"this medication works great, my cycle has never been regular but on this i can pinpoint the day i start and end my cycle. i do get headaches the first day i put on my new patch so i just take advil as a preventive and that seems to do the job.. most of the time. this does help control acne as well, and have not experienced any weight gain and i have used it for over a year and a half. the patch site can itch but my skin seemed to get used to it after a month or so. i use it on my lower back above my pant line and switch sides weekly. this seems to be the best spot, except when i get asked what it is. lol! i was on the depo shot for a year and absolutely hated it, and can&#039;t remember to take a pill daily so this is a great alternative."