"i was put on 150 mg dose about 4 weeks ago for mild depression/anxiety. i had dry mouth, headaches, spacey feeling, and nervousness. all of which added to my anxiety. i switched to 300 mg for 1 week, but the jitters increased and i could have climbed the walls! rarely felt like eating.  it did not negatively affect my ability to orgasm (like lexapro did) which was nice, but couldn&#039;t handle the side effects. trying cymbalta."