"been on zoloft 50 mg for 3 weeks and i&#039;m starting to feel like myself again. i have mdd, add, anxiety, panic attacks and insomnia but since taking this medication i am sleeping again and waking up without my alarm which has never happened.  i was a little sick for the first few days however it passed.  my panic attacks are almost gone.  my doctor agreed to increase my dosage to 100 mg to see if i can get a little better i&#039;m almost where i want to be but my negative emotions have subsided tremendously.  i know this road is hard for all of us but don&#039;t give up.  remember the chemical make up in your brain changes overtime, so when something stops working seek help.  best regards!"