"female 5&#039;7&quot; 179lbs i started contrave on 5/7/17. i am going into week 3. as of now no significant weight loss. and my appetite is not as nearly diminished as i thought i would be. the first day it did i did not eat all day till dinner and even then it was a small portion. i drink water non stop, cut the soda, still allow myself one cup of coffee mon-fri. i do get a little nausea and slight headaches, but nothing to bad. i am someone who suffers from migraines but this is pill is not adding to them at all.. so that i am thankful for, no depression or anxiety so that is a plus. i have cut my food in take and i am eating smaller portions. i do go to the gym 3 times a week. i have a friend that lost 60lbs over an 8 month period. so i am hopeful"