"i&#039;ve been on buspar for two years. the drug does not &#039;kick in&#039; quickly, but once it does start working, one notices a nice, quiet calm. (it started working for me after ~ 30 days. )it&#039;s nothing like the benzodiazepines (thank goodness) and does not make me feel like a zombie with memory problems like clonazepam (klonopin) or valium, etc. i use this in conjunction with cymbalta and this combination helps me with both anxiety and depression. the only side effect i notice is that i might sweat a bit more. it is non-addictive, but as with any drug used long-term, one become physically dependent upon buspar and one should follow a withdrawal schedule formulated by your pcp."