"i have struggled since the age 15 with acne, i am now 35 and decided to go to the dermatologist again convinced to start using accutane. my doctor put me on 150mg of doryx along with epiduo at night. i am on day 15 and all of my existing cysts have since gone and had no new breakouts. it is a big pill and have to take it on an empty stomach so some will have cramping, mine are not bad."