"i have been on pristiq for 3 weeks and it is wonderful! the only side effect i have suffered is nausea, but well well worth it! i was on low dose of wellbutrin for almost a year and started suffering severe depression, my husband and 3 kids were definitely suffering from this as i was! i am very thankful for pristiq, just wish it wasn&#039;t so expensive.  i am only having to take 50mg once a day and hope to be able to get off completely soon.  there is hope!"