"i am a first time user: extreme fatigue for the first few days taking it. after a few weeks of dramatic mood swings, the nausea around period week woke me up in the middle of the night! waves of nausea that didn&#039;t allow me to eat for almost entire day. but, i&#039;m still sticking it out- no weight gain, i&#039;ve started taking b-complex which really helps. oddest side effect is i no longer have desires for coffee (it makes me more tired) but am now frequently very thirsty."