"i&#039;m 27 and have had cystic acne since age 11. i took accutane my soph. year of college and it worked pretty much instantly with good results and no side effects (maybe dry lips but i barely remember that). the acne came back though about 2 years later, and i took a second cycle. about 4-5 years later (now) it has come back slowly and i am considering a 3rd round. i&#039;ve used proactiv for over a year, and that was working, but has seemed to stop working and severely dry out my skin. i&#039;m nervous about the side effects with a third round, but the first 2 cycles i had no issues- so i&#039;m hoping this round will last longer!"