"took remeron/mirtazapine few years ago for about one week &amp; gained about 15 (unwanted pounds). i just ate and slept so i stopped after a week! was taking it first thing in the morning at the time but this doc said take at night. i need the appetite stimulation now so i&#039;m prescribed it again. don&#039;t know if i could handle the ravenous, uncontrollable appetite it gives though and don&#039;t remember the effect on my depression as i was too consumed with eating. "