"tried most antidepressants, and i was ready to give up. i was tired of trying antidepressants, getting sick while i waited for the positives, only to find out it didn&#039;t really help.  i&#039;ve tried prozac, paxil (good but stopped working for me), zoloft (allergic to it), effexor, citalopram (worst of all).  i don&#039;t know what made me ask my doctor for cymbalta, but i did. it started working the second day i took it!  i have been slowly recovering from depression and getting my life back.  i hope the same for the people who read this.  never give up hope!"