"i have been taking 100mg of this medicine nightly before bed for nearly a year now. i had an awful case of anxiety based depression that ruined me my senior year of high school and left me in the throes of a personal break down. i went to my doctor and she submitted me to this experimental medicine screen after a previous attempt of cymbalta left me no where. when i started taking these pills, it was like a miracle had happened to me. my anxiety virtually disappeared. it was the biggest relief i had experienced in my life. i no longer had issues talking to people and i began to excel in my work once again. only complaints are extreme withdrawal symptoms and it is much less effective for me while i am on my period."