"i started contrave twice.  first time was april 2016.  i had a lot going on in my life at tat time with deaths and job losses, so had some horrible affects, which i thought was from the drug so i stopped.  the next march i met with my endocrinologist again, who put me on the drug.  i told him what happened, and he said it wasn&#039;t the contrave and encouraged me to start again.  so in march 2017 i started.  i weighed 258 lbs   i won&#039;t lie, the first week was rough.  nausea, feeling out of sorts, but after reading reviews on this sight i took others advice.  i started taking dramamine with the pills.  also took my time with the pill increase.  i took 1 pill for a month, than added on 2 pills for a month, than 3.  i weened off the dramamine and am feeling fine.  i met with my endocrinologist in june, down 31 lbs.  he was ecstatic!  it was the best dr. visit of my life.  he said to keep doing what i have been. as of today - sept 11, 2017, i have been on the drug 6 months, i am down 40 lbs.  i still only take 3 pills a day as that seems to be working.  if i hit a plateau i will add the 4th.  i want to encourage you - the firs week is tough - but hang in there.  it gets better!"