"every persons body is different, but i have had a horrible experience with this medicine. i switched from lo-estrin 24 fe to tri-sprintec because of the dramatic price difference, but immediately switched back after three days of feeling like i was dying. horrible headaches, extreme nausea, black outs, and i was even randomly losing my vision. like i said everyone is different, so you won&#039;t know until you try, but if your body is accustomed to lower doses of hormones and you switch to something higher, it isn&#039;t a good result."