"i have been on contrave since nov 24, 2015. the first week the only symptom i noticed was dry mouth. i have not weighed myself yet. although i have already started the medication, i&#039;m not so much focused on the pounds lost than i am with controlling my eating/smoking habits. i start going to the gym next week so i am very excited that this medicine will help me quit smoking and in turn get me motivated to working out and losing the weight. i have noticed i have not been as hungry and i&#039;m drinking more water. i am now up to 2 pills a day and have only noticed a slight headache along with dry mouth, but i will remain positive."