"my doctor noticed that the other medication that i was on was not working well and had me start brintellix (10 mg per day) from samples he had. there was a direct transition from the other medicine to this one - no tapering off or anything like that. after just a few days, the medicine and i apparently agreed that it would work for me. the side effects that i have are mild headache and sometimes loose stool - to be polite. i&#039;m excited about this one. big differences in a short time."