"i have been on lithium for about 1.5 months, along with lamotrigine.  as soon as one week, i could tell a difference in myself.  i was finally starting to feel like my &quot;normal&quot; self.  at the time of starting these medications, i was easily agitated, would get angry at everyone over simple things.  i found i was grinding my teeth a lot, trying to cope with my feelings.  i was also becoming reclusive, since everything bothered me, i tried to avoid people and things that bothered me, so i would &quot;hide&quot; in my bedroom, and then the depression set in.  so far, these two medications have helped wonderfully, and have changed my life!"