"i was prescribed seroquel xr for bipolar depression my dr started me on 50mg and i am gradually increasing the dosage its been about 4 weeks and i am currently taking 200 mg i will agree that it has helped the hopelesness feelings  and suicidal thoughts  which is a plus but the zombie like feeling and dry mouth are tough  i have a job that requires constant activity its hard to keep up have to definitely slow down  my dr advised me that these side affects are all normal and eventually i will get used to it can&#039;t wait for this to happen"