"i am hearted by the 6 reviews. i have just started on deplin. i have been on remeron for two years. i cannot tolerate serotonin type medicines such as prozac, lexapro. remeron worked beautifully at first but effects have slowly worn off and my anxiety and mild depression returned. i pray deplin will work for me and i can regain my enthusiasm and joy in life. i am happy for those of you who have been helped. wish me luck."