"i have been taking remeron for a month now for depression, anxiety, loss of appetite and insomnia.  i have experienced a red swelling burning sensation in my face and neck - almost like a sunburn, painful, lasting at least two days then still feeling a little sensitive in my face and neck. my sleep is better, however there are still nights when it takes me a couple of hours to fall asleep, other times i go out like a light.  my appetite is better and i am not as anxious  anymore.  i have tried many other anti-depressants and remeron(30mg) is the best for me by far.  i only hope that the face problem goes away.  i did read a comment here by someone who was experiencing facial edema.  in the monograph it does allude to this."