"i was taking ortho-tri cycles lo for many years. i don&#039;t recall having any problems. up until last year, for some reason my prescription changed to trinessa because it was the &quot;generic&quot; version of ortho. i went back to the doctors to get a refill last month and they put me on another generic brand this time of trinessa. within the first week of taking it i was getting bad migraines. the second and third week i was feeling nauseous all day with also bad stomach pain. i noticed i was feeling depressed and unmotivated. one thing that scared me was my mood swings. i wasn&#039;t aware of it at all until my boyfriend said i went from being happy to irritable within minutes. after not even a full month of taking this pill, i will be switching."