"i&#039;ve taken cymbalta for almost a year for depression and anxiety. i&#039;m also taking buspar. my anxiety and depression are noticeably improved. i have tried many of the ssri&#039;s without any help, but this snri is great. i take 40mg/day. i&#039;ve been as high as 60mg/day but found no help at the higher dosage. the only side effect might be a bit of drowsiness. i tried to reduce my dosage quickly and found this is not a drug one wants to &#039;cold-turkey&#039; to get off the drug. the benefits far exceed any bad side effects."