"been on/off topamax since i was 15, i&#039;m now 21. first time i took topamax at 15, i went frm 235lbs to 114lbs. over time i got used to it &amp; couldn&#039;t find something to help w/my binge eating disorder. i gained all the weight i lost &amp; more over a 5yr period of trying to lose it/find the right meds to help. 2012 17 y/o tried topamax &amp; had bad anxiety so that didn&#039;t last long. 2015 20 y/o i weighed 248lbs, the biggest i&#039;ve been. was on phentermine (diet pill, 37.5mg) for a few months but was starting to get used to it. decided to try topamax again (50mg 2x a day) along w/vyvanse (adhd/binge eating, 70mg) &amp; lexapro (depression, 20mg). currently 160lbs. always adjusting my meds though, i seem to get used to them quickly."