"i had been on generic lexapro 10mg for about 18 months and it treated my depression well, but i gained almost 40 pounds, was a bit sleepy, and was experiencing sexual side effects.  i was scared to try something else but the weight gain was just too much, especially since it seemed to continue.  my doctor gave me trintellix 10mg samples which i&#039;ve taken for a month and what a difference!  i no longer feel sleepy all of the time and the difficulty in achieving orgasm is gone.  as for the weight issue, i&#039;ll have to see if it helps.  i feel much more &quot;normal&quot; than on lexapro as far as energy and mental focus.  the only downside is i do feel more anxious and have more nervous energy, so i don&#039;t know how well this drug would treat anxiety."