"i have been treated with cns stimulants (methylphenidates and amphetamines) and adderall has unequivocally been the most beneficial medication for adhd. i have been on this medicine, 30 mg twice daily, for about 4 years and all of the major symptoms of adhd are under control which in turn has allowed me to take back control of my life.  

i would like to add that, for me, it has had a profound positive effect on comorbid major depressive disorder, recurrent (moderate-severe). tried virtually every antidepressant and various combinations/augmentations since age 22 (except for maois) with little improvement. now taking pristiq 50 mg in the morning and a low-dose of mirtazapine (generic for remeron) at bedtime. no relapse/recurrence in over a year!"