"age 48 and have struggled with depression for years. i have no other mh disorder and had no luck with antidepressants. prozac increased suicidal ideation and with zoloft i felt occasional &quot;zapping&quot; in my brain (i have no other way to describe it, but it&#039;s happened to others). finally decided to try wellbutrin 150 mg qd. i&#039;m mad at myself for not trying it sooner! now, depressive episodes are very infrequent and last less than 30 minutes. the low is very manageable, however at times when i should be sad, it&#039;s like i can&#039;t be. i also have tons of energy, when in the past i&#039;d struggle to get out of bed. unfortunately i haven&#039;t had any weight loss. the down side is that i am experiencing some insomnia, but i&#039;d rather that than the alternative."