"i am 22 and i have always had moderate acne on my forehead since i was 13. i first started with 100mg of spiro which caused a horrible initial breakout. i stopped taking it for 1 month and started it again but on 50mg and it really cleared my skin. within one month i started getting a terrible headache that lasted 1 week it was so unbearable i stopped taking the pill for a week now and my headache is completely gone. i don&#039;t know if this happened because my diet consists of mostly salt food, but i was seriously scared i thought i had a brain tumor. this pill is a diuretic so maybe it&#039;ll work well to those whom have a well balanced diet, but as soon as you feel side effects you should stop it immediately!!! :("