"started pristiq 5 days ago after being on wellbutrin for years. had a series of events occur over the past six months that sent me into a deep, can&#039;t get outta bed, depression. i&#039;ve struggled with it for years. thus far i&#039;m mentally much better, but feel drugged and super sleepy. i hope this is a temporary side effect and will eventually subside. i&#039;ve noticed other posts with these same initial side affects and saw where they did eventually subside. again, i mentally feel stable, calm and actual want to interact with others instead of crawl in a hole. this is a plus for me! hoping things continue to improve. definitely worth trying!!"