"i was on tri-sprintec for 6 months and didn&#039;t have any problems with the first 4 months, no headaches, weight gain, or cramps. a little nausea for about 30 minutes after taking the pill, periods were lighter and a bit longer. after the 4th pack i started to have spotting and break through bleeding, eventually bleeding for 3 weeks at a time. i also started to have severe mood swings, that got so bad they affected my work and i had to schedule an appointment with my gc. when talking to my gc this can be normal with some patients so i was switched to a lower dose pill, don&#039;t know how that works yet."