"i&#039;m 5&#039;4&quot; 45 years old, started at 225, took other meds got to 212, doc put me on these to help with cravings, and just being hungry all the time , started dec 18th, i probably gained some over christmas, this morning i&#039;m 208, no major issues, definitely has helped being hungry, and cravings, on 2:1, friday i&#039;ll move to full dose. i am more regular so no constipation, or diarrhea. i did wake up a few nights with heart palpitations, but i think it was from eating dark chocolate. only reason i&#039;m not giving it a 10 is i&#039;m not on full dose, or long enough to know if it will stay this effective for me."