"i take 0.25mg whenever i feel anxious with some propranolol to calm down my heart rate (sometimes feeling my heart beat fast can cause anxiety), and it usually does the trick. i&#039;m switching to 0.5mg in hopes that i can just take one 0.5mg pill without the propranolol. just so you know, the half-life of this medication is 18-50 hours, meaning you&#039;ll feel some of the effects for that long, which is really nice when you have a stressful few days."