"i was diagnosed with depression about 6 months ago and started with a very low dose of prozac. about 3 months later i was institutionalized and switched to zoloft. most of the people there for depression were on it and it worked for them. however, it does not work for me at all. i&#039;ve been on 100 mg for about 2 months and i feel jittery when i sit for too long or when i&#039;m trying to sleep, i get really grouchy and rude (which is unusual for me) , and things that only bothered me before make me really depressed."