"i been taking vyvanse a little over 2 yrs. this is the only medicine i have taken for adhd. as of this posting i have been off it 3 days. the first 18 months i thought vyvanse was the best thing sense sliced bread. the last 6  mths have been an emotional roller coaster of side effects. i have spent hours on the floor crying, my social life is none, i didn&#039;t talk to anyone but the people at work that i couldn&#039;t avoid, my husband wants a divorce and nothing made me happy, i was sad and depressed all the time. please be careful taking this medicine. i don&#039;t think it was meant for long term use or maybe it just affects different people in different ways. after 3 days in bed i&#039;m finally getting back to normal."