"hi all, i left my opinion last year around october. and things have changed just a bit. i understood my illness is genetic bc my uncle had it and my dad has it but don&#039;t accept it i guess. anyway 70% of cases have a genetic background so feel better about that. you didn&#039;t chose this. i feel lamictal is not working as well after two years but not a major change. i will increase it from 200mg to 250 this week. i control my depression with clonazepan. i feel anxiety makes depression worse. so when it kicks in then i feel stronger enough to make a prayer and it goes away.we need to do some work in our brain. everything that is negative you change it for &quot;yes&quot; and i can and i will."