"i&#039;ve been on the depo shot for years and decided to change to the skyla. since i haven&#039;t had a period in a few years the dr decided to go ahead and put the skyla in. it was extremely painful guess due to the fact that i wasn&#039;t on my period when your cervix opens slightly. the dr had to give me an injection inside down there to open my cervix slightly but it was extremely painful. i recommend that if your on depo and want skyla, wait till you have your period."