"contrary to what a subject said , claiming this medicine got him depressed, i would say that my life before it was of depression, loneliness, extremely low self-esteem and self-worth. after i started taking it, my hopes were raised up. the results were amazing just after one month. unfortunately i had to redo the treatment. today i still take one box or two now and then. had it not been for this medicine, my face skin would be now badly damaged and i&#039;d still be covered in grade 3 and even grade 4 acne. my life, i don&#039;t even want to think about what it would be like now if i  hadn&#039;t done these treatments. i do recommend roacutan. endure the side effects no matter how harsh they may be in your body. it will pay off eventually."