"i have severe joint pain (jaw, fingers, shoulders, elbows, knees) due to an autoimmune disease and nalbuphine saved my quality of life.  i took it as needed for pain almost daily for five years without any side effects and without ever having to increase the dose.  got a new insurance that wouldn&#039;t cover this medication and within six months i was on disability (vacillating between chronic pain and &quot;opiate stupor&quot;).  i am fighting to get this approved again, so i can rejoin life and resume the career i loved."