"i am having seroquel blues. just recently my normal dosage of 400mg went 200mg more and that 200 i must take during the day. i am so frustrated trying to find out how long does it take for the body to get used to taking the medication during the day. i always feel like i am in slow motion and unable to be patient with others, having irritability and have to take naps during the day to overcome the drowsiness. i know this medicine is important because it helps with the mania, paranoia, and suicidal ideation. "