"the dr. prescribed this med after i developed a tolerance to prozac after 15 wonderful years.  i started at 25 mg. they always say to give it a few weeks to see if it is working.  after 2 months he increased the dosage to 50 mg. which still did not work.  then after an increase to 100 mg. for a few months, he finally believed it was not working for me.  he started me on effexor, which took another 6 months of gradually increasing dosage to actually kick in.  please do not give up.  after over a year of living a nightmare and feeling suicidal every single day, i&#039;m now back to normal, almost every day."