"this drug has been a miracle for me.  i take it with abilify (5 mgs) - and it has been a god-send.  i was on a triple combination of cymbalta, welbutrin and abilify and still did not feel well.  pristiq has helped me tremendously from within a week of onset.  i have struggled with depression since 1991 - and have been on a variety of &quot;cocktails&quot; but this one is working the best so far.  i still struggle with sleep and anxiety - as i have problems with doctors treating my anxiety disorder as it should be.  interesting that physicians will treat some things an not others.  my only complaint is lacking in sleep - other wise i would recommend this medicine to anyone struggling with depression."