"hello i am on week 4 of contrave and i have lost 22 lbs. i did experience some negative side effects mostly headaches and fogginess. i feel much better now the side effect have seemed to subside. my dr put me on a 1000 calorie diet and it has been rough but the contrave helps by no means does it eliminate your appetite completely. i don&#039;t think i would have been able to stick to such a ridged diet if not for the medication. also i walk 45min daily and do occasionally go over my calorie limit but just by a few hundred. all in all i would recommend this medication as long as you stick to a calorie reducing diet and some exercise. the pill doesn&#039;t make you lose weight it just really helps you stick to a healthy eating plan."