"great pain medication! my doctor suggested it after taking 8-10 vicodin 10&#039;s per day.  i started with 20mg/12 hours, then graduated to 60mgs, after about 8 months. i did not like the &quot;disconnected&quot; feeling assoc. w/med increase; at that time, it was a small price to pay for pain relief. i currently take opana in im and ex., i am having quite favorable results, and when compared to kadian, they seem quite similar, except op processes thru kidney. (good)"