"i had bad to moderate acne for 15 years and that was with on and off visits to a dermatologist for about 7 years with nothing else really working. i was on accutane and had some negative side effects. but just about a year ago i went on spironolactone 50mg-100 per day, and loved the results within a three weeks, my skin got way better and less oil production. but my dermatologist keeps trying to take me off it. i have to beg him to keep me on it and he only lets me take 50mg every other day (this does help as my skin is staying pretty good). but i have to admit i am jealous other people get to stay on it and higher doses."