"effexor might have saved my life because at the time i was given it i had damn near given up hope.  paxil and zoloft did nothing. depakote attacked my liver. lexapro made me numb. then effexor was given to me. 2 weeks after taking it i felt better. 4 weeks later, i was back doing things again. within a year i had all my interests and hobbies back. 

cons:

1.  withdrawal is terrible. when i miss a dose i feel it. neck pain. headache. 
2. i&#039;ve found that i had to increase the dose after two years of usage 75 mg 3x times a day holds me.
3. not really a con, but when more stress then usual i relapse for a few days with depression but it goes back to normal if you increase dose for awhile."