"i&#039;ve been on 200mg bupropion (regular release, not sr/xr)  total for over 5 years along with an ssri. i have depression and add. the bupropion helps the focus,  though it can make me feel impatient and irritable when it &quot;peaks&quot;. i like it because it helps the depression,  adhd and restless legs and helps offset the negative effect of ssris on libido. it does make intrusive images/thoughts worse. i will have sudden mental images of violence (for instance, suddenly getting slammed into by another car while driving) but i&#039;m used to my brain being a pest so i let it roll off me. helps with motivation and planning and organization. can cause dry mouth and slight ringing in the ears."