"varying levels of depression since early 20&#039;s.  anxiety also an issue.  2 bouts of major depression: one in late 40&#039;s and one in mid 50&#039;s.  no hospitalizations.  now 63 yo.  taking 200mg for 2yrs, -  minimal side effects, and very effective in mood regulation.  never had a manic episode, but had been fairly quick to anger and somewhat argumentative.  i would have to say this medicine has helped a lot.  some changes in my life circumstances may also be helping  (retired) --  but i have to give this medication an endorsement.  worry a bit about taking it long-term -- but so far, no side effects."