"i have very bad treatment resistant depression/anxiety. i was on prozac for a year and it worked wonders until i had to keep going up in dose and the side effects were just to bad. since i have been put on lexapro, welbutrin, vyvanse, and lamictal none worked like the prozac. recently my doctor put back on prozac, 20mg and added 15mg deplin. prozac usually take a month or longer to feel the effects, especially on a low dose. after two weeks i felt good already with no side effects! in fact my sex drive has actually increased. 20mg was never enough for me before and with deplin it&#039;s perfect. i&#039;m so happy."