"i have been on lexapro once daily in the morning since 2006. i took it in 2004 but had to stop when i got pregnant. i suffer from cyclothymia, which is a bipolar spectrum disorder that includes chronic depression, anxiety, mood swings and irritability. lexapro is a great medicine for those who it works for. little side effects. i currently take 30mg lexapro. i started taking wellbutrin sr 100mg about 5 months ago to help me with my loss of motivation and inability to get out of bed in the morning (i want to sleep a lot). i still have some irritability and mood swings so my doctor gave me seroquel xr 50mg to try 3 hours prior to bedtime beginning tonight."