"well i just started the medication two days ago so i can&#039;t really say yet. but i can say the first day of taking it, i had the worst headache . but today, i haven&#039;t had a headache (knock on wood) i just hope this works, it&#039;s a struggle to shed pounds. i really just need a jump start. i&#039;m curious what time do you guys take the second pill? is it 12 hours apart? i will report again soon"