"i was taking 400mg daily for chronic migraines, depression, and weight loss. it&#039;s very important to build up slowly otherwise the side effects can be extreme. i lost around maybe 50lbs while on it. when i got up to 300 - 400mg i started to have memory problems and sleep issues. after a while i felt like it had stopped working and dropped it, but that could have been from me forgetting to take it (memory issues remember). it takes a few weeks to a few months for the side   effects to fully wear off. i started at 235 or 245, and went down to 185. i&#039;m now back up to 200. i haven&#039;t exercised in years, and i didn&#039;t change my diet (i probably don&#039;t eat as healthy as i should)."