"23 year old male.  ive had mild-moderate acne on/off since high school.  tried everything else so decided to give accutane a shot.  for me, i took 40mg the first month and went up to 60mg for the remaining 5 months for a total of 6 months.  months 1-4, acne got better gradually with breakouts here or there.  months 5 and 6 my skin was completely clear.  dryness was the only side effect i experienced. i would recommend this drug.  if you are frightened by the negative effects some people have had, i would say remain on a lower dose and be patient. the bad side effects supposedly increase at higher dosages.   another note: i weigh 160 lbs and the target mg for me was 72mg a day. i did less and still saw results"