"first day on adipex...i weigh in at 245 pound&#039;s, i&#039;m 33 and 5&#039;7. i tried adipex 2 yrs ago when i was at my heaviest which was 286. i lost a ton of weight, i went down to 215 and was super happy. i went through a lot in my life and became depressed and gained 1/2 of the weight back. i can tell you if you want to loose the weight you have to diet and exercise,  i was going to the gym 3 to 5 times a week 2 yrs ago before the major stuff happened in my life. i am starting my new journey today and couldn&#039;t be happier about it. my doctor put me on adipex-p and topiramate to help with my weight loss program. i don&#039;t start the topiramate until next week so i&#039;ll let you guys know how both of them work."