"before skyla i&#039;d been on the depo shot for 9 months. i&#039;d had bouts with weight gain (20 lbs!) &amp; depression while on it, so i decided to switch to skyla. had it inserted 11/20. took a vicodin before the procedure (didn&#039;t seem to help much). the procedure itself was fairly uncomfortable and painful. it wasn&#039;t debilitating pain for me - just uncomfortable with two sharp cramps (maybe a 8/10 on the pain scale, but they only lasted 30 seconds or less combined). i got it inserted at 4pm and was having 7/10 cramps the rest of the night, took some tylenol pm and slept like a baby. woke up the next morning without any pain at all! been having 3/10 cramps last few days, but that&#039;s it. hardly any spotting."