"i have little side effects like a headache, but that is due to no appetite from this medication. ever since i have been on it i feel wonderful again like i used to be. all i would sit around and cry and think i was useless but now that is gone all together. i&#039;m on 200mg and who knows i could have it increased if all goes well. since i have been on this medication i have lost 14 lbs. i have no appetite so i have to force myself to eat which isn&#039;t till like 4 pm. i&#039;m so glad i&#039;m losing weight and not gaining. who knows it could be a combination with my lisinopril. i guess everyone is different but give it a try or ask your doctor if you can take it for weight loss, my doctor put me on it for weight loss and depression...very very happy"