"i used pristiq to treat anxiety/panic/depression after trying a few other meds that didn&#039;t work well a few years ago. cymbalta was one that did work better when trying to find the right one but not quite as well. i eventually switched to prozac due to cost, after that worked well for a year or two and eventually tapered off medicines all together. had another episode and tried prozac again and then celexa, neither of which worked well. i just switched back to pristiq and feel like i can literally tell the difference after only a day. i do know you need to take each day and at the same time to avoid withdrawal symptoms but i was able to get off it pretty easy in the past by switching to prozac and then tapering. hoping for the best!"