"i have been on sprintec for a month now, and have not had a problem with weight gain, but for the first 2-3 weeks my skin was terrible! it cleared up after that, however. i don&#039;t feel hungry as often because i almost constantly feel nauseous and have headaches. the most notable side effect is the cramps. even though i&#039;m not on my period, i have terrible cramps that makes it feel like i am! got to my first week of white pills and no period."