"i&#039;ve taken contrave and 0.25mg of topamax for 7 days. i&#039;ve lost 6 lbs. very happy. side effect symptoms include: mental fog, short term memory loss, anxiety, depression. the brain fog and anxiety/depression are awful. i&#039;m hoping the symptoms go away soon. haven&#039;t experienced the headaches (maybe b/c of the toprimate) &amp; no night sweats! meds have eliminated cravings &amp; emotional eating. thought wellbuterin was an anti-depressant but i&#039;m uncharacteristically depressed &amp; anxious. so weird! is this how everyone else is feeling? i plan to lose 30 lbs by february. i&#039;ll update."