"i have been on lamictal 400mg for 7 years.  i was diagnosed with bipolar 10 years ago this year and prior to lamictal had been on many different drugs with negative results.  i was very discouraged, thinking life could never as it was prior to bipolar entering my life - but then started on lamictal and along with wellbutrin and have not had to change medicines since.  occasionally, i do add topamax to it during the winter months for low moods.  other than that - life is good!"