"i am on my 5th week. started at 209 lbs and am down to 196. i am also following a medical weight loss program, (that i try hard to stick to) track my food in myfitnesspal and take a hot yoga class at least two days a week.  mild nausea during the step-up period, no other side effects.  i am normally an anxious person and this does not increase  my anxiety at all. i also suffer from migraines and have seen no increase in those either. i feel great.  i find that taking the evening dose around 4-5pm helps with overeating at dinner and evening.  this medicine is helping me stick to a &quot;diet&quot; program for the first time in my entire life.  i even had lap-band surgery six years ago and didn&#039;t see these types of results. i am very happy with it."