"my dr. prescribed me 60 mg cymbalta 2 weeks ago to take everyday along with a 25mg antihistamine for anxiety. honestly, there seems to be more good than bad reviews so i&#039;m guessing i&#039;m a part of the small percent chance that it will have bad or little to no effect. the only thing cymbalta does for me is make me exaggerate a smile. i still feel exactly the same and my anxiety is still there. the antihistamine mainly takes care of the physical effects of anxiety but mentally i&#039;m still suffering. try it if you need to, i say it&#039;s worth a shot."