"this drug gave me bad reaction from the very first dose. my doctor thinks i had serotonin syndrome from taking this with an antidepressant. i got a fast heart rate, flushed face, restless, like taking some kind of stimulant. they cut my antidepressant dose in half which helped some but i still couldn&#039;t stand the side effects. lots of nausea too. pain relief was ok but not great."