"i was on the depo shot for 11 years. i never had a period the entire time. it made me moody, psycho and out of control crazy. it made me gain weight (from 95lbs when i started the shot to 133lbs when i stopped it). i am 5 ft 3 with a very small frame, 133 lbs is too much for my body. talked to my dr. and got lutera instead. it is very low hormones. i can honestly say that the depo made me crazy. this pill has changed that. in the first month i noticed the improvement in my moods. my breast size increased from b to c, although tenderness occurs occasionally. has helped grow my hair, and has regulated my periods."