"i have fibromyalgia, i have tried standard treatments for this condition and nothing has worked except norco 10 -325 twice a day and tramadol 100 mg  two times a day.i have been on this same does now for 4 years and it does the job. the only side effect that i notice is with night time leg cramps i have tried to see what caused the leg cramping and i am determined it to be the norco. when i stopped taking it the leg cramps went away. i adjusted the time i take norco and no longer take it after 5 in the evening and it seems to help. i alternate the tramadol, take my dose in the morning about 6am when i wake up and take norco at around 10am and 5pm and then tramadol about 9pm and it works perfect and seems to control my pain."