"it&#039;s always a test of one person. everyone will have anti-depressants that work best for them. i tried lexapro and wellbutrin. i hated wellbutrin. prozac gave me zero side effects. no sexual frustration, no irritability, and no insomnia. i&#039;m on my 6th month and just got bumped from 20mg to 40mg because of seasonal depression and feel a huge deal better. i&#039;ve lost 10lbs in 3 weeks because my appetite and drinking are also under control. i&#039;ve also heard prozac is associated with weight loss. if something isn&#039;t working for you, give it a try. "