"i have been on zoloft and celexa, both just taking the edge off, for the last 7 yrs. i had been in a pretty deep depression for the last few months, so my pcp suggested viibryd. she told me to take it in the morning with food for the nausea. i took the 10mg dose with half my daily celexa dose for the first week. i felt a difference on day 1. the clutter cleared up, unreasonable emotions were easier to control, i actually felt happy. i have experienced mild gastrointestinal issues, evening sweets cravings and stomach bloat, none of which i realized were side effects until reading up here. i am now on my second week of 40mg/day doses, feeling great. i combat the restless leg (read: whole body) by dosing in the morning with food. i have very high hopes for this medicine."