"as far as acne treatments go that are effective and affordable bactrim is a god send. late 20&#039;s i started mildly breaking out. by age 30 i was getting deep painful cystic pimples. running/ exercising especially made my condition worse. bactrim ds improves acne within 24 hours.the redness and swelling is not near as noticeable. after about a week you will notice a close to clear complexion that almost glows...i had moderate acne, but i imagine that bactrim will work for ppl who have severe acne as well. it does have serious internal esp on kidneys and liver bc it is a sulfa drug so you should drink a lot of water every day with this medicince. do not drink alcohol while taking bactrim, good luck!"