"i have been taking minastrin for over two years now. acne was never a severe problem for me but i now only break out (usually just a few zits/pimples, nothing major) during the last week of the pack like clockwork. i did gain weight, however the time frame does coincide with my &quot;freshman 15&quot; so i don&#039;t think i can blame it entirely on this medication. it does make me a bit moody, but predictably so. this is the only birth control i&#039;ve ever tried, and honestly i only have chosen it since it&#039;s completely covered by my insurance. it works well enough (i haven&#039;t gotten pregnant) but i am thinking about switching to an iud since i am worried about drug interference and the risk of blood clotting."