"i started taking qysmia in early feb 2015.  i am 5&#039; 7&quot; and weighed in at 283.  i spoke to my dr with factors of pcos, obesity, diabetes on both sides, pre-diabetic, high cholesterol, and other concerns. i eat fairly healthy, have tried a number of things to lose weight over the years.  i lost 18 lbs six years ago when i felt like i was doing everything right.  went to the gym, worked out at least 2 hours with cardio, swimming and/weighta over the  course of 6 months. only lost 18 lbs.  frustrating!!! so, i got brave enough and talked to my doctor.   with a combination of a reduced calorie diet and cutting back on carbs while boosting the low fat proteins, i have lost over 50 lbs in 3 months with no gym membership.  i do stay active though."