"it took me a long time to realize some major changes in my life directly correlated with the time i began to take ortho tri-cyclen. i thought these were just general changes in my life until i realized they all started around the same time. i gained about 8-10 pounds, which is almost 10% of my body weight so it made a noticeable difference. the biggest negative point, however was the depression and irritability. i would cry for at least 2 days every month for no reason and considered dropping out of school and moving back home because i was so unhappy. since i stopped taking ortho tri-cyclen a month ago my whole life has gone back to normal, dropped 5 pounds and generally happy and comfortable. i never got pregnant, though."