"i started taking 50mg generic sertraline about 2 weeks ago.  i have had a very good experience with it and i love it. thank god for this medicine and the improvements that it makes on the brain chemistry. only experienced diarrhea for 1 day (which was okay for me because i&#039;ve always struggled with constipation which only contributed to fatigue and depression). i&#039;m more social (before i didn&#039;t care about doing much, even though i wanted to go out, when it came time to, i would end up going to bed), more easy going, less irritable and cranky. so much more patient with my kids. no side effects for me. oh and i&#039;m not eating ravenously at night because of stress and anxiety like i used to so it&#039;s helping me lose weight. yay!"