"so far  this is absolutely the best aid in losing weight for me.  i had lost 75 lbs in 2011 with weight watchers but gained about 38 lbs back between 2012 and 2014.  i went to the doctor and he put me on phentermine &amp; chromium picolinate. i have been on this since 8/23/14. in 6 wks i have lost 25 lbs.  it has significantly decreased my appetite to where i don&#039;t even think about eating and have to remind myself to do so.  the only side effects i have had are dry mouth, which causes me to drink water constantly (so not a bad thing), mild insomnia the first 2 wks &amp; constipation, for which i just take a supplement.  but you have to eat right.  reduced carbs for sure.  weight watchers taught me healthy eating so you do have to change your food."