"i am 39 and have bad cystic acne along my jawline. my dermatologist prescribed me to take 100mg a day for 3 months. the first month i saw no change and did flare up as others have mentioned. by the end of month 2, my skin looked incredible. i stopped after 3 months because this drugs completely screwed with my libido. i used to be very sexually active with my husband and after taking this drug my libido has dropped in such a drastic manner. whatever you do, do not stop taking this drug cold turkey. you will swell up and retain water for 3 weeks. ensure that you taper yourself off. i have now been off the drug for 5 months and my skin is back to being as oily as ever and the acne has returned. my next step will be accutane or minocyclin."