"i got nexplanon about a month and a half ago. as i&#039;ve only ever used low dose estrogen birth control pills, nexplanon sent my mood swings through the roof within the first two weeks. i mean out of control, cry-in-my-car-at-work , ugly mood swings. it was awful. since those first two weeks things have gotten exponentially better. the mood swings aren&#039;t really happening anymore, i don&#039;t feel depressed/anxious/sad at all. my skin completely cleared up and i&#039;ve been losing weight. the spotting has lightened up and i feel normal again. every body is different- but this is definitely worth a try! if it weren&#039;t for the wild mood swings i&#039;d rate a full 10."