"this medicine has helped about 95% with my depression and about 75% with my moods i have been on it for about 3 months now i go through periods where i am so happy and so in love with my husband very high libido (feelings i have always struggled to have) but there has been about 2 weeks during this 3 months that i go back to being irritable and moody and wanna smack my husband for everything that comes out of his mouth. so being on these medicine and being bipolar maybe i&#039;ll never be 100% normal."