"was given a prescription to pristiq to help with adhd in addition to xanax for anxiety.  the first day i noticed an improved mood, but initially thought it was the xanax.  after taking pristiq first thing in the morning and holding off on the xanax, i noticed a significant improvement in mood over no medication, and a slight improvement over taking both pristiq and xanax.  between the two of them, they seem to keep my anxiety and focus in a healthy range.  the only side effect i&#039;ve noticed is slight jaw fatigue from clenching.  pretty minor though, and something i have no problem dealing with."