"i was diagnosed with anxiety and major depression just over a year ago. i am a 19 year old female and have a very difficult family situation. i first tried cipralex which made me really irritable, then i tried wellbutrin which gave me a rash. i was then on cymbalta for 6 months, but i had many side effects and was exhausted. within the first week on pristiq i began to notice a huge difference, much more energy. a month later i almost feel like my old self, lots of energy, i can control my own thoughts, and i can concentrate which is amazing because i&#039;m in university. i&#039;m so glad i finally found something that works for me, and i&#039;m looking forward to more improvements over time."