"i was prescribed pristiq last year for depression &amp; anxiety. at 1st i did not want to take any meds due to a bad experience with prozac when i was 30. i am now in my 50s. after the first day i felt amazingly better. i got up early &amp; felt incredible clarity, focus &amp; worthiness. at that time i weighed 120. i gained 5lbs &amp; probably lost muscle. prior to pristiq i was very physically active. i feel very calm now &amp; go for walks but for whatever reason i do not work out like i did before. soon after getting on pristiq i was diagnosed with hypothyroidism even though i was quite fit &amp; thin. so i was put on levothyroxine for that condition. i would say the weight gain &amp; some sleepiness has been a side effect for me but not sure from which medicine."