"i have ankylosing spondylitis and have been on 3 or 4 pain relievers since 2008. i am now on 10mg ir x 3 daily and 30mg er x 3 daily. i am getting very little relief; however, i have read many reviews where people taking opana praise the medication. on the pain scale level, i am generally at 7-8 w/o the medicine and 5 or 6 with the opana. i guess i need to talk to my provider and see if there are some different options..."