"my doctor tried me on this when it first came out. i&#039;m unusually sensitive to medications so we started at 5mg/day. it worked great for about a week. side effects of nausea, blurry vision,dizziness and itching were bothersome but manageable. we then upped it to 10mg a day. again, it worked for about a week and then stopped. the nausea was horrible. i was taking it at bedtime with a small snack and zofran (for nausea) and it still made me sick. i would wake up nauseous &amp; to my feet/ankles itching intensely. benedryl or other allergy meds would not help. it would last about an hour and then go away...until the next morning. had to stop after 2 months from the horrible side effects. by that time it had no effect on the depression whatsoever."