"i&#039;ve been on depo since i was 15 years old . . i am now 33 years old . . i first got on depo because i had really bad cyst on my ovaries and breast . . with depo it has controlled the pain and size of cyst . . i&#039;ve gained maybe 5 pounds since i&#039;ve been in this . . no bleeding no spotting what so ever !!! i do get lower cramping once in awhile but it is tolerable . . i also do not plan on having kiddos so this was the best choice for me :)"