"i just came off 112.5mg/day of effexor which was absolutely horrible. my doctor has put me on 10mg of brintellix. i have immediately begun feeling better mentally and emotionally for the first time in months, even while dealing with these withdrawal symptoms. i didn&#039;t have high hopes given my past experiences with antidepressants and honestly was about ready to give up on medication all together. i am experiencing some nausea which could be from withdrawing, the brintellix, or most likely both. seriously, for how bad i am feeling physically from the effexor i am absolutely amazed that i can feel this positive mentally. i&#039;ll update when the physical symptoms subside."