"so i don&#039;t have a major acne problem. i&#039;m 23 and i had like 4 pimples and one was very stubborn on my cheek it wouldn&#039;t go away. so i asked my dermatologist what i should do and she gave me some epiduo cream to try. i put it on right before bed and the first day it was fine and i noticed a reduction in my pimple so i tried it the second night. when i woke up the next morning my face was burning and the areas i applied this cream were so dry and flaky. i honestly would rather tolerate the ugly pimples over the side effects i got from this cream. over all i hated this cream. if you have sensitive skin i would avoid using this, go for veltin instead it&#039;s much more gentle and effective for acne."