"i was prescribed epiduo and a tablet (doxycycline), together they work great. i&#039;ve been on them for about 2 weeks and in a few days saw a difference. although another few days later it&#039;s seemed to come back. i&#039;ve suffered from acne for years and just want it gone, no regimes or counter creams work. i&#039;m not giving up on epiduo yet, i have heard great reviews. most people&#039;s acne will clear up in about a month on epiduo. my skin has peeled a bit but nothing too major, just ease onto the cream and it should be alright."