"i have been using saphris for about three weeks. my psychiatrist changed me from abilify. she started me on a low dose (5 mg) and took me off abilify and raised my lamictal. i had a very hard few days. she increased my dose to 20 mg and i now feel as stable as i did with abilify. it&#039;s still early. she also put me on clonidine (low dose) for post traumatic stress disorder and that helped and is helping my blood pressure as well! the only negative thing i have to say is the packaging is bad. someone needs to package it in a container that doesn&#039;t take the jaws it&#039;s life to try it open and then you have to try very hard to peel the covering off each individual tab. whew."