"i have started taking seroquel three weeks ago. i&#039;ve been prescribed 25mg twice a day. i was not able to sleep staying up one day, one night, one day and maybe going to sleep that night or the next. i&#039;ve been told i have anxiety. that dose wasn&#039;t working for my sleep so i started taking 50mg at night as well as the 25mg twice daily. it has worked for my sleep. the only thing is i take the two tablets at night and i don&#039;t feel like going to sleep but i switch off sitting down watching t.v. it&#039;s like i can&#039;t get myself to bed. i wake up a couple of hours later then go to bed and fall to sleep, no serious side effects, no weight gain so far."