"i developed severe cystic acne and nothing would work i tried creams, wash, antiobiotics and they would work but as soon as i stopped it would come back so my dermatologist decided to put me on isotetrinoin. i was very hesitant about it because the side effects. but the results were worth it. a lot of people compliment my face. i did have my lips dry all the time but tolerable because i would use aquaphor all the time to keep them moist. use sunscreen and moisturizer protect yourself from sun. i also would get really bad pain in my back specially during the first months and bad headaches too. i took this for five months and i&#039;ve been off the medication three months and my face looks great my face used to be very oily but not anymore."