"have been on 15mg for one month.  it helped almost immediately with depression and sleep issues; however after ~ 3 weeks i began having trouble tasting food and drinks properly and have a mild but constant bitter taste in the mouth. first two weeks had the voracious appetite,
but it has subsided significantly.  i intend to see my doc this week about the taste bud issue, and may ask him to get me off of remeron.  also, i&#039;ve been on paxil for the past 7 years (20mg at this time) and perhaps the &quot;taste bud&quot; issue is due to the combination of remeron and paxil."