"i have several issues and was given remeron along with seroquel and tegretol, i take it at night and i sleep now, its pretty amazing but i&#039;m so tired after taking it that i can&#039;t keep my eyes open no matter what. in the 3 weeks i have been on it i have gained 3lbs which is awesome for me. i hope the sleepiness dies down some as it is a bit strong for me, but overall this is a great medicine."