"took about a week to get over the side effects - still get some morning grogginess, but a strong coffee and ten minutes of mindful meditation or exercise sorts that out completely. unlike others who have left reviews i&#039;m only on 15mg - but the effect has still been amazing. i&#039;ve had problems with depression and anxiety since i was 16 and had tried a couple of ssri&#039;s that didn&#039;t help. prior to taking it i had been having issues with sleep, trying to adjust without an alcohol and cannabis dependency. mirtazapine certainly helped with sleep, though it still took a while to nod off, when i did i would sleep for hours and better than i have in years. by sorting out my sleep, managing my depression became a possibility - it&#039;s changed my life."