"i started taking bupropion hcl 150mg about 3 weeks ago at the same time i quit useing zoloft 100mg, going off of zoloft was the hardest thing for me, it was hell, but i hung in there, today i am really happy that i&#039;m off of it, and the bupropion at 300mg a day is excellent for me, no depression, sex drive back fully, it took about a week to adjust to, but i love it now, my mood is balanced to the level up to good mood too, so far no bad mood, no longer a zombie on zoloft, yay for me. just a tip for going off of zoloft, it gets bad, but in a few weeks it clears up, i almost gave up, but i&#039;m glad i didn&#039;t, again i feel alive , :)"