"i have to say this is a great medicine for people to try especially if those having difficulty sleeping.  i had mania and my highs and lows have become stable.  i have been taking this for about a month and noticed a difference the next day.  it does have an awful taste but it is worth the benefits.  my cocktail currently for bipolar 1 is effexor xr, depakote, lamictal, and saphris.  i plan to ween off some of these medicines since saphris has been working well.  i have tried abilify and seroquel and had bad reactions."