"i took zoloft for a long time and it stopped working.  i am so glad it did.  pristiq is 100 x better.  it controls my anxiety and leaves me clear headed, i.e. not numb.  i experienced some insomnia and increased sweating during the first week but it went away.  the only side effect i experience now is constipation, which i hope will go away because i don&#039;t plan on parting from this medicine for a long time.  it&#039;s been a life saver for me and i love it."