"im on around the clock opiate therapy, so when i have something major come up, like a kidney stone, i have a hard time finding a medicine, then being able to take and mix it with my current medications.i had a kidney stone about 6 months ago, and the urologist gave me 60, 4mg hydromorphone tablets; they were useless, i took them back, he didn&#039;t want them, so i flushed them down the toilet.he prescribed demerol 50mg 1 or 2 tabs every 4 hours, and it worked like a charm. i will say, when i went to the er for the kidney stone, the iv dilaudid worked wanders, but taking it by mouth was absolutely a waste, not to mention the money i spent, getting the prescription filled, to literally flush it down the toilet. no good orally, for my pain."