"i am 28 years old and started breaking out severely a few years back. i tried every otc acne medication and cleanser. i finally went to the dermatologist and was diagnosed with hormonal acne. i was prescribed ocella and tretinoin cream. i&#039;ve been using both since april 2015, however i noticed that as long as i take my ocella everyday i do not need the tretinoin cream so i haven&#039;t used it in a couple months. my skin is such much better and i have to remember to take my pill every day because the hormones wear off after 24 hours and i&#039;ll break out if i miss it two days in a row. otherwise this medication has been heaven sent. "