"i have suffered from mdd, gad, sad, ocd, panic attacks, agoraphobia and ptsd for the past 25 years. i have tried several other ssris and was recently switched to effexor xr. i was prescribed 37.5 and was to build up to 150mgs. the side effects were so severe i could not get past the initial dose. i took it for the past 6 weeks and it abruptly quit working. i could not tolerate increasing to 75mg. i will be switching to celexa. the side effects include tachycardia, sweating, hypostatic, extreme blurry vision, nausea, headaches, insomnia and weight gain of 5lbs. i experienced &quot;spatial disorientation&quot; where i would get waves of vertigo. i had great depression relief for about 3 weeks but the side effects were too numerous to tolerate."