"male, age 45. first tried prozac (fluoxetine) then paxil (paroxetine) for a month, didn&#039;t help &amp; felt a little weight gain. tried lexapro (escitalopram) 10mg for 6 weeks &amp; felt a little better. increased to 20mg really helped improve my anxiety/depression &amp; no weight gain, also take daily deplin (l-methylfolate) 15 mg, same 400mg (3x daily) &amp; vitamin d3 (4000 iu)."