"as like so many others have posted, i too have had major depression,bi-polar disorder,and anxiety. i&#039;ve been on every med imaginable for these diagnoses and they all have stopped working. my current regimen is cymbalta 90mg bid and zyprexa 5mg @bedtime. i now have been taking gabapentin 400mg tid. (i&#039;m also a recovering opiate addict.) anyways, the gabapentin seems to give me a pleasant type of calmness. i am saying tons of prayers that this is the missing piece for me. i&#039;ll try anything to get my life back. anything"