"i have had absolutely no problems with tri-sprintec.  i don&#039;t have any side effects at all.  no weight gain, no mood swings, no depression, no anxiety, no nausea, same sex drive.  (no increase in breast size either - i wish i had that side effect!)   i feel exactly the same taking this as i did not taking any birth control.  the only difference is my periods are lighter and shorter, and my cramps are no longer severe.  by the way, i was really scared to take this because of the negative reviews i read!  but before you decide this is a bad pill, give it a try.  every woman&#039;s body is different and your experience will just depend on your body!"