"i have taken tri sprintec for 2 months and i refuse to start the third month. it makes me terribly nauseous, to the point where i will throw up about 4 times a day. (it happened so often i thought i was actually pregnant, which i am not). i have never been a sad person but since i started taking this pill i have been extremely depressed and have had terrible mood swings. it also causes tenderness of my boobs that i&#039;ve never felt before and is extremely uncomfortable. everyone&#039;s bodies are different but i had a horrible experience with this pill."