"i was prescribed the flector patch a little over a month ago for rotator cuff aggravation. i also suffer from osteoarthritis in my knees with one having had meniscus surgery 3.5 years ago, and also sciatica and disc herniation in lower back ect.  i cannot take nsaids orally because they affect my heart rate and blood pressure . i am extremely sensitive to medication.  my ortho doctor prescribed these to try for my shoulder and i was pleasantly surprised that they help as much as they do. i have since tried them for a sciatica flare up, worked very well, and also cut one in half and put each half on a knee last night because i was in a lot of pain , knees are great today! tape to reinforce, stretch patch 1st . i only use as needed not daily."