"i have been taking percocet 10/650 off and on for about 5 months for back pain and for joint pain, tendinitis, etc. it works great for me despite my tendency toward resistance to pain medicines. i take one when i really need it and sleep great or do whatever i need to do. the only real down side i can list is when taking it before bed i am inclined to oversleep and feel groggy the next day."