"i&#039;ve been on this drug for about 3 months at 10 mg. the first 2 weeks or so i had morning gas. i usually don&#039;t experience physical start up effects like others do. trintellix has helped with social anxiety. it&#039;s more gentle drug. trintellix however, made my anhedonia much much worse and my sex drive has become non existent. i&#039;m freaking castrated now (on 20 mg its a lot worse). for these reasons i decided to stop taking it. :("