"i have posted here before after just starting pristiq.  i&#039;ve now been on 50 mg of this drug for depression and anxiety disorder for 6 months and i honestly think this medicine saved my life.  i was stuck in such a deep dark depression with severe anxiety attacks.  i couldn&#039;t function like a normal person. everything seemed so hard.  i couldn&#039;t sleep or eat.  i started pristiq and it took about 2 months for me to fully feel the positive effects, however i did notice a big change just 2 weeks into taking it.  the only side effect i had early on was insomina and night sweats, but those are no longer an issue.  i do notice though that if i miss a pill for more than one day, i start to feel depressed again. overall, the best medicine i&#039;ve taken."