"been taking 100mg of zoloft for about 5 weeks now to treat depression and general anxiety with what also may be a touch of obsessive compulsive disorder.  i have to say the results were better than expected.  i may have experienced a placebo effect within the first week when things seemed magically better but by the second week the anxiety and depression hit again.  by weeks and 3 &amp; 4 it began leveling off and i now feel more balanced emotionally.  my mind isn&#039;t spending time fixating on things outside of my control and things have been looking up even though my personal situation has not improved all that much."