"depo is great! i recommend it to everyone that i know. i have been on depo for about 2/3 years now, and frankly, i don&#039;t fault depo for the &quot;side effects&quot; i have experienced. yes, i have gained some weight. but i also eat a lot of carbs and don&#039;t exercise nearly as much as i used to. so you can&#039;t blame depo for that. also, my doctor made it quite clear to me that depo could affect my bone density, so i take a chewable calcium supplement every day, and so far my bones are in great shape. and let&#039;s talk about the number one life changer- no period! i used to have awful cramps and heavy bleeding, but now i literally have no period whatsoever. occasional spotting, but that&#039;s really rare and only lasts for a day. do yourself a favor and try depo"