"after a diagnosis of stage iiia breast cancer, 2 separate modified radical surgeries with lymph node removal and chemotherapy, i was then put on arimidex.  had major joint pain, body aching, nauseous and anxiety, to name a few.  i tried nsaids and many narcotic medications without success.  eventually, i was put on avinza three years ago.  finally relief!  i have no side effects from avinza.  i take a capsule every 12 hours.  the dosage has been varied but little else is required for breakthrough.  i don&#039;t know what is different about this narcotic but thankfully, it works for me."