"i was on the depo shot for 2 years. with depo i gained 15 pounds over the 2 years. although this isn&#039;t much, it&#039;s a lot for a short person (i&#039;m 4&#039;11&quot;). i had heavy bleeding for a whole year on depo, then eventually i stopped getting my period (which is great because they were extremely painful). with nexplanon, i had light spotting for 3 days and haven&#039;t had a period since. also, i lost 8 pounds in the 3 months that i&#039;ve had nexplanon without changing diet or exercise after switching. my only complaint is sometimes if you put pressure on where it&#039;s implanted, you can feel it poking. i avoid my son or husband laying on my arm because of it."