"i have been on 3 ocp&#039;s: apri, aviane and lo loestrin fe.i was not able to tolerate apri and aviane. my side effects included depression and general feeling of sickness: headache and extreme nausea.  change in mood: hypersensitivity. increase in breast size,but  no breast sensitivity . no skin breakout or acne.the women in my family suffer from depression, anxiety and are not able to tolerate ocp&#039;s very well. after consulting with my gyne she recommended lo loestrin fe. i&#039;ve only been on lo loestrin fe for 3 days. so far, i&#039;ve had a great experience . the only minor effect, but tolerable, are: night sweats, i take the pill @9 pm, slight increase in anxiety +slight stomach upset . gyne gave me a sample,  so i&#039;m unsure of price w/ insurance"