"i have been on nardil for 30 years because of depression, panic attacks and severe anxiety.  i did gain weight while taking nardil, but after 6 months after i started nardil, i began to have good days again.  for me, nardil took a long time to begin working to ease my depression, etc.  i also take one, 5 mg of valium.  i am a senior citizen and at times it does concern me about continuing the nardil, but as long as it keeps working and i see my psychiatrist regularly, i have faith i will be okay.  sure, i have a few &quot;down&quot; days here and there, but never like it was before i was put on nardil long ago.  (i had taken other &quot;older&quot; antidepressants...none of them worked until the nardil was prescribed).  a side effect i have is intense sweating."