"took ortho tri cyclen lo for 3 years, and at the same time i started it, i became engaged. went from semi normal emotionally to severely psychotic- depression, anxiety, thoughts of suicide, etc. i chalked it up to marriage jitters. i suffered for about a year after that before i read something about birth control causing mental problems so i stopped the pill altogether. a month later i started aviane because i was paranoid i&#039;d get pregnant. miraculously the bad thoughts and depression/anxiety disappeared within 2 months.  the downside is my skin is horrible since i started this pill. i had flawless skin on orthro tri-cyclen lo, but i will take zits over anything. if you struggle with depression i&#039;d give this pill a try."