"i started taking orsythia about a month ago. since then, i&rsquo;ve been depressed and i have no clue why; i have also had more anxiety in the past month than i have had in the past 3. i read that others have had some anxiety and depression problems while on orsythia. however, i am not as overly-emotional as i was on the birth control that i was taking before this one. i&rsquo;d honestly be overly emotional 24/7 than depressed often. i don&rsquo;t have very noticeable cramps but tylenol helps take them away. i also have gained a couple pounds while on  orsythia. i would not recommend this to someone that has a history of anxiety/depression because it will drain you. many others have also had this problem while on orsythia"