"i&#039;ve been on trintellix for 6 months and this pill has been a miracle for me! i was on wellbutrin for 5 months prior, but it ended up giving me anxiety so i switched. i&#039;ve had depression for over a decade and nothing really took it away -- i did therapy, changed my diet, exercised.. i still felt grey, lifeless and didn&#039;t care much if i died. my depression was never overwhelming sadness, it was quite the opposite: i felt nothing. nothing gave my pleasure. i was just a robot doing what i had to do. it worked quite quickly, about 3 weeks after i started. i will always have depression, but i&#039;m able to cope now. i no longer feel like life is meaningless.. i now do things just for the sake of it. i finally enjoy normal events like everyone else."