"i started this medication due to depression and uncontrollable panic attacks and anxiety. i started on 10mg and had very bad nausea, very tired and no appetite. the first two weeks were the same but the definitely by the 3rd week i could feel by body calming down and was quite pleased. unfortunately, i started having awful tingling and burning in my arms, mostly the left. now i have titrated off and now on effexor, but i am still having the burning and tingling in the arm but have had only 1 panic attack. the first two weeks are hard but hang in there. it will be worth it!!!! i wanted to give up as well but i had to think about my family and that pushed me through. i&#039;m not 100% but i can drive and socialize now without getting as panicked."