"i&#039;ve been using antibiotics for acne for years now. i started off with minocycline for 4 years until recently i switched over to doxycycline. when i switched over to doxycycline, my face cleared up and i felt so much confidence. there were two types i used. i first used doxycycline monohydrate for a year and it stopped working for my face. then i switch over to doxycycline hyclate. hyclate is stronger if you have really bad acne, but i prefer you talk to your doctor about it first."