"the first day when i woke up i felt like my body had been hit by a mack truck! but the second day, my body felt fine. it took about 2 weeks for side effects to go away (trouble sleeping, headache, stomach upset). the motivation has been wonderful. i take it with wellbutrin and lamictal. i never wanted to try it because of the weight gain but i have not found that to be true. in my case motivation = exercise."