"i have been struggling to find a medication for my simple depression for about a year in a half now, basically tried all ssri&#039;s and s couple of others, i am now on 40 mg of prozac ( which i feel like i don&#039;t need) and 150 mg of regular seroquel before bed, the xr made me really tired and moody, plus the expense was outrageous, but trying the regular i finally feel myself again, although its my first day taking it i feel balanced out and basically normal again. ps if your struggling out their keep fighting! god put the hardest problems on us for a reason!"