"i have been having depression for about 10 years. it took a long time to get the right one. eventually i was put on effexor xr. started from 37.5 then finally 300mg per day. effexor gave me a lot of side effects but i found it to be very good making me feel myself again. there was only one major problem, i got addicted to gambling even from the day i started with 37.5. i was in major dept. i am now trying other medicines (seroquel) but i am not the same anymore, very lazy, no motivation. since i have stopped effexor i have stopped gambling. and as for the depression, i am on trial with seroquel. wish me luck!!"