"i switched from yaz to ortho tri cyclen lo and i&#039;ve been on it for almost three years. i liked it for the most part, my period was very predictable every month with minor pain-no mood swings or weight gain. i do get yeast infections more often than i ever have before though and i did get breast tenderness from time to time. i have now been off it for almost three weeks because my hands and feet have been swelling up. i&#039;ve been tested for everything and so far all my blood work has come back negative so the only culprit at this moment is the ortho tri-cyclen lo. "