"i suffered from inherited depression (chemical imbalance). my family doctor put me and my mother on it at the same time. we both were nauseous and had headaches for the first 2 weeks, the subsided. then we went up a dose after a month to 100 mg and had the same side affects again but then went away. now we are both happy-go-lucky. zoloft made me normal again. which i had forgotten what normal was years ago. saved my marriage and my life as well. i recommend taking it at night though. "