"i have had acne since i was 11 years old. it is mild and only on my face, but it has always been very, very stubborn. i went on rounds of minocycline with very little relief. when i went on birth control, the acne cleared about 70% and all that was left were stubborn breakouts on my chin and around my jawline. i didn&#039;t want to start college with poor skin, so i went to a new dermatologist who told me the acne was hormonal and started me on spironolactone (50 mg/day) and differin (a topical). i experienced the initial break out. i developed new pimples for about two days but then called my dr. and got doxycycline (200mg/day). all in all, it lasted about a week. 3 wks in, my skin is beautiful. it glows and is so soft. ask your doctor!"