"saphris changed my life - but not until i went to 10 mg.  i was finally &quot;normal&quot; - completely taking care of myself, my house, my business affairs .... i even realized i had hoarding tendencies and was able to rid my life of all the clutter.  then the wheels came off :  tardive dyskenisia.   i can&#039;t think of a more humiliating side effect, and it started a year before i finally got a second opinion and was diagnosed.  td worsened when i stopped taking saphris, and unfortunately for me, all my &quot;old&quot; habits are back.    it was so nice to be normal for the time it lasted -- but td is horrific, and a truly unfortunate side effect."