Ahead of the Curve: David Baltimore's Life in Science
Shane Crotty
University of California Press
In 1950s, Watson and Crick established a so-called "central dogma" in molecular biology: DNA makes RNA, and RNA makes proteins. However, around 1970, two groups in US found the first exception of this rule. David Baltimore's and Howard Temin's teams discovered that RNA makes DNA! This unexpected finding of theirs in cancer-causing RNA viruses not only made this field up-side down, but also opened a new avenue called "recombinant technology" a decade later, for cloning genes and transfering any gene from one species to another almost at will. For this reason, Baltimore and Temin shared a Nobel prize in 1975. Baltimore's greatness extended beyond the science. He viewed this world in an "unconventional" manner. He married a highly-talented Chinese biologist, and protested against the highly controversial US wars in Vietnam and Iraq. He has an exceptional wisdom which we could learn from this well-written biography.