"i&#039;ve been on seroquel for 4 years on 300mg. everyday i woke up like a zombie had no energy. everything has dark and gloomy, plus i had no energy whatsoever. i researched bupropion i&#039;m on 150mg only once a day. i&#039;m still coming off seroquel from 300/150/50mg. since taking bupropion i have so much more energy everything seems brighter. i seem more interested in simple things, more organized. i actually notice myself laughing at little things, i feel like i forgot to laugh so it was a strange feeling when i was. i&#039;m still a bit groggy coming off the seroquel but hopefully this will work for me."