"i&#039;ve had acne for two years (currently in year 9) and have tried all creams, but the creams never used to work for me since it wasn&#039;t my skin that caused the pimples, apparently there was just too much hormone production, so the dr. prescribed me with 50mg of doxycycline about two and a half weeks ago. the first week there weren&#039;t any signs of success, the second week it just seemed to get worse, (which everyone says is the side affect of this drug) but i haven&#039;t experienced the third week of being on this drug so i just hope my pimples clear up."