"i was diagnosed with a rare form of lupus (as a teen) 24 years ago, 6years later with raynauds and fibromyalgia. over the years, i have tried many pain medicines, some have helped and some haven&#039;t, but most have had multiple side effects and/or interactions with my other necessary medicines. in 2004 i was in the hospital while i was out of remission and i had a slip and fall, this accident resulted in three herniated discs. since then i&#039;ve been taking avinza 120mg, with vicodin 10/650 for breakthrough pain and i can honestly say, this is the best pain coverage i&#039;ve had in 24 years with only 1 side effect.... constipation, which miralax takes care of."