"i have been on saxenda for 5 weeks now . i have lost 15 pounds. i take my injections at 7pm every night. i wanted to avoid the side effects by taking it at night. the nausea has been really bad for the past week, since i have been on 3mg. zofran has helped. i find i do have to take a laxative to aid with the constipation. i&#039;m happy it is working . a long journey ahead."