"was diagnosed with bipolar 1 12 yrs ago, took neurontin, lexapro &amp; seroquel for 2 yrs with no problems. my p doc moved; new one weaned me off lexapro &amp; added lamictal. i started getting fevers, stopped lamictal, fevers more frequent &amp; higher, til i woke up in an er. long story short, found out a month later i had nms (neuroleptic malignant syndrome). my highest fever was 109 deg f. pdoc took me off seroquel, fevers continued a while. tried lamictal alone, got stevens-johnson syndrome. result, i can&#039;t take any antipsychotics. have some brain damage; can&#039;t go outside in hot weather, high blood pressure. had bad depression, then manic episode, no sleep 8 days, therapist said i was psychotic. this was last 10 days ago. just started trileptal. this is my last-ditch resort."