"almost 6 weeks on contrave and still going strong. i&#039;m down 13 lbs; 168 at 5&#039;1 to 155. side effects i&#039;ve noticed this far, still bouts of nausea and only threw up once. i recommend taking with food and lots of water. dry mouth seems to have subsided, still have a slight hum in my ears and my right hand twitches mildly intermittently. i have energy, an overall feeling of well being and 90% control over my eating. sticking to a 1400 calorie or less diet with no trouble. scale down program is very encouraging. i feel like i eat breakfast, small lunch and then am just not hungry the rest of the day, amazing how it turns off desire to eat mindlessly. some taste changes, i love eggs, but can&#039;t eat now. pls try for yourself, or you&#039;ll never know."