"i have suffered with depression for 4 years and have tried so many drugs that i have lost count. i finally found a combination of drugs that were working, but not completely. my np then added provigil and my depression resolved.  i am able to get a lot done without feeling tired all of the time. however, i was on 200 mg and only had mild benefits. my np increased the dose to 400 mg and it has helped tremendously. it has given me more hope that i have had in years."