"i have just started on serzone (nefazodone) after reading up on it. i have tried so many other ssri&#039;s that did not work so i am hoping that this class of drug will. i wish people wouldn&#039;t worry about the the liver issue. depakote and cymbalta both have the same risk but they haven&#039;t been pulled off the market due to the bad rap. i decided to try serzone regardless of the liver issue. i will have my liver checked at least every 6 months and if it becomes abnormal, i will stop taking serzone. no big deal. it is as simple as that. but i read that the risk is only about 1 in 250,000. i will take those odds if this drug really helps me. so far i feel drowsy but i can live with that. the alternative is debilitating fatigue and horrible negativity."