"i took the depo shot twice, one shot every 3 months, right after highschool. while i did not get pregnant i gained 50 pounds. i had always been a tiny person. i was 100 pounds when i graduated and after that 6 months i was 150. no change in diet and i was actually more active. after i decided to get off of it i was unable to lose the weight and i didn&#039;t get my period for 9 months and was not abe to get pregnant for a year and 9 months, which actually was failed (blighted ovum) and i finally am pregnant 2 and a half years later. all from 2 shots. my whole life i had very regular light periods.  after the shot they were random and fluctuated in flow from heavy to only spotting.  i would never recommend this birth control."