"i found this medicine to be very effective. of course, everyone&#039;s tolerance to pain medication is different, but for me, when tylenol #3, vicodin, naproxen sodium, and ibuprofen didn&#039;t seem to help even in the slightest bit, but tramadol was a great relief for me. i am grateful to find something that helped my chronic pain problem. i am very careful to only use it when necessary for pain."