"diagnosed adhd, bipolar, major depression, gad, panic disorder. have been on saphris 5 mg at night for 1 week. after the first dose i could tell a huge difference in my mood. for the first time in months i woke up in a great mood. after a few days, i knew i was no longer in mania. which i&#039;ve been in for at least 4 mths. my thinking is back to normal. the only problem i&#039;m having is keeping my mood stabilized. when i take it at night it puts me to sleep in 15 min. no longer using sleeping meds. for one week of use i think it&#039;s a great medicine."