"throughout my life i&#039;ve had acne and tried many different treatments. some of them worked and some of them didn&#039;t.  spironolactone is one that definitely works. i was prescribed this medication in conjunction with doxycycline, clindamycin lotion and tretoin cream. my skin has cleared up so much, and i am so pleased. i have been taking all the medication for about 3 months and the spironolactone for the past 2 months. 50 mg every night. my dermatologist recently uped my dosage to 100mg every night because my skin still isn&#039;t 100%. this drug works great! i would definetly recommend taking this medication for acne. i&#039;m so happy that my skin is clearing up and i do not have to be so self conscious over it. now to get rid of these darn scars !!!"