Simple Question (Direct)
Simple Question
Q23502554
P702
Q863908
USER
Which gene encodes transcription termination factor Rho    EF1170 ?
(Q23502554,P702,c(Q863908))
action filter_type
action find
entity Q23502554
relation P702
type Q863908
['Q23502554', 'P702', {'concept': 'Q863908'}]
SELECT DISTINCT ?l WHERE { resource:Q23502554 property:P702 ?l . ?l rdf:type ontology:Q863908 }
transcription termination factor Rho    EF1170
action filter_type
action find
entity transcription termination factor Rho    EF1170
relation encoded by
type nucleic acid sequence
['transcription termination factor Rho    EF1170', 'encoded by', {'concept': 'nucleic acid sequence'}]
SELECT DISTINCT ?l WHERE { resource:transcription_termination_factor_Rho____EF1170 property:encoded_by ?l . ?l rdf:type ontology:nucleic_acid_sequence }
[]
nucleic acid sequence
Q23178123
SYSTEM
transcription termination factor Rho    EF1170
Q23178123
(Q23502554,P702,c(Q863908))
action filter_type
action find
entity Q23502554
relation P702
type Q863908
En transcription termination factor Rho EF1170 encodes transcription termination factor Rho EF1170
['Q23502554', 'P702', {'concept': 'Q863908'}]
SELECT DISTINCT ?l WHERE { resource:Q23502554 property:P702 ?l . ?l rdf:type ontology:Q863908 }
transcription termination factor Rho    EF1170
En transcription termination factor Rho EF1170 encodes transcription termination factor Rho EF1170
transcription termination factor Rho    EF1170
action filter_type
action find
entity transcription termination factor Rho    EF1170
relation encoded by
type nucleic acid sequence
['transcription termination factor Rho    EF1170', 'encoded by', {'concept': 'nucleic acid sequence'}]
SELECT DISTINCT ?l WHERE { resource:transcription_termination_factor_Rho____EF1170 property:encoded_by ?l . ?l rdf:type ontology:nucleic_acid_sequence }
[]
Simple Question (Direct)
Simple Question|Single Entity
Q23502554
P703
Q631147
USER
What is the taxon to which transcription termination factor Rho    EF1170 belongs to ?
(Q23502554,P703,c(Q631147))
action filter_type
action find
entity Q23502554
relation P703
type Q631147
['Q23502554', 'P703', {'concept': 'Q631147'}]
SELECT DISTINCT ?g WHERE { resource:Q23502554 property:P703 ?g . ?g rdf:type ontology:Q631147 }
transcription termination factor Rho    EF1170
action filter_type
action find
entity transcription termination factor Rho    EF1170
relation found in taxon
type infraspecific name
['transcription termination factor Rho    EF1170', 'found in taxon', {'concept': 'infraspecific name'}]
SELECT DISTINCT ?g WHERE { resource:transcription_termination_factor_Rho____EF1170 property:found_in_taxon ?g . ?g rdf:type ontology:infraspecific_name }
[]
infraspecific name
Q21102965
SYSTEM
Enterococcus faecalis V583
Q21102965
(Q23502554,P703,c(Q631147))
action filter_type
action find
entity Q23502554
relation P703
type Q631147
[ANSWER]
['Q23502554', 'P703', {'concept': 'Q631147'}]
SELECT DISTINCT ?g WHERE { resource:Q23502554 property:P703 ?g . ?g rdf:type ontology:Q631147 }
Enterococcus faecalis V583
Enterococcus faecalis V583
Enterococcus faecalis V583
action filter_type
action find
entity transcription termination factor Rho    EF1170
relation found in taxon
type infraspecific name
['transcription termination factor Rho    EF1170', 'found in taxon', {'concept': 'infraspecific name'}]
SELECT DISTINCT ?g WHERE { resource:transcription_termination_factor_Rho____EF1170 property:found_in_taxon ?g . ?g rdf:type ontology:infraspecific_name }
[]
Quantitative Reasoning (Count) (All)
Quantitative|Count over Atleast/ Atmost/ Approx. the same/Equal|Mult. entity type
P129
Q181394 Q8386 Q79529
USER
How many nutrients do approximately 43 drugs and chemical substances contact with ?
(c(Q8386)|c(Q79529),P129,c(Q181394))
action count
action approx
action union
action find_reverse_tuple_counts
relation P129
type Q181394
type Q8386
action find_reverse_tuple_counts
relation P129
type Q181394
type Q79529
value 43
[[{'concept': 'Q8386'}, {'concept': 'Q79529'}], 'P129', {'concept': 'Q181394'}]
SELECT DISTINCT ( COUNT ( ?e ) AS ?c ) WHERE { { SELECT DISTINCT ?e ( COUNT ( ?u ) AS ?o ) WHERE { VALUES ( ?q ) { ( ontology:Q8386 ) ( ontology:Q79529 ) } . ?u rdf:type ?q } GROUP BY ?e } . FILTER ( ?o = 43 ) }
action count
action approx
action union
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type drug
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type chemical substance
value 43
[[{'concept': 'drug'}, {'concept': 'chemical substance'}], 'physically interacts with', {'concept': 'nutrient'}]
SELECT DISTINCT ( COUNT ( ?e ) AS ?c ) WHERE { { SELECT DISTINCT ?e ( COUNT ( ?u ) AS ?o ) WHERE { VALUES ( ?q ) { ( ontology:drug ) ( ontology:chemical_substance ) } . ?u rdf:type ?q } GROUP BY ?e } . FILTER ( ?o = 43 ) }
[]
nutrient drug chemical substance
SYSTEM
7
Q309513 Q288797 Q21115051 Q21115052 Q21109355 Q21110872 Q21109363
(c(Q8386)|c(Q79529),P129,c(Q181394))
action count
action approx
action union
action find_reverse_tuple_counts
relation P129
type Q181394
type Q8386
action find_reverse_tuple_counts
relation P129
type Q181394
type Q79529
value 43
[ANSWER]
[[{'concept': 'Q8386'}, {'concept': 'Q79529'}], 'P129', {'concept': 'Q181394'}]
SELECT DISTINCT ( COUNT ( ?e ) AS ?c ) WHERE { { SELECT DISTINCT ?e ( COUNT ( ?u ) AS ?o ) WHERE { VALUES ( ?q ) { ( ontology:Q8386 ) ( ontology:Q79529 ) } . ?u rdf:type ?q } GROUP BY ?e } . FILTER ( ?o = 43 ) }
Histamine H1 receptor 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 7 D(3) dopamine receptor 5-hydroxytryptamine receptor 6
7
action count
action approx
action union
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type drug
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type chemical substance
value 43
[[{'concept': 'drug'}, {'concept': 'chemical substance'}], 'physically interacts with', {'concept': 'nutrient'}]
SELECT DISTINCT ( COUNT ( ?e ) AS ?c ) WHERE { { SELECT DISTINCT ?e ( COUNT ( ?u ) AS ?o ) WHERE { VALUES ( ?q ) { ( ontology:drug ) ( ontology:chemical_substance ) } . ?u rdf:type ?q } GROUP BY ?e } . FILTER ( ?o = 43 ) }
[]
Logical Reasoning (All)
Logical|Union|Single_Relation
Q21094629 Q23178123
P688
Q181394
USER
Which nutrients are encoded by transcription termination factor Rho    EF1170 or cysteine desulfurase    CT_687 ?
OR((Q23178123,P688,c(Q181394)), (Q21094629,P688,c(Q181394)))
action filter_type
action union
action find
entity Q23178123
relation P688
action find
entity Q21094629
relation P688
type Q181394
{'OR': [['Q23178123', 'P688', {'concept': 'Q181394'}], ['Q21094629', 'P688', {'concept': 'Q181394'}]]}
SELECT DISTINCT ?b WHERE { { { resource:Q21094629 property:P688 ?b } UNION { resource:Q23178123 property:P688 ?b } } . ?b rdf:type ontology:Q181394 }
cysteine desulfurase    CT_687 transcription termination factor Rho    EF1170
action filter_type
action union
action find
entity transcription termination factor Rho    EF1170
relation encodes
action find
entity cysteine desulfurase    CT_687
relation encodes
type nutrient
{'OR': [['transcription termination factor Rho    EF1170', 'encodes', {'concept': 'nutrient'}], ['cysteine desulfurase    CT_687', 'encodes', {'concept': 'nutrient'}]]}
SELECT DISTINCT ?b WHERE { { { resource:cysteine_desulfurase____CT_687 property:encodes ?b } UNION { resource:transcription_termination_factor_Rho____EF1170 property:encodes ?b } } . ?b rdf:type ontology:nutrient }
[]
nutrient
Q21168495 Q23502554
SYSTEM
cysteine desulfurase    CT_687, transcription termination factor Rho    EF1170
Q21168495 Q23502554
OR((Q23178123,P688,c(Q181394)), (Q21094629,P688,c(Q181394)))
action filter_type
action union
action find
entity Q23178123
relation P688
action find
entity Q21094629
relation P688
type Q181394
[ANSWERS]
{'OR': [['Q23178123', 'P688', {'concept': 'Q181394'}], ['Q21094629', 'P688', {'concept': 'Q181394'}]]}
SELECT DISTINCT ?b WHERE { { { resource:Q21094629 property:P688 ?b } UNION { resource:Q23178123 property:P688 ?b } } . ?b rdf:type ontology:Q181394 }
cysteine desulfurase    CT_687 transcription termination factor Rho    EF1170
Cysteine desulfurase CT 687 and transcription termination factor Rho EF1170 are encoded by transcription termination factor Rho EF1170 or cysteine desulfurase CT_687
cysteine desulfurase    CT_687 transcription termination factor Rho    EF1170
action filter_type
action union
action find
entity transcription termination factor Rho    EF1170
relation encodes
action find
entity cysteine desulfurase    CT_687
relation encodes
type nutrient
{'OR': [['transcription termination factor Rho    EF1170', 'encodes', {'concept': 'nutrient'}], ['cysteine desulfurase    CT_687', 'encodes', {'concept': 'nutrient'}]]}
SELECT DISTINCT ?b WHERE { { { resource:cysteine_desulfurase____CT_687 property:encodes ?b } UNION { resource:transcription_termination_factor_Rho____EF1170 property:encodes ?b } } . ?b rdf:type ontology:nutrient }
[]
Quantitative Reasoning (All)
Quantitative|Atleast/ Atmost/ Approx. the same/Equal|Mult. entity type
P129
Q181394 Q8386 Q181394
USER
Which nutrients do atleast 16 drugs and nutrients interact with ?
(c(Q8386)|c(Q181394),P129,c(Q181394))
action atleast
action union
action find_reverse_tuple_counts
relation P129
type Q181394
type Q8386
action find_reverse_tuple_counts
relation P129
type Q181394
type Q181394
value 16
[[{'concept': 'Q8386'}, {'concept': 'Q181394'}], 'P129', {'concept': 'Q181394'}]
SELECT DISTINCT ?l WHERE { { SELECT DISTINCT ?l ( COUNT ( ?f ) AS ?i ) WHERE { VALUES ( ?v ) { ( ontology:Q8386 ) ( ontology:Q181394 ) } . ?f rdf:type ?v } GROUP BY ?l } . FILTER ( ?i >= 16 ) }
action atleast
action union
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type drug
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type nutrient
value 16
[[{'concept': 'drug'}, {'concept': 'nutrient'}], 'physically interacts with', {'concept': 'nutrient'}]
SELECT DISTINCT ?l WHERE { { SELECT DISTINCT ?l ( COUNT ( ?f ) AS ?i ) WHERE { VALUES ( ?v ) { ( ontology:drug ) ( ontology:nutrient ) } . ?f rdf:type ?v } GROUP BY ?l } . FILTER ( ?i >= 16 ) }
[]
nutrient drug nutrient
Q2034004 Q1949517 Q4639596
SYSTEM
D(2) dopamine receptor, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B
Q7050954 Q309513 Q308856 Q287961 Q2663095 Q5123372 Q410142 Q288797 Q287958 Q21126810 Q21110867 Q4639596 Q4734884 Q4734887 Q4734886 Q21115051 Q21115052 Q415364 Q21109355 Q4734894 Q21110872 Q4734892 Q21108118 Q4734891 Q21115046 Q21115043 Q1949517 Q21109363 Q2034004
(c(Q8386)|c(Q181394),P129,c(Q181394))
action atleast
action union
action find_reverse_tuple_counts
relation P129
type Q181394
type Q8386
action find_reverse_tuple_counts
relation P129
type Q181394
type Q181394
value 16
Atleast 16 drugs and nutrients interact with [ANSWERS]
[[{'concept': 'Q8386'}, {'concept': 'Q181394'}], 'P129', {'concept': 'Q181394'}]
SELECT DISTINCT ?l WHERE { { SELECT DISTINCT ?l ( COUNT ( ?f ) AS ?i ) WHERE { VALUES ( ?v ) { ( ontology:Q8386 ) ( ontology:Q181394 ) } . ?f rdf:type ?v } GROUP BY ?l } . FILTER ( ?i >= 16 ) }
Sodium-dependent noradrenaline transporter Histamine H1 receptor D(4) dopamine receptor Beta-2 adrenergic receptor Glucocorticoid receptor Mu-type opioid receptor Sodium-dependent serotonin transporter 5-hydroxytryptamine receptor 1B Beta-1 adrenergic receptor Prostaglandin G/H synthase 1 D(1A) dopamine receptor 5-hydroxytryptamine receptor 2B Alpha-1A adrenergic receptor Alpha-1D adrenergic receptor Alpha-1B adrenergic receptor 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F Prostaglandin G/H synthase 2 5-hydroxytryptamine receptor 7 Alpha-2B adrenergic receptor D(3) dopamine receptor Alpha-2A adrenergic receptor 5-hydroxytryptamine receptor 2C Alpha-2C adrenergic receptor 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 6 D(2) dopamine receptor
Atleast 16 drugs and nutrients interact with D(2) dopamine receptor, 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2B
D(2) dopamine receptor 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B
action atleast
action union
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type drug
action find_reverse_tuple_counts
relation physically interacts with
type nutrient
type nutrient
value 16
[[{'concept': 'drug'}, {'concept': 'nutrient'}], 'physically interacts with', {'concept': 'nutrient'}]
SELECT DISTINCT ?l WHERE { { SELECT DISTINCT ?l ( COUNT ( ?f ) AS ?i ) WHERE { VALUES ( ?v ) { ( ontology:drug ) ( ontology:nutrient ) } . ?f rdf:type ?v } GROUP BY ?l } . FILTER ( ?i >= 16 ) }
[]
Clarification
Comparative|More/Less|Mult. entity type|Indirect
P129
Q181394 Q8386 Q181394
USER
Which nutrients contact greater number of nutrients and drugs than that nutrient ?
(c(Q181394),P129,c(Q181394)|c(Q8386))
[{'concept': 'Q181394'}, 'P129', [{'concept': 'Q181394'}, {'concept': 'Q8386'}]]
SELECT DISTINCT ?z WHERE { { { ?z property:P129 ?z } UNION { ?z property:P129 ?y } } . ?z rdf:type ontology:Q181394 . ?y rdf:type ontology:Q8386 }
[{'concept': 'nutrient'}, 'physically interacts with', [{'concept': 'nutrient'}, {'concept': 'drug'}]]
SELECT DISTINCT ?z WHERE { { { ?z property:physically_interacts_with ?z } UNION { ?z property:physically_interacts_with ?y } } . ?z rdf:type ontology:nutrient . ?y rdf:type ontology:drug }
[]
nutrient drug nutrient
Comparative|More/Less|Mult. entity type|Clarification
Q1949517
SYSTEM
Did you mean 5-hydroxytryptamine receptor 2A ?
(c(Q181394),P129,c(Q181394)|c(Q8386))
[ANSWER]
[{'concept': 'Q181394'}, 'P129', [{'concept': 'Q181394'}, {'concept': 'Q8386'}]]
SELECT DISTINCT ?z WHERE { { { ?z property:P129 ?z } UNION { ?z property:P129 ?y } } . ?z rdf:type ontology:Q181394 . ?y rdf:type ontology:Q8386 }
Did you mean 5-hydroxytryptamine receptor 2A ?
5-hydroxytryptamine receptor 2A
[{'concept': 'nutrient'}, 'physically interacts with', [{'concept': 'nutrient'}, {'concept': 'drug'}]]
SELECT DISTINCT ?z WHERE { { { ?z property:physically_interacts_with ?z } UNION { ?z property:physically_interacts_with ?y } } . ?z rdf:type ontology:nutrient . ?y rdf:type ontology:drug }
[]
Comparative Reasoning (All)
USER
Yes
(c(Q181394),P129,c(Q181394)|c(Q8386))
[{'concept': 'Q181394'}, 'P129', [{'concept': 'Q181394'}, {'concept': 'Q8386'}]]
[{'concept': 'nutrient'}, 'physically interacts with', [{'concept': 'nutrient'}, {'concept': 'drug'}]]
[]
SYSTEM
285
Q21115605 Q21110942 Q7050954 Q21116154 Q309513 Q21173427 Q308856 Q21982207 Q4847910 Q2271947 Q21109971 Q13561329 Q7671480 Q21987850 Q423701 Q287961 Q2663095 Q905729 Q21497881 Q21173164 Q21120422 Q21120424 Q417057 Q21154358 Q6155969 Q5123372 Q1499998 Q7553281 Q21108624 Q21156477 Q410142 Q420470 Q288797 Q21135205 Q424440 Q21172390 Q21494481 Q1486720 Q4789588 Q21107843 Q4789584 Q21113671 Q4822789 Q287958 Q1084878 Q21108402 Q21126810 Q14900999 Q415287 Q7671479 Q21136123 Q7169506 Q415607 Q21109365 Q254943 Q21107439 Q15323278 Q21110867 Q21102152 Q21103155 Q21109974 Q2398308 Q5038044 Q21109218 Q5201199 Q905736 Q21122995 Q21135975 Q415976 Q21496563 Q15323770 Q21102124 Q21107885 Q21123244 Q21107890 Q410798 Q21103207 Q21110467 Q21119828 Q21119820 Q21118920 Q6414726 Q21107812 Q4847900 Q4847907 Q21108482 Q7671495 Q21121815 Q7671493 Q4639596 Q21097491 Q21111162 Q21116946 Q21114332 Q21987842 Q21982210 Q6901317 Q416601 Q417149 Q5401858 Q5401857 Q21120458 Q4734884 Q4734887 Q4734886 Q5005897 Q21988386 Q22676679 Q21173381 Q5514257 Q21987844 Q21987843 Q21119575 Q21497890 Q21126777 Q21116162 Q21110396 Q21116164 Q21991513 Q417801 Q2844056 Q21120420 Q5773155 Q21173310 Q5500222 Q7390898 Q21111803 Q21112690 Q21120423 Q22679015 Q21174687 Q21125248 Q21115334 Q14905969 Q21118353 Q7799753 Q21175110 Q21173406 Q21119818 Q21115051 Q21115052 Q909409 Q5513985 Q21108338 Q415364 Q21109355 Q21109354 Q21115954 Q409867 Q4734894 Q21110872 Q4734892 Q21103146 Q21114578 Q3454525 Q21108118 Q21120955 Q4734891 Q21114576 Q21108785 Q14905748 Q3271551 Q21990456 Q21131500 Q21498865 Q21123247 Q21123242 Q128861 Q21132004 Q12746111 Q21119156 Q2819188 Q21119157 Q21122493 Q7671468 Q4897175 Q21102111 Q412214 Q1085078 Q7673856 Q21103198 Q21118862 Q21110936 Q22677167 Q21132917 Q21132915 Q6592965 Q905000 Q21115961 Q21115962 Q21115965 Q14905076 Q21105176 Q14912057 Q8083989 Q21498709 Q21102075 Q21497878 Q21119653 Q21124409 Q21173485 Q5773160 Q21111833 Q21122997 Q3062781 Q21125253 Q12746120 Q11071075 Q6449561 Q21111336 Q7799751 Q21138907 Q5629167 Q21115815 Q21115816 Q21115819 Q21122921 Q21121233 Q21110532 Q21159525 Q21108125 Q5446453 Q21115046 Q21115043 Q415271 Q7834290 Q21109026 Q1500004 Q21114582 Q408572 Q21497939 Q3454531 Q21497937 Q21497936 Q21982979 Q21121086 Q21109462 Q21102082 Q21984577 Q904925 Q3415811 Q424401 Q5009781 Q21173206 Q21173207 Q2521094 Q285613 Q904241 Q21174141 Q21130911 Q423561 Q21120051 Q587961 Q22676802 Q21118576 Q15324694 Q21096394 Q21201294 Q21496564 Q7671477 Q21127141 Q21111265 Q21116665 Q1949517 Q15327766 Q21118976 Q21498666 Q21109363 Q21109359 Q6592976 Q21157551 Q21102146 Q21103162 Q21121816 Q410434 Q6449560 Q21100360 Q21984383 Q21125499 Q5201201 Q5520260 Q2034004 Q21134814 Q21118710 Q418781
(c(Q181394),P129,c(Q181394)|c(Q8386))
[ANSWER]
[{'concept': 'Q181394'}, 'P129', [{'concept': 'Q181394'}, {'concept': 'Q8386'}]]
SELECT DISTINCT ?z WHERE { { { ?z property:P129 ?z } UNION { ?z property:P129 ?y } } . ?z rdf:type ontology:Q181394 . ?y rdf:type ontology:Q8386 }
Vascular endothelial growth factor receptor 1 G-protein coupled receptor 55 Sodium-dependent noradrenaline transporter Adenosine receptor A3 Histamine H1 receptor Histone deacetylase 9 D(4) dopamine receptor Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Muscarinic acetylcholine receptor M2 Sodium-dependent dopamine transporter Cation channel sperm-associated protein 4 Reelin Transient receptor potential cation channel subfamily M member 4 Prostaglandin E2 receptor EP2 subtype Coagulation factor X Beta-2 adrenergic receptor Glucocorticoid receptor Prostaglandin D2 receptor G protein-activated inward rectifier potassium channel 4 Carbonic anhydrase 1 Prostaglandin E2 receptor EP4 subtype Prostaglandin E2 receptor EP2 subtype Vitamin D3 receptor Histone deacetylase 3 Tyrosine-protein kinase JAK3 Mu-type opioid receptor Voltage-dependent L-type calcium channel subunit alpha-1C Solute carrier family 12 member 3 Platelet-derived growth factor receptor beta Hydroxycarboxylic acid receptor 1 Sodium-dependent serotonin transporter Cystic fibrosis transmembrane conductance regulator 5-hydroxytryptamine receptor 1B Dihydroorotate dehydrogenase (quinone), mitochondrial Cytochrome P450 3A4 Vascular endothelial growth factor receptor 2 Uracil nucleotide/cysteinyl leukotriene receptor Glutamate receptor 3 Vasopressin V2 receptor Potassium voltage-gated channel subfamily A member 10 Vasopressin V1a receptor ATP-binding cassette sub-family C member 8 Toll-like receptor 7 Beta-1 adrenergic receptor Peroxisome proliferator-activated receptor gamma Chloride channel protein 2 Prostaglandin G/H synthase 1 Kappa-type opioid receptor Aromatase Transient receptor potential cation channel subfamily M member 3 Solute carrier organic anion transporter family member 2B1 Peroxisome proliferator-activated receptor alpha 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5-hydroxytryptamine receptor 4 Retinoic acid receptor alpha Farnesyl pyrophosphate synthase Transient receptor potential cation channel subfamily A member 1 D(1A) dopamine receptor Voltage-dependent T-type calcium channel subunit alpha-1I Glycine receptor subunit alpha-1 Cation channel sperm-associated protein 3 P2Y purinoceptor 12 Carbonic anhydrase 4 Serine/threonine-protein kinase B-raf Cysteinyl leukotriene receptor 2 Prostacyclin receptor Melatonin receptor type 1A Multidrug and toxin extrusion protein 1 Proto-oncogene tyrosine-protein kinase receptor Ret Potassium voltage-gated channel subfamily C member 1 Transient receptor potential cation channel subfamily M member 4 Voltage-dependent L-type calcium channel subunit alpha-1F Potassium voltage-gated channel subfamily B member 2 cGMP-inhibited 3',5'-cyclic phosphodiesterase B Potassium voltage-gated channel subfamily A member 7 cGMP-specific 3',5'-cyclic phosphodiesterase G-protein coupled bile acid receptor 1 Potassium-transporting ATPase alpha chain 1 ATP-sensitive inward rectifier potassium channel 8 Potassium channel subfamily K member 2 P2X purinoceptor 3 ATP-sensitive inward rectifier potassium channel 11 Inositol 1,4,5-trisphosphate receptor type 1 Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M4 DNA topoisomerase 2-alpha Transient receptor potential cation channel subfamily M member 8 P2Y purinoceptor 11 Transient receptor potential cation channel subfamily M member 7 5-hydroxytryptamine receptor 2B Sodium/potassium-transporting ATPase subunit alpha-1 Acetylcholine receptor subunit alpha Carbonic anhydrase 12 Tubulin beta chain Prostaglandin E2 receptor EP3 subtype Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Amine oxidase [flavin-containing] A Androgen receptor Dihydrofolate reductase Estrogen receptor Estrogen receptor beta Proteasome subunit beta type-5 Alpha-1A adrenergic receptor Alpha-1D adrenergic receptor Alpha-1B adrenergic receptor Hepatocyte growth factor receptor Delta-type opioid receptor Acetylcholinesterase Histone deacetylase 6 G-protein coupled estrogen receptor 1 Prostaglandin E2 receptor EP1 subtype Prostaglandin E2 receptor EP4 subtype P2Y purinoceptor 1 ATP-sensitive inward rectifier potassium channel 8 P2Y purinoceptor 2 Adenosine receptor A2a Peptidyl-prolyl cis-trans isomerase FKBP1A Adenosine receptor A2b Trace amine-associated receptor 4 Extracellular calcium-sensing receptor Muscarinic acetylcholine receptor M3 Prostaglandin E2 receptor EP1 subtype Histone deacetylase 2 Endothelin B receptor Free fatty acid receptor 1 Sodium/glucose cotransporter 2 Voltage-dependent L-type calcium channel subunit alpha-1S fMet-Leu-Phe receptor Prostaglandin E2 receptor EP3 subtype Cholinesterase Sodium/bile acid cotransporter Solute carrier organic anion transporter family member 1B3 Delta-type opioid receptor Potassium voltage-gated channel subfamily A member 1 Vascular endothelial growth factor receptor 3 Thyroid hormone receptor beta Vitamin K epoxide reductase complex subunit 1 Histone deacetylase 8 Intermediate conductance calcium-activated potassium channel protein 4 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F Mast/stem cell growth factor receptor Kit Gonadotropin-releasing hormone receptor Ribonucleoside-diphosphate reductase subunit M2 Prostaglandin G/H synthase 2 5-hydroxytryptamine receptor 7 Proto-oncogene tyrosine-protein kinase Src Glycine receptor subunit alpha-2 Nuclear receptor subfamily 1 group I member 2 Alpha-2B adrenergic receptor D(3) dopamine receptor Alpha-2A adrenergic receptor Glycine receptor subunit alpha-3 Gamma-aminobutyric acid receptor subunit alpha-3 Progesterone receptor 5-hydroxytryptamine receptor 2C Nuclear receptor subfamily 2 group C member 2 Alpha-2C adrenergic receptor Gamma-aminobutyric acid receptor subunit alpha-5 Potassium voltage-gated channel subfamily KQT member 4 Voltage-dependent L-type calcium channel subunit alpha-1C Smoothened homolog Prostaglandin D2 receptor 2 D(1B) dopamine receptor Beta-3 adrenergic receptor cGMP-inhibited 3',5'-cyclic phosphodiesterase A cAMP-specific 3',5'-cyclic phosphodiesterase 4B Angiotensin-converting enzyme Endothelin-1 receptor Motilin receptor Inosine-5'-monophosphate dehydrogenase 2 Type-1 angiotensin II receptor Inosine-5'-monophosphate dehydrogenase 1 Prostaglandin F2-alpha receptor Short transient receptor potential channel 5 Beta-3 adrenergic receptor Acid-sensing ion channel 3 Dipeptidyl peptidase 4 Bile acid receptor Substance-P receptor G-protein coupled receptor family C group 6 member A Glutamate receptor ionotropic, NMDA 1 G-protein coupled receptor 35 Thyroid peroxidase Carbonic anhydrase 14 Carbonic anhydrase 7 Retinoic acid receptor gamma Potassium voltage-gated channel subfamily H member 2 Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor 4 Nuclear receptor subfamily 1 group I member 2 Anoctamin-1 ATP-sensitive inward rectifier potassium channel 11 Kappa-type opioid receptor Adenosine receptor A2b Acid-sensing ion channel 1 G protein-activated inward rectifier potassium channel 2 Solute carrier family 12 member 2 Solute carrier family 12 member 1 Hydroxycarboxylic acid receptor 2 Histone deacetylase 5 Cation channel sperm-associated protein 2 Melatonin receptor type 1B Adenosine receptor A1 Solute carrier organic anion transporter family member 1B1 Muscarinic acetylcholine receptor M5 Trace amine-associated receptor 1 Potassium voltage-gated channel subfamily KQT member 2 ALK tyrosine kinase receptor Thyroid hormone receptor alpha Ryanodine receptor 1 Histone deacetylase 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Chromaffin granule amine transporter Ribonucleoside-diphosphate reductase large subunit Potassium voltage-gated channel subfamily H member 1 Ryanodine receptor 3 5-hydroxytryptamine receptor 3A Fibroblast growth factor receptor 1 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1A Receptor tyrosine-protein kinase erbB-2 Transient receptor potential cation channel subfamily A member 1 Tryptase alpha/beta-1 Nuclear receptor subfamily 1 group I member 3 Gamma-aminobutyric acid receptor subunit alpha-2 Sigma non-opioid intracellular receptor 1 5-hydroxytryptamine receptor 7 Mineralocorticoid receptor 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 3A Alpha-1B adrenergic receptor Proton-coupled folate transporter Amine oxidase [flavin-containing] B Acid-sensing ion channel 2 Potassium voltage-gated channel subfamily D member 3 Cytochrome P450 11B1, mitochondrial Ryanodine receptor 2 Epidermal growth factor receptor Receptor-type tyrosine-protein kinase FLT3 Histone deacetylase 4 Histone deacetylase 7 Synaptic vesicular amine transporter Serine/threonine-protein kinase mTOR Sodium/glucose cotransporter 1 Prostaglandin D2 receptor 2 Glutamate receptor ionotropic, NMDA 2D Lysosomal protective protein Retinoic acid receptor RXR-gamma Tyrosine-protein kinase ABL1 Thymidylate synthase Potassium channel subfamily T member 1 Transient receptor potential cation channel subfamily V member 3 Potassium voltage-gated channel subfamily A member 5 Cannabinoid receptor 1 Potassium voltage-gated channel subfamily A member 7 Transient receptor potential cation channel subfamily M member 2 Sodium-coupled monocarboxylate transporter 1 Cation channel sperm-associated protein 1 Dual specificity mitogen-activated protein kinase kinase 2 5-hydroxytryptamine receptor 2A Transient receptor potential cation channel subfamily V member 5 Probable G-protein coupled receptor 139 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 5A Retinoic acid receptor beta Histone deacetylase 10 Voltage-dependent L-type calcium channel subunit alpha-1D Glycine receptor subunit beta P2Y purinoceptor 13 RAF proto-oncogene serine/threonine-protein kinase Potassium voltage-gated channel subfamily KQT member 1 Dual specificity mitogen-activated protein kinase kinase 1 Voltage-dependent L-type calcium channel subunit alpha-1F Trypsin-1 Cysteinyl leukotriene receptor 1 Gamma-aminobutyric acid receptor subunit alpha-1 D(2) dopamine receptor Equilibrative nucleoside transporter 4 Retinoic acid receptor RXR-alpha Catechol O-methyltransferase
285
[{'concept': 'nutrient'}, 'physically interacts with', [{'concept': 'nutrient'}, {'concept': 'drug'}]]
SELECT DISTINCT ?z WHERE { { { ?z property:physically_interacts_with ?z } UNION { ?z property:physically_interacts_with ?y } } . ?z rdf:type ontology:nutrient . ?y rdf:type ontology:drug }
[]
Logical Reasoning (All)
Logical|Union|Single_Relation
Q21120051 Q1949517
P129
Q8386
USER
Which drugs communicates with 5-hydroxytryptamine receptor 2A or Retinoic acid receptor RXR-gamma ?
OR((c(Q8386),P129,Q1949517), (c(Q8386),P129,Q21120051))
action filter_type
action union
action find_reverse
entity Q1949517
relation P129
action find_reverse
entity Q21120051
relation P129
type Q8386
{'OR': [[{'concept': 'Q8386'}, 'P129', 'Q1949517'], [{'concept': 'Q8386'}, 'P129', 'Q21120051']]}
SELECT DISTINCT ?c WHERE { ?c rdf:type ontology:Q8386 . { { ?c property:P129 resource:Q1949517 } UNION { ?c property:P129 resource:Q21120051 } } }
Retinoic acid receptor RXR-gamma 5-hydroxytryptamine receptor 2A
action filter_type
action union
action find_reverse
entity 5-hydroxytryptamine receptor 2A
relation physically interacts with
action find_reverse
entity Retinoic acid receptor RXR-gamma
relation physically interacts with
type drug
{'OR': [[{'concept': 'drug'}, 'physically interacts with', '5-hydroxytryptamine receptor 2A'], [{'concept': 'drug'}, 'physically interacts with', 'Retinoic acid receptor RXR-gamma']]}
SELECT DISTINCT ?c WHERE { ?c rdf:type ontology:drug . { { ?c property:physically_interacts_with resource:5-hydroxytryptamine_receptor_2A } UNION { ?c property:physically_interacts_with resource:Retinoic_acid_receptor_RXR-gamma } } }
[]
drug
Q415996 Q424442 Q424477 Q413581 Q407972 Q3563148 Q419186 Q221361 Q418050 Q416632
SYSTEM
Some of them are flibanserin, methysergide, methylergonovine, bromocriptine, chlorpromazine, vortioxetine, ergotamine, clozapine, sertindole, nefazodone
Q58376 Q1752915 Q424446 Q58375 Q423308 Q4927426 Q2608288 Q201872 Q205517 Q407972 Q144085 Q3563148 Q269111 Q423520 Q424442 Q416701 Q226905 Q3008033 Q418192 Q421930 Q593166 Q44931 Q408300 Q7702355 Q3611854 Q418050 Q6824154 Q424477 Q419186 Q23118 Q58614 Q415118 Q251347 Q412443 Q416632 Q408535 Q411932 Q395229 Q411188 Q411457 Q221361 Q418101 Q6821618 Q415752 Q340139 Q415996 Q413581
OR((c(Q8386),P129,Q1949517), (c(Q8386),P129,Q21120051))
action filter_type
action union
action find_reverse
entity Q1949517
relation P129
action find_reverse
entity Q21120051
relation P129
type Q8386
[ANSWERS] communicate with 5-hydroxytryptamine receptor 2A or Retinoic acid receptor RXR-gamma
{'OR': [[{'concept': 'Q8386'}, 'P129', 'Q1949517'], [{'concept': 'Q8386'}, 'P129', 'Q21120051']]}
SELECT DISTINCT ?c WHERE { ?c rdf:type ontology:Q8386 . { { ?c property:P129 resource:Q1949517 } UNION { ?c property:P129 resource:Q21120051 } } }
fluphenazine trifluoperazine lisuride thioridazine cabergoline blonanserin thiothixene Olanzapine ziprasidone chlorpromazine pimozide vortioxetine apomorphine perphenazine methysergide mianserin zotepine Cyamemazine bexarotene mirtazapine molindone sarpogrelate fluspirilene terguride alitretinoin sertindole methiothepin methylergonovine ergotamine LSD loxapine pipamperone haloperidol risperidone nefazodone quetiapine duloxetine agomelatine aripiprazole trazodone clozapine pindolol mesoridazine pergolide lorcaserin flibanserin bromocriptine
Flibanserin, methysergide, methylergonovine, bromocriptine, chlorpromazine, vortioxetine, ergotamine, clozapine, sertindole and nefazodone communicate with 5-hydroxytryptamine receptor 2A or Retinoic acid receptor RXR-gamma
flibanserin methysergide methylergonovine bromocriptine chlorpromazine vortioxetine ergotamine clozapine sertindole nefazodone
action filter_type
action union
action find_reverse
entity 5-hydroxytryptamine receptor 2A
relation physically interacts with
action find_reverse
entity Retinoic acid receptor RXR-gamma
relation physically interacts with
type drug
{'OR': [[{'concept': 'drug'}, 'physically interacts with', '5-hydroxytryptamine receptor 2A'], [{'concept': 'drug'}, 'physically interacts with', 'Retinoic acid receptor RXR-gamma']]}
SELECT DISTINCT ?c WHERE { ?c rdf:type ontology:drug . { { ?c property:physically_interacts_with resource:5-hydroxytryptamine_receptor_2A } UNION { ?c property:physically_interacts_with resource:Retinoic_acid_receptor_RXR-gamma } } }
[]