"i was suffering severe depression from a total inability to cope with a traumatic situation i had been through. pristiq worked wonders the first couple of weeks. i was enjoying life again. silly me, i didn&#039;t pay any attention to the side effect information. it all started with significant weight loss 25 lbs. i originally weighed 120lbs, then i stopped sleeping. i became panicked, one pupil became very dilated. terrible situation."