"i have been on saphris for three years. i loved how calm and focused i was. but i have gained 60 lbs.  i told my dr. a million times but she says it doesn&#039;t cause weight gain. well i am very depressed. i exercise i eat very little and i can&#039;t lose a pound. well now i am morbidly obese. and all the stuff i can&#039;t do because i&#039;m so big has really got me down. i am weaning my self down and getting off saphris as much as i hate the side effects i am scared to see what my life will look like with out it. oh my daughter was on it for two months and she gained 18lbs. why can&#039;t we have both sanity and without gaining 50 freaking pounds. grrr"