"i&#039;ve suffered from severe panic disorder since i was 10.  i am 45 now. i was on 200mg of zoloft for 18 years. it took away my anxiety, but also took away any motivation. i was a zombie for all of those years and slept all the time. my new dr. suggested switching to effexor. i was afraid that it wouldn&#039;t work and my panic would come back. i was so wrong. after a week on 37.5 mg, my energy was back and anxiety still gone. i&#039;m on 75mg. i can&#039;t believe i stayed on zoloft so long! i can think and do things again! i don&#039;t sleep all the time. everyone reacts differently. if this med doesn&#039;t work for you, i&#039;m sure there is one that will. wish i would&#039;ve switched sooner. no side effects at all!"