"i began taking cymbalta 30 mg on 07-07-16 due to moderately severe depression, anxiety and physical pain. almost immediately i felt better in all aspects; however, severe chronic constipation also occurred. i took miralax daily and still only had bms every two to three days. then about two to three weeks ago i started feeling angry as if i was backsliding. i was going to increase from 30 mg to 60 mg but my doctor wanted to prescribe a medication for idiopathic constipation, which mine wasn&#039;t. my last dose of cymbalta was on 09/30/16 and i started taking zoloft 50 mg again on 10/1/16.  i guess one can&#039;t have it all. even taking zoloft causes constipation but i take 20 billion probiotic twice daily and it moves things along regularly."