"day 3 of monodox: my acne is starting to clear up. i&#039;m on 75mg 1x a day. sinus stuffiness/drainage, diahrrhea, muscle weakness, and a headache when i run too hard. i&#039;ve read really good things about this medicine, that&#039;s why i opted to fill my prescription. super expensive without insurance and a discount card my dr gave me. hope the side effects subside."