"this is the only med that actually helps me sleep. i had tried melatonin, zopiclone, lorazepam and temazepam, as well as every natural remedy i could get my hands on and then my doctor suggested quetiapine. i take 25mg about an hour before going to sleep and usually by the time i climb into bed i can hardly keep my eyes open. i&#039;m also taking bupropion (which is technically contraindicated with quetiapine) which may be why i feel so sedated on such a low dose. the only downside is that i don&#039;t fully wake up from it until i&#039;ve been physically awake for at least an hour and it makes me really thirsty. but that&#039;s a small price to pay for getting a good sleep after struggling for years. also it makes orgasms less intense for me which sucks!"