"be careful!!!  never experienced major side effects from medication until now.  i ended up in the er within 2 hours of taking latuda due to severe muscle spasms.  my face contorted in all kinds of weird ways that is hard to describe.  i looked like i had a halloween mask on it was terrifying.  i have general anxiety disorder with spurts of depression depending on life&#039;s circumstances.  my dr. prescribed me latuda to take with pristiq because i had 1 seizure while taking other meds and had to stop taking after 10 years of success when it was needed.  the seizure could have been caused by anything as i was on the meds for months when i had it.  i took 20mg of latuda for the 1st week, 40 next 3 weeks.  my chin is completely numb permanently."