"previous med lexapro quit working after several years. cymbalta seemed to work for the 1st week but i think it may have been placebo effect, after about a week my body started hurting and feeling hot from the inside especially my legs below my knees. after about 3 weeks stiff neck, hot flashes, restlessness, anxiety, headaches. 4 weeks all these plus talking in sleep, joint pain, body aches, stiff feeling, trouble focusing and i asked to be taken off it. i was only at 30mg."