"divalproex 500 mg taken 2 times daily along with welbutrin 75mg 2 times daily has been a life changer for me. i have tolerated both medication well. the divalproex did not cause any weight gain. in fact, with a better control of my mood i saw much better and more consistent workouts. i lost 5 to 10lbs. my physician started me on 500mg a day for a couple of weeks and then to 500mg 2 times daily to stabilize my mood before introducing the wellbutrin. it was a 6 to 8 week process, but well worth it. i would highly recommend the combination to anyone with mild bipolar."