"i&#039;ve been on vyvanse for a year. i take 50mg now and i wouldn&#039;t say it&#039;s a miracle drug, but over the past year i have attended more classes and gotten more consistent grades in university. i definitely have to put in the effort to experience the benefits; it&#039;s not motivation/focus-in-a-pill for me! the side effects i&#039;ve experienced are increased anxiety, dry mouth, increased perfectionism, irritability, and some insomnia. its impact on my mood varies. at first, my appetite decreased and i had terrible afternoon crashes, but they have levelled out over time. overall, the pros outweigh the cons for me. i haven&#039;t tried anything except for wellbutrin, which i still take. not sure how they interact."