"i was taking oxycodone 15mg every 3 to 4 hours.  my doctor tried me on embeda 20mg.  it lasted about 4 hours and i still needed about 4 oxycodone tablets per day.  he upped my dose to the 50mg capsule. it works great and have not needed my breakthrough medicines at all.  i&#039;m a pharmacist and the naloxone is not released. it only comes out if you crush the pills.  it&#039;s to avoid abusers looking for a quick high.  used correctly, you will not get any naloxone (opioid antagonist). "