"been on zoloft 3-4 months. the usual side effects. worst insomnia when i upped the dose from 50 to 100mg, which lasted about 2-3 weeks . insomnia returned when i upped to 150mg, but not as bad. i am at 150mg. i take it at 5-6am now, which knocks me out and i sleep additional 1-2 hours, in a very relaxed state. i kind of use it as a morning sleeping pill. if i take zoloft at 10pm, it has opposite  effect and i can&#039;t sleep. depression is mostly gone, generalized anxiety is completely gone, social anxiety is reduced significantly. it took 2 month for the anxiety to go away. for public speech i still use 40mg propranolol 1 hour before the event, and the results are overall great."