"i guess i have had major depression my whole life and i have taken a pill here and there, but i never stuck with it.  recently with the passing of my mother, i guess emotionally i hit rock bottom and decided i needed to look at doing something and sticking with it. pristiq was the second medication my doctor put me on, and i am at week three and i am amazed.  it came to late to salvage my current relationship, but my partner says, that i am a different person and asks if it is real.  it is real, i feel like i did when i used to be happy, when was that?  years ago, i am thinking more clearly.  i am still grieving for the newly loss of my mother and my relationship at the same time, but my mind is &quot;clear&quot; and i am singing in the shower."