"i felt a change in my moods from lamictal almost immediately. i haven&#039;t felt that great in years, but i developed a rash in 1-2 weeks of taking it. it started as itchy hands and feet and then i itched everywhere.  i did not have a severe or life threatening stevens-johnson syndrome. i did drink alcohol on this medicine and it made me get drunk really fast and i would have very bad hangovers. i had to discontinue after 1 1/2 months because of the rash. two of my friends take this and never had rashes and they also agree it is the best medicine they have taken for bipolar."