title: IMEP (chemotherapy)
text: # IMEP (chemotherapy)
  
  IMEP is a chemotherapy regimen that is effective for nasal NK- / T-cell lymphoma. This chemotherapy regimen was also tested in Hodgkin disease as a part of a multidrug alternating scheme COPP / ABV / IMEP. But in that setting it showed no advantage in efficacy and toxicity compared to the use of ABVD or the alternating COPP / ABVD scheme.
  
  ## Drug regimen
  
  | Drug | Dose | Mode | Days |
  | - | - | - | - |
  | (I)fosfamide | 1500 $mg/m^2$ with mesna | IV infusion | Days 1-3 |
  | (M)ethotrexate | 30 $mg/m^2$ | IV bolus | Days 3 and 10 |
  | (E)toposide | 100 $mg/m^2$ | IV infusion | Days 1-3 |
  | (P)rednisone | 120 mg | PO qd | Days 1-5 |
  