"my entire spine was destroyed in a car accident 26 years ago, and i developed mps.  3 years ago i broke my neck during a seizure, causing additional pain.  avinza has done the best at controlling my pain; but while on kadian i was titrated from 120mg to 60mg by doctors who didn&#039;t believe i was really in pain.  now that they have mri&#039;s of the damage suffered 26 years ago that has degenerated over the years, they believe me and will finally titrate me up to 90mg of avinza, which is a wonder for me.  i also use several other means to control the pain, such as diversion, a spa, exercise, and relaxation response."