"i have been on paroxitene 60mg for seven years now and in the last five months i started to have mass anxiety crying all the time and depressed. i did loose my friend to cancer and i am finding employment and relationship with partner was not going well. my partner became mentally unwell and that affected me too. i saw my specialist and he said sounds like the paroxetine  is not working for you anymore you properly have reached a tolerance to the paroxetine. so my specialist looked on his computer and said lets put you on mirtazapene (avanza) and on the third to fourth day i started to feel more better in myself. i am weaning off the paroxetine it&#039;s been 2 weeks from 60mg to 40mg and now two more weeks from 40mg to 20mg. good things take time"