"seroquel really snapped me out of a terrible manic episode. the self-injury, obsessive thoughts and sleeplessness stopped within two days of my first doses. currently it is a regular part of my drug cocktail, at a maintenance dose of 50 mgs. it is the only drug that has truly been able to hold the mania at bay. i have had weight gain, but i will select weight gain over a living hell every single time. seroquel makes me happy to be alive again."