"started of the 5mg brintellix,  i usually have low blood pressure,   but noticed at first the headache and decided to monitor my blood pressure after taking the med.  usually the headache started about 3 hours after taking it.   i took my blood pressure just to check and my bp was high  142/ 88.   my norm is 108/70, that is regularly.  i don&#039;t think i am going to be able to tolerate the discomfort it gives me with the headache and high bp,  no nausea.   i like the fact the food cravings i got on other meds is not a factor with this.  i was on lexapro low dose for about 7 years,  but it i started to have tremors when i discontinued no tremors,  but depression and sad returned,  so we tried brintellix,  may have to try something else."