"i have taken latuda for about 2 weeks for bipolar depression. i also take prozac and depakote. i have never had a medicine work so quickly and dramatically. i can feel again...love for my family...optimism...although i am not sleeping as i did before. i have gone from 12-13 hours/night to 6-8 hours/night. i have had brief episodes of irritability but so far have been able to resolve them quickly. i feel better than i have in years."