"5 plus years of lumbar/neck/shoulder/ankle/fibromyalgia/arthritis, etc, etc. for me this medicine is superior to anything i have tried, and tried them all. been on 100mg 3 time a day for the last 1 year and a 1/2. they only thing this has not helped for me is migraines. i have noticed the side effects are less when taken regularly 3 times a day."