"i have pain in my hands, elbows, back, knees and heels.  this medication was prescribed to me by my reumatologist, 75 mg twice a day; i have only been taking one a day.  i have been taking it for a very long time with no side effects what so ever.  i cannot tell you that i have no pain at all.  i just know that i would not be able to keep my full time job without this medication.  i also would not be able to have any quality of life.  i know in the near future i will have to take two a day, i am hoping i do as well.  :)"