"i&#039;ve used phetermine off and on ...dry mouth and sleeping a little less is the worst side effect i&#039;ve experienced. i also recommend taking this medication very early in the morning. to help reduce the dry mouth i would recommend changing all liquid intake to water. this always helps me. you will become tolerant the longer you&#039;re on it, so establish weight loss goals early on. this is a very affordable pill and it helps motivate you to get started losing unwanted pounds. i take it five days a week and skip weekends. you need to find which is best for you. i&#039;ve always accomplished my weight loss goals using it as a weight loss booster."