"there are a lot of negative reviews about this medicine and it&#039;s side effects, and that makes a lot of people beginning the medicine, including myself, freak out. the people having a positive experience with lexapro are out living life. don&#039;t be discouraged. for me, lexapro started working in the second week, but would work on and off for the first month. i started at 5mg and slowly went up to 15. i&#039;m on week 5 and it hasn&#039;t done much for my anxiety (yet) but it has helped my moods tremendously. for the first month i had muscle aches and headaches, and i was really tired and unmotivated. that went away in week 4 and i&#039;m feeling better than i have felt in two years."