"i have been on pristiq 50 mg for 2 days now.  i suffer from a host of illnesses, fibromyalgia, cfs, migraines, depression, etc. i have noticed a tremendous increase in my energy in just 2 days. however, i have been having severe abdominal cramps after eating (and i am eating light), but my psychiatrist advised me that the stomach pains should subside shortly.  i finally got through a day with a much more positive attitude."