"i have been diagnosed with mdd, gad, and ocd. i have tried many medications including lexapro, wellbutrin, and effexor. after a major depressive episode during the summer of 2009, i was prescribed pristiq at 50 mg. within days i was feeling energetic and happy with no side effects except weight loss! in addition, i am slowing weaning myself off of cymbalta. cymbalta worked well for my anxiety/panic attacks for the past four years, but left me with no sexual desire. i am down to 30mg from 60mg. i take klonopin 2x daily as well. pristiq was truly a life saver. i just hope once i&#039;m off cymbalta i can reach the big o."