"i&#039;m 41 and started having acne problems in my mid-30s. lots of little bumps and zits. after years of it getting worse, despite efforts with proactiv etc, i finally went to a dermatologist. i have been on this medication for about 5 months, plus azelaic acid in the morning and tretinoin at night. this combination is working - my skin is nearly clear! downsides: it does hurt the stomach a bit on an empty stomach. recently i&#039;ve had an yeast infection, so i laid off the antibiotic for a few days to see what would happen - zits started sneaking back, so now i&#039;m downing yoghurt, and slathering on the sunscreen...so worth it!"