"i have been taking wellbutrin continuously for 20 years. if it were not for this miracle drug i would be dead. there is no doubt in my mind that my intractable depression was arrested with wellbutrin. i have a chemical imbalance that is permanent, i once went off wellbutrin for a month because i was taking another medicine, within three weeks i was having suicidal ideas. needless to say i will not go off it again, my doctor assures me it is safe for lifelong use."