"i have been on ortho tri-cyclen lo for about 9-10 years other than when i got off of it to have my 3 children.  i never had any weight gain, acne problems, and never had any heavy bleeding. i had a light period and occasional moodiness but nothing out of the ordinary.  but! i have noticed a severe lack of sex drive!!  as in no sex drive at all, nothing, notta, zero, zilch!!  this is a great pill to take if you don&#039;t care to have a sex life and are not married."