"zaldiar- 37.5 mg tramadol/ 325mg paracetamol -tablets were prescribed to me every 4-6 hours for chronic pain following a severe leg infection and ulceration that wouldn&#039;t heal. i tried other over the counter pills including paracetamol, but couldn&#039;t sleep at night or concentrate on anything with the pain. zaldiar has been great - provided you don&#039;t forget to take it. if you do the pain comes back very quickly. side effects so far - very dry, horrible tasting mouth, loss of appetite (a good thing) and feel a little confused at times and forgetful (maybe that&#039;s just age) and a little nausea. feel so much better now pain is under control - thanks to those who invented tramadol."