"give this medication time to work. i have been suffering with acne since i was 12 years old, and i am 39 now. i started spironolactone 8 weeks ago. i would say that the bumpiness in my skin improved within the first week. but the breakout during the 2nd week and the residual mess during week 3 had me wearing turtlenecks. but after that, i saw nothing but improvement. less and less acne, skin smoothing out, less oiliness. now i am about 95% clear and i only expect it to get even better!"