"i started taking spironolactone over a year and a half ago for moderate-severe acne that had been giving me awful self esteem, i was afraid to go out, and i was so depressed i was not myself anymore. spironolactone has given me back my life. i didn&#039;t think it would ever be possible for me to feel pretty without makeup, but i&#039;m starting to. i did have a terrible breakout about a month after starting spironolactone that almost pushed me over the edge; it was miserable. but it cleared, and has continued to do so. it took at least 3  months to see the results i hoped for, but it has just gotten better and better. i&#039;m just hoping this is a good solution for me long-term; i want kids someday and i know i will have to stop this med before pregnancy."