"i got my first depo shot about a week ago. i went right from the pill to the shot. this shot is ruining my life right now. i am constantly nauseas, i have chronic fatigue, and i have constant head aches. i also can&#039;t stop eating and feel hungry even after a big meal. i am praying that these side effects deminish bc it is making my social life, professional life, and personal relationships very rough."