in a dosage that has decreased from 225mg to 75 mg over the last 2 years.  while i had some benefit with depression i experienced side effects from effexor. i experienced short term memory loss, problems concentrating, blurry vision, weight gain, sweating, and dry mouth.  i cannot drink at all on the medication, since it exacerbates the memory and mental focus problems enormously, even at one glass of wine."