"i was switched to opana from oxycontin because even 150 mg of oxy a day wasn&#039;t managing my pain anymore. opana was said to work just as effectively at lower doses, with fewer of the miserable side effects of oxy (constipation, drowsiness, etc.). i have found that to be the case in general; my daily dosage is more like 50-80 mg per day on this med and i can go to the bathroom again without using a suppository first. my pain control started out slightly better on this med, but since i&#039;m a fast metabolizer of opiates, i&#039;ve started developing a tolerance to this one, too, and the pain is bothering me again to the point where i can&#039;t function. my major complaints about this med is that it is very hard to find, and it is costly."