"i had been taking ortho tri cyclen lo but had to switch to this generic tri lo sprintec. i started it on vacation with my fianc&eacute; in hawaii and it made me so moody, irritable, angry, and crazy! not much can ruin a vaca in hawaii, but it definitely caused me to start a lot of fights with my s/o. seriously, these side effects are so real. i&#039;m sure it affects everyone differently, but i&#039;m switching right away. that&#039;s the first thing my fianc&eacute; said to me too- caused me to not act my normal self, cry about everything and make everything a difficult situation. such a terrible experience. no babies though.."