"i was on the depo injections for around 2 years during uni, having previously been on the microgynon pill. in many ways, it was perfect for me- it completely stopped my periods, which was so convenient, and i had no cramps or pain at all. the problem was, my skin gradually got worse and worse, and stupidly at the time, i didn&#039;t put it down to the depo. i had always had mild acne, but the depo made it so much worse and just constant. finally, i was taken off depo due to possible bone density issues for long-term use (over 2 years), and switched to yasmin, which cleared my skin up completely! i know other people who had depo and it didn&#039;t affect their skin at all, so i think it depends on your hormones personally. as bc alone it was ideal!"