"i started in march 2017 @ 195 lbs.  side effects were rough for the first 4 months... nausea, vomiting, severe stomach pain right after eating. so. i kept pepto in my purse to keep me going. it is sept 14,2017 and i have zero side effects, i&#039;ve lost 40 lbs. i went from a size 16 to an 8. i have 20 lbs to go! i plan to stay on this as a maintenance drug. i absolutely love it and pushing through the side effects was worth it."