"i was started on pristiq 50mg a year ago when my moods started to get out of control, as well as my anger. i was so angry all the time, and i felt like i was always on the verge of crying. i experienced no side effects whatsoever from the pristiq, and felt a noticable difference within a week. i&#039;m not angry for no reason any more, and i don&#039;t feel like i have to cry when i drop a spoon. this medication worked wonders for my depression, anxiety, anger and invasive thoughts. my doctor increased the dose to 100mg after i plummeted emotionally, despite the pristiq. the increased dosage worked! i&#039;ve been on 100mg for 6 months with no side effects and no complaints."