"i take 40 mg of latuda nightly with a titration dose of 25-75 mg lamogotrine (lamictal) for bipolar i. within a day of taking it, my mood brightened, i was able to wake up in the morning without malaise, and experienced a loss of appetite. i much prefer this to depakote and wellbutrin. i was not compliant with the depakote due to the side effects of a huge appetite and the fact that it made me feel like a zombie. after a manic episode, i needed to recommit to compliance again, but abruptly stopped taking depakote and risperdone (prescribed right after manic episode) due to side effects. after a couple of weeks of no medicines, the latuda/lamotrigine cocktail made life so much brighter."