"seriously messes with my emotions so much. i already live with anxiety &amp; depression and the depo just makes it so much more worse! i hate it. i get pissed off at things i shouldn&#039;t get pissed off at! i have all the period symptoms (cramps, emotions out of whack, retaining water and horrible craving for sweets) and irregular bleeding. i&#039;m gaining so much weight and i&#039;m not even eating unhealthy, i have a strict diet and workout and i stil gain about a pound or 2 every 2 weeks. do not recommend the depo to anyone. this sucks."