"i took quetiapine (seroquel) for a little over a year. the pro&#039;s of this medication are that it helps me sleep and seems to tackle bipolar depression quite nicely. it also seems to make me less volatile and capricious. the con&#039;s unfortunately became too much. i gained over 50 pounds during my time on the drug, my blood pressure sky-rocketed and no amount of healthy eating or exercise helped me lose weight and keep it off. i have the appetite of a racehorse when i take it in the evening and my binging became dangerous. i also sustained a number of injuries to my legs and feet because my body couldn&#039;t keep up with the rapid weight gain during exercise. it&#039;s a good med, but be mindful that it causes weight gain!"