"at first, i took remeron and i was knocked out for a full day. i was underweight and had panic anxiety. this really helped me. after the first day my body seemed to adjust to remeron and by the 3rd day, i didn&#039;t have any tired feeling at all.  it definitely helped me with sleep.  i am now on 30 x 2 tabs a day and have been on this for years. i am actually afraid to get off of it. it has helped me through very difficult times."