"i have suffered from clinical depression for years. i barely have enough energy to get out of bed. my house is a mess and so am i. my md put me on 75 mg of nuvigil and the effects were amazing and instant. the only side effect i had was a mild headache and sleeplessness which both went away after a few days. i am gradually getting more energy and feeling more optimistic. i can see why the caphalon is investigating this drug for treatment of depression by the fda. my biggest problem is the cost, as i have no insurance. i can&#039;t pay 1/3 of my income each month for a pill. i qualify for the patient assistance program, so will try that. otherwise i don&#039;t know what to do, as the md has only given me perhaps a month of samples."