"i had tried just about every over the counter medicine available for acne for about three years.  i then went to a dermatologist who prescribed solodyn w/ epiduo.  i could see a distinct improvement with 2-3 weeks and at 3 months my skin looks almost totally clear.  my dermatologist prescribed for 2 months, and at my second visit prescribed for another two months.  i am nervous about coming off of solodyn, because it has worked fantastically, but it is so expensive and the coupon the company offers only has a limited number of refills.  other than the prohibitive cost (retail w/o a coupon), solodyn gets my highest rating!  my experience with solodyn.....be patient and you will see results."