"wow. where to even start. i&#039;ve been on several cocktails of antidepressants from ago 13-28. finally, my doctor prescribed methylfolate in conjuction with celexa. within 10 days, i felt more alive, motivated, energetic, and at peace then i had ever felt in my life. absolutely a miracle. if you have given up on the endless trial and error, please, please give this a chance."