"i am a long term ultram user (maybe 5 or 6 years). i have osteoarthritis. now i feel like i am taking the medicine just to get rid of the headache and runny nose that i get when i do not take it. i am trying to stop taking it and maybe switch to arthritis strength tylenol. at least i won&#039;t have a headache and a runny nose. i think it addressed my pain very well some years ago but now it&#039;s not working because i still have arthritis pain."