"this medication has completely changed my life.  i was on 45 mg. mscontin and 10mg. percosets for breakthroughs and was breaking through every day, multiple times a day.  then my doctor put me on fentanyl patches (generic duragesic), 25 mcg/hr., changed every 3 days.  literally, my life changed overnight.  pain is now down to &quot;noise&quot; level--yeah, i&#039;m not 100% pain free, but no pain med can do that.  now, i breakthrough maybe once over the 3-day period."