"i started taking antidepressants in january. i started with lexapro and was on it for 5 months. it worked for a while then it just stopped. my doctor raised the mg for it and it still didn&#039;t work. then i switched to effexor. had terrible side effects. i have been on brintellix for a little over a month. due to issues at my doctors office, i had no medication to take for several days. i didn&#039;t notice much of a difference while taking the medication. but once i stopped, i noticed that i was more depressed than before. i was irritated easily and upset. i have noticed i&#039;ve been eating a lot more while on the medication. not okay. and i take it at night because it makes me tired. it has helped my depression some. i&#039;ve felt more like myself"