"i have suffered major depression for many years and have taken almost every ssri that has been on the market.  i recently slipped into a bout of very deep depression and was almost suicidal.  cymbalta pulled me out of it.  i am very thankful for this medication because it brought me back.  however, it was not working at 60mg a day so the doctor increased it to 120mg a day.  i realize that is a high dose but the benefits outweigh the risks by far in my situation.  i was in the deepest darkest depression for about 3 months and almost lost my job over it.  cymbalta saved me... literally."