"i have been taking 20mg of parnate every day for a little over a month now after finally convincing my psychiatrist to prescribe it. i really can&#039;t say how effective it has been in terms of alleviating the symptoms of my depression. diet restrictions have not really bothered me at all . no real physical side effects apart from extreme sun sensitivity. this really bothers me because i&#039;m extremely fair skinned and burn so easily - frequent, and i mean frequent reapplications of sunscreen and sun avoidance are a must for me. parnate has also decreased the effectiveness of benzodiazepines such as valium and imovane. this has been really frustrating because i also suffer from anxiety and insomnia."