"i am a 50 year old female who started taking contrave about 6 weeks ago to help with weight loss.  the first month, i admit, i could not tell a difference. i suffered no adverse side effects at all, just not a decrease in hunger/cravings/etc.  at week 4 or 5, i began to notice a drastic decrease in my appetite and &quot;nervous&quot; eating behaviors.  slow start, but i am happy with results - lost almost 20 pounds - and i am not hungry!!  hang in there; it works."