"iv been on depo for 3 years , and i can say its better than other birth controls you deffanitly won&#039;t get pregnant its probly hard to conceive even after you stop getting it. i have gained about 35 lbs mostly always hungry. i get acne on an off an have mood swings . i&#039;m thinking about getting off of it cus i heard it decreases bone mass an putting that in your body for long time can&#039;t be healthy"