"i have been on seroquel  (along with a myriad of other psychiatric medication) for 10 years at a dose of 600mg at night. for a while i would get so sedated that while sleeping i would stop breathing and jump awake feeling like i was drowning. while the medicine has been very helpful, i am starting to titrate it down in the hope of losing the 15kg that i put on when i started it. i now find it impossible to sleep without it so i&#039;m coming off it very slowly hoping that my other medicines will keep my mood balanced. overall a really good medication."