"i have been on many medication for depression with associated panic attacks.  nothing has worked but since my doctor prescribed me pristiq cr 50 mg and i can now officially say it&#039;s changed my life! i&#039;m a survivor of many tragic events and feel like i&#039;m not a victim anymore.  i do clench my teeth more often but so what this side effect is nothing to compare to my unwillingness to live!  give it time, three months or more you&#039;ll feel better i promise!"