"so i&#039;ve suffered with acne basically since i hit puberty (now going on 21 years old). i&#039;ve tried every type of med, cream, etc. i was given epiduo with just a fair warning of dryness which i assumed anyway.. after starting this medicine i began having dry, painful, red, burning skin. i read reviews to make sure this was normal and it seemed to be. here is my advice... stick it out. &quot;it has to get worse before it gets better&quot;. i have finally found a great skin care regime to go along with this medication and it&#039;s amazing. my face has cleared up so much (still not 100% but mostly because of stress) as a result of this medication! the pain and dryness was totally worth it!"