"i first tried the generic for topamax and i just felt depressed. i&#039;ve been on lexpro also for about 2 years. when i got prescribed seroquel i was nervous about the &quot;tired&quot; side effect, but my pdoc said as long as i take it before bed i should be okay and might feel some fatigue. first week, i was extremely tired when waking up. i would sleep at least 10 hours and it was still difficult for me to wake up. i slept the whole night and fell asleep great, but wow it was very difficult to get out of bed in the morning. i was told no not up my dose the 2nd week. after 2 full weeks i felt like a zombie. yay for being calm, but i was too calm. no motivation to work, college homework, and i started feeling sad and crying for no reason. not for me."