"i haven&#039;t been on topiramate very long, only a couple of months.  started taking it for rls (restless leg syndrome).  i was really surprised to see that it is sometimes used as a weight loss medicine. i didn&#039;t really notice any difference in my appetite.  however, my last visit to doctor did show that i&#039;ve lost 5lbs.  i don&#039;t like the tingling, crawling skin sensation side effect.  that went away after a few days."