"i am 19 years old and have been taking tri-sprintec for about a 1.5 years.  haven&#039;t got pregnant thus far.  so i&#039;d say its working wonders!  i know that on my last week on my birth control my period will come on a tuesday to wednesday.  it is so nice to know that i don&#039;t have to worry when my period will come.  i didn&#039;t have any complications my first few months taking it. have never had weight gain.  a week before my period i do develop breast tenderness. about the only downside to it."