"i went on cymbalta for my fibromyalgia pain and depression.  i never had any real early side effects like nausea or vomiting, but i have gained 15 pounds. my meds have helped me and i  don&#039;t suffer from as many days of dreading to get out of bed. cymbalta has helped me greatly and if some extra weight is the price i have to pay to be happy then i can deal with that."