"i have been on 150mg of wellbutrin xl for two days and i can already feel a difference. it has removed all appetite which seems to be a side effect but, in all fairness, i didn&#039;t have one before i started taking the meds! i have depression and panic attacks and after just 48 hours i am excited about the holidays! baked five dozen christmas cookies today! i haven&#039;t been interested in the holiday season in years! i do recommend getting the brand name meds and not the generic, as i have heard many issues arising from the generic form. happy holidays!"