"works okay for me. i went on it because cipralex (lexapro) pooped out on me. doesn&#039;t deaden my emotions as much as other drugs. anxiety is pretty much non-existent now but my depression remains. no side effects. i put on a lot of weight on cipralex and it hasn&#039;t come off while on cymbalta, but it hasn&#039;t increased either. i haven&#039;t had any notable side effects. oddly, i did have an irritated sciatic nerve when i started cymbalta and while i wasn&#039;t put on it for that, it did kind of help that too."