"i can&#039;t share much yet because i literally started this medication last sunday (today is thursday).  only have two complaints - the cost is the first one!  i hate that insurance won&#039;t cover this, and #2 (something i see no one else complain about!) is constipation!  it&#039;s awful.  just a few days in and i do take colace every day, plus i also take miralax.  i even took senna tablets last night and nothing.  ugh!  that&#039;s so uncomfortable.  i haven&#039;t weighed myself yet, i will do it this sunday and see if anything has been lost one week down."