"i have severe menstrual pain, so bad to where i throw up,and i am in bed for the whole day. so i decided to get on the pill. my doctor prescribed me orsythia and it changed my mood severely. i was very mean and grumpy all the time, it felt like was on edge all the time. which is not like me at all, i am a very easy going, go with the flow, never really get mad type of person. it did not help my cramps as much as i thought it was going to. it also made me have really bad head aches and  acne. it has been almost a week since i&#039;ve stopped taking it and my mood and acne has cleared up. the only thing now that i&#039;ve noticed is that my knees and  ankles ache, after coming off of the medication. but i&#039;m sure that will clear up soon."