"i&#039;m 25 and have been on depo for about 14 months and the only good thing is no periods!! but i still have cramps from time to time.... since using depo i have been diagnosed with anxiety and outrageous depression to the point i&#039;m on meds... i noticed alot of stomach pain, tingling in hands or feet, feeling nauseated when eating food, hair lost and weight gain. went from size 16 to 22.. always in a down mood and it killed my sex drive this drug is definitely not for me... been off for 4 months now and still no sign of a period.... hopefully it changes soon"