"after trying just about every other medicine out there, this has, by far, been the most effective from an emotional, cognitive, and mental standpoint; however, i am sad to say that i have made the decision to discontinue due to weight gain (15 pounds-ish).  i gained weight when i first started the medication at 5mg (also had a severe rash on my stomach), with the weight-gain increasing almost immediately after jumping up to 10 mg.  the weight gain is the only reason that i am discontinuing.  (some fyi&#039;s.  i must take this medicine with food or i will be sick.  i also take it right before bed as it makes me tired, and also take lamictal, trazadone, buspar, and ritalin)."