"just started hysingla er 30mg but with norco 10\325. the pain dr and i have been trying several ir and er pain relief medicines.  i have chronic pain after back surgery l5-l3, plus fibro and arthritis. so i hurt from head to toe literally. i won&#039;t give up norco until i know new meds work. that&#039;s our agreement.  i have had only 3 days on hysingla. i tried mornings but it kept me up that nite so switched to 9pm i think it peaks about 10-12hrs in. i sleep ok. i need to be able move normal again during day! i really can&#039;t tell i&#039;m taking it as i&#039;m still taking norco every 4 hrs. they&#039;re not great either but least it works somewhat on back pain. i noticed on the 2nd day i&#039;m starting to itch.  if it doesn&#039;t let up i&#039;ll have call dr office for something else. i hope not i&#039;d like to give full month trial. may be it is too low dose for me."