"i&#039;ve been taking 120mg of cymbalta for 6 months now &amp; have found the benefits to be: decreased anxiety; increased social confidence; and 10kg (22.2 pounds) weight loss!! the negatives have been: irregular insomnia; slightly manic personality when really comfortable in my social surroundings; dry mouth; mild occasional nausea &amp; that&#039;s about it. i&#039;m under the watchful eye of a great psychiatrist &amp; think cymbalta is much better than prozac &amp; zoloft which i&#039;ve been on for 5 years prior (at alternate times). also, i strongly recommend reducing your alcohol intake - cymbalta increases side effects &amp; makes you feel embarrassingly drunk &amp; tired much earlier than others. good luck."