"i wanted to put up my experience with wellbutrin, because some people may have the same issues that i had with the drug. in the onset of taking wellbutrin, i had, each time, slight to severe anxiety and almost worsening of symptoms, in proportion to how hefty of a dosage i started off with. long story short, i&#039;m never getting off of it again, but if someone is trying to get on wellbutrin and is having awful anxiety and no sleep or appetite like i did.... you might ask your doctor if you can take a small dosage and taper up. i literally started with 18.5mg and i still had a few symptoms from that, but i could also feel improvement at the same time. i increased by 18.5 more each 3-7 days. i&#039;m not on 300&#039;s and knock on wood, my life is back."