"i went on depo because i have horrible long periods and was constantly forgetting to take my pills which was makin my periods worse. i got my first shot on the first day on my period about a year ago and within two days my period was gone. i spotted a little the next month but haven&#039;t bled at all since! it&#039;s been amazing. i have been very good about getting my shots every 3 months on the day. my body did not react well to estrogen but reacts very well to the hormones in the shot. my acne got slightly worse but i also lost about 10 pounds since i&#039;ve been on it. i love the depo shot! i haven&#039;t had my period or period side effects and almost a year and it&#039;s made my life so much better."