"i tried zoloft for depression and it made me hyper.  paxil works.  i have used it two times during my life when i was depressed and self-help was not working.  it worked great for depression and i didn&#039;t have many side effects except that i cannot achieve orgasm while taking this medication.  nada.  i have a wonderful husband and i am used to a good sex life.  paxil kills it.  as soon as i&#039;m off the drug for a week, everything comes back.  i hate losing sex but i hate being depressed more.  in the end, that is the choice for me."