"i had tried numerous anti depressants before settling on citalopram. it had the least unpleasant side effects for me. i have taken a small dose daily for approx 5 years. it seems to help me to not feel so low. i&#039;m not sure if some of it is possibly psychosomatic eg a placebo affect. but i&#039;ll keep using it as long as it seems to help. my type of depression has been long term since 18. i&#039;m now 53."