"i will give this a 2, simply because of the ease of use.  the tabs dissolve under your tongue so you can take them anywhere.  you cannot eat or drink for 10-15 min afterwards, which is really not a big deal.

i am bipolar i with occasional mixed episodes and was prescribed this medicine (5 mg 2x daily) in the middle of a mixed episode while in the hospital.  it propelled me into full-blown mania.

as with all medicines and this disease, its very personal.  this medicine might be more appropriate for someone less prone to mania than myself.  i am on topamax 150 mg (50 mg 3x daily) and seroquel 100 mg nightly, now.  i am not cured by a long shot, but i am certainly a lot better now, a month later, than i was on the saphris."