"i&#039;ve been taking vyvanse for a couple of months and i&#039;ve have learned that the first couple of weeks taking the medication is really the hardest when it comes to side effects. i suffered from dry mouth, loss of appetite, head aches, some but very few mood swings. as far as sleep, i crash at the end of the day which can be due to this medication. i am irritable every now and then, but before i was very frustrated with everyday activities. it gives me energy for the most part. i&#039;m not shaky or nervous like i was on adderall xr. i haven&#039;t lost a ton of weight on vyvanse unlike adderall which i lost 60 pounds on within 4 months. "