"i have been on various anti depressants since my late teens. everything&#039;s from fluoxetine citalopram, clomipramine and in a full breakdown; a combination of mirtazapine and effexor. it was this last one which took me sky high and so i stopped, also due to 30kg weight gain. after a couple of months i was suicidal and because i was diagnosed with bipolar since the mania on the antidepressants i was recommended going on to a cocktail of quetiapine, depakote and lithium. no way was i taking that with the side effects and the horror stories about weight gain as i&#039;ve lost the 30kg in weight i put on. lamotrigine i heard was the only one for helping without the weight gain so i gave it a go. it took about 2 months but it works a treat now on 300mg"