"i just finished my first week of contrave with metformin, and i have lost 11 lbs already. with pcos, this is the first time i&#039;ve seen weight loss like this. i do have some upset tummy and nausea, and i have to force myself to eat, because i am not hungry at all anymore. i am really hopeful. down from 276 to 165. i haven&#039;t added exercise yet, and am really hopeful. will update."