"i have been taking opana 30mg since last month and it is a very effective drug.  it has given me relief that lasts, usually 12 to 18 hours, which is something that my vicodin 10 had stopped doing.  occasionally i will take one and for maybe an hour or two i will feel relief and then nothing, usually i will go back and take another one and it will work.  i read somewhere that sometimes they go directly through your system without working.  what i really like about the medication is that i am mobile, upright and able to go about my day without feeling drugged and cloudy.  the only downside is the cost, 20 pills were $220.00 and 56 were almost $600.  currently, i have a $40. co-pay on insurance, but soon my insurance will be terminated."