"i take 300mg of serequol xr at night time with antidepressants it puts me to sleep as i wouldn&#039;t be able to however i&#039;m knocked out until the morning if i don&#039;t take it everyday i get major withdrawals symptoms even if it&#039;s on 48 hrs so will be interesting in seeing how i get off it over the next couple of years but has improved sleep and mood"