"i have been taking isotrention for 2.5 months and i have got almost completely clear!! the main side effects i have felt with were joint pain mostly in the middle back and sometimes neck and hands but nothing ibuprofen couldn&#039;t help!&quot;. i live in a cold climate and haven&#039;t really experience an insane dryness all over just mild in certain areas the ears being the most surprising! i love this product it has worked a miracle. if you are hesitating - don&#039;t! get on this - it will change your life!! the only reason i gave this is a 9 is i still have a few small scars so i think i will have to use something else for that anyway good luck to all!! :)"