"i have suffered from anxiety and depression for the better part of 60 years. anxiety was normal for me until a friend told me about deplin&#039;s l-methylfolate. she explained that severe anxiety  could be from an inability to absorb folate. i asked my dr for an rx and he said it wouldn&#039;t hurt to try this it was a medical food and not a drug. i was on ativan, prozac, doxepin and trazadone and still had anxiety 24/7. within one week of taking l-methylfolate, i had absolutely no anxiety. it was so quiet in my soul that i almost felt anxiety about not having anxiety! it was foreign to me; the steady drip, drip, drip of adrenalin rushing through my system was shut off. within six months i was off all other medications. this was a miracle for me."