"i have had 3 major low back and neck surgeries within the past several years.  i have excruciating hip and low back pain and can never get to sleep. i wake up several times a night putting ice packs on my low back and hips. i went to see a pain doctor today, and he has put me on neurontin, gradually increasing it to 300mg 3x a day.  i have to say that it hasn&#039;t done a whole lot for me.  i woke up at 3am this morning hurting.  i am feeling highly agitated, so not sure if its the medication or just me being in pain.  i am manic depressive and take seroquel, have for years.  i am just not getting pain relief.  does it take time with neurotin to work?"