"i had severe acne when i was a teenager and took oral retinoids (accutane)  for a year. clear skin for a few years, and then the acne was back in a more mild version.

i am applying a pea sized amount of adaferin 0.1 for two months now and my skin went from mild acne-&gt; very dry skin and acne-&gt; just dry skin-&gt; normal skin with a few scars and occasional hormonal pimple.

i apply a pea sized amount of the cream in all of my face (my dermatologist said a lentil in each cheek), after i have removed make up and have washed it with a mild soap (no scrubs). you have to wait to apply the cream after you wash your face (15 min). wait a little bit more and apply moisturiser if needed. 
do not use locally just on one pimple. it works for preventing."