"the first time i took wellbutrin i was in the hospital for major depression, suicidal ideation and a nervous breakdown. after trying the typical zoloft, paxil and others the drs. were running out of options. a new dr. on staff gave me wellbrutin (i dont remember the dose) and i instantly was transported to a state i can only describe as ecstacy. unfortunately this lasted only one day probably because of my &quot;virgin&quot; brain. but staying on this med. for two years helped me recover my life. i am so grateful. this was 15 years ago and although i still suffer from major depressive disorder i have been able to get a master&#039;s degree and a new career."