"all i can say is try it and don&#039;t take all reviews at face value - not everyone has brain zaps and puts on a ton of weight because everyone is different. all i know is i suffered from major anxiety and depression (tried to get by without meds for some time).  i had fluoxetine and citalopram - the first only helped with depression and the second gave me heart palps.  now on cymbalta i am feeling normal and wake up refreshed and ready to face the day. the first week was a bit crazy, felt like on a bad trip. then felt great for a week, then low again for two and now i am fine (taken them for about 8 weeks now).  i also have the motivation now to lose weight which i have done so i am fairly optimistic. 8 stars because haven&#039;t taken it long term yet."