"when my doctor prescribed me epiduo, he had me taking it with doxycycline hyclate. now, i don&#039;t know which one is working. but i do know that epiduo is giving me near constant sunburn. the doctor said to put on sunscreen right before i go outside at all, and again every hour i am outside. who is going to be able to take sunscreen with them all the time? i&#039;m in cross country at my high school, and i can&#039;t just stop in the middle of practice to put on sunscreen! but, it did help my acne a lot. it&#039;s still there, but not nearly as bad as it was before."