human
Use the entities and relationships to rewrite the following key sentences to generate independent sentence which don't contains conjunction words for each relationship, the sentence must contain the related entity full name, entity 
abbreviation and relationship type:
Entities: Short-chain fatty acids (Metabolite), G-protein-coupled receptor (Pathway), deacetylase (Protein)
Relationships: G-protein-coupled receptor --[activated_by]-- Short-chain fatty acids, deacetylase --[inhibited_by]-- Short-chain fatty acids
Key Sentences: SCFAs are the primary metabolites of gut bacteria, which are derived from the fermentation of dietary fibers. They activate GPCR signaling, suppress histone HDAC activity, and inhibit inflammation, facilitating the maintenance of gut health and biofunction. The aforementioned gut microbiota dysbiosis reduces SCFA levels. Treatment targeting SCFA/GPCR signaling may alleviate air pollution-associated inflammation and metabolic disorders, which involve lung-gut axis disruption.
gpt
--- Reasoning ---
1. Is the question multiple-choice question?
No
2. Is it implied multiple-choice question?
No
3. If two experts were independently asked the question, will the final answer be exactly the same?
No

--- Answer ---
open