"i was on wellbutrin years ago, and it helped.  in the last couple weeks, i have been suicidal and very depressed.  my doctor put me back on the wellbutrin, and 2 days later i&#039;m ridiculously happy!  i think it&#039;s worth the side effects, but some may not.  i&#039;ve experienced: insomnia, lack of appetite, horrible nausea, and incessant twitching (every 8 seconds or so).  the insomnia is horrible.  i&#039;ve gotten about 2 hours of sleep in the last 3 days.  lack of appetite is okay with me, i needed to lose weight anyways!  ringing in the ears is something i&#039;ll deal with, but the nausea and twitching are the worst by far.  i look like i&#039;m having a small seizure sometimes, and the nausea is just...ugh..."