"i began taking ortho primarily to help regulate my periods, which are both very irregular and heavy. i typically don&#039;t have very severe cramps, so i can&#039;t comment on that. however, about a month into taking this, i started experiencing extreme nausea and about weekly vomiting. at the time, i was dealing with a ton of stress/anxiety, so i partially attribute my illness to that. the nausea/vomiting was severe, seemingly random (but commonly occurred at night/early morning), leaving me not wanting to do anything/go out, feeling constantly tired &amp; run down, and with no appetite whatsoever as the thought of food made me ill. about 3.5 months later, i stopped taking ortho and i haven&#039;t vomited since. just be careful in trying different bcs."