"after reading so many positive reviews on this site, i decided to try lamotrigine. i found it to be the most effective long-term drug for depression and mood stability. having tried antidepressants and most mood stabilizers, this was the best drug for me. it does not make me tired or drugged up - just substantially reduces depression. reduces overall depression, si, obsessions and anxiety. slowly went to 200mg/day as i couldn&#039;t feel much difference at 100. i had to switch to the brand name as generic was giving me stomach problems. otherwise no side effects."