"while tri-sprintec is effective at preventing an unwanted pregnancy it has the worst side effects i have ever experienced on a birth control pill ever. i&#039;ve only been on it for a little over a week and i have to stop using it. it has given me excruciating stomach aches, nausea, fatigue, migraines, and worst of all it is aggravating my anxiety levels. i feel like i&#039;m on the verge of having a major panic attack since i started taking this awful pill. not only is my anxiety getting out of control but i also feel depressed and uninterested in everything. all i want to do is sleep. i wish my stupid insurance covered ortho tri-cylcen lo, that has been the best pill so far. i don&#039;t recomment tri-sprintec to anyone."