"bipolar 2 cyclic .started with serequil, lamictal and vyvanse. serequil worked but horrible side effects: urine retention. daily ha, all day long nausea, weight gain 22#. despite watching diet and daily swim.  started  latuda took 40mg  at dinner (8pm) for 4 week. what a great mood stabilizer for me but still having periodic days of mania and depression. inc to 80 mg. doing great. within 3 weeks of starting latuda lost 20 lbs ( almost like my metabolism kicked into overdrive) after being on serequil.  side effects:  my stomach super sensitive so of course nausea.  i must take 1 hr after dinner, letting food digest, no alcohol. otherwise vomiting within 2 hrs after taking. i take rx haldol 0.5mg bid and zofran odt for breakthrough nausea"