"i&#039;m not a doctor, but i want everyone who&#039;s reading this to know: everyone reacts differently to medicine. pristiq didn&#039;t work for me, unfortunately. i was on the lowest mg. it didn&#039;t do anything when i took it, but man...when i didn&#039;t take it...it was like i was having an &quot;out of body experience.&quot; it was the weirdest feeling. not like a &quot;cool&quot; high. it was uncomfortable and annoying. i kept taking it in hopes of it helping my suicidal thoughts, and major anxiety. now, all antidepressants can increase suicidal thoughts. pristiq definitely increased these bad thoughts. i threw up before work (anxiety) &amp; was always a nervous wreck. i&#039;m off the medicine now. going back to the doctors to talk about other options. god bless all of you."