"i started on 10 mg of brintellix and took it at night. i did not have any side effects in the first two days, except that i felt a little bit more depressed at night on day two.  i wasn&#039;t sure if it was due to the medication or not. on the third day, i had a mental breakdown. i had one negative thought after another and my mind was racing. i started crying and got suicidal. i was so worried for my safety so i was thinking about going to the er, but i stuck it out and eventually the suicidal thoughts disappeared. after that incident, i got off of brintellix. it was the worst experience i&#039;ve had from a medication."