"i have been on wellbutrin for about four months. i can definitely say that it works very well. my symptoms before taking it were: mood swings, constant fatigue, irritable, very low to nonexistent sex drive &amp; not able to finish anything i started. my first two weeks on wellbutrin i had a rough go with side effects. side effects were: couldn&#039;t sleep. heavy/tight chest which resulted in a panic attack. itchy palms &amp; feet. i wanted so bad to stop taking it but very glad i didn&#039;t. i feel great now and have lost 15lbs. the sex drive has come back full force. advice: take benadryl those first few weeks to help you sleep. best choice i have made was asking my doctor for help."