"i am 49 years old, my mother is in hospital with 2 knee replacement and i have noticed over the years i too have pain in my knees after years of then cracking as i walked upstairs. then the pain got worse so i went to the doc and he told me to try celebrex 300 mg a day and let me tell you so far no side effects and i am happy again. the wife says i am acting strange, she&#039;s never seen me so happy but its not for all. for me i wish i would have done this a lot sooner. "