"i am bipolar type i and was switched to saphris from seroquel by my psychiatrist.  one dose and i began having suicidal ideation that i hadn&#039;t experienced in years. i had the presence of mind to call my psych doc immediately (it was a weekend) but she didn&#039;t call back.  i am a nurse and should have known better, but i took it the next day.  after the second dose, i was frightened i would act on the impulse.  luckily i have a very supportive and observant husband.  i called doc again and she said to stop immediately, of course, as i should have after the first dose.  i saw her on monday and went back to seroquel.  less severe side effects included numbness of my entire tongue and sick-feeling somnolence."