"duac is a great acne topical cream but it works better if you take oral acne medications has well. it takes a couple of weeks for skin to completely look better but stick with it. use it once a day before going to bed and i normally cleanse with aveeno clear complexion but prascion as well if you ask your doctor. i have suffered with acne since i was 14 and now i&#039;m twenty and minocycline with duac saved my high school life."