"i am an r.n. and diagnosed 20 plus years ago with clinical depression, i have also been on just about every antidepressant.  a week ago i requested help from my physician due to the increasing depression and lack of help from cymbalta he prescribed brintellix.  i switched immediately and some of the symptoms are withdrawal from the cymbalta.  the &quot; reverberations&quot; in my head are distinctly withdrawal symptoms.  my headaches appear to be from decreased sodium which is a brintellix side effect and for me are eliminated by drinking gatorade which is high in sodium.  the nausea is a toss up and eased with ginger ale and carbs.  the itching responds to 1 benadryl.  4 weeks is the norm for side effects to subside.  identical to original prozac."