"bipolar 2 (depression). still early days, and i&#039;m still on a low dose (50 mg) titrating up towards 200 mg, heading into week 4. at first i didn&#039;t notice any effect at all, just minor side effects, e.g. hand tremors, itching, waking up every night and not being able to go back to sleep. looking back, i realize that after ~2 weeks i slowly started getting more done. after a year of not cleaning and laundry never getting done and dishes sitting for weeks, i started to make headway with those things. it didn&#039;t happen from one day to another, and it&#039;s still not easy, but things like that get done. that&#039;s the difference. crossing my fingers that the progress continues!"