"i have osteoarthritis. as i live in england, my treatment, thankfully, is free at the point of service. otherwise i now could not possibly afford treatment, and without both tramadol and co-dydromol the pain is intolerable.

even both together do not wholly alleviate the pain and i do find that after a few weeks i my body becomes &#039;over-tolerant&#039; of these medicines and the pain again increases.

when this occurs, i either cut down from full dose or try and stop for a few days, and this seems to help these &#039;analgesics&#039; to work fully again when i increase to full dose again. however, the pain in the interim is so unbearable i can do little physically, and stairs are almost completely unmanageable."