"when my psychiatrist finally put me on 1 mg. of rexulti, it was a life saver. my latest depressive episode seemed intractable until then, but a major drawback has been sleep interruption, often as early as 3 am. my mind races and it&#039;s often more fun to get up than to stay in bed. i rarely sleep beyond 6 am, no matter how late i go to sleep. my much valued afternoon naps have also become infrequent too. i also take pamelor 75 mg. per day and seroquel 75 mg. per day. doctor said that i&#039;d have to come off the seroquel since it&#039;s the same drug family as the rexulti. well, i&#039;ve decided to get off the rexulti and keep my seroquel since the seroquel helps me sleep and wears off by morning. rexulti is absurdly expensive."