"lamotrigine has worked for me, i&#039;m bipolar 2 and other meds have been ineffective.  i have been on 100mg a day for three years with a break for pregnancy.  i have had spots at the times of dose increases and headaches when i have forgotten to take it. i do occasionally up my dose for a few days if i&#039;m feeling down, this seems to stop a depressive episode from developing. after a few days i drop the dose down again and seem to go on as before. overall i feel normal and would be lost without this medicine."