"just started taking this for depression/anxiety, so far, so good. the first few days, i could definitely feel the stimulant effect, but on day 5, i can barely feel anything. obviously, it&#039;s too early to tell how it will help with anxiety/depression. i had just a hint of a headache, but nothing bad enough to even take anything for. no real trouble sleeping. i will be increasing the 150mg to 300mg (twice daily) saturday, so i&#039;m sure there will be another adjustment period then. i&#039;ve heard it&#039;s important to take the second dose fairly early in the afternoon (around 3 or 4), so it doesn&#039;t keep you up. at first, i did not think this would work with my anxiety, but it&#039;s mostly gone due to my body adjusting."