"before being diagnosed with bipolar disorder, i was on this antidepressant, along with zoloft.  it gave me manic symptoms, so beware for those who may have undiagnosed bipolar.  plus, on 300 mg, i felt terrible, as if i was sped up.  physically, it made my heart race and caused agitation.   lowering the dose to 150 mg was better physically (before being diagnosed by bipolar, but then i was taken off of it completely).  whether on 150mg or 300 mg, i noticed insomnia.  i have also heard other people say this who aren&#039;t bipolar, although i&#039;m sure for some, this works wonders."