"this medicine along with a 5htp2 inhibitor helped lift depression in 2 months. i took prozac after that for about 8 years with some break in between. when in depression a higher dose helps, for maintenance low dose was enough. if you don&#039;t see effects after 6-8 weeks at the high dose level, adding a medicine with a different action adding lithium at a small dose may help. this was the case for me. brain is interesting and unique, but it is able to repair itself which is a great thing. it will get back to normal or even better with the right medicine. don&#039;t underestimate the effect of adding exercise, fish oils, sunlight, social support, yoga and other healthy habits. some of us have high maintenance brains, but it is totally worth it!"