"the first 3 times i had this shot, i bled in the 2 weeks leading up to when i was due, but otherwise had no periods. however, i switched to a new doctor who recommended i should be getting the shot every 12 weeks, as opposed to 3 months and since doing that, i haven&#039;t bled once and it&#039;s been over 2 years. i do notice the area of the shot is quite sore for 2 - 3 days after, but it&#039;s nothing i can&#039;t handle. my biggest complaint would be the effect this has had on my skin. i had reasonably clear skin before taking this shot and i would describe it as normal - combination. it is now super oily and i have moderate acne, which flares up badly every time i get the shot. overall, i am very happy with depo, it is cheap and no need for daily pills!"