"i am currently taking norco 10/325 for neck and lower back disc problem. it works right away but is short term. i tried tramadol 50mg and found it takes awhile to kick in and makes me feel sluggish. i also had to take more than instructed to get similar relief which gave me a headache. please be careful as the withdrawl effects are very unpleasant and make you sick. i am staying with the norco, as it works for me."