"i am almost 24 and have been on pristiq for about 5 weeks. i am now up to 100 mg but started at 50. i have no negative side effects besides maybe a light headache. i have been on over 10 anti-depressents in the past with nothing but bad side effects and had sworn them off 6 years ago. nothing worked for my anxiety and depression in the past besides of course my take as needed klonopin. pristig has been good. no side effects or appetite increase. i am also going through an extremely tough and stressful time in life at this point and once i was upped to 100 mg, i have noticed an increase in my mood positively. like i said, i had sworn off meds for years, but i feel like this one may be working. give it a try and work with your doctor"