"i had to taper off my lexapro while starting this. i did a wk of the 10 mg during that and now i&#039;m on my 2nd wk of 20mg. i&#039;m not having any side effects like others have mentioned, but i&#039;m not seeing any benefit yet either. i just spent 3 hrs yesterday crying, and then alternated that with being angry about everything (torn window screen, broken handle, garage motor quitting-everything was crap!), then i&#039;d sob again. i hope this picks up soon, as does my family! however, i&#039;m also 46 and wonder if some of this is pre-menopause??? maybe i need to call my dr. and have the dosage increased now? otherwise, i see him again in 5 wks. i just don&#039;t know, but my dr has high hopes and praise for this medicine."