"after suffering from severe depression and ptsd; and having been prescribed luvox, wellbutrin, paxil, zoloft, and combinations for over 20 years; i read about modafinil being used off label. the only antidepressant that had helped previously was the zoloft. after several years; it lost the effectiveness from when i first began taking it. in the meantime, i became permanently disabled due to many physical conditions along with my mental conditions. my doctor added modafinil to my daily regiment of medications. i can think more clearly; and don&#039;t lose my train of thought, nor become distracted as often before taking modafinil. it has been a blessing for me and i have not experienced any ill side effects."