"hi, 36 year old male here.  i&#039;ve been on strattera for 2 weeks already and so far so good.  my metabolism has always been fast so i noticed an improvement on the 1st day!  i was able to concentrate and focus at work and it has enabled me to focus in class(i&#039;m in grad school).  for me, the medicine kicks in about 1/2 hour after i take it and for the first 10-15 minutes or so, i get a sort of sleepy feeling but once i start a mental activity, it goes away.  its very weird because i tried to take it at night and although it gives me that &quot;sleepy&quot; feeling, the medicine keeps my brain awake.  one time i took it at 9pm and i couldn&#039;t fall asleep till 4am!  after that event, i just find it better to take it in the morning after my workout."