"i took this with bupropion.  i stopped bupropion, because i was so edgy and irritable. it was suggested i wait for prozac to take full effect in about 1 month. i stopped prozac last night after a week of it alone.  i was edgy, irritable, and didn&#039;t feel like doing productive things like care about my job, or care about studying on investing choices. i just wanted to take a nap to relieve the buzzing in my head.  today i am not taking anything.  i feel better than yesterday. "