"i&#039;ve been on this pairing of drugs for two months and have lost 16 pounds. my appetite is low, and i find i have no trouble sleeping and am not hyped up by the phentermine. i did have to switch to a slow release version of the topiramate, as the regular version gave me tongue ulcers that hurt so badly i could barely eat or drink. i like these meds. they&#039;re working well for me. i&#039;m 51, have about 80 pounds to lose and am finally able to control my appetite. i&#039;m learning new habits and portion sizes. next . . . getting to the gym~"