"i am a chronic pain patient and have tried dozens of medications for my pain. opana works wonders through an iv when i&#039;m in excruciating pain, but the oral pills just don&#039;t help as much. my pain doctor switched me from oxycodone 4 times a day to opana 3 times a day and it didn&#039;t touch my pain. i did some research and it only absorbs 10% orally. it&#039;s good as an iv or injection medication but not as much as an oral pill"