"i&#039;ve been on bactrim and aczone 7.5% for about a month now and my face is completely clear! i started noticing less breakouts the second week and by the end of the third week i had no new ones. i apply the aczone in the morning before putting on makeup and then again at night after i wash my face. i&#039;m not totally sure if it&#039;s the bactrim or the aczone that&#039;s clearing it up (maybe a combination?) but it&#039;s improved so much that even my bf mentioned that he noticed a difference this past week. i&#039;ve also experienced no major side effects. my only concern is that once i slowly start to come off the medication, will the acne come back. definitely give it a shot though if you&#039;ve been struggling with acne and don&#039;t want to resort to accutane!"