"i was on accutane in high school, it worked for a few years, i took birth control for 8 years so that may have helped a lot with the acne too. after having my daughter i went off birth control permanently. my acne returned pretty quickly. i had moderate/severe acne on my cheeks and jawline. i saw some improvement with epiduo after about 3 weeks but its been 10 weeks and i have only a couple active zits. my skin looks good, just the old scars left and i think it&#039;s even helped minimize those. i don&#039;t really like prescription medicines in general, i prefer natural, but, this surprisingly works."