"my depression was primarily characterized by hopelessness and lack of motivation, and within weeks of starting wellbutrin, i experienced dramatic changes in my mood and mindset.  i often forget that i even take wellbutrin because it has given me no side effects and has only made me feel the way i was always supposed to feel.  this drug is definitely worth a try; even if it doesn&#039;t work so effectively for everyone, the potential for a negative experience is very low compared to that of other antidepressants."