"started off with 25mgs of deptran to help with my sleep, anxiety and mild depression. i slowly increased to 50 and once i hit 75mgs i experienced serve sedation during the daytime. i found it hard to get out of bed, to function and ended up resting on my couch for up to 2 hours per day after getting out of bed! i heard it is good for some people who have trouble staying asleep but my problem was that exact opposite. i have trouble drifting into sleep.  deptran(doxepine) increased my anxiety/nervousness, gave me headaches, puffy eyes, tremors and made me too tired to function properly and it wasn&#039;t even helping me get to sleep! i was on this medication for 3 months so i gave it a decent try. still weaning off this medication as i write this."