"absolutely amazing. i have been treated for bipolar/major depression since i was an adolescent. been on everything under the sun. some did help-but nothing kept me consistently on an even keel. by the time my dr gave me samples of latuda-i had no expectations. for the first time in my adult life i feel normal. my mood is relaxed and happy-i&#039;m sleeping well and no excessive hunger. it does kill your libido-but that is fine with me-i have lost 7 lbs. i started on 40mg and gradually increased to 120mg--i also take 300mg wellbutrin, 30mg adderell twice a day and ativan as needed for anxiety. this medication is life changing."