"i have been on cymbalta for at least 4-5 years.  i took it with lamactal also as it did not seem to help or put the anxiety/depression.  i now am doing acupuncture and going off both drugs.  horrible!!!!!!!!  i tried to tell my doctors that i still felt crumby on cymbalta but they just upped my dosage.  i think there are other ways to deal with anxiety and depression.  at the very least you should find out if a certain drug works well with you by checking it out with a pharmacologist, so you can be matched.  good luck to all who are suffering, it is not much fun."