"i have been treated with lexapro, zoloft, pristiq, klonopin and lamictal and none were effective. i have been taking cymbalta for about one week now, and still don&#039;t feel any different. i wake up every day feeling 100% anxious and find it extremely hard to get out of bed. it has been this severe for about two months now where i feel totally incapable of living. doctor said to stay on cymbalta and see if it changes anything. feeling hopeful!"