"i&#039;ve been taking wellbutrin 150 sr twice a day for 3 months now, i started with 150mg the first month and 300mg from the second month. it hasn&#039;t really helped me with depression like prozac and lexapro did. i told my doctor that i didn&#039;t want to gain weight like i did on those drugs so he prescribed me bupropion. i have more energy, i&#039;ve lost weight, but the depression is still there."