"i was on paxil when my doctor switched me to brintellix 10 mg. the paxil had stopped helping with my anxiety and depression. i experienced the itchy skin for the first week but that subsided. i did experience some nausea but it went away also. i was on this medication for 4 months and at first it was great! i felt so much better however i started noticing my energy level was decreasing and weight gain. at my last dr appt, i had gained 8 pds in 2 wks which was a total of almost 25 pounds in 4 months!! needless to say, dr stopped medicine immediately and switched me again. so if you have a tendency to gain weight this medication may cause you to pick up pounds in a short amt of time!! even tho weight gain is not listed as a main side effect."