"i&#039;m 24 and have been using acanya since i was 18. i remember noticing a difference within the first few days and massive improvement within a few weeks-1 month? don&#039;t really remember, however, this product has remained relatively effective for 6 years for me. skin is 90% clear other than cysts when i am highly stressed or due to hormones :/ this medication only gets 9/10 because i still get blackheads and cysts occationally and it&#039;s very expensive"