"i&#039;m 27. i have 2 kids under 3 years old. i got pregnant using the pill so i decided to try the nexplanon since i wouldn&#039;t have to worry about taking it. it had been effective as far as not getting pregnant but it has had horrible side effects for me. 1. mood swings (i&#039;m clinically bipolar and on mood stabilising medicine for that) it has highly agitated my moods. 2. panic attacks/ anxiety. i&#039;ve never had them until i had this put in. 3. headaches. 4. no sex drive. 5. extreme fatigue. i literally had no motivation to do anything no matter how much rest i got. 6. continuous spotting for 6 months. i though that these symptoms would eventually wear off as my body got used to he meds. not the case for me. had it removed today."