"i had to go onto oxycodone as i became allergic to buprenorphine patches &amp; reached the limit of how much morphine i could tolerate.  with oxycodone my pain relief is better than morphine, the migraines are still a problem but less &#039;sharp&#039; than when i took morphine.
as i live in england i am able to take oxycodone as an extended release drug called &#039;targinact&#039;.  it is a combination of oxycodone but also naloxone, which elimintes the biggest problem with opiates.....constipation.  targinact works amazingly well - i can take oxycodone in high doses but with no constipation.  it is a shame that it isn&#039;t available in the us.  although it is more expensive than oxycodone, all my prescriptions are free thanks to our wonderful healthcare system."