"if you cannot tolerate topamax/trokendi (topamirate), please consider zonegran (zonisamide). it is in the same class of drug as topamax, and does many of the same things. its labeled use is an anti-convulsant, but the psychiatric and pain management clinic i go to uses it off-label for a number of uses, such as: weight loss, mood stabilization, migraine prevention, mild pain reduction properties. i took zonegran successfully at 200 mg for 5 years and did not experience tingling, numbness, dry mouth or flat-tasting carbonated beverages. memory/recall did degrade unacceptably for me above 200 mg, but therapeutic dose is considered 300 mg."