"i couldn&#039;t really tell whether it worked or not for bipolar 1 disorder.  i was on a few different medications at once:  lamictal, lorazepam (as needed), and for a brief time, seroquel with the abilify.  the dose was 5 mg since i was experiencing a mixed episode with some paranoid thoughts.  i didn&#039;t notice it being particularly helpful for depression.  maybe there was some slight mood stabilization, but not enough for me to really feel relief.  i was taken off of it for this reason.  also, even at 5 mg, it caused me some restlessness and a sensation similar to a headache.  it&#039;s expensive too."