"i have pcos and i had gone without a period for 10 months. my doctor put me on loestrin. i was extremely moody and emotional, crying over everything and very depressed, plus i was spotting and bleeding almost constantly. ortho tri cyclen lo is the second pill my doctor prescribed, and i am beyond happy with it. i don&#039;t even notice that i&#039;m taking it. there are no mood changes, i have lost a little bit of weight and it has even helped with my rosacea. my periods are coming around the same time every month, which is wonderful because i am finally able to know when to expect it, something that i have never been able to do. the only complaint i have is bad cramps, but they only happen in the first couple of days."