"i was diagnosed with bipolar disorder when i was 17 i&#039;m  now 19. i was on seroquel for about six months and it did improve my episodes to be a lot less frequent. it was a god send in that area, but the side effects were horrible. i gained about 55lbs in five months. i went from a size 4 to a size 12 in a very short amount of time, i became very depressed, i spoke with my doctor and stopped taking it, and i%u2019m doing fine. i have not had any episodes since june 2009 and the weight is coming off very easy. i just exercise three times a week. overall i rate this medication with a 6 just because of the side effects."