"my doctor gave me an 800 mg ibuprofen about an hour before insertion.  while they attempted to insert the mirena (which i had originally planned on getting) i experienced horrible pain for nearly 10 minutes.  i&#039;m 20 and have never had children and it was one of the most painful experiences of my entire life.  i usually have very painful period cramps and this still felt much worse.  finally, they asked if i&#039;d rather have the skyla, which is smaller and might accommodate my tiny cervix better.  in comparison, the skyla insertion was much quicker and less painful.  after the procedure i did throw up once due to the intense pain, but after a few days i experienced little to no side effects.  i do recommend taking the day off of work though."