"i&#039;ve tried many different ssri&#039;s for depression (zoloft, wellbutrin, prozac) and nothing worked.  i was apprehensive to take the effexor because of online reviews but i&#039;m so glad i did!  the only side effect i&#039;ve had is tiredness the first few weeks but that has since subsided.  i not only feel more energy but i actually can feel happiness.  on the other medicines i just felt a numbness and lack of emotion but effexor has made me feel like me again!  this has been my miracle after years of mild-severe depression."