"i started taking bupropion about a month ago to treat chronic mild depression. my depression was generally manageable but i had periods when it became debilitating, keeping me from performing daily activities, etc. with bupropion, so far i feel great. it&#039;s amazing to see the person i am without the constant weight of depression bearing down on me. it feels like i&#039;ve gone from dredging through deep thick mud to running free through thin air. the only negative side effect i&#039;ve noticed is dry mouth which for me is nothing in light of the positive effects. i feel more energetic, motivated, and capable. i haven&#039;t seen any effect on my weight or appetite, no change in libido, and no jittery or aggressive feelings."