"i had a severe traumatic brain injury (tbi) in 2006, since then we have tried multiple medications to control anger.  depakote,  topamax, klonapin, zoloft etc etc.   none of them worked .  i have been in rages to where i don&#039;t want to be around anyone or talk. it&#039;s been 10 years now and i happened to go to a doctor in a small town and told her everything about my anger etc . she prescribed gabapentin along with cymbalta and i have felt the greatest change. i go outdoors and hike, fish , feel like i am living again. still i will have my bad days but this medicine i highly recommend to people who suffer with anger/irritability.   i completely understand that we are all different and medicines work differently and i truly hope the best for you reading this."