"i was prescribed roxicet 5-325 for pain relief after major abdominal surgery and i have to say this was amazing! i&#039;ve never had such complete relief from any medication before.  one tablet every 4 to 6 hours kept me completely comfortable. it made me a little sleepy, but that was fine given that i was recuperating from surgery.  it would probably not be suitable for me to take while working.  the only real side effect i experienced was a little nausea, which i learned to minimize by taking it with food.  overall, the most effective pain medication i&#039;ve ever used."