"i started taking this about five years ago for anxiety/ocd/extreme irritability (bipolar spectrum) and it is a great mood stabilizer. however, it seems all great remedies have their side effects. for me (40-something female) that meant some hair loss and memory issues. also, i&#039;ve noticed that if i miss even one dose (i take 150 mg twice a day) i start to get really agitated and irritable, so i&#039;m afraid that it&#039;s permanently altered my biochemistry - guess i&#039;m stuck with it. i still think i&#039;m better off than the fat zombie most women become on antidepressants."