"my experience with depo-provera was horrible. i had horrible mood swings and i spotted the entire 3 months until the shot left my system. then my period didn&#039;t show up for 5 months. my face started breaking out, not badly, but enough for people to notice. i also developed cysts on my ovaries that began rupturing and was put in the hospital for them. it has been almost a year and my face is finally starting to clear up. but i didn&#039;t get pregnant...so i guess that is one advantage."