"i was taking the 60mg op&#039;s for a little over a year, (i was on the regular oxycodone before the change)--they were making me extremely nauseous, at times violent vomiting and dry heaving.  it started with the nausea immediately and then it seemed like every 3 months i would have a bout of nausea, vomiting and dry heaving that would last for days.  i was in the hospital 4 times this past year. i am taking opana now. i have been on it almost a month and guess what?!!  no more of the daily nausea and worse again.  doing well on opana. wish i could have gotten it sooner.  my insurance would not pay for it at first, but now they do! good luck everyone."