"i recently started on opana er 20 mg, every 12 hours with opana 5 mg as needed (up to two) for break through pain. opana is amazing. i have very little break through pain and it&#039;s not bad at all. i have no side effects from the opana and was taking a total of 60 mg&#039;s of norco (per 24 hours) prior to this. the best thing is no more horrible pain like when the norco was wearing off. i feel human again and can shop and do things i did before i got hurt. i would like to note that i have read a lot of things on various web sites that seem as though people are looking to get high from pain medicines as opposed to live pain free from them. after i had my surgery a year ago i had that horrible feeling of being &quot;stoned&quot; from simple hydrocodone and i hated it."