"when the doctor gave me these patches i had a a &quot;yeah right&quot; attitude.  i am  stunned! i applied the first patch and 3 days later i had significant pain relief! i just applied my 2nd patch and i am able to resume doing a lot of things i haven&#039;t done in years. i had side effects at first, sleepiness, shakiness, and severe nausea but they passed within the first week. i am amazed and pleased at the effectiveness of these patches."