"i started this medicine while breaking out with severe cystic acne for my adult life. i took this medicine for the past year, 1 year total. my face cleared up, but i gained 25 lbs in one year. no other medicine changes. i could deal with the weight, but when i came to the er with terrible abdominal pain, i knew something was wrong. i have an ovarian cyst now, and have to hope it doesn&#039;t rupture. make sure you are willing to accept the risks of having clear skin, as this can apparently happen to anyone who takes spironolactone."