"i started contrave on 10/2/15. it has been 4 weeks and its working!!! i&#039;m not sure of my starting weight exactly, maybe somewhere between 220-230lbs. every scale is different so i&#039;m waiting to go back to the doctor to find my true weight loss. but so far i can tell that my stomach is flatter and my thighs are thinner. also my wedding ring fits again!!! i have been walking 30min a day for the past 2 1/2 weeks and have been watching my diet (no carbs/sugar). i&#039;m very excited and hopeful. i have gained close to 100lbs in the past 5 years due to anti depressants and mood stabilizers. so i&#039;m really hoping to get off between 75-100lbs. currently no side effects, i have taken wellbutrin in the past so that may make a difference. i would definitely recommend"