"i have had 7 surgeries, 5 lower back, 2 neck fusions and still have 5 herniated discs in my thoracic spine.  avinza with 10/325 has been a godsend. i also have muscle spasm throughout my back at all times.  i have been taking 120mg every 12 hours with the percocet for breakthrough pain.  add muscle relaxers and i still had pain but could function.  my biggest problem was my last surgery the hospital didn&#039;t have any so they had to work out an equal dosage of dilaudid.  it worked but i was far better with my avinza.  i only wish the hospital would allow you to bring your own, they can administer it. "