"i had major ankle surgery. this was one of the medication i was given.  you have to keep it refrigerated, but one opened it can be a room temp. i want you to know my throat hurt so bad after surgery too.  i had a nerve block done also so i waited till the next day to use this medication.  i read about the burning, but didn&#039;t realize it was like someone placing burning coals in you nose.  i was like omg omg for about 5 mins. then all of the sudden no pain, not even my throat was hurting anymore.  after about 6 hrs. i did it again, it did hurt, but not as bad a the first time.  the only thing was when it was wearing off i got a bad headache. other than that no problems.  for someone in moderate to severe pain i would recommend."