"it&#039;s an okay medicine for depression, but i&#039;ve had times where i&#039;d miss one day of cymbalta and immediately feel withdrawal symptoms (brain zaps, nausea, headache, etc...) the only other medicine i&#039;ve ever had this happen with is effexor. i hate that i have to make sure that i have to take this at the right time of day, because even being late by like 6 hours, i feel the withdrawal symptoms kicking in."