"i found the medication very helpful with only some nausea lasting a few days but constipation that continued. it was very calming and helped my sleep. then after about 2 months i began to get pain in all of my joints especially any joint that i may have injured in the past. i was unable to get through a work out at the gym and that is the best treatment for me. the day that i opened a tube of toothpaste and wrenched  the joint in my thumb was when i had to say enough. it has taken now over 3 months to regain my range of motion and to be mostly without pain caused by this medication. after reading the other review about joint pain i felt i should also comment about my experience."