"ive been on zoloft (75 mg) for about a month now, and im just starting to feel the effect. ive depression and anxiety, and all i can tell is that im still very sad but it&#039;s not the end of the world as before. i still cry sometimes but i dont want to kill myself anymore. but its strange not to feel like i used to be, i have the sensation that im functional and under control, but at the same time i feel like a robot or zombie, and thats weird, im not totally myself. but i guess this is better than the horrible anxiety i used to have. sometimes i have headaches, im very sleepy and sweaty and talkative. anyway, it is helping me for my anxiety, but depression barely improved."