"my doctor started me on a very low dose of this (100mg). i have anxiety, depression, and (a questionable diagnosis, pending review) of bipolar disorder. the first day i took this i had a full blown panic attack. my heart was racing so fast and i was experiencing pretty bad chest pain and heaviness, so much so that i called the office and they wanted me to stop taking it and go to the er to have an ekg done. i stopped taking it for about 2 weeks, but wasn&#039;t ready to give up on it - big mistake. so i went back on it for 3 days. each day i had elevated heart rate, and felt anxious all day long. i was extremely irritable to the point of rage, my entire face broke out with painful cystic acne i&#039;d never had before - basically over night. skip!"