"i&#039;ve been taking  quetiapine for over 15 years, i started off taking 25 mg and over the years it was increased to 1000mg a night. recently found out that my liver is double the size and i am quite concerned. i have been lowering my dose to 450 mg a night with clonazepam and i am still sleeping. i haven&#039;t had vivid dreams but started getting panic attacks last year. to be honest i am scared of the affects of taking this medication for over 15 years, my doctors, while being concerned haven&#039;t checked my blood regularly and now i am scared to death about my liver, reviews say that i need to stop taking this drug..but it works... please make sure that you are having regular bloodwork done every 3 months. but this is the best sleep aid out there!"