"i&#039;m going through peri-menopause at 46 and have put on 25lbs over the past few years. no amount of diet or exercise could help me lose this extra weight. i exercise each day just to not gain any more weight. seeing that i was struggling with this issue, my dr. prescribed qysmia. first few weeks, i did feel a little tired and foggy, but got through it. on 7.5 mg now and have lost 9 lbs in 19 days. my appetite has been squashed like i never expected! when i eat a meal, i cannot finish all on my plate because i feel full very quickly. i still have a half glass of red wine at night though. no desire for sweets or carbs."