"i first reviewed this in november 2010, (see past comments). i have since had alif surgery (anterior multi level fusion l-3, 4 and 5), and am feeling better everyday. i have been prescribed every painkiller in the book for the past year and a half, nothing provides the pain relief with minimal side effects that nucynta does. nothing. in the hospital i was injected with 2mg morphine every 3 hours plus oxycodone every 4 hours and was a complete zombie. left the hospital, took 100mg nucynta and received the same relief with no ill effects. it&#039;s been 2 weeks. now taking 50mg 3x daily."