"seroquel has worked wonders for me.  i have been diagnosed with bipolar 2, and after 7 months on seroquel, i feel like a whole new person.  i had been severely depressed and was self harming before getting on seroquel, and now i have never been so happy before!  the only problem is the weight gain - i have gained about 20 pounds since i started taking this medicine.  but this side effect is worth it to have my depression and anxiety gone!"