"i was put on depakote er and celexa for depression and anxiety.  my mood and depression were helped and it knocked out my migraine headaches completely.  i experienced so many horrible side effects though. i gained 50 pounds in the six months i was on this, i lost my hair, i developed tremors that have not completely subsided, i had horrible stomach problems, heartburn, it made me extremely lethargic, libido was gone. this was just my experience with depakote and if it weren&#039;t for all of the side effects i would have stayed on this medication.  hope this helps."