"i took paroxetine for 13 years, and i felt great all the time. it is wonderful for treating anxiety, but i took myself off it because i am on tramadol and it warns not to take it with ssri&#039;s since it could cause seratonin syndrome. i really miss it, but i had no other option. i need the tramadol for spine pain. don&#039;t know what to take in its place. by the way, neither my dr or my pharmacist worry about taking the two together, but i&#039;m 72 and i don&#039;t need any more problems."