"i have been on sertraline 50 mg for 6 months, prescribed for frequent crying spells and difficulty accomplishing anything owing to low feelings in the wake of a divorce and two bereavements. after 2 weeks, i started to feel quite a lot better. the crying virtually stopped, although i still cry occasionally for a few minutes if upset about something.  in the first month, i felt quite euphoric and full of new energy, but now i just feel normal, calm, rational, more industrious and sociable. the drug has not affected my sleep or ability to concentrate. i have, however, gained weight, as well as a sweet tooth. i also often awake with clenched teeth. i am occasionally oddly absent-minded, but better overall, and happier."