"i started suffering from moderate cystic acne in my mid-30s and aczone is the only medication that has helped (aside from oral antibiotics, which i didn&#039;t want to take long term).  i noticed a difference almost immediately.  i&#039;m now 3 weeks into my treatment plan and my skin is perfectly clear.  i use aczone in the morning, glycolix 5-2 pads late in the afternoon, and tretinoin 0.05% at night.  i moisturize dry spots with skinceuticals phyto corrective serum. my skin hasn&#039;t looked this good in years!"