"i&#039;ve been suffering from anxiety for years now and was being given klonopin originally.  after 5 years of klonopin use, both my doctor and i wanted to wean me off the klonopin so my doctor put me on trintellix (vortioxetine).   i started taking trintellix about a month ago and at first everything seemed to be going fine.   i was starting to feel &quot;slightly&quot; better.   by the third week i started to get these really bad occasional headaches and get sick to my stomach every time i ate.   i heard people say take it with food, but that just made it worse.  by the fourth week the headache was a non-stop migraine and i was barely eating.  i was so irritable that the slightest thing would set me off.   i stopped taking this drug and don&#039;t recommend."