"i started taking wellbutrin xl 150mg once a day for the first two weeks, back in november. at first i noticed a slight change in my mood. the dr. bumped me up to 300mg once a day. i have gotten a lot better now, not depressed, angry, sad all the time. also before i started taking this i was having awful anxiety attacks to the point where i`d black out and wake up vomiting, i was losing a ton of weight because i was so depressed i had no appetite. although i haven`t experienced weight gain with this medication i still don`t have much of an appetite but i have gone back to my normal weight. drinking while taking this makes the alcohol affect you a lot quicker than usual, also causes me to black out 98% of the time."