"a word of caution to anyone with a history of depression or anxiety. i experienced some really scary side effects in the three weeks i tried qsymia, including suicidal thoughts. i have a history of mild anxiety and depression and i experienced very severe symptoms while on the drug including panic attacks, restlessness, trouble sleeping and extreme sadness. i&#039;m tapering off the med now. i have a bmi of 35 and a history of pcos which is why my doctor prescribed it, but she should not have given me this with my history of depression without a more serious warning of the potentially scary side effects. good luck to all of you who are trying and who it&#039;s working for."