"i was on effexor for over 10 yrs. i finally got off this in dec. 2013 and as of today, july 2015, i&#039;m still having those brain zips several times a day. last july, i started with a vibration and severe pain in my feet. it&#039;s all nerve connected and i think it&#039;s from long term use of effexor. this medication works great for depression but the side effects are not worth it."