"i have tried many antidepressants, including celexa (horrible, emotionally flat), cymbalta (rocked for 2 years, then stopped working) and several others.  i&#039;m a 26 year old male.  my prescribing nurse suggested i try pristiq.  she started me out at 100mg instead of the traditional 50mg.  she did this because i have a methamphetamine addiction as well (been clean 5 months).  this medication is amazing. it&#039;s only been 7 days, and on day 4 i really started to feel good. i can&#039;t wait to see the full effect!  by the way - to all the guys out there - i&#039;ve had no sexual/libido effects from this.  in fact, no side effects at all.  just feeling happier than i have in years, calm, energetic, and interested in life again.  love pristiq."