"have used it off and on for 2 years now. it works wonderfully, and improvement is usually shown immediately. however, it affects my blood sugar immensely and i usually have to quit taking it. if i don&#039;t eat constantly i get very sick and shaky because of low blood sugar and because i have to eat constantly i gain weight. the medicine itself works great, it would just be nice to not have to sacrifice feeling well physically for mentally."