"first of all, i am an md and very familiar with the meds in contrave. i was actually prescribing it before i decided to try it myself. i have been 20-30lbs overweight for as long as i can now remember (at least 20 years). i had developed mild type 2 diabetes, elevated cholesterol and hypertension. i was taking a handful of pills everyday at age 45. so i started the medication 24 days ago. my weight was 184. on some of the early days i had some nausea but it always went away. i was irritable at times, and some days when i literally forgot to eat i would get jittery and feel bad (but not hungry) because i&#039;m sure my blood sugar was low. so my results so far: today i am 165.8. i am down 18 lbs in 24 days. bmi down 3 points. this is no gimmick!"