"at first, it was horrible. i felt like i was dying every time i would take it before bed, i felt as if i were to fall asleep i&#039;d never wake up. this lasted 2 weeks maybe a month.... my body eventually adjusted to it, the voices went away. slowly, but surely. i was also in a serious state of depression, and it takes some time but now after a little over a year of taking it, being bipolar and having countless manic and depressive episodes, seroquel has saved my life. i&#039;ve never felt like myself like i do right now in such a long time. the only dumbs down is you have to seriously monitor your weight on this thing, the pounds just pile up if you don&#039;t watch your weight carefully.."