"i started using zoloft at the recommendation of my doctor who thought i may be experiencing mild depression.  i take 25 mg before bedtime and have been able to sleep peacefully (one thing i could not do before zoloft).  i am not sure if my better overall mood is because of the drug or the fact that i am finally getting sleep at night, but i no longer burst into tears, scream at my family or contend with overwhelming negativity as i was prior to taking zoloft.  the symptoms associated with pms have definitely improved, as well.  i had side effects (shaking, dilated pupils, nausea) for the first two weeks, but have been fine since.  my doctor recommended that i take vitamin b with the medication daily - works well."