"i&#039;ve been taking cymbalta for depression for two and a half years. my doctor titrated me up to 120mg. i was at 120mg for over two and a half years and almost constantly i was severely depressed, severe anxiety, some paranoia, no energy, over reaction, self harm, extreme anger, just to name a few. that&#039;s not to say i do have some of those problems normally, but not as severe or as constant. so cymbalta was overlooked as a cause to my worsening issues. two weeks ago i was admitted into an inpatient hospital to basically save my life. while i was in there i was abruptly taken off, then titrated up to 60mg. i&#039;m a totally different person now. i did a complete 180&deg;. i can&#039;t believe what a difference it makes being on the right dose."