"i started taking the doxcy (100 mg) once a day for my acne.  i am 29 years old female that had never had acne in my teens until now at this age.  okay so i began with this pill and for me it got worse before it got better. i took this for a month and a week and i did see improvement till like my 4th week of using it. so then my derm prescribed the same doxcy  (100 mg) but now twice a day which is much better along with tretinoin cream 0.05% every night. this has helped me so much. one big tip that i can give you guys is not to stress about the acne i know it&#039;s hard but stressing will only make it worse. just think that one day it will go away.  now it&#039;s been  25 days with the new prescribed doxcy and finally no more acne."