"have taken other medications in the past and stopped due to the side effects.  now i take bupropion xl 300 mg a day with no apparent side effects.  i can laugh.  i can still cry.  i don&#039;t dwell on bad things.  it makes me just feel better.  but dr accidently wrote for sr once.  i went ahead and took a dose (thinking it would be basically the same, only a little faster acting - i took a 150 mg dose) and was sick as a dog and felt drugged.  amazing the difference in xl and sr - and i imagine the fast acting would be even more severe.  i&#039;ll stick to the xl."