"i have been taking seasonique pretty much since it first came out about 7 years ago, and i&#039;ve never had any spotting or negative side effects at all. my period usually starts the friday after i start the inactive pills and is completely over within 3 days. i have always had awful cramps and mood swings, and the seasonique doesn&#039;t help much with those, but it&#039;s not so bad when it&#039;s only 4 times a year. overall, this pill is amazing. it used to be pretty expensive, but now it&#039;s only $20 with my insurance. split over 3 months that is really cheap!"