"i wanted to rate this an 8.5.  not sure why.  i have tried numerous medications for the past 15 years with many side effects or no effectiveness.  wellbutrin xl(300 mg) seems to work best for me. i have a lot more energy now where i was sleeping all weekend before.  i can live with my side effects at this point.  my appetite isn&#039;t very good but on the positive, i have lost weight and feel better about myself.  i now have trouble sleeping, my heart rate has increased usually about 7 hours after i take it causing anxiety symptoms, sometimes my head is a little foggy and my memory recall is slow but i will accept these because of the energy and ability for me to now accomplish what i wasn&#039;t able to before."