"i&#039;ve been taking 5mg of trintellix for almost 3 weeks now. i haven&#039;t experienced any nausea or vomiting, but i&#039;ve been really drowsy and light-headed. i also take 5mg of lexapro but that&#039;s a really small dose, so i suppose it&#039;s not actually doing anything. my mood has actually been worse since i started the trintellix. more depressed and more unmotivated. i was hopeful about this drug. my practicioner said it was going to be a &quot;kick in the pants.&quot; nope. now i don&#039;t want to even move."