"been on mirtazipine for two years now. 45 mg at first must admit was not very enthusiastic as i had tried a few others but must admit given the way i was at the time was a godsend to me !! it took a good while to get into my system at the start . sweats . nightmares and even more panicking but once they started to work i have completely changed my life !! i am now back performing on stage singing and nobody would ever know that i suffer with depression! but one thing i am aware of is  if i run out of my pills .. like i did when i went on holiday and decided to stay an extra 10 days !! i was in the world of trouble !! .. the withdrawal from such a dose is absolutely terrifying!! and needs to be done with support and doctors!!"