"began last year and took for 4 months successfully. lost about 12 to 16 lbs easily. victoza suppressed my appetite by the means explained in the literature; apparently my stomach contents are slow to pass through to the small intestine, so the sensation of fullness remains. constipation is my main problem. when titrating up i experience gerd and some discomfort; this has probably kept me awake 2 or 3 nights total. after discontinuing in 2016 i restarted again this july 2017 with the same successful results (i had gained weight back through my own carelessness). i have lost about 10 lbs in 2 weeks, not a healthy rate, perhaps, but it reflects my appetite suppression. be careful when titrating up. i am back at 1.8 now."