"i&#039;ve been taking this medication for 3 weeks. first week i was on 30 mg, i felt almost immediate relief from my anxiety/depression. the first six days i experienced fatigue and slept 12  hours a day. by 7th day i was sleeping less and feeling more emotionally balanced. second week, my dosage was increased to 60 mg and the same thing happened. i slept 12  for about 6 days and by the 7th day i felt good and was sleeping normally. i do have some clenching of my jaw and dry mouth, but a glass of water seems to help. i take my medication at the same time every morning after eating and drink lots of water throughout the day. i&#039;m not taking any other drugs.  i&#039;ve found great relief with cymbalta. my husband is thrilled with the calmer, happier me. me too!"