"i&#039;ve been on the depo shot for about 9 months. i decided along with my doctor to get the shot because i have what is called bacterial vaginosis, cysts on my ovaries and also constant yeast infections. it has seemed to help with all of the above reasons of why i initially started the shot. on the shot i have experienced horrific migraines, nausea, extreme mood swing, severe depression and high levels of anxiety. i also spot monthly and for the first two months i bled heavily. i am actually going back to the doctor to switch to either a different birth control or to completely get off of bc. i hope this helps ya&#039;ll!"