"was using butrans 20 dose.  chronic joint pain since childhood.  was using  hyrdocodone and gabapentin.  patch was amazing at controlling pain from day 1.  lost 5 lbs due to stomach uneasiness, loss of appetite.  i had no marks at patch sites.  at 7 weeks every spot where a patch had been used erupted in blisters.  it was very odd and now 2 weeks later the red spots are finally receding.  pain control 100%, stomach and bowel issues manageable.  "