"i have muscle stiffness &amp; pain at the base of my neck &amp; head, which over time caused migraines &amp; tension headaches. botox &amp; lidocaine injections have relieved the head pain. my doctor is still working on trigger points for the pain in a few sm areas of the upper neck. he prescribed celebrex after ibruprofen (did nothing) &amp; mobic (helped some). celebrex helps the most. i believe it&#039;s bc mobic is a selective cox2 inhibitor and the celebrex is only cox2. it brings my pain down to between a 0-2, depending on whether i&#039;m experiencing 24-hour soreness from the injections (2) or if it&#039;s just acting up from activites like yardwork or working too long at the computer (0). i&#039;ve only been taking it for a month &amp; good so far."