"this is the first anxiety medicine i have ever been on, and it is by far the worst experience ever. my moods are anxious, depressed, and irritable. at first, i thought i was just overwhelmed with school and work, after reading some other reviews, i realized it&#039;s the buspar doing it to me. if i take one due to an anxiety attack, about an hour later i am crying and talking about how much i hate myself, then about 30 minutes after that stops, i get extremely irritable and everything makes me mad. i&#039;ve quit taking it until my follow up appointment and i can get it changed. i will never try this again."