"i did very well during the free trial lower dose period. i lost 12 pounds. ive been on the drug for atotal of 5 weeks and have not lost any additional weight on the scale.  i have lost inches. 4 around my waist 3 at hips and 2 on each extremity(i must be gaining muscle).  plus im feeling better and keeping track of all food a fluid im eating and drinking. i stick to a 1200-1800 calorie diet. so my body doesn&#039;t get bored(most days 1500).  i do have numbness in my toes but thats it.  my starting weight was 245lbs. im female and 42."