"i&rsquo;ve been on mirtazapine for about three - four years now. in the beginning i was groggy throughout the day &amp; i have gained quite a bit of weight, but it&rsquo;s worked wonders for my depression. i find it&rsquo;s less effective against the anxiety, for which i am taking quetiapine &amp; propranolol. it has a sedative effect so i take it before bed. i also found though, with this medication i would have bizarre dreams that felt very, very real. overall, very little side effects &amp; wonderful at tackling my depression. but again - wouldn&rsquo;t use this for anxiety."