"i went from talking 120mgs of cymbalta to taking 150 mgs of seroquel xr just over one year ago. i fortunately did not suffer from any if the initial side effects that i&#039;ve now researched &amp; have learned are really common when starting this medication. however, 1 month ago, i&#039;m not sure why but i ended up missing 2 nightly doses. what i experienced was nothing short of being in hell, literally. i physically was incapable of movement, getting up to simply get to the restroom was near impossible, every muscle in my body was weak &amp; near useless. i couldn&#039;t do anything but remain in a fetal position curled up on my side for the duration of over 12 hours. my head was cloudy, confused &amp; unable to process any thought. after this experience, i want off"