"i have been off and on cymbalta for over a year now. during a really stressful time in my life i was started on zoloft and then klonopin. the zoloft gave me restless legs and klonopin made me severely depressed. after a period of nothing my doctor suggested cymbalta. after just a few days things got so much better. i relaxed and was able to eat and sleep normally again. the side effects were very minimal and lasted less than a week. after hearing horror stories of stopping zoloft. i quit by counting the granules and tapering down over a couple of months. it worked fine for me. i usually try to take it around noon with lunch for the best sleep at night."