"i was diagnosed bipolar 1 with psychotic features 3 years ago, but always dealt with grandiose thinking, mild delusions, a good deal of depression. after self medicating for two years i had a mental melt down and after spending 2 months cooped up in my apartment, anorexic, dying; i decided it was time to see a psychiatrist. the medications i was prescribed ranged from mood stabilizers to antipsychotics, benzo&#039;s, sleeping pills, many i was allergic to like depakote and trileptal. anyway at first i tried the regular seroquel but gained 40lbs in one month and slept 14 hours a day. switched to seroquel xr, not as tired, lost 20bs, appetite/ mental noise decreased, panic relief, strong sleep aide, life manageable, they are expensive. highly recommend."