"i took pristiq for the first time today. along side of deplin and add medication. i thought it would be a good idea to take all this at night. not so much. i am wide awake and have to start getting ready for work in 2 and a half hours. i have struggled with depression and anxiety for years now. but i must say today has been one of the best days i have had in a long time. i am sure me making a change in the right direction has something to do with it but still very happy and excited.  i have had yawning already which i have experienced before on anti - depressants and i also have dry mouth. i have a pretty good cocktail going on but it had to be done."