"28 woman 140 lbs--150mg xl taken once in the morning. before this i was getting near suicidal, couldn&#039;t get out of bed and hated myself for that. sought a therapist who recommended besides therapy i should take something like wellbutrin. my psych was irritated b/c i previously told her i didn&#039;t want celexa (it never did anything even after months) but agreed to prescribe wellbutrin. after a day or two when it kicked in, it was like night and day. like a cloud had been lifted and i could see again, get out bed again. don&#039;t get me wrong, i&#039;m still sad about the state of the world and my life. but it&#039;s not crippling anymore; i can &quot;get over it.&quot; i&#039;m glad to keep experiencing. it seemed better year 1 than 2 but that might be the relief/other factors."