"i have been on several medications (citalopram) &amp; after 6   years it simply stopped helping my anxiety. it made me tired, foggy &amp; spacey anyways. i had a hard time being sharp at my corporate job. i then got off of anything and was just ok for 7 months. then my spouse almost died and it sent me reeling into depression &amp; severe anxiety. i was paralyzed with fear. i couldn&#039;t get my work done, cried all the time, had major anxiety. i was afraid to try anything due to the fear of being tired, foggy or dull. started 30mg cymbalta. it helped me within 3 days. first 3 days was nauseous. after 2 weeks i was no longer depressed, no catastrophic thinking or panic attacks. wish i had tried 10-20 years ago! it has turned me around. not foggy or tired!"