"i have major depression, anxiety and obsessive compulsive disorder.  most of the meds i tried over the last 14 years made me gain huge amounts of weight, killed my sex drive, had me twitching as i tried to sleep, or i had insomnia.  i found that to keep the worst side effects (not sleeping/poor sleep) at bay, i had to take lower doses that were barely managing my depression and anxiety and i was still gaining weight and had no sex drive.  my new dr. suggested viibryd.  i had minor gi issues and gas the first couple weeks but those have gone.  i am on 20mg/day and feel wonderful. i feel normal. no side effects!  seems from the reviews this is a love it or hate it medication.  i would recommend that anyone at least try it. "