"i have suffered really sore muscles as the patch wears off. my neck feels like i have whiplash and my upper back and shoulders feel stiff and hurt. i&#039;m always well aware when it&#039;s time to change the patch. the problem is that the muscle pain starts to get really bad on the 5th day. because of the 4 patch per month limit, i have to wait. vicodin makes me feel loopy and tramadol makes me feel completely out of it. i will be speaking with my doctor to see what he recommends i do. i, too have rashes at the patch site as mentioned by many others and the itching can get quite embarrassing as i don&#039;t realize i&#039;m standing at the meat counter at the grocery store scratching my belly until someone starts to stare. "