"i have been on orsythia about two weeks. my doctor prescribed it to help control my terrible pms and cramps. i am bloated constantly. it looks like i have a little baby in my belly. my pants are tight and it sucks but i am going to stick it out and hope that it will go away after a month or so. i have been sleeping terrible and i am tired all the time. my breasts are tender 24/7 and i feel a little like in a cloud....not really depressed but not excited either. i haven&#039;t had any problems so far with acne and my appetite has actually decreased. i am hoping it will all level out in a few months."