"i&#039;m 17 and have been taking 18mg concerta every day for a week and a half. this is the second medication i&#039;ve tried after being diagnosed with adhd (i was also diagnosed with major depression). first i tried adderall, and while it made me feel very alert and productive, i could not handle the severe depressed feelings from the comedown. so far concerta has made me feel productive and positive for about 3 hours, and then depression slowly creeps in and gets progressively worse for about 8 more hours. it&#039;s not as intense as the depression from adderall (which even led to suicidal thoughts), but it lasts longer. i also become irritable, anxious, and tired. i&#039;ve also lost weight because trying to eat makes me feel queasy."