"i was on zoloft for about 3 years when i was a teenager. it tremendously helped my depression. there were side effects however. my doctor told me that it metabolized slowly and takes a few weeks to notice results.. so in my ignorance, i thought that that&#039;s how long it takes the body to metabolize the stuff. for at least a year there would frequently be times where i&#039;d forget to take my pill in the morning.. sometimes for a few days in a row. so when i remembered that i should take it, i would take 2,3, or even 4 of them to make up for days where i skipped. like i said, this is only due to my own stupidity. i would end up being awake all night long.. completely stung out and not knowing why. i developed insomnia and pretty much went crazy."