"i was put on this for a while.  it made me very depressed, anxious and withdrawn.  it was only when my friends told me how bad i was that i realised i was having a real &quot;breakdown&quot; on it.  i went to see my doctor who changed me to sertraline which suits me a lot better.  i was depressed before i took duloxetine but i went in to a very dark place that i had trouble getting out off.  we are all different and different medication suit different people."