"i am a 52 yr old female weighing 160 pounds.  i started the low dose 14 day trial about 2 months ago.  i lost 2 lbs. immediately.  side effects were, loss of appetite &amp; constipation.  when i started the higher, 7.5 dose, my digestive system instantly shut down.  i took a stool softener &amp; laxative daily &amp; i still could not go to the restroom.  i drink 70-85 oz. of water &amp; take &quot;it works&quot; &quot;greens supplement&quot; daily to get a decent intake of fruits &amp; vegetables.  long story short, i can only take 1 pill once every 5 to 6 days; otherwise i am miserable and extremely stopped up.  since getting the prescription filled on may 14, 2016, i have only taken 7 pills.  i have an appt to see my doc in a few days.  have lost 3 pounds."