"i have spinal stenosis, ddd, bone spurs, ruptured discs, double laminectomy at l5-s1, l3-l4 in 2013. i&#039;ve been on oxycodone for over 4 years. that worked great but i started at 100 mg a day and even now only at 80 mg a day, so i think it is not out of the ordinary to have a built up of tolerance. dr. switched from four 20 mg oxycodone to four 10 mg oxymorphone. he said it is equivalent to 25 mg oxycodone. it worked a little better on pain, but the side effects were awful!!! i was very sedated, moody, irritable and grumpy. the worst was at night i had a restless leg syndrome type of pain in my legs, and i could not stay asleep, even with sleep meds!!! i do not recommend this medication! i&#039;m looking into this genetic test i keep hearing about!"