"i was given butorphanol for severe abdominal pain related to crohn&#039;s disease when none of the typical meds worked for me. it is amazingly effective. the first time i took this nasal spray my pain disappeared in about 7 minutes. nothing has ever worked for my pain before until taking this. and since i have crohn&#039;s disease, the nasal spray is brilliant because it doesn&#039;t go through the digestive system and cause other symptoms. made me a little sleepy, but less each time i take it. it&#039;s been a miracle for me."