"been taking concerta xl for a while with a steady titration from 18mg up to 81mg. i take it around 9am each morning and the first few hours are very restless. however by early noon say 1-2pm i go into a slow sometimes dragging comedown which makes me sleepy and therefore having a knap during the day. this leads to an almost sleepless night which can upset my brain in many ways.

positives:

alert, talkative, sociable and above all concentrate.

negatives:

jaw clenching (gurning), sweaty, sleepless night (because of the midday knap)

all in all i have tried alteting dosage times in the morning and i can quite easily eat without feeling nausea. weight loss is noticable but at a good stable rate. many people have to give concerta a chance."