"i started this medicine about 6 or 7 months ago. i was irritated, crying,and worst of all a very angry woman. i wanted nothing to do with anyone, even left my husband. after that i went to my doctor and told her what was going on and after trying zoloft then wellbutrin, i ended up on effexor 3 x 37.5 pills a day and now i love everyone, feel like my &quot;old&quot; self again (came back to my husband). but, now i am dealing with extreme exhaustion that makes it very hard to get out of bed so now waiting on blood work, possibly sleep study, or changing med."