"i&#039;ve been on pain meds for 30  years. changed to opana er 20 x 2. this made a large difference but still had breakthrough pain so dr added opana ir 10mg. these i break up into thirds, halves, or quarters as needed.  i couldn&#039;t use norco because of breathing problems. this dosage isn&#039;t perfect but i&#039;m no longer whining every time i get in or out of the car. 2 major surgeries coming over the summer. i hope opana continues to work."