"i started taking effexol 4 years ago to take the edge off my anxiety because my job is stressful and i have to shoulder a lot of responsibility.  i am on a daily 75mg dose. overall, i have found it to be a great leveller, but the consequences of missing one dose is bad... missing 2 or 3 is pretty horrific, with head shocks, disorientation and feeling miserable. really miserable. it&#039;s good medication, but do not forget it if you are travelling."