"i was put on zoloft for major depression and general anxiety disorder after my baby was born about a year ago.  in general, it helped with my mood swings not being so intense, but i also found, over time, that it did not help me in stressful situations and i actually was more aggressive while taking zoloft.  i have also gained weight on this medication and am now 30lbs over my average weight.  some other side-effects have been dry mouth, anxiety in the mornings, more agitation, and an increase in anxiety-soothing habits (such as picking, scratching, obsessing over flaws, etc).  after taking zoloft for a year, i&#039;ve found that it&#039;s not really helping with my depression or especially my anxiety anymore. "