"i have taken a simple anti-depressant such as effexor for years. i never felt they fully did the job. when talking to my dr. one day, i told her my sleep patterns were horrible, with insomnia, or awaking early. she suggested seroquel as an additive. i have been on it for about a year, and i have never felt so rested. i have a better focus. i even think it has really helped my depression a bit. yes, it does increase my appetite a bit , but i try to eat healthy foods and walk. you must take it  a full 8 hours before you want to awake, or you may be droggy. i am really satisfied."