"i have been taking pristiq for just over a month now and i have to say it is amazing. i was experiencing severe depression, anxiety and suicidal thoughts. after only 5 days of being on it i felt completely back to my old self again. i cannot believe how fast it works. i am able to function normally at work, concentrate and have extremely high amounts of energy. i take mine in the evening and i find that i am staying up longer than normal. it is hard for me to fall asleep. i think i might switch to the mornings instead. otherwise no major side effects...a few headaches in the first 2 weeks but they are gone now. have a few hot flashes and night sweats from time to time. this medicine has helped me and i truly hope it helps you too. i feel great."