"i started using depo when i was 15 and was on it for about 5 or so years and again awhile later. i loved it, had no periods, no side effects, no increase in acne. i didn&#039;t gain weight until i started it again around the time i turned 21 and i think it was just the birthday, not the depo and stopped taking it around 22-23. now, i am 25 and started again. i am on my first 3 month injection and my hormones have been absolutely nuts. i am driving my boyfriend insane, crying and complaining all the time about nothing really. i am halfway through this cycle and will not be getting another injection. over the last month, i feel like a completely different person. "