"i switched from effexor to lexapro after i was beginning to have suicidal thoughts. while my mood improved, my sex drive plummeted. on top of that, i gained 25lbs in a month. after completely changing my diet and exercise routine by suggestion of my doctor, i still hadn&#039;t lost any of the weight. it began to chip at what little self esteem i had, and my mood began to plummet again. it&#039;s hard to feel happy when you feel so uncomfortable with your body after a rapid weight change. i&#039;ve been switched to welbutrin sr, so we&#039;ll see how that goes."