"i have a cyst along my spine with a messed up disc. the codeine based medicines side effects were terrible. nucynta  75mg. 3 x day works wonders. i only take it when i do a lot of work which affects my lower back. my wife likes me to take it as i am not as grumpy. like all medicines some work for certain people and not for others. for me nucynta and demoral work best with min. side effects"