"i just began the fentanyl 25mcg patch 2 days ago.  so far, so good.  i&#039;m pain free for the first time since cervical spine surgery in april 09.  i put the first patch on around supper time and noticed a reduction in pain within a couple hours.  when i got up yesterday morning, i was pain free.  this medicine is incredible.  the doctor gave me norco 10-325 for any break through pain but so far, i haven&#039;t had any."