"i had severe depression on and off past few years. this time round it was unbearable and i was literally falling apart mentally. sadness and torment, that would not go away, anxiety and lack of sleep for over a year etc. i refused taking synthethic meds and decided to give niacin a go.
it worked pretty much instantly. i started on about 300mg (severe flush like sunburn and itchy skin), then calmness. i was upping the dosage almost each time, and flushes eased eventually.
 now (2 weeks later) i take 1500mg 2-3 times a day and the flush is slight with warm face and chest. 
sadness is gone and i feel much more &quot;with it&quot;. it seems to be blocking unwanted thoughts. hands down- a true depression cure."