"i was on brintellix for a short time while trying to transition from lexapro. unfortunately it was just not the drug for me. i had terrible nausea that never went away, as well as vomiting. brintellix didn&#039;t really do anything for my anxiety, either, and i definitely noticed symptoms of that again. by the time i stopped taking it, my depression was actually worse, but i think it didn&#039;t help that i was feeling so bad physically. if you already have digestive issues, this might not be the med for you."