"i&#039;m a 33/f w/ cystic acne my entire life. i been using epiduo forte and aczone for over 4 weeks now. i started using the aczone daily in the am and epiduo every other night along with doxy. face started clearing  w/o any dryness. then week 2, i began using the epiduo every night and within 2 days, my entire face broke out. but, this was expected and i knew purging might occur. however, the pimples did not last long. only about 2 days or so and came to a head quickly. i&#039;m pretty confident the pimples dried up quickly because of aczone. face got pretty dry though. so now, i use an daily exfoliant, hydrating serum (put on before meds to combat dryness/irritation), meds and cerave (am/pm) lotion. works great!! just have to be patient!"