"all i can say is don&#039;t give up - the dosage might not be right! i was on this for 2 months at 100mgs for 2 months  without any visible difference.  the doctor suggested i double the dose which i resisted doing, but when i did i felt better almost immediately and have been fine for 8 months now despite a challenging few months. the dosage makes all the difference. some people are better on low doses, other, like me, do better on a high dose."