"i am 31 and have had acne for my whole adult life. frustrated, i went to the dermatologist and she prescribed doxycycline twice daily with a night time cream (tetrinoin). you must take this medicine with food or else you will feel extremely nauseous. you can&#039;t take it with dairy or within 2 hours of a multi-vitamin. it has been about a month and i have noticed improvement in my skin, although maybe not as much as i would have hoped for."