"i was first prescribed pristiq and found it to seriously affect my interest in sex.  i was then switched to wellbutrin.  i have been on this medication for 2 months now.  at first i had severe headaches and almost gave up.  i&#039;m glad i didn&#039;t because i am feeling much better.  i do find it hard to sleep some nights but hopefully that too will pass.  i also feel nausea occasionally.  my moods seems much better, negative thoughts creep up but quickly go away and i feel more content.  i am currently on 150 mg."