"i started taking saphris 10 mg at bedtime 2 months ago and i have never taken a medicine that is so powerful but without the horrific side effects of it.  my mother and i take care of 6 children and so i have a bunch of different personalities that are around me each and every day. when i started taking this medicine it took a great deal of heaviness i was carrying around with me off and that is exactly what i needed. the only side effect it gave me was the bitterness as it dissolves under your tongue, but that is well worth it for me.  i am on depakote as well, i started saphris about a month ago. i am getting off of depakote and staying on saphris - it is a miracle."