"i have been taking the general medication not the brand name for about 3 months now and after a couple of weeks i would be in a good mood and the little things that would annoy me wouldn&#039;t anymore. i wanted to do things and not just be home all the time. but recently i have relapsed and went up on my dose from 300mg to 450mg and still feel depressed. i don&#039;t know if my body is just tolerating it or what but i hope my depression improves."