"i recommend taking as prescribed, and the bottle usually says &quot;take x amount every x hours&quot;. i think that having a steady stream of any medication is the only way to have it work. this medication&#039;s only side effect i have found is almost exactly like when one takes benadryl, and only when you are first starting out on it. i am used to it now after 3 weeks and the only effect i notice is that my hands no longer shake and my mind is at ease. much better and smoother than other meds like xanax or tramadol or klonopin, etc., etc. "