"have dealt with gad anxiety most my life. started taking effexor for a major depression episode.  doctor stared me slow.  33 mg for 4 weeks, then 75 mg for 3 weeks, then 108 mg for 2 weeks and finally 150 mg.  been on 150 mg about 6 months, some side effects along the way.  just basically feeling &quot;weird&quot; was the worst side effect.  wanted to quit many times along the way, but stuck with it.  it doesn&#039;t work overnight. 
sexual side effect is hard to have a orgasm, but i can deal that if i feel better.  depression
is no fun.  good luck all.  tomorrow&#039;s always can be a better day.  god bless."