"i was on a pretty huge dose of isotretinoin to start off with, and i was taking one pill at night and one in the morning. i can&#039;t remember the exact dosage, but it was pretty high. before being on the pill i had acne pretty much since i hit puberty, but i never really had cystic acne. after about 3 weeks of being on it, my face broke out terribly, all cystic pimples on my cheeks. and i experienced severe breakouts like that for about 5 1/2 months. my face and lips were so dry that it hurt to even touch them or do anything. i took the medicine for about 8 1/2 months. i now do not get more than a few pimples a month and have pretty nice skin, but i am left with terrible scarring on my cheeks. overall the medicine did its job."