"my experience with this drug is a bitter sweet one. however, the bitter side to it overpowers the sweet by long shot. since i was a kid, i&#039;ve had behavioral issues and it wasn&#039;t until i was in my mid teens that they began to truly effect my way of life and my relationships with those around me. i had been taking bupropion in combination with sertraline and had no serious problem or complaints. however, when i started to wean off of the sertral and began taking the strattera, i began to get irritated and just downright pissed off for no apparent reason. the slightest things set me off, and it&#039;s only gotten worse with increased dosage. i&#039;m gonna stop taking it all together. screw a bunch of this unprovoked anger stuff. it helps no one."