"i have bipolar disorder and generalized anxiety. i take bupropion daily and xanax (0.5-1 mg as needed) usually twice a day. i started 3 days ago on 5mg olanzapine (@bedtime) .  wow.  noticed much more stable mood on day 1.  today is day 3 and again, very stable mood and sleeping through the night since starting and am very happy with these results so far.  i have not had a need for xanax since starting. the only side effect i am experiencing so far is fatigue in the morning hours - no change in appetite or other effects mentioned by others in this column.  i will post again in a few months to update my results.  "