"i had tried for about 18+ months to find a medicine that would help my depression.  i bottomed out and was contemplating suicide.  my doc prescribed me trintellix.  i noticed a difference the very first day.  i was skeptical at first, but i got better and better as the days went on.  i had a few occasions of nausea, and even vomited once, but that all went away after about a month.  trintellix saved my life, literally."