"i have been on wellbutrin xl for a little over a year, and it has dramatically improved my quality of life. i have struggled with depression for almost my entire life, and only recently sought out treatment, and wow, what a difference! wellbutrin didn&#039;t cause any weight gain - if anything i lost some weight - and it didn&#039;t decrease my sex drive. it took about a month for it to kick in, but it was well worth it."