"i swear this pill made me so anxious. i would have so many panic attacks and always feeling the worst was about to happen. it always got better on the period week...the week not on the pill (obvi). i don&#039;t know....i don&#039;t recommend this pill to someone who may struggle with anxiety or depression. i did perfectly fine on ortho tri cycline other than i had switched due to the irritability i felt. i then realized, i&#039;d rather be a grump than always going in panic mode."