"if i could rate this drug a negative 10, i would.  it has an array of negative side effects, and should not be taken long term.  i lost about 10 lbs in three months, but my body developed a tolerance and i only maintained the 10 lb weight loss for the next 3 mos. while on it,  i did not feel it had any extremely worrisome side effects, but once i went off of the meds, i realized how anxious, moody and exhausted i had been.  this is speed.  you get a rush for 6-8 hours or so, but afterward, there is a crash.  this crash prohibited me from any effective exercise. after i went off, i gained 25 lbs in approx 3 months and am now 16 lbs heavier than i was to start.  my physician also prescribed this med to two of my friends who are not obese."