"i was on latuda for 3 weeks and it was horrible. where to begin. from day 2 i was unable to sleep at all. i averaged 2 hours of sleep for 3 weeks straight! fortunately my bipolar 1 and schizoaffective disorder were held in check. i don&#039;t know how. my sleep has now come back due to 100mg of seroquel. albeit i can not fall asleep without it. the worst lingering side effect has been with my tongue. it is constantly pushed up against the roof of my mouth! it never ends. i also constantly grind and clench my teeth. this has been the worst experience with any medication i have been on. i am also on 900mg of lithium and 300mg of lamictal."