"i too have been experiencing dramatic weight loss with buspar. just read the last comment and pretty much spot on. i don&#039;t get hungry anymore. i&#039;m a 5&#039;7&quot; female who weighed 175lbs. and now i&#039;m down to 120lbs. after two   months of this medicine. also i noticed i seem to be having some severe ocd thoughts while taking this medicine. in the beginning it was all smooth sailing and now it seems like it&#039;s not working. going to try another medicine."