"for about 30$ a bottle i was taking 100mg in the morning and 50mg at night. i weight about 100lbs. i&#039;m a teen and my acne blows. this helped to reduce how &quot;angry&quot; my acne was. however i will say this made me completely lose my appetite and if taken wrong can cause severe nausea. i did get 3rd degree burns when i was on it last summer and went off it for this summer however i might go back on it due to the fact the new topical cream i have sucks. all in all doxy was my hero but it definitely is a lot to handle."