"i have suffered with moderate to severe depression my entire life.  last august, after 9 years on effexor, i stopped taking it because of the side effects.  

i tried using supplements as recommended by  julia ross in her book the mood cure, but they were not effective for me.  my depression became so severe last oct. that i had to go back on to an anti-depressant (bupropion) but this medication made my depression much worse.  i was then put onto trintellix in april.  the trintellix was helpful, but side effects soon began to appear.  

i happened upon an article about a psychiatrist who had used niacin for treating depression.   when i googled niacin and depression, i came upon many other blogs and comments from other people who also found niacin to be effective against their struggles with depression. 

 i was desperate to find an alternative to taking anti-depressants, so 4 weeks ago, i began supplementing with niacin plus vitamin c.   (i had already been taking a vitamin b multi, magnesium, fish oil and vit. d).  i started with 100mcg niacin and have been gradually increasing the dose by 25mcg increments each day.  i use only the regular niacin, not the timed release nor the non-flushing type.

since i started taking the additional niacin &amp; vitamin c,  i find that my depression is/has diminished significantly.  i am no longer suffering from that bottomless well of depressive  feelings that had been with me since last fall.  i stopped taking the trintellix  3 weeks ago and my depression has continued to lift."