"when i first took seroquel, i had the side effects of a type of motion sickness, as my head would whirl about, and i never knew if i was whirling or the surroundings were.  i didn&#039;t want to stay on it, but was advised to give it longer. and to change from xr to regular.  i did,  and after about 6 weeks (from memory) i adjusted to it.  yes, i was so tired, went to cut a 300mg into halves, then to 200mg&#039;s, now to 300 mg again.  seroquel works for me, i&#039;ve been on it for approx 18mnths or so.  i sleep, my mind doesn&#039;t race or think or roam.  i get a deep sleep.  i was advised to get up early and it will wear off- yes, that happens. but it&#039;s not easy."