"this med did its job reasonably. didn&#039;t necessarily keep me out of the dumps all of the time,  but i could cope with life better. started with 37.5mg er, then switched to sertraline for 2 weeks due to insomnia. went back on ven but now 75mg immediate release for 1 month, then 75mg er for another, then 150 mg er after feeling like 75 wasnt enough. was only on 150 for 2 weeks after realizing i gained 15 lbs!! wtf?? i didn&#039;t eat a lot because it did suppress my app. but i was constipated all of the time. just wanted to lay in bed most of time. moved on to bupropion, but thanks venlafaxine for being there i guess? you&#039;re like the brother who kept me company but never cleaned up after yourself."