"love it! this medication can have a tough adjustment period. but i took 1tsp of benadryl with it at night and that helped me adjust. as long as you don&#039;t have symptoms of allergic reaction then my advice is hang in there. saphris is by far the best medicine! i now take 5mg in the morning and 5mg at night with zero side effects. this med has made all my anxiety and paranoia associated with mania dissappear! i have been using free samples so far but the cost will be worth my health and sanity!"