"i used to have intense menstrual pains. i started taking sprintec in 2012 so i&#039;ve been on it for almost 5 years. i did not have an adverse reaction to it. the menstrual pains are almost completely gone. i notice when i do not get much exercise that month i have minor cramps. my periods (usually spotting or light period) start on wednesday and usually is gone by saturday. i&#039;ve downgraded to panty-liners. i always try to take my pills at 10:30 every night. occasionally, i would be an hour or two late and after i got into the habit of taking the pill everyday i stopped taking the white sugar pills. acne actually cleared up, no weight gain, or depression."