"i started taking deplin 2 months ago in addition to the 300 mg. of wellbutrin i had already been taking for several years. i was experiencing a very low level of chronic depression but generally okay. the doctor recommended i try deplin to see whether it would increase my level of well-being. i could swear i feel a lot more depressed with the deplin. nothing has changed in terms of life style over the past few months, so i can&#039;t think of any other explanation. needless to say, i&#039;m going to stop taking it. i had no idea it might worsen my symptoms."