"i&#039;ve tried many different medications over the years, and pristiq has been the only one that i can seem to tolerate. i started on sample packs at 50 mg for a few months, and it was actually working, until my doctor&#039;s office conveniently ran out. i was forced to go on effexor, and though it may be a similar drug, it is absolutely not the same. i felt shaky, agitated, and suicidal thoughts also came back while on it. 

now finally back on pristiq, and after two days, my anxiety/depression is almost completely gone. it&#039;s like some sort of &quot;switch&quot; went off in my brain. i don&#039;t feel desperate and i&#039;m not texting someone 20 thousand times per day because i feel so suicidal and needy. i am a trashy mess without this drug."