"i take 50 mg of spironolactone twice daily for acne. my experience is very positive.

initially, i noticed light-headedness and pronounced diuretic effects. lost a couple of pounds of water weight. appetite and weight gain/loss are not affected.

my skin cleared within two to three weeks. i occasionally have a small pimple or blackhead that goes away in a day or two.

my periods are very irregular. i think since i started taking this drug i&#039;ve had one &quot;real&quot; period requiring the use of tampons. i do randomly spot/bleed from time to time. 

no mental health effects so far. if anything, i feel more stable due to the lack of periods and pms."