"my nurse practioner kept insisting i try prozac along with olanzapine for my severe bipolar depression because it was the gold standard (supposedly they work good together). so, i ended up taking prozac all the way up to 60 mg for over 12 weeks (along with carbamazepine, olanzapine &amp; now saphris) and i only got a partial response to the medicine. it helped get me functioning again but i wasnt happy. i still didnt enjoy the things i loved doing. for example, i would try listening to music or play video games but it wouldnt do anything for me. the euphoria was kind of missing. i know 80 mg is the max dosage but i shouldnt have to be on the max dosage or go beyond it to get a desired effect. oh, and i lost my sex drive on prozac too! grr!"