"i respond great to contrave.  i&#039;ve been on it 3 weeks and i&#039;ve lost 10 pounds.  i have reduced the number of calories i eat down to 2000 but sometimes i eat less and sometimes i eat more.  i am 5&#039;9 382 pounds.  i have stopped drinking soda as well so i&#039;m sure that helps.  i was on this medication before and lost 50 pounds but had to quit due to the cost and gained all the weight back.  hopefully this time i will lose the weight and keep it off."