"i am stopping topamax after 3 months.  initially i lost 13lb pretty fast, within a couple weeks.  i was laid up with an injured back and sick so i wasn&#039;t moving, but then i wasn&#039;t really eating either.  since then i&#039;ve played with the same 5ib.  i am taking 100mg 2x day.  after about 6wks i got some of the common side effects (vision, memory, taste, exhaustion), i stopped losing weight.  but i&#039;m fairly certain it is the source of some pretty severe depression that didn&#039;t exist prior to taking it.  i&#039;m glad i lost 13lb, but the depression is too much to handle and i&#039;m throwing in the towel.  wish it had been more effective, but really it stopped working after about 3 weeks anyhow."