"i have been taking 15mg at night before bed for 7 months now for anxiety, depression, weight loss due to a c.diff. infection (antibiotics). mirtazapine, along with 20mg of fluoxetine has literally saved my life. i had been on only ssris before, but after this last bout, nothing was working. i had lost 25lbs and could not sleep at night, was crying all day, not eating, pacing all night, and wanted to crawl in a hole. i have gained the 25lbs back (and then some), have a ravenous appetite all day long, but it subsides when i exercise regularly. i sleep through the night and wake up refreshed. my partner is happy, too (no sexual side effects). love this medicine."