"i have taken almost every drug out there. with so many drugs/so many different side effects, because of this i have been off all drugs for a couple of years, i feel the need to go on something for depression. i was so worried about side effects of weight gain or hair loss, that i asked my doctor for something that would avoid these two side effects. i have been on pristiq for almost 2 weeks...i have mild headaches, frequent urination, constipation, and insomnia so far. i am hoping with monitoring this that maybe if i change the time that i take it and try to add fiber to my diet, and try to drink less fluids closer to bed time to help. i have had worse side effects with other medicines, so i will stay on longer to see if i notice a difference."