"i was put on desogen after continuous bleeding on ortho tri lo. my practitioner thought i needed higher hormones. desogen stopped all the spotting but it killed my sex drive. even when i did have any sexual desire i didn&#039;t get the physical affects of arousal like lubrication. it made sex completely unfun even on the rare occasion that i wanted to do it at all. i gained weight while on it but i started it pretty young and i know weight gain is pretty common around that time."