"i&#039;ve been bi polar for over 20 years and have tried practically every mood stabilizer and antidepressant there is and some would work for awhile then poop out. saphris is like a miracle medicine. i don&#039;t feel depressed, i have more energy and motivation and my moods are stable. i take one 10 mg tab at bedtime and wake up the next morning feeling alive and ready for the day. i would encourage anyone who is suffering from bipolar depression and mood swings to give this medicine a try. you won&#039;t be disappointed.  one caveat though is without insurance it is very expensive."