"i have been treated for severe cyclic depressions (atypical), anxiety, and ocd since college and i am 47. without effective medication, my illness is debilitating. in 1993, after trying many different antidepressants, i urged my psychiatrist to prescribe me the monoamine oxidase inhibitor, nardil. wow....somebody switched the lights on and the symptoms off. 90% of the time i was in remission with only brief minor periods of symptoms. nardil was reformulated and stopped working, so i switched to parnate. 160mg/day give 100% symptom relief (with 1200mg/day lithium). i mentally feel like i&#039;m 20, bursting with mental energy. many considered me brilliant prior to parnate; but after years on it, my cognitive skills, retention, and creativity reached a new level."