"i just started with opana er 5mg every 12 hours. the first time i used it, it did help with the pain, not much but a little. then after a few days, i started suffering from some of the side effects. anxiety attacks that verged on the near panic attack stage, difficulty breathing, and a few others. i told my doctor that i have heart problems, asthma, and a history of seizures, but he decided that he would give it to me anyway.  i am glad that opana er works for some, but it is not the one for me."