"i started off on 50mg once per day for 6 weeks. i noticed very little improvement in my acne but my skin was less oily. the only side effect i had on this dosage was cramping and spotting in between my periods. after 6 weeks my derm upped my dosage to two 50mg pills per day. my acne began to clear and my skin became dry for the first time in my life. i kind of enjoyed it while it lasted. the side effects worsened as my dosage increased. i had frequent urination, severe thirst, headaches, the cramping intensified slightly and i would occasionally become light headed. from the day i started this medication to 2 weeks after stopping i did not stop bleeding. literally constant bleeding. if it weren&#039;t for that, i&#039;d have continued with it!"