"i was on deposit-provera for 23 years and my md decided i needed to come off of it and placed nexplanon in my arm. i would have just had tubes tied except i have pcos and need the hormones to control cysts. it was placed in october 2014 and periods started july 2015 and have been relentless since occurring 7-9 days every other week and i also have pmdd and the change almost made me end up in psych ward. i became extremely depressed and wanted to get away from everybody and everything so my md started me on estradiol in addition yo zoloft i take already for pmdd. this was slightly helpful but not much and mood swings and depression did not calm down until i put myself on estroven and relacore to help stabilize my pmdd. periods are painful."