"i never had add or problems focusing and staying motivated before i had chemotherapy for ewing&#039;s sarcoma at 16-17 years old. i&#039;m now 24 and started being treated for those symptoms with focalin xr earlier this year. it was night and day difference for me. i had energy, yes the first week i was shakey but that stops, i lost weight gained from conituning to eat like a weight lifting football player but had very little movement at all. i felt great, i can get things done now. motivation is now just lacking from my lack of trying but when i get on something i blaze through it. negative effects i have experienced are occasional moodiness, especially if i am focused on something and then get interrupted. caffeine is a no no."