"i was on this method of birth control from age 16-20. i loved it! i never noticed a weight gain, no periods at all for this entire time. in retrospect that probably isn&#039;t healthy but at the time it didn&#039;t bother me in the slightest. i had pretty intense mood swings, but i was also in a very unstable relationship at the time so i&#039;m not going to pin the mood swings entirely on the depo. i recently switched to trinessa pills and absolutely hate them, i never realized how happy i was with the depo shot until i started something else. i&#039;m slightly concerned with the long term effects of the shot, but i might end up switching back to it. i know it has a rep for making people gain crazy weight, but it didn&#039;t have that effect on me."