"i&#039;ve been using aczone for close to a year now. i used to use it 2x daily but now i mostly use it a night along with differin. wow, what a difference it has made for my skin! i would recommend using a basic moisturizer as it can be slightly drying. also give the medicine some time, it took several months before i saw positive results, but my acne hasn&#039;t returned since. it won&#039;t clear everything as i still get an occasional pimple or two but the regimen i used got rid of my major acne, specifically my forehead."