"have been taking sertraline for 3 months and it has changed my life. was prescribed it for anxiety which had led to depression. was hesitant to take it (bad experience with cipralex 7 yrs ago - no emotion/ loss of inhibitions) but my doc said this had less side effects and prescribed 50mg. 1st week was horrible, nausea, spaced out, twitching etc, libido was 0 and had anorgasmia (like you&#039;re not depressed enough!) noticed an improvement in energy after a week, things felt lighter and i was able to think more clearly and from then it&#039;s just been a steady improvement. 3 months in the depression is gone and my anxiety is at a normal level. i still feel emotion and best part is the big o came back after about 8 weeks!"