"i have had depression for years with obsessive compulsive disorder. i have been been on everything from xanax, effexor, depakote, prozac, zoloft, etc. i started viibryd 4 days ago along with adhd medicines and anxiety meds and i have to say my brain is not running 90 to nothing i am not depressed and feel good. yes my gi system has been upset and last two nights i have not slept well and i have had a mild headache but because everything is manageable and i mental feel better i am willing to tough it out and hopefully it will stop. doctor gave me a free starter kit starting with 10mgs for 7 days then 20mgs for 7 days and 40mgs for 7 days so hopefully it will keep going this good or better."