"i&#039;ve been on this medication for several years now.  during winter months we up my dose and in spring reduce it. after about 12 years of trying ssri&#039;s and not having a lot of success we tried this drug.  it has been the best medication for my depression.  there are a number of precautions that you must remember to take.  #1  challenge each doctor to check and see if a new medication will react badly to the emsam, a lot of the medications have interaction with emsam.  also you must give up aged things, like pepperoni, salomi, beer, wine, and worchester and soy sauces.  i learned the hard way about the last 2.  most important thing is challenge all new medications and make the doctor look them up.  "