"my original intent with topamax was never weight loss, (mood) nor would have i ever believed the results i&#039;ve obtained 19 months later. quick negatives-my mental agility decreased significantly, i misspell my own name; most food &amp; beverages taste like rubbish; and, the generic version is subpar. i was always overweight, i&#039;m mid-30s, male, &amp; slimmed from 275 to low 180s, size 42 to 32, xxl to l. it stays off! still drop a few lbs. every month. however it&#039;s impossible for me to get off, i tried once and i went into a severe depression, but i&#039;m a healthy weight now with perfect blood pressure."