"i have been on this medicine, changing from 30 mg ms contin twice a day and 60 mg at night, to 60 mg ms contin 3 times a day, going on two weeks now. i am also still taking my 15 mg oxycodone immediate release for breakthrough pain, taking that 5 times a day as well. all i can say is &quot;yay&quot; for my doctor. i have my life back. i am working two job and also i am able to ride my bicycle now. if not for my pain management doctor treating my pain with these medicines, i wouldn&#039;t be able to do any of this. the 60 mg ms contin works hand in hand with the oxycodone. i went from total 100 per cent days of severe pain and extreme knee cramps and locking up, to almost no pain days, totally pain free with this medicine. what a relief."