"i have been suffering with severe anxiety and depression after developing panic attacks. i have always suffered with generalized anxiety but have not had panic attacks for over 12 years. i haven&#039;t taken any medication during that time. i was driving home one evening and out of nowhere a severe panic attack hit me and left me immobilized on a bridge where i just froze. fatigue, anxiousness, guilt and dread. while i am receiving help from a counselor and my gp, i have been taking zoloft 100mg in the morning and 50mg of seroquel. seroquel has helped me considerably. i take seroquel at 6pm which usually helps me fall asleep by 9.30pm and wake around 7am. this reduces the hangover effect. i am feeling better since taking seroquel."