"started with 30mg plus ativan (lorazepam) 1-2mg/day for anxiety/depression.  ok.  then, up to 45.  too strong, down to 30.  later back to 45, then 60.  lots and lots of side effects--ear pain, weird nerve pains, mania, then urinary retention which is very serious. kept trying it too long, 7 weeks.  then switched to venlafaxine er which is much more tolerable."