"i started off at 50 mg of sertraline  and after a few weeks i started feeling great, i felt more positive, i could sit and watch a whole show or movie with my family. i liked my job more but my appetite did decrease and it made me feel speedy which also made it hard to sleep. ok so fast forward to 1 month my dr. decides to up my dosage since it seemed to be agreeing with my body  ( i have depression but mostly anxiety) he upped the dosage to 100 mg tablets. after one week i was raging - my family noticed my colleagues noticed.  i felt like i was roided out. i was mean, aggressive and hard to be around. i also felt downl like i didn&#039;t want to be around people anymore. that quickly it all changed. made a same day appointment with the dr to switch meds."