"i&#039;m only a few weeks into taking this medication and have already experienced great results. i had great skin until i was 21, i started getting severe hormonal acne on my face and back. i currently take spironolactone and epiduo, the combination is working great. i have experienced the medications side effects of having to use the restroom frequently and being dizzy if i get up too fast. to me, the side effects are very livable and easy to adapt to. i think it is important to note the severity of not getting pregnant while on this medication. i was warned that this medication can cause a deformity in male genitalia if you conceive while on this medicine. always check with your doctor first."