"have suffered with clinical depression for fifteen years and have been on numerous antidepressants. have now been taking lithium for 9 months and have had a lot of problems including hands shaking, legs feeling as though they are going to give way a lot of the time, whole body feeling heavy, nausea, parts of my body suddenly jerking, sweating, but worst of all i feel as though i have had a personality transplant and do not recognize the agitated person i have become, the nightmares, my partner is very concerned.  i am reducing the dose to come off it. i have just noticed on this site that it has a high interaction risk if taken with venlafaxine which i have been prescribed with it at the same time."