"i suffer from mild depression and back pain associated with scoliosis. i hoped cymbalta could help. it did not help me. initially (first few days), it was positive mentally, despite side effects: headache, nausea, then bad anxiety. as i took it more, i just started to feel not like myself, lethargic and weak. i almost felt too calm and didn&#039;t care. i can see how this might be helpful to those that are severely depressed. i am not. i&#039;m sharing my experience because if you only suffer from minor blues, i would not recommend a strong anti-depressant. i told my doctor it was minor, yet he prescribed me 60 mg immediately. i gave it a month and felt worse each day."