"i have been on this for one month. i have progressed up in dosage very quickly due to my lack of control over my depression. i started at 30 mg per day and since my doctor participates in clinical trials, he&#039;s aware of how far he can progress with this medication. i am now on 120mg per day, just after a month. it&#039;s given me more energy, less appetite, no weight gain. i feel like i can live my life and cope. i temporarily taking it with klonopin, but hope to be just on cymbalta soon."