"i was prescribed tramadol for depression a year ago (50 mg, 3x day).  i felt like i had the flu so i stopped after 3 days. about 1 1/2 months ago i started to take it again (only 1- 50 mg per day in am).  i currently take adderrall and xanax as they are the only meds that help my depression /anxiety without the terrible side effects. since on tramadol i have been more motivated and productive then i can ever remember!  i stopped for a couple days and experienced the flu like symptoms again, but i have gone back again on a regular daily schedule.  not sure if i should up the dosage to 100 mg but this has been the best med for me, and i&#039;ve taken many. definetly a life changer and i&#039;m optimist about the future for the 1st time in my life."