"i had arthrodesis surgery to fix my crushed right thumb 08-03-2010, and have had severe pain in it ever since.  the doc prescribed hydrocodone and oxycodone, which worked very well.  so i would not become addicted to those, he switched me to tramadol, 50mg, 2 every 4 to 6 hours as needed.  first time i took them, before bed, i had a terrible night.  normally, i&#039;m a sound sleeper, but i tossed and turned and did not get a wink of sleep, which is not one of the published side effects.  so, that first time was my last.  meanwhile, i&#039;m in pain."