"after a horrible two years on prozac pristiq came in like a saviour. it reminded me what my normal thought process was without depression. i started on 50mg and 3 months in upped it to 100 and most of the time it&#039;s great however like everything tis not perfect. i have good days and bad days. i often have a few weeks of good days and when it&#039;s bad it&#039;s really bad; no motivation, suicidal, depressed, anxious. i also notice that if i miss a day or two i go through major withdrawal and that leads to similar symptoms as a bad day. overall it really did change my life but it&#039;s not perfect."