"i&#039;ve been on trinessa for a year now. i went to the doctor because i had horrible cramps. the pain from the cramps made me vomit and have diarrhea. in the first 2 months or so of starting trinessa i had spotting. after this it was gone. my period came every 31 days or so (which was how it was before birth control) for 6 months. after six months on being on trinessa my period regulated to exactly every 28 days. triness has definitely made my period cramps lighter, which is great. i just take two aleve before and during my period and i feel better. i have not gained any weight from it. but i have noticed my sex drive is way lower. if you take two pills at once because you missed one, be careful! you may get nausea."