"i&#039;m a middle aged woman.  along with my first hot flash about 10 years ago, came the weight gain.  since 2008 i had gained about 50 lbs.  then, in the summer of 2016, i was in a clinical trial for dasotraline. by the time phase 1 had ended, i had gained 30 lbs, now weighed 225.  i&#039;ve tried every combo of diet and exercise through the years,  i threw in the towel and was basically waiting to die. about 3 weeks ago, my head popped out of my butt and i decided i deserved to be happy and healthy.  back in the gym, clean eating, and no diet soda.  the scale did not move. i had my physical.  doc prescribed qsymia.  insurance did not cover.  my 1st weeks was reduced to $60 not free!!  i&#039;ve been on for 3 days.  no changes yet  i&#039;l keep you posted"