"3rd week, and i&#039;m only on 15 mg. i am very sensitive to medication. for instance, zoloft completely zonked me and all i did was sleep. i started taking viibryd at night, but didn&#039;t sleep for 3 nights. i switched to mornings and have had no trouble sleeping at night. i take it with a meal and have not had nausea, etc. i did have a terrible headache last night and believe the pain in my calves may be a side effect. my muscles in my calves feel like i&#039;ve run a marathon...very sore and tight. also, i&#039;ve been unable to &quot;stop thinking&quot; and relax. overall i think viibryd is working much better than zoloft did for me (my sexual side effects are much less than with zoloft), however i plan to call my doctor about the leg pain and racing thoughts."