"i&#039;m in my mid-40&#039;s and have been on zoloft for six years. anxiety gone...it no longer rules my life. i am able to go out in public and not feel like my world was going to end. still am subject to turning inward at times..but doesn&#039;t everybody? i do notice some memory issues like really having to think longer about names and places. (sometimes i feel like a slow computer trying to load a page!) dosage has been 150mg."