"i started taking this medicine when i was 16.  i am 26 now.  right now i take 100mgs.  i was an unhappy teenager and i can&#039;t say it did anything for me at that point in my life (but i was only taking 50mgs then).  i stayed on zoloft all through college and only went off of it for about 6 months, at the urging of a boyfriend at the time.  those months were bad.  i tried everything to feel better (exercise, meditation, different activities) but i always felt like there was blackness hanging over everything.  i couldn&#039;t function socially and became rather reclusive.  with the help of my therapist and psychiatrist, i went back on zoloft and my depressive symptoms decreased dramatically.  i have been on zoloft for 10 years now so it&#039;s just a part of my life.  i get sad sometimes, but when i get hopeless feelings i can process them more easily.  it&#039;s hard for me to imagine life without zoloft, but i hope to someday regulate my depression with a therapist and go off of it.  that said, i don&#039;t really have any side-effects to speak of.  sometimes i have a low sex drive, but its only at certain times of the month, like before my period.  however, having a diminished sex drive on antidepressants is easier than not having any drive whatsoever when you are off them. to me, taking zoloft is almost like taking a vitamin. it&#039;s no big deal."