"i was on 50mg 2x a day for only 2 weeks on it. my skin broke our even worse than it was before i started and it. within days of being on it i was so thirsty all the time causing me to go to the bathroom constantly. it tore me up causing intestinal problems,but the worse side effect was it turned me into a raging maniac! far worse than when i used to have pms. it was scary &amp; horrible to feel like that.i had little tolerance &amp; patience and would get upset over things i used to laugh at. before i could call my dermatologist i had a appointment with my family dr who took me off it immediately and sent me for blood tests.i can&#039;t wait for it to get out of my system."