"i have been epiduo for about a month now and i have to say it is the most gentle acne med i have ever been on. i was expecting the horror stories of flaking and dry skin that i have read about and i have had zero irritation since using it. overall, it seems to work well but i don&#039;t think it can tackle my severe nodular cystic acne so i think i will have to go back on accutane sadly. please don&#039;t let people scare you away from trying this med though, if  i didn&#039;t have these huge cysts i would rate this a 10 but as most people know, topical can do little for cystic acne which is not this meds fault. overall, my skin is super smooth and i would highly suggest this medication."