"have been on seroquel for 4 weeks for depression. i take it before bed. still experiencing a &quot;hangover&quot; type feeling in the mornings. i gained 8 pounds in the first 3 weeks i took. makes me want to eat even when i am not hungry.  however, i am not crying as much, can handle day-to-day life better, and i haven&#039;t had chest pain or racing heart beats since i started, which is a great improvement. "