"starting weight 280.  in sept. of 2016 i started taking adapex (phentermine) and took that for 3 months.   i lost about 20 pounds in those 3 months.  i had severe dry mouth, heart palpitations, insomnia and constipation.   when i switched over to contrave i only experienced a slight bit of dry mouth and sleeplessness with a slight elevation of my blood pressure.  i took contrave for 9 months and lost another 50 pounds by eating right and exercising.  after stopping contrave i have regained 12 pounds in 6 months.  mainly due to not exercising and significant increase in appetite.  i will retake the medication and will update my progress as i work toward my goal of 190.  this is a good medication."