"the side effects got worse the longer i was on nexplanon. at first, the side effects were minimal, but by the third month i was getting periods that lasted 10  days and was spotting the rest of the month. it made me extremely emotional and depressed, which became noticeably worse during my periods. also, i had never had any acne during my adolescence years, but ever since i got on nexplanon, my entire face is covered in pimples. like said before, the acne wasn&#039;t as bad in the first few months, but got increasingly worse."