"i&#039;m an african american female  20 yr old female &amp; i&#039;ve had acne since high school.recently , this summer , i was prescribed the doxycycline 150mg to take once a day . originally , the summer before i was prescribed another formula of doxycycline , to take twice daily . i took two pills at once by accident and about 45 minutes later , i threw up. even though , i didn&#039;t take the correct dose , i could still tell this pill was not going to sit well in my stomach . the formula (150mg) i am taking now is much better. it was a struggle hanging in there for the first month because my body had to get used to it . but i did . i advice to eat with food or on a full stomach. hang in there. i&#039;m waiting on my second refill . definetly see results ."