"this is one of the most under rated drugs for depression.  i found it myself and every time i mention it to a new doctor, they have never heard of it.  i am afraid they will someday stop making it, which would be a tragedy. it saved my life--multiple times--when nothing else worked.  i&#039;d had every ssri in the book thrown at me (because, of course if one doesn&#039;t work, surely another of the same type will).  no weight gain--actual loss. pulls me out of suicidal despair within a few hours. i still have a bottle for emergencies.  for me, however, as a longterm treatment, it would start making me apathetic--not lethargic, just kind of nonchalant. after 3 days on it, i would want to quit my job. fast acting, low side effects, mildly energizing."