"switched from butrans 20mcg to nucynta er 100, but wasn&#039;t enough for mid to end of work day, so pm switched me to 200mg x 2 daily. so far so good, no side effects and much better control of the pain along with being in a better mood overall. degenerative disc disease and muscle spasms are my main culprits over past 8 years, 33 now. i&#039;ve gotten to the point where epidurals seem to be the only thing that will allow me to live a close to normal life. 

nucynta has really kept things at a manageable uncomfortable level compared to before. i hated the roller coaster of non er (extended release) meds and highly recommend making the switch if permitted."