title: Arthrogryposis–renal dysfunction–cholestasis syndrome
text: # Arthrogryposis–renal dysfunction–cholestasis syndrome
  
  Arthrogryposis–renal dysfunction–cholestasis syndrome is a cutaneous condition caused by a mutation in the VPS33B gene. Most of the cases have been survived for infancy. Recently, College of Medical Sciences in Nepal reports a case of ARC syndrome in a girl at the age of more than 18 years.
  
  