"after my first major breakdown in which i was diagnosedd, i spent a year trying different medicines. i felt like a new (or like my old) self within a couple days, on this miracle drug. my dosages have varied depending on the other medicines (antidepressants and add medicines) i&#039;m on. the only major side effect i&#039;ve had that never went away (been on it for 7 years) was the sedation in the morn ing (i took my whole dose in evening). now i take 20mgs 3x/day and 40mgs at bedtime, then 20mgs when required for anxiety. right now i also take wellbutrin xl and i&#039;m titrating up on abilify due to breakthrough depression. geodon helps both mania and depression and i found it to be very weight neutral."