"only recently has the makers of topamax been disclosing the potential risks of acidosis, renal tubular acidosis and bone disease. after being on this drug for 6 years or so, i developed kidney stones (another side effect) on five different occasions. my urine citrate levels dipped to 18. 550 and higher is normal. i had become so ill, i was close to renal failure. calium and vitamine d levels were dangerously low. my bones developed osteomalasia, or softening of the bones. "