"have only been on pristiq less than 1 week and previously taking lexapro, which did nothing for me. on lexapro for years and accepted it when doctors told me that i may not feel better than what i do. with pristiq someone has turned the light on in my brain and there is a distinct shift in my mood. i hope i have found the right antidepressant to help me recover and feel like entering the land of the living again...fingers and toes crossed. i will keep you posted...no noticeable side effects as yet."