"latuda is the fastest acting drug for bipolar depression i&#039;ve experienced, without side effects. i was frankly dubious about ever finding anything that would work. dr. prescribed it as an add on to lamictal, which is a slow-acting drug. i took latuda at 5 pm and the next day i was feeling noticeably better. on my 3rd day and i feel better than yesterday. if all goes well, this could be a miracle drug for me, even though it&#039;s too soon to know. it&#039;s been months after a mania episode that i&#039;ve wind-down to a depressed state, that is not severe but has been constant, where i can&#039;t even remember the path to a thought pattern that isn&#039;t guilty, hopeless, or without pleasure. i&#039;ve regained a peace of mind required to get therapeutic learned skills"