"i opted to start depo after giving birth to my first born. prior to taking it, i was having problems with anxiety and infrequent panic attacks following his birth; as, i assume, many new mothers do. following the injection was one of the worst bouts of depression i have ever experienced in my life. i went to several psychiatrists as well as my gp, seeking treatment. because i am breastfeeding there was not but so many medicines they could try. celexa made me hallucinate, and a week or so into zoloft i experienced a panic attack that i couldn&#039;t calm down from. i began smoking again to cope. we&#039;re a low income family, and i couldn&#039;t afford to keep going to the doctor. i eventually gave up. the injection wore off, and the depression did too."