"i took 150 mg wellbutrin xr (bupropion) for about three or four years. my doc upped the medicine to 300 mg and with that came a twitching side effect. this side effect actually went unnoticed for a while but then it started becoming more pronounced with time. it only affected my face which made it scarier. stuttering, trouble swallowing, and tourette-like uncontrollable movements on the right side of my face were some of my experiences. i have to say this medicine worked very well for me for a long time. i would even encourage others to use this medicine but everyone is different and the 300 mg dose just pushed my body over the edge."