"i&#039;m a 32 year old guy with stage iv malignant melanoma.  i take ms contin 30mg every 8 hours and until the recent oxycodone i.r. shortage, roxicodone 15mg for breakthrough pain.  today my doc prescribed percocet 10/325 to substitute for the roxicodone.  at the risk of sounding like a junkie- hydrocodone products (e.g. vicodin/vicoprofen/lortab, etc.) have been my opioids of choice.  i am however, very impressed with the percocet 10/325.  it works quickly and completely without the &quot;zoned out&quot; feeling i get with methadone or fentanyl. all in all - good stuff."