"my physician prescribed norco 35-325 after i complained of severe abdominal pain and pain in my kidneys. i started taking one tablet every 4-6 hours (sometimes less than 4 hours apart) and it didn&#039;t seem to help with the pain, it would help me sleep sometimes. i started taking two tablets, and it seems to make a noticeable difference. it doesn&#039;t take as long to start working as if i were to just take one. it lasts a while longer too. i&#039;ve tried others and it works just as well but only when i take two."