"i&#039;ve been on gianvi and its counterpart loryna for almost 5 years now and the closest thing to a side effect that i have had is sometimes i will have some spotting on the 3rd saturday of my pack (day 24). my period lasts 2 days at most and is super light. i have no more cramps, no more cysts, my skin is clear except for a random zit, and even having depression and anxiety i have no psychological symptoms even without anti-depressants. i am not sure what problems everyone else has had, but they are probably sensitive to an inactive ingredient in the pill like i was with the depo shot."