"i&#039;ve been on it for 1 week now  suffering from bad sciatic pain caused by a herniated disc s1-l5. i was taking 6-8 ibuprofen a day and was still in pain. with only the entry dose of 1 300mg a day and 2 ibuprophen a day i can function almost normally until this disc heals...absolutely amazing medication. i won&#039;t don&#039;t plan to ramp up to the 900mg a day, getting great results with the 300. i was a little fuzzy the first day, but fine after that."