"saphris has helped me more than any other medication (which were many, many over 12 years). i was blown away by the benefit and bewildered that it took so long for someone to prescribe it. i still don&#039;t have the strength and energy that i need but i am functioning at 80% to 90%. before it was barely hanging on with suicidal periods. savella was another good medication for me but not quite this good. the racing thoughts, paranoia, and insomnia are gone. i usually fall asleep within 15 minutes of lying down. although i am having some nights of waking up after 3 hours. just getting to sleep earlier and getting the required sleep i need has made a tremendous difference in how i function and cope. my side effect has been arthritis and weight gain."