"i&#039;ve been using vicoprofen for more than 3 years. i take 3 per day for the pain of fibromyalgia and also lingering pain from having had the kneecap dislocated due to a fall. most of the time i take it on an empty stomach with no problem. also, i&#039;ve never had a weight gain because of it or constipation. i have normal daily bowel movements. i can function at a higher than normal level. no problems for me taking vicoprofen."