"this new pristiq has worked wonders for me. i have tried practically every anti-depressant medication out there. i have bipolar 2 disorder, and most of the time, taking an anti-depressant alone without a mood stabilizer always set off severe mania. that has not been the case with pristiq. not only do i feel a million times better in every way, this drug has really decreased my appetite and i have definitely lost at least 10- 15 pounds since i started taking it about 7 weeks ago. i also take a little bit of xanax to better manage my anxiety. however, that only enhances the already great results that i have experienced with pristiq."