"i began contrave in early 2015, and as of july i have lost 25 pounds. this is significant because i was not very big to begin with, and i stopped taking the medicine for a few months in the middle. i began as recommended, and the side effects hit me immediately. i was nauseous, constantly tired, had abdominal pain, lack of focus, and i became sick any time i put any food in my mouth. i guess it was a great way to lose weight, but not the way i wanted to do it. i was miserable. so i quit for a while, but decided to give it a second chance. i did not increase my dosage as quickly, and i only went up to 2 pills a day. i still have occasional loss of concentration and fatigue, but it is no where near as bad, and i&#039;m losing weight."