"everyone reacts differently.  i tried trazodone twice - most recently for the past month to help out with insomnia issues.  dosage was 25mg, temporarily raised to 50mg, then back down to 25mg.  it is not a drug that i found to have a powerful noticeable effect - it sort of acts in the background and when you drift off to sleep it aided that for me.  my problem was that at some point in the early am i would awaken (2:30 or 3:00) and feel terrible with anxiety.  after a couple of weeks i also sensed a gloomier/dark mood and eventually had to stop taking it.  one random side effect - chapped lips and skin below my nose.  it works for many, just not for me.  one positive effect - seemed to assist with constipation issues."