"have been on this for 7 months now and have noticed an improvement with my depression symptoms. i started at 150mg and worked my way up to 450mg. i don&#039;t feel as hopeless and sad as i was. side effects were minimal, but my periods have become very irregular since starting the wellbutrin xl even though i&#039;m on yaz. i have been on yaz for 3 years and never had a problem until i started taking the wellbutrin xl, so i am going to discontinue use. if it weren&#039;t for that, i would definitely continue taking it."