"i think this stuff works great as long as ur not a habitual user of the stronger pain killers. i&#039;m allergic to nsaids and aspirin so i can pretty much only take tylenol and the occasional cox 2 inhibitor (celebrex, vioxx, bextra). i took tylenol and celebrex yesterday for leg pains and got no relief. used tylenol today. no relief. i took a 50mg tramadol and pain gone!!! i have a high tolerance for certain meds but for pain, i&#039;m an over the counter kinda gal. this is great for single doses! maybe not for daily regime :-/."