"started out on 300 mgs 1 x per day. can&#039;t say it helped or didn&#039;t. the dose was lowered to 75 mgs at one point to see if it was the reason for my memory loss. supposedly i had an acute stroke with partial blockage in my neck. i have been on it 15 years doctors recomendations. last 7 years have been on 150 mg&#039;s 1 x per day. mind comes and goes. sometimes i can&#039;t remember my husbands name. i had no visual signs of stroke. they said it was an old stroke i never noticed. i also take xanax 2 mgs per day. gabapentin 300 mgs per day. geodon 40 mgs per day. bisoprolol 10 mgs 1 x a day. diabetic. take insulin. anxiety is gone. i do need to figure out what is causing my memory to come and go. wondering if anyone else has this problem on effexor er."