"i&#039;ve been on trintellix for 7 weeks along with buspirone for anxiety, which is my biggest problem. about 1 month in on trintellix i got hives and itchy skin too.  wasn&#039;t sure what that was about.  the hives seem to be going away slowly, not all gone yet but the itchy skin remains.  it&#039;s manageable, just annoying.  not really sure this medication is helping me.  right now just trying to get/keep the anxiety under control."