"i have bipolar i mixed episodes, i&#039;ve been on a number of medications in the past, but lithium stands out as one of the worst in my case. i lived in a fog but also had some of the worst stomach issues as well. i gained quite a bit of weight too but the worst was the severe acne i got from the drug. i never had acne like this in my life since than or before, so i know it was the medicine. it was painful, it felt like second degree burns, i went to see my doctor and all that smug @$$ said was &quot;that&#039;s one of the side effects unfortunately&quot;.  i don&#039;t mean to sound vain but a lot of self worth comes from the outside as well as the inside and while that shouldn&#039;t be the case it&#039;s a fact for me. be informed, not all drugs work for everyone."