"i was having pretty severe post surgical pain. oxycontin gave me a pounding headache and caused depression and insomnia. tramadol did not help. i started taking nucynta 50mg yesterday. i must say it on a scale of 1 to 10 my pain is now a negative 10! when it wears off its pretty sharp and uncomfortable. taking 1 50mg tab every 4-6 hours. dr said i can take 2 pills but haven&#039;t needed to. i recommend this for anyone who has issues with the usual pain medicines. i have also been drinking prune juice because it does have constipation effect."