"i&#039;ve been on the depo-provrea shot for about 6 months now and i was absolutely terrified of gaining weight on it because of the multiples stories i&#039;ve heard. but, i actually lost weight, so i love it. i haven&#039;t noticed any change in mood. perhaps a slight increase in acne but hardly anything to complain about. i did have spotting for about 3 weeks in the beginning. overall, i really like it. i don&#039;t have to take a pill every day and there aren&#039;t really any noticeable side effects."