"i have been on fentanyl for about 3 years due to spinal fractures. this is the only medication that has given me any relief. on a scale of 1-10 i would rate my pain at a 2-3 now, where as before it was a 7. i am currently on 37 mcg/hr (1 x 25 mcg patch and 1 x 12 mcg patch). i have only two issues with the medication. first is that occasionally it causes extreme nausea (this usually occurs the day after applying a new patch) and blisters on my back where i applied the patches. however, this is probably due to sensitivity to the adhesive and not the medication. even with these issues, the positives far outweigh the negatives with me."