"i took spiro for a total of 6 months for moderate hormonal acne around the jawline.  i started off taking 25mg for the first 6 weeks, and had a bad break out, than i increased to 50mg and had another bad breakout.  my skin only got worse using this medication and scarred easily and i got acne in places that i never got before.   also in the beginning i felt very tired and in a brain fog but got used to it i guess, since i have been off the medication for only 5 days i feel so much more awake and without it.  i was wondering why i was getting so forgetful, and now i realize it was the brain fog from the medication.  also made my skin very saggy and since being off it for only 5 days it has already improved.  only plus for me was i lost 3 poun"