"i loved the depo shot. i was on it for just under two years,  and had no problems.  i used this as my only form of protection since i am in a committed relationship.  my only slight issue is that i gained alot of weight (about 70 pounds). my doctor believes this is due to the stress of a new job,  a promotion,  and some life changes, not the depo.  i quit the shot in order to confirm, it&#039;s been almost three months and i&#039;m still gaining weight,  so maybe the doctor was right. i had no other side affects,  and no period,  from the day i started. i haven&#039;t gotten my period back in the last three months. i plan to go back on the shot very soon.  it&#039;s the most convenient by far,  and despite the horror stories,  i&#039;ve never had a problem."