"i started celexa last april after having tried numerous other antidepressants. it took a good 6 weeks for me to really get the full effect of the medication, but it has changed my life.  i found it to be subtle, effective, and lasting without any side effects. i really think it&#039;s a matter of your personal brain chemistry whether an antidepressant will work for you.  it&#039;s worth it to keep trying to find one that fits for you."