"i was prescribed cymbalta as a preventative for intractable migraines. i was also dealing with some depression due to my chronic pain. 
i was on a dose of 20mg at bed and was to increase to 40mg after 2 weeks. after my first dose, i awoke with general nausea. i had diarrhea once that 1st day. after my 2nd dose the worst of it started. i awoke three times that night with diarrhea - literally. i didn&#039;t wake up having to run to the the bathroom. i was awakened because i was in the process of soiling myself in bed. i couldn&#039;t eat, lost 5lbs in a week, had diarrhea the whole time. i stopped talking it and had the worst migraine of my life and electric zaps for two days after. just say no to cymbalta."