"i have been on the combo of phentermine and topiramate for a month, i started at 180 lbs. i have lost 11 lbs, so now at 169 lbs....of course was hoping to loose more.  i probably need to exercise more.  i have had no side effects at all! i am watching what i eat and how much, i am drinking a lot of water and probably too much coffee (black) in the mornings, but i always do. i am on 37.5 mg tablet of phentermine, started on 1/4 tablet...now on 1/2.  i am taking 25 mg. of topiramate, started on 1 tablet...now i am taking 2. i have no insurance and i have noticed that some have been concerned about cost.  i have 2 scrips, about $20, google good rx for a coupon, most pharmacies accept it."