"i had acne breakout since i was 13 and i started the medicine at the age or 23. in the six month process i had 10 mg to 50 mg intake which gradually was increased per month by my dermatologist...i would advise to take the medicine in guidelines of a doctor as he will help to minimize the side effects of the drug also will fix the maximum dose depending on the condition of the skin....i myself don&#039;t have any side effects at all only dry lips...but a good lip balm helped me through"