"i take a 2.5mg tablet of selegiline with breakfast and it has helped with depression and fatigue. i cut a 5 mg tablet in half.  if i miss the morning dose, i try not to take it any later than noon because it keeps me up at night.  i tried 5mg to start but i didn&#039;t feel right and had insomnia. i also take a 1 to 2 day break after taking it for 5 days straight."