"i&#039;ve had depression for years (runs in family). i was on prozac (didn&#039;t do much) then switched to zoloft. after a while on zoloft i noticed that i felt like a zombie, almost devoid of emotion but prone to rage at times. i switched to lexapro and it was as if a light had been turned on. wow! i had energy and positive thoughts again plus motivation, which had been completely lacking on zoloft and prozac. i did have headaches but started taking the pill at night which worked. i would stay on lexapro and give it a 10 rating, however lately i&#039;ve felt quite jumpy and nervous. sometimes i feel a little anxious but not bad. i&#039;m going to now try celexa, which is supposed to be much like lexapro but with less anxiety."