"i have been taking pristiq for 6 months. the first two months, nothing happened. the third and fourth months were great. i was well balanced, no longer angry all of the time. i had motivation to do things, and i felt like i finally had the ambition to do something with my life. and then pristiq just stopped working for me. as if my body had grown immune to it. i am still talking it regularly every day but i feel just as horrible as i felt before i started taking it. i am going to see a doctor next week to find out why it just stopped working for me. it&#039;s not fair! i read so many reviews on how it has changed peoples lives and fixed their depression. i was so happy to think that i&#039;d gotten the same result. i can&#039;t find a reliable drug."