"on 20mg for about two months with no concrete signs of improving depression/anxiety. dr. told me to just stop taking it as i hadn&#039;t been on it very long so didn&#039;t need to taper off. after not taking any dose for 3 days, i woke up in middle of night with excruciating stomach pain and vomited off and on for hours. absolutely horrible. i also think there could be a negative interaction between this drug and concerta. just my own personal experience. i hope this drug works for you! if not, there&#039;s are hundreds others that will."