"took with tramadol. first two days was fine and had a blast of energy!  then felt i was having allergic reaction. i switched the pristiq to night time before bed and took the tramadol in the morning and afternoon instead of at the same time. problems solved and no issues. after nearly a month of use i am starting to feel tired again and flat as opposed to the energy i was feeling when i first started.  the veterans administration covers my cost.  it just recently got approved but still requires a special authorization."