"seroquel xr definitely helped me with my moods and rapid cycling. but.... gave it away because i was forever hungry. i lost all internal compass on whether or not i required food. which is scary for me because i&#039;ve always been normal weight and relied upon internal hunger cues to direct my eating. these cues were lost on seroquel. i wanted to eat all the time! i put myself on a strict diet yet the weight still kept creeping on. in my opinion, seroquel lowers the metabolism. such that you&#039;d have to restrict your calorie intake quite seriously. i&#039;m going to try latuda instead as it&#039;s a &quot;weight neutral&quot; preparation."