"i have been on viibryd for about 8 months now. in the past, i have been on zoloft, effexor, and pristiq. the pristiq seemed to work okay for a while, then it seemed to slowly stop working, so my psychiatrist recommended trying viibryd since it has an added built-in benefit similar to abilify&#039;s low-dose impact when administered with an anti-depressant. i think the worst part about changing medications is coming off of older antidepressants. with viibryd, the added &quot;spark&quot; appeared during week 2 (20 mg). i have never felt better in my life. anxiety ran high for the first couple of weeks, but that was the only side-effect and it was short-lived. additionally, zero sexual side effects."