"38 year old femaie, working mom and wife, 3 year old son, years of depression and anxiety augmented by c-section/spinal surgeries beginning 2006. 

lexapro - prozac - wellbutrin -- all failed. pristiq broke through the darkness ... but after a very rough period of uptake. took three weeks -- almost to the day -- to achieve a positive impact. continued wellbutrin with pristiq 50 mg 1xday morning dose. also suboxone for opioid dependence management 8 mg daily.

i used to have suicidal thoughts, anxiety, sweating, fatigue, inability to focus or concentrate ... then one morning things were different, i felt better, i felt like me again! pristiq works, but buckle your seat belt while it gets into your system."