"i have been on cymbalta for almost 4 years now and it has been a lifesaver for me.  the first few weeks i had some loose stools, but that subsided.  the only problem i have with it now is keeping weight off.  i have trouble loosing weight and i think it is due to the cymbalta.  i eat a well balanced diet and exercise.  however, due to the numerous medicines i had tried before that failed me for anxiety and depression, i will keep taking the cymbalta.  i&#039;d rather be fat then feel the way i felt before."