"i&#039;ve been on for one week now, 75mg a day/3months. i have for the most part always had clear skin all of my life w/ an occasional pimple. i&#039;m 27 and just this year i&#039;ve been breaking out, cystic acne out of no where. i finally went to the derm after everything else failed. like i said, it&#039;s been a week and i can tell you this medicine is tricky. i have some side effects, abnominal pain, severe headaches, couple others, but i see a such a difference! the stuff stuck in my skin is coming out, it&#039;s not drying my skin like trentinoin did. i&#039;ve never been on medicine like this so take it at night before bed to avoid feeling some of the symptoms. avoid the sun+ any drinking when on this, it will make you vomit!"