"i started contrave in october of 2016 with a starting weight of 159. in the beginning i didn&#039;t notice any changes, i actually felt like i was eating more for the first few weeks. i had a few side affects - headaches, nausea, constipation, hot flashes but those have since gone away. it&#039;s now feb 2017 and i&#039;m happy to say that i am down 25 pounds!!! very happy with the results"