"i took cymbalta for anxiety and depression. over the years, i took anywhere from 30-120 mg. i think around 60 mg was most effective with fewest side effects, but i still experienced tons of anxiety while on it. at 120 mg, i had bizarre psychomotor symptoms - for example, in order to fall asleep, i had to rock back and forth. the same day that i decreased from 60 mg to 30 mg, i noticed the return of an ocd-style facial tic i hadn&#039;t had since middle school (i&#039;m 25). side effects included drastically increased sweating, &quot;brain zap&quot; headaches, and difficulty finding the right words (which may be permanent, as i&#039;ve been off cymbalta for 3 weeks and continue to experience it)."