"if you have any history with anxiety and/or depression, stay far away from this pill. i have been on orsythia for 4 months and it&#039;s been miserable. my anxiety is thru the roof, i have panic attacks weekly and throughout the month i would go into a depression where i would just be hating on myself and be completely sad for no reason at all. i also didn&#039;t get my period during any of the &quot;period week&quot; (placebo pills week), instead i would get a period week 2-3 of my pill pack. it also made my breasts hurt for the 2 months, and made me have little to no appetite, i lost 20 pounds while taking this. sharing my experience so other girls don&#039;t have to go thru the same thing. i am using condoms as a contraceptive now, and it is sooo much better."