"been on this for 4 months now and it has brought relief that i hadn&#039;t had in yrs. i have too many issues to name. my dose was upped this month to 7.5. i found that after abt 5 days the patch is wearing off. last month the dr changed the rx to every 5 days instead of 7 but this presented a bit of a problem w/ins filling it. since there&#039;s only 4 in a box i had to go back on day 20 to fill again (w/additional copy). still, every 5 days was better but i did still have breakthrough pain. the prob for me was that the dr changed me from 4x a day tramadol to 3x a day so i still had issues this is my 2nd week on higher dose and back to 4x day tram. the patch is good but i have rash/itch at app site and contstipation that i didn&#039;t have w/norco."