"i started taking zoloft when i was 16. i was sent to the hospital twice for suicidal actions and my doctors upped my initial dose from 25mg to 200mg. i was supposed to go up to 300mg but i was really sick of the dosage being upped and nothing happening. to be completely honest, it took 2-3 months to kick in for me. i&#039;ve been diagnosed with psychotic depression/possibly schizophrenia spectrum. now that the medicine has had some time to work into my system, i&#039;ve felt much better. not 100% my old self, but capable of functioning and taking care of myself. i wasn&#039;t able to get out of bed for days on end at my worst. the side effects are totally manageable and worth it. my psychosis apparently calms down when i&#039;m feeling less down which is a relief."