"i took vortioxetine for six weeks and it was a horrendous experience. nausea would set in within minutes after taking my daily dose. i vomited after taking the first dose at 10mg and after my first dose at 20mg. the nausea was so bad that it was actually making me feel worse. i did experience a few days of elevated mood at the end of my six week trial, but that&#039;s because i was excited to be done with it and stop taking it. worst antidepressant i&#039;ve tried. (on my 10th now)"