"wellbutrin xl helped my depression tremendously.  i wish i had started taking it sooner when my husband became ill.  it also helped me to lose about 40lbs.  i contributed to the weight loss though by changing my eating habits and working out.  i started out at 150 mg, then a couple years later went to 300 mg, then just recently my husband passed away and the dose was upped to 450 mg which is the maximum.  i haven&#039;t started the higher dose yet, and am a little scared after reading all the side effects.  however, i never had any negative side effects with the other doses.  time will tell.  i will get back to you all about the results."