"started this med on june 2nd 2015  with 75mg no difference a month later, i am up to 150mg no difference scrappy mood no desire to do anything.  i drag my self out of bed every morning i am now on 300mg a month later hopefully some miracle would happen i am going to give another month with the 300mg dose, if there is no change, i am trying some thing else. i am so sick of this drugs that take weeks to work and then no result so you have to try something else.  i&#039;ll  keep you posted.  by the he way today july 26  is my 3rd day on 300mg. wish me luck"