"i weighed 377 in may of 2014 when i started taking the the combination of phentermine and topomax.  eleven months later, i have lost 78 pounds and i&#039;m continuing to loose weight every week.  the drugs work better than anything i have ever tried before.  i eat a small breakfast, no desire for lunch, and whatever i want for supper.  i do not &quot;snack&quot; at all, nor do i have a desire to. this combination of drugs may have saved my life.  side effects will go away after a few months... stick it out."