"i was on both cymbalta dueloxetine and i would swing in and out of black moods and get very angry and uncontrollable. i&#039;m a small girl 5&quot;3 114lbs at the time and it took 3 full grown men to get me held down several times. we&#039;re now trying new medications after we discovered i was having seizures for months before starting the meds, it is a great medication to be on if it fits with you and your current medications. do your research thoroughly"