"i have been the guinea pig, like most of us who suffer from anxiey, depression, ocd tendencies, etc.  i have tried more &quot;psych&quot; meds then i care to count.  some did nothing.  some made me physically sick.  one made me homicidal.  i have never been a fan of narcotics.  they too do not agree with me.  after herniated disc/back surgery 3 years ago, dr said i needed to take at least something.  so i got tramadol.  200mg a day. if i had pain, i was too calm and happy to notice.  life was great!  i had energy and focus.  i was on this regimen for about 20 days.  about the third day into not taking tramadol, i felt like hell!  talked with pcp who pulled me off lexapro and now i take this.  do have .5mg xanax for bad panic attacks.  i feel amazing!"