"after changing jobs i was feeling depressed and was having anxiety attacks. although zoloft worked, and the first day or so were fine, i experienced intense prolonged anxiety in the remaining days of the first week. there were a couple of days there when it was relentless and extremely difficult to deal with. i&#039;m on day 6 now and it seems to have passed. i get the odd pang but it goes away reasonably quickly. i feel calmer and more relaxed. much less likely to react to little things. i do feel like my sex drive has dropped and it is harder to orgasm. i have a slight dizzy feeling that&#039;s manageable (i hope it goes away). i also commonly have a dry mouth. lost my appetite. haven&#039;t felt like exercising. only 1 week in."