"i have tried everything under the sun for depression and anxiety over the past 15 years. saphris is an amazing medicine. i take the black cherry flavor, which does not taste horrible, but is good (other flavor does taste horrible though) and i feel like my depression has been majorly lifted, my manic episodes and irritability have decreased greatly, and i am doing things in life that are productive for the 1st time in years and years. i must say i must also take lamictal though, as without that the mania goes out of control even with saphris. but together, excellent combination."