"i&#039;ve dealt with depression/anxiety all of my life, or at least as early as i hit puberty. i tried zoloft and wellbutrin to their max doses, and neither were effective at all.  after dealing with unbearable constant depression i stopped seeing my psychiatrist and went to a family physician who prescribed me effexor. it&#039;s been maybe 4 months on effexor xl 75 mg/day, and i&#039;ve done a 180 degree turn around. i feel so content, so confident, rarely feel sad or bothered by little things. i started dating and met someone, and my friendships with people are stronger than ever. i finally feel like the person i should be, and more importantly i feel like an optimist. only bad thing is that withdrawal is bad &amp; it can make you nauseous. otherwise 10/10!"