"i have been taking qsymia for almost a month now and have lost 11lbs in 22 days. i am on a low calorie diet. i have had several side effects like constipation, insomnia, numbness in face and legs. any carbonated drink taste like its been sitting out open for a day just flat no fizz at all. i do feel irritable at times but most side effects i can manage except the constipation that just plain hurts. i have an appointment on march 28th and i&#039;ll see how it goes with my progress and labs. i was at 290 lbs starting weight and i am down to 279 lbs. seeing my belly shrink motivates me more to exercise and continue to eat healthier. it is quite expensive but i look at it like this, i waste money on other things that don&#039;t do me any better and this will."