"i&#039;ve been taking fluoxetine for at least 18 months now for severe depression. i couldn&#039;t sleep or eat even getting out of bed to open the curtains was difficult for me. my gp put me on 40mg a day and did i notice a change in myself - not only happy but motivated and hold a job down a year later. i&#039;m on 20mg now and still have my bad days. boy do i notice it if i miss a day. it was the best thing i could have done and i swear by it."