"rexulti is a terrible medication. didn&#039;t seem to work at all and made me gain about 25 lbs. at 32 my metabolism isn&#039;t quite as quick as it once was so i&#039;m having trouble getting the weight off. only been off the medication for a couple weeks. my doctor changed me over to seroquel per my request.as long as i am not overly sedated or have weight issues seroquel is fine with me. i know many do not like it for the side effects and overall sedation. i feel like rexulti slowed down my metabolism because i cannot explain the excessive weight gain over such a short period. it&#039;s a newer drug so we do not know much about it. whatever the case, don&#039;t take the stuff. it doesn&#039;t work anyways."