"i have had depression from age 12 and am now 40. i have used all ssri&#039;s, welbutrin, effexor, etc., but would have to quit each one due to various side effects. buspar &amp; xanax helped but weren&#039;t strong enough. i was fed up! so i quit all depression medicines for 3yrs (not advisable!). i became more depressed than i had ever been in my life. i went back to a doctor and he put me on viibryd. i was sceptical! but he explained how it was different. so i tried it. i used the gradual dose increase and i had bad nausea but it did eventually pass as long as i took it with a high protein breakfast. that was my only side effect. i have been on it for over a year and have never felt this well! i do get withdrawal symptoms if i miss a dose but to me it&#039;s still worth it!"