"i&#039;ve been on tri sprintec for about 3 or 4 years. it regulated my period and made my cramps disappear. i can pinpoint when i&#039;m getting my period to the day since my second month on it.  i had to skip a month one time but the next month my period went back to the schedule it has been on for years. it cleared up my acne as well, but took a couple months."