"hello all. i am a chronic pain sufferer, and am allergic to most pain medications. zohydro 40mg er works wonders for me. i take it twice per day, with one 10mg hydrocodone for breakthrough pain relief. my situation is so serious, that at times, i&#039;ve wanted to die. the pain is just that bad, but now i&#039;m getting relief~ it sort if let&#039;s levels it off, and my ability to function without the constant thought of hurting is greater. it&#039;s an absolute pain reliever."