"i started cymbalta for major depression and suicidal ideation (no plan).  it worked.  took as much as 90mg at my high point.  i&quot;m now tapering down to 30 mg.  going from 3 pills a day to 1 pill a week is hard but manageable.  but the side effects for this drug are real.  dizziness, blurry vision, constipation to runs.  i would say for me, i could work through them because i wanted to live.  the tapering has started aura migraines which are close to unbearable but i get through it.  i say close because i almost felt like going to the er once.  i&#039;ve slept 2 days straight trying to overcome an aura migraine.  no light, sound, food, or blankets.  if you were in my place over a year ago, taking cymbalta would have been a no brainer."