"this is the best pain medicine i have ever used, and i have used many.  i have a 4 level fusion in my neck that didn&#039;t fuse, and it was attempted twice.  lower back surgery as well.  broken hip, bad left knee, bad left ankle.  i was paralyzed briefly in an atv accident back in &#039;01.   hydrocodone and oxycodone only lasted 2 hours or so.  the pain was about to disable me.  this drug is simply amazing. i do not get &quot;high&quot;, or feel a &quot;buzz&quot;.  no side effects, but possibly some impotence.  taking 30mg every 12 hours, with a 10mg dose 3 times a day for &quot;breakthrough pain&quot;.  after 8 hours or so, the 30mg wears off rather quickly.  many pharmacies don&#039;t stock opana, and i have trouble getting refills when out of town.  keep that in mind."