"i have spent years going through one anti-depressant after another.  i even did ect treatments and nothing worked.  my psychiatrist then put me on desipramine and i have never looked back.  i have energy, i can concentrate, get out of bed, and function for the first time in years.  i&#039;ve been taking it for 6 months now and have not had to increase the dosage, either.  it was truly a godsend."