"i&#039;ve had cystic acne since the beginning of college. i&#039;ve been on orthotricyclen lo, tri-previfem (generic orthotricyclen), beyaz, and now i&#039;m currently on tri-sprintec. the orthotricyclen lo helped a little with my acne, but i still had a lot of breakouts. i was on it for around a year. i then switched to tri-previfem, which worked great for me (no side effects whatsoever) it helped regulate my period really well too. i was on it for around 2 and a half years and my acne started coming back. a different doctor switched me over to beyaz since she said my body was used to the tri-previfem. i was on beyaz for 7 months, but noticed many problems such as weight gain (i gained 8 lbs) and moodiness. i switched to tri-sprintec and works great."