"i haven&#039;t seen anyone else discuss this, but latuda gave me a lot of anxiety.  within 2 hours after taking the medication i would be in full freak out mode.  also, my lower legs felt tingly.  these issues tended to last anywhere from 2-7 hours after i took it (at 4pm).  i gave it a 3 because i think it was otherwise working for what i&#039;d hoped. my irritability disappeared completely.  however, because of the side-effects i&#039;m off and looking for something else. (i also take lithium and lamictal)."