"horrible side effects! i tried ciprelex (escitalopram), but made me so tried all the time. my doc switched me to pristiq (desvenlafaxine), i had 0 side effects, but i couldn&#039;t afford the $105 price each month without a generic brand or drug plan. doc switched me to effexor claiming it was &quot;very similar to pristiq, and available in a generic&quot; however i had the worst insomnia at night. trouble falling and staying asleep at night- would wake up every hour with mind racing. dry mouth throughout the day no matter how much water i drank. also, very fidgety feet and legs while sitting or laying in bed. i was exhausted all day everyday, yet continued waking up several times throughout the night. went back to my doc, and switched back to pristiq."