"of the non-benzodiazepeine anti-anxiety agents, vistaril is my first choice. vistaril seperates itself from the others by rapidly inducing a pleasant &amp; warm feeling. by comparison, things like compazine and clonidine are much colder and more harsh in side effects. although vistaril is gentle &amp; easy going for the first hour or so, a strong drowsiness will come on by hour #2. but overall i&#039;d still rank it as a side-effect-free type of medicine, when compared to other non-benzo anxiolytics."