"i have had si on and off since i could remember. this changed my life. i&#039;ve only had a suicidal thought once or twice in the last 8 months of treatment. i&#039;ve had a lot of stressful situations pop up during this time and i am thrilled with how well i was able to manage. only on 100mg once daily was with 60mg duloxetine and 150 bupropion. i wish i didn&#039;t waste all these years struggling. why wasn&#039;t this in my life 15 years ago?"