"female age 40 height 5&#039;2 305lbs. started contrave on 3/29/17. week 1 i lost 6lbs!! now 299lbs. i am pre diabetic and my doctor put me on metformin. this was a big wake up call for me. i feel mentally ready to do this. so far symptoms have been nothing bad a few stomach cramps, food taste blah, a little nausea but only when i don&#039;t drink enough water. i do go to the bathroom more often about 4 times a day. i don&#039;t have cravings and i feel full. i have changed my diet big time, no carbs, fish and lean meats, lots of eggs, tons of water and small snacks throughout the day. i feel good, no tiredness like others that i read. i will continue to update weekly, i feel this will make me accountable and it may help someone who is like me struggling."