"i&#039;ve been on this drug since the us release date, previous to that having to cross the border into mexico to buy provigil. luckily i have no insurance hiccups with nuvigil besides yearly prior authorizations. i have sleep apnea to which i&#039;ve had 5 surgeries to correct &amp; am bipolar 1. i take 2 x 250 mg. tablets daily, spaced by 5 hours--it really helps with the extreme lethargy you get from atypicals &amp; mood stabalizers, i don&#039;t think i&#039;d be able to hold a job without it. this is not some miracle limitless drug for those who seriously need it, its a way to change your life to keep up when all your other meds just slow you down. i was on 1 dose a day &amp; it wore off within 5-6 hours, thus the second dose. $5 copay with coupon on their site."