"i have been on zoloft for about a month now and went from taking 25mg a day to 150mg a day.  i was mildy depressed and had no motivation to enjoy life.  i have to admit that i have felt better inside but still lack motivation.  the side effects are pretty tough, i can&#039;t stop yawning all day long and my sex drive is non-existant. also having great difficulty in ejaculating. i think the doctor is moving me over to lexapro."