"i have been fighting cystic acne for years and finally decided to see a dermatologist who prescribed onexton. it took about two weeks and my cystic acne has cleared completely. i&#039;m also taking doryx daily. i had no issues with irritation from using the cream daily. i use coconut oil as a moisturizer which seems to work well. i&#039;ve been using a  mineral spf since all the other cream sunblocks seem to cause breakouts."