"i was on orsythia for about a year. it did its job in that i did not get pregnant, but i had to quit taking it because of the awful side effects. weight gain was minimal but definitely occurred. after about 6 months my acne became worse than it has ever been, but even that wasn&#039;t the worst of it. orsythia brought my anxiety to an all-time high, and i was experiencing awful mood swings. all of these symptoms practically disappeared within 2 months after quitting it. i did not have anxiety before taking orsythia, and now even though it has been almost a year since i quit (haven&#039;t taken another birth control since) i still have bouts of anxiety from time to time. i believe my anxiety was triggered by this birth control."