"emsam is by far the best antidepressant i have come across in over 20 years of treatment in which i have been given everything under the sun. welbutrin was ok but was weak, edgy and stops working after about 6 months. i have been on emsam twice now for stints of about a year each. unlike other antidepressants it doesn&#039;t have that plastic, fake agitaged feeling to it. feels like natural emotions. it cuts my depression roughly in half. still suicidal often, but not every moment of every day. i have a severe skin reaction to the adhessive that looks horrific but its worth it. other than that and worsening insomnia it really doesn&#039;t have side effects. well worth the rash. i have to stay at 6mg because the higher doses produce psychosis in me."