"i had a reverse shoulder replacement, august 23, 2017. i was given a nerve block as well as an injection of exparel. it made recovery so much easier! the nerve block didn&#039;t wear off for 24 hours and the exparel lasted for about 3 days. to be spared the immediate pain from major surgery for those first few days was such a blessing. especially compared to my total knee replacement 28 years ago, where i was in agony from the moment i woke up from surgery. wonderful results!"