"i&#039;m 19 and have been on depo for about 1.5 years. yes i get moody, but i have a mood disorder so it could be that. yes i break out but its not absolutely horrible and i kind of always have had acne. i think i may have spotted a couple of times but only for a couple of days (so far). unsure about bone density since i haven&#039;t had a test done yet. i love not having a period or having to remember to take something more often than every 3 months. i think it&#039;s important to keep on schedule with it (none of this off and on stuff). no weight gain at all on it. definitely no lowered sex drive. only complaint: it can be scary not getting your period. but you can always take a test. also remember, its different for everyone."