"i am 49 and have bipolar ii. been on seroquel 400 mg for one year. initially very drowsy, restless legs, dry mouth and blocked nose, most side effects lifted after 3 months. this medicine controlled my racing thoughts, helped me concentrate (i thought i had add). ironically, despite the drowsiness it lifted my extreme exhaustion (i used to have weekly vitamin b injections because i was so tired). i no longer feel drowsy, managed not to gain weight with the help of a dietitian and an exercise program. i do get very hungry but refuse to give in to the hunger. i also take wellburtin and zoloft to help the depression, tearfulness and agitation. i would recommend seroquel to bipolar patients."