"i have been on trazodone for 3 years now in 300mg tabs from the very start. it makes me nauseated but am unable to do to a hernia repair that was done.  also suffer from dry mouth.  the medication has worked great from some time.  i find it better to take it without food because it starts working within a hour.  if you take it with a meal or a light snack it takes about 2 hours to start working. so depending on when you take it may cause some the that groggy feeling in the morning.  recently i have notice it doesn&#039;t have the same effect on me. now i have nights i can&#039;t sleep.  "