"in 2012 i was about 225 pounds, i had high blood pressure but i think that was brought on by ra(since 2007), i finally asked my doctor, the new endocrinologist at the local medical group who diagnosed my hypothyroidism too. if she could prescribe something to help me. i started 12/19/2012 and with diet, exercise and phentermine i went from 217 to 155 (62 pounds) by 11/30/13. it was work, but phentermine cut my appetite to zero and boosted my energy to 10. i never felt sick and as long as you don&#039;t take it after like noon you won&#039;t have sleep issues."