"i&#039;ve been on clonazepam for about 3-4 years and it worked for me but it put a severe damper on my libido. my doctor recommeded pristiq, so i started the weaning of the clonazepam and began pristiq. after several weeks i can say there was no effect on my anxiety, thanks to the doctor for perscribing ativan as a backup. one thing i can say for the pristiq is it seemed to correct my irritable bowel syndrome. the doc said that the ibs is probably a side affect of the anxiety and the pristiq stopped that. after reading what people posted about irregularity and the fact that my anxiety remained, i would have to attribute the results to a side effect rather than a sign of improvment. i&#039;m now taking cipralex for a week with better results."