"i started pristiq 2 years ago and have been on risperidone for about 20 years.  these two drugs have kept me feeling quite fuzzy and warm. there is not much that i can&#039;t tackle in a day. i am like teflon when it comes to negativity. 100 mg a day. no worries. i have lost about 30 lbs and have quit smoking after 20 yrs. pristiq has been my wonder drug. i don&#039;t plan on stopping this medication anytime soon."