"i have been on contrave since mid-dec &#039;14. i weigh every 3 months and in march 2015, i had lost 40 lbs. i wish it was a lot more but i know slow weight loss is the best way to assist in keeping it off. i eat approx 500 calories/day and have one &quot;cheat&quot; day where i eat whatever i want. i have found on those &quot;cheat&quot; days, i can not even begin to eat the amount i used to eat. now part of that is from lower intake of food, but the contrave does make me feel fuller even on normal days. i have found that the hunger/appetite comes back and then will go away few times each month. when i was ramping up, it did make me nauseous and i can&#039;t stand to be nauseous but i got through it. worse side effect right now is a horrible bitter taste after sleeping"