"i have been on many pain/anti-inflammatory medications to help with rheumatoid arthritis, plantar fasciitis and a torn tendon in my shoulder.  it is the fastest acting and most effective pain relief i have tried (comparing to duexis, hydrocodone, prednisone, tramadol).  it does not cause stomach upset like other nsaids and the only side effect is sleepiness but, a quick nap and pain is much better and no grogginess."