"i&#039;m 27 &amp; struggle with hormonal cystic acne. i have been on this medication for about 3 months now. prior to bactrim, i was taking minocycline. minocycline worked great but i developed a resistance to it in july 2013. from july 2013 i tried doxycycline, then erythromycin. i struggled trying to find a solution with my kaiser dermatologist until i went to another dermatologist in june 2014. june 2014, i tried bactrim &amp; it started clearing up my skin 3 days after using it. i was prescribed to take 1 pill twice daily. i take 1 in the morning &amp; 1 at night. this medicine has saved me from depression, feeling dirty &amp; ugly. i hope i don&#039;t develop a resistance to it. my skin is completely clear."