"i have had problems with acne all my life. i tried everything from creams, gels, pills and even accutane.  accutane was extremely harsh and my acne was back within 3 months. i finally was prescribed doryx along with acanya in the morning and epiduo at night. please be patient as this will make you break out really bad at first but i promise you after 2 months you will see the results. what&#039;s great too is you can adjust the dosage once your face clears up so you don&#039;t have to take 150mg all the time. my face is all cleared up now and i only take it the week of my period to prevent breakouts."