"ive been on depo on about three months, and im just about to get my second shot. my arm really ached for a couple days after the shot, but eventually that went away. the first month was really rough, i had a continuous period for the whole month, i had major mood swings, major cramping. it was hell, and if you would have asked me, i would have told you that i would not get another shot. the second month wasnt too bad, although i had quite a bit of spotting and this month has been better. it&#039;s getting better and im feeling positvely about getting my second shot."