"i have l5-s1 problems and s1 renervation/denervation causing mild foot drop plus i just had slap tear (shoulder) surgery in february of this year.  i&#039;ve used tramadol for so many years that i&#039;m pretty much immune to it and i can&#039;t sleep if taken past 4pm.  nucynta acts totally opposite for me. i take it with 75mg of lyrica and 0.25mg of alprazolam before bed and i&#039;m sleeping better than ever. nucynta might make you nod.  i&#039;m a hyper person and it puts me down. enjoy!"