"i&#039;ve only been using nucynta for a couple of days, but so far it is working very well for me with very minimal side effects.  i have chronic sciatica and have been on and off of low does hydrocodone for a couple of years now.  i&#039;ve been taking 50mg of nucynta 2-3 times a day.  this seems to work almost as well on the pain and just seems easier on my body.  it does make me a bit &quot;loopy&quot; and a little groggy, but no more than the hydrocodone.  i also have noticed that i&#039;m not as hungry, which is not necessarily a bad thing!  i will be interested to see how it works over time and whether it continues to work well over a period of time."