"i took cymbalta for about 6 months for clinical depression. although it helped the depression a lot, i couldn&#039;t stand the side effects. i lost about 20 lbs (i&#039;m already underweight), i started having almost constant migraines, and all i wanted to do was sleep.  it was hard to get through work because i was so tired.  then on my days off, i would only wake up to make dinner for my husband, then i&#039;d be back in bed."