"i started tenuate in mid march and now am down 40  lbs. i use tenuate along with a low calorie diet and moderate exercise.  i just reached one of my first goals which was to be &lt;200 lbs.  that was a big step for me.  i haven&#039;t been this small since my first pregnancy back in 1995.  i still have a long way to go but i am very happy with the outcome this far.  i usually skip the tenuate on the weekends because i tend to not eat breakfast on weekends.  if i don&#039;t eat an hour or so after taking the pill in the mornings, i get a little jittery. i would recommend this to anyone looking to lose big numbers. i weigh in with my doctor once a month and she monitors my blood pressure, etc. couldn&#039;t be happier."