"i was given topiramate for migraines and had 8 days left of phentermine. so i used them together. i can&#039;t say for sure which was more responsible but in that month i lost 25lbs. i did finish the month on topiramate without the phentermine and part of this month june. i picked my new script of phentermine and started taking it on the 27th. so it is day 3 of the combination and i have lost 28 pounds. so something is working and i have much fewer migraines as well. insurance covers topiramate not phentermine."