"i&#039;ve been on tri-sprintec for years and my period is extremely regular and i get it on the same day every month. acne has always been an issue, but it has definitely lightened up a bit since taking this birth control. if i miss a pill, my body lets me know. i get very nauseous and experience cramping just because i am so (reliant) in a sense, on it. also, i never had any significant weight change at all while taking it. i also have gone up a cup size too! i&#039;ve had no trouble with tri-sprintec and would recommend it to others."