"i have been taking zoloft for 10  years. i take 100 mg daily. i have found that all of my symptoms have diminished. in times real stress, i take an extra pill. all i can say is that none of the previous drugs i took helped me at all. i have depression and post traumatic stress disorder. at age 59 i still react to anything that sounds like gunfire. i spent 33 years working for the government, 2 in the army the rest in law enforcement. i have found that i have no issues to deal with. i did once while out of the country lose my prescription while backpacking. it was horrible for me and my two friends. i take my pill in the evening before bed. no side effects at all. i found zoloft to be a god send for me."