"i have been on sertraline for 4 weeks now. i started on 6 mg...yes i cut up the pills into 1/8! after 1 day of nausea i felt much better. after 2 weeks i moved up to 12.5 mg. still feeling great. i wish i had done this years ago. while my main problem is anxiety, on reflection i have  been depressed for years. hope the very low dose continues to work. life is just so much better, i am not constrained by wanting to go home all the time and most amazing anxiety over ridiculous things like waiting in line, etc."