"as mentioned in other reviews deplin is designed to augment other medications to increase their efficacy. all deplin is is l-methylfolate packaged as a prescription medication by drug manufacturers to make money on a supplement that is readily available for much less cost. if you are paying more than $30/month check out other brands it sells l-methylfolate 15 mg 30 capsules for $30. they also have 7.5 mg capsules. methylpro is not a generic deplin. methylpro is l-methylfolate. deplin is l-methylfolate. no difference. naturopaths and savvy doctors (not the medication only white coats) have been using l-methylfolate years and years before it was packaged as an expensive prescription &quot;drug&quot;. do your homework, save money and stick it to the man"