"i took for 8 weeks, 53 year old male. i moved to a new town for job. it is pretty depressing when you don&#039;t know anyone. zoloft 50 mg. first night no sleep. started taking  at night with ambien. i sleep for about 5 hours then i&#039;m up at 3 am. major side effects: inability to orgasm, clenched teeth, restless legs, trembling, loss of appetite, diarhea and sweating. first week was nausea, trembling but emotions were better. after 8 weeks, i think the side effects aren&#039;t worth the benefit. quit cold turkey 4 days now. no major problems. teeth clench still but, not as bad."