"my dermatologist put me on this and i had to pay $180 for one tube! a little does go a long way though. at first when i tried this my skin didn&#039;t show any signs my dermatologist told me to wait six months! i couldn&#039;t bear it so i stopped using it and tried clinique 3 step. it helped after 3 weeks but then i never saw any major changes so i used ziana with clinique and it worked great. my face isn&#039;t acne free yet but it&#039;s getting close after a while though the toner and moisturizer made my lower face flake unbelievably, so i stopped using it and now i just use the soap 2 times a day and ziana at night. it has worked wonders. good luck."