"i have severe gastroparesis and my abdominal pain has been very bad through the years but has gotten worse the past 2 years. i have taken all levels of lortab, tylenol #3 and demerol.  i would only take the demerol when i was having a flare up had break through pain.  about 10 months ago, my doctor asked me if i would try nucynta, that it was a newer pain medicine and does not cause the &quot;euphoric&quot; feeling.  i started off my taking 50 mg and would double up if pain was extremely bad.  this medicine has been great for me!  when i saw my pain management doctor for the 1st time, he upped my dosage to 75mg.  i average 2 a day.  it relieves my pain and i don&#039;t have any of the side effects.  i can even work when i take it and that is huge."