"i was on ortho tri-cyclen for over a year. it did what it had to do which was to prevent pregnancy. during the use of the birth control, i had mild spotting in between periods as well as some cramping. but i became very depressed and emotional. anything would set me off. i would be happy one moment then i would start crying. now i&#039;ve been off for two months and my family and friends can tell the difference."