"i hope this helps to all the depressed people out there. i have been seeing a psychiatrist for drug induced depression.  i abused meth, vicodin, coke, and any other drug you can think of for years and that has left me a basket case. i have tried many antidepressants but i suffer too many adverse reactions for the stronger stuff. i am currently on 300mg wellbutrin and 15 mg deplin and i have to say i feel great! however i had taken wellbutrin/deplin combo in the past and it stopped working for me after 6 months.  the results with the antidepressants were a little funny because i went back to abusing vicodin. now i am clean of any drugs and just taking what is prescribed by my doctor.  300mg wellbutrin and 15 mg deplin. "