"i take 10 mg/day. before i started taking this i felt as though i had severe pms everyday. i suffer from moderate to severe depression, anxiety, mood swings, anger problems, and ocd. my therapist has diagnosed me with ptsd. anyway, the first week of taking this i had a lot of side-effects. i took it in the evening, and had insomnia. waking up a lot at night. initially, the first week, i also had decreased appetite and chest pain that would come and go. after the first week i began taking it in the morning. the insomnia and all other symptoms subsided, but then i became extremely tired during the day. i&#039;m now taking it in the evening again. helps a lot. no more depression or irritability. only problem now is increased appetite."