"started at 18, was active, normal weight. started gaining weight right away but didn&#039;t think much of it until i realized i was having to buy larger sizes, but didn&#039;t seem to have bc alternatives as i&#039;m forgetful so pills wouldn&#039;t work. over the course of 5 years, i have gained over 100 lbs, hair started greying early, loss of energy, loss of interest in life, and thinning hair, dry skin. basically depo put me into menopause state, i was early 20s and felt decades older. i went from a size 12 to a size 24. and now 2 decades later, i still have that extra weight on me-no matter what it just won&#039;t come off! i am tired all the time, i hardly eat but still gain weight  easily. depo ruined my life, it took me as a young adult and made me old."