"i started prisiq on 3/22/10. the main side effects were not sleeping well and night sweats. this lasted only about 4 nights. a bit of nausea, not enought that i couldn&#039;t handle and that was it. i am now on my 3rd week and i am doing fine. i do feel much better, and have more energy, since before the pristiq, all i was doing was sleeping. if someone has never taken an antidepressant, the side effects can be alarming. i went cookoo and no sex drive on zoloft and cymbalta. pristiq, whatever is different about this srni seems to keep me at an even keel. i will give pristiq at least 3 months before i give a full report."