"i am having such a hard time with anti depressants (low tolerance).  i have been on trintellix for 6 weeks-started on 5 mg currently on 10 mg.  from day one i have had severe side effects: constant nausea, headaches, diarrhea, extreme fatigue, weakness, and restlessness to name just a few.  my mood has been so bad, wanting to crawl out of my skin, crying and very agitated and hostile.  

my constant nausea has finally stopped but now i can&#039;t eat anything as i feel sick.  i am stopping taking trintellix as i am concerned about how angry i have become since being on this drug.  i am angry at anything and everything.  have never had this kind of reaction to any of the other ads and am worried about how intense the anger is."