"i am a 19 year old female. i have been using pristiq for over 3 weeks now. the first couple of days were pretty intense for me, i was very jittery, had a constant feeling of a ball being in the back of my throat, and was constantly thirsty. my second week was great, i started seeing very positive results. pristiq really suppresses my appetite, but i&#039;ve only lost a couple of pounds. constipation is also another thing to be prepared for. i take it in the morning and it boosts my mood. i am also taking clonazapem for the night time. i would recommend this medication for people with mood disorders, but you have to be patient to see results. the first couple of days might frighten you a little, but be patient and see how you feel after a couple of weeks."