"i&#039;ve been suffering from major depression disorder, ptsd, and anxiety for a while now, i take 225mg of effexor which is supposed to help with anxiety, in my case it doesn&#039;t. it does help with the depression. my anxiety it terrible and leaves me up for almost 3 days at a time. i&#039;m on 0.5mg of klonopin 3 times and day (does not make me tired) so my dr recently prescribed me quetiapine 100mg at night to sleep and that was way too much, i&#039;d sleep for like 12-13 hours a night , now i take 25mg and it works ok. only side effect is that if i don&#039;t fall asleep fast enough after taking it, it causes restless leg syndrome which is another nightmare in itself. nothing else seems to work so i&#039;ll stick with it for now."