"let me just say that i had back surgery 9 years ago in addition to have 2 discs replaced and my spine fused. and 5 years ago i had a spinal cord stim implant. i&#039;ve taken every known pain med out there and the last combination of medicines i tried nuycnta 100mg and opana. which these 2 combined worked to alleviate 60% of the pain. i was still working while on these meds. i stumbled on something that worked for me and i swear by it. i know people that have lupus, cancer, and ms that now use it instead of all the other pain meds out there. good luck!"