"i have been diagnosed with bipolar 1 severe mania episodes for many years and ptsd.  i am on lamictal, 200mg, topamax 100mg, and abilify 30mg.  this is a wonderful combination and the first time in my life that a combination works with little to no side effects.  i have a significant immediate family history of suicide and although the thoughts are always there i don&#039;t act on them and can ignore them with the help of this medication combo and my severe manic episodes are from 8 to 9 severe episodes a year down to 3 to 4 which for me is almost &quot;normal&quot;. with a little more tweaking of this combination i may be able to get it down a little lower than that, we are working on it.  i&#039;ve been on this combination and changing the dosing for about 2 years now."