"i fell over a year ago and have had chronic back pain ever since. i have bulging discs in l3,4 and 5, degenerating discs, and spinal stenosis. i have tried norco, which no longer works. i recently tried nucynta (no pain relief and very tired side effects), so i am sticking with the opana. overall it does a pretty good job with pain. i just feel like my tolerance is building up over the 9 or so months i have been taking it. i take 20 er first thing in the morning, and 10 mg ir one or two more times during the day. i still take norco for breakthrough pain, but even that doesn&#039;t seem to touch the pain anymore... i recommend opana for pain relief and i can still work with a clear head!"