"i have been on pristiq for about 14 days now...i love it ! i have never been on any medications. i have 5 year old twins and felt tired, moody and couldn&#039;t wait until bed time. i am up early now and have the energy to deal with it all. i have noticed some weight loss, which i really don&#039;t need to lose any, but a few pounds would be nice. i only had side effects for a few days. my life is going great now."