"i used this for several years with good results.  only problem was i metabolized the medicine too quickly and the third day was more painful.  my decidedly low-tech solution was to remove only 2/3 of the backing plastic the first couple days, then remove the last bit for the third day.
i take extended release morphine now and it works just as well.  it&#039;s a toss-up between wearing the giant patch and dosage issues verses remembering to take a pill every 8 hours. "