"since i was young i have suffered of cystic acne.  i think is hormonal because sometimes my face is clear and sometimes is not. now that i am 35 i decided to go with zenatane because my dermatologist recommended it. i am on 30 mg twice a day. i have been using this for one month now i am on my second month and the side effects are horrible. dry lips, eyes, sleepiness, and the worst joint and muscular pain on my upper middle back, neck, chest, knees, hands , and hips. i am not exaggerating i feel like an old lady of how stiff i feel especially in the mornings. i also have some stomach discomfort and mild heart burn. i don&#039;t want to continue but my skin just in one month has improved a great deal."