"i went on tri-sprintec for acne and irregular periods, and it has definitely helped me regulate both. upon being prescribed this particular bc i was terrified because of all of the negative reviews, so i figured i&#039;d share my positive experience for someone who was in my position. the only noticeable side effect i&#039;ve had is a bit of chest acne (which i never had before), but as i&#039;m only on my third pack now i&#039;m hoping it will eventually clear up!"