"i have been off and on buspar for a little over a year now for severe uncontrollable anxiety but i have to take a high dose for it to work. i just take it as needed. i take 40mg at night. that&#039;s when my anxiety seems to bother me the most. if my anxiety is bothering me really bad and i don&#039;t take it then i am always up all night long and sometimes 2 days straight. overall i would recommend this medicine!"