"i started the medication on 4/6 weighing in at 242 and i must admit i have seen a tremendous difference after struggling with my weight over the past couple of years. i have been fortunate to not really experience any of the side effects due to me being proactive by taking something for acid reflex after seeing other reviews because i had it beforehand. i must say this is a very exciting weight loss journey; along with exercising and being moderate with my food intake i am down to 229. hint:if you feel full!!!! stop eating this will eliminate the nausea feeling."