"i have diabetic neuropathy, fibromyalgia, osteoarthritis with 24-7 all over pain. my lower back pain is very severe and cannot be helped by surgery due to the extent of damage there. i am usually unable to walk due to the pain in my back, hips, knees and leg muscles. i take ultram 100. my doctor prescribed it starting with 1 at night for 3 days, then 2 for 3 days, then up to 3 per day. i do fine with 2 and received an amazing amount of relief and sleep. i am very sensitive to pain medicine, very hard to take. 

i prefer to just take 1 now mostly and also take ibuprofen during the day as well. it helps excessive pain and headache. "