"i started taking contrave for menopausal weight gain. i srtated it 1 week before my fiance left me for a millionairess.  not sure if it was depression or contrave (likely a combination), but i lost almost 30 pounds in a month.  now it&#039;s been 6 months, and i&#039;m down 34 pounds.  i was vomiting the first week, but that went away quickly.  only other side effect is slight muscle twitching.  i was barely overweight, but no diet or exercise would take the excess weight off.  i&#039;m thankful."