"i was hospitalized and couldn&#039;t sleep due to intense anxiety in the hospital. i was given 50mg seroquel. i felt the effects within 20 minutes, but then they kept getting stronger for well over an hour until my perceptions of time and space were very distorted. i couldn&#039;t even sit in a chair without feeling i was going to fall out of it. next i started getting paranoid until 16 hours later i took klonopin and everything went back to normal. if i was at home or work and took seroquel for the first time, it would have been a disaster. i did sleep for a few hours while i was on it, though."