"when i use doxy, prescribed by my dermatologist it works well with occasional breakouts...problem is when i stop using, and dr makes me stop after being on for 3 months, go off for 1..well...my face explodes! severe acne all over..i&#039;m 40 yrs old and am so exhausted over trying to clear up my face. thank goodness i can cover up with make up. also i use retinol..ziana and a face wash also prescribed by dr at the time! frustrated."