"did everything right: titrated up gradually as per manufacturer&#039;s instructions. only side effect was a slight front forehead ache in the mornings. then.... wham! about 6 weeks into taking lamotrigine woke up with migraine killer headache &amp; aching joints like getting the &#039;flu. then next morning had rash all over body which became raised bumps. then bloodshot eyes. i was in bed the best part of 2 weeks.  instantly, i stopped the lamotrigine. even though my psychiatrist just told me to reduce the dose! duh! if not for the sjs reaction, i would definitely still be on this drug."