"i&#039;ve tried a few antidepressants over the years (citalopram, fluoxetine, amitriptyline), but none of those helped with my depression, insomnia &amp; anxiety. my doctor suggested and changed me onto 45mg mirtazapine and this medicine has saved my life. thankfully i have had no side effects especially the most common - weight gain, i&#039;ve actually lost alot of weight. i still have suicidal thoughts but mirtazapine has saved me."