"i swore that if zoloft worked for me, i would come back here and write a review. i hope this gives some people hope who are too scared to take it or try something new. i was first put on lexapro for serious anxiety, which then led to depression. i was on that for about 9 days. it was terrible! made my anxiety way worse, vomitting, couldn&#039;t sleep. so then i was put on pristiq. i took it one day (fast acting) and felt so weird, shaking out of control, sick to my stomach, etc. finally. i was put on 50mg of zoloft. i am on my 4th week of it now and i can honestly say i feel like myself again! only side effect was extremely tired. so i started taking it at night and that has helped! good luck!"